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Journal articles on the topic 'Pancreatic cysts'

Author: Grafiati

Published: 28 May 2022

Last updated: 31 July 2025

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1

Daniel, Phillip, Siddharth Shukla, Nidhi Prabhakar, et al. "Infected Pancreatic Hydatid Cyst with Cysto-Pancreatic Fistula Presenting as Acute Pancreatitis." Journal of Digestive Endoscopy 10, no. 04 (2019): 234–36. http://dx.doi.org/10.1055/s-0040-1708069.

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AbstractHydatid cysts can be found in almost any organ of the body with the most common sites being liver, lung, spleen, and kidney. A pancreatic hydatid cyst is rare but an isolated pancreatic hydatid cyst is even rarer. Cysts in the head of pancreas usually present with jaundice, whereas cysts located in the body and tail are usually asymptomatic. We present a rare case of isolated pancreatic hydatid cyst that presented with acute pancreatitis and mimicked a pancreatic fluid collection.

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Abdellah, Tarek, Sayed Shalaby, Amira Salem та ін. "Pancreatic cyst fluid interleukin-1 beta (IL-1β) level in predicting the risk of malignancy in pancreatic cysts". Egyptian journal of Immunology 29, № 4 (2022): 75–83. http://dx.doi.org/10.55133/eji.290407.

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Pancreatic cystic lesions (PCLs) may be accidentally discovered in up to 13.5% of cases. These PCLs are of multiple types, including mucinous cysts (intra-ductal papillary mucinous neoplasms [IPMN] and mucinous cystic neoplasms [MCN]) that have a risk of malignant transformation. The difficulty in differentiation between the various PCLs and their unpredictable risk of malignant transformation makes their management difficult. The new diagnostic tools of PCLs often include endoscopic ultrasound guided fine needle aspiration (EUS-FNA) for pancreatic cyst fluid analysis. This study aimed to dete

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Deicy, Susana Rendón Vargas, Román Vargas Manuel, Quetzalcóatl Vega Morales Alexis, Laura Esmeralda Muñoz Avendaño Ana, and Eduardo Vázquez Flores Carlos. "Distal Pancreatectomy with Splenectomy in Pancreatic Tail Cyst: Case Report." International Journal Of Medical Science And Clinical Research Studies 03, no. 06 (2023): 1176–78. https://doi.org/10.5281/zenodo.8082383.

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Pancreatic cyst is a pathological condition characterized by the presence of a fluid-filled cavity or sac within the pancreatic tissue. It can arise from various etiologies, including chronic pancreatitis, acute pancreatitis, pancreatic duct obstruction, and benign or malignant pancreatic lesions.   Histopathological classification of pancreatic cysts reveals distinct subtypes such as pseudopapillary cysts, serous cysts, mucinous cysts, solid cysts, and intraductal papillary mucinous neoplasms, each exhibiting unique characteristics that influence clinical management. Diagnosis of pancrea

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4

Meagher, Timothy, and Andreas Armuss. "Pancreatic Cysts." Journal of Insurance Medicine 46, no. 2 (2016): 60–65. http://dx.doi.org/10.17849/0743-6661-46.2.60.

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Pancreatic cysts are more common than before, largely because of widespread abdominal imaging. Pancreatic cystic neoplasms (PCN) are relevant to risk selection on 2 counts: they constitute more than 50% of all pancreatic cysts and, in contrast to the other 2 cyst types, are capable of malignant transformation. The majority of PCNs are benign at time of diagnosis and will follow a benign course. The challenge is to identify those PCNs that are malignant or will undergo malignant transformation with time. The purpose of this article is to provide pointers that can help meet this challenge while

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Javia, Siddharth, Satish Munigala, Sushovan Guha, and Banke Agarwal. "EUS Morphology Is Reliable in Selecting Patients with Mucinous Pancreatic Cyst(s) Most Likely to Benefit from Surgical Resection." Gastroenterology Research and Practice 2017 (2017): 1–8. http://dx.doi.org/10.1155/2017/9863952.

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Background and Study Aims. Endoscopic ultrasound (EUS) surveillance of patients with mucinous pancreatic cysts relies on the assessment of morphologic features suggestive of malignant transformation. These criteria were derived from the evaluation of surgical pathology in patients with pancreatic cysts who underwent surgery. Reliability of these criteria when evaluated by EUS in identifying lesions which require surgery has still not been established. Patients and Methods. This retrospective cohort study included seventy-eight patients who underwent surgical resection of pancreatic cysts based

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Jhala, Nirag, Piyachat Srimunta, and Darshana Jhala. "Role of Ancillary Testing on Endoscopic US-Guided Fine Needle Aspiration Samples from Cystic Pancreatic Neoplasms." Acta Cytologica 64, no. 1-2 (2019): 124–35. http://dx.doi.org/10.1159/000502372.

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Pancreatic cysts are increasingly detected on imaging studies. Accurate determination of the cyst type is important to provide appropriate care for the patients. It is also very clear that not one single modality can provide adequate diagnostic information. A multidisciplinary approach is the key to the diagnosis of pancreatic cysts. In this setting, the role of ancillary testing, which includes biochemical testing (carcinoembryonic antigen and amylase levels in the cyst), molecular testing (e.g., KRAS, GNAS, VHL, and CTNB1), and/or immunohistochemical tests are very important to obtain an acc

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Kromrey, Marie-Luise, Robin Bülow, Jenny Hübner, et al. "Prospective study on the incidence, prevalence and 5-year pancreatic-related mortality of pancreatic cysts in a population-based study." Gut 67, no. 1 (2017): 138–45. http://dx.doi.org/10.1136/gutjnl-2016-313127.

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ObjectiveTo analyse the prevalence, incidence and clinical relevance of pancreatic cysts detected as incidental finding in a population-based longitudinal study.DesignA total of 1077 participants (521 men, mean age 55.8±12.8 years) of 2333 participants from the population-based Study of Health in Pomerania (SHIP) underwent magnetic resonance cholangiopancreaticography (MRCP) at baseline (2008–2012). MRCP was analysed for pancreatic cysts with a diameter ≥2 mm. 676/1077 subjects received a 5-year follow-up (2014–2016). The prevalence and incidence of pancreatic cysts (weighted for study partici

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Abdelkader, Amrou, Bryan Hunt, Christopher P. Hartley, Nicole C. Panarelli, and Tamara Giorgadze. "Cystic Lesions of the Pancreas: Differential Diagnosis and Cytologic-Histologic Correlation." Archives of Pathology & Laboratory Medicine 144, no. 1 (2019): 47–61. http://dx.doi.org/10.5858/arpa.2019-0308-ra.

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Context.— Pancreatic cystic lesions (PCLs) are very common, and their detection is increasing with the advances in imaging techniques. Because of the major implications for management, distinguishing between neoplastic and nonneoplastic PCLs is critical. Neoplastic cysts with potential to progress into cancer include mucinous PCLs (intraductal papillary mucinous neoplasms and mucinous cystic neoplasms) and nonmucinous cysts (solid pseudopapillary tumors, serous cystic neoplasms, and neuroendocrine tumors with cystic degeneration). Nonneoplastic cysts with no risk of malignant transformation in

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Vargas, Alejandra, Priyata Dutta, Eileen S. Carpenter, and Jorge D. Machicado. "Endoscopic Ultrasound-Guided Ablation of Premalignant Pancreatic Cysts and Pancreatic Cancer." Diagnostics 14, no. 5 (2024): 564. http://dx.doi.org/10.3390/diagnostics14050564.

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Pancreatic cancer is on the rise and expected to become the second leading cause of cancer-related death by 2030. Up to a one-fifth of pancreatic cancers may arise from mucinous pancreatic cysts, which are frequently present in the general population. Currently, surgical resection is the only curative approach for pancreatic cancer and its cystic precursors. However, only a dismal proportion of patients are eligible for surgery. Therefore, novel treatment approaches to treat pancreatic cancer and precancerous pancreatic cysts are needed. Endoscopic ultrasound (EUS)-guided ablation is an emergi

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10

Poola, Shiva, Shachar Laks, Peter Kragel, and Kara Regan. "Intrapancreatic Accessory Spleen Masquerading as a Pancreatic Mucinous Neoplasm." Surgery Journal 06, no. 02 (2020): e128-e130. http://dx.doi.org/10.1055/s-0040-1710342.

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AbstractIncidentally discovered pancreatic cysts have become more common with increasing use of abdominal cross-sectional imaging. Tools that help us to better risk stratify a pancreatic cyst include advanced imaging techniques, such as pancreatic protocol computed tomography (CT) scan or magnetic resonance imaging (MRI) with cholangiopancreatography. Endoscopic ultrasound (EUS) and fine-needle aspiration (FNA) are invasive measures to better define and sample cysts especially if high-risk features are present. EUS may also yield pancreatic cyst fluid for analysis of carcinoembryonic antigen (

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Cadili, Ali, Amy Bazzerelli, Sipi Garg, and Robert Bailey. "Survival in Cystic Neoplasms of the Pancreas." Canadian Journal of Gastroenterology 23, no. 8 (2009): 537–42. http://dx.doi.org/10.1155/2009/139780.

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BACKGROUND: The natural history of pancreatic cystic neoplasms remains poorly understood despite growing evidence on the subject. Pancreatic cysts display a wide spectrum of pathological phenotypes, each associated with a different prognostic implication. Many pancreatic cysts are of undetermined malignant potential at presentation and remain so until surgically resected. While the survival rates of patients with malignant cysts are known to be poor, survival rates in patients with undetermined pancreatic cysts are unknown.OBJECTIVE: To identify the factors associated with survival in a group

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Zhang, Mingjuan Lisa, and Martha B. Pitman. "Practical Applications of Molecular Testing in the Cytologic Diagnosis of Pancreatic Cysts." Journal of Molecular Pathology 2, no. 1 (2021): 11–22. http://dx.doi.org/10.3390/jmp2010002.

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Mucinous pancreatic cysts are precursor lesions of ductal adenocarcinoma. Discoveries of the molecular alterations detectable in pancreatic cyst fluid (PCF) that help to define a mucinous cyst and its risk for malignancy have led to more routine molecular testing in the preoperative evaluation of these cysts. The differential diagnosis of pancreatic cysts is broad and ranges from non-neoplastic to premalignant to malignant cysts. Not all pancreatic cysts—including mucinous cysts—require surgical intervention, and it is the preoperative evaluation with imaging and PCF analysis that determines p

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Singh, Ritu R., Harishankar Gopakumar, and Neil R. Sharma. "Diagnosis and Management of Pancreatic Cysts: A Comprehensive Review of the Literature." Diagnostics 13, no. 3 (2023): 550. http://dx.doi.org/10.3390/diagnostics13030550.

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The prevalence of pancreatic cysts has been rising due to the widespread use of cross-sectional imaging (CT scan and MRI) of the abdomen. While most pancreatic cysts are benign and do not require treatment or surveillance, a significant minority are premalignant and rarely malignant. The risk stratification of these lesions is not straightforward, and individual risk assessment, cyst size, distribution, and alarming morphologic features (when present) can guide the next steps in management. Neoplastic pancreatic cysts are mucinous or non-mucinous. Endoscopic ultrasound with fine-needle aspirat

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14

Oleśna, Aleksandra, Michał Wlaźlak, Janusz Strzelczyk, and Marian Danilewicz. "Pancreatic cysts or pancreatic cystic neoplasms? An analysis of 145 cases." Polish Journal of Surgery 90, no. 4 (2018): 1–4. http://dx.doi.org/10.5604/01.3001.0012.1267.

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Introduction Frequency of detection of pancreatic cystic lesions increased recent years. The majorities are pseudocysts, the remaining cysts are mainly neoplasms. Proven risk of malignancy affects intraductal papillary mucinous neoplasms (IPMN) and mucinous cystic neoplasms (MCN). Material and methods 145 patients operated on at the Department of General and Transplant Surgery in Barlicki Hospital in Lodz, Poland, in 2007-2016 due to pancreatic cystic lesion. The type of surgery, histopathological diagnosis and basic demographic data were analyzed. Results Nonneoplastic cyst (mainly pseudocyst

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Koo, Chieh Sian, and Khek-Yu Ho. "Endoscopic Ultrasound-Based Evaluation of Pancreatic Cysts: New Invasive Modalities." Korean Journal of Pancreas and Biliary Tract 27, no. 4 (2022): 145–49. http://dx.doi.org/10.15279/kpba.2022.27.4.145.

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Pancreatic cysts are a heterogenous group of lesions that can be differentiated into mucinous and non-mucinous cysts based on their malignant potential. Crosssectional imaging alone is inadequate to reliably distinguish between the two groups. Endoscopic ultrasound (EUS) and fine needle aspiration has been used for analysis of the cyst morphology and cyst fluid. Traditional markers such as fluid carcinoembryonic antigen and cytology have been useful particularly for the assessment of indeterminate cysts or those with high-risk features, but the overall diagnostic accuracy is still sub-par. As

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Malik, Praveen, Ewa Tyczkowska-Sieroń, Adam Durczyński, et al. "Microbiome in Pancreatic Fluid - Preliminary Analysis of Pancreatic Cystic Lesions." Lekarz Wojskowy 101, no. 4 (2023): 324–28. http://dx.doi.org/10.53301/lw/174341.

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Introduction and objectiveOne of the main precursory lesions for pancreatic carcinoma is pancreatic cystic neoplasm. Differentiation between the various types of cysts is a clinical challenge. The microbiome colonizing the pancreatic cyst fluid is mostly unknown. The aim of the study was microbiological assessment of pancreatic cysts compared with biochemical parameters and histopathological results.Material and methods30 patients with pancreatic cysts undergoing surgery in 2022-2023 at the Department of General and Transplant Surgery, Medical University of Lodz, were enrolled in the study. Pr

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Ivry, Sam L., Giselle M. Knudsen, Francesco Caiazza, et al. "The lysosomal aminopeptidase tripeptidyl peptidase 1 displays increased activity in malignant pancreatic cysts." Biological Chemistry 400, no. 12 (2019): 1629–38. http://dx.doi.org/10.1515/hsz-2019-0103.

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Abstract Incidental detection of pancreatic cysts has increased dramatically over the last decade, but risk stratification and clinical management remain a challenge. Mucinous cysts are precursor lesions to pancreatic cancer, however, the majority are indolent. Current diagnostics cannot identify mucinous cysts that harbor cancer or reliably differentiate these lesions from nonmucinous cysts, which present minimal risk of malignant progression. We previously determined that activity of two aspartyl proteases was increased in mucinous cysts. Using a global protease activity profiling technology

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Hnach, Youssef, Mohamed Tarchouli, Tarik Salaheddine, and Nourdin Aqodad. "ISOLATED POLYCYSTIC DISEASE OF THE PANCREAS: A CASE REPORT." International Journal of Advanced Research 10, no. 01 (2022): 197–99. http://dx.doi.org/10.21474/ijar01/14031.

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Polycysticdisease of the pancreasis a rare disease most often seen in association with polycystic kidney disease and Von Hippel Lindau syndrome. It is characterized by the presence of single or multiple simple congenital cysts in the pancreatic parenchyma. These cysts are benign in nature and do not communicate with the main pancreatic duct. We report a case of a young 31-year-old female patient incidentally detected to have multiple simple pancreatic cysts.

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Horný, Ivo, and Tomáš Hucl. "The role of molecular biology in the diff erential diagnosis of pancreatic cystic neoplasias." Gastroenterologie a hepatologie 75, no. 5 (2021): 417–23. http://dx.doi.org/10.48095/ccgh2021417.

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Summary: Pancreatic cysts have been detected ever more frequently in recent years due to the advanced and wider use of imaging methods. We find them on CT or MR also in asymptomatic patients who do not have a history of any pancreatic disease. Pancreatic cystic lesions represent a wide range of pathological changes from simple cysts through precancerous lesions to malignant cysts. Accurate diagnosis remains difficult despite the combination of clinical status evaluation, imaging findings, and biochemical and cytological examination. Molecular biological examination of cyst aspirate obtained

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Choi, Jun-Ho, Dong Seo, Tae Song, et al. "Long-term outcomes after endoscopic ultrasound-guided ablation of pancreatic cysts." Endoscopy 49, no. 09 (2017): 866–73. http://dx.doi.org/10.1055/s-0043-110030.

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Abstract Background and study aims The aim of this study was to investigate the long-term outcomes after endoscopic ultrasound (EUS)-guided pancreatic cyst ablation. Patients and methods In a single-center, prospective study, 164 patients with pancreatic cysts underwent EUS-guided cyst ablation using ethanol with paclitaxel. The inclusion criteria were as follows: unilocular or oligolocular cysts; clinically indeterminate cysts that required EUS fine-needle aspiration; and/or cysts that grew during the observation period. Treatment response was classified as complete resolution, partial resolu

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Gerasimov, Aleksandr, Valeriy Nikolskiy, Aleksandr Mitroshin, Sergey Frolov, and Ekaterina Titova. "COMPLICATIONS OF OPEN SURGICAL PROCEDURES IN PATIENTS WITH PANCREATIC CYSTS." Archiv Euromedica 11, no. 2 (2021): 53–55. http://dx.doi.org/10.35630/2199-885x/2021/11/2/13.

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The incidence of pancreatic cysts is constantly growing due to an increasing number of patients with a history of pancreatitis. Furthermore, complications after surgical interventions for pancreatic cysts occur in 30-40% of patients. Objective: to analyze the complications in patients with pancreatic cysts after open surgery. We observed 68 patients who underwent open surgical interventions: cystogastrostomy and cystojejunostomy. All patients with pancreatic cysts were divided into 2 groups depending on the type of procedure. In 27 patients (29%) of the first group cystogastrostomy and in 41 p

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Gerasimov, A. V., V. I. Nikolskiy, A. N. Mitroshin, and K. I. Sergatskiy. "Evaluation of the quality of electrochemical study in the diagnosis of infection of pancreatic cysts." Biomedical Photonics 13, no. 2 (2024): 4–8. http://dx.doi.org/10.24931/2413-9432-2024-13-2-4-8.

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The formation of pancreatic cysts is a serious complication of acute pancreatitis, chronic pancreatitis and pancreatic injuries. Joulemetry is an integral method for evaluating the electrochemical properties of biological objects. To date, this method has not been used in the study of the electrochemical properties of the contents of pancreatic cysts. The purpose of this study was to evaluate the effectiveness of electrochemical analysis in the detection of infection in the contents of necrotic pancreatic cysts. An electrochemical study of contents of necrotic pancreatic cysts carried out on 1

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Cobb, William, Jessica Marks, Tien-Anh Tran, and Armando Rosales. "Robotic surgical resection of a pancreatic dermoid cyst: Case report and review of literature of an extremely rare pancreatic neoplasm." Edorium Journal of Gastroenterology 10, no. 1 (2025): 11–16. https://doi.org/10.5348/100020g01wc2025cr.

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Introduction: Mature cystic teratomas, also called dermoid cysts, are benign, well-differentiated tumors originating from cells of all three dermal layers. Pancreatic dermoid cysts are extremely rare with the first published case by Kerr in 1918 and only 55 subsequent published cases since. Literature review was conducted using PubMed, Ovid, Clinical Key, Cochrane Library, Web of Science, and UpToDate; results were not limited by publication date. We reviewed the resulting literature to determine the incidence and prior reported cases, pathology, presentation, imaging findings, and management

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Springer, Simeon, David L. Masica, Marco Dal Molin, et al. "A multimodality test to guide the management of patients with a pancreatic cyst." Science Translational Medicine 11, no. 501 (2019): eaav4772. http://dx.doi.org/10.1126/scitranslmed.aav4772.

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Pancreatic cysts are common and often pose a management dilemma, because some cysts are precancerous, whereas others have little risk of developing into invasive cancers. We used supervised machine learning techniques to develop a comprehensive test, CompCyst, to guide the management of patients with pancreatic cysts. The test is based on selected clinical features, imaging characteristics, and cyst fluid genetic and biochemical markers. Using data from 436 patients with pancreatic cysts, we trained CompCyst to classify patients as those who required surgery, those who should be routinely moni

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Paramythiotis, Daniel, Antonia Syrnioti, Dimitrios Tsavdaris, et al. "Pancreatic Endometriosis Coexisting with a Splenic Mesothelial Cyst: A Rare Case Report and Review of the Literature." Diseases 13, no. 7 (2025): 203. https://doi.org/10.3390/diseases13070203.

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Endometriosis is a clinical entity affecting up to 10% of women of reproductive age, characterized by ectopic endometrial tissue outside the uterine cavity. While extrapelvic endometriosis has been documented, pancreatic endometriosis remains extremely rare and poses significant diagnostic challenges due to its similarity to other pancreatic diseases. At the same time, splenic mesothelial cysts are also rare and typically benign. This report presents a unique case of pancreatic endometriosis coexisting with a splenic mesothelial cyst in a 31-year-old woman. The patient presented to the emergen

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Liguory, Claude, Jean Francois Lefebvre, and Gary C. Vitale. "Endoscopic Drainage of Pancreatic Pseudocysts." Canadian Journal of Gastroenterology 4, no. 9 (1990): 568–71. http://dx.doi.org/10.1155/1990/963419.

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Endoscopic drainage of pancreatic pseudocysts was attempted in 17 patients over an eight year period. There were nine cysts located in the head of the pancreas, six in the body and two in the tail. Endoscopic retrograde cholangiopancreatography was performed in all cases and the pancreatic duct satisfactorily opacified in 16 of the 17 patients. This study identified a communication with the pancreatic duct in seven cases. There were two cases in which multiple cysts were present; in each, one cyst was drained endoscopically and the others surgically. Endoscopic drainage of the cyst was immedia

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Roda, C., J. Telford, K. Berg, and D. Sanders. "A243 CILIATED PANCREATIC FOREGUT CYST MIMICKING A MUCINOUS CYSTIC LESION: A CASE REPORT." Journal of the Canadian Association of Gastroenterology 8, Supplement_1 (2025): i100—i101. https://doi.org/10.1093/jcag/gwae059.243.

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Abstract Background Ciliated foregut cysts are rare congenital cysts that arise from the embryonic foregut and tracheobronchial tree, and are composed of an inner ciliated epithelium. While most commonly found in the mediastinum, they can also occur in the hepatopancreaticobiliary system. To our knowledge there has been less than 10 case reports describing ciliated pancreatic foregut cysts. Aims Report a case of a ciliated pancreatic foregut cyst and its associated imaging characteristics, cyst fluid analysis, and cytology. Methods A retrospective case report. Results A 66 year old female with

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Sokolov, Yurii Yu, Artem M. Efremenkov, Dmitrii V. Donskoy, et al. "Pancreatic cysts in children: diagnostical and surgical tactics." Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care 13, no. 2 (2023): 133–45. http://dx.doi.org/10.17816/psaic1506.

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BACKGROUND: Surgical treatment of pancreatic cysts is one of the most difficult procedures in pediatric surgery. In children with pancreatic cysts, the issues of differential diagnosis and determining the connection of the cyst cavity with the main pancreatic duct remain problematic. Recent publications have focused on the use of endoscopic ultrasonography in pediatric practice to visualize the parenchyma and the ductal system of the pancreas with high accuracy. AIM: This work aimed to study the results of treatment of children with cystic formations of the pancreas using modern radiatio

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Schechter, Shula, and Jiaqi Shi. "Simple Mucinous Cyst of the Pancreas: Review and Update." Archives of Pathology & Laboratory Medicine 141, no. 10 (2017): 1330–35. http://dx.doi.org/10.5858/arpa.2017-0232-ra.

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Context.— According to the 2014 Baltimore Consensus Meeting, simple mucinous cysts are defined as macroscopic cysts that are greater than 1 cm in size with gastric-type flat mucinous lining and minimal cytologic atypia without ovarian-type stroma. This lesion has not been widely recognized and has undergone a recent nomenclature change owing to unclear pathogenesis and biologic behavior. Mucinous pancreatic cystic lesions are generally considered precursor lesions of pancreatic adenocarcinoma. However, simple mucinous cysts generally have benign behavior with no recurrence or malignant transfo

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Buerlein, Ross C. D., and Vanessa M. Shami. "Management of pancreatic cysts and guidelines: what the gastroenterologist needs to know." Therapeutic Advances in Gastrointestinal Endoscopy 14 (January 2021): 263177452110457. http://dx.doi.org/10.1177/26317745211045769.

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The prevalence of pancreatic cysts has increased significantly over the last decade, partly secondary to increased quality and frequency of cross-sectional imaging. While the majority never progress to cancer, a small number will and need to be followed. The management of pancreatic cysts can be both confusing and intimidating due to the multiple guidelines with varying recommendations. Despite the differences in the specifics of the guidelines, they all agree on several high-risk features that should get the attention of any clinician when assessing a pancreatic cyst: presence of a mural nodu

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Gagushin, V. A. "Surgical treatment of pancreatic pseudocysts." Kazan medical journal 70, no. 6 (1989): 407–9. http://dx.doi.org/10.17816/kazmj101566.

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Clinically and morphologically the cyst is an intermediate stage between acute and chronic pancreatitis. In the early stage of the disease, i.e. in absence of capsule, pancreatic juice leakages in retroperitoneal tissue, small omental pouch, inside pancreatic parenchyma cannot be anatomically considered a cyst, but since they are initial substrate for its formation, they are eligible to be called cysts in unstable stage. According to some authors, in the early stages of cysts should be treated conservatively, while others believe that surgical treatment should be carried out immediately after

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Gambitta, Pietro, Paolo Aseni, Paola Fontana, et al. "Advantage of endoscopic-ultrasound-fine-needle aspiration associated to Sendai clinical guidelines in detecting the malignant risk in patients with undetermined pancreatic cysts: Long-term follow-up." International Journal of Hepatobiliary and Pancreatic Diseases 7, no. 2 (2017): 1–4. http://dx.doi.org/10.5348/ijhpd-2016-62-oa-18.

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Aims: Contradictory information exists on whether different clinical guidelines are effective in detecting the malignant risk in patients with pancreatic cysts. We have retrospectively evaluated the accuracy and the long-term outcome in patients with pancreatic cysts with a diameter ≥ 2 cm when indication for surgery was established by clinical evaluation of their malignant risk according to Sendai Clinical Guidelines associated to endoscopic-ultrasound-fine-needle aspiration. Material and Methods: Patients with pancreatic cysts with a diameter ≥2 cm were evaluated for their potential malignan

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Oakes, Scott. "An advanced clinical practitioner led pancreatic cyst surveillance service." International Journal for Advancing Practice 3, no. 2 (2025): 96–99. https://doi.org/10.12968/ijap.2024.0070.

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Pancreatic cysts are a common incidental finding on cross-sectional imaging. Certain cysts, such as the intraductal papillary mucinous neoplasms, carry malignant potential and require close monitoring. The purpose of surveillance is to detect lesions at an early stage when resection would be indicated. The surveillance of these pancreatic cysts is often complex and variable. This is largely because of their incidental diagnosis and the fact that they are seldom symptomatic. The author's trust recognised a need to centralise and standardise pancreatic cyst management, in line with the current i

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Malka, D., P. Hammel, V. Vilgrain, J.-F. Fléjou, J. Belghiti, and P. Bernades. "Chronic obstructive pancreatitis due to a pancreatic cyst in a patient with autosomal dominant polycystic kidney disease." Gut 42, no. 1 (1998): 131–34. http://dx.doi.org/10.1136/gut.42.1.131.

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Background—Autosomal dominant polycystic kidney disease, the most frequent inherited polycystic disease, is a systemic disorder characterised by the development of numerous and bilateral kidney cysts leading to chronic renal failure. Extrarenal cysts are located mainly in the liver but also in various organs including the pancreas. To our knowledge, complications of pancreatic cysts in this disease have never been reported.Patient—The first case of painful chronic obstructive pancreatitis due to a true pancreatic cyst in a patient with autosomal dominant polycystic kidney disease is reported.

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SHIMOYAMA, Takatoshi, Tatsuroh HARADA, Akira YOSHIDA, et al. "PANCREATIC CYSTS." Journal of the Japanese Practical Surgeon Society 46, no. 12 (1985): 1576–82. http://dx.doi.org/10.3919/ringe1963.46.1576.

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Gonda, Tamas A., Djuna L. Cahen, and James J. Farrell. "Pancreatic Cysts." New England Journal of Medicine 391, no. 9 (2024): 832–43. http://dx.doi.org/10.1056/nejmra2309041.

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Brewer Gutierrez, Olaya I., and Anne Marie Lennon. "Pancreatic Cysts." Medical Clinics of North America 103, no. 1 (2019): 163–72. http://dx.doi.org/10.1016/j.mcna.2018.08.004.

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Levy, Michael J. "Pancreatic cysts." Gastrointestinal Endoscopy 69, no. 2 (2009): S110—S116. http://dx.doi.org/10.1016/j.gie.2008.12.011.

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Barkin, Jodie A., and Jamie S. Barkin. "Pancreatic Cysts." Pancreas 46, no. 6 (2017): 735–41. http://dx.doi.org/10.1097/mpa.0000000000000831.

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Pitman, Martha Bishop, Kent Lewandrowski, Jian Shen, Dushyant Sahani, William Brugge, and Carlos Fernandez-del Castillo. "Pancreatic cysts." Cancer Cytopathology 118, no. 1 (2009): 1–13. http://dx.doi.org/10.1002/cncy.20059.

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Timmaraju, Venkata Arun, Sydney David Finkelstein, and Jonathan Adam Levine. "Analytical Validation of Loss of Heterozygosity and Mutation Detection in Pancreatic Fine-Needle Aspirates by Capillary Electrophoresis and Sanger Sequencing." Diagnostics 14, no. 5 (2024): 514. http://dx.doi.org/10.3390/diagnostics14050514.

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Pancreatic cystic disease, including duct dilation, represents precursor states towards the development of pancreatic cancer, a form of malignancy with relatively low incidence but high mortality. While most of these cysts (>85%) are benign, the remainder can progress over time, leading to malignant transformation, invasion, and metastasis. Cytologic diagnosis is challenging, limited by the paucity or complete absence of cells representative of cystic lesions and fibrosis. Molecular analysis of fluids collected from endoscopic-guided fine-needle aspiration of pancreatic cysts and dilated du

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Lazutkin, Maksim V., Sergey Y. Ivanusa, Dmitriy P. Shershen, and Alexandr A. Popov. "Modern drainage interventions in the surgical treatment pancreatic cyst." Russian Military Medical Academy Reports 39, no. 3 (2020): 82–85. http://dx.doi.org/10.17816/rmmar64989.

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Purpose. To evaluate the capabilities of modern minimally invasive interventions under the beam guidance in the surgical treatment of pancreatic cysts. Materials and Methods. The results of the examination and treatment of 88 patients with pancreatic cysts. Percutaneous puncture drainage under ultrasonographic guidance holds 56 patients, endoscopic transmural drainage of cysts by ultrasonography- in 32. Results. After performing percutaneous drainage of cysts positive results were observed in 42 (75,0%) patients. Relapses cystic formations were observed in 14 (25.0%) patients. Endo

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Patel, Neel B., Parth Patel, and Jagdishkumar B. Patel. "Hydatid cyst in the tail of the pancreas: a rare case report." International Surgery Journal 11, no. 11 (2024): 1944–47. http://dx.doi.org/10.18203/2349-2902.isj20243265.

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Hydatid cysts, caused by Echinococcus granulosus, are rare but significant when found in the pancreas, particularly in endemic regions. This case report discusses a 32-year-old female with a pancreatic tail cyst presenting with epigastric pain and intermittent fever. Diagnostic imaging, contrast enhanced computed tomography (CECT) and magnetic resonance cholangiopancreatography (MRCP), and serological tests were inconclusive, making preoperative diagnosis challenging. Differential diagnoses included pancreatic pseudocysts, benign neoplasms, abscesses, and other cystic lesions. The patient unde

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Langan, Russell C., Henry A. Pitt, and Erika Schneider. "Role of artificial intelligence in pancreatic cystic neoplasms: modernizing the identification and longitudinal management of pancreatic cysts." Artificial Intelligence Surgery 3, no. 2 (2023): 140–46. http://dx.doi.org/10.20517/ais.2023.13.

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Mucinous cysts of the pancreas represent the most common identifiable precursor to pancreatic cancer. Evidence-based guidelines for screening and surveillance exist, but many patients are either not properly identified or lost to follow-up. Artificial Intelligence, specifically computational linguistics models, can dramatically improve patient identification and mitigate risk through modernizing pancreatic cyst longitudinal surveillance. Herein we discuss the risk associated with mucinous cysts of the pancreas and modern approaches to patient identification and follow-up.

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Pins, M. R., C. C. Compton, J. F. Southern, D. W. Rattner, and K. B. Lewandrowski. "Ciliated Enteric Duplication Cyst Presenting as A Pancreatic Cystic Neoplasm: Report of A Case with Cyst Fluid Analysis." Clinical Chemistry 38, no. 8 (1992): 1501–3. http://dx.doi.org/10.1093/clinchem/38.8.1501.

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Abstract Pancreatic cysts include inflammatory pseudocysts, cystic tumors (serous and mucinous), and various rare cystic lesions. We report a case of a ciliated enteric duplication cyst that presented on computed tomographic scan as a pancreatic cystic neoplasm. Cyst fluid analysis revealed markedly increased concentrations of carcinoembryonic antigen and CA 125 and increased fluid viscosity. These features are typical for a mucinous cystic neoplasm of the pancreas and demonstrate a potential pitfall associated with the diagnosis of pancreatic cysts by chemical analyses. Enteric duplications i

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Sand, J., and I. Nordback. "The Differentiation between Pancreatic Neoplastic Cysts and Pancreatic Pseudocyst." Scandinavian Journal of Surgery 94, no. 2 (2005): 161–64. http://dx.doi.org/10.1177/145749690509400213.

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The number of small and often asymptomatic cystic lesions detected in pancreas has increased during the last decade. Historically the vast majority of the pancreatic cystic lesions were considered pseudocysts, but in recent series the incidence of various neoplastic cysts, such as intraductal papillary mucinous neoplasm, serous cystadenomas and cystic endocrine tumours, has increased. The possible malignant potential in these cystic neoplasms warrants careful diagnostic workup to choose the optimal treatment for each patient. Patient's age, symptoms and a possible history of acute or chronic p

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Jabłońska, Beata. "Pancreatic cysts: etiology, diagnosis and management." Open Medicine 9, no. 1 (2014): 92–107. http://dx.doi.org/10.2478/s11536-013-0244-8.

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AbstractPancreatic cysts involve a wide spectrum of pathologies from post-inflammatory cysts to malignant neoplasms. Pancreatic pseudocysts, serous cystadenomas, mucinous cystadenomas, intraductal papillary mucinous neoplasms (IPMNs) and solid pseudopapillary tumors occur most frequently. Differential diagnosis involves the following imaging investigations: transabdominal ultrasonography (TUS), contrast enhanced ultrasonography (CEUS) and endoscopic ultrasonography (EUS), computed tomography (CT), magnetic resonance (MR) and magnetic resonance cholangiopancretography (MRCP), endoscopic retrogr

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Levy, Alexandre, Theodora Popovici, and Phuong-Nhi Bories. "Tumor Markers in Pancreatic Cystic Fluids for Diagnosis of Malignant Cysts." International Journal of Biological Markers 32, no. 3 (2017): 291–96. http://dx.doi.org/10.5301/jbm.5000257.

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Background and aim Early diagnosis of premalignant or malignant pancreatic cysts is essential to improve prognosis. Sampling of pancreatic cyst fluid by fine-needle aspiration during endoscopic ultrasonography (EUS) enables cytopathological examination combined with biochemical analysis. This study aimed to provide an aid based on biological markers for the preoperative management of patients with pancreatic cysts. Methods Pancreatic fluids obtained by EUS-guided fine-needle aspiration from 115 patients with cystic lesions were assayed for amylase, lipase, carcinoembryonic antigen (CEA), CA 19

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Joshi, Virendra, Dominic Guanzon, Cris Molina, Zarin Nuzhat, Gregory Rice, and Carlos saloman Gallo. "Exosomal miRNA signature of pancreatic cyst: Liquid biopsies as indicators of pancreatic cancer." Journal of Clinical Oncology 36, no. 4_suppl (2018): 225. http://dx.doi.org/10.1200/jco.2018.36.4_suppl.225.

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225 Background: Pancreatic cysts are a group of lesions with malignant potential. Currently, there are no consistently reliable biomarkers or imaging modalities to accurately predict biologic behavior of these cysts. We tested the hypothesis that tumor-derived exosomes (better conserved than free miRNA) can be acquired endoscopically from pancreatic cyst fluid and may allow for improved distinction between benign, premalignant and malignant cysts. Methods: Exosomes were isolated and characterised by differential and buoyant centrifugation from pancreatic cyst fluid obtained from 30 patients wi

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Thomas, Mini, Daniel Sheik, Kaleb Byers, U. Chinna Rajesh, Curtis Ramsey, and V. Jo Davisson. "Amplified Sciences PanCyst Pro Panel to accurately identify non-mucinous pancreatic cyst fluid." Journal of Clinical Oncology 42, no. 3_suppl (2024): 617. http://dx.doi.org/10.1200/jco.2024.42.3_suppl.617.

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617 Background: Pancreatic cysts are rarely symptomatic, and, consequently, are detected incidentally during routine imaging analyses for unrelated disorders. Guidelines for diagnosis of pancreatic cysts rely on imaging and supportive analyses of fluid extracted during endoscopic ultrasound with fine-needle aspiration (EUS-FNA). Unfortunately, currently available protein markers and assays are not sufficiently accurate to rule-out patients in whom a non-mucinous pancreatic cyst has formed. Since non-mucinous pancreatic cysts seldom progress to cancer, this patient population is at risk of bein

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