Relevant bibliographies by topics / Paper-based microfluidics

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters
  4. Conference papers

Academic literature on the topic 'Paper-based microfluidics'

Author: Grafiati
Published: 4 June 2021
Last updated: 14 February 2022

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Journal articles on the topic "Paper-based microfluidics"

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Soum, Veasna, Sooyong Park, Albertus Ivan Brilian, Oh-Sun Kwon, and Kwanwoo Shin. "Programmable Paper-Based Microfluidic Devices for Biomarker Detections." Micromachines 10, no. 8 (2019): 516. http://dx.doi.org/10.3390/mi10080516.

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Recent advanced paper-based microfluidic devices provide an alternative technology for the detection of biomarkers by using affordable and portable devices for point-of-care testing (POCT). Programmable paper-based microfluidic devices enable a wide range of biomarker detection with high sensitivity and automation for single- and multi-step assays because they provide better control for manipulating fluid samples. In this review, we examine the advances in programmable microfluidics, i.e., paper-based continuous-flow microfluidic (p-CMF) devices and paper-based digital microfluidic (p-DMF) devices, for biomarker detection. First, we discuss the methods used to fabricate these two types of paper-based microfluidic devices and the strategies for programming fluid delivery and for droplet manipulation. Next, we discuss the use of these programmable paper-based devices for the single- and multi-step detection of biomarkers. Finally, we present the current limitations of paper-based microfluidics for biomarker detection and the outlook for their development.
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Abadian, Arash, and Shahin Jafarabadi-Ashtiani. "Paper-based digital microfluidics." Microfluidics and Nanofluidics 16, no. 5 (2014): 989–95. http://dx.doi.org/10.1007/s10404-014-1345-7.

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Niedl, Robert R., and Carsten Beta. "Hydrogel-driven paper-based microfluidics." Lab on a Chip 15, no. 11 (2015): 2452–59. http://dx.doi.org/10.1039/c5lc00276a.

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Dungchai, Wijitar, Orawon Chailapakul, and Charles S. Henry. "Electrochemical Detection for Paper-Based Microfluidics." Analytical Chemistry 81, no. 14 (2009): 5821–26. http://dx.doi.org/10.1021/ac9007573.

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Choi, Gihoon, and Seokheun Choi. "Cellular flow in paper-based microfluidics." Sensors and Actuators B: Chemical 237 (December 2016): 1021–26. http://dx.doi.org/10.1016/j.snb.2015.11.127.

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Shen, Liu‐Liu, Gui‐Rong Zhang, and Bastian J. M. Etzold. "Paper‐Based Microfluidics for Electrochemical Applications." ChemElectroChem 7, no. 1 (2019): 10–30. http://dx.doi.org/10.1002/celc.201901495.

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Kaya, Kerem, Ahmet Yasin Celik, and Senol Mutlu. "Integration of Paper Based Electro-Osmotic Pumps to Continuous Microfluidic Channels." Proceedings 2, no. 13 (2018): 870. http://dx.doi.org/10.3390/proceedings2130870.

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This work reports for the first-time integration of continuous microfluidic channels to the paper-based electro-osmotic pumps (EOPs) with liquid bridges. In addition, 0.2 μm pore sized cellulose acetate (CA) membrane filter is used to eliminate pressure-driven flow instead of filter paper which is common in paper microfluidics and has an average pore size of 10 μm. A factor of 57 increase in hydraulic resistance is achieved with the new paper. Fabrication of the pumps and microfluidic channels using paper, wax, adhesive film and PMMA plates is explained. Volumetric flow rate of 19 nL/min is achieved in the microfluidic system with 61 V/cm electrical field magnitude applied to DI water. The capability of the integrated system is shown with precise liquid motion in a Y-shaped microfluidic channel integrated with two EOPs.
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Liu, Bingwen, Dan Du, Xin Hua, Xiao-Ying Yu, and Yuehe Lin. "Paper-Based Electrochemical Biosensors: From Test Strips to Paper-Based Microfluidics." Electroanalysis 26, no. 6 (2014): 1214–23. http://dx.doi.org/10.1002/elan.201400036.

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Gorgannezhad, Lena, Helen Stratton, and Nam-Trung Nguyen. "Microfluidic-Based Nucleic Acid Amplification Systems in Microbiology." Micromachines 10, no. 6 (2019): 408. http://dx.doi.org/10.3390/mi10060408.

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Rapid, sensitive, and selective bacterial detection is a hot topic, because the progress in this research area has had a broad range of applications. Novel and innovative strategies for detection and identification of bacterial nucleic acids are important for practical applications. Microfluidics is an emerging technology that only requires small amounts of liquid samples. Microfluidic devices allow for rapid advances in microbiology, enabling access to methods of amplifying nucleic acid molecules and overcoming difficulties faced by conventional. In this review, we summarize the recent progress in microfluidics-based polymerase chain reaction devices for the detection of nucleic acid biomarkers. The paper also discusses the recent development of isothermal nucleic acid amplification and droplet-based microfluidics devices. We discuss recent microfluidic techniques for sample preparation prior to the amplification process.
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Meredith, Nathan A., Casey Quinn, David M. Cate, Thomas H. Reilly, John Volckens, and Charles S. Henry. "Paper-based analytical devices for environmental analysis." Analyst 141, no. 6 (2016): 1874–87. http://dx.doi.org/10.1039/c5an02572a.

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Dissertations / Theses on the topic "Paper-based microfluidics"

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Terblanche, Johannes C. "Modified polysaccharide-based particles for strengthening paper." Thesis, Stellenbosch : University of Stellenbosch, 2010. http://hdl.handle.net/10019.1/5376.

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Thesis (PhD (Process Engineering))--University of Stellenbosch, 2010.<br>ENGLISH ABSTRACT: The ongoing trend in papermaking industries is to lower production costs by increasing the low cost filler content in the sheets. However, the disruption of inter-fibre bonding is accompanied by a deterioration of paper stiffness and mechanical properties if filler content exceeds 18 wt%. Polysaccharide solutions, such as starch, are often used as a low cost biodegradable additive to improve internal sheet strength when added to the wet-end of production. The amount of starch that can be added is however limited as only a small percentage will be retained in the paper web. A dual additive multifunctional polysaccharide system was developed to allow higher filler loading levels without detrimental deterioration in paper properties. In order to achieve a larger surface area for fibre/filler interaction and to reduce drainage losses, at least one of these additives was in particulate form. Anionic, cationic, and unsaturated derivatives were prepared using sodium monochloroacetate, 3-chloro-2-hydroxypropyltrimethylammonium chloride, and allyl bromide, respectively. The degree of substitution was determined by 1H-NMR spectroscopy and back titration methods and the interaction of the ionic modified derivatives with paper components was determined using fluorescence microscopy. Anionic modified polysaccharide particles were prepared using techniques such as macrogel ultrasonification, water-in-water emulsification, and in-situ cross-linking and carboxymethylation of granular starch. A process of adding sequential layers of oppositely charged polyelectrolyte layers onto the filler particles was also investigated. A novel approach of preparing modified particles with tailored size and distribution using microfluidics was studied and modelled using response surface methodology. Hand sheets were prepared using the dual additive system and improvements in stiffness, tear resistance, breaking length, and folding endurance were observed. The modified granular maize starch particles had a pre-eminent effect on improving stiffness at higher filler loadings (14% improvement at 30 wt% filler loading), while bulky particles prepared using microfluidics showed a more consistent improvement (between 6% and 10%) across the loading range. Overall improvements gained by the introduction of multi-layered soluble polymers onto fillers suggest that the introduction of nanotechnology to the papermaking process should be of potential benefit to the industry. Furthermore, the dual additive system developed during the course of this study should also be tested on a continuous pilot plant papermaking process.<br>AFRIKAANSE OPSOMMING: Die papierindustrie neig voortdurend daarna om produksiekostes te verlaag deur die persentasie lae koste vulstof wat gebruik word te verhoog. Aangesien die vulstof vesel kontak belemmer, gaan hoër vlakke (> 18 wt%) egter gepaard met ’n verlaging in papier styfheid en meganiese eienskappe. Polisakkaried oplossings, soos byvoorbeeld stysel, word dikwels gebruik as lae koste vergaanbare bymiddel om papier intern te versterk wanneer dit voor die vormingsproses bygevoeg word. Slegs ’n beperkte hoeveelheid stysel word egter behou in die papier matriks en oormatige oplossings ontsnap tydens dreinering in die afvalwater. ’n Dubbele multi-funksionele polisakkaried bymiddelsisteem was ontwikkel wat ongewensde verwakking in papiereienskappe verminder tydens vulstof verhogings. Ten minste een van die bymiddels was in partikelvorm om sodoende ’n groter oppervlak te bied vir vesel/vulstof interaksie en om dreineringsverliese te verminder. Anioniese, kationiese, sowel as onversadigde derivate was berei deur onderskeidelik gebruik te maak van natrium monochloroasetaat, 3-chloro-2-hidroksiepropieltrimetielammonium chloried, en alliel bromied. Die graad van substitutiese was bepaal met behulp van 1H-KMR spektroskopie sowel as titrasie tegnieke terwyl die ioniese interaksie van die gemodifiseerde stysels met die papierkomponente ondersoek was met behulp van fluoressensie mikroskopie. Anioniese polisakkaried partikels was berei met tegnieke soos makro-jel ultrasonifikasie, water-in-water emulsifikasie, en in-situ kruisbinding en karboksiemetielasie van stysel granulate. ’n Proses was ook ondersoek waar vulstof partikels omhul was in verskeie lae poliëlektroliet oplossings. ’n Nuwe benadering was toegepas waar gemodifiseerde partikels met voorafbepaalde grootte en verspreiding berei is deur gebruik te maak van mikrofluïdika en gemodelleer met behulp van oppervlakte ontwerp metodeleer. Papier toetse was uitgevoer met die bymiddelsisteem en algehele verbetering in styfheid, skeurweerstand, breeklengte, en voulydsaamheid is waargeneem. Die gemodifiseerde stysel granulate het die grootste verbetering in styfheid by hoë vulstofladings getoon (14% verbetering by 30 wt% vulstoflading) terwyl die groter mikrofluïdika-bereide partikels algehele verbetering (tussen 6% en 10%) getoon het oor die hele vulstoflading reeks. Die verbeteringe in styfheid sowel as meganiese eienskappe van papier voorberei met poliëlektroliet omhulde vulstof toon dat aanwending van nanotegnologie in hierdie bedryf potensieel voordelig kan wees. Opskalering van die polisakkaried bymiddels ontwikkel gedurende hierdie studie behoort uitgevoer te word vir verdere toetse op ’n kontinue papier loodsaanleg.
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Clayton, Katherine Noel. "Comparing Anti-VEGF Antibodies and Aptamers on Paper Microfluidic-Based Platforms." DigitalCommons@CalPoly, 2012. https://digitalcommons.calpoly.edu/theses/765.

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The field of microfluidics is expanding into what is known as paper microfluidics. This uses a paper platform rather than materials (i.e. PDMS, PMMA) that are commonly used in microfluidics research. Current devices require an expensive manufacturing process and external sources to power the device. Such devices are not practical in low resource environments. As a consequence, it is the goal of this Thesis to develop a three-dimensional, multiplexed assay chip using nitrocellulose membranes. This device comprises of multiple layers of nitrocellulose membranes with defined fluidic channels. The multiple layers are bound together using double backed tape, and imbedded between the layers are conjugate reagents. In the detection region both antibodies and aptamers were evaluated. The fiberglass pad where conjugate reagents would be contained, were initially saturated in dye. As sample was inputted into the three-dimensional chip, the fluid path could be visualized. Without the use of the conjugate pad the chip’s four detection regions showed detection within one minute of one another. However, the addition of this fibrous pad skewed time points dramatically. The hypothesis that a three-dimensional chip could be designed to detect different biomarkers in a multi-analyte sample was satisfied. However, simultaneous detection was only possible if the conjugate pad was either neglected or, possibly, a different material was used. Additionally, current lateral flow assay technologies, another research area that paper microfluidics spawns from, use antibodies in order to capture biomarkers in sample and provide visual signal to the user. However, antibodies are sensitive to denaturation with pH and temperature, whereas aptamers can withstand much more extreme environmental conditions. A two-dimensional nitrocellulose chip was designed to compare antibodies and aptamers as capture reagents to detect VEGF, using colloidal gold as a particle to visualize detection. Both monoclonal and polyclonal anti-VEGF antibodies were used and showed no signal. On the other hand, the anti-VEGF aptamer produced a visual signal when conjugated to biotin on its 5’ end. This data was further validated by a separate project analyzing the binding kinetics of the antibody and the aptamer using Surface Plasmon Resonance. Therefore, the hypothesis that aptamers could be used as a possible capture reagent in a paper microfluidic chip for the detection of VEGF was satisfied.
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Li, Hua. "Qualitative Blood Coagulation Test Using Paper-Based Microfluidic Lateral Flow Device." University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1406810864.

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Shen, Liuliu [Verfasser], J. M. Bastian [Akademischer Betreuer] Etzold, and Markus [Akademischer Betreuer] Biesalski. "Paper-based Microfluidics for Electrochemical Applications / Liuliu Shen ; J. M. Bastian Etzold, Markus Biesalski." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2020. http://d-nb.info/1211478149/34.

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Shen, Liuliu [Verfasser], J. M. Bastian Akademischer Betreuer] Etzold, and Markus [Akademischer Betreuer] [Biesalski. "Paper-based Microfluidics for Electrochemical Applications / Liuliu Shen ; J. M. Bastian Etzold, Markus Biesalski." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2020. http://nbn-resolving.de/urn:nbn:de:tuda-tuprints-117737.

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Ward, Jennifer Guerin. "Nitrocellulose Paper Based Microfluidic Platform Development and Surface Functionalization with Anti-IgE Aptamers." DigitalCommons@CalPoly, 2012. https://digitalcommons.calpoly.edu/theses/746.

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The purpose of this thesis project was to demonstrate the ability to utilize the capabilities of aptamers so that they may act as capture reagents for paper microfluidic devices. Several characterization experiments were conducted as a precursor before the final experimentation was performed. Paper characterization, manufacturing protocols for printing and heating, as well as 3D chip fabrication were all performed and analyzed. The results confirmed that the control of fluid through a 3D microfluidic device based in nitrocellulose is possible. For the biochemistry portion of this thesis report, antibodies and aptamers were chosen to react with IgE, an antibody that is present in high concentrations in the urine of patients diagnosed with respiratory distress. Antibody chips were successfully created as a baseline lateral flow assay for comparison to new aptamer detector reagents. The aptamer experiments were able to demonstrate that it is possible to utilize the capabilities of aptamers so that they may behave as capture reagents in paper microfluidic devices. Overall, the experiments performed were extremely supportive of the ability to develop the field of paper microfluidics with the use of aptamers so that patient populations across the globe can be more accurately and effectively diagnosed.
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Murdock, Richard C. "Development of Microfluidic Paper-based Analytical Devices for Point-of-Care Human Physiological and Performance Monitoring." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1439308025.

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Holler, Alicia Leanne. "Functional 3-D Cellulose and Nitrocellulose Paper-based, Microfluidic Device Utilizing ELISA Technology for the Detection/Distinction Between Hemorrhagic and Ischemic Strokes." DigitalCommons@CalPoly, 2016. https://digitalcommons.calpoly.edu/theses/1707.

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The purpose of this thesis project is to demonstrate and evaluate an enzyme-linked immunosorbent assay (ELISA) on a paper microfluidic device platform. The integration of ELISA technology onto paper microfluidic chips allows for a quantitative detection of stroke biomarkers, such as glial fibrillary acidic protein (GFAP). Dye experiments were performed to confirm fluid connectivity throughout the 3D chips. Several chip and housing designs were fabricated to determine an optimal design for the microfluidic device. Once this design was finalized, development time testing was performed. The results confirmed that the paper microfluidic device could successfully route fluid throughout its channels at a reasonable rate. For the biochemistry portion of this thesis project, antibodies were selected to target the intended stroke biomarker: GFAP. However, due to antibody pairing complications, the protein chosen for this project was natural human cardiac troponin T, which is elevated in the bloodstream of patients who have suffered a stroke. Several antibody experiments were performed to help finalize the procedure for performing an ELISA on the paper chip. The final antibody experiment was able to demonstrate that a paper microfluidic device utilizing ELISA techniques can successfully detect a stroke biomarker at physiologically relevant concentrations. Overall, this project supported the ability to accurately and effectively diagnose stroke in a timely manner through the use of a paper microfluidic device.
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Klasner, Scott A. "Novel capillary and microfluidic devices for biological analyses." Diss., Manhattan, Kan. : Kansas State University, 2010. http://hdl.handle.net/2097/3747.

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Glavan, Ana. "Chemical Approaches to the Surface Engineering of Paper and Cellulose-Based Materials for Microfluidics, Electronics and Low-Cost Diagnostics." Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:26718749.

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Paper (and other cellulose-based materials such as cotton thread and fabrics) are underexploited as materials for the construction of “high-tech” and “lab-on-a-chip” devices. One major drawback of paper is its tendency to absorb water from the environment and, with wetting, to change its mechanical properties; other challenges relate to control over the attachment of molecules (e.g. antibodies, DNA) and cells on its surface, and to the addition of electronic function. The goal of this thesis is to develop paper as a substrate for a range of applications— microfluidics, substrates for electronic systems and MEMS, low-cost diagnostics, cell biology, and optics. The approach involves chemically modifying the surface of the paper to provide new functions without altering any of its defining properties: mechanical flexibility, foldability, light weight, gas permeability, and low cost. The first part of my thesis describes the modification of paper by silanization with organosilanes such as alkyl- and fluoroalkyl trichlorosilanes in the gas phase. Here, silanization is used to lower the surface free energy of the paper and to minimize the tendency of paper to absorb liquids and vapors, and especially water. Chapter 1 and Appendix 3 demonstrate that the combination of long fluoroalkyl chains of grafted siloxanes with the micro-scale roughness and porosity of paper yielded a material that is omniphobic (both hydrophobic and oleophobic), while preserving the properties of mechanical flexibility and low resistance to transport of gas of the untreated paper. Appendix 3 shows that features of omniphobic paper can be used to construct microtiter plates and liquid-filled gas sensors using standard paper folding techniques, while Appendix 4 shows that new type of microfluidic device fabricated by carving microchannels into the surface of omniphobic paper. The resulting devices have open, unobstructed channels (with dimensions as small as 45 μm) and thus exhibit fluid dynamics similar to conventional PDMS-based microfluidics, but are much lighter and have the potential to be much less expensive than PDMS-based devices. The second part of my thesis is focused on engineering the surface of paper to enable efficient immobilization of capture and target molecules for bioanalysis. In one approach, described in Appendix 5, we exploit the ease with which the surface chemistry of paper (i.e. the surface of the cellulose fibers making up the paper) can be modified, in order to enhance the immobilization of antibodies and antigens on the surface of the paper via hydrophobic interactions, while preventing the wicking of the fluids into the paper substrate. As an application in low-cost diagnostics, we describe a low-cost electrochemical device for ELISA intended for use in resource-limited settings. In a second approach, described in Chapter 2, we developed of an efficient procedure for assembling microarrays of ssDNA and proteins on paper, at the lowest practical cost. This method starts with the synthesis of DNA oligonucleotides covalently linked to paper, and proceeds to generate ssDNA arrays that, through hybridization with complementary strands of DNA, are capable of simultaneously capturing DNA, DNA-conjugated protein antigens, and DNA-conjugated antibodies. The third part of my thesis describes the simple, inexpensive fabrication of electrodes for paper-based electrochemical systems. A first method describes, in Appendix 6, the development of inkjet printing as a method for high resolution printing of conductive patterns on omniphobic “RF” paper, both to extend its promise as a substrate for paper electronics, and to enable us to integrate it into our program in low-cost, paper based diagnostics. A second method, described in Chapter 3, circumvents the need for printing, and instead focuses on the fabrication and reconfiguration of simple, versatile, and inexpensive electroanalytical devices in which conventional stainless-steel pins—in unmodified form or after coating with a carbon paste—are used as electrodes.<br>Chemistry and Chemical Biology
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Book chapters on the topic "Paper-based microfluidics"

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Jafry, Ali Turab, Hosub Lim, and Jinkee Lee. "Basic Paper-Based Microfluidics/Electronics Theory." In Bioanalysis. Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-8723-8_2.

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Xue, Peng, and Yuejun Kang. "Paper-Based Sensors and Microfluidic Chips." In Encyclopedia of Microfluidics and Nanofluidics. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4614-5491-5_1712.

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Xue, Peng, and Yuejun Kang. "Paper-Based Sensors and Microfluidic Chips." In Encyclopedia of Microfluidics and Nanofluidics. Springer US, 2013. http://dx.doi.org/10.1007/978-3-642-27758-0_1712-4.

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Yamada, Kentaro, and Daniel Citterio. "Paper-Based Microfluidics for Point-of-Care Medical Diagnostics." In Bioanalysis. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-6229-3_13.

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Rashiku, Mohammed, and Shantanu Bhattacharya. "Fabrication Techniques for Paper-Based Microfluidic Devices." In Advanced Functional Materials and Sensors. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-15-0489-1_3.

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Jaitpal, Siddhant, and Debjani Paul. "Flow Control in Paper-Based Microfluidic Devices." In Advanced Functional Materials and Sensors. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-15-0489-1_4.

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Phillips, Scott T., and Nicole K. Thom. "Three-Dimensional, Paper-Based Microfluidic Devices Containing Internal Timers for Running Time-Based Diagnostic Assays." In Microfluidic Diagnostics. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-134-9_13.

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Pandey, Mohit, Mahima Srivastava, Krutika Shahare, and Shantanu Bhattacharya. "Paper Microfluidic-Based Devices for Infectious Disease Diagnostics." In Advanced Functional Materials and Sensors. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-15-0489-1_13.

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Kumar, Sanjay, Pulak Bhushan, and Shantanu Bhattacharya. "Fluid Transport Mechanisms in Paper-Based Microfluidic Devices." In Advanced Functional Materials and Sensors. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-15-0489-1_2.

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Saha, Anubhuti, and Shantanu Bhattacharya. "Paper Microfluidic Based Device for Blood/Plasma Separation." In Advanced Functional Materials and Sensors. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-15-0489-1_5.

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Conference papers on the topic "Paper-based microfluidics"

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Galanis, Panagiotis, Peijun He, Ioannis Katis, et al. "Laser-direct-writing to enable filtration in paper-based devices." In Microfluidics, BioMEMS, and Medical Microsystems XVII, edited by Bonnie L. Gray and Holger Becker. SPIE, 2019. http://dx.doi.org/10.1117/12.2508753.

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Choi, G., and S. Choi. "Bacterial cell transportation in paper-based microfluidics." In TRANSDUCERS 2015 - 2015 18th International Solid-State Sensors, Actuators and Microsystems Conference. IEEE, 2015. http://dx.doi.org/10.1109/transducers.2015.7181297.

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He, Peijun, Ioannis Katis, Catherine Bryant, et al. "Laser direct-write patterned paper-based devices for detection of bacterial pathogens (Conference Presentation)." In Microfluidics, BioMEMS, and Medical Microsystems XVII, edited by Bonnie L. Gray and Holger Becker. SPIE, 2019. http://dx.doi.org/10.1117/12.2506790.

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Nargang, Tobias Martin, Robert Dierkes, Julia Bruchmann, et al. "Structuring unbreakable and autoclavable hydrophobic barriers in paper via direct printing and mask-based photolithography." In Microfluidics, BioMEMS, and Medical Microsystems XVII, edited by Bonnie L. Gray and Holger Becker. SPIE, 2019. http://dx.doi.org/10.1117/12.2507385.

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Tirapu-Azpiroz, Jaione, Matheus Esteves Ferreira, Daniel Vitor Lopes Marcondes Marçal, Ademir Ferreira Silva, Ricardo Luis Ohta, and Mathias Bernhard Steiner. "High-resolution colorimetric detection on paper-based microfluidic devices via indicator merging and machine learning." In Microfluidics, BioMEMS, and Medical Microsystems XIX, edited by Bonnie L. Gray and Holger Becker. SPIE, 2021. http://dx.doi.org/10.1117/12.2577303.

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Nguyen, Nam-Trung. "Thermal Control for Droplet-Based Microfluidics." In 2008 Second International Conference on Integration and Commercialization of Micro and Nanosystems. ASMEDC, 2008. http://dx.doi.org/10.1115/micronano2008-70277.

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This paper presents our recent works on thermal control for droplet-based microfluidics. Temperature dependent properties of liquids have been use for actuation and many other applications in droplet-based microfluidics. In analogy to an analog/digital electronic circuits, a droplet-based microfluidic system consists for three main subsystems: droplet formation (analog/digital converter), droplet manipulation (digital processing) and droplet merging (digital/analog converter). This paper will present our recent achievements in thermal control of droplet formation in different configurations such as T-junction and cross junction with integrated microheaters. Furthermore, results on droplet switching will be presented. The droplet switch represent basic logic gate that can be used to construct a more complex droplet-based digital network. Thermocapillary actuation of microdroplets in one-dimensional and two-dimensional microfluidic platforms will be presented. Both numerical and experimental results will be presented in this paper.
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Jaitpal, Siddhant, Suhash Chavva, and Samuel Mabbott. "Towards point-of-care detection of microRNAs using paper-based microfluidics." In Optical Diagnostics and Sensing XXI: Toward Point-of-Care Diagnostics, edited by Gerard L. Coté. SPIE, 2021. http://dx.doi.org/10.1117/12.2589180.

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Grau, Gerd. "Low-cost fabrication of paper-based systems: Microfluidics, sensors, electronics and deployment." In 2017 IEEE 60th International Midwest Symposium on Circuits and Systems (MWSCAS). IEEE, 2017. http://dx.doi.org/10.1109/mwscas.2017.8052866.

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Zwanenburg, P., X. Li, and X. Y. Liu. "Magnetic valves with programmable timing capability for fluid control in paper-based microfluidics." In 2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS). IEEE, 2013. http://dx.doi.org/10.1109/memsys.2013.6474225.

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10

Tanev, Georgi, and Jan Madsen. "A correct-by-construction design and programming approach for open paper-based digital microfluidics." In 2017 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP). IEEE, 2017. http://dx.doi.org/10.1109/dtip.2017.7984476.

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