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1

Delp, M. D., R. O. Manning, J. V. Bruckner, and R. B. Armstrong. "Distribution of cardiac output during diurnal changes of activity in rats." American Journal of Physiology-Heart and Circulatory Physiology 261, no. 5 (November 1, 1991): H1487—H1493. http://dx.doi.org/10.1152/ajpheart.1991.261.5.h1487.

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Rat locomotor and feeding behavior varies on a diurnal basis; at night the animals actively forage and eat, whereas during the day they are more inactive and somnolent. At night, cardiac output is higher, presumably for enhanced perfusion of the active muscles to support increased metabolism and for enhanced perfusion of the digestive organs to support increased digestion and nutrient absorption. Conversely, it is hypothesized that during the daytime, blood flow to these two tissues is relatively low. The purpose of this study was to test these hypotheses by measuring cardiac output and the distribution of cardiac output in rats at various times in the diurnal cycle (8:00 A.M., 4:00 P.M., and 8:00 P.M.). The radiolabeled microsphere technique was used to measure cardiac output and distribution of blood flow to the tissues. Distribution of the total cardiac output was accounted for by complete dissection, weighing, and counting of organs and carcass. Cardiac output at 8:00 P.M. (136 +/- 9 ml/min) was elevated 13% (P less than 0.05) over that at 4:00 P.M. The proportion of the cardiac output distributed to the skeletal muscles (4:00 P.M.: 25%; 8:00 P.M.: 27%) and to the digestive tract (4:00 P.M.: 14%; 8:00 P.M.: 14%) did not change between the two time periods. Thus total muscle blood flow increased (P less than 0.05) from 31 +/- 2 at 4:00 P.M. to 36 +/- 4 ml/min at 8:00 P.M.; the only digestive organ to show a significant increase in blood flow from 4:00 P.M. to 8:00 P.M. was the stomach (133 +/- 17 to 166 +/- 19 ml/min, respectively).(ABSTRACT TRUNCATED AT 250 WORDS)
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ANDRUSHCHENKO, N. "FACTORS THE FORMATION OF NATIONAL SELF-CONSCIOUSNESS AND EDUCATION IN BELARUS (second half of XIX – beginning of XX century)." Herald of Polotsk State University. Series E. Pedagogical sciences, no. 1 (June 3, 2024): 2–5. http://dx.doi.org/10.52928/2070-1640-2024-41-1-2-5.

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The article defines the concept of «national self-consciousness». The works of famous teachers, ethnographers, folklorists Y.F. Krachkovski, N.Y. Nikiforovski, I.I. Nosovich, E.R. Romanov, P.V. Shein, P.I. Shpilevsky, I.A. Serbov, A.K. Serzhputovski, who researched and collected the oral folk art of Belarusians (proverbs, sayings, rites, songs, traditions) are presented. Examples of ritual songs are given, which were reflected in P.M. Shpilevsky's book «Belarus in Rites and Fairy Tales». The factors of formation of national consciousness and enlightenment in Belarus in the second half of the XIX - early XX centuries are characterized. Attention is emphasized on the activities of Orthodox brotherhoods, actively engaged in educational activities. The article considers the peculiarities of the organization and implementation of local lore and Belarusization in the framework of education of the younger generation in the period under consideration.
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3

Hatchi, Vanessa, Aymeric Guillot, and Nicolas Robin. "Revisiting Motor Imagery Guidelines in a Tropical Climate: The Time-of-Day Effect." International Journal of Environmental Research and Public Health 20, no. 10 (May 18, 2023): 5855. http://dx.doi.org/10.3390/ijerph20105855.

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(1) Background: Motor imagery (MI) is relevantly used to improve motor performance and promote rehabilitation. As MI ability and vividness can be affected by circadian modulation, it has been proposed that MI should ideally be performed between 2 p.m. and 8 p.m. Whether such a recommendation remains effective in a hot and humid environment, such as a tropical climate, remains unknown. (2) Methods: A total of 35 acclimatized participants completed a MI questionnaire and a mental chronometry test at 7 a.m., 11 a.m., 2 p.m., and 6 p.m. Visual (VI) and kinesthetic imagery (KI) abilities, as well as temporal congruence between actual walking and MI, were collected. Ambient temperature, chronotypes, thermal comfort, affect, and fatigue were also measured. (3) Results: VI scores were higher at 6 p.m. than at 7 a.m., 11 a.m., and 2 p.m., and temporal congruence was higher at 6 p.m. than at 7 a.m. Comfort, thermal sensation, and positive affect scores were higher at 7 a.m. and 6 p.m. (4) Conclusion: Data support greater imagery ability and accuracy when participants perceive the environment as more pleasant and comfortable. MI guidelines typically provided in neutral climates should therefore be adapted to tropical climates, with MI training sessions ideally scheduled in the late afternoon.
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Masbahi, Karima, Nadia Manar, Omar Laraqui, Frédéric Deschamps, and Chakib El Houssine Laraqui Hossini. "P-396 ANALYSIS OF THE REPERCUSSIONS OF SHIFT WORK AMONG ELECTROMECHANICS COMPLAINING OF DYSSOMNIA AND PROPOSAL FOR A NEW SHIFT SCHEDULE." Occupational Medicine 74, Supplement_1 (July 1, 2024): 0. http://dx.doi.org/10.1093/occmed/kqae023.1064.

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Abstract Introduction The objective was to analyze the repercussions of shift work (the rotation was 6 mornings from 6 a.m. to 2 p.m. with 01 day of rest then 6 afternoons from 2 p.m. to 10 p.m. with 1 day of rest and 6 nights from 10 p.m. until 6 a.m. with 6 days of rest) among electromechanics complaining of dyssomnia and to propose a new shift schedule Method This study, carried out among 30 electromechanics, included a clinical examination, a questionnaire including sociodemographic and professional data, an Epworth scale, a sleep diary and a grid of arduousness of staggered hours. The Epworth scale measures daytime sleepiness, it is based on a self-assessment of the probability of falling asleep. It is considered abnormal if > 10. The sleep diary is a self-assessment which allows the subject to note the quality of sleep and waking up which are assessed on a discontinuous scale: very good, good, average, bad, very bad. Results Epworth scale scores were greater than 10 in all participants. The sleep diaries showed the quality of sleep and that of waking up were considered average, bad or very bad by all people. The average score of the arduousness grid was 60.5%. Discussion and conclusion A proposal for a new rapid rotation schedule (2 mornings from 6 a.m. until 2 p.m. then 2 p.m. from 2 p.m. until 10 p.m. and 2 nights from 10 p.m. until 6 a.m. with 4 days rest) was suggested while respecting the same number of teams and the same number of employees.
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5

Korneyev, Igor A., Ruslan D. Zasseev, Ol’ga B. Pashina, Ali E. Mamedov, Pavel S. Kondrashkin, and Oleg A. Krylov. "Analysis of diurnal variability of sperm donors’ semen parameters." Urologicheskie vedomosti 9, no. 1 (May 24, 2019): 11–16. http://dx.doi.org/10.17816/uroved9111-16.

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Introduction. Diurnal variability of sperm parameters is controversial and should be considered during medical evaluation and solicitation of sperm donors. Aim: to evaluate diurnal variability of sperm parameters of anonymous sperm donors in reproductive medicine center. Materials and methods. Records of 1253 semen samples analysis of 39 sperm donors (mean age 27.1 ± 3.9 years) were retrospectively studied in reproductive medicine center in Saint Petersburg. Semen analysis was performed according to WHO 2010 recommendations. Diurnal variations of semen volume, sperm concentration, total sperm number, progressive motility and number of progressively motile sperm were analyzed. Results. Mean ejaculate volume, sperm total number and number of progressively motile sperm were higher after 3 p.m. (t = 5.63, p < 0.0001; t = 3.66, p = 0.0003 and t = 1.76, p = 0.078, respectively), while sperm concentration and percent of progressively motile sperm was lower (t = 2.03, p = 0.043 and t = 4.63, p = 0.0003, respectively).The lowest and the highest mean sperm numbers were registered in time slots between 12 a.m.–1 p.m. and 4 p.m.–5 p.m., respectively. Conclusions. The study suggests the diurnal variability of sperm donors’ semen parameters. We might recommend a potential sperm donor preservation to be performed after 3 p.m., preferentially within 4 p.m.–5 p.m. interval.
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6

Cortney Davis. "Doctor, 8 P.M." Literature and Medicine 11, no. 1 (1992): 86. http://dx.doi.org/10.1353/lm.2011.0265.

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7

Garner, R., Y. Zhao, and M. Gillingham. "After 3 p.m." Computers in Human Behavior 16, no. 3 (May 2000): 223–26. http://dx.doi.org/10.1016/s0747-5632(00)00002-9.

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8

Jury, Deborah L. "7:05 P.M." Journal of Pediatric Nursing 22, no. 6 (December 2007): 510–12. http://dx.doi.org/10.1016/j.pedn.2007.10.002.

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9

Malae, Peter Nathaniel. "The O'Reilly Factor at 5 P.M., 8 P.M., 1 A.M." Missouri Review 27, no. 2 (2004): 54–77. http://dx.doi.org/10.1353/mis.2004.0058.

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10

Paul, Rajendra D., and Martin G. Helander. "Effect of Sit-Stand Schedule on Spinal Shrinkage fn VDT Operators." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 39, no. 10 (October 1995): 563–67. http://dx.doi.org/10.1177/154193129503901005.

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A controlled field study was conducted to measure spinal shrinkage in office employees with sit-stand type workstations. Thirteen office employees, ten healthy and three with spinal disorders participated in the study. Using a stadiometer, changes in stature were measured at 8 a.m., 12 p.m., 1 p.m. and 5 p.m. From 12 p.m. to 1 p.m., all subjects sat for 40 minutes and walked for 20 minutes. Out of the ten healthy employees, six were instructed to stand for 30 minutes four times during the day. The remaining four subjects stood eight times 15 minutes each. Office workers who stood in 30 minute sessions experienced significantly less shrinkage than those who stood in 15 minute sessions. Office workers with spinal disorders also stood eight times 15 minutes each. They incurred a greater variability in the shrinkage pattern.
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11

จิยพงศ์, ปฏิญญา, and จันทร์ฉาย ยศศักดิ์ศรี. "การพัฒนาคุณภาพน้ำมันปาล์มสําหรับการทอดอาหารโดยใช้สารสกัดจากสมุนไพร." วารสารวิทยาศาสตร์ประยุกต์ กรมวิทยาศาสตร์บริการ 7, no. 7 (October 7, 2022): 95–103. http://dx.doi.org/10.60136/bas.v7.2018.222.

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วัตถุประสงค์ของการศึกษานี้คือการทดลองผลิตน้ำมันปาล์มผสมสารต้านออกซิเดชันเพื่อลดการเกิดกลิ่นหืนโดยใช้สมุนไพร 3 ชนิด คือ ขิง ขมิ้น และกระชาย การศึกษาปริมาณสารฟีนอลิกรวมของสมุนไพรทั้ง ขิง ขมิ้น และกระชาย เมื่อความเข้มข้นของ สมุนไพรมากขึ้นส่งผลให้ปริมาณสารประกอบฟีนอลิกเพิ่มขึ้น และเมื่อทดลองผลิตน้ำมันปาล์มผสมสมุนไพรผงโดยใช้สมุนไพร ผง 2% 4% และ 6% และน้ำมันปาล์มผสมสารสกัดจากสมุนไพรที่สกัดด้วยเอทานอล โดยใช้ความเข้มข้นของสารสกัดที่3 ระดับ คือ 200 400 และ 600 mg/kg วิเคราะห์คุณภาพที่สําคัญของน้ำมันผสมสารสกัด ได้แก่ ค่า Peroxide value (P.V.) และ ค่า Acid value (A.V) ซึ่งสูตรที่คัดเลือกคือ น้ำมันปาล์มผสมขิงผง 2% ขมิ้นผง 4% และกระชายผง 2% มีค่า P.V. คือ 5.500.22 6.200.04 และ6.180.08 meg/kg ส่วนน้ำมันปาล์มผสมสารสกัดจากสมุนไพรด้วยวิธีการสกัดด้วยเอทานอล ได้สูตรที่คัดเลือก คือ น้ำมันปาล์มผสมสารสกัดจากขิง 200 ขมิ้น 400 และกระชาย 400 mg/kg มีค่า P.M. คือ 4.480.03 5.600.02 และ5.820.01 meg/kg ผลการวิเคราะห์คุณภาพน้ำมันที่ผ่านการทอด พบว่าน้ำมันปาล์มผสมสารสกัดจากขิงที่ระดับ 200 mg/kg มีค่า P.v.คือ 6.560.06 ซึ่งมีค่าต่ํากว่าน้ำมันทุกสูตรอย่างมีนัยสําคัญทางสถิติ สําหรับการทดสอบการยอมรับทางประสาทสัมผัสโดยใช้ผู้ ทดสอบ จํานวน 30 คน ให้การยอมรับในด้านกลิ่นห็นคือ ข้าวเกรียบที่ทอดในน้ำมันปาล์มผสมสารสกัดจากขิง ข้าวเกรียบที่ทอด ในน้ำมันปาล์มผสมสารสกัดจากกระชาย ข้าวเกรียบที่ทอดในน้ำมันปาล์มผสมสารสกัดจากขมิ้นและข้าวเกรียบที่ทอดในน้ำมัน ปาล์มที่ไม่ผสมสารสกัด ตามลําดับการศึกษาอายุการเก็บน้ำมันผสมสารสกัดสูตรทดลองมีอายุการเก็บอย่างน้อย 1 ปี
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12

Takho-Godi, Elena. "Yuly Aykhenvald and Petr Bitsilli: Reconstruction of the philosophical and aesthetic dialogue." Literary Fact, no. 16 (2020): 322–36. http://dx.doi.org/10.22455/2541-8297-2020-16-322-336.

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The article compares for the first time the philosophical and aesthetic views on Russian literature and language of two prominent representatives of Russian abroad — the critic Yu.I. Aykhenvald (1872–1928) and the medievalist, interpreter of Russian classics P.M. Bitsilli (1879–1953). A full overview of factual materials identified to date is given, confirming the mutual interest of Yu.I. Aykhenvald and P.M. Bitsilli: documents from P.M. Bitsilli collection at the Institute of Russian literature (Pushkin House) of the RAS, Yu.I.Aykhenvald’s review from the Berlin newspaper “Rul'”on P.M. Bitsilli’s “Studies on Russian Poetry”, obituary of Yu.I. Aykhenvald, which was published by P.M. Bitsilli in the Sofia newspaper “Golos”. Among the issues raised are the impact which Aykhenvald’s immanent method of analyzing a literary text had on P.M. Bitsilli’s aesthetically individualizing method, the approaches of both authors to solving the morphology of Russian culture and philosophy of the nation, the connection of the Pushkin theme with thoughts about the fate of post-revolutionary Russia and Russian language in their works, which they articulated during the discussion of S. and A. Volkonsky’s book “In defense of the Russian language”.
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13

Oliveira, L. R. De, A. R. B. Marques, D. Da Silva, W. B. Sidião, W. S. Dos Santos, V. A. Amorim, L. P. Borges, and F. S. Matos. "Growth of Eucalyptus urocam Under Different Irrigation Managements." Journal of Agricultural Science 11, no. 4 (March 15, 2019): 92. http://dx.doi.org/10.5539/jas.v11n4p92.

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The objective of the present study was to evaluate the effects of different water irrigation managements on the growth of Eucalyptus urocam plants. The experiment was conducted in a greenhouse at the Goi&aacute;s State University, Ipameri campus, Brazil, using 100-day-old Eucalyptus urocam seedlings, which were transplanted into pots with 5 kg of substrate. A completely randomized experimental design with five replications was used, in a 2 &times; 4 factorial arrangement consisting of two daily irrigation depths (50%, and 100% of the substrate retention capacity) and four irrigation times (7:30 a.m., 11:30 a.m., 4:30 p.m., and 7:00 p.m.). The treatments were applied when the plants were 120 days old, and last 18 days, then, the variables were analyzed. E. urocam plants subjected to water deficit had high stomatal sensitivity, reduced transpiration rate, and maintained hydration, which are characteristics of isohydric plants. E. urocam plants irrigated at 4:30 p.m. or 7:00 p.m. presented low stomatal sensitivity and high biomass accumulation potential. Therefore, irrigations between 4:30 p.m. and 7:00 p.m. are recommended for Eucalyptus urocam plants at the initial growth stage.
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Rodríguez, Gerardo, Luis A. Moreno, Antonio Sarría, Jesús Fleta, and Manuel Bueno. "Assessment of Nutritional Status and Body Composition in Children Using Physical Anthropometry and Bioelectrical Impedance: Influence of Diurnal Variations." Journal of Pediatric Gastroenterology and Nutrition 30, no. 3 (March 2000): 305–9. http://dx.doi.org/10.1002/j.1536-4801.2000.tb02731.x.

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ABSTRACTBackground:To observe whether there are diurnal variations when assessing children's body composition, using physical anthropometric and bioelectrical impedance (BI) methods.Methods:In 32 children (18 females and 14 males) aged between 7.1 and 14.9 years, weight, height, arm circumference (AC), four skinfolds, and total body impedance (Z) were measured at 8 A.M., 12 noon, 4 P.M., and 8 P.M. on the same day. Body mass index (BMI), skinfolds sum (SS), total body water (TBW), fat‐free mass (FFM), and fat mass (FM) were also calculated at these times.Results:Height at 8 P.M. was 1.156 ± 0.54 cm less than at 8 A.M. (P < 0.001) and BMI increased 0.434 ± 0.29 kg/m2 at 8 P.M. (P < 0.001). Weight, SS and AC underwent no significant changes in the course of the day. Z was 5.83% less at 8 P.M. than at 8 A.M. (P < 0.001), yielding a TBW and FFM increase at 8 P.M. of 0.855 ± 1.061 and 1.173 ± 1.47 kg, respectively (P < 0.001).Conclusions:In children there is a diurnal decrease in height, impedance and FM, and an increase in BMI, TBW, and FFM. These factors must be taken into account when using such methods for assessing nutritional status in childhood.
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Han, Yong-Seop, Hyung-Bin Lim, Soo-Hyun Lee, and Jung-Yeul Kim. "Diurnal Variation in Choroidal and Retinal Thickness of the Early Treatment of Diabetic Retinopathy Study Macular Subfields Determined Using Swept-Source Optical Coherence Tomography." Ophthalmologica 233, no. 3-4 (2015): 192–97. http://dx.doi.org/10.1159/000375538.

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Purpose: To describe diurnal variation in choroidal thickness (CT) and retinal thickness (RT) of the nine Early Treatment of Diabetic Retinopathy Study (ETDRS) macular subfields determined using swept-source optical coherence tomography. Methods: A prospective study was conducted on 24 healthy Korean volunteers who underwent two sequential measurements of a randomly selected eye at 9 a.m., 1 p.m., and 6 p.m. The radial scan mode was used. To determine the repeatability and reliability, we applied intragrader agreement using the intraclass correlation coefficient (ICC). Results: Significant diurnal variation in CT was observed. The highest mean CT was found at 9 a.m. The lowest mean CT occurred at 1 p.m. There was excellent intragrader agreement, with the ICC ranging from 0.961 to 0.997. There was no significant diurnal variation in RT. Conclusion: There was significant diurnal variation in CT. The choroid was thinner at 1 p.m. than at 9 a.m. and 6 p.m.
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Mendonca, Filipe A., Rodrigo Taveira, Victor Dos Anjos, Izabelle Da Silva, Felipe Ponte, and Bruno Mesquita. "PSXIV-6 Late-Breaking: Evaluation of the heat tolerance in Girolando cows." Journal of Animal Science 97, Supplement_3 (December 2019): 332–33. http://dx.doi.org/10.1093/jas/skz258.665.

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Abstract The breeds that present better adaptations to the climate of the region where they are raised may present greater productive advantages in relation to those that are less adapted. Considering the tropical regions, it is important to check whether the breeds used have heat tolerance. The aim of this study was to evaluate the heat tolerance of 15 Girolando cows, which was conducted by three evaluations in the months of October, November and December respectively. All evaluations were carried out on sunny days without clouds and little wind. This test consisted of gathering the cows for being compared to each other in a shaded pasture for two hours, from 11 am to 1:00 pm, gauging the physiological parameters at 1:00 pm. Afterwards, the cows were exposed to the open and sunny environment, allowing the total incidence of solar radiation, for one hour (from 1:00 p.m. to 2:00 p.m.), then returning to the shaded corral, being immediately gauging the physiological parameters, and remaining for more one hour, from 2:00 p.m. to 3:00 p.m. assessing again the parameters at 3:00 p.m. The temperature and humidity index found in the evaluations performed at 1:00, 2:00 and 3:00 p.m. hours were 76.6, 77.6 and 78.5, respectively. The mean body surface temperature obtained at 1:00, 2:00 and 3:00 p.m. were 38.16 ° C, 38.90 ° C and 38.22 ° C, respectively. The average values of the sweating rate found were 845.55, 1,088.29 and 955.85 g. m-². h-1 for the measurements performed at 1:00, 2:00 and 3:00 p.m., respectively. The mean values of the rectal temperature obtained at 1:00, 2:00 and 3:00 p.m. were 38.39 ° C, 38.70 ° C and 38.45 ° C, respectively. The evaluated cows showed heat tolerance, suggesting that dairy cattle production systems in the tropics can use Girolando cows.
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Sampaio, Cláudia Batista, Edenio Detmann, Tiago Neves Pereira Valente, Viviane Aparecida Carli Costa, Sebastião de Campos Valadares Filho, and Augusto Cesar de Queiroz. "Fecal excretion patterns and short term bias of internal and external markers in a digestion assay with cattle." Revista Brasileira de Zootecnia 40, no. 3 (March 2011): 657–65. http://dx.doi.org/10.1590/s1516-35982011000300026.

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The objective of this work was to evaluate the fecal excretion profile and the short term bias of the external markers chromic oxide and titanium dioxide and the internal markers indigestible dry matter (iDM), indigestible neutral detergent fiber (iNDF) and indigestible acid detergent fiber (iADF) in a digestion trial with cattle fed different diets. Fourteen F1 Red Angus × Nellore bulls averaging 12 months old and 287 kg were kept in individual stalls. The animals were fed elephant grass silage, corn silage or signal grass hay, supplemented or not with 20% of concentrate mixture. The experiment consisted of two 13-day experimental periods according to a 2 × 2 Latin square design with seven squares grouping. The animals received 10 g of chromic oxide and 10 g of titanium dioxide through esophageal sounder daily. Fecal grab samples were obtained directly from the rectum of the animals at 1:30 a.m., 3:00 a.m., 4:30 a.m., 6:00 a.m., 7:30 a.m., 9:00 a.m., 10:30 a.m., 12:00 p.m., 1:30 p.m., 3:00 p.m., 4:30 p.m., 6:00 p.m., 7:30 p.m., 9:00 p.m., 10:30 p.m. and 12:00 a.m. There was no effect of forages or concentrate levels on the dimension of excretory cycle. The fundamental period of excretory cycle was 15.06 and 18.66 hours for chromic oxide and titanium dioxide, respectively and 9.93, 9.29 and 10.55 hours for iDM, iNDF and iADF, respectively. The oscillation range was higher for external markers. Considering the characteristics of all evaluated markers together, it is recommended fecal sampling designs with at least four collections, distributed during the day or only in the diurnal period for obtaining fecal excretion estimates free of short term bias.
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Nikbakhtian, Shahram, Angus B. Reed, Bernard Dillon Obika, Davide Morelli, Adam C. Cunningham, Mert Aral, and David Plans. "Accelerometer-derived sleep onset timing and cardiovascular disease incidence: a UK Biobank cohort study." European Heart Journal - Digital Health 2, no. 4 (November 9, 2021): 658–66. http://dx.doi.org/10.1093/ehjdh/ztab088.

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Abstract Aims Growing evidence suggests that poor sleep health is associated with cardiovascular risk. However, research in this area often relies upon recollection dependent questionnaires or diaries. Accelerometers provide an alternative tool for measuring sleep parameters objectively. This study examines the association between wrist-worn accelerometer-derived sleep onset timing and cardiovascular disease (CVD). Methods and results We derived sleep onset and waking up time from accelerometer data collected from 103 712 UK Biobank participants over a period of 7 days. From this, we examined the association between sleep onset timing and CVD incidence using a series of Cox proportional hazards models. A total of 3172 cases of CVD were reported during a mean follow-up period of 5.7 (±0.49) years. An age- and sex-controlled base analysis found that sleep onset time of 10:00 p.m.–10:59 p.m. was associated with the lowest CVD incidence. An additional model, controlling for sleep duration, sleep irregularity, and established CVD risk factors, did not attenuate this association, producing hazard ratios of 1.24 (95% confidence interval, 1.10–1.39; P &lt; 0.005), 1.12 (1.01–1.25; P = 0.04), and 1.25 (1.02–1.52; P = 0.03) for sleep onset &lt;10:00 p.m., 11:00 p.m.–11:59 p.m., and ≥12:00 a.m., respectively, compared to 10:00 p.m.–10:59 p.m. Importantly, sensitivity analyses revealed this association with increased CVD risk was stronger in females, with only sleep onset &lt;10:00 p.m. significant for males. Conclusions Our findings suggest the possibility of a relationship between sleep onset timing and risk of developing CVD, particularly for women. We also demonstrate the potential utility of collecting information about sleep parameters via accelerometry-capable wearable devices, which may serve as novel cardiovascular risk indicators.
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Paul, Rajendra D. "Foot Swelling in VDT Operators with Sitting and Sit-Stand Workstations." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 39, no. 10 (October 1995): 568–72. http://dx.doi.org/10.1177/154193129503901006.

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In a controlled field study, effect of sit-stand workstations on foot swelling during the course of a workday was monitored in visual display terminal (VDT) operators. Six VDT operators first worked in offices furnished with nonadjustable sitting workstations. Then they worked in offices furnished with sit-stand adjustable furniture for six weeks. In the later setting, they stood for 15 minutes every hour. In both settings, the foot swelling was measured at 8 a.m., 12 p.m., 1 p.m. and 5 p.m. using a foot volumeter. Between 12 p.m. and 1 p.m., subjects walked for 20 minutes and sat for 40 minutes. The results showed that the average right foot swelling in offices with sit-stand adjustable furniture was significantly less than that in offices with nonadjustable furniture, 12.3 ml (1.1 percent) compared to 21 ml (1.8 percent). These results suggest that activity promoted using sit-stand workstations benefits sedentary office workers.
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Guntama, Dody, Ayu Lintang Cahyani, Vidrika Linda, and Sari Sekar Ningrum. "ALOHA Simulation to Determine Consequence Scenarios on Transportation Liquefied Natural Gas (LNG) in DKI Jakarta Province." Journal of Community Based Environmental Engineering and Management 6, no. 2 (September 26, 2022): 49–58. http://dx.doi.org/10.23969/jcbeem.v6i2.5924.

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The mobility of using LNG is based on its advantages as a substituent fuel for gasoline and diesel, where LNG has low emission properties. The process of mobilizing the distribution of LNG has the potential for accidents when it takes place. The study was conducted to determine the hazards that can occur and the safe distance for evacuation in the event of a leak using ALOHA simulation. The research process is carried out by studying literature, collecting data, determining the month and time of release, and continuing with a simulation of the existing data. The data analysis technique was carried out by determining the tank temperature and water dispersion model at 31 SPBG. Fireball simulation results at 8:00 a.m. 2:00 p.m, and 10:00 p.m have safe distances at 812 meters, 812 meters, and 815 meters. Fire column simulation results at 8:00 a.m. 2:00 p.m, and 10:00 p.m have safe distances at 29 meters, 29 meters, and 28 meters. Vapor cloud simulation results at 8:00 a.m. 2:00 p.m, and 10:00 p.m have Lower Explosive Limits (LEL) at 169 meters, 160 meters, and 243 meters. Thus the ALOHA simulation can represent the safe distance of evacuation and scenarios in the event of an accident.
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Eduard, Rudy, Wegie Ruslan, Isdaryanto Iskandar, and Djoko Setyanto. "Setting Temperature and Humidity with a Misting System in a Pilot Greenhouse at Cisauk-Tangerang, Indonesia." Applied Sciences 12, no. 18 (September 14, 2022): 9192. http://dx.doi.org/10.3390/app12189192.

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A modern agricultural method of cultivating mustard greens and watercress with a hydroponic system in a pilot greenhouse has been implemented by a group of farmers in Cisauk-Tangerang, Banten, Indonesia. The characteristic tropical climate south of the equator causes high temperatures and humidity in the greenhouse. This study aims to control the temperature and humidity in the greenhouse using the misting method so that the temperature and humidity are not more than 33 °C and 85%, respectively. A misting system designed by the main equipment consists of a water flow control pump, temperature and humidity sensors, water mist spray nozzles, and water flow settings for intermittent drizzle for five minutes ON and ten minutes OFF using the internet of things module program. In addition to setting the water discharge intermittently, another limitation for the pump to be OFF is a minimum temperature benchmark of 28 °C and a maximum humidity of 85%. The temperature does not exceed 33 °C, and the humidity setting of 85% is obtained by adjusting the mass flow of water during the day according to the time sequence from 7 a.m. to 5 p.m.: 7 a.m. to 8 a.m. using 50 L/h, 8 a.m. to 10 a.m. using 60 L/h, 10 a.m. to 11 a.m. using 100 L/h, 11 a.m. to 1 p.m. using 120 L/h, 1 p.m. to 2 p.m. using 80 L/h, 2 p.m. to 3 p.m. using 60 L/h, and 3 p.m. and after using 0 L/h or the misting system is turned off.
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Costa, Olívia Bueno da, Cláudio Henrique Soares Del Menezzi, Luiz Eduardo Celino Benedito, Inês Sabioni Resck, Roberto Fontes Vieira, and Humberto Ribeiro Bizzo. "Essential Oil Constituents and Yields from Leaves ofBlepharocalyx salicifolius(Kunt) O. Berg andMyracrodruon urundeuva(Allemão) Collected during Daytime." International Journal of Forestry Research 2014 (2014): 1–6. http://dx.doi.org/10.1155/2014/982576.

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The purpose of this study was to evaluate the essential oil composition and yield from leaves of two Brazilian species (Myracrodruon urundeuvaandBlepharocalyx salicifolius) harvested during daytime. Essential oils were obtained by steam distillation and had their yield determined.Blepharocalyx salicifoliuspresented yields of 0.049% (9 a.m.), 0.045% (1 p.m.), and 0.069% (5 p.m.). ForMyracrodruon urundeuva, we found 0.13% (9 a.m.), 0.11% (1 p.m.), and 0.08% (5 p.m.). Finally, compound identification and quantification were carried out by GC-MS and GC-FID techniques, respectively. Thirteen major compounds were identified forBlepharocalyx salicifolius, representing 91.6% of the EOs, of whichp-cymene (25.9%) was detected as amajor component. Nine major compounds were identified forMyracrodruon urundeuva, representing 90.3% of the EOs, whereasβ-myrcene showed the greatest concentration (66.4%).
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Butterworth, Diane E., David C. Nieman, Janice V. Butler, and Jodi L. Herring. "Food Intake Patterns of Marathon Runners." International Journal of Sport Nutrition 4, no. 1 (March 1994): 1–7. http://dx.doi.org/10.1123/ijsn.4.1.1.

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A group of marathon runners (290 males, 54 females, mean age 39.7 ± 0.7 years) who participated in the Los Angeles Marathon recorded their food and fluid intake throughout a 3-day period, with the time of day denoted for each entry. Investigators coded each subject's food intake according to six time periods: 5:OO-8:59 a.m., 9:00-1059 a.m., 11:OO a.m.-1:59 p.m., 2:00-359 p.m., 4:0&7:59 p.m., and 8:00 p.m.459 a.m. The average intake of the runners consisted of 314 ± 6 g (52.3%) carbohydrates, 83.2 + 2.0 g (30.7%) fat, and 99.7 ± 2.3 g (16.5%) protein. Time periods for breakfast (13.7%), lunch (23.8%), and supper (34.0%) accounted for 71.5% of total caloric intake, with snack time periods contributing 28.5%. Breakfast calories were 68.9 ± 0.9% carbohydrate and 20.4 + 0.7% fat in contrast to supper calories, which were 47.7 ± 0.8% and 31.8 ± 0.6%, respectively. A sizable proportion of the daily caloric intake of recreational marathon runners is contributed by snacks and food intake after 4:00 p.m.
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Tzira, Despoina, Anargyroula Prezerakou, Ioannis Papadatos, Artemis Vintila, Anastasia Bartzeliotou, Filia Apostolakou, Ioannis Papassotiriou, and Vassiliki Papaevangelou. "Salivary biomarkers may measure stress responses in critically ill children." SAGE Open Medicine 6 (January 2018): 205031211880245. http://dx.doi.org/10.1177/2050312118802452.

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Objective: Measurement of salivary biomarkers can provide important information regarding hypothalamic–pituitary–adrenal axis activity both under normal conditions as well as in response to psychological or physical stress. Our aim was to correlate salivary stress markers, such as cortisol, α-amylase and immunoglobulin A, with the Pediatric Risk Index Score of Mortality, underlying disease (pathologic, trauma and postoperative), need for mechanical ventilation/sedation and time lag between onset of illness and admission in children admitted in the pediatric intensive care unit. Methods: We enrolled 79 pediatric intensive care unit patients (2–14 years) over a 2-year period, which satisfy the including criteria, but finally salivary biomarkers were evaluated in 65 patients. Saliva samples were collected within 24 h of admission at 8 a.m., 2 p.m. and 8 p.m. to examine potential disruption of circadian rhythm. Results: Overall, the salivary biomarkers were increased; specifically, median values were (a) cortisol at 8 a.m.: 50.04 nmol/L, 2 p.m.: 30.69 nmol/L and 8 p.m.: 247.12 nmol/L; (b) α-amylase: at 8 a.m.: 22.567 U/L; 2 p.m.: 22.702 U/L and 8 p.m.: 21.484 U/L and (c) IgA at 8 a.m.: 95.10 mg/dL, 2 p.m.: 88.55 mg/dL and 8 p.m.: 80.80 mg/dL. Significantly higher levels were demonstrated in children younger than 6 years and those with Pediatric Risk Index Score of Mortality ⩾8 upon admission. Disturbances in circadian rhythm were observed. Cortisol circadian rhythm disturbance was observed only in children with Pediatric Risk Index Score of Mortality score ⩾8 upon admission while maintaining normal α-amylase circadian rhythm, which was associated with less than 3 days hospitalization in pediatric intensive care unit. No daily variance in IgA was observed. Conclusion: Salivary biomarkers may serve, in critically ill children, as a sensitive, non-invasive method, important for the early recognition of those at high risk and guiding intervention, before clinical deterioration, promoting the quality of health care in pediatric population.
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Barnier, V. M. H., E. Wiklund, A. Van Dijk, F. J. M. Smulders, and G. Malmfors. "Proteolytic enzyme and inhibitor levels in reindeer (Rangifer tarandus tarandus L.) vs. bovine longissimus muscle, as they relate to ageing rate and response." Rangifer 19, no. 1 (April 1, 1999): 13. http://dx.doi.org/10.7557/2.19.1.290.

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<p>Eight reindeer bulls (age 1.5 years) and six Friesian bulls (age 1.5 years) were included in the study for comparison of tenderness. The reindeer were slaughtered at a commercial reindeer slaughter plant in northern Sweden and the Friesian bulls at a commercial slaughter plant in The Netherlands. Samples for determination of calpain/calpastatin activity were taken from the M. longtssimus (LO) within 1 h post mortem (p.m.), and at various times p.m. pH and temperature were registered in LO; ultimate pH values were measured at 24 h p.m. for beef and at 35 h p.m. for reindeer. At day 1 p.m., samples of LO from both carcass sides were excised, divided in two parts, vacuum packaged and stored at 0-2 &deg;C. One part of each muscle was randomly sampled at 1, 3, 7 and 14 days p.m. for determination of shear force, proteolytic enzyme activity, myofibrillar protein degradation, collagen content and heat solubility. pH and temperature fall was faster in reindeer than in beef. Collagen content in reindeer muscle was found to be low but collagen was 4 times less soluble as compared with beef. Reindeer LO was found to be extremely tender, at 3 days p.m. shear force values were only 2-3 kg/cm2 (8-12 kg/cm2 for beef LO). In reindeer meat, the jJ.-calpain levels dropped to about 55% within 3 days. Troponin T and 30 kDa values were not related to changes in tenderness in reindeer meat. Cathepsin activities in reindeer were up to ten times higher than in beef. As in beef, cathepsin B+L levels in reindeer increased during storage, which is probably associated with a decrease in cystatin-like inhibitor levels.</p>
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Ahmad Halili, Ummi Zulaikha, Nor Azam Ramli, and Nur Baitul Izati Rasli. "COMPLIANCE OF THERMAL COMFORT PARAMETERS WITHIN THE STUDENTS’ DORMITORY, RESIDENTIAL, AND PUSAT ISLAM ENGINEERING CAMPUS, USM BASED ON INDUSTRY CODE OF PRACTICE ON INDOOR AIR QUALITY (ICOP) 2010." International Journal of Engineering Technologies and Management Research 9, no. 9 (September 12, 2022): 17–32. http://dx.doi.org/10.29121/ijetmr.v9.i9.2022.1222.

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This study assessed occupants’ satisfaction with their surrounding temperature conditions. The study was carried out at the student’s dormitory, residential and prayer hall of Pusat Islam Engineering Campus, USM. It entailed determining the compliance of thermal comfort parameters; temperature (T), relative humidity (RH) and air movement (AM). The parameters are then used as input in the Center for the Built Environment (CBE) Thermal Comfort Tool to obtain Predicted Mean Value (PMV) and Predicted Percentage Dissatisfied (PPD) for ASHRAE Standard-55. The monitoring for this study was conducted for three hours in a three-time period; 6 A.M. - 9 A.M., 11 A.M. - 2 P.M., and 5 P.M. - 8 P.M. for students’ dormitory and residential. For monitoring at Pusat Islam, it was conducted in two slots; 11 A.M. - 2 P.M. and 6 P.M. - 10 P.M., and it was assessed during Ramadan when the Muslims perform the Teraweh prayer. Overall, the finding indicates that most of the time, the thermal comfort parameters at the three monitoring places did not comply with the (Industry Code of Practice on Indoor Air Quality) ICOP limit. Hence, it also influenced the PMV and PPD values which did not adhere to the ASHRAE Standard-55. This could be due to the poor design of the building where the plan itself does not promote cross-ventilation, the high outdoor temperature, and insufficient indoor air movement, thus causing discomfort to the occupants
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Drago, Filippo, Giuseppe Continella, Orazio Mangano, Pier Luigi Canonico, Renato Bernardini, and Umberto Scapagnini. "Neuroendocrine and Behavioral Effects of Flunarizine in Young and Old Rats." Cephalalgia 5, no. 2_suppl (May 1985): 125–29. http://dx.doi.org/10.1177/03331024850050s223.

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Neuroendocrine and behavioral effects following an acute or chronic treatment with the calcium antagonist, flunarizine, have been studied in young and old rats. Both in young and old rats, acute administration of flunarizine (2 mg/kg) failed to modify plasma prolactin (PRL) levels, as measured at 8.00 a.m., 4.00 p.m. and 12.00 p.m. A chronic treatment with flunarizine (0.5 mg/kg/day, for 20 days) in young rats was followed by a relevant, albeit statistically not significant, increase in plasma PRL levels, as measured at 8.00 a.m. and 4.00 p.m., and by a significant decrease at 12.00 p.m. A shift of nocturnal peak of plasma PRL levels from 12.00 p.m. to 4.00 a.m. was observed in these animals. A chronic treatment with flunarizine in old rats was followed by a significant increase in plasma PRL levels, as measured at 12.00 p.m. The acquisition of active avoidance behavior was studied in a shuttle-box test. Acute administration of flunarizine failed to change the performance of young and old rats in acquiring the behavioral response, as measured by the total number of conditioned avoidance responses (CARs) and the percentage of learners. When flunarizine was administered chronically, a decrease in CARs and learners was observed both in young and old rats. This was accompanied by a significant increase in the percentage of animals that froze during the acquisition session. No significant effect was found in young and old rats tested in a “despair” test after a chronic treatment with flunarizine.
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Baek, Jieun, and Yosoon Choi. "An Experimental Study on Performance Evaluation of Shading Matrix to Select Optimal Parking Space for Solar-Powered Electric Vehicles." Sustainability 14, no. 22 (November 11, 2022): 14922. http://dx.doi.org/10.3390/su142214922.

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This study evaluated the applicability of a shading matrix generated using hemispherical fisheye images to select the optimal parking space to maximize the photovoltaic (PV) power generation of solar electric vehicles. The study aims to identify the maximum power point (MPP) of a PV module in a parking space using current–voltage measuring equipment to determine whether the shading matrix reflects any shadow phenomenon. The experiment was conducted on a parking lot at Daeyeon Campus. The fisheye images were taken in seven parking spaces. The shading matrices were generated by tracking the position of the sun over 12 months and 24 h periods. A 50 W PV module was installed on the roof of the vehicle and the MPP was measured in five experiments (9 a.m., 11 a.m., 13 p.m., 15 p.m., and 17 p.m.) in seven parking spaces. In parking spaces with a shading factor of 0, the PV modules were not shaded at all during the experiment, and the average MPPs were 34, 43, 37, and 21 W at 9 a.m., 11 a.m., 13 p.m., and 15 p.m., respectively. The shading matrix calculated using the fisheye images accurately reflected the shadow phenomenon that decreases PV power generation.
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Milius, Susan. "A.M. and P.M. Clocks." Science News 166, no. 16 (October 16, 2004): 244. http://dx.doi.org/10.2307/4015830.

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Harding, Katharine, and Clinton Mitchell. "The 10 p.m. Question." Practical Neurology 17, no. 2 (February 14, 2017): 168. http://dx.doi.org/10.1136/practneurol-2017-001594.

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Norwich, Diana, Nishitha Kotla, and Kjersti Kirkeby. "PSAT388 A Rapidly progressive papillary thyroid carcinoma presenting 22 years after RAI therapy." Journal of the Endocrine Society 6, Supplement_1 (November 1, 2022): A850. http://dx.doi.org/10.1210/jendso/bvac150.1757.

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Abstract The risk of thyroid cancer following RAI therapy remains controversial. We report a case of an aggressive papillary thyroid carcinoma presenting over twenty years after RAI therapy for Graves’ disease. Presentation: Saturday, June 11, 2022 1:00 p.m. - 3:00 p.m.
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Pierangeli, D., M. Flammini, G. Marcucci, A. J. Agranat, P. G. Grinevich, P. M. Santini, C. Conti, and E. DelRe. "ОBSERVATION OF FERMI-PASTA-ULAM-TSINGOU RECURRENCE IN OPTICAL EXPERIMENT." XXII workshop of the Council of nonlinear dynamics of the Russian Academy of Sciences 47, no. 1 (April 30, 2019): 107–8. http://dx.doi.org/10.29006/1564-2291.jor-2019.47(1).32.

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Recently P.G. Grinevich and P.M. Santini suggested simple approximate formulas for solving periodic Cauchy problem for the focusing Nonlnear Schrodinger Equation (NLS) under assumption that one starts from a small perturbation of the unstable condensate and the number of unstable modes is not too large. With the help of these results, optical experiments in photorefractive crystal where conducted, in which the second and third return of anomalous waves was observed. A good agreement between the experimental data and the predictions made on the basis of the NLS theory was obtained. P.G. Grinevich was supported by the Russian Science Foundation grant No. 18-11-00316.
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Tharu, Nanda Kumar, and Yogesh Man Shrestha. "An Overview of the Trends of Road Accidents and Indices in Nepal." NUTA Journal 8, no. 1-2 (December 31, 2021): 94–102. http://dx.doi.org/10.3126/nutaj.v8i1-2.44107.

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This paper discusses the current state of accidents with reference to variety of factors. Of years 2068 to 2076, secondary data was picked up from Kathmandu's metropolitan traffic police division. Trend and Statistical Analysis has been used. Seasonal indices has been calculated to examine time-effect on accidents rate. Numerous element were responsible to road accidents that contributes to the occurrence of accidents in its own way, and there may be many additional situation-specific factors untapped. However, the bulk of road traffic accidents have been seen in drivers age between 21 to 40, types of vehicles reported on accidents were motorcycles, scooters, tractors, and tempos, and , time between the hours of 6 p.m. and 12 a.m. Similarly, male pedestrians and motorcyclists/scooters had a higher rate of fatality. The hours of 12 p.m. to 6 p.m. had 17.8 percent more accidents than average, and the hours of 6 p.m. to 12 a.m. had a 68.15 percent higher chance of an accident.
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Zhuo, Shao Ming, Jia Xie, Chun Yuan Wu, and Guang Yi Li. "Preliminary Experiment on Extraction of Eisenia foetida Coelomic Fluid with Water Bath Pot." Advanced Materials Research 610-613 (December 2012): 3566–69. http://dx.doi.org/10.4028/www.scientific.net/amr.610-613.3566.

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This work explored a new water bath stimulating method to extract coelomic fluid from active Eisenia foetida. Coelomic fluid discharge amount and the coelomic fluid activity were tested to obtain the optimum extraction temperature (ET) and time. The maximum amount of coelomic fluid was obtained at 42 oC, at which vermis is exact activity, while the vermis activity is inhibited at 44 oC and even the vermis comprehensive death is observed at 46 oC, therefore the optimum ET is 42 oC; the optimum extraction time is 7 a.m. and 6 p.m for which the volume of coelomic fluid is the most. When extracted from coelomic fluid at 7 a.m and 11a.m, 60 times and 10 times diluted solution obtained the highest generation rate; when it is at 3 p.m., 10 and 100 dilution times is the best; when it is at 1 p.m., 30 and 200 dilution times is the best, and 30-80 dilution times is the optimal when it is from 3 p.m..
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K. Poudel, Prabin, Binaya Baral, Richa Shah, Rajkumar K.C, and N. B. Singh. "STUDY OF FORAGING BEHAVIOR OF APIS CERANA DURING SUMMER IN SUNDARBAZAR, LAMJUNG, NEPAL." Big Data In Agriculture 4, no. 2 (2022): 54–57. http://dx.doi.org/10.26480/bda.02.2022.54.57.

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Apis cerana forages for around 10 hours/day, starting early in the morning and ending late at night. A study was undertaken in an apiary in Sundarbazar, from March-May 2021 to measure the foraging activity. At 8a.m, 11a.m, 1p.m, and 4p.m, number of bees leaving and entering hives with and without pollen for a minute in four different beehives were recorded. According to the observation, there was a significant difference in bee behavior (P0.01) between the time treatments. Pollen-carrying bees entered the hive in greater numbers at 1 p.m, 11 a.m, which was statistically equal to 4 p.m, and least at 8 a.m. Similarly, at 1 p.m., the number of bee leaving and entering the hive without pollen was much greater, followed by 11 a.m. which was statistically equivalent to 4 p.m, and 8 a.m, which had the least. The highest mean value of bee movement was found in May.
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Hacker-Klom, Ursula Beate. "Diurnal Changes in Murine Spermatogenesis." Zeitschrift für Naturforschung C 49, no. 7-8 (August 1, 1994): 522–25. http://dx.doi.org/10.1515/znc-1994-7-820.

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We analysed testicular samples of NMRI mice every 2 h of a day in order to determine whether there is a circadian rhythm in spermatogenetic activity. We used flow cytometry after staining the DNA with DAPI. The highest proportion of DNA synthesizing cells (mainly spermatogonia and preleptotene spermatocytes) was seen at 8 p.m. and especially at 10 p.m.; the lowest proportion was observed at 2 p.m. At 6 a.m., the percentage of round spermatids increased significantly, whereas the fraction of 4c-cells decreased at that time. Our results of a diurnal rhythm of spermatogenic DNA synthesis rate are in contrast to another publication of other authors (Oakberg and Crosswait, 1983)
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Chait Barnett, Rosalind, Karen C. Gareis, and Robert T. Brennan. "Wives' Shift Work Schedules and Husbands' and Wives' Well-Being in Dual-Earner Couples With Children." Journal of Family Issues 29, no. 3 (November 19, 2007): 396–422. http://dx.doi.org/10.1177/0192513x07305346.

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In a sample of 55 dual-earner families with children aged 8 to 14 in which the mothers are registered nurses regularly working either day shifts (typically 7:00 a.m. to 3:00 p.m.) or evening shifts (typically 3:00 p.m. to 11:00 p.m.), we estimated the within-couple relationship between the wife's work variables (i.e., work shift, work hours, and the interaction between work shift and work hours) and each spouse's work—family conflict, psychological distress, and marital-role quality. Wives' work variables predicted their own work—family conflict and psychological distress and showed a trend to predict their husbands' work—family conflict.
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Even, Paula. "Sigma Gamma Epsilon Student Research Poster Session, Geological Society of America Meeting 2013, Denver, Colorado." Compass: Earth Science Journal of Sigma Gamma Epsilon 85, no. 4 (March 10, 2014): 140–57. http://dx.doi.org/10.62879/c93248923.

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The 2013 Sigma Gamma Epsilon Undergraduate Research (Poster Session) took place during the 2013 GSA Conference in Denver, CO. on Tuesday, 29 October 2013: 9:00 a.m. - 6:30 p.m. (Authors were present from 2 to 4 p.m. and 5:00 to 6:30 p.m.). Ninety-eight posters were presented. Sigma Gamma Epsilon awarded the Austin A. Sartin Best Poster Award to Brittney Klemm, a member of Eta Upsilon Chapter at the University of the Pacific in Stockton, CA. Sebastian Dirringer, a member of Theta Beta Chapter at the State University of New York in New Paltz, NY, was awarded the National Council Best Poster Award.
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Coomber, Kerri, Peter G. Miller, Jessica J. Killian, Rowan P. Ogeil, Naomi Beard, Dan I. Lubman, Ryan Baldwin, Karen Smith, and Debbie Scott. "Description of Trends over the Week in Alcohol-Related Ambulance Attendance Data." International Journal of Environmental Research and Public Health 20, no. 8 (April 19, 2023): 5583. http://dx.doi.org/10.3390/ijerph20085583.

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Alcohol harms are often determined using a proxy measure based on temporal patterns during the week when harms are most likely to occur. This study utilised coded Australian ambulance data from the Victorian arm of the National Ambulance Surveillance System (NASS) to investigate temporal patterns across the week for alcohol-related ambulance attendances in 2019. These patterns were examined by season, regionality, gender, and age group. We found clear temporal peaks: from Friday 6:00 p.m. to Saturday 3:59 a.m. for both alcohol-involved and alcohol-intoxication-related attendance, from Saturday 6:00 p.m. to Sunday 4:59 a.m. for alcohol-involved attendances, and from Saturday 5:00 p.m. to Sunday 4:49 a.m. for alcohol-intoxication-related attendances. However, these temporal trends varied across age groups. Additionally, hours during Thursday and Sunday evenings also demonstrated peaks in attendances. There were no substantive differences between genders. Younger age groups (18–24 and 25–29 years) had a peak of alcohol-related attendances from 7:00 p.m. to 7:59 a.m. on Friday and Saturday nights, whereas the peak in attendances for 50–59 and 60+ years was from 5:00 p.m. to 2:59 a.m. on Friday and Saturday nights. These findings further the understanding of the impacts of alcohol during different times throughout the week, which can guide targeted policy responses regarding alcohol use and health service capacity planning.
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DEVALEENAL, DANIEL BELLA, LAVANYA JEYABAL, DINA NAIR, VASANTHA MAHALINGAM, RADHAKRISHNAN R, BINNY PRISCILLA REBECCA, CHANDRA SURESH, PARANCHI RAMESH MURUGESAN, and BEENA THOMAS. "Improving treatment adherence among tuberculosis patients through evening DOTS in Chennai, India." National Medical Journal of India 36 (March 11, 2024): 219–23. http://dx.doi.org/10.25259/nmji_819_20.

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Background Fixed days and timings of service are challenges in the care of patients with tuberculosis (TB). We assessed whether provision of evening DOTS (directly observed treatment, short course) improves treatment outcomes in a city with a working population. Methods We enrolled new adult patients with TB from seven tuberculous units (TUs) in this prospective cohort study. Participants were offered the option of DOTS during the day (8 a.m. to 3:30 p.m.) or evening (4 p.m. to 8 p.m.) and assigned accordingly. Results Of 127 patients enrolled between April and July 2017, 19 (15%) opted for evening DOTS. The number varied between the seven TUs (p=0.002). On an average, antitubercular therapy (ATT) was taken at 9:41 a.m. in the routine and 5:14 p.m. in the evening DOTS centres. Patients who were employed, left residence and returned back at 9:05 a.m. and 6:40 p.m., respectively. Around 96% (104/108) opted for day-time DOTS due to closeness of the centre to their residence. Around 74% (14/19) chose evening DOTS because of time convenience. Around 15% of patients on routine DOTS (16) had unfavourable treatment outcomes. All had favourable outcomes in the evening DOTS. Men were less likely and those withut alcohol disorders were more likely to have treatment success. Conclusion Provision of time convenient services might improve adherence and treatment outcome.
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41

Londoño-Paéz, Sandra Milena, Jose Alfredo Orjuela-Chaves, Faver Álvarez-Carrillo, Juan Carlos Suarez-Salazar, Lucena Vasquez-Gamboa, Jhoyner Felipe Ortiz-Meneses, and Gustavo Adolfo Celis Parra. "Ethological behavior of Bos taurus, Bos indicus, and Caqueteño Creole cattle in three tree cover systems of Brachiaria decumbens paddocks at the Amazon foothills in Colombia." Revista de Ciências Agroveterinárias 21, no. 2 (March 25, 2022): 148–58. http://dx.doi.org/10.5965/223811712122022148.

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The study was conducted at the Amazon Research Center CIMAZ - MACAGUAL of the University of Amazonia, Colombia, with a tropical rain forest climate (Af). The behavior of Bos taurus, Bos indicus, and Caqueteño Creole cattle, the animals were observed in paddocks with three levels of scattered tree cover density. The pasture was composed of Braquiaria decumbens with 35 days of regrowth. Direct observations were made from 9:00 a.m. to 5:00 p.m. with 10-minute intervals between the recording of the activities. The activity performed most often during the day by all of the animals was grazing under the sun, and those who pasture the most are the Caqueteño Creole, followed by the Bos indicus and, finally, the Bos taurus. Ruminating was the second most important activity performed by the cattle, having presented the same tendency. In the paddocks with a low level of tree cover, the animals pasture more in the shade; this trend is more relevant among B. taurus cattle. Caqueteño Creole cattle dedicate less time to water consumption and rest, spending more time grazing, in the high and medium cover levels, they interrupt the grazing at noon for a shorter time compared to B. indicus and B. taurus; after 2 p.m., the creoles vertiginously increase grazing. At the high cover level, the peak of grazing of the Caqueteño Creoles is at 9 a.m. and from 1-1:30 p.m., while at the medium tree cover level, the peak of pasturing was at noon, 1:30 p.m., and 4:30 p.m., at the high tree level of cover, the peak for the three breeds was at 11 a.m. Only at the average tree level of cover did the Caquetaño creoles and B. indicus present a similar peak. In 9-9:30 a.m. and 4-5 p.m., the breeds substantially reduce rumination.
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Domiciano, L. F., M. A. Mombach, P. Carvalho, N. M. F. da Silva, D. H. Pereira, L. S. Cabral, L. B. Lopes, and B. C. Pedreira. "Performance and behaviour of Nellore steers on integrated systems." Animal Production Science 58, no. 5 (2018): 920. http://dx.doi.org/10.1071/an16351.

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This study aimed to evaluate performance and behaviour of Nellore steers (Bos taurus indicus) in integrated systems. Treatments consisted of three different systems: livestock; crop-livestock; and livestock-forestry, with triple rows of eucalyptus trees. The experiment was carried out in Sinop, MT, Brazil, in a randomised complete block design with four replicates, during two seasons (dry-rainy transition and rainy). The experimental period was from 19 September 2015 to 10 January 2016. Nellore steers used in the experiment had an average initial weight of 344 kg ± 11 kg, in continuous stocking and variable stocking rate. Forage mass accumulation rate was evaluated and, independently of the system, had the highest values recorded during the rainy season. Microclimate was evaluated through temperature and humidity index, black globe temperature and humidity index and radiant heat load. Highest values were obtained from 11:00 a.m. to 3:00 p.m. at the dry-rainy transition period for all systems. Animal behaviour was assessed every 10 min from 7:00 a.m. to 5:00 p.m., and averages were calculated for every 2 h. The longest grazing period was recorded from 9:00 a.m. to 1:00 p.m., and then after 3:00 p.m., regardless of the system. Rumination occurred more frequently from 1:00 p.m. to 3:00 p.m. during the rainy season, and also in the shade for the livestock-forestry system. Highest weight gains per area were recorded during the rainy season and for the crop-livestock system. It is concluded that the highest yields can be achieved with the inclusion of the crop component in livestock production systems, and that Nellore steers in silvopastoral systems prefer to ruminate and stay idle in the shade.
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43

Maher, Jaclyn P., Eldin Dzubur, Jimi Huh, Stephen Intille, and Genevieve F. Dunton. "Within-Day Time-Varying Associations Between Behavioral Cognitions and Physical Activity in Adults." Journal of Sport and Exercise Psychology 38, no. 4 (August 2016): 423–34. http://dx.doi.org/10.1123/jsep.2016-0058.

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This study used time-varying effect modeling to examine time-of-day differences in how behavioral cognitions predict subsequent physical activity (PA). Adults (N = 116) participated in three 4-day “bursts” of ecological momentary assessment (EMA). Participants were prompted with eight EMA questionnaires per day assessing behavioral cognitions (i.e., intentions, self-efficacy, outcome expectations) and wore an accelerometer during waking hours. Subsequent PA was operationalized as accelerometer-derived minutes of moderate- or vigorousintensity PA in the 2 hr following the EMA prompt. On weekdays, intentions positively predicted subsequent PA in the morning (9:25 a.m.–11:45 a.m.) and in the evening (8:15 p.m.–10:00 p.m.). Self-efficacy positively predicted subsequent PA on weekday evenings (7:35 p.m.–10:00 p.m.). Outcome expectations were unrelated to subsequent PA on weekdays. On weekend days, behavior cognitions and subsequent PA were unrelated regardless of time of day. This study identifies windows of opportunity and vulnerability for motivation-based PA interventions aiming to deliver intervention content within the context of adults’ daily lives.
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Krebs, Nancy F., K. Michael Hambidge, Margaret A. Jacobs, and Sheila Mylet. "Zinc in Human Milk." Journal of Pediatric Gastroenterology and Nutrition 4, no. 2 (April 1985): 227–29. http://dx.doi.org/10.1002/j.1536-4801.1985.tb08827.x.

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To examine diurnal patterns of milk zinc concentrations, midfeed samples were obtained at approximately 6 a.m., 9 a.m., 12 noon, 3 p.m., 6 p.m., and 9 p.m. on a total of 29 days from 16 lactating women. Within‐feed patterns were examined in 32 subjects with analysis of samples of fore‐, mid‐, and hindmilk from a total of 175 feeds. There were no significant differences between means for any of the diurnal intervals or between means for fore‐, mid‐, and hindmilk samples. These results indicate that milk zinc concentrations of random samples of human milk collected at any time of the day or of the feed can be accepted as representative for that day.
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Adeoti, Oluwatomi, Michael Salim, Asim Kichloo, and Hafeez Shaka. "OR11-5 Outcomes and Predictors of 30-day Readmission for Hyperthyroidism: A Nationwide Study." Journal of the Endocrine Society 6, Supplement_1 (November 1, 2022): A800. http://dx.doi.org/10.1210/jendso/bvac150.1655.

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Abstract This retrospective cohort study examines the 30-day readmission rate for patients with hyperthyroidism. Analysis of data from the 2018 Nationwide Readmissions Database exposed factors that affect this rate and described key healthcare quality indices that are associated with these readmissions. Understanding these will help identify areas for improving patient outcomes. Presentation: Sunday, June 12, 2022 12:00 p.m. - 12:15 p.m.
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46

Medvedev, Konstantin A. "P.M. GOLOVACHEV. THE FAR EAST IN THE THOUGHTS OF THE HISTORIAN." RSUH/RGGU Bulletin. Series Political Sciences. History. International Relations, no. 1 (2021): 50–61. http://dx.doi.org/10.28995/2073-6339-2021-1-50-61.

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The author of the article makes an attempt to analyze the views of Russian historian Peter Mikhailovich Golovachev. Those views concerned issues of Russian policy in the Far East in the late 19 th – early 20 th century. The basis of the article is analyzing P.M. Golovachev’s treatise “Russia in the Far East”. The author of the article intends not only to research different aspects of Russian Far Eastern policy raised in that treatise. The analysis of intellectual context has an equal significance. The author makes an attempt to represent specific features of Russian public thought at the turn of the ages. Researching of P.M. Golovachev’s views enables to identify several intellectual transformations concerned Russian society’s visions of the Far East. The author of the article emphasizes that historical knowledge allowed P.M. Golovachev having an unconventional approach to the consideration of issues of interest to the Russian public. The latter was expressed, in particular, in criticism of well-established ideas and concepts. The author concludes arguing that P.M. Golovachev’s work was the great example of the Far East development project. The emergence of such projects became the forerunner of the sphere of knowledge, which later became known as “geopolitics”.
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47

Kawabata, Celso Y., Lindalva de A. de Jesus, Ana Paula V. da Silva, Thiago V. R. de Sousa, and Luis F. B. da Cruz. "Physiological responses of caprines raised under different types of covering." Engenharia Agrícola 33, no. 5 (October 2013): 910–18. http://dx.doi.org/10.1590/s0100-69162013000500003.

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Thermal discomfort inside facilities is one of the factors responsible for low productivity of caprines in the Brazilian Northeast region, because inadequate weather conditions can cause elevated rectal temperature, increased respiratory rate, decreased food ingestion and reduced production. The present paper aimed to study the behavior of physiological thermoregulation of the animals (respiratory rate - RR and rectal temperature - RT) at four different times of the day (8 a.m., 11 a.m., 2 p.m. and 5 p.m.) and their relation to bioclimatic indexes (Temperature Humidity Index - THI, Black Globe Humidity Index - BGHI and Radiant Heat Load - RHL) in order to determine whether the type of covering used in the animals facilities (ceramic covering - CC, asbestos cement covering - AC and straw covering - SC) interferes with the physiology of thermoregulation. The time of data collection was related to the values of environmental and physiological variables. At 2 p.m. it was found the highest values of Radiant Heat Load on the three types of covering. The values of RT and RR were higher at 11 a.m. and 2 p.m., and the straw tile provided better thermal conditions of microclimate for the animals. The increased RR maintained the caprines homeothermy.
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Liu, Xu, Eric Hoffman, and Eric Ortlund. "RF15 | PMON294 Disrupting a Key H-bond Network Drives Glucocorticoid Receptor Gene Suppression Without Off-target Gene Activation for Duchenne Muscular Dystrophy Treatment." Journal of the Endocrine Society 6, Supplement_1 (November 1, 2022): A734—A735. http://dx.doi.org/10.1210/jendso/bvac150.1516.

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Abstract Duchenne muscular dystrophy is a genetic disorder that shows chronic and progressive damage to skeletal and cardiac muscle leading to premature death. Anti-inflammatory corticosteroids targeting the glucocorticoid receptor (GR) are the current standard of care but drive adverse side effects such as deleterious bone loss. Through subtle modification to a steroidal backbone, a recently developed drug, vamorolone, appears to preserve beneficial efficacy but with significantly reduced side effects. We use combined structural, biophysical, and biochemical approaches to show that loss of a receptor-ligand hydrogen bond drives these remarkable therapeutic effects. Moreover, vamorolone uniformly weakens coactivator associations but not corepressor associations, implicating partial agonism as the main driver of its dissociative properties. Additionally, we identify a critical and evolutionarily conserved intramolecular network connecting the ligand to the coregulator binding surface. Interruption of this allosteric network by vamorolone selectively reduces GR-driven transactivation while leaving transrepression intact. Our results establish a mechanistic understanding of how vamorolone reduces side effects, guiding the future design of partial agonists as selective GR modulators with an improved therapeutic index. Presentation: Sunday, June 12, 2022 1:00 p.m. - 1:05 p.m., Monday, June 13, 2022 12:30 p.m. - 2:30 p.m.
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Mohammed, Hisham, and Yahong Wen. "RF03 | PMON289 KLF4 drives estrogen driven tumor heterogeneity in breast cancer." Journal of the Endocrine Society 6, Supplement_1 (November 1, 2022): A731. http://dx.doi.org/10.1210/jendso/bvac150.1508.

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Abstract Whilst hormonal therapies have proved effective in targeting ER positive breast cancer, intrinsic and acquired resistance to therapy has meant that the disease remains deadly. To identify potential drivers of transcriptional and epigenetic heterogeneity in breast cancer, we performed detailed single-cell multi-ome experiments +/- estrogen stimulation. Our results identified that the transcription factor KLF4 is highly associated with heterogeneity in our experimental models. KLF4 is one of four Yamanaka pluripotency factors that can reprogram cells to a stem like state and is also a pioneer factor, that possesses the ability to bind to condensed chromatin. Silencing of KLF4 significantly reduced transcriptional heterogeneity in multiple models. Importantly, we also found that KLF4 acts as a pioneer factor for ER. ER binding, transcriptional activity and chromatin accessibility at ER binding sites were lost upon KLF4 silencing. Using proteomics based interactome profiling, we find multiple other signaling pathway rely on KLF4. Together, our results suggest that KLF4 maintains plasticity in ER+ breast cancer cells and also functions as a pivotal factor for ER to function. Presentation: Saturday, June 11, 2022 1:36 p.m. - 1:41 p.m., Monday, June 13, 2022 12:30 p.m. - 2:30 p.m.
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Ramos, Enrique, Adhikari Swagata, Ramesh Choudhari, Chandrima Das, and Shrikanth Gadad. "RF03 | PMON290 Transcriptional regulation of immune-pathways by chromatin reader ZMYND8 in triple-negative breast cancer." Journal of the Endocrine Society 6, Supplement_1 (November 1, 2022): A891. http://dx.doi.org/10.1210/jendso/bvac150.1844.

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Abstract Zinc Finger transcription factors are crucial in modulating various cellular processes, including inflammation and immune response. Zinc Finger MYND (Myeloid, Nervy, and DEAF-1) type containing 8 (ZMYND8), a putative chromatin reader. We have observed this chromatin reader's unique role in regulating immune genes expression in triple-negative breast cancer (TNBC). TNBC is a very aggressive subtype of breast cancer. It is characterized as a heterogeneous group of tumors defined by the absence of estrogen receptor, progesterone receptor, and overexpression of the human epidermal growth factor receptor 2 gene. Ectopic expression and genetic deletion of ZMYND8 in triple-negative breast cancer cells modulated the expression of several genes implicated in immune response and cancer. Mechanistically, ZMYND8 regulates transcription by epigenetically modulating key promoters of target genes. Collectively our results elucidate a novel role for ZMYND8 in triple-negative cancer biology. This work was supported by grants from the Cancer Prevention and Research Institute of Texas (RR170020) and the Lizanell and Colbert Coldwell Foundation to S.S.G. Presentation: Saturday, June 11, 2022 1:54 p.m. - 1:59 p.m., Monday, June 13, 2022 12:30 p.m. - 2:30 p.m.
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