Relevant bibliographies by topics / Oxopyrazoles

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  1. Journal articles
  2. Dissertations / Theses

Academic literature on the topic 'Oxopyrazoles'

Author: Grafiati
Published: 5 June 2025
Last updated: 1 August 2025

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Journal articles on the topic "Oxopyrazoles"

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Azev, Yurii A., Irina V. Teplyashina, and Sergei V. Shorshnev. "Unusual reactions of enhydrazinopyrazolones and dipyrazolylmethanes with 5-oxopyrazoles." Mendeleev Communications 8, no. 5 (1998): 199–200. http://dx.doi.org/10.1070/mc1998v008n05abeh001010.

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Azev, Yurii A., Irina V. Teplyashina, and Sergei V. Shorshnev. "ChemInform Abstract: Unusual Reactions of Enhydrazinopyrazolones and Dipyrazolylmethanes with 5-Oxopyrazoles." ChemInform 30, no. 9 (2010): no. http://dx.doi.org/10.1002/chin.199909140.

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M., B. HOGALE, and N. PAWAR B. "Synthesis and Biological Activity of N1 -Substltuted-3-methyl-5-pyrazolones and related Compounds." Journal of Indian Chemical Society Vol. 66, Feb 1989 (1989): 135–38. https://doi.org/10.5281/zenodo.6303570.

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Department of Chemistry, Shivaji University, Kolhapur-416 004 <em>Manuscript received 2</em>4 J<em>une 1988 revised 14 October 1988,&nbsp;accepted 18 November 1988</em> Synthesis and Biological Activity of N<sub>1</sub> -Substltuted-3-methyl-5-pyrazolones and related Compounds&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;
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Babadeev, D. V., and E. A. Stroganova. "Synthesis and identification of 1,1,3,3-tetra-[1,2-dihydro-1,5-dimethyl-2-phenyl-3-oxopyrazole]propane." Proceedings of Universities. Applied Chemistry and Biotechnology 10, no. 3 (2020): 386–92. http://dx.doi.org/10.21285/2227-2925-2020-10-3-386-392.

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Pyrazole derivatives are of practical value as analytical reagents, dyes and medicinal substances. It is known that 1,2-dihydro-1,5-dimethyl-2-phenylpyrazol-3H-one (antipyrine) and its bidentate derivatives are good analytical reagents for d-metal ions (Cd2+, Fe3+, Sc3+, Ti4+, Zn2+, Co2+, etc.). The chelating ability of bi-, tri- and tetradentate antipyrine derivatives make them promising organic ligands for the synthesis of organometallic coordination polymers. Therefore, synthesis of new tetradentate derivatives of 1,2-dihydro-1,5-dimethyl-2-phenyl-3Hpyrazole-one seems to be a highly relevan
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Goldberg, Joel, Christopher Bethel, Andrea M. Hujer, et al. "698. In vitro Activity of a New Generation Oxopyrazole Antibiotic Against Multidrug-Resistant Gram-Negative Bacilli." Open Forum Infectious Diseases 6, Supplement_2 (2019): S315—S316. http://dx.doi.org/10.1093/ofid/ofz360.766.

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Abstract Background Multidrug-resistant Gram-negative bacilli (MDRGNB) are emerging as a challenging cause of hospital-acquired infections and represent a critical need for innovative antibacterial development. New oxopyrazole agents targeting penicillin-binding proteins (PBPs) based on a non-β-lactam core and incorporating a siderophore moiety (Figure 1) which facilitates transport to the periplasm are being developed that show promise against Gram-negative organisms including multidrug-resistant strains of E. coli, K. pneumoniae and P. aeruginosa. Methods YU253434, an example of this new cla
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Mugnaini, Claudia, Magdalena Kostrzewa, Marta Casini, et al. "Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affinity and Selectivity for the Cannabinoid Type 2 Receptor." Molecules 28, no. 13 (2023): 4958. http://dx.doi.org/10.3390/molecules28134958.

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Selective ligands of the CB2 receptor are receiving considerable attention due to their potential as therapeutic agents for a variety of diseases. Recently, 7-hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide derivatives were shown to act at the CB2 receptor either as agonists or as inverse agonists/antagonists in vitro and to have anti-osteoarthritic activity in vivo. In this article, we report the synthesis, pharmacological profile, and molecular modeling of a series of twenty-three new 7-hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamides with the aim of further developing this new class o
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Schmidt, Arthur H., Timo Schreck, Ralf Rötz, and Sarah von Freytag-Loringhoven. "Oxokohlenstoffe und verwandte Verbindungen, 30 [1]. Über die Umsetzung von Quadratsäure mit Pyrazolinonen / Oxocarbons and Related Compounds, 30 [1]. On the Reaction of Squaric Acid with Pyrazolinones." Zeitschrift für Naturforschung B 61, no. 3 (2006): 311–19. http://dx.doi.org/10.1515/znb-2006-0311.

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Abstract Heating of squaric acid (1) with the 1-aryl-3-methyl-5-oxo-2,5-dihydro-1H-pyrazoles 3a - j and the 1,3-disubstituted pyrazolinones 7a - d in the molar ratio of 1:2 in a mixture of n-BuOH/toluene afforded the bis(pyrazolyl)-squaraines 4a - j and 8a - d, respectively. Reaction of an excess of 1 with the pyrazolinone 3j yielded 4j and the 3-hydroxy-4-pyrazolyl-cyclobutene-1,2-dione 6 as a byproduct. In contrast to disubstituted pyrazolinones, the trisubstituted pyrazolinones 9a - e reacted with squaric acid (1) to give the hydroxy-oxopyrazolyl-cyclobutenediones 10a - e.
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8

Goldberg, Joel, Christopher Bethel, Andrea M. Hujer, et al. "687. In vitro Activity of a New Generation Oxopyrazole Antibiotic Against Acinetobacter spp." Open Forum Infectious Diseases 6, Supplement_2 (2019): S312. http://dx.doi.org/10.1093/ofid/ofz360.755.

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Abstract Background Acinetobacter spp. resistant to common antibiotics have become a worrying cause of hospital-acquired infections and represent a critical need for innovative antibacterial development. New oxopyrazole agents targeting penicillin-binding proteins (PBPs) based on a non-β-lactam core and incorporating a siderophore moiety (figure) which facilitates transport to the periplasm are being developed which show promise against Gram-negative organisms including Acinetobacter spp. Methods YU253911, an example of this new class of antibacterials, was characterized in vitro. Minimum inhi
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Chernyshev, V. V., A. V. Yatsenko, V. A. Tafeenko, E. J. Sonneveld, H. Schenk, and V. A. Makarov. "Crystal and molecular structure of 1-amino-4-methoxycarbonyl-3-methyl-8-oxopyrazolo[1,5-a]pyrimidine monohydrate from laboratory powder data." Powder Diffraction 14, no. 4 (1999): 289–92. http://dx.doi.org/10.1017/s0885715600010708.

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The crystal structure of 1-amino-4-methoxycarbonyl-3-methyl-8-oxopyrazolo[1,5-a]pyrimidine monohydrate, C9H10N4O3·H2O, from the family of pyrazolo[1,5-a]pyrimidines which demonstrate an activity against the influenzavirus A and coxsackievirus B3, has been determined from laboratory (Guinier-Johannson photograph) powder diffraction data using a grid search procedure. Parameters of the monoclinic cell (P21/a, No. 14, Z=4) at 295 K are a=11.599(7) Å, b=11.550(7) Å, c=8.575(5) Å, β=110.76(4)°. Rietveld refinement (full-pattern-decomposition) gave χ2=4.8(4.5), Rp=0.048(0.043), Rwp=0.065(0.062). The
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YOSHITAKE, Yasuyuki, Masashi ETO, and Kazunobu HARANO. "Crystallographic and Molecular Orbital Studies of 4-Oxopyrazole 1,2-Dioxides. An Exceptionally Elongated N-N Bond." CHEMICAL & PHARMACEUTICAL BULLETIN 47, no. 5 (1999): 601–6. http://dx.doi.org/10.1248/cpb.47.601.

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Dissertations / Theses on the topic "Oxopyrazoles"

1

Huang, Li-Jiau, and 黃麗嬌. "Synthesis and Biological Activity of Condensed 5-Oxopyrazoles." Thesis, 1993. http://ndltd.ncl.edu.tw/handle/54793172963968358617.

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博士<br>中國醫藥學院<br>藥物化學研究所<br>81<br>As a result of our continuing study aimed at the search and development of novel antiplatelet agents, the lead compounds, 3, 4-dimethylpyrano[2,3-c]pyrazol-6-one(Ⅸ) and 2-benzyl-3,4- dimethyl-furo[2,3-c]pyrazole-5-carboxylic acid(ⅩⅩⅤ6) were synthesized and found to possess interesting antiplatelet antivity. Encouraged by this preliminary result, a synthetic investigation on the N-arylmethylpyrano[2,3-c]pyrazol-6-ones(Ⅹ, ⅩⅠ), N-arylmethylfuro[2,3-c]pyrazole-5
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