Academic literature on the topic 'Oxindoles'
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Journal articles on the topic "Oxindoles"
Ziarani, Ghodsi Mohammadi, Fatemeh Javadi, and Fatemeh Mohajer. "The Molecular Diversity Scope of Oxindole Derivatives in Organic Synthesis." Current Organic Chemistry 25, no. 7 (2021): 779–818. http://dx.doi.org/10.2174/1385272825666210111112814.
Full textLingam, Kandapalam, Kodirajan Selvakumar, Periyasamy Amutha, and Paneerselvam Yuvaraj. "Controlled and Efficient Stereoselective Synthesis of Oxindole-Appended 1-Aza-1,3-butadiene Derivatives via a One-Pot Buchwald–Hartwig Amination/Elimination Strategy." Synthesis 50, no. 03 (2017): 599–606. http://dx.doi.org/10.1055/s-0036-1591493.
Full textChen, Bo, Jiaheng Lei, and Junling Zhao. "Michael Addition of Aryl Thiols to 3-(2,2,2-Trifluoroethylidene)Oxindoles under Catalyst-Free Conditions: The Rapid Synthesis of Sulfur-Containing Oxindole Derivatives." Journal of Chemical Research 42, no. 4 (2018): 210–14. http://dx.doi.org/10.3184/174751918x15240724383170.
Full textOrtega-Martínez, Aitor, Cynthia Molina, Cristina Moreno-Cabrerizo, José Sansano, and Carmen Nájera. "Synthesis of 3,3-Disubstituted 2-Oxindoles by Deacylative Alkylation of 3-Acetyl-2-oxindoles." Synthesis 49, no. 23 (2017): 5203–10. http://dx.doi.org/10.1055/s-0036-1590880.
Full textJackson, Mark, Calvin Quince O'Broin, Helge Müller-Bunz та Patrick J. Guiry. "Enantioselective synthesis of sterically hindered α-allyl–α-aryl oxindoles via palladium-catalysed decarboxylative asymmetric allylic alkylation". Organic & Biomolecular Chemistry 15, № 38 (2017): 8166–78. http://dx.doi.org/10.1039/c7ob02161e.
Full textJiang, Yan, Min-Yi Tian, Xiong-Li Liu та ін. "Highly Diastereo-, α-Regioselective Catalyst-Free Construction of Adjacent Dispirobisoxindoles with Three Contiguous Quaternary Carbon Centers". Synthesis 51, № 03 (2018): 683–92. http://dx.doi.org/10.1055/s-0037-1610290.
Full textCong, Tiantian, Huamin Wang, Xiuzheng Li, Hai-Hong Wu, and Junliang Zhang. "Chiral bifunctional bisphosphine enabled enantioselective tandem Michael addition of tryptamine-derived oxindoles to ynones." Chemical Communications 55, no. 62 (2019): 9176–79. http://dx.doi.org/10.1039/c9cc04357h.
Full textDalpozzo, Renato, and Raffaella Mancuso. "Enantioselective Vinylogous Reactions of 3-Alkylidene Oxindoles." Synthesis 50, no. 13 (2018): 2463–72. http://dx.doi.org/10.1055/s-0037-1609731.
Full textTiwari, Keshri Nath, and Chandran R. "Krapcho Dealkoxycarbonylation Strategy of Ethyl Cyanoacetate for the Synthesis of 3-Hydroxy-3-cyanomethyl-2-oxindoles and 3,3′-Dicyanomethyl-2-oxindoles in a Reaction with Isatin." Synthesis 52, no. 15 (2020): 2233–40. http://dx.doi.org/10.1055/s-0040-1707816.
Full textCui, Hao, Ke Li, Yue Wang, et al. "Copper(i)/Ganphos catalysis: enantioselective synthesis of diverse spirooxindoles using iminoesters and alkyl substituted methyleneindolinones." Organic & Biomolecular Chemistry 18, no. 19 (2020): 3740–46. http://dx.doi.org/10.1039/d0ob00546k.
Full textDissertations / Theses on the topic "Oxindoles"
Edeson, Steven. "Synthesis and reactions of novel oxindoles." Thesis, University of Sheffield, 2015. http://etheses.whiterose.ac.uk/12114/.
Full textRichmond, Edward. "An asymmetric pericyclic cascade approach to oxindoles." Thesis, University of St Andrews, 2014. http://hdl.handle.net/10023/4459.
Full textElderwish, Sabria. "Synthèse de spiro-oxindoles ligands des prohibitines." Thesis, Strasbourg, 2019. http://www.theses.fr/2019STRAF019.
Full textThe scaffold proteins prohibitins-1 and 2 (PHB1/2) play many important roles in coordinating many cell signaling pathways and represent emerging targets in cardiology and oncology. The investigation of the diverse physiological roles of PHBs is hampered by the complexity of their various post-translational modifications and also by the lethality consecutive to their genetic inactivation.We report herein two convenient and robust syntheses of the new PHB ligand 2'-phenylpyrrolidinyl-spirooxindole and its analogs. We identified some analogs that protect cardiomyocytes against the toxicity induced by doxorubicin and identified the structural requirements for this activity. We also synthesized some tools that were used to find that both PHB1 and PHB2 are targeted by these spirooxindoles. Such compounds may be used as pharmacological probes to explore the role of PHBs and may provide the basis for the development of new drugs candidates to treat cardiac diseases or cancers
Molina, Cynthia. "Síntesis de 2-oxindoles 3,3-disustituidos por alquilación desacilativa." Doctoral thesis, Universidad de Alicante, 2020. http://hdl.handle.net/10045/109416.
Full textRepasky, Paul J. "Novel Trisubstituted Arylidene Oxindoles with Potent Anti-Apoptotic Properties." Wright State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=wright1310326721.
Full textTercel, Moana. "New routes to spiro-oxindoles for the synthesis of gelsemine." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317870.
Full textKnisley, Kyle James. "Libraries from Libraries Approach to the Synthesis of Arylidene Oxindoles." Wright State University / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=wright1388766101.
Full textBelletti, Giada. "Organocatalytic Enantioselective Vinylogous Aldol-Lactonization Cascade Reaction of 3-Alkylidene Oxindoles to Trifluoromethyl Ketones." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amslaurea.unibo.it/14463/.
Full textToyoshima, Takeharu. "Synthesis of Oxindoles by Palladium Catalyzed Cyclization Reactions of 2-(Alkynyl)aryl Isocyanates with Nucleophiles." 京都大学 (Kyoto University), 2011. http://hdl.handle.net/2433/142568.
Full textRousseau, Géraldine. "Synthèse et désymétrisation d'arylcyclohexa-2,5-diènes : application à la synthèse totale de l'épi-Elwesine." Thesis, Bordeaux 1, 2008. http://www.theses.fr/2008BOR13654/document.
Full textThe desymmetrization of arylcyclohexa-2,5-dienes is a powerful method to synthesize complex structures from simple synthons in a single step. We first developed a new protocol to obtain arylcyclohexa-2,5-dienes bearing a quaternary center. One of these structures was desymmetrized via a diastereoselective hydroamination and further elaborated into epi-Elwesine, an Amaryllidaceae alkaloid. We next turned our attention towards the synthesis and desymmetrization of spirocyclic cyclohexadienes. Diastereoselective processes were carried out due to the presence of two well- differentiated faces. A new rearrangement-alkylation process was developed and provides efficient access to phenanthridinones regio- and diastereoselectively
Books on the topic "Oxindoles"
Rafipoor, Fereshteh. Synthesis of oxindole quionones and carboline quinones. Brunel University, 1991.
Book chapters on the topic "Oxindoles"
Russel, Jonathon S. "Oxindoles and Spirocyclic Variations: Strategies for C3 Functionalization." In Topics in Heterocyclic Chemistry. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/7081_2010_50.
Full textDi Iorio, Nicola. "The Vinylogous Reactivity of Oxindoles Bearing Non-symmetric 3-Alkylidene Groups." In Springer Theses. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-74914-3_2.
Full textReinecke, D. "The Oxindole-3-Acetic Acid Pathway in Zea mays." In Plant Growth Substances 1988. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74545-4_43.
Full textMoroni, Flavio, Raffaella Carpenedo, Guido Mannaioni, et al. "Studies on the Pharmacological Properties of Oxindole (2-Hydroxyindole) and 5-Hydroxyindole: Are They Involved in Hepatic Encephalopathy?" In Advances in Experimental Medicine and Biology. Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5945-0_4.
Full text"Oxindoles." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_12071.
Full textBergman, Jan. "Oxindoles." In Advances in Heterocyclic Chemistry. Elsevier, 2015. http://dx.doi.org/10.1016/bs.aihch.2015.08.001.
Full textDeRosa, Thomas F. "Aza-Oxindoles." In Advances in Synthetic Organic Chemistry and Methods Reported in US Patents. Elsevier, 2006. http://dx.doi.org/10.1016/b978-008044474-1/50015-3.
Full text"3-Hetero-3-Substituted Oxindoles." In Asymmetric Synthesis of 3,3-Disubstituted Oxindoles. WORLD SCIENTIFIC (EUROPE), 2019. http://dx.doi.org/10.1142/9781786347305_0006.
Full textHof, K., K. M. Lippert, and P. R. Schreiner. "Michael Addition of Oxindoles to Maleimides." In Brønsted Base and Acid Catalysts, and Additional Topics. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-205-00219.
Full textHof, K., K. M. Lippert, and P. R. Schreiner. "Mannich Reaction of Oxindoles with Imines." In Brønsted Base and Acid Catalysts, and Additional Topics. Georg Thieme Verlag KG, 2012. http://dx.doi.org/10.1055/sos-sd-205-00234.
Full textConference papers on the topic "Oxindoles"
Santos, Maria, Elizabeth Lopes, Margarida Espadinha, Mattia Mori, and Maurizio Botta. "Enhancing anticancer activity of spiropyrazoline oxindoles by disrupting p53-MDMs PPIs." In 5th International Electronic Conference on Medicinal Chemistry. MDPI, 2019. http://dx.doi.org/10.3390/ecmc2019-06352.
Full textMacaev, Fliur. "Molecular architecture of chiral oxindoles as a facile platform to new drug candidates." In New frontiers in natural product chemistry, scientific seminar with international participation. Institute of Chemistry, 2021. http://dx.doi.org/10.19261/nfnpc.2021.ab09.
Full textMarini, Francesca, Luca Rossi, Luca Sancineto, Luana Bagnoli, and Claudio Santi. "Michael Initiated Ring Closure Reactions in Aqueous Medium for the Synthesis of Spiro Cyclopropyl Oxindoles." In The 18th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2014. http://dx.doi.org/10.3390/ecsoc-18-a020.
Full textMatheson, Christopher J., Kimberly A. Casalvieri, Donald S. Backos, Craig T. Jordan, and Philip Reigan. "Abstract C078: Substituted oxindoles as AMP-activated protein kinase (AMPK) inhibitors and their evaluation in models of leukemia." In Abstracts: AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics; October 26-30, 2019; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1535-7163.targ-19-c078.
Full textMaldonado Rivera, José Luis, E. Pérez-Gutiérrez, M. Rodríguez, et al. "OLEDs fabricated by solution process based on a novel linear poly(arylene oxindole)." In Organic Light Emitting Materials and Devices XXII, edited by Franky So, Chihaya Adachi, and Jang-Joo Kim. SPIE, 2018. http://dx.doi.org/10.1117/12.2322752.
Full textPireddu, Roberta, Harshani R. Lawrence, Mathew P. Martin, et al. "Abstract 3253: Novel oxindole inhibitors of Aurora A kinase: Structure based hit-to-lead approach." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3253.
Full textDelaisi, Christine, Isabelle Meaux, Odette Dos-Santos, et al. "Abstract 4648: In vitro characterization of spiro-oxindole-based modulators of the MDM2-p53 interaction and their interspecies selectivity." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-4648.
Full textMeaux, Isabelle, Cédric Barrière, Donna McEachern, et al. "Abstract 4731: Cytotoxic versus cytostatic effects in tumor models by spiro-oxindole-based modulators of the MDM2-p53 interaction." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-4731.
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