Academic literature on the topic 'P63RhoGEF'

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Journal articles on the topic "P63RhoGEF"

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Souchet, Michel, Elodie Portales-Casamar, David Mazurais, et al. "Human p63RhoGEF, a novel RhoA-specific guanine nucleotide exchange factor, is localized in cardiac sarcomere." Journal of Cell Science 115, no. 3 (2002): 629–40. http://dx.doi.org/10.1242/jcs.115.3.629.

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The Rho small GTPases are crucial proteins involved in regulation of signal transduction cascades from extracellular stimuli to cell nucleus and cytoskeleton. It has been reported that these GTPases are directly associated with cardiovascular disorders. In this context, we have searched for novel modulators of Rho GTPases, and here we describe p63RhoGEF a new Db1-like guanine nucleotide exchange factor (GEF). P63RhoGEF encodes a 63 kDa protein containing a Db1 homology domain in tandem with a pleckstrin homology domain and is most closely related to the second Rho GEF domain of Trio. Northern
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Bodmann, Eva-Lisa, Andreas Rinne, Dominique Brandt та ін. "Dynamics of Gαq-protein–p63RhoGEF interaction and its regulation by RGS2". Biochemical Journal 458, № 1 (2014): 131–40. http://dx.doi.org/10.1042/bj20130782.

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Blankenbach, Kira Vanessa, Ralf Frederik Claas, Natalie Judith Aster, et al. "Dissecting Gq/11-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1." Cells 9, no. 10 (2020): 2201. http://dx.doi.org/10.3390/cells9102201.

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Diverse extracellular signals induce plasma membrane translocation of sphingosine kinase-1 (SphK1), thereby enabling inside-out signaling of sphingosine-1-phosphate. We have shown before that Gq-coupled receptors and constitutively active Gαq/11 specifically induced a rapid and long-lasting SphK1 translocation, independently of canonical Gq/phospholipase C (PLC) signaling. Here, we further characterized Gq/11 regulation of SphK1. SphK1 translocation by the M3 receptor in HEK-293 cells was delayed by expression of catalytically inactive G-protein-coupled receptor kinase-2, p63Rho guanine nucleo
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Shankaranarayanan, Aruna, Cassandra A. Boguth, Susanne Lutz та ін. "Gαq allosterically activates and relieves autoinhibition of p63RhoGEF". Cellular Signalling 22, № 7 (2010): 1114–23. http://dx.doi.org/10.1016/j.cellsig.2010.03.006.

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Ongherth, Anita, Sebastian Pasch, Christina M. Wuertz, et al. "p63RhoGEF regulates auto- and paracrine signaling in cardiac fibroblasts." Journal of Molecular and Cellular Cardiology 88 (November 2015): 39–54. http://dx.doi.org/10.1016/j.yjmcc.2015.09.009.

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Momotani, Ko, and Avril V. Somlyo. "p63RhoGEF: A New Switch for Gq-Mediated Activation of Smooth Muscle." Trends in Cardiovascular Medicine 22, no. 5 (2012): 122–27. http://dx.doi.org/10.1016/j.tcm.2012.07.007.

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Swenson-Fields, Katherine I., Joshua C. Sandquist, Jessica Rossol-Allison та ін. "MLK3 Limits Activated Gαq Signaling to Rho by Binding to p63RhoGEF". Molecular Cell 32, № 1 (2008): 43–56. http://dx.doi.org/10.1016/j.molcel.2008.09.007.

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Calò, Lorenzo A., Paul A. Davis, Elisa Pagnin, et al. "Increased level of p63RhoGEF and RhoA/Rho kinase activity in hypertensive patients." Journal of Hypertension 32, no. 2 (2014): 331–38. http://dx.doi.org/10.1097/hjh.0000000000000075.

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Calo', Lorenzo A., Verdiana Ravarotto, Elisa Pagnin, Ugo Vertolli, Gianni Carraro, and Giuseppe Maiolino. "FP076EFFECT OF OLMESARTAN MEDOXOMIL ON P63RHOGEF AND RHOA/RHO KINASE ACTIVITY IN HYPERTENSIVE PATIENTS." Nephrology Dialysis Transplantation 30, suppl_3 (2015): iii91. http://dx.doi.org/10.1093/ndt/gfv168.07.

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Calo', Lorenzo A., Verdiana Ravarotto, Elisa Pagnin, Gianni Carraro, and Giuseppe Maiolino. "Effect of olmesartan medoxomil on p63RhoGEF and RhoA/Rho kinase activity in hypertensive patients." Journal of the American Society of Hypertension 9, no. 4 (2015): e19. http://dx.doi.org/10.1016/j.jash.2015.03.045.

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Dissertations / Theses on the topic "P63RhoGEF"

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Pasch, Sebastian. "Analysis of the GPCR-induced RhoA signaling in healthy and diseased adult cardiomyocytes." Doctoral thesis, 2018. http://hdl.handle.net/11858/00-1735-0000-002E-E5FC-7.

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Vettel, Christiane [Verfasser]. "Charakterisierung des Guaninnukleotid-Austauschfaktors p63RhoGEF als neuen Mediator der Gαq/11-induzierten [G-alpha-q/11-induzierten] RhoA-Aktivierung / vorgelegt von Christiane Vettel". 2009. http://d-nb.info/997289392/34.

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Ongherth, Anita. "RhoGTPases and their relevance for the afterload-dependent myocardial fibrosis." Doctoral thesis, 2016. http://hdl.handle.net/11858/00-1735-0000-002B-7CC9-0.

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Book chapters on the topic "P63RhoGEF"

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Meigs, Thomas E., Alex Lyakhovich, Hoon Shim, et al. "GEFT, p63RhoGEF." In Encyclopedia of Signaling Molecules. Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_100535.

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"GEFT, p63RhoGEF." In Encyclopedia of Signaling Molecules. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_101427.

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