Academic literature on the topic 'Panaxytriol'

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Journal articles on the topic "Panaxytriol"

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Satoh, Mitsuru, Masayoshi Ishii, Mitsuo Watanabe, Kimiaki Isobe, Taketo Uchiyama, and Yasuo Fujimoto. "Absolute Structure of Panaxytriol." CHEMICAL & PHARMACEUTICAL BULLETIN 50, no. 1 (2002): 126–28. http://dx.doi.org/10.1248/cpb.50.126.

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Prasad, Kavirayani R., and Bandita Swain. "Total synthesis of panaxytriol and panaxydiol." Tetrahedron: Asymmetry 22, no. 12 (2011): 1261–65. http://dx.doi.org/10.1016/j.tetasy.2011.07.007.

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SATOH, Mitsuru, Naoki TAKEUCHI, and Yasuo FUJIMOTO. "Synthesis and Absolute Configuration of Panaxytriol." CHEMICAL & PHARMACEUTICAL BULLETIN 45, no. 7 (1997): 1114–16. http://dx.doi.org/10.1248/cpb.45.1114.

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Satoh, Mitsuru, Masayoshi Ishii, Mitsuo Watanabe, Kimiaki Isobe, Taketo Uchiyama, and Yasuo Fujimoto. "ChemInform Abstract: Absolute Structure of Panaxytriol." ChemInform 33, no. 29 (2010): no. http://dx.doi.org/10.1002/chin.200229224.

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Wang, Bang-Yan, Chen-Hao Zhu, Xue-Qiong Yang та ін. "Inducing Intermediates in Biotransformation of Natural Polyacetylene and A Novel Spiro-γ-Lactone from Red Ginseng by Solid Co-Culture of Two Gut Chaetomium globosum and The Potential Bioactivity Modification by Oxidative Metabolism". Molecules 25, № 5 (2020): 1216. http://dx.doi.org/10.3390/molecules25051216.

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The ω-hydroxyl-panaxytriol (1) and ω-hydroxyl-dihydropanaxytriol (2)—are rare examples of polyacetylene metabolism by microbial transformation, and these new metabolites (1, 2) from fermented red ginseng (FRG) by solid co-culture induction of two Chaetomium globosum should be the intermediates of biotransformation of panaxylactone (metabolite A). The metabolic pathway of panaxylactone was also exhibited. The ingredients of red ginseng (RG) also induced the production of rare 6/5/5 tricyclic ring spiro-γ-lactone skeleton (3). The ω-hydroxylation of new intermediates (1, 2) decreases cytotoxicit
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SATOH, M., N. TAKEUCHI, and Y. FUJIMOTO. "ChemInform Abstract: Synthesis and Absolute Configuration of Panaxytriol." ChemInform 28, no. 51 (2010): no. http://dx.doi.org/10.1002/chin.199751278.

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Hiramatsu, Genki, Kosuke Matsuda, Daisuke Uta, Kenichi Mihara, Ysuhunobu Andoh, and Toshiaki Kume. "Inhibitory effect of panaxytriol on thelipopolysaccharide-induced microglial activation." Proceedings for Annual Meeting of The Japanese Pharmacological Society 94 (2021): 2—Y—F1–1. http://dx.doi.org/10.1254/jpssuppl.94.0_2-y-f1-1.

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Hiramatsu, Genki, Daisuke Uta, Kenichi Mihara, Tsugunobu Andoh, and Toshiaki Kume. "Inhibitory effect of panaxytriol on BV-2 microglial cell activation." Journal of Pharmacological Sciences 145, no. 3 (2021): 273–78. http://dx.doi.org/10.1016/j.jphs.2021.01.001.

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Yun, Heedong, and Samuel J. Danishefsky. "Straightforward Synthesis of Panaxytriol: An Active Component of Red Ginseng." Journal of Organic Chemistry 68, no. 11 (2003): 4519–22. http://dx.doi.org/10.1021/jo0341665.

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Mao, Jianyou, Jiangchun Zhong, Bo Wang, et al. "Synthesis of panaxytriol and its stereoisomers as potential antitumor drugs." Tetrahedron: Asymmetry 27, no. 7-8 (2016): 330–37. http://dx.doi.org/10.1016/j.tetasy.2016.03.005.

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Dissertations / Theses on the topic "Panaxytriol"

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Wu, Jui-Hung, and 吳瑞鴻. "Synthetic Study of Antitumor Panaxytriol in Panax ginseng." Thesis, 2001. http://ndltd.ncl.edu.tw/handle/39522448093305059648.

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碩士<br>中國文化大學<br>應用化學研究所<br>89<br>Panax ginseng has been considered as one of the most important and valuable medicinal plants in traditional oriental medicine. It was reported to have numerous biological activity, including effects on the cardiovascular, immune, and nervous systems, and activity as an antidote, antitumor agent, or antitumor adjuvant and as an antidiabetic. Although ginseng has been used for thousands of years, its chemical constituents were gradually isolated until 1960s. In the last two decades, many unusual polyacetylene compounds were isolated from this traditional medic
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Hartung, John. "I. Radical Cyclizations Mediated by Transition Metal Hydrides II. Study toward the Total Synthesis of Pluraflavin A III. Cytoprotective Polyacetylenes Inspired by Panaxytriol." Thesis, 2012. https://doi.org/10.7916/D841744Q.

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The first part of the thesis describes radical cyclizations mediated by transition metal hydrides. CpCr(CO)3H and (H2O)2Co(dmgBF2)2 under H2 gas catalyzed the radical cyclization of 1,6-dienes to form 5- and 6-membered rings and the cyclization of a 1,6,11 triene to form a substituted decalin. Vanadium hydrides of the general formula HV(CO)4(P-P), where P-P is a chelating bisphosphine, were used to initiate radical cyclizations, but could only be used stoichiometrically. The method was expanded to include the synthesis of tetrahydrofurans by employing vinyl ethers as substrates. The second par
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Cho, Eun Jin. "I. Pt, Au, and Ru-catalyzed Reactions of multi-ynes: reactivity and selectivity : II. Synthetic studies on natural products: (3R,9R,10R)-panaxytriol and (-)-dactylolide /." 2008. http://www.library.wisc.edu/databases/connect/dissertations.html.

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Swain, Bandita. "Total Synthesis Of Bio-active Oxylipins And Diyne Containing Natural Products." Thesis, 2011. https://etd.iisc.ac.in/handle/2005/2347.

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Total synthesis of natural products is of contemporary interest in organic synthesis. One of the useful ways to synthesize the natural products is to originate from inexpensive chiral pool compounds abundantly available in nature. In this context, our research group is actively involved in the use of tartaric acid as the four carbon four hydroxy building block in the synthesis of a number of natural products of therapeutic importance. Our strategy relies on the utility of γ-hydroxy amides derived from tartaric acid involving a controlled addition of Grignard reagents and stereoselective reduct
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Swain, Bandita. "Total Synthesis Of Bio-active Oxylipins And Diyne Containing Natural Products." Thesis, 2011. http://etd.iisc.ernet.in/handle/2005/2347.

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Total synthesis of natural products is of contemporary interest in organic synthesis. One of the useful ways to synthesize the natural products is to originate from inexpensive chiral pool compounds abundantly available in nature. In this context, our research group is actively involved in the use of tartaric acid as the four carbon four hydroxy building block in the synthesis of a number of natural products of therapeutic importance. Our strategy relies on the utility of γ-hydroxy amides derived from tartaric acid involving a controlled addition of Grignard reagents and stereoselective reduct
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Books on the topic "Panaxytriol"

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I. Radical Cyclizations Mediated by Transition Metal Hydrides II. Study toward the Total Synthesis of Pluraflavin A III. Cytoprotective Polyacetylenes Inspired by Panaxytriol. [publisher not identified], 2012.

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Book chapters on the topic "Panaxytriol"

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Taber, Douglass. "Alkene Metathesis: Synthesis of Panaxytriol (Lee), Isofagomine (Imahori and Takahata), Elatol (Stoltz), 5-F2t -Isoprostane (Snapper), and Ottelione B (Clive)." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0030.

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Alkene metathesis has been used to prepare more and more challenging natural products. The first and second generation Grubbs catalysts 1 and 2 and the Hoveyda catalyst 3 are the most widely used. Daesung Lee of the University of Illinois at Chicago designed (Organic Lett. 2008, 10, 257) a clever chain-walking cross metathesis, combining 4 and 5 to make 6. The diyne 3 was carried on (3R, 9R, 10R )-Panaxytriol 7. Tatsushi Imahori and Hiroki Takahata of Tohoku Pharmaceutical University found (Tetrahedron Lett. 2008, 49, 265) that of the several derivatives investigated, the unprotected alcohol 8 cyclized most efficiently. Selective cleavage of the monosubstituted alkene followed by hydroboration delivered the alkaloid Isofagomine 10. Brian M. Stoltz of Caltech established (J. Am. Chem. Soc. 2008 , 130 , 810) the absolute configuration of the halogenated chamigrene Elatol 14 using the enantioselective enolate allylation that he had previously devised. A key feature of this synthesis was the stereocontrolled preparation of the cis bromohydrin. Marc L. Snapper of Boston College opened (J. Org. Chem. 2008, 73, 3754) the strained cyclobutene 15 with ethylene to give the diene 16. Remarkably, cross metathesis with 17 delivered 18 with high regioselectivity, setting the stage for the preparation of the 5-F2t - Isoprostane 19. Derrick L. J. Clive of the University of Alberta assembled (J. Org. Chem. 2008, 73, 3078) Ottelione B 26 from the enantiomerically-pure aldehyde 20. Conjugate addition of the Grignard reagent 21 derived from chloroprene gave the kinetic product 22, that was equilibrated to the more stable 23. Addition of vinyl Grignard followed by selective ring-closing metathesis then led to 26.
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Conference papers on the topic "Panaxytriol"

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Chou, Ting-Chao, Huajin Dong, Xiuguo Zhang, Xiaoguang Lei, and Samuel J. Danishefsky. "Abstract 3521: Alleviation of cancer chemotherapeutic agent-induced toxicity by the synthetic panaxytriol analogues of Panax Ginseng." In Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL. American Association for Cancer Research, 2011. http://dx.doi.org/10.1158/1538-7445.am2011-3521.

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