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1

Middleton, Olivia Lane. "A Low-Fat Diet Containing Heated Soybean Oil Promotes Hyperglycemia in C57BL/6J Mice." Digital Archive @ GSU, 2013. http://digitalarchive.gsu.edu/nutrition_theses/49.

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A Low-fat Diet Containing Heated Soybean Oil Promotes Hyperglycemia in C57BL/6J Mice Introduction: The metabolic effects of consuming mildly oxidized lipids as compared to highly oxidized lipids are not well documented. Consumption of highly oxidized polyunsaturated fatty acids, even in a low-fat diet, may be a threat to one’s health. Previous studies in our lab have shown that mice consuming soybean oil heated for 3 hours, compared to unheated, gain less body weight, but more fat pad mass, and 3T3-L1 adipocytes treated with soybean oil heated for ≥ 6 hours have abrogated triglyceride accumula
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2

Dingels, Nicole Katherine. "Oxidized soybean oil alters the expression of PPAR gamma and target genes in 3T3-L1 cells." Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/nutrition_theses/40.

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Background: The typical western diet contains foods with modest amounts of lipid oxidation products. Previous work by us and others have demonstrated that mildly oxidized lipids promote a gain in fat mass while highly oxidized lipids decrease fat mass in rodents and triglyceride (TAG) accumulation in 3T3-L1 cells. Adipocyte differentiation is regulated by a key nuclear transcription factor known as PPARγ. Objective: To investigate if the alterations in triglyceride accumulation in 3T3-L1 cells pretreated with oxidized soy oil are due to 1) a change in PPARg DNA interactions 2) changes in the
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Schneider, Mary Katherine. "An Oxidized Fat Containing Diet Decreases Weight Gain but Increases Adiposity in Mice Fed a Low Fat Diet." Digital Archive @ GSU, 2009. http://digitalarchive.gsu.edu/nutrition_theses/1.

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Introduction: Fast and convenience foods are abundant, relatively inexpensive, and accommodating to the fast-paced lifestyle of many Americans. One popular method of cooking used by many fast food establishments is deep-fat frying. Soybean oil is commonly used for frying and is rich in polyunsaturated fatty acids (PUFA) such as linoleic acid (LA). When soybean oil is used for deep-fat frying, LA becomes oxidized (Ox-LA). Endogenous Ox-LA has the capacity to be a ligand to peroxisome proliferator-activated receptor gamma (PPAR¥ã), a nuclear transcription factor that regulates adipocyte maturati
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4

Lao, Ying. "Chromatographic Behavior of Peptides Containing Oxidized Methionine in Reversed-phase Chromatography: Application to Cyclolinopeptides in Flaxseed Oil and Linear Tryptic Peptides." Elsevier, 2012. http://hdl.handle.net/1993/30202.

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The thesis consists of two parts targeting the characterization of chromatographic behavior of linear tryptic and cyclic peptides containing oxidized methionine (Met) in reversed-phased chromatography. The retention order of methionine-containing peptide analogues was observed to be the same in both studies: Met oxide < Met dioxide < Met. For linear tryptic peptides, the magnitude of the retention time shift may vary dramatically: from –9 % to +0.36 % acetonitrile. Particularly, large negative retention time shifts are found mostly associated with methionine being in the hydrophobic face of an
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Delles, Rebecca. "DIETARY ANTIOXIDANT SUPPLEMENTATION (ECONOMASE–BIOPLEX) TO ALLEVIATE ADVERSE IMPACTS OF OXIDIZED OIL ON BROILER MEAT QUALITY: A CHEMICAL, TEXTURAL, ENZYMATIC, AND PROTEOMIC STUDY." UKnowledge, 2013. http://uknowledge.uky.edu/animalsci_etds/29.

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This study investigated the influence of dietary antioxidants and quality of oil on the oxidative and enzymatic properties of chicken broiler meat stored in an oxygen-enriched package (HiOx: 80% O2/20% CO2) in comparison with air-permeable polyvinylchloride (PVC) or skin (SK) packaging systems during retail display 2–4 °C for up to 14, 7, and 21 d, respectively. Broilers were fed a diet either with a low-oxidized oil (peroxide vale POV 23 meq O2/kg) or with a high-oxidized oil (POV 121 meq O2/kg), supplemented with an antioxidant pack (200 ppm EconomasE and organic minerals Se, Zn, Cu, Mn, and
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6

Kim, Hyun Jung. "Oxidation mechanism of riboflavin destruction and antioxidant mechanism of tocotrienols." Columbus, Ohio : Ohio State University, 2007. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1184681773.

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7

Chen, Hongjiang. "Studies on Cell Injury Induced by Hypoxia-Reoxygenation and Oxidized Low Density Lipoprotein : With Special Reference to the Protectiove Effect of Mixed Tocopherols, Omega-3 Fatty Acids and Transforming Growth Factor-beta1." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3769.

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8

Fujioka, Kazutoshi. "Formation/inhibition and toxicity of reactive carbonyl compounds from oxidized dietary oils : antioxidant properties of phytochemicals measured by headspace solid-phase microextraction/gas chromatography /." For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2005. http://uclibs.org/PID/11984.

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9

朱哲輝. "Effects of the oxidized frying oil on the." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/38834777315956376550.

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10

Tang, Ya-Li, and 湯雅理. "Dietary Oxidized Frying Oil and Renal Prostaglandin E2 Production." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/05500706673652375423.

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博士<br>國立臺灣大學<br>農業化學研究所<br>88<br>Previously, it was shown that urinary bicyclo PGE2, the metabolite of PGE2 increased significantly in rat fed oxidized frying oil (OFO). It has also been demonstrated that an XRE element has been identified in the 5'' noncoding region of the Prostaglandin H synthase (PGHS) gene. Recently it was observed that TCDD stimulates the expression of PGHS-2 mRNA in MDCK cell line. PGHS has been suggested to be important in the extrahepatic metabolism of xenobiotics. The main aim of this study was to examine whether PGE2 production can be changed by dietary OFO and secon
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11

Liao, Chun-Huei, and 廖純慧. "Study on the glucose intolerance effect of oxidized frying oil." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/34475078450854538808.

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碩士<br>中國醫藥大學<br>營養學系碩士班<br>95<br>We had previously found that dietary oxidized frying oil (OFO)could decrease body fat and induce glucose intolerance in the rats and mice. The aim of this study was to investigate the mechanism of OFO induced glucose intolerance in mice. Experiment 1 was designed for comparing the OFO effect with the conjugated linoleic acid (CLA) induced lipodystrophy diabetes . 51 C57BL/6J mice were divided into five groups. In order to observe the lipodystrophy diabetes induced by CLA, LF and the CLA group were set, to receive a diet containing 4% (g/g) fresh soybean oil (L
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12

Chiang, Zong-Cian, and 江宗謙. "Dietary oxidized frying oil interferes with vitamin A metabolism and results in teratogegnesis." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/28178479737763146838.

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碩士<br>中國醫藥大學<br>營養學系碩士班<br>101<br>In our previous study, we had observed a higher incidence of malformations in fetuses of dams receiving oxidized frying oil (OFO) during pregnancy. It has been reported that OFO can activate the peroxisome proliferator-activated receptor alpha (PPARα). Clofibrate, as a PPARα activator, has been shown to affect expression of genes participating in retinoic acid (RA) catabolism. Being regarded as a morphogen, excess or deficiency of RA during fetus development, both result in teratogenesis. Environmental contaminants such as plasticizer (di(2-ethylhexyl) phthala
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13

Chiang, Ya-Fan, та 蔣亞帆. "Effect of Oxidized Frying Oil Consumption on Insulin Secretion by Pancreatic β-cells". Thesis, 2009. http://ndltd.ncl.edu.tw/handle/99545142340967374493.

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碩士<br>中國醫藥大學<br>營養學系碩士班<br>97<br>Being crisp and aromatic, fried foods are popular with consumers world-wide while the safety concerns about the ingestion of oxidized frying oil (OFO) are still raised. We had previously shown that OFO ingestion can influence lipid and glucose metabolism. Dietary OFO increases fatty acids oxidation in liver by activating peroxisome proliferator-activated receptor α. However, accompanied with TG reductions, glucose intolerance is observed in OFO-fed rodents. Since the serum levels of insulin and C-peptide in oral glucose tolerance test were both decreased in OFO
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14

Chen, Ming Hsiung, and 陳名雄. "Effect of taurine on toxicities of oxidized cholesterol and fish oil in rats." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/18702805469624397768.

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碩士<br>國立海洋大學<br>食品科學系<br>91<br>Cholesterol was widely distributed in foods of animal origin, however there were usually to contain high dose of cholesterol and high dose of polyunsaturated fatty acid (PUFA) in marine foods, and furthermore there were also to contain taurine. When people make use of these kinds of marine foods, the oxidation of cholesterol and oil were not usually prevented. Some cholesterol oxides could cause harmful to our physiological reaction, and oxidized oil, too. On the other hand, it has been reported that taurine improves people who had hypercholesterolemia, and it al
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15

Zhang, Lian-Yun, and 張廉筠. "The Effect of Oxidized Frying Oil on Antioxidative Status and Renal Damage in Mice." Thesis, 2009. http://ndltd.ncl.edu.tw/handle/3h2uyu.

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碩士<br>嘉南藥理科技大學<br>營養與保健科技研究所<br>97<br>Unhealthy lifestyle, dietary patterns or disease may increase risk of chronic kidney disease (CKD). The mechanism is still poorly understood whether dietary fat quantity and quality affect renal function, resulting in the occurrence of CKD. Therefore, the purpose of this study was to determine the effect of oxidized frying oil (OFO) on antioxidative status, inflammation and apoptosis-related molecules expression of kidney. This study was divided into three experiments which used five-week-old female C57BL/6 mice. The experiment A was to study the kidne
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Chao, Pei-Min, and 趙蓓敏. "Studies on the Activation of Peroxisome Proliferator-Activated Receptor alpha by Oxidized Frying Oil." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/95966034120909298262.

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博士<br>國立臺灣大學<br>農業化學研究所<br>90<br>It has been reported that rats fed an oxidized frying oil (OFO) containing diet show physiological effects like PPARalpha (peroxisome proliferator-activated receptor alpha) activation. Recently, conjugated linoleic acid (CLA), oxidized low density lipoprotein (oxLDL) and its component hydroxy fatty acids derived from linoleic acid are shown to activate PPARalpha and PPARgamma. It was hypothesized that lipid oxidation products in dietary OFO may activate PPARalpha and regulate the expression of its target genes. To test this hypothesis and, the following four ex
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17

韓良娟. "Effects of Oxidized Oil, Antioxidant and Temperature on the Growth of Japanese Eel(Anguilla Japonica)." Thesis, 1995. http://ndltd.ncl.edu.tw/handle/95994822215859037367.

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碩士<br>國立海洋大學<br>水產食品科學研究所<br>83<br>The effects of oxidized oil and BHT on the Japanese eel (Anguilla japonica) were determined. Japanese eel were treated with POV 27.7 to 97.4 meq/kg oil and 0.02% BHT in their diet for 12 weeks. The growth rate and glutathione content in liver were found to significantly decrease when Japanese eel were fed a diet with supplements of oxidized oil (POV> 50 meq/kg oil) and 0.02% BHT. The hepatosomatic index (HSI) and the level of thiobarbituric acid-reactive substances (TBARS) were found to significantly increase when Japanese eel were fed a diet with supplements
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18

Chen, Qiao Ming, and 陳巧明. "Splenocyte proliferation、prostaglandin synthesis and DMBA-induces mammary tumorigenesis in rat fed oxidized frying oil." Thesis, 1994. http://ndltd.ncl.edu.tw/handle/07691953362028886255.

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Cheng, Hsiao-Chien, and 鄭曉倩. "The Effect of Oxidized Frying Oil on Airway Inflammation of OVA-sensitized BALB/c Mice." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/16612600344475543772.

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碩士<br>國立臺灣大學<br>農業化學研究所<br>89<br>The prevalence of allergic disease has increased rapidly in the past decade. Both high fat and frying oil diets have been though to play an important role in increasing the prevalence of allergic disease. In this study, we investigated the effect of different preparations of frying oil on immune responses in murine model of airway inflammation. In the first experiment, ten-week-old male mice were randomly divided into five groups fed on diet containing either 5 % fresh soybean oil ( S5 ), 15 % fresh soybean oil ( S15 ), 15 % frying soybean oil under
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Lin, Ting-Yi, та 林庭伊. "The role of PPARα in the teratogenic effect of polar fraction in oxidized frying oil". Thesis, 2014. http://ndltd.ncl.edu.tw/handle/kj85ue.

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碩士<br>中國醫藥大學<br>營養學系碩士班<br>102<br>Deep-fried food is very popular, but the safety of oxidized frying oil (OFO) is a concern. During the deep frying process, a series of reactions occur in the frying oil, which produce the hydrolytic products and of altered TG with at least one oxygenated functional group, such as epoxides, ketones, or alcohols, on the esterified fatty acids, totally named polar (PO) fraction. PO fraction is regarded as the major deteriorate components in used oils. We have previously shown that dietary OFO, specifically the PO fraction, is teratogenic, which is attributable to
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HUANG, Shiau-Ting, and 黃曉婷. "Effect of oxidized frying oil on abdominal fat accumulation, adipocyte differentiation and insulin sensitivity of rats." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/94673217908323072579.

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碩士<br>中國醫藥大學<br>營養研究所<br>93<br>Abstract Peroxisome proliferator-activated receptor (PPAR) is a member of steroid hormone receptor superfamily of ligand-activated transcription factors. To date, three isoforms have been identified, PPARa, d and g, encoded by three separate genes. PPARa is expressed predominantly in lipid metabolizing tissue, such as liver where it plays a role in lipid catabolism. PPARg, on the other hand, is mainly expressed in adipose tissue and has a critical role in adipocyte differentiation and glucose metabolism. We had previously proved that dietary fish oil and oxidized
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Wu, Hai-Ping, and 吳海平. "Effect of oxidized frying oil-containing diet on development of male reproductive system in SD rats." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/y2xphp.

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Chang, Ya-Fen, and 鄭雅分. "Effect of purple sweet potato leaf on the colorectal carcinogenesis of oxidized frying oil-fed F344 rats." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/13654701762194088687.

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碩士<br>臺北醫學大學<br>保健營養學系<br>93<br>The aim of this study was to investigate the effect of purple sweet potato leaf and oxidized frying oil (OFO) on colorectal carcinoma of F344 rats treated with DMH (1,2-dimethylhydrazine). Twenty-seven male F344 rats received 30mg/kg body weight DMH by intraperitoneal injection, once weekly for 6 weeks. Vehicle-treated groups received an equal volume of normal saline. Rats were assigned to 6 groups which diets containing 20% fresh soybean oil (FO): FS0 and FD0, 20% OFO: OS0 and OD0, 20% OFO with 2.5% purple sweet potato leaf: OS2.5 and OD2.5. Rats were sacrifi
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Chuang, Hui-Ching, and 莊蕙璟. "The metabolic programming effect on offspring of mothers receiving an oxidized frying oil-containing diet during pregnancy." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/43077850944779907771.

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碩士<br>中國醫藥大學<br>營養學系碩士班<br>99<br>More recently, epidemiological and experimental evidences suggest that the nutrient state in embryonic period is closely associated with adulthood obesity and metabolic syndrome, giving rise to the concept of “metabolic programming”. Since it has been reported that the oxidized frying oil (OFO) consumption in animals results in growth retardation and nutrients depletion, we hypothesized that OFO consumption of female mice during pregnancy might compromise the fetus development in uterus and increase the suceptibility of their offspring to high fat diet-induced
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侯嘉玲. "Effect of taurine on the toxicity of oxidized oil and excess dose of vitamin A in rats." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/38327498138834043181.

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Mou, Tsung-Yi, and 牟宗宜. "The effect of oxidized frying oil and vitamin E on immune response of OVA-sensitized BALB/c mice." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/98913571419855474594.

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Huang, Wen-chi, and 黃玟綺. "Effect of Oxidized Frying Oil on the Expression of Proteins and Genes Relative to Vitamin EMetabolism in Rats." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/82916999447653328164.

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碩士<br>嘉南藥理科技大學<br>營養與保健科技研究所<br>96<br>Vitamin E is the most important lipid-soluble antioxidant in the body . The previous study showed that the retention of dietary vitamin E in rat tissues was affected by dietary frying oil , but the mechanism is still unclear . The purpose of this study is to investigate the effects of oxidized frying oil on the expression of protein and genes relative to vitamin E metabolism in rat liver. In experiment 1 , three groups of male Wistar weanling rats were fed the control diet (CO , containing 15% fresh soyben oil ) or test diets (FO and FOE , containing 15% f
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Li, Ai Fen, and 李艾芬. "Estrogen biosynthesis in cultured rat ovarian granulosa cells is enhanced by serum of rat fed oxidized frying oil diet." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/83091721205900778865.

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Huang, Chin-Fang, and 黃勤方. "The teratogenic and metabolic programming effects on offspring of mothers receiving an oxidized frying oil-containing diet during pregnancy." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/30449298639703334812.

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碩士<br>中國醫藥大學<br>營養學系碩士班<br>100<br>Maternal nutrition during pregnancy affects embryonic development and also permanently alter metabolic functions of offspring in adulthood. It has been reported that consumption of oxidized frying oil (OFO) can modulate lipid metabolism through acativation of peroxisome proliferator-activated receptor alpha (PPARα). By increasing the expression of PPARα target genes, including acyl-Co A oxidase (ACO) and cytochrome P450 family 4A10 (CYP4A10), the OFO diet up-regulates fatty acid β-oxidation. In our previous study, a higher incidence of dystocia and pups-eaten
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Cheng, Wei-yi, and 鄭瑋宜. "The Effect of Dietary Oxidized Frying Oil on the Balance of Sodium and Potassium and the Production of Prostaglandin E2." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/94452861822124756184.

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碩士<br>國立臺灣大學<br>農業化學研究所<br>89<br>Prostaglandins are a lipid-derived mediator, that may exert a great variety of diverse functions, such as: stimulating smooth muscle contraction, inhibiting gastric acid secretion, enhancing platelet aggregation and vasodilation, etc. Cyclooxygenase (COX) is the key enzyme which catalyzes the first two steps in the biosynthesis of prostaglandins E2 (PGE2) from arachidonic acid. Previously, it was shown that urinary PGE2 and bicyclo PGE2, the metabolite of PGE2, increased significantly in rats fed oxidized frying oil (OFO). OFO also enhanced the PGE2 levels in t
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Yang, Ming-Tse, and 楊明澤. "Study of effects of Piper betle extracts on aortic vascular tissue in rats model fed with thermally oxidized soybean oil." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/44885449324084246567.

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碩士<br>中山醫學大學<br>生化微生物免疫研究所<br>104<br>Thermal oxidative oil, especially repeatedly used frying oil, has been implicated in several pathological processes including hypertension, fatty liver, cardiovascular disease. The studies of Piper betel L. (PBL) have confirmed its antioxidant, anticancer, anti-free radicals, anti-inflammatory, and hepatoprotective effects. Therefore, the integration of PBL extracts into daily diet would be beneficial to our life. The aim of the present study is to investigate the effects of PBL extracts on the aortic vascular tissue using a rat model feeding with thermally
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Su, Su-Hui, and 蘇素慧. "Effects of Vitamin E and Moringa leaves on the Symptoms of DSS-induced Colitis in Oxidized Frying Oil fed Mice." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/59352559206679433272.

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碩士<br>嘉南藥理科技大學<br>營養與保健科技研究所<br>98<br>Oxidized frying oil (OFO) diet has been reported to induce an increase in lipid per-oxidation and a reduction in vitamin E status in animal tissues. Our preliminary results showed that OFO-fed mice were more susceptible to DSS (dextran sulfate sodium)-induced colitis. We chose vitamin E and moringa leaves to test the ameliorative effects about deleterious process induced by OFO. The purpose of this study was to investigate the effects of vitamin E and moringa leaves supplementations on the symptoms of DSS-induced colitis in OFO-fed mice. Forty of femal
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陳雅妍. "The effects of Houttuynia cordata thunb on xenobiotic metabolizing enzymes and its antioxidative and antimutagenic ability in oxidized frying oil-fed rats." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/07399317454239518524.

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Zogona, Daniel, and 左格拿. "Effect of purple sweet potato leaves on hepatic xenobiotic-metabolizing enzymes and oxidative stress in rats fed an oxidized frying oil diet." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/5u2bj5.

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Liao, Yu-Chen, and 廖宇晨. "Study of effects of Piper betle on serum lipids, liver function & aorta in rats fed with thermally oxidized soybean oil/high-cholesterol diets." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/81965034593647865554.

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碩士<br>中山醫學大學<br>生化暨生物科技研究所<br>102<br>Thermally oxidized oil generates reactive oxygen species that have been implicated in several pathological processes including hypertension, fatty liver, cardiovascular disease. For Piper betel L. (PBL) studies, has been confirmed to have antioxidant, hepatoprotective effect. Study of effects of PBL on serum lipids, liver function & aorta in rats fed with thermally oxidized soybean oil/ high-cholesterol diets. Male Sprague-Dawley rats were divided into four groups and were fed with the following diets, respectively, for 10 weeks: basal diet (control); Unuse
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Chiang, Yu-Feng, and 江毓鳳. "Study of effects of Piper betle on serum lipids, liver function & gut microbiota in rats fed with thermally oxidized soybean oil/high-cholesterol diets." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/91371757082414512281.

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碩士<br>中山醫學大學<br>生化暨生物科技研究所<br>103<br>Thermal oxidative oil, especially repeatedly used frying oil, contains free fatty acids, small molecular alcohol, aldehyde, ketone, acid, lactone and hydrocarbon, diglyceride and monoglyceride, cyclic and epoxy compounds, trans isomers those are resulted from the chemical reactions of hydrolysis, oxidation, isomerization and polymerization during deep frying. Thermally oxidized oil generates reactive oxygen species that have been implicated in several pathological processes including hypertension, fatty liver, cardiovascular disease. Piper betel has been co
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