Academic literature on the topic 'P.3539'

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Journal articles on the topic "P.3539"

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Ivanova, Elena P., Nataliya M. Gorshkova, Natalia V. Zhukova, et al. "Characterization of Pseudoalteromonas distincta-like sea-water isolates and description of Pseudoalteromonas aliena sp. nov." International Journal of Systematic and Evolutionary Microbiology 54, no. 5 (2004): 1431–37. http://dx.doi.org/10.1099/ijs.0.03053-0.

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Seven melanogenic Pseudoalteromonas distincta-like strains, KMM 3562T, KMM 3536, KMM 3537, KMM 3538, KMM 3539, KMM 3615 and KMM 3629, which expressed tyrosinases were isolated from sea-water samples collected from different locations in Amursky Bay (Sea of Japan, Pacific Ocean) and characterized to clarify their taxonomic position. By 16S rRNA gene sequence analysis, the bacteria were shown to belong to the genus Pseudoalteromonas. The G+C content of the DNAs of the strains was 41–43 mol%. The level of DNA similarity among these strains was conspecific (92–97 %), indicating that they represent
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Hixon, M. L., A. Gualberto, L. Demers, et al. "Correlation of plasma levels of free insulin-like growth factor 1 and clinical benefit of the IGF-IR inhibitor figitumumab (CP- 751, 871)." Journal of Clinical Oncology 27, no. 15_suppl (2009): 3539. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.3539.

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3539 Background: Free IGF-1 (fIGF-1) represents the biologically active fraction of IGF-1, the main circulating ligand of the Insulin-like Growth Factor type I Receptor (IGF-IR). Signaling through the IGF-IR induces tumor survival and resistance to cancer therapy. Figitumumab (F) (CP-751,871) inhibits IGF-1-induced IGF-IR autophosphorylation with an IC50 of 0.42 nmol/L. Methods: Plasma levels of fIGF-1 were measured in a phase 1b/2 multi-center study of Paclitaxel (T) and Carboplatin (C) and F in patients (pts) with treatment-naïve NSCLC. Other serum markers of the IGF-IR pathway, including ci
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Barutcu, Asya, Elizabeth Briasco, Jake Moon, et al. "Planned morning aerobic exercise in a fasted state increases energy intake in the preceding 24 h." European Journal of Nutrition 60, no. 6 (2021): 3387–96. http://dx.doi.org/10.1007/s00394-021-02501-7.

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Abstract Purpose We previously observed increased energy intake (EI) at the meal before planned afternoon exercise, but the proximity of the meal to exercise might have reduced the scale of the pre-exercise anticipatory eating. Therefore, this study examined EI in the 24 h before fasted morning exercise. Methods Fourteen males, experienced with gym-based aerobic exercise (age 25 ± 5 years, BMI 23.8 ± 2.5 kg/m2), completed counterbalanced exercise (EX) and resting (REST) trials. On day 1, subjects were told the following morning’s activity (EX/REST), before eating ad-libitum laboratory-based br
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Janson, Marcel E., Mathilde E. de Dood, and Marileen Dogterom. "Dynamic instability of microtubules is regulated by force." Journal of Cell Biology 161, no. 6 (2003): 1029–34. http://dx.doi.org/10.1083/jcb.200301147.

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Microtubules are long filamentous protein structures that randomly alternate between periods of elongation and shortening in a process termed dynamic instability. The average time a microtubule spends in an elongation phase, known as the catastrophe time, is regulated by the biochemical machinery of the cell throughout the cell cycle. In this light, observed changes in the catastrophe time near cellular boundaries (Brunner, D., and P. Nurse. 2000. Cell. 102:695–704; Komarova, Y.A., I.A. Vorobjev, and G.G. Borisy. 2002. J. Cell Sci. 115:3527–3539) may be attributed to regulatory effects of loca
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Koyama, Teruhide, Mizuho Maekawa, Etsuko Ozaki, Nagato Kuriyama, and Ritei Uehara. "Daily Consumption of Coffee and Eating Bread at Breakfast Time Is Associated with Lower Visceral Adipose Tissue and with Lower Prevalence of Both Visceral Obesity and Metabolic Syndrome in Japanese Populations: A Cross-Sectional Study." Nutrients 12, no. 10 (2020): 3090. http://dx.doi.org/10.3390/nu12103090.

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Background: The study aimed to investigate the association between daily consumption of coffee or green tea, with and without habitual bread consumption for breakfast, and components and prevalence of metabolic syndrome in Japanese populations. Methods: The study population consisted of 3539 participants (1239 males and 2300 females). Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using logistic regression analyses to evaluate the associations of daily coffee and green tea consumption with the prevalence of obesity, visceral obesity, and metabolic syndrome. Results: Coffe
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Margalit, Ofer, William S. Harmsen, Einat shacham-Shmueli, et al. "Evaluating gender as a predictive marker for response to bevacizuamb (Bev) in metastatic colorectal carcinoma (mCRC): Pooled analysis of 3369 patients (pts) in the ARCAD database." Journal of Clinical Oncology 37, no. 15_suppl (2019): 3539. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.3539.

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3539 Background: Previous studies suggest a possible gender-specific response to Bev in mCRC, showing a benefit in males, while the effect in females is less significant. Therefore, we evaluated response to Bev according to gender. Methods: Data from 3369 mCRC patients enrolled on 4 first-line randomized trials testing Bev (2000-2007) were pooled. Association between gender and progression-free survival (PFS)/overall survival (OS) was evaluated by stratified Cox regression model, adjusted for potential confounders. Predictive value was evaluated by interaction (inter.) effect between gender an
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Bendell, Johanna C., Tamara Sauri, Antonio Cubillo, et al. "Final results of the McCAVE trial: A double-blind, randomized phase 2 study of vanucizumab (VAN) plus FOLFOX vs. bevacizumab (BEV) plus FOLFOX in patients (pts) with previously untreated metastatic colorectal carcinoma (mCRC)." Journal of Clinical Oncology 35, no. 15_suppl (2017): 3539. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.3539.

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3539 Background: VEGF-A and ANG-2 have complementary roles in regulation of tumor angiogenesis. Targeting VEGF-A with BEV in combination chemotherapy (CT) in mCRC has proven to increase PFS and OS. ANG-2 is overexpressed and associated with poor outcome of mCRC pts receiving BEVcontaining treatment. Hence, dual blockade of VEGF-A and ANG-2 by the bispecific mAb VAN with standard CT may improve clinical activity in mCRC. Methods: All pts received mFOLFOX-6 and were randomized 1:1 to also receive intravenous VAN 2000 mg every other week (Q2W) (Arm A) or BEV 5 mg/kg Q2W (Arm B). The primary end p
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Schnadig, I. D., E. K. Fromme, C. L. Loprinzi, et al. "Prognostic significance of patient-physician disagreement about performance status in patients with advanced cancer." Journal of Clinical Oncology 25, no. 18_suppl (2007): 9021. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.9021.

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9021 Background: Physician-reported performance status (PS) is an important prognostic factor in advanced malignancies and is a commonly used stratification variable in cancer clinical trials. However, the extent, predictors, and prognostic importance of disagreement in PS assessment between physicians and patients have not been examined. Methods: Using NCCTG clinical trials from 1987–1990 (J Clin Oncol 19(15):3539–3546, 2001), we analyzed the difference and agreement of PS (ECOG and Karnofsky [KPS]) and nutritional status assessments reported by physicians and patients individually. The degre
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Ellenbogen, A., Y. Gidoni, N. Rotfarb, and M. Michaeli. "P-353." Fertility and Sterility 86, no. 3 (2006): S266. http://dx.doi.org/10.1016/j.fertnstert.2006.07.709.

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Luo, W. Y., and L. Liu. "Abstract P-353." Pediatric Critical Care Medicine 19 (June 2018): 155. http://dx.doi.org/10.1097/01.pcc.0000537810.92560.c4.

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Dissertations / Theses on the topic "P.3539"

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Wang, Estelle Weiping. "Les partitions pour pipa de Dunhuang : édition et interprétation." Thesis, Paris 4, 2016. http://www.theses.fr/2016PA040169.

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Les partitions pour pipa de Dunhuang (fin dynastie Tang, début époque Song), copiées sur les manuscrits P. 3539, P. 3808 et P. 3719 conservés à la BnF ont été découvertes par Paul Pelliot en 1908 dans la grotte numéro 17 du site de Mogao en Chine. Cette thèse décrit les influences musicales et culturelles apportées en Chine par la route la soie, notamment la musique koutchéenne, puis réalise le bilan des études de ces partitions, menées depuis plus de soixante-quinze ans par les plus grands spécialistes dont Hayashi Kenzō, Ren Erbei, Rao Zongyi, Ye Dong, He Changlin, Chen Yingshi, Xi Zhenguan,
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Tiethof-Aronson, Adrian K. "The wheel of great compassion| A study of Dunhuang manuscript p.3538." Thesis, Temple University, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=1597130.

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<p> Of the thousands of Buddhist manuscripts discovered at Dunhuang, there are many examples of non-official <i>s&umacr;tras</i> and <i> dh&amacr;ran&dotbelow;&imacr;</i> collections more difficult to identify than those with titles identical to canonical <i>s&umacr;tras</i>. Manuscript collection catalogs are the first sources consulted when one undertakes research involving manuscripts and in order to be a truely valuable resource, they need to reflect current scholarship. This thesis studies the Dunhuang manuscript, Pelliot <i>chinois</i> 3538, from different perspectives, examining its rit
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Arriada, Eduardo. "A educa??o secund?ria na prov?ncia de S?o Pedro do Rio Grande do sul : a desoficializa??o do ensino p?blico." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2007. http://tede2.pucrs.br/tede2/handle/tede/3539.

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Made available in DSpace on 2015-04-14T14:22:36Z (GMT). No. of bitstreams: 1 399709.pdf: 7611919 bytes, checksum: 0230e844ab4d3dfe9f7142a3fa004dc0 (MD5) Previous issue date: 2007-12-14<br>Este trabalho tem como objetivo demonstrar como no s?culo XIX o modelo de educa??o adotado no Brasil, ocasionou na Prov?ncia de S?o Pedro do Rio Grande do Sul a desoficializa??o do ensino secund?rio. Dentro desse modelo, os Liceus, institui??es oficiais, como os col?gios, institui??es particulares, travaram uma disputa constante no intuito de formar as elites. Enquanto institui??es escolares, os regulamento
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Book chapters on the topic "P.3539"

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Taber, Douglass F. "Development of Flow Reactions." In Organic Synthesis. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780190200794.003.0015.

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For a review of a monograph by C. Wiles and P. Watts on applications of flow reactors in organic synthesis, see Org. Process. Res. Dev. 2011, 15, 947. For a review by Klavs S. Jensen of MIT of flow approaches, see Angew. Chem. Int. Ed. 2011, 50, 7502. Hans-René Bjørsvik of the University of Bergen described (Org. Process. Res. Dev. 2011, 15, 997) a multijet oscillating disc microreactor, and Andreas Schmid of the Technische Universität Dortmund (Adv. Synth. Catal. 2011, 353, 2511) and László Poppe of the Budapest University of Technology and Economics discussed (Adv. Synth. Catal. 2011, 353, 2481) continuous flow reactors for biotransformations. Gases are readily handled in a flow apparatus. S. Chandrasekhar of the Indian Institute of Chemical Technology, Hyderabad demonstrated (Tetrahedron Lett. 2011, 52, 3865) partial deuteration of 1 to 2, using D2O as the deuterium source. Peter H. Seeberger of the Max Planck Institute, Potsdam oxidized (Org. Lett. 2011, 13, 5008) 3 to 4 with singlet oxygen. Dong-Pyo Kim of Chungnam National University and Robert H. Grubbs of Caltech effected (Org. Lett. 2011, 13, 2398) ethenolysis of 5 to give 6 and 7. Takashi Takahashi of the Tokyo Institute of Technology showed (Chem. Commun. 2011, 47, 12661) that even phosgene could be handled in a flow system, using it to activate 8 for condensation with benzylamine to give 9. In the liquid phase, Stephen L. Buchwald of MIT prepared (Angew. Chem. Int. Ed. 2011, 50, 8900) 11 by the fluorination of 10. Jesús Alcázar of Janssen Pharmaceutical, Toledo, showed (Tetrahedron Lett. 2011, 52, 6058) that a nitrile 12 could be reduced in a flow system to the aldehyde 13. Mark York of CSIRO prepared (Tetrahedron Lett. 2011, 52, 6267) the furan 16 by condensation of 14 with 15. Floris P.J.T. Rutjes of Radboud University Nijmegen used (Org. Process Res. Dev. 2011, 15, 783) the careful controls of a flow reactor to optimize the exothermic combination of 17 with 18 to give 19. Professor Buchwald demonstrated (Angew. Chem. Int. Ed. 2011, 50, 10665) a flow protocol for the lithiation of 20 with in situ borylation and Pd-catalyzed coupling with 21 to give 22.
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Conference papers on the topic "P.3539"

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Leon, Carlos G., Ankur Midha, Stephen D. Lee, Sheila J. Thornton, and Kishor M. Wasan. "Abstract 3532: P-glycoprotein downregulation using RNAi decreases cholesterol efflux from human renal cancer cells." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-3532.

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Myreng, Y., K. Gjesdal, S. E. Kjeldsen, K. Lande, I. Eide, and H. Grendahl. "PLATELET RELEASE DURING EXERCISE IN PACEMAKER PATIENTS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643496.

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Seven pacemaker patients with complete AV-block were studied during one to three week periods of either ventricular (VVI), or atrio-ventricular pacing (DDD) or triggered ventricular pacing (VAT)At rest, the plasma p-thromboglobulin (BTG), arterial adrenaline and nor-adrenaline as well as atrial rate were not significantly different during standard and physiological pacing. Following ergometer bicycling, BTG increased significantly (p &lt;0.004), and more so in VVI pacing (from 38 ±15 to 73 ±15 ng/ml) compared to DDD (27 ±6 to 44 ±13),p&lt;0.05. Arterial plasma adrenaline at baseline was 60 ±27
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Winckler, Pascale, Rodolphe Jaffiol, Hamid Morjani, Regis Deturche, Pascal Royer, and Pierre Jeannesson. "Abstract 3537: P-glycoprotein expression level is responsible for alterations in plasma membrane microfluidity as probed by fluorescence correlation spectroscopy." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-3537.

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"Konsentrasi VFA dan pH Cairan Rumen Kambing Kejobong yang Diberi Pakan dengan Imbangan Hijauan dan Konsentrat Berbeda." In Teknologi Peternakan dan Veteriner Mendukung Kemandirian Pangan di Era Industri 4.0. Pusat Penelitian dan Pengembangan Peternakan, 2019. http://dx.doi.org/10.14334/pros.semnas.tpv-2019-p.353-358.

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Holmes, W. E., H. R. Lijnen та D. Collen. "CHARACTERIZATION OFα2-ANTIPLASMIN.REACTIVE SITE VARIANTS PRODUCED BY SITE-DIRECTED MUTAGENESIS". У XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644766.

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α2-Antiplasmin (α2AP) is the primary physiological plasmin inhibitor in human plasma. The inhibition is rapid (second order rate constants (k1) are expressed as M−1 s−1 ) (k1 = 2 × 107) and occurs as the consequence of an irreversible 1:1 stoichiometric complex formation; the exact nature of and the forces involved in complex formation are not fully understood. In fact, what makes α2AP an inhibitor, rather than simply a substrate remains unresolved. Recently, we deduced the primary structure of α2 AP from the sequence of its cDNA. 95%of this sequence was confirmed by amino acid (aa) sequence a
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