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Journal articles on the topic 'Palliative sedation'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Murillo-Zamora, Efrén, Nallely A. García-López, Ana de Santiago-Ruiz, Alcira Emperatriz Chávez-Lira, Oliver Mendoza-Cano, and José Guzmán-Esquivel. "Characterisation of palliative sedation use in inpatients at a medium-stay palliative care unit." International Journal of Palliative Nursing 26, no. 7 (2020): 341–45. http://dx.doi.org/10.12968/ijpn.2020.26.7.341.

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Background Palliative sedation has been used to refer to the practice of providing symptom control through the administration of sedative drugs. The objective of this article was to characterise palliative sedation use in inpatients at a medium-stay palliative care unit. Material and methods A cross-sectional study was conducted on 125 randomly selected patients (aged 15 or older) who had died in 2014. The Palliative Performance Scale was used to evaluate the functional status. Results Palliative sedation was documented in 34.4% of the patients and midazolam was the most commonly used sedative

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2

Twycross, Robert. "Reflections on palliative sedation." Palliative Care: Research and Treatment 12 (January 2019): 117822421882351. http://dx.doi.org/10.1177/1178224218823511.

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‘Palliation sedation’ is a widely used term to describe the intentional administration of sedatives to reduce a dying person’s consciousness to relieve intolerable suffering from refractory symptoms. Research studies generally focus on either ‘continuous sedation until death’ or ‘continuous deep sedation’. It is not always clear whether instances of secondary sedation (i.e. caused by specific symptom management) have been excluded. Continuous deep sedation is controversial because it ends a person’s ‘biographical life’ (the ability to interact meaningfully with other people) and shortens ‘biol

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3

Lynch, Maureen. "Palliative Sedation." Clinical Journal of Oncology Nursing 7, no. 6 (2003): 653–57. http://dx.doi.org/10.1188/03.cjon.653-657.

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4

Lawson, Mary. "Palliative Sedation." Clinical Journal of Oncology Nursing 15, no. 6 (2011): 589–90. http://dx.doi.org/10.1188/11.cjon.589-590.

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5

Vayne-Bossert, Petra, and Gilbert B. Zulian. "Palliative Sedation." American Journal of Hospice and Palliative Medicine® 30, no. 8 (2013): 786–90. http://dx.doi.org/10.1177/1049909112472930.

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6

Gurschick, Lauren, Deborah K. Mayer, and Laura C. Hanson. "Palliative Sedation." American Journal of Hospice and Palliative Medicine® 32, no. 6 (2014): 660–71. http://dx.doi.org/10.1177/1049909114533002.

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7

Eisenchlas, Jorge H. "Palliative sedation." Current Opinion in Supportive and Palliative Care 1, no. 3 (2007): 207–12. http://dx.doi.org/10.1097/spc.0b013e3282f19f87.

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8

Manzini, Jorge L. "Palliative sedation." Current Opinion in Supportive and Palliative Care 5, no. 3 (2011): 279–84. http://dx.doi.org/10.1097/spc.0b013e3283492acd.

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9

Gallagher, R., and C. Baldwin. "Palliative sedation." Canadian Medical Association Journal 186, no. 3 (2014): 212. http://dx.doi.org/10.1503/cmaj.114-0010.

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10

Cargill, D. "Palliative sedation." Canadian Medical Association Journal 186, no. 3 (2014): 212. http://dx.doi.org/10.1503/cmaj.114-0011.

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11

Rousseau, Paul C. "Palliative sedation." American Journal of Hospice and Palliative Medicine® 19, no. 5 (2002): 295–97. http://dx.doi.org/10.1177/104990910201900501.

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12

Brender, Erin. "Palliative Sedation." JAMA 294, no. 14 (2005): 1850. http://dx.doi.org/10.1001/jama.294.14.1850.

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13

Nelson Bander, Peg. "Palliative Sedation." Journal of Hospice & Palliative Nursing 19, no. 5 (2017): 394–401. http://dx.doi.org/10.1097/njh.0000000000000368.

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14

Cohen-Almagor, Raphael, and E. Wesley Ely. "Euthanasia and palliative sedation in Belgium." BMJ Supportive & Palliative Care 8, no. 3 (2018): 307–13. http://dx.doi.org/10.1136/bmjspcare-2017-001398.

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The aim of this article is to use data from Belgium to analyse distinctions between palliative sedation and euthanasia. There is a need to reduce confusion and improve communication related to patient management at the end of life specifically regarding the rapidly expanding area of patient care that incorporates a spectrum of nuanced yet overlapping terms such as palliative care, sedation, palliative sedation, continued sedation, continued sedation until death, terminal sedation, voluntary euthanasia and involuntary euthanasia. Some physicians and nurses mistakenly think that relieving suffer

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15

Rampello, G., R. Grisetti, P. Leonardi, et al. "Palliative care and palliative sedation." Annals of Oncology 26 (October 2015): vi119. http://dx.doi.org/10.1093/annonc/mdv346.23.

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16

Maltoni, Marco, Emanuela Scarpi, Marta Rosati, et al. "Palliative Sedation in End-of-Life Care and Survival: A Systematic Review." Journal of Clinical Oncology 30, no. 12 (2012): 1378–83. http://dx.doi.org/10.1200/jco.2011.37.3795.

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Purpose Palliative sedation is a clinical procedure aimed at relieving refractory symptoms in patients with advanced cancer. It has been suggested that sedative drugs may shorten life, but few studies exist comparing the survival of sedated and nonsedated patients. We present a systematic review of literature on the clinical practice of palliative sedation to assess the effect, if any, on survival. Methods A systematic review of literature published between January 1980 and December 2010 was performed using MEDLINE and EMBASE databases. Search terms included palliative sedation, terminal sedat

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17

Gielen, Joris, Stef Van den Branden, Trudie Van Iersel, and Bert Broeckaert. "Flemish palliative-care nurses’ attitudes to palliative sedation." Nursing Ethics 19, no. 5 (2012): 692–704. http://dx.doi.org/10.1177/0969733011436026.

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Palliative sedation is an option of last resort to control refractory suffering. In order to better understand palliative-care nurses’ attitudes to palliative sedation, an anonymous questionnaire was sent to all nurses (589) employed in palliative care in Flanders (Belgium). In all, 70.5% of the nurses ( n = 415) responded. A large majority did not agree that euthanasia is preferable to palliative sedation, were against non-voluntary euthanasia in the case of a deeply and continuously sedated patient and considered it generally better not to administer artificial floods or fluids to such a pat

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18

Twycross, Robert. "Regarding Palliative Sedation." Journal of Pain and Symptom Management 53, no. 6 (2017): e13-e15. http://dx.doi.org/10.1016/j.jpainsymman.2017.01.002.

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19

Hulme, Bill, and Colin Campbell. "Palliative sedation therapy." British Journal of Hospital Medicine 70, no. 4 (2009): 208–11. http://dx.doi.org/10.12968/hmed.2009.70.4.41623.

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20

Morrison, Katherine, and Jeanie Youngwerth. "Palliative Sedation Therapy." Hospital Medicine Clinics 5, no. 1 (2016): 101–13. http://dx.doi.org/10.1016/j.ehmc.2015.08.010.

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21

Vivat, Bella, Lucy Bemand-Qureshi, Jane Harrington, Sarah Davis, and Patrick Stone. "Palliative care specialists in hospice and hospital/community teams predominantly use low doses of sedative medication at the end of life for patient comfort rather than sedation: Findings from focus groups and patient records for I-CAN-CARE." Palliative Medicine 33, no. 6 (2019): 578–88. http://dx.doi.org/10.1177/0269216319826007.

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Background: Little research has explored the detail of practice when using sedative medications at the end of life. One work package of the I-CAN-CARE research programme investigates this in UK palliative care. Aims: To investigate current practices when using sedative medication at the end of life in London, UK, by (1) qualitatively exploring the understandings of palliative care clinicians, (2) examining documented sedative use in patient records and (3) comparing findings from both investigations. Design: We conducted focus groups with experienced palliative care physicians and nurses, and

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22

De Vries, Kay, and Marek Plaskota. "Ethical dilemmas faced by hospice nurses when administering palliative sedation to patients with terminal cancer." Palliative and Supportive Care 15, no. 2 (2016): 148–57. http://dx.doi.org/10.1017/s1478951516000419.

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AbstractObjective:Palliative sedation is a method of symptom management frequently used in hospices to treat uncontrolled symptoms at the end of life. There is a substantial body of literature on this subject; however, there has been little research into the experiences of hospice nurses when administering palliative sedation in an attempt to manage the terminal restlessness experienced by cancer patients.Method:Semistructured interviews were conducted with a purposive sample of seven hospice nurses who had cared for at least one patient who had undergone palliative sedation within the past ye

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23

Lux, Michael R., Bridget McCrate Protus, Jason Kimbrel, and Phyllis Grauer. "A Survey of Hospice and Palliative Care Physicians Regarding Palliative Sedation Practices." American Journal of Hospice and Palliative Medicine® 34, no. 3 (2016): 217–22. http://dx.doi.org/10.1177/1049909115615128.

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Context: Patients nearing the end of life may experience symptoms that are refractory to standard therapeutic options. Physicians may consider palliative sedation to relieve intolerable suffering. There is limited clinical literature regarding preferred medications for palliative sedation. Objectives: To determine the preferred medications physicians use when implementing palliative sedation. Methods: An Internet-based, cross-sectional survey of hospice and palliative care physicians in the United States. Results: A link to the survey was e-mailed to 3130 physician members of the American Acad

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24

Six, Stefaan, Steven Laureys, Jan Poelaert, et al. "Should we include monitors to improve assessment of awareness and pain in unconscious palliatively sedated patients? A case report." Palliative Medicine 33, no. 6 (2019): 712–16. http://dx.doi.org/10.1177/0269216319835149.

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Background: Awareness and pain during palliative sedation is typically assessed by observational scales, but the use of such scales has been put into question. Case presentation: A woman in her mid-80s was admitted to a palliative care unit, presenting with chronic lymphatic leukemia, depression, and a cerebrovascular accident, with right-sided hemiplegia and aphasia. The patient was unable to eat and was suffering from nausea and vomiting. Before admission, the patient had expressed her desire to discontinue treatment on several occasions. Case management: The decision was made to initiate pa

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25

Barathi, B. "Palliative sedation at home." Indian Journal of Palliative Care 18, no. 1 (2012): 74. http://dx.doi.org/10.4103/0973-1075.97477.

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26

Meyer, Mark, and Robert Macauley. "Pediatric Palliative Sedation (FR414)." Journal of Pain and Symptom Management 45, no. 2 (2013): 372. http://dx.doi.org/10.1016/j.jpainsymman.2012.10.095.

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27

Davis, Mellar S. "Palliative sedation: four questions." Progress in Palliative Care 17, no. 4 (2009): 203–4. http://dx.doi.org/10.1179/096992609x12455871936946.

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28

&NA;. "Palliative Sedation and Nursing." Journal of Hospice & Palliative Nursing 9, no. 2 (2007): 107–8. http://dx.doi.org/10.1097/01.njh.0000263304.33816.cf.

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29

Claessens, Patricia, Ellen Genbrugge, Rita Vannuffelen, Bert Broeckaert, Paul Schotsmans, and Johan Menten. "Palliative Sedation and Nursing." Journal of Hospice & Palliative Nursing 9, no. 2 (2007): 100–106. http://dx.doi.org/10.1097/01.njh.0000263527.14800.2b.

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30

Payne, Sheila A., and Jeroen Hasselaar. "European Palliative Sedation Project." Journal of Palliative Medicine 23, no. 2 (2020): 154–55. http://dx.doi.org/10.1089/jpm.2019.0606.

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31

Rosengarten, Ora S., Yonat Lamed, Timna Zisling, Ayelet Feigin, and Jeremy M. Jacobs. "Palliative Sedation at Home." Journal of Palliative Care 25, no. 1 (2009): 5–11. http://dx.doi.org/10.1177/082585970902500102.

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A large number of dying patients receive palliative care at home, and although palliative sedation (PS) may be indicated, literature describing PS at home is scarce. This study is a retrospective description of PS delivered to terminal patients at home from December 2000 to March 2006. A total of 36 patients (with a median age of 65) received home PS. Cancer was the diagnosis for 35 patients, and most patients suffered more than one symptom — most commonly, intractable pain, followed by agitation and existential suffering. Drugs used included midazolam, morphine, haloperidol, fentanyl TTS, and

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32

Sulistio, Merlina, Robert Wojnar, and Natasha G. Michael. "Propofol for palliative sedation." BMJ Supportive & Palliative Care 10, no. 1 (2019): 4–6. http://dx.doi.org/10.1136/bmjspcare-2019-001899.

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Palliative sedation is the intentional use of sedatives to manage refractory symptom(s), such as pain and/or terminal restlessness. This case report describes the successful use of propofol, an ultra-fast-acting anaesthetic agent commonly used for anaesthesia induction and maintenance to manage refractory agitated delirium in an acute inpatient palliative medicine setting.

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33

Beel, Alexandra C., Pamela G. Hawranik, Susan E. McClement, and Paul J. Daeninck. "Palliative sedation: Nurses’ perceptions." International Journal of Palliative Nursing 12, no. 11 (2006): 510–18. http://dx.doi.org/10.12968/ijpn.2006.12.11.22398.

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34

Vissers, Kris CP, Jeroen Hasselaar, and Stans AHHVM Verhagen. "Sedation in palliative care." Current Opinion in Anaesthesiology 20, no. 2 (2007): 137–42. http://dx.doi.org/10.1097/aco.0b013e328049557b.

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35

Chambaere, Kenneth, Joachim Cohen, Sigrid Sterckx, Freddy Mortier, Judith A. C. Rietjens, and Luc Deliens. "Palliative Sedation in Flemish Palliative Care Units." Journal of Pain and Symptom Management 41, no. 6 (2011): e1-e2. http://dx.doi.org/10.1016/j.jpainsymman.2011.03.005.

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36

Henderson, Carrie M., Michael FitzGerald, K. Sarah Hoehn, and Norbert Weidner. "Pediatrician Ambiguity in Understanding Palliative Sedation at the End of Life." American Journal of Hospice and Palliative Medicine® 34, no. 1 (2016): 5–19. http://dx.doi.org/10.1177/1049909115609294.

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Context: Palliative sedation is a means of relieving intractable symptoms at the end of life, however, guidelines about its use lack consistency. In addition, ethical concerns persist around the practice. There are reports of palliative sedation in the pediatric literature, which highlight various institutional perspectives. Objectives: This survey of 4786 pediatric providers sought to describe their knowledge of and current practices around pediatric palliative sedation. Methods: Our survey was administered to pediatricians who care for children at the end of life. The survey assessed agreeme

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37

Riisfeldt, Thomas D. "A response to critics: weakening the ethical distinction between euthanasia, palliative opioid use and palliative sedation." Journal of Medical Ethics 46, no. 1 (2019): 59–62. http://dx.doi.org/10.1136/medethics-2019-105906.

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My essay ‘Weakening the ethical distinction between euthanasia, palliative opioid use and palliative sedation’ has recently generated some critique which I will attempt to address in this response. Regarding the empirical question of whether palliative opioid and sedative use shorten survival time, Schofield et al raise the three concerns that my literature review contains a cherry-picking bias through focusing solely on the palliative care population, that continuous deep palliative sedation falls beyond the scope of routine palliative care, and that my research may contribute to opiophobia a

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38

van Wijlick, Eric, Marian Verkerk, Alexander de Graeff, and Johan Legemaate. "Palliative Sedation in The Netherlands: Starting-points and Contents of a National Guideline." European Journal of Health Law 14, no. 1 (2007): 61–73. http://dx.doi.org/10.1163/092902707x185451.

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AbstractIn December 2005 the first national guideline for palliative sedation in the Netherlands was published. This guideline was developed by a committee of the Royal Dutch Medical Association, at the request of the Dutch government. The guideline defines palliative sedation as 'the intentional lowering of consciousness of a patient in the last phase of his or her life'. According to the guideline the objective of palliative sedation is to relieve suffering, and lowering consciousness is a means to achieve this. It is very important that palliative sedation is given for the right indication,

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39

Arevalo, Jimmy J., Tijn Brinkkemper, Agnes van der Heide, et al. "Palliative Sedation: Reliability and Validity of Sedation Scales." Journal of Pain and Symptom Management 44, no. 5 (2012): 704–14. http://dx.doi.org/10.1016/j.jpainsymman.2011.11.010.

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40

Giebel, Heidi. "Ethical end-of-life palliative care: response to Riisfeldt." Journal of Medical Ethics 46, no. 1 (2019): 51–52. http://dx.doi.org/10.1136/medethics-2019-105451.

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In a recent article, 1 Riisfeldt attempts to show that the principle of double effect (PDE) is unsound as an ethical principle and problematic in its application to palliative opioid and sedative use in end-of-life care. Specifically, he claims that (1) routine, non-lethal opioid and sedative administration may be “intrinsically bad” by PDE’s standards, (2) continuous deep palliative sedation (or “terminal sedation”) should be treated as a bad effect akin to death for purposes of PDE, (3) PDE cannot coherently be applied in cases where death “indirectly” furthers an agent’s intended end of pai

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41

Brinkkemper, Tijn, Arjanne M. van Norel, Karolina M. Szadek, Stephan A. Loer, Wouter WA Zuurmond, and Roberto SGM Perez. "The use of observational scales to monitor symptom control and depth of sedation in patients requiring palliative sedation: A systematic review." Palliative Medicine 27, no. 1 (2011): 54–67. http://dx.doi.org/10.1177/0269216311425421.

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Background: Palliative sedation is the intentional lowering of consciousness of a patient in the last phase of life to relieve suffering from refractory symptoms such as pain, delirium and dyspnoea. Aim: In this systematic review, we evaluated the use of monitoring scales to assess the degree of control of refractory symptoms and/or the depth of the sedation. Design: A database search of PubMed and Embase was performed up to January 2010 using the search terms ‘palliative sedation’ OR ‘terminal sedation’. Data sources: Retro- and prospective studies as well as reviews and guidelines containing

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42

Alshammary, SamiAyed, Juri Salamah, and Stuart Brown. "Palliative sedation and ethical dilemma." Journal of Health Specialties 6, no. 2 (2018): 87. http://dx.doi.org/10.4103/jhs.jhs_21_18.

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43

Belgrave, Kevin, and Pablo Requena. "A Primer on Palliative Sedation." National Catholic Bioethics Quarterly 12, no. 2 (2012): 263–81. http://dx.doi.org/10.5840/ncbq201212253.

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44

Mervyn Koh, Yong Hwang, Onn Kei Angel Lee, and Huei Yaw Wu. "“Palliative” and Not “Terminal” Sedation." Journal of Pain and Symptom Management 37, no. 4 (2009): e5-e7. http://dx.doi.org/10.1016/j.jpainsymman.2008.11.005.

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45

Rousseau, Paul. "Palliative Sedation: The Author's Response." Journal of Palliative Medicine 8, no. 4 (2005): 702–3. http://dx.doi.org/10.1089/jpm.2005.8.702.

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46

Bruera, Eduardo. "Palliative Sedation: When and How?" Journal of Clinical Oncology 30, no. 12 (2012): 1258–59. http://dx.doi.org/10.1200/jco.2011.41.1223.

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47

WACHTER, KERRI. "Palliative Sedation: Proceed With Care." Internal Medicine News 41, no. 5 (2008): 1–8. http://dx.doi.org/10.1016/s1097-8690(08)70228-2.

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48

Rousseau, Paul. "Existential Distress and Palliative Sedation." Anesthesia & Analgesia 101, no. 2 (2005): 611–12. http://dx.doi.org/10.1213/01.ane.0000159014.71321.a2.

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49

Maltoni, Marco, Emanuela Scarpi, and Oriana Nanni. "Palliative sedation for intolerable suffering." Current Opinion in Oncology 26, no. 4 (2014): 389–94. http://dx.doi.org/10.1097/cco.0000000000000097.

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50

Hasselaar, Jeroen, Stans Verhagen, Rob Reuzel, Evert van Leeuwen, and Kris Vissers. "Palliative sedation is not controversial." Lancet Oncology 10, no. 8 (2009): 747–48. http://dx.doi.org/10.1016/s1470-2045(09)70210-4.

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