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1

Haas, Sarah K., Virginia Hayssen, and Paul R. Krausman. "Panthera leo." Mammalian Species 762 (July 2005): 1–11. http://dx.doi.org/10.1644/1545-1410(2005)762[0001:pl]2.0.co;2.

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2

Murali, Manohar Yadav*1 Ankit Srivastava2 Kriti Nigam2 &. Vijay K. Yadav2. "COMPARATIVE ANALYSIS OF WILD ANIMAL HAIRS." GLOBAL JOURNAL OF ENGINEERING SCIENCE AND RESEARCHES 5, no. 11 (2018): 239–45. https://doi.org/10.5281/zenodo.1544939.

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The present study was conducted to find out the macroscopic and microscopic characteristics of hair of nine endangered wild animals with the objective of species identification. Hairs remain unchanged chemically and histologically till several years. In present study the shredded hair sample of Bear (<em>Melursus ursinus</em>), Hyena (<em>Crocuta crocuta</em>), Lioness (<em>Panthera leo</em>), Lion (<em>Panthera leo</em>), Zebra (<em>Equus quagga</em>), Panther (<em>Panthera pardus</em>), Blackbuck (<em>Antilope cervicapra</em>), Sambar deer (<em>Rusa unicolor</em>) and Fishing cat (<em>Priona
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3

Diedrich , Cajus G. "Pleistocene Panthera leo spelaea (g." Quaternaire, no. 22/2 (June 1, 2011): 105–27. http://dx.doi.org/10.4000/quaternaire.5897.

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4

Christiansen, Per. "Distinguishing skulls of lions (Panthera leo) and tigers (Panthera tigris)." Mammalian Biology 73, no. 6 (2008): 451–56. http://dx.doi.org/10.1016/j.mambio.2007.08.001.

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5

Mozos, E., P. Ginel, A. Diz, et al. "Otolithiasis in African Lions (Panthera leo)." Journal of Comparative Pathology 150, no. 1 (2014): 124. http://dx.doi.org/10.1016/j.jcpa.2013.11.199.

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6

MOTA DA COSTA, ANDRE LUIZ, Rodrigo Hidalgo Friciello Teixeira, Natache Arouca Garofalo, and Diogo Tosi. "CARCINOMA ADRENAL EM LEOA (Panthera leo)." Veterinária e Zootecnia 31 (December 9, 2024): 1–6. https://doi.org/10.35172/rvz.2024.v31.1653.

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A ocorrência de tumores em felídeos selvagens aumentou nos últimos anos devido a maior longevidade dos animais mantidos sob cuidados humanos. No entanto, a ocorrência de tumores adrenais é baixa. Em leão (Panthera leo) há apenas um relato de adenoma adrenal. A maioria dos tumores adrenais induz ao desequilíbrio dos hormônios adrenais, sejam glicocorticoides (cortisol), mineralocorticoides (aldosterona) ou hormônios sexuais. Quando há aumento de cortisol, os sintomas são originários dos efeitos imunossupressores, anti-inflamatórios e catabólicos dos glicocorticoides. Já o aumento da produção de
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7

Libert, Cédric, Christophe Ravel, Francine Pratlong, Patrick Lami, Jacques Dereure, and Nicolas Keck. "LEISHMANIA INFANTUMINFECTION IN TWO CAPTIVE BARBARY LIONS (PANTHERA LEO LEO)." Journal of Zoo and Wildlife Medicine 43, no. 3 (2012): 685–88. http://dx.doi.org/10.1638/2012-0056.1.

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8

Vankova, Lenka, Johana Alaverdyan, and Daniel Vanek. "Developmental Validation of DNA Quantitation System, Extended STR Typing Multiplex, and Database Solutions for Panthera leo Genotyping." Life 15, no. 4 (2025): 664. https://doi.org/10.3390/life15040664.

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This study describes the development of a species determination/DNA quantification system called Pleo Qplex and an individual identification STR multiplex called Pleo STRplex using Panthera leo samples. Pleo Qplex enables us to measure the quantity of extracted nuclear and mitochondrial DNA and detect the presence of co-purified inhibitors. Pleo STRplex, consisting of seven loci, enables the determination of the DNA profile from a sample of Panthera leo based on the analysis of short tandem repeats (STRs). The Pleo STRplex provides additional loci on top of previously published STR loci in Pti
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9

Metter, J. E. Van, M. Dana Harriger, and Rosina H. Bolen. "Environmental enrichment utilizing stimulus objects for African lions (Panthera leo leo) and Sumatran tigers (Panthera tigris sumatrae)." BIOS 79, no. 1 (2008): 7–16. http://dx.doi.org/10.1893/0005-3155(2008)79[7:eeusof]2.0.co;2.

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10

Lucena, Ricardo B., Rafael A. Fighera, and Claudio S. L. Barros. "Cistos peribiliares em leão-africano (Panthera leo)." Pesquisa Veterinária Brasileira 31, no. 2 (2011): 165–68. http://dx.doi.org/10.1590/s0100-736x2011000200012.

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São descritos os achados macroscópicos e histopatológicos de cistos peribiliares em uma fêmea adulta de leão-africano (Panthera leo). Macroscopicamente, todos os lobos hepáticos continham numerosos cistos preenchidos por líquido translúcido. Histologicamente, os cistos estavam localizados no hilo hepático e nos tratos portais. Os cistos eram revestidos internamente por epitélio simples, constituído por células colunares ou cuboidais e não mucinosas, de acordo com avaliação para ácido periódico de Schiff/azul alciano. Na imuno-histiquímica, todas as células desse epitélio foram positivas para c
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11

Bizari, Thiago G., Betina F. Lautert, and Renato S. de Sousa. "Biliary cystadenoma in a lion (Panthera leo)." Brazilian Journal of Veterinary Pathology 15, no. 1 (2022): 54–56. http://dx.doi.org/10.24070/bjvp.1983-0246.v15i1p54-56.

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Animals in human care often exceed the life expectancy of animals in the wild when they have veterinarian follow-ups, no competition for space or food, and continuous care. Advanced age favors the development of mutations that often trigger cancer, which sometimes causes death. There are reports in the literature on neoplasms in lions in the liver, which are one of the main organs affected. A 20-year-old lion specimen was received for necropsy at the Federal University of Paraná, Curitiba, Brazil. Multiple cystic dilations were observed in the liver. Histologically, they were internally covere
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12

Tucker, Alison R., Edward C. Ramsay, and Robert L. Donnell. "Oligodendroglioma in an African Lion (Panthera leo)." Journal of Zoo and Wildlife Medicine 39, no. 4 (2008): 650–54. http://dx.doi.org/10.1638/2007-0097.1.

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13

Martella, Vito, Marco Campolo, Eleonora Lorusso, et al. "Norovirus in Captive Lion Cub (Panthera leo)." Emerging Infectious Diseases 13, no. 7 (2007): 1071–73. http://dx.doi.org/10.3201/eid1307.070268.

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14

Harrison, T. M., C. A. McKnight, J. G. Sikarskie, et al. "Malignant Lymphoma in African Lions (Panthera Leo)." Veterinary Pathology 47, no. 5 (2010): 952–57. http://dx.doi.org/10.1177/0300985810375054.

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15

Jayakumar, C. S., Swapna Susan Abraham, and D. Sanjay. "Congenital megacolon in a Lion (Panthera leo)." Zoos' Print Journal 20, no. 9 (2005): 1998. http://dx.doi.org/10.11609/jott.zpj.1365.1998.

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16

Hayward, Matt W., and Graham I. H. Kerley. "Prey preferences of the lion ( Panthera leo )." Journal of Zoology 267, no. 03 (2005): 309. http://dx.doi.org/10.1017/s0952836905007508.

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17

Gjurovski, I., T. Ristoski, S. Kostadinova Kunovska, J. Milosevski, and V. Levajkovic-Trajkov. "Facial Myxofibrosarcoma in a Lion (Panthera leo)." Journal of Comparative Pathology 174 (January 2020): 197. http://dx.doi.org/10.1016/j.jcpa.2019.10.184.

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18

Chandra, A. M. Sundeep, Rebecca E. Papendick, Juergen Schumacher, Bruce L. Homer, and Paul Wollenman. "Cerebellar Herniation in Captive Lions (Panthera Leo)." Journal of Veterinary Diagnostic Investigation 11, no. 5 (1999): 465–68. http://dx.doi.org/10.1177/104063879901100514.

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19

Leonardi, L., E. Lepri, S. Nannarone, and O. Mechelli. "Fibroblastic osteosarcoma in a lion (Panthera leo)." Open Veterinary Journal 5, no. 2 (2014): 1. http://dx.doi.org/10.5455/ovj.2014.v4.i1.p1.

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This report describes a case of spontaneous fibroblastic osteosarcoma in the humerus of a lion from a private park in Perugia, Italy. The tumor had an irregular, smooth, brown surface and a generally firm, rubbery consistence with gritty to hard areas interspersed. The mass was poorly vascularized with areas of necrosis at the periphery. The cut surface showed a multilobulated mass that had breached the humeral cortex, with periosteal production of reactive bone. The mass invaded the epiphysis, the synovial membrane, the joint capsule and ligaments. A mild hemorrhagic effusion appeared in the
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20

Larsson, Maria Helena Matiko Akao, Auddrey Sismotto Flores, José Daniel Luzes Fedullo, et al. "Biochemical parameters of wild felids (Panthera leo and Panthera tigris altaica) kept in captivity." Semina: Ciências Agrárias 38, no. 2 (2017): 791. http://dx.doi.org/10.5433/1679-0359.2017v38n2p791.

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Most populations of wild felines are now considered endangered or near extinction due to the indiscriminate hunting and the reduction of their natural habitat, caused by man. Due to the limited number of animals within a population, these species are especially vulnerable to the impacts of diseases and endogamy. In addition, wild felines are also susceptible to metabolic and behavioral changes related to a change in their natural conditions, habitat, and feeding, when the animal enters into captivity. There are few descriptions in the literature of the serum biochemistries of lions and tigers.
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21

Costa, Eliesse Pereira, Fabiano da Silva Flores, Guilherme Rech Cassanego, Priscila Inês Ferreira, Josiele Milena de Souza, and Luciana Silveira Flôres. "Aspectos morfológicos da glândula molar em leão (Panthera leo)/ Morphological aspects of the molar gland in lion (Panthera leo)." Brazilian Journal of Development 7, no. 9 (2021): 87614–21. http://dx.doi.org/10.34117/bjdv7n9-090.

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22

de Manuel, Marc, Ross Barnett, Marcela Sandoval-Velasco, et al. "The evolutionary history of extinct and living lions." Proceedings of the National Academy of Sciences 117, no. 20 (2020): 10927–34. http://dx.doi.org/10.1073/pnas.1919423117.

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Lions are one of the world’s most iconic megafauna, yet little is known about their temporal and spatial demographic history and population differentiation. We analyzed a genomic dataset of 20 specimens: two ca. 30,000-y-old cave lions (Panthera leo spelaea), 12 historic lions (Panthera leo leo/Panthera leo melanochaita) that lived between the 15th and 20th centuries outside the current geographic distribution of lions, and 6 present-day lions from Africa and India. We found that cave and modern lions shared an ancestor ca. 500,000 y ago and that the 2 lineages likely did not hybridize followi
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23

Lucena, Ricardo B., Rafael A. Fighera, Adriano B. Carregaro, Maria Andréia Inkelmann, and Claudio S. L. Barros. "Carcinoma bronquíolo-alveolar em leão-africano (Panthera leo)." Pesquisa Veterinária Brasileira 30, no. 6 (2010): 479–83. http://dx.doi.org/10.1590/s0100-736x2010000600002.

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Um caso de carcinoma bronquíolo-alveolar difuso do tipo misto foi diagnosticado em um leão-africano (Panthera leo), hospitalizado com sinais de dispnéia e emagrecimento progressivo. Em todos os lobos pulmonares havia múltiplos nódulos esbranquiçados, macios e homogêneos, de 0,2-0,5cm em diâmetro. Histologicamente, os nódulos eram constituídos por células neoplásicas arranjadas em alvéolos e papilas sustentados por moderado estroma fibrovascular, um padrão que lembrava a estrutura pulmonar pré-existente. Na reação pelo ácido periódico de Schiff (PAS) foi observada marcação positiva no citoplasm
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24

Ricci, Emanuele, Paolo Cavicchio, and Carlo Cantile. "Fibrocartilaginous Embolic Myelopathy in a Lion (Panthera leo)." Journal of Zoo and Wildlife Medicine 41, no. 2 (2010): 334–37. http://dx.doi.org/10.1638/2009-0101r.1.

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25

Andersen,, K. F. "Urinary Volatile Constituents of the Lion, Panthera leo." Chemical Senses 24, no. 2 (1999): 179–89. http://dx.doi.org/10.1093/chemse/24.2.179.

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26

Hartman, Marthinus J., Eric Monnet, Robert M. Kirberger, et al. "Laparoscopic Sterilization of the African Lioness (Panthera leo)." Veterinary Surgery 42, no. 5 (2013): 559–64. http://dx.doi.org/10.1111/j.1532-950x.2012.01049.x.

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27

Smuts, G. L., J. L. Anderson, and J. C. Austin. "Age determination of the African lion (Panthera leo)." Journal of Zoology 185, no. 1 (2009): 115–46. http://dx.doi.org/10.1111/j.1469-7998.1978.tb03317.x.

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28

Garcia-Gonzalez Beatriz, B., and N. Cuesta-Garcia. "Multiseptate Gallbladder in an African Lioness (Panthera leo)." Journal of Comparative Pathology 148, no. 1 (2013): 89. http://dx.doi.org/10.1016/j.jcpa.2012.11.175.

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29

Sharma, Anil K., Monalisa Sahoo, and M. Karikalan. "Cloisonné kidney in an Asiatic lion (Panthera leo)." Indian Journal of Veterinary Pathology 39, no. 3 (2015): 293. http://dx.doi.org/10.5958/0973-970x.2015.00073.5.

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30

Ruiz de Ybanez, M. R., C. Martinez-Carrasco, J. J. Martinez, J. M. Ortiz, T. Attout, and O. Bain. "Dirofilaria immitis in an African lion (Panthera leo)." Veterinary Record 158, no. 7 (2006): 240–42. http://dx.doi.org/10.1136/vr.158.7.240.

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31

Argant, Alain, and Jean-Philip Brugal. "The cave lion Panthera (Leo) spelaea and its evolution: Panthera spelaea intermedia nov. subspecies." Acta Zoologica Cracoviensia 60, no. 2 (2017): 58–103. http://dx.doi.org/10.3409/azc.60_2.59.

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32

Kumar, Vijay, and Anshu Raj. "Management of wound myiasis in a lion (panthera leo)." International Journal for Agro Veterinary and Medical Sciences 6, no. 1 (2012): 4. http://dx.doi.org/10.5455/ijavms.11680.

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33

Montellano-Ballesteros, Marisol, and Gerardo Carbot-Chanona. "Panthera leo atrox (Mammalia: Carnivora: Felidae) in Chiapas, Mexico." Southwestern Naturalist 54, no. 2 (2009): 217–22. http://dx.doi.org/10.1894/clg-20.1.

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34

Murer, L., M. B. Ribeiro, L. Machado, et al. "Piometra em uma leoa (Panthera leo): relato de caso." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 67, no. 3 (2015): 727–31. http://dx.doi.org/10.1590/1678-4162-8154.

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A piometra é uma infecção aguda ou crônica do útero que ocorre frequentemente em cadelas não castradas, podendo também ocorrer em gatas domésticas e selvagens, sendo poucos os estudos relacionados à piometra em grandes felídeos. O objetivo deste relato foi descrever um caso de piometra em uma leoa (Panthera leo) de cativeiro, as lesões de necropsia e histológicas, bem como os resultados da análise microbiológica. Uma leoa com aproximadamente 23 anos, pertencente a um criadouro conservacionista de Santa Maria-RS, foi encontrada morta pela manhã em seu recinto. Após coleta de dados, procedeu-se
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35

Bharathidasan, Murugan, Benjamin Justin William, Ramamurthy Jayaprakash, Thandavan Arthanari Kannan, Rajarthanam Thirumurugan, and Ravi Sundar George. "Immobilization and Anaesthesia in Asiatic Lions (Panthera leo persica)." Advances in Animal and Veterinary Sciences 4, no. 3 (2016): 134–44. http://dx.doi.org/10.14737/journal.aavs/2016/4.3.134.144.

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36

Dolrenry, Stephanie, Jennifer Stenglein, Leela Hazzah, R. Scott Lutz, and Laurence Frank. "A Metapopulation Approach to African Lion (Panthera leo) Conservation." PLoS ONE 9, no. 2 (2014): e88081. http://dx.doi.org/10.1371/journal.pone.0088081.

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37

Scaglione, F. E., C. Schröder, G. Degiorgi, O. Zeira, and E. Bollo. "Cranial Malformations in Related White Lions (Panthera leo krugeri)." Veterinary Pathology 47, no. 6 (2010): 1095–99. http://dx.doi.org/10.1177/0300985810382518.

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38

Das, Dilip Kumar, G. Srinivas Murthy, and Narayana Bhattacherjee. "Management of posterior paresis in a lion (Panthera leo)." Zoos' Print Journal 20, no. 3 (2005): 1822. http://dx.doi.org/10.11609/jott.zpj.1134.1822.

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39

Ravindran, Reghu, Bindu Lakshmanan, S. Anoop, T. S. Rajeev, and C. N. Dinesh. "Parasitic infection in captive lions (Panthera leo) at Wyanad." Zoos' Print Journal 21, no. 4 (2006): 2230. http://dx.doi.org/10.11609/jott.zpj.1438.2230.

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40

Eloff, F. C. "THE LIFE OF THE KALAHARI LION (PANTHERA LEO VERNAYI)." Transactions of the Royal Society of South Africa 53, no. 2 (1998): 267–69. http://dx.doi.org/10.1080/00359199809520393.

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41

Bollo, E., F. E. Scaglione, M. Tursi, et al. "Malignant pleural mesothelioma in a female Lion (Panthera leo)." Research in Veterinary Science 91, no. 1 (2011): 116–18. http://dx.doi.org/10.1016/j.rvsc.2010.08.005.

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42

Bruche, Susann, Markus Gusset, Sebastian Lippold, et al. "A genetically distinct lion (Panthera leo) population from Ethiopia." European Journal of Wildlife Research 59, no. 2 (2012): 215–25. http://dx.doi.org/10.1007/s10344-012-0668-5.

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43

Negrini, J., R. Guerra, J. Ruiz, et al. "Multiple Malformations in Non-related Captive Lions (Panthera leo)." Journal of Comparative Pathology 148, no. 1 (2013): 89. http://dx.doi.org/10.1016/j.jcpa.2012.11.174.

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44

Karlstam, E., and M. Goczkowski. "Syringomyelia in Two Asian Lion (Panthera leo persica) Siblings." Journal of Comparative Pathology 154, no. 1 (2016): 100. http://dx.doi.org/10.1016/j.jcpa.2015.10.106.

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45

Vercammen, F., No author No author, J. Brandt, L. Brantegem, and L. Ducatelle. "Haemangiosarcoma in a captive Asiatic lion (Panthera leo persica)." Open Veterinary Journal 5, no. 2 (2015): 52. http://dx.doi.org/10.5455/ovj.2015.v5.i1.p52.

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A 2.7-year-old male captive Asiatic lion (Panthera leo persica) died unexpectedly without preceding symptoms. Gross necropsy revealed liver and lung tumours, which proved to be haemangiosarcomas by histopathology. Some of the liver tumours were ruptured, leading to massive intra-abdominal haemorrhage and death. Haemangiosarcomas are rare in domestic and exotic felids, occurring in skin, thoracic-abdominal cavity and bones. Although these tumours mainly appear to be occurring in older cats, they are sometimes observed in younger animals, as in the present case. This is the first description of
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46

Schramm, Ralph Dee, Michael B. Briggs, and Jerry J. Reeves. "Spontaneous and induced ovulation in the lion (Panthera leo)." Zoo Biology 13, no. 4 (1994): 301–7. http://dx.doi.org/10.1002/zoo.1430130403.

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47

Tende, Talatu, Staffan Bensch, Ulf Ottosson, and Bengt Hansson. "Dual phylogenetic origins of N igerian lions ( Panthera leo )." Ecology and Evolution 4, no. 13 (2014): 2668–74. http://dx.doi.org/10.1002/ece3.1116.

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48

Meoli, R., C. Eleni, P. Cavicchio, et al. "B-cell chronic lymphocytic leukaemia in an African lion (Panthera leo)." Veterinární Medicína 63, No. 9 (2018): 433–37. http://dx.doi.org/10.17221/144/2017-vetmed.

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A 15-year-old female African lion (Panthera leo) maintained at the Zoological Garden of Pistoia, Tuscany (Italy), showed signs of malaise, dyspnoea, tremors, pale mucous membranes and ataxia for two days prior to death. Complete blood count showed anaemia, thrombocytopaenia and severe lymphocytosis. At autopsy, the most relevant finding was severe, generalised splenomegaly. Histologically, high numbers of neoplastic lymphocytes diffusely infiltrated the spleen, liver, heart, pancreas, kidney and lungs. The lymphoid cells were positive for CD79a and negative for CD3 on immunohistochemistry. The
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49

Larsson, Maria Helena M. A., Fernanda M. Coelho, Valéria M. C. Oliveira, et al. "Electrocardiographic Parameters of Captive Lions (Panthera leo) and Tigers (Panthera tigris) Immobilized with Ketamine Plus Xylazine." Journal of Zoo and Wildlife Medicine 39, no. 3 (2008): 314–19. http://dx.doi.org/10.1638/2007-0028.1.

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50

Duarte, Margarida D., Sílvia C. Barros, Margarida Henriques, et al. "Fatal Infection with Feline Panleukopenia Virus in Two Captive Wild Carnivores (Panthera tigris and Panthera leo)." Journal of Zoo and Wildlife Medicine 40, no. 2 (2009): 354–59. http://dx.doi.org/10.1638/2008-0015.1.

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