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Dissertations / Theses on the topic 'Oxygen'

Author: Grafiati

Published: 4 June 2021

Last updated: 25 July 2025

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1

González-Posada, Alba. "Biological oxygen production from oxygen-to-argon ratios and oxygen isotopologues in the Atlantic Ocean." Thesis, University of East Anglia, 2012. https://ueaeprints.uea.ac.uk/48046/.

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Marine primary producers play an important role in controlling the atmospheric carbon dioxide through photosynthesis and export of organic matter into the deep ocean. In this thesis I used two biogeochemical techniques based on O2/Ar ratios and O2 isotopologues to measure net community production (N) and gross oxygen production (G) in two different areas relevant for the marine C cycle: the South Atlantic subtropical gyre and the North Atlantic during a spring bloom. The former despite small rates of production it is relevant for the global marine C cycle due to the large area it covers; in ad

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2

MacPherson, Tara A. "Sediment oxygen demand and biochemical oxygen demand : patterns of oxygen depletion in tidal creek sites /." Electronic version (PDF), 2003. http://dl.uncw.edu/etd/2003/macphersont/taramacpherson.pdf.

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3

Fried, Stephen D. (Stephen David) 1987. "Oxygen-oxygen bonds : catalytic redox pathways in energy storage." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/49754.

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Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2009.<br>Vita.<br>Includes bibliographical references.<br>Introduction: The present understanding of energy - its many forms, and its governing role in the time evolution of physical systems - underlies many of the most fundamental and unifying principles furnished by scientific theories. We are now deeply aware that energy is inherently quantized and is associated with stationary states (from quantum theory), that it is conserved (from the first law of thermodynamics), but that its conversion is asymmetric and not invar

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4

Martin, Manfred. "Oxygen and cation diffusion processes in oxygen ion conductors." Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-193656.

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We discuss oxygen and cation diffusion processes in oxygen ion conductors. While the high oxygen diffusivity determines the proper oxygen ion conductivity, slow cation diffusion processes are important for sintering and degradation processes. In the first part of the paper we discuss an analytical model for the ionic conductivity of a strongly acceptor doped, fluorite-type oxygen ion conductor, i.e. a concentrated solution of AO2 and BB2O3. The model can be applied, e.g., to yttria doped zirconia (YSZ) and gives a qualitative explanation of the observed maximum of the conductivity as a functio

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5

Martin, Manfred. "Oxygen and cation diffusion processes in oxygen ion conductors." Diffusion fundamentals 6 (2007) 39, S. 1-16, 2007. https://ul.qucosa.de/id/qucosa%3A14216.

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We discuss oxygen and cation diffusion processes in oxygen ion conductors. While the high oxygen diffusivity determines the proper oxygen ion conductivity, slow cation diffusion processes are important for sintering and degradation processes. In the first part of the paper we discuss an analytical model for the ionic conductivity of a strongly acceptor doped, fluorite-type oxygen ion conductor, i.e. a concentrated solution of AO2 and BB2O3. The model can be applied, e.g., to yttria doped zirconia (YSZ) and gives a qualitative explanation of the observed maximum of the conductivity as a functio

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6

Li, Chao. "Developing Oxygen-sensitive Probes for Long-term Oxygen Monitoring." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1532101587783144.

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7

Kwabi, David G. (David Gator). "Electrochemical studies of oxygen reduction for aprotic lithium-oxygen batteries." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/104238.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2016.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 166-175).<br>Understanding oxygen electrochemistry lies at the heart of enabling many advanced energy storage and conversion technologies such as fuel cells, electrolyzers and metal-air batteries. Aprotic Li-02 electrochemistry is receiving much attention in this regard, as the Li-0 2 battery theoretically offers higher energy densities than conventional Li-ion systems at potentially lower cost. This thesis exp

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8

Christensen, P. A. "Oxygen-evolving photosystems." Thesis, Imperial College London, 1986. http://hdl.handle.net/10044/1/37971.

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9

Li, Jia. "Oxygen consumption and oxygen delivery in children after cardiopulmonary bypass surgery." Thesis, Imperial College London, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.406548.

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10

Kay), Thomas Julie K. (Julie. "Oxygen ion conduction in layered intergrowth structures with intrinsic oxygen vacancies." Thesis, Massachusetts Institute of Technology, 1994. http://hdl.handle.net/1721.1/17392.

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11

Low, Clarke Alan. "Transient oxygen consumption rate measurements with the BDT̳M̳ oxygen biosensor system." Thesis, Massachusetts Institute of Technology, 2008. http://hdl.handle.net/1721.1/45922.

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Thesis (S. M.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 2008.<br>In title on title page, double-underscored "TM" appears as superscript .<br>Includes bibliographical references (p. 109-111).<br>Oxygen consumption rate (OCR) is a reliable indicator of tissue health. Recently, the OCR of isolated human islets has been shown to predict transplant outcome in diabetic mice. The Oxygen Biosensor System (OBS) is a high-throughput, convenient assay that indirectly measures oxygen consumption by measuring oxygen partial pressure, pO2, adjacent to tissue loaded into the OBS

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12

Landon, James R. "Electrochemical Oxygen Production: Catalyst Development to Meet the World’s Oxygen Demands." Research Showcase @ CMU, 2011. http://repository.cmu.edu/dissertations/557.

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13

YANG, ZHAOHUI. "HIGH TEMPERATURE OXYGEN SORPTION PROCESS FOR AIR SEPARATION AND OXYGEN REMOVAL." University of Cincinnati / OhioLINK, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1028824899.

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14

Gilmore, Paul. "Regulation of Oxygen Transport in Potassium-Oxygen Batteries Using Conducting Polymers." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1555588196317105.

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15

Hahn, Johannes [Verfasser]. "Oxygen Variability and Eddy-driven Meridional Oxygen Supply in the Tropical North East Atlantic Oxygen Minimum Zone / Johannes Hahn." Kiel : Universitätsbibliothek Kiel, 2013. http://d-nb.info/1035637774/34.

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16

Manfredi, Gabriele. "Oxygen sensors and electrochemical oxygen pumps for lead alloy cooled nuclear systems." Doctoral thesis, Universite Libre de Bruxelles, 2018. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/267601.

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MYRRHA, a Multi-purpose hYbrid Research Reactor for High-tech Applications is currently under development at the Belgian nuclear research center SCK•CEN. It is the first prototype of a nuclear reactor driven by a particle accelerator in the world. Lead-Bismuth Eutectic (LBE) has been selected as spallation neutron source and as primary reactor coolant. Oxygen control strategy has been defined to mitigate undesirable liquid metal corrosion occurring between the steel surface of the main components of MYRRHA and the LBE itself. The development of a reliable oxygen sensor and control device beyon

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17

Leung, Ricky. "Enhancement of oxygen transfer rate using microencapsulated silicone oils as oxygen carriers." Thesis, McGill University, 1992. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=56795.

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Silicone oils were microencapsulated within polyamide (nylon) membranes cross-linked with polyethylenimine. Solubility of oxygen within the silicone oils, whether encapsulated or not, was approximately 6 mM, representing solubilities 20 fold higher than that of oxygen in water. Assuming that the bioreactor volume consists of 10 to 20% microencapsulated silicone oil, this represents an enhancement of the oxygen reservoir by a factor ranging from 4 to 7. The use of 20%(v/v) microcapsule dispersions also enabled a 4 to 5 times increase of volumetric oxygen transfer coefficient (k$ sb{ rm L}$a), c

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18

Davies, H. L. "Catalysts for oxygen evolution." Thesis, Swansea University, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.636367.

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The efficiency of photochemical systems for water cleavage into hydrogen and oxygen depends on the discovery of suitable catalysts for the reduction and oxidation reactions. The most widely studied oxygen catalytic material has been ruthenium dioxide hydrate; however, its activity depends on its degree of hydration. Highly hydrated ruthenium dioxide (RuO<SUB>2</SUB>.xH<SUB>2</SUB>O) is a poor O<SUB>2</SUB> catalyst and readily corrodes to RuO<SUB>4</SUB> in the presence of a strong oxidant. Few kinetic studies have been carried out on the dissolution of powder suspensions by various oxidants b

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19

Gara, Matthew. "Oxygen reduction on platinum." Thesis, University of Oxford, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.665289.

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Proton exchange membrane (PEM) fuel cells have the potential to provide a clean and convenient source of power for applications such as vehicle transport. At their heart lies a platinum catalyst which is used to reduce oxygen to water. Although platinum is expensive it is the best elemental catalyst for the reaction. In order to make better use of the platinum and reduce production costs, nanoparticulate platinum is dispersed onto a carbon support. This results in a greater surface area per gram of platinum used. Efforts to improve the performance of fuel cells and make them cost effective hav

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20

Bedford, Simon Bernard. "Synthesis of oxygen heterocycles." Thesis, University of Nottingham, 1993. http://eprints.nottingham.ac.uk/13159/.

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In chapter one, the various methods of generating benzenoid orthoquinodimethanes are discussed and approaches to their heterocyclic analogues are also reviewed. The utility of ortho-quinodimethanes in organic synthesis is highlighted by examples of both inter- and intramolecular Diels-Alder cycloadditions as the key steps in the total synthesis of naturally occurring polycyclic systems. In chapter two, work aimed at the development of a rapid synthetic entry to heterocyclic quinodimethanes starting from ortho-methyl heterocyclic carboxylic acids is presented. To this end, the dianion of 3-meth

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21

Mostert, Lelane. "Central oxygen pipeline failure." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/86313.

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Thesis (MMed)--Stellenbosch University, 2014.<br>ENGLISH ABSTRACT: Case Report - A case is described of central oxygen pipeline failure that occurred at a large academic hospital and its subsequent implications for managing the situation. Literature review - The literature review undertaken focused on the current state of affairs with regards to anaesthetic staff's knowledge of and preparedness for the management implications of central oxygen pipeline failure. The events I describe below demonstrate a significant deficiency in the staff’s understanding of and training for the crisis, whi

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22

Sieker, Anke. "Oxygen atom transfer reactions." Thesis, University of Edinburgh, 1994. http://hdl.handle.net/1842/12933.

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Oxygen atom transfer reactions in a series of early transition metal complexes in both solution and solid state were investigated, with a particular interest in O-atom transfer processes from bonded NO<SUB>x</SUB> (x= 1,2,3) ligands to adjacent carbonyl groups. The main objective was the synthesis and characterisation of new mixed CO/NO<SUB>2</SUB><SUP>-</SUP> species. In Chapter 1 a general review of oxygen atom transfer reactions involving CO and NO<SUB>x</SUB> is given. Chapter 2 presents the results gained from reactions of M<SUB>2</SUB>(CO)<SUB>10</SUB>, ClM(CO)<SUB>5</SUB> and several ot

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23

Li, Qian. "Electrochemical reduction of oxygen." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:2f37a1ae-dab0-4581-a8fd-e01ce59246c4.

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The main aim of the work reported is the design of proof-of-concept of at point-of-use hydrogen peroxide electrogeneration from air. The experimental work discussed within this thesis explores five major areas: the kinetics of electrocatalysis, ion-pairing, change of solvent media, the electrode surface modication by a redox mediator, and the electrochemical reduction of oxygen within enhanced mass transport systems. The electrocatalytic rates and mass transport of two oxygen reduction redox meditors, viz. anthraquinone and methyl viologen, are studied in aqueous solutions. The investigation i

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24

Olinde, Lindsay. "Sediment Oxygen Demand Kinetics." Thesis, Virginia Tech, 2007. http://hdl.handle.net/10919/42437.

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Hypolimnetic oxygen diffusers increase sediment oxygen demand (SOD) and, if not accounted for in design, can further exacerbate anoxic conditions. A study using extracted sediment cores, that included both field and laboratory experiments, was performed to investigate SOD kinetics in Carvinâ s Cove Reservoir, a eutrophic water supply reservoir for Roanoke, Virginia. A bubble-plume diffuser is used in Carvinâ s Cove to replenish oxygen consumed while the reservoir is thermally stratified. The applicability of zero-order, first-order, and Monod kinetics to describe transient and steady stat

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25

Amante, Joel C. "Oxygen diffusion in perovskites /." The Ohio State University, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487758178237154.

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26

Bondü, Christoph Johannes [Verfasser]. "Electrochemical Oxygen Reduction and Oxygen Evolution from DMSO Based Electrolytes / Christoph Johannes Bondü." Bonn : Universitäts- und Landesbibliothek Bonn, 2017. http://d-nb.info/114915442X/34.

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27

Injarabian, Louise. "Impact of oxygen and glucose differential availability on human neutrophil viability, metabolism and activation." Thesis, Bordeaux, 2020. http://www.theses.fr/2020BORD0272.

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Les neutrophiles sont les leucocytes les plus abondants dans la circulation sanguine et jouent un rôle clé dans l’immunité innée contre les agents pathogènes, en particulier les bactéries.Dans des conditions homéostatiques, les neutrophiles résident dans la moelle osseuse, où ils sont produits, et dans la fraction plasmatique du sang. Ces deux compartiments sont connus pour contenir de faibles quantités d'oxygène disponible (4 % et 1,2 % O2).En outre, les neutrophiles sont considérés comme des cellules hautement glycolytiques, ayant un faible nombre de mitochondries et produisant la majeure pa

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28

Broxterman, Ryan M. "The influence of oxygen delivery and oxygen utilization on the determinants of exercise tolerance." Diss., Kansas State University, 2015. http://hdl.handle.net/2097/19083.

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Doctor of Philosophy<br>Department of Anatomy and Physiology<br>Thomas J. Barstow<br>The physiological mechanisms determining the tolerable duration of exercise dictate human physical accomplishments across all spectrums of life. Despite extensive study, these specific mechanisms, and their dependence on oxygen delivery and oxygen utilization, remain, a certain extent, undefined. The purpose of this dissertation was to test the overarching hypothesis that muscle contraction characteristics (i.e., intensity of contraction, muscle contraction-relaxation duty cycle, etc.) alter oxygen delivery

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29

McGuire, Brooke Jamie. "Mathematical modeling of oxygen transport in skeletal muscle under conditions of high oxygen demand." Diss., The University of Arizona, 2003. http://hdl.handle.net/10150/280434.

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Maximal oxygen consumption rates in exercising skeletal muscle are studied using a Krogh-type cylinder model. Effects of the decline in oxygen content of blood flowing along capillaries, intravascular resistance to oxygen diffusion, and myoglobin-facilitated diffusion are included. Parameter values are based on human skeletal muscle. The model is used to predict oxygen consumption rates in exercising skeletal muscle, based on transport processes occurring at the microvascular level. The dependence of maximal oxygen consumption rates on oxygen demand, perfusion, and capillary density (defined a

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30

Tanay, Florent. "Étude des défauts liés à l'oxygène dans le silicium Czochralski destiné aux cellules solaires photovoltaïques – Influence des impuretés isovalentes." Thesis, Aix-Marseille, 2013. http://www.theses.fr/2013AIXM4353/document.

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Ce travail a pour but de comprendre les effets de deux principaux défauts liés à l’oxygène, les complexes bore-oxygène et les donneurs thermiques, sur les propriétés électriques et photovoltaïques du silicium. Plus particulièrement, les interactions des impuretés isovalentes, connues pour modifier la distribution spatiale de l’oxygène, avec ces défauts ont été étudiées. Deux protocoles expérimentaux ont d’abord été développés pour évaluer la dégradation de la durée de vie des porteurs de charge sous éclairement dans le silicium riche en fer. Ensuite, il a été mis en évidence que l’introduction

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31

Soares, Costa Josiane. "Magnetron sputtered ZnO layers : synthesis, characterization and oxygen reduction investigations." Thesis, Brest, 2019. http://www.theses.fr/2019BRES0037.

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La corrosion est un processus électrochimique impliquant une réaction d'oxydation (dissolution du métal) équilibrée par une réaction de réduction. La réduction de l’oxygène (ORR, oxygen reduction reaction) est l'une des principales réactions cathodiques en corrosion. L'oxygène peut être réduit directement en ions hydroxyle ou indirectement avec le peroxyde d'hydrogène comme espèce intermédiaire. Dans cette thèse de doctorat, l’ORR a été étudiée sur des couches de ZnO qui est un produit de corrosion commun du zinc, un métal de grand intérêt industriel. Des électrodes modèles (films de ZnO textu

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32

Kullgren, Jolla. "Oxygen Vacancy Chemistry in Ceria." Doctoral thesis, Uppsala universitet, Strukturkemi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-167521.

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Cerium(IV) oxide (CeO2), ceria, is an active metal oxide used in solid oxide fuel cells and for the purification of exhaust gases in vehicle emissions control. Behind these technically important applications of ceria lies one overriding feature, namely ceria's exceptional reduction-oxidation properties. These are enabled by the duality of the cerium ion which easily toggles between Ce4+ and Ce3+. Here the cerium 4f electrons and oxygen vacancies (missing oxygen ions in the structure) are key players. In this thesis, the nature of ceria's f electrons and oxygen vacancies are in focus, and exami

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33

Ebert, Benjamin L. "Oxygen regulation of gene expression." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.296895.

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34

Paliteiro, C. A. S. "Mechanistic studies on oxygen electroreduction." Thesis, University of Oxford, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.354852.

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35

Rowling, Simon. "Asymmetric epoxidations using molecular oxygen." Thesis, University of Hull, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.321047.

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36

Jeranko, Timo. "Photodissociation of the oxygen molecule." Thesis, University of Bristol, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492508.

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The aim of this work was to determine the distribution of photofragments of the O2 molecule in the Schumann-Runge continuum and bands, as well as their vector correlations and alignment parameters. Pontential energy curves were calculated ab initio using variational methods both in the equilibrium geometry and in the long range dissociation limit. To obtain the distribution of products, the molecule was dissociated in a molecular dynamics calculation, and the resulting vibrational wavepackets were analysed in the long range to obtain absorption cross-sections, yielding product distribution for

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37

Pheko, Tshepo. "Stereoselective synthesis of oxygen heterocycles." Thesis, University of Bristol, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.658071.

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The thesis describes the use of y,8-unsaturated alcohol in cyclisations with various aldehydes under acidic conditions to fonn monocyclic and bicyclic heterocycles with good stereocontrol. 6-Phenylhex-5-en-2-01136 was prepared in 3 steps and 55% yield and reacted with prop anal ill the presence of oxygen· and nitrogen nucleophiles to give tri-substituted tetrahydropyrans. Interestingly 229 and 230 have an equatorial C-3 side chain whereas 232 and 235 is in axial. Furthennore reaction of 6-phenylhex-5-en-2-01 136 with aldehydes possessing aryl, nitrogen and oxygen tethered nucleophiles suitably

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38

Eriksson, Adelina, and Viktoria Antoniou Karlsson. "Mobil flaskhållare för medicinsk oxygen." Thesis, KTH, Tillämpad maskinteknik (KTH Södertälje), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-147791.

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39

Duddy, Pamela E. "Electron scattering by molecular oxygen." Thesis, Queen's University Belfast, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.287611.

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40

Thomas, Malcolm. "Electron scattering by atomic oxygen." Thesis, Queen's University Belfast, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337031.

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41

Rawsthorne, Helen. "Oxygen regulation in Lactococcus lactis." Thesis, University of East Anglia, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323335.

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42

Fawkner, Samantha Gieva. "Oxygen uptake kinetics in children." Thesis, University of Exeter, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.393144.

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43

Smith, Cheryl. "Reactive oxygen species in atherosclerosis." Thesis, King's College London (University of London), 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.302549.

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44

Steadman, Janet Anne. "The mechanism of oxygen airglow." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241215.

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45

Wijesinghe, Meme. "Oxygen therapy in respiratory disorders." Thesis, Queen Mary, University of London, 2012. http://qmro.qmul.ac.uk/xmlui/handle/123456789/2511.

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Oxygen therapy remains a cornerstone of medical practice and is generally regarded as being safe. However, there is a lack of clinical evidence to support the routine use of oxygen therapy, and in certain conditions, injudicious oxygen may cause harm. In this thesis, I will present two audits and three randomised controlled trials of oxygen therapy. Methods  A prospective audit of the prescription and use of oxygen therapy before and after the introduction of an oxygen prescription section on a drug chart  A retrospective audit of ambulance oxygen administration, in patients with acute exace

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46

Buchwald, Carolyn. "Oxygen isotope systematics of nitrification." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/114328.

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Thesis: S.B., Massachusetts Institute of Technology, Department of Earth, Atmospheric, and Planetary Sciences, 2007.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 39-41).<br>During nitrification there is an exchange of oxygen atoms between water and nitrite, causing the [delta]¹⁸O of nitrate produced by nitrification to be closer to the [delta]¹⁸O of water than expected. A series of lab and field experiments were set up in order to quantify the exchange, and then calculate the [delta]¹⁸O of nitrate with these values. The lab experiments tested the excha

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47

McBride, Alan George. "Nitric oxide and oxygen metabolism." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624510.

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48

Tate, Edward William. "Anomeric oxygen to carbon rearrangements." Thesis, University of Cambridge, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624584.

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49

Thum, Tuck Foo. "Oxygen transfer in recirculating flow." Thesis, Virginia Tech, 1985. http://hdl.handle.net/10919/45829.

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<p>An experimental investigation was done on oxygen transfer into a laminar flow of whole blood and saline solutions downstream of an abrupt pipe expansion. This was used as the experimental model for regions of separated flow in the arterial system. The flow was fully-developed prior to the expansion with Reynolds numbers between 160 to 850. The results showed high transfer rates over most of the region downstream of the step, with maximum transfer occurring near the reattachment point. In addition, oscillations of the transfer rate were measured at the larger Reynolds numbers of 450

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50

Holliday, Katherine Frances. "Oxygen-enhanced MRI in cancer." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/oxygenenhanced-mri-in-cancer(bf84c0c5-0647-4035-8607-b1d62d940ea9).html.

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Tumour hypoxia is linked to reduced treatment sensitivity and poor outcome. Oxygen-enhanced MRI (OE-MRI) is a novel technique with the potential to non-invasively image hypoxia. It involves the measurement of MR relaxation rate changes caused by changes in oxygenation within blood and tissue. This thesis is focused on the development of OE-MRI and its clinical application in tumours. Two imaging sequences were optimised and then investigated for accuracy and precision in measuring oxygen enhanced R1 changes. Following that, R1, R2* and blood flow were measured during air and oxygen breathing i

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