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1

United States. Acute Pain Management Guideline Panel. Acute pain management: Operative or medical procedures and trauma. Agency for Health Care Policy and Research, Public Health Service, US Department of Health and Human Services, 1992.

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2

Farrar, John T. Understanding clinical trials in palliative care research. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0193.

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Advances in basic science, translational, and clinical research have led to rapid improvements in our understanding of many disease processes. The randomized clinical trial (RCT) has played an important role in validating the benefits and harms of therapies thought to be potentially useful based on scientific theory or clinical observation, and has become the ‘gold standard’ for the demonstration of efficacy. As in all clinical study designs, the RCT has strengths and weaknesses that must be understood to appropriately interpret the study results. While randomization of the intended study popu
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3

Sabharwal, Tarun, Nicos I. Fotiadis, and Andy Adam. Interventional radiology in the palliation of cancer. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0126.

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Over the past four decades, a variety of invasive diagnostic and therapeutic procedures have been developed by radiologists. The term ‘interventional radiology’ most appropriately refers to therapeutic procedures performed under imaging guidance. Interventional radiological procedures have virtually replaced several more invasive and hazardous surgical alternatives. Other interventional techniques offer completely new therapeutic options. Some diagnostic radiological procedures are frequently followed by therapeutic manoeuvres. Interventional radiology can make a significant contribution to th
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4

Scheunemann, Leslie P., and Robert M. Arnold. Communication with patients and families in the ICU. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0011.

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Regular, consistent communication with families of intensive care unit (ICU) patients is important for family satisfaction, patient-centred decision-making, and reducing the emotional burden of the ICU stay on family members. In fact, the family meeting can appropriately be considered a core procedure of intensive care practice. Good communication requirements include the appropriate clinicians and family members, providing a quiet and undisturbed setting, and choosing appropriate goals for each meeting. Clinicians should strive to develop skills for listening, observing family dynamics, and r
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5

Acute pain management in adults: Operative procedures. Executive Office Center, Agency for Health Care Policy and Research, Public Health Service, Dept. of Health and Human Services, 1992.

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6

Wilkinson, Ian B., Tim Raine, Kate Wiles, Anna Goodhart, Catriona Hall, and Harriet O’Neill. References. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199689903.003.0020.

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This chapter presents key references on chest medicine, endocrinology, gastroenterology, renal medicine, haematology, infectious diseases, neurology, oncology and palliative care, rheumatology, surgery, clinical chemistry, radiology, practical procedures, and emergency medicine
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7

Watson, Max, Caroline Lucas, Andrew Hoy, and Jo Wells. The management of pain. Oxford University Press, 2010. http://dx.doi.org/10.1093/med/9780199234356.003.0012.

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This chapter covers physical pain in patients with cancer, assessment of pain, pain classification, principles of pain management, breakthrough pain, step 1 analgesics, step 2 analgesics, and step 3 analgesics. The chapter also covers opioid equivalence for transdermal patches, approximate equivalent doses for opioid analgesics for adults, neuropathic pain, anaesthetic procedures in palliative care, chemical neurolysis for cancer pain, and pain and difficulties in communication.
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8

Meyer, Mark J., and Norbert J. Weidner. Do-Not-Resuscitate Orders in the OR. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199764495.003.0006.

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A physician signs a do-not-resuscitate order (DNR) when aggressive resuscitation measures will not benefit the patient in the presence of a life-threatening illness. Many children living with a life-threatening illness derive benefit from invasive diagnostic and therapeutic procedures such as tracheostomies, peripherally inserted central lines, gastrostomy tubes, and tumor debulking procedures. These procedures are considered palliative rather than curative in that they improve or preserve quality of life but do not prevent progression of the underlying condition. In children, the presence of
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9

Sharma, Manohar, Karen H. Simpson, Michael I. Bennett, and Sanjeeva Gupta, eds. Practical Management of Complex Cancer Pain. 2nd ed. Oxford University Press, 2022. http://dx.doi.org/10.1093/med/9780198865667.001.0001.

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This new edition of the Practical Management of Complex Cancer Pain has been fully updated and expanded, with five new chapters on novel interventional techniques in cancer pain amelioration. The book provides advice on advanced pain management, emphasising the suitability and selection of patients for different invasive and complex procedures based on patient history. Case histories are included throughout the text to give the reader insight into the complexities of holistic management, with pain being only one component in the distress that cancer causes for both patients and families. The b
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10

Gottlieb, Erin A., and David F. Vener. Single-Ventricle Physiology. Edited by Erin S. Williams, Olutoyin A. Olutoye, Catherine P. Seipel, and Titilopemi A. O. Aina. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190678333.003.0026.

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Pediatric and adult patients with single ventricle physiology may present for elective and emergent procedures, and it is critical for pediatric anesthesiologists to be familiar with the stages of palliation. In addition, basic knowledge of how to manage each stage perioperatively is required to avoid morbidity and mortality. This chapter describes the anatomy and physiology of and ventilation and oxygenation strategies for each stage of single ventricle palliation. It also discusses the risks associated with anesthetizing the single-ventricle patient with a modified Blalock-Taussig shunt, the
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11

Wilkinson, Ian B., Tim Raine, Kate Wiles, Anna Goodhart, Catriona Hall, and Harriet O'Neill. Oxford Handbook of Clinical Medicine. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199689903.001.0001.

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The Oxford Handbook of Clinical Medicine provides a unique resource for medical students and junior doctors as a definitive guide to medicine. It is divided into 19 chapters, each covering a core area, including chest medicine, endocrinology, gastroenterology, renal medicine, haematology, infectious diseases, neurology, oncology and palliative care, rheumatology, surgery, clinical chemistry, radiology, practical procedures, and emergency medicine. It presents clinical information in a clear way that makes it easy to revise, remember, and implement on the ward. It gives reliable advice on what
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12

Mundy, Anthony R., and Daniela E. Andrich. Urethral strictures. Edited by Anthony R. Mundy. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0050.

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Urethral strictures are common and almost all urologists will deal with them on a regular if not daily basis. They have always been common and the history of the subject stretches back to 3,000 BC. Urethral dilators have been found in the tombs of the pharaohs so that they might be able to catheterize themselves or dilate their own strictures in the afterlife. Urethrotomy and dilatation are two of the most frequently performed procedures in urology. But these are usually only palliative, and curative treatment by urethroplasty is performed by very few urologists. In part this is because most s
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13

Cutter, David, and Martin Scott-Brown. Diagnosis and staging of cancer. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0324.

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The accurate diagnosis of the precise type and stage of a malignancy is a vital part of cancer management. Treatment options and decisions vary significantly between various stages of the same malignancy (e.g. treatment with radical vs palliative intent) and also between specific histological subtypes of a cancer arising from the same organ (e.g. small-cell lung cancer vs non-small-cell lung cancer). It is therefore of critical importance that as much accurate information about each individual case is obtained. This is achieved with a variety of diagnostic procedures which allow the multidisci
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14

Daniel, Rene, and Catriona M. Harrop, eds. Medical Management of Neurosurgical Patients. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780190913779.001.0001.

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Modern management of neurosurgical patients requires close cooperation between neurosurgeons and other specialists. The latter include internists, nurse practitioners, and physician assistants. This textbook aims to provide for these professionals a guide to the challenges associated with the medical management of these patients. It gives an overview of neurosurgical operations and procedures, seizure management, and preoperative risk stratification. It further discusses the intricacies of the management of fever, infection, electrolytes, bleeding disorders, and endocrine problems in the conte
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15

Swarm, Robert A., Menelaos Karanikolas, Lesley K. Rao, and Michael J. Cousins. Interventional approaches for chronic pain. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656097.003.0098.

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Severe, uncontrolled pain remains common in populations with serious or life-threatening illness. Despite the availability of oral opioid therapy in most developed countries, an estimated 10-30% of people with advanced cancer have inadequate pain control. Published guidelines endorse the view that these patients should be considered for procedural, or so-called interventional, pain therapies. Generally accepted indications for interventional pain therapies include (a) uncontrolled pain despite systemic analgesics and (b) unacceptable systemic analgesic adverse effects. This chapter describes t
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16

McKenzie, Ian. Single Ventricle Physiology. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199764495.003.0031.

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Congenital cardiac abnormalities in which there is functionally only a single ventricle are a heterogeneous group of conditions. These include patients with marked hypoplasia of one ventricle, usually with hypoplasia or atresia of the inflow of the ventricle, such as in hypoplastic left heart syndrome or conditions where surgical separation of the flow to each ventricle is not possible, such as double-inlet left ventricle. The most common pathway for palliating these conditions will be to use cavopulmonary connections to provide lung blood flow direct from systemic venous return (reliant on sy
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17

Kellum, John A. Rapid Response System. Edited by Raghavan Murugan and Joseph M. Darby. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190612474.001.0001.

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This handbook provides a practical approach to the evaluation, differential diagnosis, and management of common medical and surgical emergencies such as cardiac arrest, acute respiratory failure, seizures, and hemorrhagic shock occurring in hospitalized patients. Less common and special circumstances such as pediatric, obstetric, oncologic, neurologic, and behavioral emergencies as well as palliative care for terminally ill patients encountered in the context of rapid response team (RRT) events are also discussed. An overview of commonly performed bedside emergency procedures by rapid response
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