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Journal articles on the topic 'P-Chlorobenzaldehyde'

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Published: 2 June 2025

Last updated: 31 July 2025

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1

Atta-Allah, Saad R., Wael S. I. Abou-Elmagd, Kamal A. A. Kandeel, Magdy M. Hemdan, David S. A. Haneen, and Ahmed S. A. Youssef. "Synthesis and Antimicrobial Activity Evaluation of Some Novel Hydrazone, Pyrazolone, Chromenone, 2-Pyridone and 2-Pyrone Derivatives." Journal of Chemical Research 41, no. 11 (2017): 617–23. http://dx.doi.org/10.3184/174751917x15065183733150.

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A cyanoacetohydrazide derivative underwent a series of reactions with different nucleophilic reagents, such as hydrazine hydrate, p-chlorobenzaldehyde and salicylaldehyde, to give the condensation products. In addition, an arylidene malononitrile was reacted with different nitrogen nucleophiles, such as hydrazine hydrate, thiocarbohydrazide and cyanoacetohydrazide, to afford the hydrazine, hydrazone and pyridin-2-one derivatives, respectively. Furthermore, a pyridin-2-one derivative was reacted with different carbon electrophiles, such as carbon disulfide, p-chlorobenzaldehyde and acetic anhyd

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2

Zhou, Wei-Fang, Lang Chen, Jun Xie, Chak-Tong Au, and Shuang-Feng Yin. "Efficient synthesis of p-chlorobenzaldehyde through liquid-phase oxidation of p-chlorotoluene using manganese-containing ZSM-5 as catalyst." RSC Advances 5, no. 91 (2015): 74162–69. http://dx.doi.org/10.1039/c5ra16206h.

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3

D., K. SHARMA, MADHU, and K. SHARMA V. "Electrochemical Reduction of p-Chlorobenzaldehyde at Copper and Amalgamated Copper Electrodes." Journal of Indian Chemical Society Vol. 72, Feb 1995 (1995): 127–28. https://doi.org/10.5281/zenodo.5901136.

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<em>Department of Chemistry. University of Rajasthan. Jaipur-302 004 Manuscript received 2 July 1992, revised 6 September 1993, accepted 3 November 1993</em> Electrochemical Reduction of <em>p</em>-Chlorobenzaldehyde at Copper and Amalgamated Copper Electrodes

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4

Akishina, Е. А., V. А. Knizhnikov, L. А. Popova, and Е. G. Karankevich. "Synthesis of N-aryl and pyridine-substituted derivatives of valine, leucine and isoleucine." Proceedings of the National Academy of Sciences of Belarus, Chemical Series 60, no. 2 (2024): 145–52. http://dx.doi.org/10.29235/1561-8331-2024-60-2-145-152.

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A preparative method for the synthesis of N-aryl- and pyridine-substituted valine, leucine, isoleucine derivatives by condensation of amino acids sodium salts with benzaldehyde, salicylaldehyde, vanillin, p-chlorobenzaldehyde, 3-pyridinecarbaldehyde and subsequent reduction with sodium borohydride has been developed.

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5

Kumar, Ashwini, Baldev Singh, Ashok Kumar Malik, and Dhananjay K. Tiwary. "Determination of Some Aldehydes by Using Solid-Phase Microextraction and High-Performance Liquid Chromatography with UV Detection." Journal of AOAC INTERNATIONAL 90, no. 6 (2007): 1689–94. http://dx.doi.org/10.1093/jaoac/90.6.1689.

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Abstract A new approach has been developed for the extraction and determination of aldehydes such as veratraldehyde, m-nitrobenzaldehyde, cinnamaldehyde, benzaldehyde, and p-chlorobenzaldehyde by using solid-phase microextraction (SPME) and high-performance liquid chromatography with UV detection (HPLC/UV). The method involves adsorption of the aldehydes on polydimethylsiloxane/divinylbenzenecoated fiber, followed by desorption in the desorption chamber of the SPME-HPLC interface, using acetonitrilewater (70 + 30) as the mobile phase; UV detection was at 254 nm. A good separation of 5 aldehyde

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6

Anoopjit, Singh Kooner, Sharma S., and Sharma Poonam. "Synthesis and microbial activity of acrylamides with heteroatoms." Journal of Indian Chemical Society Vol. 91, Feb 2014 (2014): 293–98. https://doi.org/10.5281/zenodo.5749142.

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Department of Chemistry, Punjab Agricultural University, Ludhiana-141 004, Punjab, India <em>E-mail </em>: ajsingh@live.in Department of Plant Breeding and Genetics, Punjab Agricultural University, Ludhiana-141 004, Punjab, India E-mail : sonita_311@rediffmail.com; poonam_sharma@pau.edu <em>Manuscript received 05 September 2012, revised 11 March 2013, accepted 18 April 2013</em> The modified condensation reaction of benzaldehyde (1a), 2-chlorobenzaldehyde (1c), 3-nitrobenzaldehyde (1b) and 4-chlorobenzaldehyde (1d) with <strong>α</strong>-proton containing acids viz. acetic acid (2a) and

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7

Xie, Jun, Lang Chen, Wei-Fang Zhou, Chak-Tong Au, and Shuang-Feng Yin. "Selective oxidation of p-chlorotoluene to p-chlorobenzaldehyde over metal-modified OMS-2 molecular sieves." Journal of Molecular Catalysis A: Chemical 425 (December 2016): 110–15. http://dx.doi.org/10.1016/j.molcata.2016.09.038.

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8

Journal, Baghdad Science. "Synthesis and Characterization of New Metal Complexes of α-Aminonitriles Derived from P- Toluidine and Aromatic Aldehydes." Baghdad Science Journal 7, no. 3 (2010): 1214–25. http://dx.doi.org/10.21123/bsj.7.3.1214-1225.

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New metal complexes of some transition metal ions Co(II), Cu(II) , Cd(II) and Zn(II) were prepared by their reaction with previously prepared ligands HLI= (P-methyl anilino) phenyl acetonitrile and HLII = (P-methyl anilino) –P– chloro phenyl acetonitrile . The two ligands were prepared by Strecker’s procedure which includ the reaction of p- toluidine with benzaldehyde and P- chlorobenzaldehyde respectively. Structures were proposed depending on atomic absorption , i.r. and u.v.visible spectra in addition to magnetic susceptibility and electrical conductivity measurements.

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9

Majeed, Rawa'a A., та Kh Abd-AL-Hassan. "Synthesis and Characterization of New Metal Complexes of α-Aminonitriles Derived from P- Toluidine and Aromatic Aldehydes". Baghdad Science Journal 7, № 3 (2010): 1214–25. http://dx.doi.org/10.21123/bsj.2010.7.3.1214-1225.

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New metal complexes of some transition metal ions Co(II), Cu(II) , Cd(II) and Zn(II) were prepared by their reaction with previously prepared ligands HLI= (P-methyl anilino) phenyl acetonitrile and HLII = (P-methyl anilino) –P– chloro phenyl acetonitrile . The two ligands were prepared by Strecker’s procedure which includ the reaction of p- toluidine with benzaldehyde and P- chlorobenzaldehyde respectively. Structures were proposed depending on atomic absorption , i.r. and u.v.visible spectra in addition to magnetic susceptibility and electrical conductivity measurements.

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10

Deng, Yi-Qiang, Teng Zhang, Chak-Tong Au, and Shuang-Feng Yin. "Liquid-phase catalytic oxidation of p-chlorotoluene to p-chlorobenzaldehyde over manganese oxide octahedral molecular sieves." Applied Catalysis A: General 467 (October 2013): 117–23. http://dx.doi.org/10.1016/j.apcata.2013.07.015.

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11

Deng, Yi-Qiang, Teng Zhang, Chak-Tong Au, and Shuang-Feng Yin. "Oxidation of p-chlorotoluene to p-chlorobenzaldehyde over manganese-based octahedral molecular sieves of different morphologies." Catalysis Communications 43 (January 2014): 126–30. http://dx.doi.org/10.1016/j.catcom.2013.09.026.

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12

Sawhney, S. S., and Gopal Chettri. "pH-Metric studies on tris(p-chlorobenzaldehyde-thiosemicarbazonato)M(III) (M = Pr, Nd)." Thermochimica Acta 120 (October 1987): 357–58. http://dx.doi.org/10.1016/0040-6031(87)80231-9.

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13

KHAN, ASHIQ, POONAM SHARMA, RAJNIKANT, VIVEK K. GUPTA, NARESH PADHA, and REKHA SHARMA. "Synthesis and crystal structure of [chlorobis(triphenylphospino)(p-chlorobenzaldehyde thiosemicarbazone)] copper(I) complex." Journal of Chemical Sciences 128, no. 2 (2016): 185–91. http://dx.doi.org/10.1007/s12039-015-1030-8.

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14

Liu, Jia-Xue, Shi-Yu Zhang, Meng-Xiao Tai, Wei Li, and Zhonglu You. "Synthesis, Characterization and X-Ray Crystal Structures of Aroylhydrazones Derived from 2-Chlorobenzaldehyde with Various Benzohydrazides." Acta Chimica Slovenica 71, no. 4 (2024): 587–94. https://doi.org/10.17344/acsi.2024.8967.

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Reaction of 2-chlorobenzaldehyde with 3-trifluoromethylbenzohydrazide, 3,5-dimethoxybenzohydrazide, 4-trifluoromethylbenzohydrazide and 2-bromobenzohydrazide, respectively, in methanol afforded four new aroylhydrazones. The newly synthesized compounds were characterized by means of elemental analysis, IR and 1H NMR spectroscopy, and their structures were further confirmed by X-ray single crystal determination. The compounds were assayed for their antibacterial activities against E. coli, P. aeruginosa, B. subtilis, and S. aureus and show interesting results.

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15

Zhang, Teng, Yi-Qiang Deng, Wei-Fang Zhou, Chak-Tong Au, and Shuang-Feng Yin. "Selective oxidation of p-chlorotoluene to p-chlorobenzaldehyde with molecular oxygen over zirconium-doped manganese oxide materials." Chemical Engineering Journal 240 (March 2014): 509–15. http://dx.doi.org/10.1016/j.cej.2013.10.094.

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16

Mahmoud, N. M. Yousif, ElRashedy Ahmed, and M. Yousif Nabil. "New and Facile Synthesis of 2-Chloro-1,3-diketones." INTERNATIONAL JOURNAL OF CHEMISTRY AND CHEMICAL PROCESSES 8, no. 1 (2022): 28–33. http://dx.doi.org/10.56201/ijccp.v8.no1.2022.pg28.33.

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Background: Development of new methods for preparation of organic compounds is one of our major interests. Aims: we aim to develop a new synthetic procedure to prepare previously reported compounds and novel compounds. Methods: The methods that we used in this manuscript are novel. Results: 1,1-Dichoro-actone reacts with different aliphatic and aromatic aldehydes namely acetaldehyde, decanal, benzaldehyde, p-chlorobenzaldehyde, p-flourobenzaldehyde, naphthaldehyde, 5-methylfuran-2-carbaldehyde, thiophene-2-carbaldehyde, and nicotinaldehyde. The reaction is in alkaline media using potassium hyd

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17

Wang, Jiaqiang, Hua Fang, Ying Li, Junjie Li, and Zhiying Yan. "Liquid phase oxidation of p-chlorotoluene to p-chlorobenzaldehyde over cobalt-doped mesoporous titania with a crystalline framework." Journal of Molecular Catalysis A: Chemical 250, no. 1-2 (2006): 75–79. http://dx.doi.org/10.1016/j.molcata.2006.01.040.

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18

Anwar, Chairil, Yogo Dwi Prasetyo, Sabirin Matsjeh, Winarto Haryadi, Eti Nurwening Sholikhah, and Nendrowati Nendrowati. "Synthesis of Chalcone Derivatives and Their in vitro Anticancer Test Against Breast (T47D) and Colon (WiDr) Cancer Cell Line." Indonesian Journal of Chemistry 18, no. 1 (2018): 102. http://dx.doi.org/10.22146/ijc.26864.

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The synthesis of chalcone derivatives as target compounds and anticancer test against breast (T47D) and colon (WiDr) cell line had been performed. The synthesis was performed by Claisen-Schmidt condensation by using acetophenone and benzaldehyde derivatives. The anticancer activity test of chalcone derivatives was carried out by MTT assay against T47D and WiDr cell lines. The synthesis was started by reacting 4-hydroxyacetophenone and benzaldehyde derivatives such as p-anisaldehyde (chalcone A [(E)-4'-hydroxy-4-methoxychalcone]), veratraldehyde (chalcone B [(E)-4'-hydroxy-3,4-dimethoxychalcone

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19

LIZENG, WANG, MA CHENGSONG, ZHANG XIAOLI, SHEN DAZHONG, and GUO SHOUPENG. "Adsorption Voltammetry Determination of Lysine Traces of its o-Chlorobenzaldehyde Derivative." Journal of Indian Chemical Society Vol. 75, Aug 1998 (1998): 488–90. https://doi.org/10.5281/zenodo.5936337.

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Chemistry College, Shandong University, Jinan, 250100 P. R. China Shandong Metallurgical Institute, Jinan, 250100, P. R. China <em>Manuscript received 10 September 1997, revised 22 December 1997, accepted 10 March 1998</em> An adsorption voltammetric method for the determination of lysine is reported, based on the reduction of the Schiff base compound formed by lysine and <em>o</em>-chlorobenzaldehyde in phosphate buffer solution (pH 11.1). The Schiff base product can be adsorbed on a hanging mercury drop electrode and reduced with peak potential of about -1.15 V (vs SCE). The derivative peak

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20

Elečko, Pavol, Štefan Toma, Miroslav Vrúbel, and Eva Solčániová. "Reactivity of [m]ferrocenophanones: The aldol condensation." Collection of Czechoslovak Chemical Communications 51, no. 5 (1986): 1112–18. http://dx.doi.org/10.1135/cccc19861112.

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Investigation of the reaction of [m]ferrocenophanones with p-chlorobenzaldehyde in basic medium showed that these cyclic ketones are much more reactive than their acyclic counterparts. The size of the bridge and the position of the carbonyl group influenced the reaction. Thus, [m]ferrocenophan-1-ones (m =3,4 afforded β-hydroxyketones only, [5]ferrocenophan-1-one gave in addition an α,β-unsaturated ketone, and [4]ferrocenophane-2-one yielded only α,β-unsaturated ketones. Oxidation of [m]ferrocenophanes with MnO2 furnished the expected monoketones and [4]ferrocenophane-1,4-dione and [5[ferroceno

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21

Cai, Yan-Hua. "Synthesis and Structure Optimization of Schiff Base Derived from p-Chlorobenzaldehyde and p-Aminobenzoic Acid by Rapid Efficient Gas Impacting Reaction." Asian Journal of Chemistry 26, no. 18 (2014): 6199–201. http://dx.doi.org/10.14233/ajchem.2014.17137.

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22

Rodríguez Enciso, Duván A., Carlos E. Puerto Galvis, and Vladimir V. Kouznetsov. "2-(4-Chlorophenyl)-4-(3,4-dimethoxy-phenyl)-6-methoxy-3-methylquinoline." Molbank 2022, no. 2 (2022): M1383. http://dx.doi.org/10.3390/m1383.

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A 2,4-diarylquinoline derivative, 2-(4-chlorophenyl)-4-(3,4-dimethoxyphenyl)-6-methoxy-3-methylquinoline, was synthesized in a conventional two-step procedure from p-anisidine, p-chlorobenzaldehyde and methyl isoeugenol as available starting reagents through a sequence of BF3·OEt2-catalyzed Povarov cycloaddition reaction/oxidative dehydrogenation aromatization processes under microwave irradiation conditions in the presence of a green oxidative I2-DMSO system. The structure of the compound was fully characterized by FT-IR, 1H and 13C-NMR, ESI-MS, and elemental analysis. Its physicochemical par

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23

Ooi, Takashi, Yuichiro Arimura, Yukihiro Hiraiwa, et al. "Highly enantioselective monoalkylation of p-chlorobenzaldehyde imine of glycine tert-butyl ester under mild phase-transfer conditions." Tetrahedron: Asymmetry 17, no. 4 (2006): 603–6. http://dx.doi.org/10.1016/j.tetasy.2006.01.019.

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24

Zakaria, H. Aiube* Ali H. Samir Israa SH. A. R. Al Kadi. "DESIGN, SYNTHESIS, CHARACTERIZATION OF SOME NEW SUBSTITUTED CHALCONES AND STUDIES THEIR ANTIMICROBIAL ACTIVITIES." INTERNATIONAL JOURNAL OF ENGINEERING SCIENCES & RESEARCH TECHNOLOGY 5, no. 6 (2016): 750–60. https://doi.org/10.5281/zenodo.55982.

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Eight designed chalcones, named [1(p-benzenesulphonamidophenyl)-3-p-chloro-2-propene-1-one][2], [1(p-benzenesulphonamidophenyl)-3-p-nitro-2-propene-1-one][3], [1(4-Ureido)phenyl-3-p-chlorophenyl-2-propene-1-one][5], [1(4-Ureido)phenyl-3-p-nitroophenyl-2-propene-1-one][6], [1(4(p-N-methylaminophenyl)azophenyl-3-p-chlorophenyl-2-propene-1-one][8], [1(4(p-N-methylaminophenyl)azophenyl-3-p-nitroophenyl-2-propene-1-one][9], [1(p-aminophenyl)-3-p-chlorophenyl-2-propene-1-one][10] and [1(p-aminophenyl)-3-p-nitrophenyl-2-propene-1-one][11], were synthesised by condensation of synthesised p-acetylpheny

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25

Kumar, Nitin, and Sanjay Sharma. "SYNTHESIS AND ANTICANCER ACTIVITY OF N-SUBSTITUTED INDOLE DERIVATIVES." INDIAN DRUGS 58, no. 12 (2022): 16–21. http://dx.doi.org/10.53879/id.58.12.12496.

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Thizolidine-2,4-dione (1), on reaction with p-fluorobenzaldehyde in the presence of piperidine and toluene, gives (Z)-5-(2-fluororobenzylidin)-thiazolidin-2,4-dione (2), which on reaction with indole and o-chlorobenzaldehyde in the presence of ethanol yielded final derivatives i.e (Z)-5-(4-fluororobenzylidene)-3-[(1H-indol-1-yl) (substituted phenyl) methyl] thiazolidine-2,4-dione (3a-3e). All the synthesized compounds were characterized by UV, FTIR, 1 H NMR, MASS spectroscopy and elemental analysis. These compounds were screened for their anticancer activity against MCF-7 human breast cancer c

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26

A., A. Hassanien, Zahran M.A., A. EI-Gaby M.S., and M. Ghorab M. "Utility of 2-amino-4,5,6,8-tetrahydro-7 H-chromene-3-carbonitriles in synthesis of chromeno[2,3-d]pyrimidine and chromeno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives of pharmaceutical interest." Journal of Indian Chemical Society Vol. 76, Jul 1999 (1999): 350–54. https://doi.org/10.5281/zenodo.5848718.

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Department of Chemistry, Faculty of Education Suez canal University, Al-Arish. Egypt Department of Chemistry, Faculty of Science, Al-Azhar University, Cairo, Egypt Department of Chemistry, Faculty of Science, Al-Azhar University at Assiut, Assiut 71524, Egypt Department of Drug Radiation Research, National Center for Radiation Research and Technology, Cairo, Egypt <em>Manuscript received 29 October 1997, revised 8 September 1998, accepted 9 March 1999</em> Chromeno[2,3-d]pyrimidines (5, 6 and 8) have been prepared by the reaction of 2-amino-7,7-dimethy1-4-substitutedphenyl5-oxo-4,5,6,8-te

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27

Hossain, M. I., and M. M. H. Bhuiyan. "Synthesis and Antimicrobial Activities of Some New Thieno and Furopyrimidine Derivatives." Journal of Scientific Research 1, no. 2 (2009): 317–25. http://dx.doi.org/10.3329/jsr.v1i2.2299.

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Fused pyrimidines, 8,9-dimethyl[1,2,4]triazolo[4,3-c]thieno[3,2-e]pyrimidine 5, 3,8,9-trimethyl[1,2,4]triazolo[4,3-c]thieno[3,2-e]pyrimidine 6, 4-benzylidinehydrazono-5,6 dimethylthieno[2,3-d]pyrimidine 7, 4-[4/-hydroxybenzylidine]hydrazono-5,6-dimethylthi-eno[2,3-d]pyrimidine 8, 4-[4/-tolylidin]hydrazono-5,6-dimethylthieno[2,3-d]pyrimidine 9, 4-[4/-nitrobenzylidine]hydrazono-5-ethyl-6-methylthieno[2,3-d]pyrimidine 10 and 4-[4/-chlorobenzylidine]hydrazono-5-ethyl-6-methylthieno[2,3-d]pyrimidine 11 are prepared in good yield by an initial treatment of 2-amino-4,5-dimethylthiophene-3-carbonitril

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28

Abd El-Wahab, Ashraf Hassan Fekry, and Hany Mostafa Mohamed. "Synthesis and DFT Study of 7-Bromophenylnaphthopyran Moieties." Asian Journal of Chemistry 35, no. 8 (2023): 1819–26. http://dx.doi.org/10.14233/ajchem.2023.28032.

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A one-pot, three-component reaction of 6-bromo-2-naphthol (1), p-chlorobenzaldehyde (2) and malononitrile or ethyl cyanoacetate (3) in ethanol/piperidine under reflux was performed to afford 4H-naphtho[2,1-b]pyrano-3-carbonitrile (4a) and ethyl 4H-naphtho[2,1-b]pyrano-3-carboxylate (4b) derivatives, respectively. The structure of these compounds was determined using IR, 1H NMR, 13C NMR, mass spectroscopy and UV-Vis spectra. The molecular geometry of compounds 4a and 4b was determined at the B3LYP/631+G(d) level. The geometric optimization was performed on two tautomers and two conformers. Taut

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29

Subotin, Vladyslav V., Vitalii M. Asaula, Yulian L. Lishchenko, et al. "Catalytic Reductive Amination of Aromatic Aldehydes on Co-Containing Composites." Chemistry 5, no. 1 (2023): 281–93. http://dx.doi.org/10.3390/chemistry5010022.

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The performance of a series of cobalt-based composites in catalytic amination of aromatic aldehydes by amines in the presence of hydrogen as well as hydrogenation of quinoline was studied. The composites were prepared by pyrolysis of CoII acetate, organic precursor (imidazole, 1,10-phenantroline, 1,2-diaminobenzene or melamine) deposited on aerosil (SiO2). These composites contained nanoparticles of metallic Co together with N-doped carboneous particles. Quantitative yields of the target amine in a reaction of p-methoxybenzaldehyde with n-butylamine were obtained at p(H2) = 150 bar, T = 150 °C

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30

Ghosh, Aniruddha, Rumpa Saha, Kakali Mukherjee, et al. "Rate enhancement via micelle encapsulation for room temperature metal catalyzed Ce(IV) oxidation of p-chlorobenzaldehyde to p-chlorobenzoic acid in aqueous medium at atmospheric pressure." Journal of Molecular Liquids 190 (February 2014): 81–93. http://dx.doi.org/10.1016/j.molliq.2013.10.029.

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31

Shyam, Abhijit, Amit K. Pradhan та Paritosh Mondal. "A Density Functional Theory Study on Et-BAC-Catalyzed 1,6-Conjugate Addition of p-Chlorobenzaldehyde to p-Quinone Methide for the Synthesis of α,α′-Diarylated Ketones". Journal of Organic Chemistry 86, № 13 (2021): 9040–54. http://dx.doi.org/10.1021/acs.joc.1c01014.

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32

Ahmed N Alhakimi, Ahmed N. Alhakimi, Thikra A. Almuhanna Jawza Sh Alnawmasi Thikra A Almuhanna Jawza Sh Alnawmasi, and S. El Sayed Saeed and Ebtesam H. L. Alhamzi S El Sayed Saeed and Ebtesam H L Alhamzi. "Synthesis, Spectroscopic Characterization, and Anticancer Activity of Metal Complexes with a Novel Schiff Base Ligand from -Diketone Derivatives." Journal of the chemical society of pakistan 44, no. 6 (2022): 596. http://dx.doi.org/10.52568/001184/jcsp/44.06.2022.

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A new series complexes of Ni(II), Mn(II), Co(III), Cu(II), Cr(II), Zn(II), Zr(IV), Cd(II), and La(III) prepared by the reaction of the metal salt with a new Schiff base ligand. This Schiff base obtained by the condensation of p-phenylenediamine, 4-chlorobenzaldehyde, and acetyl acetone. The confirmation of the ligand and its metal complexes were characterized by multiple techniques such as, elemental analyses, magnetic susceptibility studies, FTIR 1H, 13C-NMR, XRD, molar conductance, UV-vis spectral analyses, and thermal analyses. The conductivity measurements of the complexes in DMF solutions

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C., P. PRABHAKARAN, and L. HARI KUMARAN NAIR M. "Oxomolybdenum(v) and Dioxomolybdenum(VI) Complexes of Schiff Bases derived from Isonicotinic Acid Hydrazide." Journal of Indian Chemical Society Vol. 75, Jan 1998 (1998): 7–10. https://doi.org/10.5281/zenodo.5913001.

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Department of Chemistry, University of Kerala, Kariavattom, Trivandrum-695 581 Department of Chemistry, Government College of Engineering, Trivandrum <em>Manuscript received 1 March 1996, revised 14 November 1996, accepted 10 January 1997</em> Several new oxoMo<sup>V </sup>and dioxoMo<sup>VI</sup> complexes of Schiff bases derived from isonicotinic acid hydrazide (INH) and salicylaldehyde (INHSAL), furan-2-aldehyde (INFAL), 2-hydroxy-1-naphthaldehyde (INHNAL), 4-dimethylaminobenzaldehyde (INHDAB), 2- hydroxyacetophenone (INHHAP) or <em>p</em>-chlorobenzaldehyde (INHPCB) have been prepared, hav

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34

Chen, Yuan, Yingqi Mi, Xueqi Sun, et al. "Novel Inulin Derivatives Modified with Schiff Bases: Synthesis, Characterization, and Antifungal Activity." Polymers 11, no. 6 (2019): 998. http://dx.doi.org/10.3390/polym11060998.

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In this paper, we report chemical modifications of inulin by seven kinds of aromatic Schiff bases, which are different from their substituent groups. The obtained inulin derivatives were confirmed by FTIR, 1H NMR, and 13C NMR. Then, we studied their antifungal activity against four kinds of plant pathogens involving Botrytis cinerea, Fusarium oxysporum f. sp. cucumerium Owen, Fusarium oxysporum f. sp. niveum, and Phomopsis asparagi by the mycelium growth rate method. The results revealed that all inulin derivatives were endowed with significant antifungal activity compared to inulin. Among the

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Nursofia, Baiq Ike, Yehezkiel Steven Kurniawan, Jumina Jumina, et al. "One-Pot Synthesis and <i>In Vitro</i> Studies of Calix[4]-2-methylresorcinarene Derivatives as Antimalarial Agents Against <i>Plasmodium falciparum</i> Chloroquine-Resistant Strain FCR-3." Indonesian Journal of Chemistry 24, no. 6 (2024): 1717. https://doi.org/10.22146/ijc.94885.

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Malaria is an endemic disease in Indonesia caused by infection from the Plasmodium parasite. Recently, antimalarial resistance significantly contributed to the decline in the cure rate of malaria sufferers. In this work, three calix[4]resorcinarenes have been synthesized from 2-methylresorcinol and different benzaldehyde derivatives, i.e., 4-chlorobenzaldehyde, 4-methoxybenzaldehyde, and 4-dimethylaminobenzaldehyde through the one-pot synthesis procedure. The calix[4]resorcinarenes synthesis was done through a cyclo-condensation reaction by using HCl 37% as the catalyst and ethanol as the solv

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Ali K Neama Allamy and Sarah Ajwad Mejbel. "Preparation, characterization and biological activity of some new seven-membered heterocyclic compounds." World Journal of Advanced Research and Reviews 15, no. 1 (2022): 662–78. http://dx.doi.org/10.30574/wjarr.2022.15.1.0744.

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Introduction: The synthesis of Schiff base has huge importance to prepare a lot of heterocyclic compounds, Oxazepines can be prepared by reaction of imine compounds with anhydrides to obtain seven-membered heterocyclic compound. Materials and Methods: A series of 1, 3-oxazepine derivatives were prepared, firstly preparation of the imines (S1-S2) from reaction of 2-chlorobenzaldehyde with each of p-toluidine and 4, 4’-Methylenedianiline and using glacial acetic acid as a catalyst. The second step involves the reaction of prepared Schiff bases (S1-S2) with both 3-nitrophthalic anhydride and Itac

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Ji, Zhi Xiang, and Peng Fei Li. "Crystal Structure and Catalytic Activity of A Novel Cd(II) Coordination Polymer Formed by Dicarboxylic Ligand." Bulletin of Chemical Reaction Engineering & Catalysis 13, no. 2 (2018): 220. http://dx.doi.org/10.9767/bcrec.13.2.1178.220-226.

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A new Cd(II) coordination polymer, {[Cd3(L)2(DMF)2(H2O)2]·H2O}n (H2L = 1,3-bisbenzyl-2-imidazolidine-4,5-dicarboxylic acid) was synthesized by one-pot synthesis method from 1,3-bisbenzyl-2-imidazolidine-4,5-dicarboxylic acid, NaOH, DMF, and Cd(NO3)2·4H2O. Its structure was determined by elemental analysis and single crystal X-ray diffraction. Structural analysis shows that three Cd(II) ions are all six-coordinated with four oxygen atoms of four 1,3-bisbenzyl-2-imidazolidine-4,5-dicarboxylate ligands and two O atoms from two DMF molecules (Cd1) or two oxygen atoms of two coordinated H2O molecul

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V., N. Patange, and R. Arbad B. "Transition metal complexes of dehydroacetic acid chalcone : Synthesis, spectral, thermal and fungicidal study." Journal of Indian Chemical Society Vol. 84, Nov 2007 (2007): 1096–103. https://doi.org/10.5281/zenodo.5824503.

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Department of Chemistry, Shri Chhatrapati Shivaji College, Omerga, Dist. Osmanabad-413 606, Maharastra, India Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad-431 004, Maharashtra, India <em>E-mail</em> : abr_chem@yahoo.co.in <em>Manuscript received 15 February 2007, revised 7 August 2007, accepted 7 August 2007</em> Transition metal complexes containing bidentate O, O donor ligand, i.e. 3-[3-(4-chloro-phenyl)-4-hydroxy-6- methyl-pyran-2-one derived from 3-acetyl-6-methyl-pyran-2,4(3<em>H</em>)-dione (dehydroacetic acid) and <em>p</em>-chlorobenzaldehyde,

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Ali, K. Neama Allamy, and Ajwad Mejbel Sarah. "Preparation, characterization and biological activity of some new seven-membered heterocyclic compounds." World Journal of Advanced Research and Reviews 15, no. 1 (2022): 662–78. https://doi.org/10.5281/zenodo.7746147.

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<strong>Introduction: </strong>The synthesis of Schiff base has huge importance to prepare a lot of heterocyclic compounds, Oxazepines can be prepared by reaction of imine compounds with anhydrides to obtain seven-membered heterocyclic compound. <strong>Materials and Methods</strong>: A series of 1, 3-oxazepine derivatives were prepared, firstly preparation of the imines (S1-S2) from reaction of 2-chlorobenzaldehyde with each of p-toluidine and 4, 4’-Methylenedianiline and using glacial acetic acid as a catalyst. The second step involves the reaction of prepared Schiff bases (S1-S2)

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40

Abbas, Zahra Mohammed, and Rasmia Mahmood Rumez. "SYNTHESIS, CHARACTERIZATION AND SCREENING OF ANTIMICROBIAL ACTIVITY FOR SOME NEW SCHIFF BASES AND THIAZOLIDINONE DERIVATIVES DERIVED FROM AROMATIC CARBOXYLIC ACID." ChemChemTech 68, no. 7 (2025): 27–34. https://doi.org/10.6060/ivkkt.20256807.7189.

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In this study, the antimicrobial properties of newly synthesized Schiff bases (4a-4e) and thiazolidinone compounds (5a-5e) generated from 3,5-dinitrobenzoic acid were assessed. These compounds were obtained by reacting 3,5-dinitrobenzoic acid (1) with ethanol in a few drops of concentrated H2SO4 to produce the ester (2). The acid hydrazide (3), which was produced by treating the ester with hydrazine hydrate, reacted with the proper aldehydes, including 4-bromobenzaldehyde, 4-chlorobenzaldehyde, 4-hydroxybenzaldehyde, 4-methoxybenzaldehyde, and 4-hydroxy-3-methoxybenzaldehyde, respectively, to

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Abd Elhady, Hebe, Hossa AL-SHAREEF, Khadeega Takroni, and Wedad Alharbi. "One-Pot Synthesis of New Bipyridine and Yerpyridine Derivatives: Anti-proliferative Evaluation, DNA Flow Cytometry Analysis, and Molecular Docking Study." Acta Poloniae Pharmaceutica - Drug Research 81, no. 3 (2024): 423–37. http://dx.doi.org/10.32383/appdr/191341.

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Some new bipyridine derivatives were synthesized using 2-oxo-4-(pyridin-3-yl)-6-(thiophen-2-yl)-1,2-dihydropyridine-3-carbonitrile 1a. While terpyridine derivatives were synthesized using 2-oxo-4-(pyridin-3-yl)-6-(pyridin-4-yl)-1,2-dihydropyridine-3-carbonitrile 1b as starting material. Alkylation of compounds 1a, b gave the alkyl derivatives 2a, b which converted into aceto hydrazides 3a,b. Treating the aceto hydrazides with ethyl cyanoacetate afforded 2'-(2-(3,5-dioxopyrazolidin-1-yl)-2-oxoethoxy)-6'-(thiophen-2-yl)-3,4'-bipyridine-3'-carbonitrile 4a and 6'-[2-(3,5-dioxopyrazolidin-1-yl)-2-o

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42

Cahyono, Robby Noor, Selfira Arum Andari, and Tutik Dwi Wahyuningsih. "Synthesis of <i>N</i>-Phenylpyrazoline Derivative from 4-Chlorobenzaldehyde and 4-Chloroacetophenone and its Activity as an Antimalarial Agent." Materials Science Forum 1061 (May 26, 2022): 211–16. http://dx.doi.org/10.4028/p-wah85x.

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This study was aimed to synthesize N-phenylpyrazoline derivative and evaluate its antimalarial activity. The pyrazoline was synthesized from chalcone derivative through a cyclo- condensation reaction. Moreover, chalcone derivative was prepared from 4-chlorobenzaldehyde and 4-chloroacetophenone through Claisen-Schmidt condensation. The structure elucidation of the products was performed by FTIR, GC-MS, 1H- and 13C-NMR spectrometers. The antimalarial assay was conducted by inhibition of heme polymerization. The chalcone was obtained as a white solid in 83% yield, while N-phenylpyrazoline derivat

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Sari, Diah Kartika, Danny Danny Nur Wahyu Hidayat, Dwi Rahmasari Fatmawati, Sugeng Triono, Yehezkiel Steven Kurniawan, and Jumina Jumina. "Synthesis and Antimalarial Activity Assay of <i>C</i>- Arylcalix[4]pyrogallolarenes Using Heme Polymerization Inhibition Activity (HPIA) Method." Materials Science Forum 1061 (May 26, 2022): 187–93. http://dx.doi.org/10.4028/p-5w4b49.

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Malaria is one of the most devastating and widespread tropical parasitic diseases in developing countries with high prevalence. Furthermore, antimalarial drug resistance results in a global resurgence of malaria. Thus there is an urgent need to find new and active antimalarial agents. In this work, we reported the synthesis of C-arylcalix[4]pyrogallolarenes and their in vitro activity assay as new antimalarial agent candidates. The C-arylcalix[4]pyrogallolarenes were prepared in high yields through a condensation reaction between pyrogallol and aromatic aldehydes (i.e., benzaldehyde, 4-hydroxy

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Mustika, Chessy Rima, Endang Astuti, and Muhammad Idham Darussalam Marjan. "Molecular Docking, Synthesis and <i>In Vitro</i> Antiplasmodium Assay of Monoketone Curcumin Analogous from 2-Chlorobenzaldehyde." Indonesian Journal of Chemistry 24, no. 3 (2024): 638. http://dx.doi.org/10.22146/ijc.81122.

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This research aimed to develop new curcumin analogous as antiplasmodium candidates. Six curcumin analogous (1-6) were proposed and docked against three Plasmodium falciparum receptors, namely PfENR, PfLDH, and PfATP6. The docking studies were carried out to predict the interaction among the compounds and receptors as well as their binding affinity. Three curcumin analogous (3, 4, and 6), which displayed specific interactions with the target receptors and possessed the lowest binding affinity were further proceeded to synthesis and in vitro antiplasmodium assay. Synthesis of the analogous 3, 4,

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REDDY, P. R., and S. B. RAO. "ChemInform Abstract: Polarographic and Cyclic Voltammetric Reduction of p-Chlorobenzaldehyde Isonicotinoylhydrazone." ChemInform 19, no. 35 (1988). http://dx.doi.org/10.1002/chin.198835071.

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Gudivada, Sridevi* Mrs. KattepoguNaga Kumari SK.shakeela Mrs.Chowpati Ramya Pedamallu Niharika Mrs. Syed Meraj Sultana Mrs. Jasmine Shaik. "SYNTHESIS AND ANTI-MICROBIAL ACTIVITY OF 4-ACETYL MORPHOLINE CHALCONES." October 6, 2023. https://doi.org/10.5281/zenodo.8414574.

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<em>The current study examined that the Chalcones are abundant in edible plants and are considered as the precursors of flavonoids and iso-flavonoids. Claisen–Schmidt condensation is a method used for preparing Chalcones, which is an important class of flavonoids. They have a wide range of biological operations and industrial applications. Due to the excessive importance of β-unsaturated carbonyl moiety and due to a broad range of natural and synthetically designed products, the development of novel synthetic methods remains interested in the research area to synthesize chalcones an

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Trivedi, Mahendra Kumar, Alice Branton, Dahryn Trivedi, Gopal Nayak, Khemraj Bairwa, and Snehasis Jana. "Physicochemical and Spectroscopic Characterization of p-Chlorobenzaldehyde: An Impact of Biofield Energy Treatment." Insights in Analytical Electrochemistry 1, no. 1 (2015). https://doi.org/10.5281/zenodo.35194.

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p-Chlorobenzaldehyde (p-CBA) is used as an important chemical intermediate for the preparation of pharmaceuticals, agricultural chemicals, dyestuffs, optical brighteners, and metal finishing products. The study aimed to evaluate the effect of biofield energy treatment on the physicochemical and spectroscopic properties of p-CBA. The study was accomplished in two groups i.e. control and treated. The control group was remained as untreated, while the treated group was subjected to Mr. Trivedi’s biofield energy treatment. Finally, both the samples (control and treated) were evaluated using

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Trivedi, Mahendra Kumar, Alice Branton, Dahryn Trivedi, Gopal Nayak, Khemraj Bairwa, and Snehasis Jana. "Physicochemical and Spectroscopic Characterization of p-Chlorobenzaldehyde: An Impact of Biofield Energy Treatment." Insights in Analytical Electrochemistry 1, no. 1 (2015). https://doi.org/10.5281/zenodo.168371.

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p-Chlorobenzaldehyde (p-CBA) is used as an important chemical intermediate for the preparation of pharmaceuticals, agricultural chemicals, dyestuffs, optical brighteners, and metal finishing products. The study aimed to evaluate the effect of biofield energy treatment on the physicochemical and spectroscopic properties of p-CBA. The study was accomplished in two groups i.e. control and treated. The control group was remained as untreated, while the treated group was subjected to Mr. Trivedi’s biofield energy treatment. Finally, both the samples (control and treated) were evaluated using

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Kumar Trivedi, Mahendra, and Alice Branton. "Physicochemical and Spectroscopic Characterization of p-Chlorobenzaldehyde: An Impact of Biofield Energy Treatment." Insights in Analytical Electrochemistry 1, no. 1 (2015). http://dx.doi.org/10.21767/2470-9867.100005.

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Trivedi, Mahendra, Gopal Nayak, Dahryn Trivedi, and Alice Branton. "Physicochemical and Spectroscopic Characterization of p-Chlorobenzaldehyde: An Impact of Biofield Energy Treatment." Imedpub, October 29, 2015. https://doi.org/10.5281/zenodo.813571.

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p-Chlorobenzaldehyde (p-CBA) is used as an important chemical intermediate for the preparation of pharmaceuticals, agricultural chemicals, dyestuffs, optical brighteners, and metal finishing products. The study aimed to evaluate the effect of biofield energy treatment on the physicochemical and spectroscopic properties of p-CBA. The study was accomplished in two groups i.e. control and treated. The control group was remained as untreated, while the treated group was subjected to Mr. Trivedi's biofield energy treatment. Finally, both the samples (control and treated) were evaluated using variou

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