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1

Fu, Yinghua, Zhixin Zhang, Xiaoping Tang, and Jiangling Su. "A narrative review of papilla preservation techniques in clinical dentistry." Medicine 104, no. 3 (2025): e41033. https://doi.org/10.1097/md.0000000000041033.

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The interdental papilla is closely associated with oral health and dental aesthetics. Interproximal papilla is an essential component of pink aesthetics as well as an indispensable prerequisite for the health of oral tissues. The loss of papillary height not only considerably affects final esthetic results, but also brings a series of periodontal complications. The deficiency of papilla can be induced by iatrogenic factors, particularly the flap technique, which is usually employed in oral surgeries. Therefore, preservation of the interdental papilla must be a consideration of flap designs. To avoid papilla defects secondary to conventional flaps, papilla-preserving flap designs have been widely studied in clinical practice. With numerous papilla preservation techniques (PPTs) increasingly being employed, not only is the postoperative pink aesthetic better maintained, but the predictability of surgical outcomes has been significantly enhanced. However, there is a lack of adequate literature that provides a comprehensive overview of PPTs in the field of dentistry. This review summarizes the latest developments in papilla preservation flap designs in the field of oral surgery, with a particular emphasis on their indications, limitations, incision characteristics, and clinical benefits. This review may provide optimal protocols for the personalized treatment.
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International, Journal of Dental Science and Innovative Research (IJDSIR). "Minimally Invasive Therapies in Periodontitis - A Literature Review." International Journal of Dental Science and Innovative Research (IJDSIR) 8, no. 2 (2025): 54–64. https://doi.org/10.5281/zenodo.15209989.

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<strong>Abstract</strong> Minimally invasive surgical techniques (MIST) in periodontics have emerged as a transformative approach to managing periodontal diseases, prioritizing the preservation of soft tissue and enhancing patient comfort. This review article discusses key minimally invasive procedures including the Modified Papilla Preservation Technique (MPPT), Simplified Papilla Preservation Flap (SPPF), Tunnel Technique, Entire Papilla Preservation Technique (EPP) and Non incised Papillae Surgical Approach (NIPSA). Each technique is elaborated upon with recent studies that validate their effectiveness in improving clinical outcomes, reducing postoperative pain, and enhancing aesthetic results. The review highlights the advantages of MIST, such as faster healing rates and higher patient satisfaction, while also acknowledging the limitations regarding their applicability in complex cases. Overall, this article underscores the significance of MIST in contemporary periodontal therapy and suggests that ongoing research will further solidify their role as standard practices in periodontal treatment protocols.
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Jakubowska, Sylwia, and Bartłomiej Górski. "Minimally Invasive Surgical Techniques for Periodontal Regeneration: Preserving the Entire Papilla Without Dissection—A Narrative Review." Journal of Clinical Medicine 14, no. 12 (2025): 4117. https://doi.org/10.3390/jcm14124117.

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Background: The aim of the present narrative review is to synthesize the available scientific evidence on the minimally invasive surgical techniques for periodontal regeneration preserving the entire papilla without dissection. Surgical treatment of intrabony defects may result in compromising the integrity of the interdental tissues and subsequent papilla loss. Therefore, it is indicated to investigate the approaches avoiding papillary incision over the osseous defect, thus optimizing wound healing conditions. Methods: Authors performed a search of literature via electronic databases such as PubMed, Web of Science, Cochrane, and Scopus, and extended by manual searching with a stop date of February 2025. Based on inclusion criteria only randomized clinical trials (RCT), cohort studies, case–control studies, and case series were included, and 106 records were initially identified. Various aspects of described novel approaches preserving the entire papilla were finally discussed. Results: A total of 12 studies were evaluated. There is a significant lack of randomized controlled clinical trials on minimally invasive techniques without incision in the papilla. However, numerous modifications of existing techniques have emerged, mainly in the form of case series and case reports with short-term data. Among them, some authors stated that the entire papilla preservation approaches may facilitate early soft tissue healing, reduce papilla trauma and the risk of gingival recession, minimize procedure time, improve flap stability, and alleviate discomfort and side effects, while others reported similar outcomes to conventional approaches and emphasize the need for further comparative clinical trials. Conclusions: Preserving papilla integrity and the soft tissue profile is essential for minimizing complications, especially in the esthetic zone. Within the limitations of this narrative review, presented findings emphasize the effectiveness of entire papilla preservation techniques in preventing post-surgery tissue loss compared to conventional incisions and flaps. Randomized controlled trials with longer follow-up periods and larger sample sizes are necessary to validate the efficacy of these approaches in comparison to established papilla preservation techniques.
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Takei, H. H., T. J. Han, F. A. Carranza, E. B. Kenney, and V. Lekovic. "Flap Technique for Periodontal Bone Implants: Papilla Preservation Technique." Journal of Periodontology 56, no. 4 (1985): 204–10. http://dx.doi.org/10.1902/jop.1985.56.4.204.

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Kaur, Tejaswani, Dilip Naik, Ashita Uppoor, Sangeeta Umesh Nayak, and Pragya Atray. "Clinical and radiographic assessment of the efficacy of platform switched implant and papilla preservation flap design in minimizing crestal bone loss around single tooth implant: A 6-month follow-up Study." Journal of Orofacial Sciences 16, no. 2 (2024): 96–104. https://doi.org/10.4103/jofs.jofs_350_23.

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Introduction: A healthy quantity and quality of bone surrounding dental implants, particularly the crestal bone, is essential to their overall success. Crestal bone preservation should therefore be taken into account even before treatment planning for implant placement. Numerous methods to prevent the loss of crestal bone have been reported in the literature. Platform-switched implants are one among them. Aim: The aim of this study was to assess the efficacy of platform-switched implants and papilla preservation flap design in minimizing interproximal bone loss around single-tooth implants. Material and Methods: In this parallel design randomized controlled trial, a total of 21 patients with single implant site were taken and were randomly divided into three groups—Group A: Platform matched implants with conventional flap design, Group B: Platform switched implants with conventional flap design, and Group C: Platform switched implants with papilla preservation flap design. Clinical parameters (PI, GI, mPI, and mGI index) and radiographic analysis were done to evaluate the outcome of these three techniques. Results: The mean crestal bone loss in Group A patients was 1.292 ± 0.084 mm at 3 months and 1.804 ±.038 mm at 6 months. The mean crestal bone loss in Group B patients was 0.631 ± 0.092 mm at 3 months and 1.139 ± 0.080 mm at 6 months. The mean crestal bone loss in Group C patients was 0.327 ±.075 mm at 3 months and 0.544 ± 0.084 mm at 6 months. Conclusion: Results show that minimum crestal bone loss was seen in Group C, followed by Group B, and maximum bone loss was seen in Group A. Hence, one may conclude that a combination of both platform-switched implants and papilla preservation flap design seems best to limit bone loss, followed by platform-switched implants.
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Yash, Singh, Raj Sharma Akash, Sharma Deepanshu, Shalini M., Sahni Sakshi, and Shukla Kanchan. "Impact of different flap approaches on the outcome of dental implant surgeries – A review." Journal of Orofacial Rehabilitation 3, no. 3 (2023): 40–49. https://doi.org/10.5281/zenodo.10425733.

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<strong>ABSTRACT</strong> <strong>Objective:</strong> This paper reviews the impact of different flap approaches in dental implant surgeries, focusing on their influence on outcomes and the principles guiding their use. <strong>Background:</strong> Implant dentistry aims to restore aesthetics and functionality in edentulous patients through osseointegrated implants. Flap elevation during implant placement enhances visibility of landmarks but may lead to complications like morbidity, discomfort, and tissue loss. Various flap designs and principles are employed to address these challenges. <strong>Methods:</strong> The review analyzes diverse flap designs, principles, and their implications in implant dentistry, emphasizing their impact on esthetics, bone preservation, and surgical outcomes. <strong>Results:</strong> Different flap approaches like flapless, vestibular incision, papilla sparing, and others are assessed in terms of their advantages, limitations, and impact on soft tissue aesthetics, bone resorption, and surgical success. Principles guiding flap design and management for esthetic implant therapy are also outlined. <strong>Conclusion:</strong> Preserving inter-dental papilla through appropriate flap designs is crucial in preventing bone denudation and subsequent resorption post-implant placement. Adhering to principles and employing suitable techniques ensures consistent and favorable esthetic outcomes in dental implant surgeries. <strong>Application:</strong> This review highlights the significance of flap approaches in implant dentistry, offering insights into optimizing surgical techniques and promoting patient-centered outcomes, contributing to enhanced esthetic and functional restoration. <strong>&nbsp;</strong> <strong>Keywords: </strong>Bone density, flaps, implant<strong> </strong>surgery, implants, surgical techniques.
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Rodriguez, Amanda, Diego Velasquez, and Hsun-Liang Chan. "Review of Intraoral Vasculature and Implications on Incision Designs of Periodontal and Implant Surgeries." International Journal of Periodontics & Restorative Dentistry 43, no. 6 (2023): 753–61. http://dx.doi.org/10.11607/prd.6213.

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Currently, the incision design for periodontal and implant surgeries is mainly based on the surgeon’s personal preference. The primary aim of this study is to review the intricate periodontal microvascular system and to illustrate the potential impact of commonly applied flap designs on the integrity of this system. A complete literature electronic search resulted in 37 relevant articles. The maxillary, facial, and lingual arteries supply the microvasculature system, including the supraperiosteal, intraligamental, and intraosseous arterioles. These arterioles have their own territories yet are extensively interconnected. The impact of common papilla management techniques are discussed, including tunneling; papilla base, incision, and preservation; and flap-releasing incisions. Flap design can impact reperfusion and blood inflow in the early healing phase, which eventually influences wound closure probability, healing speed, surgical predictability, tissue volume change, and postoperative morbidity. Future studies on the three-dimensional distribution of microvasculature and clinical impact of various flap designs on tissue reperfusion can lead to evidence-based incision selection and improved wound-healing outcomes.
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Stilidi, I. S., P. P. Arkhiri, I. A. Fainshtein, et al. "Pancreas-sparing duodenectomy with preservation of peripapillary part of duodenal wall: a new option of surgical treatment for duodenal tumor lesions." Pelvic Surgery and Oncology 12, no. 3 (2022): 11–18. http://dx.doi.org/10.17650/2686-9594-2022-12-3-11-18.

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Currently, with duodenal tumor lesion (duodenum), the possibility of performing economical operations that significantly improve the immediate results and quality of life of patients is increasingly being considered as an alternative to gastropancreatoduodenal resection. using the example of clinical observation, the article presents a new type of economical surgical intervention – duodenectomy with preservation of the peripapillary flap. The operation was performed in a patient with cancer of the resected stomach with a low spread of the tumor along the wall of the duodenum. At the control examination 9 months after the operation, the patient’s condition is satisfactory, without signs of impaired biliodynamics and passage of food through the intestinal tube. The proposed method differs from the existing prototype (papilloservative duodenectomy) by preserving the peripapillary flap of the duodenal wall.The insertion into the jejunum of not the fater papilla, but the surrounding wall of the duodenum eliminates its deformation and violation of patency and provides greater reliability of the formed suture, and the preservation of the small duodenal papilla with an additional pancreatic duct of Santorini can help reduce the frequency of postoperative pancreatitis and pancreonecrosis. In addition to cases of low lesions of the duodenum in gastric cancer, the method can be used in patients with non-epithelial and neuroendocrine tumors, as well as in secondary tumor invasion of the duodenum from the outside. The criterion limiting the performance of this type of operation is the distance from the edge of the tumor to the fater papilla less than 2.0–2.5 cm.Duodenectomy with preservation of the peripapillary flap can be considered as a way to improve the safety and quality of life in the surgical treatment of patients with a tumor lesion of the duodenum.
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Kuswandani, Sandra O. "Gingivectomy and flap operation procedure with papilla preservation technique in pyogenic granuloma patient." Journal of Dentomaxillofacial Science 3, no. 3 (2018): 180. http://dx.doi.org/10.15562/jdmfs.v3i3.740.

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Taschieri, Silvio, Massimo Del Fabbro, Luca Francetti, Isabella Perondi, and Stefano Corbella. "Does the Papilla Preservation Flap Technique Induce Soft Tissue Modifications over Time in Endodontic Surgery Procedures?" Journal of Endodontics 42, no. 8 (2016): 1191–95. http://dx.doi.org/10.1016/j.joen.2016.05.003.

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Petrovski, Mihajlo, and Kiro Papakoca. "SURGICAL MANIPULATION OF SOFT AND BONE TISSUE IN CONTEMPORARY DENTAL IMPLANTOLOGY." KNOWLEDGE - International Journal 54, no. 4 (2022): 639–43. http://dx.doi.org/10.35120/kij5404639p.

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Adequate and correct manipulation of soft and bone tissues during implant therapy is extremelyimportant. Knowledge of the biological, histological and of course the surgical characteristics of the tissues canlargely be a predictor of the correct implant prosthetic rehabilitation. The main aim of this research was to describeall aspects of surgical manipulation of the soft and bone tissues during the dental implantology procedures. We havemade adequate literature research for articles relevant to our topic-surgical manipulation of the soft and hard tissuesduring the dental implantology procedures published in the last two decades (2001-2021). Kew words used for theresearch were: “surgical manipulation”, “dental implantology”, “soft tissues”, “bone tissues” and their combination.Each implantologist should take into account the biological limitations of each patient, as well as the technicallimitations that may occur during the treatment. Oral soft tissues can be affected during the various stages of theimplant treatment. During the planning of a surgical intervention such as the placement of an implant, regardless ofwhether it is an immediate or a delayed loading implant, it is necessary to have an adequate manipulation of thesurrounding soft tissue and bone structures. When designing the flap should be taken into account the degree ofaccessibility required to access the bone, as well as the final position of the flap. It is also of great importance to takeinto account the preservation of good blood supply to the flap. Based on the exposure of bone after elevation, flapscan be classified as either full-thickness or mucoperiosteal flaps and partial-thickness or mucosal flaps. Dependingon how the interdental papilla will be treated, the incisions can either divide the papilla (conventional incision) orpreserve it (papilla-preserving incision). Based on the placement of flaps after surgery, they can be classified as: 1)nondisplaced flaps, where the flap is returned and sutured to its original position, or 2) displaced flaps, which areplaced apically, coronally, or laterally from their original position. The work in bone is quite complex and requiresknowledge of its morphological and histological characteristics. When working on bone, and especially whenplacing dental implants, it is necessary to note that it is necessary to enable constant cooling. The improvement ofold techniques and the development of new technologies have created a revolution in oral implantology, and now atherapist has numerous therapeutic options that can be incorporated into daily practice to facilitate the surgicalapproach itself. Hard-tissue and soft-tissue dental lasers, which are constantly improving and have a wide range ofindications, are becoming a part of everyday dental practice and also show significant advantages compared toconventional instruments and techniques when placing dental implants. Therefore, over time they will become aninvaluable and irreplaceable tool in modern dental implantology. After the performed extensive and deductiveliterature review, it can be concluded that from particular importance is the correct manipulation of soft and bonetissues during dental implantation. After tooth extraction, the placement of dental implants is largely determined bythe integrity of existing hard and soft tissues, such as the aesthetic outcome from the prosthodontic suprastructureover dental implants. Careful assessment of soft and bone tissue loss during implantation is paramount to the successof aesthetic implant procedures
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Rajendran, Poornima, Subraya Bhat, and Meena Anand. "Semilunar papilla preservation flap technique in combination with chorion membrane for pocket reduction and gingival recession coverage." Contemporary Clinical Dentistry 11, no. 2 (2020): 190. http://dx.doi.org/10.4103/ccd.ccd_354_19.

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Taschieri, Silvio, Stefano Corbella, and Massimo Del Fabbro. "Do Gingival Soft Tissues Benefit From the Application of a Papilla Preservation Flap Technique in Endodontic Surgery?" Journal of Oral and Maxillofacial Surgery 72, no. 10 (2014): 1898–908. http://dx.doi.org/10.1016/j.joms.2014.05.011.

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Cortellini, Pierpaolo, Maurizio S. Tonetti, Niklaus P. Lang, et al. "The Simplified Papilla Preservation Flap in the Regenerative Treatment of Deep Intrabony Defects: Clinical Outcomes and Postoperative Morbidity." Journal of Periodontology 72, no. 12 (2001): 1702–12. http://dx.doi.org/10.1902/jop.2001.72.12.1702.

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Anirudhan, Subha, G. Joy Shoba, Kavimalar Ravichandran, and Minu Koshy. "Successful Surgical Management of Periapical Cyst with Accidentally Extruded MTA through Open Apex - A Case Report with One Year Follow up." Journal of Interdisciplinary Dentistry 13, no. 3 (2023): 177–81. http://dx.doi.org/10.4103/jid.jid_28_23.

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ABSTRACT An immature tooth with a blunderbuss canal presents a challenge in achieving a hermetic seal. Closure of the wide-open apex with materials such as mineral trioxide aggregate (MTA), biodentine, and endosequence root repair material is required to achieve success. Despite following proper methods, the extrusion of filling material into the periapical region is unavoidable. In this case report, due to a lack of apical stop, MTA was extruded unintentionally. Endodontic surgery was performed to remove the extruded MTA and curettage of the apical lesion was done to remove the cystic lining. Follow-up after regular intervals of 1, 3, 6 months, and 1 year showed resolution of periapical radiolucency with radiopaque corticated borders surrounding the radiolucency. This case report describes the successful surgical management of accidentally extruded MTA through large wide-open apex. CLINICAL RELEVANCE TO INTERDISCIPLINARY DENTISTRY Surgical planning involved flap design in collaboration with periodontist for preservation of the interdental papilla.
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Di Tullio, Marcella, Beatrice Femminella, Andrea Pilloni, et al. "Treatment of Supra-Alveolar-Type Defects by a Simplified Papilla Preservation Technique for Access Flap Surgery With or Without Enamel Matrix Proteins." Journal of Periodontology 84, no. 8 (2013): 1100–1110. http://dx.doi.org/10.1902/jop.2012.120075.

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Retzepi, M., M. Tonetti, and N. Donos. "Comparison of gingival blood flow during healing of simplified papilla preservation and modified Widman flap surgery: a clinical trial using laser Doppler flowmetry." Journal of Clinical Periodontology 34, no. 10 (2007): 903–11. http://dx.doi.org/10.1111/j.1600-051x.2007.01119.x.

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Deo, Vikas, Ashok Bhati, and Tony Kurien. "The Pouch and Tunnel Technique for the Management of Adjacent Gingival Recession Defects: Surgical Correction and One-Year Follow-Up." Journal of Contemporary Dental Practice 11, no. 5 (2010): 41–48. http://dx.doi.org/10.5005/jcdp-11-5-41.

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Abstract Aim The aim of this report is to present a minimally invasive periodontal plastic surgical method for the treatment of gingival augmentation coronal to area of recession on the facial aspect of the mandibular central incisors. Background Gingival recession is a relatively common condition patients may discuss with their general dental practitioner. Several improvements in the available corrective surgical techniques have evolved, especially in flap design of periodontal cosmetic surgeries, which can produce a favorable final treatment outcome. Case Description A 21-year-old male patient diagnosed with Miller class II marginal tissue recession on the facial surface of the mandibular right and left central incisors was treated with a subepithelial connective tissue autograft underneath a supraperiosteal pouch and tunnel recipient site for multiple areas of gingival recession This flap design allowed intimate contact of donor tissue to the recipient site. One-year follow-up examination of the surgical site revealed excellent and stable root surface coverage. Summary The use of a technique that involves preservation of papilla height and ensures maximum blood supply to the graft helps to attain excellent esthetic and functional long-term results. Clinical Significance Given the increasing patient concerns about dental esthetics, the surgical treatment modality presented can be beneficial in efforts to meet the esthetic and functional demands of patients, thereby contributing positively to treatment acceptance and the overall outcome. Citation Kurien T, Deo V, Bhati A. The pouch and tunnel technique for the management of adjacent gingival recession defects: Surgical correction and one-year follow-up. J Contemp Dent Pract [Internet]. 2010 October; 11(5):041- 048. Available from: http://www.thejcdp.com/ journal/view/volume11-issue5-deo
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Pukas, K. V., and V. V. Lazoryshynets. "The valve-preserving operations on a chordo-papillary continuum in a mitral valve prosthesis." Klinicheskaia khirurgiia 87, no. 1-2 (2020): 8–10. http://dx.doi.org/10.26779/2522-1396.2020.1-2.08.

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Objective. Studying of morphometric indices and contractility of left ventricle in various variants of preservation of chordo-papillary continuum in late period after the mitral valve prosthesis.&#x0D; Materials and methods. Analysis in 634 patients with isolated mitral valve failure, who were surgically treated from Sept. 1 2005 till Jan. 1 2007, was conducted. While the mitral valve prosthesis the chordo-papillary continuum was conducted, using preservation of the mitral valve posterior flap (41 patients) and simultaneous translocations of chordo-papillary muscles of anterior flap and preservation of posterior flap of a mitral valve (57 patients).&#x0D; Results. While comparing morphometric indices of left ventricle in left ventriculomegaly on a hospital stage and in late postoperative period when complete excision of a mitral valve in its prosthesis was performed, and when posterior flap was preserved, and simultaneously the posterior and anterior mitral valve flaps the improvement of the indices was observed, as well as normalization of a contractile function of left ventricle if a subvalvular space is preserved.&#x0D; Conclusion. Preservation of chordo-papillary continuum while performing the mitral valve prosthesis improves morphometric indices and contractility of left ventricle on a hospital stage and in late follow-up period.
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Guarnieri, Renzo. "Long-Term (15 to 20 Years) Outcomes of Papillae Preservation Flap Surgery in Esthetic Areas." International Journal of Periodontics & Restorative Dentistry 39, no. 3 (2019): 349–59. http://dx.doi.org/10.11607/prd.4017.

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Bolshak, A. A., V. Zh Boukarim, K. E. Vakulenko, et al. "Preservation of the left ventricle contractility while performing of the combined mitral-aortal failure correction." Klinicheskaia khirurgiia 87, no. 11-12 (2020): 10–14. http://dx.doi.org/10.26779/2522-1396.2020.11-12.10.

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Objective. The studying of possibilities of procedures, directed on preservation of left ventricle while doing a mitral valve prosthesis in operative correction of combined mitral-aortal failure.&#x0D; Materials and methods. In the analysis the results of surgical treatment of 340 patients, suffering combined mitral-aortal failure and a left-sided ventriculomegaly, who were operated in N. M. Amosov National Institute of Cardio-Vascular Surgery NAMS of Ukraine, were included. In all the patients a mitral valve prosthesis in combination with the aortal failure correction (prosthesis) was performed. In 83 patients the mitral valve prosthesis with complete preservation of posterior flap (Group A) was conducted, in 97 - with translocation of chords with papillar muscles of anterior flap in combination with posterior flap (Group B), in 160 - without preservation of the undervalvular apparatus (Group C). Definitely-systolic index of left ventricle in Groups A, B and C have constituted (87.4 ± 10.5), (88.4 ± 11.1) and (89.4 ± 11.5) ml/m2 accordingly; left ventricular ejection fraction have constituted 0.51 ± 0.03, 0.5 ± 0.03 and 0.51 ± 0.03 accordingly.&#x0D; Results. In Group A on a hospital stage 2 (2.5%) patients died, in Group B - 2 (2.1%) patients, and in Group C - 5 (3.1%). Definitely-systolic index of left ventricle on the tenth-eleventh postoperative day in Groups A, B and C have constituted (74.3 ± 9.8), (69.4 ± 8.2) and (76.4 ± 9.2) ml/m2 accordingly, while in late follow-up period - (55.4 ± 8.4), (49.4 ± 7.2) and (62.4 ± 7.2) ml/m2 accordingly. The left ventricle ejection fraction on the tenth-eleventh postoperative day in Groups A, B and C have constituted 0.54 ± 0.03, 0.55 ± 0.03 and 0.53 ± 0.03 accordingly, and in late follow-up period - 0.55 ± 0.03, 0.57 ± 0.03 and 0.54 ± 0.03 accordingly.&#x0D; Conclusion. In the left-sided ventriculomegaly and combined mitral-aortal failure the a maximal preservation of undervalvular structures of mitral valve, while its prosthesis performance, constitutes a serious component, which leads to improvement of morphometric indices of left ventricle on hospital stage and in follow-up period as well.
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Linares, Antonio, Pierpaolo Cortellini, Niklaus P. Lang, Jean Suvan, and Maurizio S. Tonetti. "Guided tissue regeneration/deproteinized bovine bone mineral or papilla preservation flaps alone for treatment of intrabony defects. II: radiographic predictors and outcomes." Journal of Clinical Periodontology 33, no. 5 (2006): 351–58. http://dx.doi.org/10.1111/j.1600-051x.2006.00911.x.

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Cortellini, Pierpaolo, Simone Cortellini, and Maurizio S. Tonetti. "Papilla preservation flaps for periodontal regeneration of molars severely compromised by combined furcation and intrabony defects: Retrospective analysis of a registry‐based cohort." Journal of Periodontology 91, no. 2 (2019): 165–73. http://dx.doi.org/10.1002/jper.19-0010.

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Rokn, A., SH Bassir, AA Rasouli Ghahroudi, MJ Kharazifard, and R. Manesheof. "Long-term Stability of Soft Tissue Esthetic Outcomes Following Conventional Single Implant Treatment in the Anterior Maxilla: 10-12 Year Results." Open Dentistry Journal 10, no. 1 (2016): 602–9. http://dx.doi.org/10.2174/1874210601610010602.

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Purpose: The present study aimed to evaluate the long-term stability of esthetic outcomes of soft tissue around maxillary anterior single-tooth implants after 10-to-12 years of loading. Methods: Patients who had been treated for single-tooth implants in the anterior maxilla between February 2000 and July 2002 were invited to participate in the study. All implants had been placed according to delayed implant placement and conventional loading protocols without any connective tissue graft or papilla preservation flaps. Pink Esthetic Score (PES) was rated using standardized clinical photographs to assess the esthetic outcomes of the implant treatment at the time of crown placement and at time of follow-up examination which was at least 10 years after the crown placement. Results: A total of 19 patients were included. The mean score of PES was 11.63 (SD 1.61; range 7-14) at baseline. After 10-to-12 years of function, a mean PES score of 11.05 (SD 2.09; range 6–14) was recorded. No significant differences were found in the esthetic outcomes, categorized based on clinically relevant levels, between the baseline and follow-up session (p&gt;0.05). Conclusion: Within limitation of the present study, it can be concluded that the esthetic outcomes of soft tissue around the maxillary anterior single-tooth implants placed using conventional implant placement technique remained stable in the long-term.
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Poinar, Jr., George O., and Kenton L. Chambers. "Cyathitepala papillosa gen. et sp. nov., a mid-Cretaceous fossil flower from Myanmar amber with valvate anthers." Journal of the Botanical Research Institute of Texas 14, no. 2 (2020): 351–58. http://dx.doi.org/10.17348/jbrit.v14.i2.1013.

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Although partially damaged prior to its preservation in coniferous resin, the flower of Cyathitepala papillosa retains enough morphological features to justify its description as a new genus and species of fossil angiosperms. The perianth is incomplete, but there are at least 6 large outer tepals and numerous smaller, spirally arranged inner ones. The limbs of some of the larger tepals are cup-shaped and face abaxially, while the smaller inner tepals are flat or have adaxially folded margins. There is an inner series of erect, apically truncate tepals surrounding the stamens. The surfaces and margins of the tepals are densely papillate. There is a whorl of ca. 12 stamens with anthers that dehisce by two dorsally hinged valves. Nothing remains of the receptacle or pedicel of the flower, but the superior portion of the pistil is conic and bears two columnar, erect styles. The fossil is compared with three previously described fossil genera, Setitheca, Zygadelphus, and Strombothelya, which were suggested as having a possible relationship with certain families of order Laurales.
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Rojas, Mariana A., Lorenzo Marini, Paola Russo, Vittorio Blardi, Patrick R. Schmidlin, and Andrea Pilloni. "Clinical Pilot Series of Non-Self-Contained Periodontal Infrabony Defects Treated with a Slowly Resorbable Bovine Pericardium Membrane in Combination with Low-Temperature-Treated Decellularized Bovine Bone Particles." Dentistry Journal 9, no. 10 (2021): 110. http://dx.doi.org/10.3390/dj9100110.

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The aim of this case series was to present the clinical outcomes of non-contained intrabony periodontal defects (IPDs) treated by means of papillary preservation flaps in association with a slowly resorbable bovine pericardium membrane (BPM) and a low-temperature-treated bovine bone graft (BBG). Eight healthy, non-smoking patients (two males and six females, mean age 48 ± 8 years) with stage 3 periodontitis and at least one site with residual probing depth (PD) ≥ 6 mm associated with a non-contained IPD ≥ 3 mm were treated. Two weeks after surgery, no adverse events were observed, and an early wound healing score (EHS) of 8.1 ± 1.0 was recorded. After 1 year, the mean probing depth (PD) reduction and mean clinical attachment level gain (CAL-gain) accounted for 4.8 ± 0.7 and 3.5 ± 0.7 mm, respectively, whereas the mean gingival recession (REC) was of 1.2 ± 0.3 mm. Radiographic bone fill was observed in all cases. In conclusion, the treatment of non-contained IPDs with a slowly resorbable BPM and a low-temperature-treated BBG could be considered safe and may result in significant clinical improvements 1 year after surgery.
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27

Fayez, R., A. AlMuntashery, G. Bodie, et al. "Canadian Surgery Forum1 Is laparoscopic sleeve gastrectomy a reasonable stand-alone procedure for super morbidly obese patients?2 Postoperative monitoring requirements of patients with obstructive sleep apnea undergoing bariatric surgery3 Role of relaparoscopy in the diagnosis and treatment of bariatric complications in the early postoperative period4 Changes of active and total ghrelin, GLP-1 and PYY following restrictive bariatric surgery and their impact on satiety: comparison of sleeve gastrectomy and adjustable gastric banding5 Prioritization and willingness to pay for bariatric surgery: the patient perspective6 Ventral hernia at the time of laparoscopic gastric bypass surgery: Should it be repaired?7 Linear stapled gastrojejunostomy with transverse handsewn enterotomy closure significantly reduces strictures for laparoscopic Roux-en-Y bypass8 Laparoscopic biliopancreatic diversion with duodenal switch as second stage for super super morbidly obese patients. Do all patients benefit?9 Sleeve gastrectomy in the super super morbidly obese (BMI > 60 kg/m2): a Canadian experience10 Laparoscopic gastric bypass for the treatment of refractory idiopathic gastroparesis: a report of 2 cases11 Duodeno-ileal switch as a primary bariatric and metabolic surgical option for the severely obese patient with comorbidities: review of a single-institution case series of duodeno-ileal intestinal bypass12 Management of large paraesophageal hernias in morbidly obese patients with laparoscopic sleeve gastrectomy: a case series13 Early results of the Ontario bariatric surgical program: using the bariatric registry14 Improving access to bariatric surgical care: Is universal health care the answer?15 Early and liberal postoperative exploration can reduce morbidity and mortality in patients undergoing bariatric surgery16 Withdrawn17 Identification and assessment of technical errors in laparoscopic Roux-en-Y gastric bypass18 A valid and reliable tool for assessment of surgical skill in laparoscopic Roux-en-Y gastric bypass19 Psychiatric predictors of presurgery drop-out following suitability assessment for bariatric surgery20 Predictors of outcomes following Roux-en-Y gastric bypass surgery at The Ottawa Hospital21 Prophylactic management of cholelithiasis in bariatric patients: Is routine cholecystectomy warranted?22 Early outcomes of Roux-en-Y gastric bypass in a publicly funded obesity program23 Similar incidence of gastrojejunal anastomotic stricture formation with hand-sewn and 21 mm circular stapler techniques during Roux-en-Y gastric bypass24 (CAGS Basic Science Award) Exogenous glucagon-like peptide-1 improves clinical, morphological and histological outcomes of intestinal adaptation in a distal-intestinal resection piglet model of short bowel syndrome25 (CAGS Clinical Research Award) Development and validation of a comprehensive curriculum to teach an advanced minimally invasive procedure: a randomized controlled trial26 Negative-pressure wound therapy (iVAC) on closed, high-risk incisions following abdominal wall reconstruction27 The impact of seed granting on research in the University of British Columbia Department of Surgery28 Quality of surgical care is inadequate for elderly patients29 Recurrence of inguinal hernia in general and hernia specialty hospitals in Ontario, Canada30 Oncostatin M receptor deficiency results in increased mortality in an intestinal ischemia reperfusion model in mice31 Laparoscopic repair of large paraesophageal hernias with anterior gastropexy: a multicentre trial32 Response to preoperative medical therapy predicts success of laparoscopic splenectomy for immune thrombocytopenic purpura33 Perioperative sepsis, but not hemorrhagic shock, promotes the development of cancer metastases in a murine model34 Measuring the impact of implementing an acute care surgery service on the management of acute biliary disease35 Patient flow and efficiency in an acute care surgery service36 The relationship between treatment factors and postoperative complications after radical surgery for rectal cancer37 Risk of ventral hernia after laparoscopic colon surgery38 Urinary metabolomics as a tool for early detection of Barrett’s and esophageal cancer39 Construct validity of individual and summary performance metrics associated with a computer-based laparo-scopic simulator40 Impact of a city-wide health system reorganization on emergency department visits in hospitals in surrounding communities41 Transcatheter aortic valve implantation for the nonoperative management of aortic stenosis: a cost-effectiveness analysis42 Breast cancer: racial differences in age of onset. A potential confounder in Canadian screening recommendations43 Risk taking in surgery: in and out of the comfort zone44 A tumour board in the office: Track those cancer patients!45 Increased patient BMI is not associated with advanced colon cancer stage or grade on presentation: a retrospective chart review46 Consensus statements regarding the multidisciplinary care of limb amputation patients in disasters or humanitarian emergencies. Report of the 2011 Humanitarian Action Summit Surgical Working Group on amputations following disasters or conflict47 Learning the CanMEDS role of professional: a pilot project of supervised discussion groups addressing the hidden curriculum48 Assessing the changing scope of training in Canadian general surgery programs: expected versus actual experience49 Predicting need for surgical management for massive gastrointestinal hemorrhage50 International health care experience: using CanMEDS to evaluate learning outcomes following a surgical mission in Mampong, Ghana51 The open abdomen: risk factors for mortality and rates of closure52 How surgeons think: an exploration of mental practice in surgical preparation53 The surgery wiki: a novel method for delivery of under-graduate surgical education54 Understanding surgical residents’ postoperative practices before implementing an enhanced recovery after surgery (ERAS) guideline at the University of Toronto55 From laparoscopic transabdominal to posterior retroperitoneal adrenalectomy: a paradigm shift in operative approach56 A retrospective audit of outcomes in patients over the age of 80 undergoing acute care abdominal surgery57 Canadian general surgery residents’ perspectives on work-hour regulations58 Timing of surgical intervention and its outcomes in acute appendicitis59 Preparing surgical trainees to deal with adverse events. An outline of learning issues60 Acute care surgical service: surgeon agreement at the time of handover61 Predicting discharge of elderly patients to prehospitalization residence following emergency general surgery62 Morbidity and mortality after emergency abdominal surgery in octo- and nonagenarians63 The impact of acute abdominal illness and urgent admission to hospital on the living situation of elderly patients64 A comparison of laparoscopic versus open subtotal gastrectomy for antral gastric adenocarcinoma: a North American perspective65 Minimally invasive excision of ectopic mediastinal parathyroid adenomas66 Perioperative outcomes of laparoscopic hernia repair in a tertiary care centre: a single institution’s experience67 Evaluation of a student-run, practical and didactic curriculum for preclerkship medical students68 Joseph Lister: Father of Modern Surgery69 Comparisons of melanoma sentinel lymph node biopsy prediction nomograms in a cohort of Canadian patients70 Local experience with myocutaneous flaps after extensive pelvic surgery71 The treatment of noncirrhotic splanchnic vein thrombosis: Is anticoagulation enough?72 Implementation of an acute care surgery service does not affect wait-times for elective cancer surgeries: an institutional experience73 Use of human collagen mesh for closure of a large abdominal wall defect, after colon cancer surgery, a case report74 The role of miR-200b in pulmonary hypoplasia associated with congenital diaphragmatic hernia75 Systematic review and meta-analysis of electrocautery versus scalpel for incising epidermis and dermis76 Accuracy of sentinel lymph node biopsy for early breast cancer in the community setting in St. John’s, New-foundland: results of a retrospective review77 Acute surgical outcomes in the 80 plus population78 The liberal use of platelets transfusions in the acute phase of trauma resuscitation: a systematic review79 Implementation of an acute care surgical on call program in a Canadian community hospital80 Short-term outcomes following paraesophageal hernia repair in the elderly patient81 First experience with single incision surgery: feasibility in the pediatric population and cost evaluation82 The impact of the establishment of an acute care surgery unit on the outcomes of appendectomies and cholecystectomies83 Description and preliminary evaluation of a low-cost simulator for training and evaluation of flexible endoscopic skills84 Tumour lysis syndrome in metastatic colon cancer: a case report85 Acute care surgery service model implementation study at a single institution86 Colonic disasters approached by emergent subtotal and total colectomy: lessons learned from 120 consecutive cases87 Acellular collagen matrix stent to protect bowel anastomoses88 Lessons we learned from preoperative MRI-guided wire localization of breast lesions: the University Health Network (UHN) experience89 Interim cost comparison for the use of platinum micro-coils in the operative localization of small peripheral lung nodules90 Routine barium esophagram has minimal impact on the postoperative management of patients undergoing esophagectomy for esophageal cancer91 Iron deficiency anemia is a common presenting issue with giant paraesophageal hernia and resolves following repair92 A randomized comparison of different ventilation strategies during thoracotomy and lung resection93 The Canadian Lung Volume Reduction Surgery study: an 8-year follow-up94 A comparison of minimally invasive versus open Ivor-Lewis esophagectomy95 A new paradigm in the follow-up after curative resection for lung cancer: minimal-dose CT scan allows for early detection of asymptomatic cancer activity96 Predictors of lymph node metastasis in early esophageal adenocarcinoma: Is endoscopic resection worth the risk?97 How well can thoracic surgery residents operate? Comparing resident and program director opinions98 The impact of extremes of age on short- and long-term outcomes following surgical resection of esophageal malignancy99 Epidermal growth factor receptor targeted gold nanoparticles for the enhanced radiation treatment of non–small cell lung cancer100 Laparoscopic Heller myotomy results in excellent outcomes in all subtypes of achalasia as defined by the Chicago classification101 Neoadjuvant chemoradiation versus surgery in managing esophageal cancer102 Quality of life postesophagectomy for cancer!103 The implementation, evolution and translocation of standardized clinical pathways can improve perioperative outcomes following surgical treatment of esophageal cancer104 A tissue-mimicking phantom for applications in thoracic surgical simulation105 Sublobar resection compared with lobectomy for early stage non–small cell lung cancer: a single institution study106 Not all reviews are equal: the quality of systematic reviews and meta-analyses in thoracic surgery107 Do postoperative complications affect health-related quality of life after video-assisted thoracoscopic lobectomy for patients with lung cancer? A cohort study108 Thoracoscopic plication for palliation of dyspnea secondary to unilateral diaphragmatic paralysis: A worthwhile venture?109 Thoracic surgery experience in Canadian general surgery residency programs110 Perioperative morbidity and pathologic response rates following neoadjuvant chemotherapy and chemoradiation for locally advanced esophageal carcinoma111 An enhanced recovery pathway reduces length of stay after esophagectomy112 Predictors of dysplastic and neoplastic progression of Barrett’s esophagus113 Recurrent esophageal cancer complicated by tracheoesophageal fistula: management by means of palliative airway stenting114 Pancreaticopleural fistula-induced empyema thoracis: principles and results of surgical management115 Prognostic factors of early postoperative mortality following right extended hepatectomy116 Optimizing steatotic livers for transplantation using a cell-penetrating peptide CPP-fused heme oxygenase117 Video outlining the technical steps for a robot-assisted laparoscopic pancreaticoduodenectomy118 Establishment of a collaborative group to conduct innovative clinical trials in Canada119 Hepatic resection for metastatic malignant melanoma: a systematic review and meta-analysis120 Acellular normothermic ex vivo liver perfusion for donor liver preservation121 Pancreatic cancer and predictors of survival: comparing the CA 19–9/bilirubin ratio with the McGill Brisbane Scoring System122 Staged liver resections for bilobar hepatic colorectal metastases: a single centre experience123 Economic model of observation versus immediate resection of hepatic adenomas124 Resection of colorectal liver metastasis in the elderly125 Acceptable long-term survival in patients undergoing liver resection for metastases from noncolorectal, non-neuroendocrine, nonsarcoma malignancies126 Patient and clinicopathological features and prognosis of CK19+ hepatocellular carcinomas: a case–control study127 The management of blunt hepatic trauma in the age of angioembolization: a single centre experience128 Liver resections for noncolorectal and non-neuroendocrine metastases: an evaluation of oncologic outcomes129 Developing an evidence-based clinical pathway for patients undergoing pancreaticoduodenectomy130 Hepatitis C infection and hepatocellular carcinoma in liver transplant: a 20 year experience131 The effect of medication on the risk of post-ERCP pancreatitis132 Temporal trends in the use of diagnostic imaging for patients with hepato-pancreato-biliary (HPB) conditions: How much ionizing radiation are we really using?196 A phase II study of aggressive metastasectomy for intra-and extrahepatic metastases from colorectal cancer133 Why do women choose mastectomy for breast cancer treatment? A conceptual framework for understanding surgical decision-making in early-stage breast cancer134 Synoptic operative reporting: documentation of quality of care data for rectal cancer surgery135 Learning curve analysis for cytoreductive surgery: a useful application of the cumulative sum (CUSUM) method136 Pancreatic cancer is strongly associated with a unique urinary metabolomic signature137 Concurrent neoadjuvant chemo/radiation in locally advanced breast cancer138 Impact of positron emission tomography on clinical staging of newly diagnosed rectal cancer: a specialized single centre retrospective study139 An evaluation of intraoperative Faxitron microradiography versus conventional specimen radiography for the excision of nonpalpable breast lesions140 Comparison of breast cancer treatment wait-times in the Southern Interior of British Columbia in 2006 and 2010141 Factors affecting lymph nodes harvest in colorectal carcinoma142 Laparoscopic adrenalectomy for metastases143 You have a message! Social networking as a motivator for fundamentals of laparoscopic surgery (FLS) training144 The evaluation and validation of a rapid diagnostic and support clinic for women assessment for breast cancer145 Oncoplastic breast surgery: oncologic benefits and limitations146 A qualitative study on rectal cancer patients’ preferences for location of surgical care147 The effect of surgery on local recurrence in young women with breast cancer148 Elevated IL-6 and IL-8 levels in tumour microenvironment is not associated with increased serum levels in humans with Pseudomyxoma peritonei and peritoneal mesothelioma149 Conversion from laparoscopic to open approach during gastrectomy: a population-based analysis150 A scoping review of surgical process improvement tools (SPITs) in cancer surgery151 Splenectomy during gastric cancer surgery: a population-based study152 Defining the polo-like kinase 4 (Plk4) interactome in cancer cell protrusions153 Neoadjuvant imatinib mesylate for locally advanced gastrointestinal stromal tumours154 Implementing results from ACOSOG Z0011: Practice-changing or practice-affirming?155 Should lymph node retrieval be a surgical quality indicator in colon cancer?156 Long-term outcomes following resection of retroperitoneal recurrence of colorectal cancer157 Clinical research in surgical oncology: an analysis of clinicaltrials.gov158 Radiation therapy after breast conserving surgery: When are we missing the mark?159 The accuracy of endorectal ultrasound in staging rectal lesions in patients undergoing transanal endoscopic microsurgery160 Quality improvement in gastrointestinal cancer surgery: expert panel recommendations for priority research areas161 Factors influencing the quality of local management of ductal carcinoma in situ: a cohort study162 Papillary thyroid microcarcinoma: Does size matter?163 Hyperthermic isolated limb perfusion for extremity soft tissue sarcomas: systematic review of clinical efficacy and quality assessment of reported trials164 Adherence to antiestrogen therapy in seniors with breast cancer: How well are we doing?165 Parathyroid carcinoma: Challenging the surgical dogma?166 A qualitative assessment of the journey to delayed breast reconstruction195 The role of yoga therapy in breast cancer patients167 Outcomes reported in comparative studies of surgical interventions168 Enhanced recovery pathways decrease length of stay following colorectal surgery, but how quickly do patients actually recover?169 The impact of complications on bed utilization after elective colorectal resection170 Impact of trimodal prehabilitation program on functional recovery after colorectal cancer surgery: a pilot study171 Complex fistula-in-ano: Should the plug be abandoned in favour of the LIFT or BioLIFT?172 Prognostic utility of cyclooxygenase-2 expression by colon and rectal cancer173 Laparoscopic right hemicolectomy with complete mesocolic excision provides acceptable perioperative outcomes but is complex and time-consuming: analysis of learning curves for a novice minimally invasive surgeon174 Intraoperative quality assessment following double stapled circular colorectal anastomosis175 Improving patient outcomes through quality assessment of rectal cancer care176 Are physicians willing to accept a decrease in treatment effectiveness for improved functional outcomes for low rectal cancer?177 Turnbull-Cutait delayed coloanal anastomosis for the treatment of distal rectal cancer: a prospective cohort study178 Preoperative high-dose rate brachytherapy in preparation for sphincter preservation surgery for patients with advanced cancer of the lower rectum179 Impact of an enhanced recovery program on short-term outcomes after scheduled laparoscopic colon resection180 The clinical results of the Turnbull-Cutait delayed coloanal anastomosis: a systematic review181 Is a vertical rectus abdominus flap (VRAM) necessary? An analysis of perineal wound complications182 Fistula plug versus endorectal anal advancement flap for the treatment of high transsphincteric cryptoglandular anal fistulas: a systematic review and meta-analysis183 Maternal and neonatal outcomes following colorectal cancer surgery184 Transanal drainage to treat anastomotic leaks after low anterior resection for rectal cancer: a valuable option185 Trends in colon cancer in Ontario: 2002–2009186 Validation of electronically derived short-term outcomes in colorectal surgery187 A population-based assessment of transanal and endoscopic resection for adenocarcinoma of the rectum188 Laparoscopic colorectal surgery in the emergency setting: trends in the province of Ontario from 2002 to 2009189 Prevention of perineal hernia after laparoscopic and robotic abdominoperineal resection: review with case series of internal hernia through pelvic mesh which was placed in attempt to prevent perineal hernia190 Effect of rectal cancer treatments on quality of life191 The use of antibacterial sutures as an adjunctive preventative strategy for surgical site infection in Canada: an economic analysis192 Impact of socioeconomic status on colorectal cancer screening and stage at presentation: preliminary results of a population-based study from an urban Canadian centre193 Initial perioperative results of the first transanal endoscopic microsurgery (TEM) program in the province of Quebec194 Use of negative pressure wound therapy decreases perineal wound infections following abdominal perineal resection." Canadian Journal of Surgery 55, no. 4 Suppl 1 (2012): S63—S135. http://dx.doi.org/10.1503/cjs.016712.

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Gummaluri, Shiva Shankar, Chandra Mouli Yernagula, Sai Karthikeyan S S, and Shiva Manjunath R G. "Treatment of Vertical Intrabony Defect using a Novel Entire Papilla Preservation Flap Technique with bone graft and Titanium Platelet Rich Fibrin: A Case Report." UNIVERSITY JOURNAL OF DENTAL SCIENCES 9, no. 1 (2022). http://dx.doi.org/10.21276//ujds.2023.9.1.12.

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Treatment of intrabony defects is always a difficult task to manage for a periodontist. Various problems have been encountered like black triangle, increased food lodgement, plaque accumulation and ultimately failure of procedure were experienced. Thus more conservative approaches like papilla preservation flaps and Non-incised Papillae surgical approaches are preferred. But due to drawbacks of existent techniques there was an introduction of novel surgical technique, the Entire Papilla preservation Flap (EPPF). The present case report is a detailed description of treatment of vertical intrabony defect using EPPF technique, bone graft and titanium platelet rich fibrin membrane with 9 months follow up.
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Olivia, Sandra, Natalina Natalina, and Felix Hartono. "Papilla Preservation Flap as Aesthetic Consideration in Periodontal Flap Surgery." Journal of Dentistry Indonesia 19, no. 3 (2013). http://dx.doi.org/10.14693/jdi.v19i3.144.

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Trombelli, L., A. Simonelli, A. Quaranta, et al. "Effect of Flap Design for Enamel Matrix Derivative Application in Intraosseous Defects." JDR Clinical & Translational Research, June 19, 2020, 238008442093473. http://dx.doi.org/10.1177/2380084420934731.

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Objective: To systematically review the literature addressing the focused question: What is the effectiveness of different surgical and nonsurgical procedures combined with enamel matrix derivative (EMD) on clinical, radiographic, and patient-centered outcomes in intraosseous defects? Methods: Electronic (Medline, Scopus, and Cochrane databases) and hand literature searches were performed for studies including at least 1 treatment arm where EMD had been applied according to 1 of the following procedures: modified Widman flap; papilla preservation variants (PPVs), including papilla preservation technique, modified papilla preservation technique, and simplified papilla preservation technique; minimally invasive variants, including minimally invasive surgical approach and minimally invasive surgical technique; single-flap variants (SFVs), including single-flap approach and modified minimally invasive surgical technique; or nonsurgical application (flapless approach). Data from 42 selected articles were used to perform a network meta-analysis, and a hierarchy of surgical and nonsurgical applications of EMD was built separately for EMD and EMD + graft based on 6- to 12-mo clinical and radiographic outcomes. Results: Among surgical approaches, EMD was associated with best regenerative outcomes when applied through SFVs, with a mean clinical attachment level gain of 3.93 mm and a reduction in the intrabony component of the defect of 3.35 mm. For EMD + graft, limited differences in regenerative outcomes were observed among surgical procedures. PPVs were associated with the highest residual probing depth for EMD (4.08 mm) and EMD + graft (4.32 mm). Conclusions: In the treatment of periodontal intraosseous defects, 1) SFVs appear to optimize the regenerative outcomes of EMD; 2) substantial regenerative outcomes can be obtained with SFVs and conservative double flaps (i.e., PPVs and minimally invasive variants) when EMD is combined with a graft; and 3) residual probing depth was higher following PPVs for EMD and EMD + graft. Knowledge Transfer Statement: The results of the present systematic review and meta-analysis can be used by clinicians to identify the most effective surgical or nonsurgical procedure to treat an intraosseous defect with EMD or EMD + graft. The main findings indicate that when EMD application is indicated, surgical access based on a single flap seems the most appropriate to optimize clinical outcomes. The application of EMD + graft can be effectively combined with single flaps and conservative double flaps.
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Ihara, Yuichiro, Shunichi Shibazaki, Satoru Morikawa, and Taneaki Nakagawa. "Novel triangle papilla access approach for interdental bone defect regeneration: A case study." Clinical Advances in Periodontics, January 15, 2025. https://doi.org/10.1002/cap.10335.

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AbstractBackgroundSuccessful periodontal regeneration depends on primary wound closure and interdental papilla preservation. In this case study, we introduce a novel triangle papilla access approach (T‐PAA) performed under a surgical microscope for treating interdental bone defects. In this novel approach, buccal incisions were used to access root surfaces and bone defects, avoiding interdental papilla incisions and preventing papillary collapse and necrosis.MethodsNine patients with a mean age of 56 years were enrolled in this study. Incisions were made to create a triangular flap, which was reflected using a micro‐periosteal elevator to expose the bone defect and granulation tissue. Subsequently, the granulation tissue was removed from the bone defect using a microsurgical blade, followed by root debridement using ultrasonic and micro‐hand scalers and root conditioning. Thereafter, a mixture of fibroblast growth factor‐2 and carbonated apatite granules was applied to the bone defect. The triangular flap was repositioned to ensure that the apex was not lifted by the graft material, and from the flap apex, 7‐0 nylon sutures were used, followed by the addition of mesial and distal sutures. Adjacent teeth were splinted using wire and resin cement.ResultsPostoperatively, clinical and radiographic evaluations at 6 months and 1 year showed significant improvements in periodontal parameters and bone filling. All patients achieved primary wound closure with no postoperative complications.ConclusionsT‐PAA is a promising approach for periodontal regeneration, providing adequate surgical access under a surgical microscope while preserving the papilla and potentially improving clinical outcomes in patients with interdental bone defects.Key points Triangle papilla access approach (T‐PAA) provides adequate surgical access, preserves the interdental papillae, and improves clinical outcomes in cases of interdental bone defects. Triangular incisions made in areas with abundant blood flow and thicker gingiva at the base of the papilla are less likely to impair blood supply to the interdental papillae. T‐PAA facilitates effective debridement, precise placement of regenerative materials, and accurate flap repositioning regardless of the defect morphology in localized interdental areas. Plain language summarySuccessful periodontal treatment often requires surgical procedures for bone regeneration in patients with bone defects. However, traditional surgical approaches may damage the interdental papillae, leading to esthetic concerns and compromised healing. In this study, we introduced a new surgical technique called the triangle papilla access approach, which uses a specially designed triangular incision to access and treat bone defects under a surgical microscope while preserving the interdental papillae. Our results from nine patients demonstrated that this technique effectively maintained tissue health and promoted bone regeneration. Therefore, it could become a more efficient approach for treating interdental bone defects.
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ACIPINAR, Şükran, and Taha Yasin ERDOĞAN. "A Contemporary Approach: Presentation of 4 Cases with the Entire Papilla Preservation (EPP) Technique." Necmettin Erbakan Universitesi Dis Hekimligi Dergisi (NEU Dent J), Necmettin Erbakan, October 15, 2024. http://dx.doi.org/10.51122/neudentj.2024.121.

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Regeneration of periodontal tissue is a primary goal of periodontal treatment. Periodontal regeneration approaches are widely used in the treatment of intraosseous defects. However, the success of these techniques depends on many factors, including surgical considerations. Failures in wound closure in the interdental region, which are surgical factors, have led to the development of papilla preservation techniques. The entire papilla preservation technique (EPP) maintains the integrity of the papilla associated with the defect. This technique stabilizes the blood clot with intact gingiva, preventing wound exposure and contamination. EPP is performed in intra-osseous defects through a short buccal vertical incision, without incising the papilla of the involved tooth. A full-thickness buccal flap is lifted from the incision to the relevant papilla and a tunnel extending under the papilla is prepared. The papilla is also lifted to full thickness. The defect is cleaned of granulation tissue and the wound is closed primarily with or without biomaterial application. In this report, we present 4 cases, 3 in the anterior maxilla and 1 in the mandibular premolar region, undergoing periodontal surgery with EPP with biomaterial application with a 3-month follow-up. In all cases, soft tissue healing was uncomplicated and radiographs showed bone filling at 3 months. EPP has a high success rate in periodontal regeneration by providing complete nutrition of the interdental papilla through natural, continuous vascular support in intraosseous defects.
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Sayegh, Wadie, Ali Khalil, and Nadim Sleman. "Comparative evaluation of modified frenectomy with papilla preservation flap versus conventional technique in upper labial frenectomy: a randomized controlled trial." Annals of Medicine & Surgery, February 28, 2025. https://doi.org/10.1097/ms9.0000000000003073.

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Introduction: Cosmetic concerns among patients have led to an increased demand for dental treatments aimed at achieving a perfect smile. One of the main cosmetic issues in adults is the gap between the upper incisors, known as diastema, and the upper lip frenulum is often a contributing factor to this condition. Therefore, it is imaportant to focus on this aspect. Objective: To explore a new technique for cutting the upper lip frenulum in patients with a gap between the central incisors while avoiding the negative effects of the traditional technique. Materials and methods: This randomized controlled clinical trial included 20 patients diagnosed with abnormal upper lip frenal attachment and diastema between the central incisors. The study compared the modified frenectomy technique with a papilla preservation flap against the traditional “Archer” technique. Each technique was performed on 10 patients, and outcomes such as scar formation, gingival inflammation, and post-surgical pain were evaluated. Results: The “modified frenectomy with papilla preservation flap” technique prevented scar formation in the papilla area between the upper incisors in nine cases, while scar formation occurred in seven cases using the traditional technique. There were no statistically significant differences in gingival inflammation post-surgery. Pain levels were lower with the modified technique: on the first day, the average pain score was 1.5 for the modified technique and 2.8 for the traditional technique. By the third day, the average pain was 4.3 for the modified technique and 6.9 for the traditional technique, with pain decreasing by the seventh day to an average of 0.7 for the modified technique and 1.6 for the traditional technique. Conclusion: The modified frenectomy with a papilla protection flap effectively reduces scarring, enhances healing, and minimizes postoperative pain, offering a more comfortable and aesthetically better result than conventional methods.
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Windisch, Peter, Vincenzo Iorio-Siciliano, Daniel Palkovics, Luca Ramaglia, Andrea Blasi, and Anton Sculean. "The role of surgical flap design (minimally invasive flap vs. extended flap with papilla preservation) on the healing of intrabony defects treated with an enamel matrix derivative: a 12-month two-center randomized controlled clinical trial." Clinical Oral Investigations, September 7, 2021. http://dx.doi.org/10.1007/s00784-021-04155-5.

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Abstract Objectives Minimally invasive flap designs have been introduced to enhance blood clot stability and support wound healing. Limited data appear to suggest, that in intrabony defects, better clinical outcomes can be achieved by means of minimally invasive flap compared to more extended flaps. The aim of this study was to evaluate the healing of intrabony defects treated with either minimally invasive surgical flaps or with modified or simplified papilla preservation techniques in conjunction with the application of an enamel matrix derivative (EMD). Materials and methods Forty-seven subjects were randomly assigned to either test (N = 23) or control (N = 24) procedures. In the test group, the intrabony defects were accessed by means of either minimally invasive surgical technique (MIST) or modified minimally invasive surgical technique (M-MIST) according to the defect localization while the defects in the control group were treated with either the modified or simplified papilla preservation (MPP) or the simplified papilla preservation technique (SPP). EMD was used as regenerative material in all defects. The following clinical parameters were recorded at baseline and after 12 months: full-mouth plaque score (FMPS), full-mouth bleeding score (FMBS), probing depths (PD), clinical attachment level (CAL), and gingival recession (GR). Early healing index (EHI) score was assessed in both groups 1 week following the surgery. CAL gain was set as primary outcome. Results After 12 months follow-up, the CAL gain was 4.09 ± 1.68 mm in test group and 3.79 ± 1.67 mm in control group, while the PD reduction was 4.52 ± 1.34 mm and 4.04 ± 1.62 mm for test and control sites. In both groups, a minimal GR increase (0.35 ± 1.11 mm and 0.25 ± 1.03 mm) was noted. No residual PDs ≥ 6 mm were recorded in both groups. CAL gains of 4–5 mm were achieved in 30.4% and in 29.2% of test and control group, respectively. Moreover, CAL gains ≥ 6 mm were recorded in 21.7% of experimental sites and in 20.8% of control sites. No statistically significant differences in any of the evaluated parameters were found between the test and control procedures (P &gt; 0.05). After 1 week post-surgery, a statistically significant difference (P &lt; 0.05) between the groups was found in terms of EHI score. Conclusions Within the limits of this pilot RCT, the results have failed to show any differences in the measured parameters following treatment of intrabony defects with EMD, irrespective of the employed surgical technique. Clinical relevance In intrabony defects, the application of EMD in conjunction with either MIST/M-MIST or M-PPT/SPPT resulted in substantial clinical improvements.
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Noha, A. Ghallab. "Clinical and Radiographic Evaluation of Papilla Preservation Flap with or without Nanocrystalline Hydroxyapatite Bone Graft for Management of Periodontal Intrabony Defects: A Randomized Controlled Clinical Trial." September 3, 2021. https://doi.org/10.19070/2377-8075-21000856.

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This study assessed clinically and radiographically nanocrystalline hydroxyapatite bone graft substitute (n-HA) with papilla preservation flap (PPF) versus PPF alone in treatment of periodontal intrabony defects. Thirty patients with periodontitis were randomly allocated to receive either PPF+n-HA (intervention group) or PPF (control group). Plaque index, gingival index, probing pocket depth (PPD), clinical attachment level (CAL), and radiographic bone defect area (BDA) were recorded at baseline, 3 and 6 months postoperatively. Both groups showed a significant improvement (P&le;0.05) in all parameters 6 months postoperatively without significant difference (P&ge;0.05) between them. After 6 months, PPF+n-HA demonstrated 3.67 (&plusmn;1.07)mmPPD reduction and 3.33 (&plusmn;0.89)mm CAL gain, while PPF showed PPD reduction of 3.58 (&plusmn;1.31)mm and 2.67 (&plusmn;1.3) mm CAL gain. The BDA reduced by 3.61(&plusmn;2.46) mm2 in PPF+n-HA and 2.02 (&plusmn;1.76)mm2 in PPF group.Both PPF+n-HA and PPF groups improved clinical and radiographic outcomes and were effective in managing intrabony defects.
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Cui, Yue, Yuhe Mai, Xuewei Liu, and Hong Mu. "Clinical benefits of autologous platelet concentrate in periodontal intrabony defects: A network meta‐analysis of randomized controlled trials." European Journal of Oral Sciences, March 8, 2024. http://dx.doi.org/10.1111/eos.12978.

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AbstractThis study aimed to compare clinical benefits of autologous platelet concentrate with other periodontal regenerative approaches in intrabony defects. An electronic and hand search of studies up to December 2022 was conducted. Randomized controlled trials with at least 6 months of follow‐up were identified to compare autologous platelet concentrates with enamel matrix derivative, bone graft, guided tissue regeneration, and open‐flap debridement. All approaches involved papilla preservation flap surgery. The outcomes included probing depth reduction, clinical attachment level gain, linear bone fill, and safety. A network meta‐analysis and meta‐regression were performed. Fifty‐seven studies were included in five network meta‐analyses. Autologous platelets concentrate and its adjunct treatments achieved significantly greater clinical and radiographic parameters than did open‐flap debridement, and had comparable or better performance than other regenerative treatments. Platelet‐rich fibrin showed superiority over platelet‐rich plasma in probing depth reduction at 6‐month follow‐up. Minimal pain and improved wound healing were observed in the treatments with autologous platelet concentrate. Meta‐regression showed that deeper baseline intrabony defects resulted in larger probing depth reductions, while smoking impaired the effectiveness of regenerative surgeries. Minimal invasive flap designs led to less effect of regenerative materials. Autologous platelet concentrate is a promising biomaterial in periodontal regeneration due to its convenience, safety, and biocompatibility characteristics.
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37

MURATI, Bashkim, and Arben MUCAJ. "POST DENTAL AND ORAL – MAXILLOFACIAL IMPLANT NEUROPATHY OF TRIGEMINAL NERVE." Buletini Shkencor Reald 7, no. 1 (2022). http://dx.doi.org/10.59858/bshr10031.

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The introduction and application of ad hoc- flap designs for accessing even deep intrabony defects has led to a significant improvement in reconstructive outcomes after the use of guided tissue regeneration (GTR, Guided Tissue Regeneration) or enamel matrix derivatives (EMD). Although the additional beneficial effects of GTR and EMD are now known, in association with open curettage alone, the improvements in surgical techniques, in particular the introduction of new papilla preservation procedures, have resulted in a progressive increase in clinical attachment gain achievable with open curettage alone. The Single Flap Approach (SFA) is a simplified surgical procedure specifically designed for the treatment of periodontal bone defects. The key principle of this procedure consists in the elevation of a single mucoperiosteal access flap (buccal or oral), preserving the integrity of the interproximal supracrustal soft tissues. The article, in addition to the the oretical research and studies to date on the advantages of this surgical technique, brings in a detailed analysis the clinical case treated by the authors, analyzing the entire procedure step by step. Scientific research and their application in clinical cases have shown that SFA allows to minimize the trauma of the interproximal soft tissues by bringing reduced recession after surgery.
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Shehu, Erion, Estela Halimi, Brunilda Koçi, Edlira Deda, and Ilir Shehu. "SURGICAL TREATMENT OF PERIODONTAL BONE DEFECTS THROUGH THE APPLICATION OF THE “SINGLE FLAP APPROACH” TECHNIQUE AND BIOMATERIALS." Buletini Shkencor Reald 7, no. 1 (2022). http://dx.doi.org/10.59858/bshr10041.

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The introduction and application of ad hoc- flap designs for accessing even deep intrabony defects has led to a significant improvement in reconstructive outcomes after the use of guided tissue regeneration (GTR, Guided Tissue Regeneration) or enamel matrix derivatives (EMD). Although the additional beneficial effects of GTR and EMD are now known, in association with open curettage alone, the improvements in surgical techniques, in particular the introduction of new papilla preservation procedures, have resulted in a progressive increase in clinical attachment gain achievable with open curettage alone. The Single Flap Approach (SFA) is a simplified surgical procedure specifically designed for the treatment of periodontal bone defects. The key principle of this procedure consists in the elevation of a single mucoperiosteal access flap (buccal or oral), preserving the integrity of the interproximal supracrustal soft tissues. The article, in addition to the the oretical research and studies to date on the advantages of this surgical technique, brings in a detailed analysis the clinical case treated by the authors, analyzing the entire procedure step by step. Scientific research and their application in clinical cases have shown that SFA allows to minimize the trauma of the interproximal soft tissues by bringing reduced recession after surgery.
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39

Subramanian, Sangeetha, Prakash PSG, Vijayanth Singh, et al. "The Effect of Platelet-Rich Fibrin and Low-Level Laser Therapy Associated with Simplified Papilla Preservation Flaps in the Management of Supra-Alveolar Periodontal Defects." Odovtos - International Journal of Dental Sciences, January 16, 2025, 174–85. https://doi.org/10.15517/ijds.2025.63492.

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The current study aimed to evaluate and compare the effect of Platelet Rich Fibrin (PRF) and Low-Level Laser Therapy (LLLT) on the clinical outcomes when supraalveolar defects were accessed with Simplified Papilla Preservation Flap (SPPF). Forty-five patients presenting with supra-alveolar defects were allocated into three study groups with 15 patients in each group. SPPF approach was performed in each group with the addition of PRF and LLLT in the test groups. In all the study groups, a significant reduction in pocket depth was observed (P&lt;0.001) at 6 months after therapy. The Relative Attachment Gain was significantly higher in the PRF Group (P&lt;0.001) and in the Control Group (P=0.02) at six months compared to baseline. The study groups failed to show significant differences between them when clinical parameters were compared at six months.
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40

Jundaeng, Jarupat, Rapeeporn Chamchong, and Choosak Nithikathkul. "Dental implant in esthetic zone: A case report." SAGE Open Medical Case Reports 13 (January 2025). https://doi.org/10.1177/2050313x241311702.

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This case report emphasizes the complexities involved in dental implant placement within the anterior esthetic zone, focusing on the integration of advanced surgical techniques and meticulous prosthetic design for optimal esthetic and functional results. A 28-year-old male presented with the absence of the upper left central incisor, which had been extracted 5 years prior due to fracture. Clinical and radiographic assessments indicated normal alveolar bone levels; however, the esthetic demands required a specialized approach. The surgical procedure included a papilla preservation flap, immediate implant placement, and bone grafting to prevent peri-implant resorption and achieve an optimal emergence profile. An Osstem implant and resorbable Xenograft were utilized to address the thin labial bone. Over 4 months, successful osseointegration occurred, followed by the placement of a permanent crown. This case illustrates that dental implant restoration in the anterior esthetic zone can effectively address functional and esthetic challenges, leading to high patient satisfaction with the final restoration’s natural appearance.
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Ho, King‐Lun Dominic, Ka‐Leong Ryan Ho, George Pelekos, Wai‐Keung Leung, and Maurizio S. Tonetti. "Endoscopic Re‐Instrumentation of Intrabony Defect–Associated Deep Residual Periodontal Pockets Is Non‐Inferior to Papilla Preservation Flap Surgery: A Randomized Trial." Journal of Clinical Periodontology, October 17, 2024. http://dx.doi.org/10.1111/jcpe.14075.

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ABSTRACTBackground and AimClinical practice guidelines suggest access flap surgery for managing deep residual pockets after steps 1 and 2 of periodontal therapy. Papilla‐preservation flap surgery (PPFS) is the least invasive approach to access and instrument biofilm‐contaminated root surfaces. Endoscopic‐assisted subgingival debridement (EASD) may enhance the outcomes of repeated instrumentation and provide a minimally invasive non‐surgical alternative.MethodsThis was a single‐blind, controlled, randomized, parallel‐group, non‐inferiority 12‐month trial comparing EASD with PPFS. Male and female adults with generalized stage III periodontitis and persistent periodontal pockets associated with an intrabony defect after steps 1 and 2 of periodontal therapy were recruited at Prince Philip Dental Hospital. Inter‐group differences in clinical attachment level (CAL) changes at 12 months were the primary outcome. Secondary outcomes included pocket resolution (no pocket &gt; 5 mm and no pocket &gt; 4 with bleeding on probing), radiographic bone changes, treatment time, early wound healing and quality‐of‐life measurements.ResultsSixty‐two subjects (30 EASD and 32 PPFS) were included in the intention‐to‐treat analysis. CAL gains were 2.0 ± 1.0 and 1.8 ± 1.0 mm for test and controls, respectively. The 95% CI of the inter‐group difference was −0.3 to 0.8 mm and within the stipulated 1‐mm non‐inferiority margin. No inter‐group differences were observed (i) in pocket resolution, which was achieved in more than 87% of cases for all groups/time points, and (ii) in radiographic bone healing. The treatment time was significantly shorter for EASD than for PPFS. Better early wound healing index scores were observed for EASD. No inter‐group differences in pain, quality of life or safety were detected.ConclusionsEASD was not inferior to PPFS for managing residual pockets associated with intrabony defects. The observed outcome profile supports additional developments and studies to validate EASD as an alternative to surgery for isolated persistent pockets (ChiCTR‐INR‐16008407).
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Rasperini, Giulio, Emilia Kazarian, and Serhat Aslan. "Coronally Advanced - Entire Papilla Preservation Flap (CA-EPP) in the Treatment of Isolated Intrabony Defect to Promote Buccal and Interproximal Soft Tissue Stability: Case Reports." International Journal of Periodontics & Restorative Dentistry, 2023. http://dx.doi.org/10.11607/prd.6851.

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43

Ghallab, Noha A. "Clinical and Radiographic Evaluation of Papilla Preservation Flap with or without Nanocrystalline Hydroxyapatite Bone Graft for Management of Periodontal Intrabony Defects: A Randomized Controlled Clinical Trial." International Journal of Dentistry and Oral Science, September 3, 2021, 4201–8. http://dx.doi.org/10.19070/2377-8075-21000856.

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44

Montiel-López, Patricia A., Juan C. García-Nuñez, Mari L. Muro-Jiménez, et al. "Management of intrabony defects associated with the iatrogenic use of orthodontic elastic bands: A case report." World Journal of Clinical Cases 13, no. 20 (2025). https://doi.org/10.12998/wjcc.v13.i20.105685.

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BACKGROUND The generation of intrabony defects due to the iatrogenic use of elastic bands is an undesirable situation that can result in persistent gingival inflammation with subsequent bone degradation, thus ultimately leading to tooth loss. CASE SUMMARY This clinical case involved a 27-year-old male patient who complained of persistent inflammation and bleeding in the upper anterior region of the gums, despite having undergone dental cleaning for at least 4 years. The dental and medical history indicated the use of removable orthodontic appliances for 8 years, after which braces were placed for 2 years. The intraoral evaluation revealed inflammation and localized suppuration in teeth 11 and 12. Measurements of 2-7 mm for probing depth and 1-5 mm for clinical attachment loss were detected, and combined bone loss was observed via radiographs. Based on the clinical and radiographic findings, localized stage III, grade C periodontitis was diagnosed. During subgingival debridement, two elastic bands emerged around the involved teeth. The bone defects persisted; therefore, they were surgically addressed using a papilla preservation flap and guided tissue regeneration (GTR). CONCLUSION The use of elastic bands of various sizes and elasticities is often essential in multiple orthodontic treatments. However, it is crucial to perform a thorough check-up for each patient during treatment and at the end of treatment to remove any remaining residue of resin, metal bands, or orthodontic bands. Additionally, it is imperative to inform the patients of the importance of attending their follow-up appointments. The use of elastic bands in orthodontics requires special care; moreover, GTR is a management option for intrabony defects associated with the iatrogenic use of bands.
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45

Guimarães, Tarcísio Guerra, Fabricio Villela Mamede, Emilio Fernandes Rodrigues Junior, Paulo Pimenta, and Karla Menezes Cardoso. "Intrascleral Prosthesis in a Dog - Evisceration and Implantation." Acta Scientiae Veterinariae 50 (January 2, 2022). http://dx.doi.org/10.22456/1679-9216.119512.

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Background: There is no hope of preserving vision at the terminal stage of glaucoma, and surgical treatment is indicated in these cases. Among the various surgical techniques used, eye evisceration with implantation of an intrascleral prosthesis provide the best cosmetic results. Even though eye evisceration with prosthesis implantation represents an excellent treatment option for terminal glaucoma, reports on the use of this technique in dogs are scarce in the current literature. The aim of this work is to report a case of a dog with end-stage glaucoma subjected to eye evisceration surgery and implantation of an intrascleral prosthesis. Case: A 7-year-old bitch mixed breed with a history of glaucoma secondary to uveitis with no response to medical therapy was referred to the Ophthalmology service of the University Veterinary Hospital of Coimbra (HVUC), Portugal At the ophthalmic examination, the glaucomatous left eye was buphthalmic, with congested episcleral blood vessels, mydriasis, and posterior luxation of the lens; there was no response to threat or obfuscation, no direct and consensual pupillary reflex, nor pupillary reflexes to chromatic light. The intraocular pressure (IOP) was 55 mmHg, and the Schirmer’s tear test (STT-1) result was 19 mm/min. Ophthalmoscopy revealed attenuated retinal blood vessels and a pale optic papilla with mild excavation. The right eye was functional, with all parameters assessed on examination and by tests within the normal ranges for the species. An ultrasound examination of the left eye confirmed the presence of posterior luxation of the lens and buphthalmia in the absence of intraocular neoplasm. In view of the patient’s history and results of the clinical examinations, a surgical approach was indicated to treat the glaucomatous eye. The patient’s tutor requested a surgical procedure that produced a more natural aspect; therefore, the procedure chosen was evisceration, with implantation of an intrascleral prosthesis. The prosthesis diameter chosen was 2 mm greater than the horizontal diameter of the cornea of the functional eye. After evisceration, a black spherical silicone prosthesis of 20 mm in diameter was implanted through a scleral incision. The eye surface was protected with a nictitating membrane flap. In the postoperative period, the cornea exhibited areas with neovascularization, pigmentation, and fibrosis, with a final aspect of gray to black in color. A reduction in tear production was also observed, with no other lesions on the eye surface or major complications. Discussion: Causes of secondary glaucoma include uveitis, disorders of the lens, and neoplasms, among other alterations. Glaucoma can cause clinical signs such as buphthalmic eyes, congestion of the episcleral blood vessels, and increased IOP with nonresponsive mydriasis. The presence of severe degenerative retinal alterations, such as atrophy and excavation of the optic nerve, causes irreversible loss of vision. Surgical treatment is indicated for end-stage glaucoma cases. Eye evisceration with implantation of a prosthesis involves replacement of the intraocular contents by a silicone sphere 1-2 mm larger than the healthy contralateral eye. Protection of the eye surface may be provided using additional procedures such as the nictitating membrane flap. The scleral incision may reduce corneal sensitivity and, consequently, reduce the tear reflex and cause a reduction in STT-1 values. After implantation of the prosthesis, the cornea may exhibit neovascularization, edema, fibrosis, and pigmentation; these are considered expected corneal reactions in the postoperative period. This surgical technique allows treatment of sore and blind eyes, and its results are more aesthetically pleasant compared to other procedures. Preservation of the eyeball with implantation of the prosthesis produced an excellent aesthetic result, with an appearance very close to natural in the case presented here. Keywords: surgery, glaucoma, intraocular prosthesis, silicone. Título: Prótese intraescleral em um cão - evisceração e implantaçãoDescritores: cirurgia, glaucoma, prótese intraocular, silicone.
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Barbato, Luigi, Desirée Noce, Maria Di Martino, et al. "Non‐surgical retreatment versus papillary preservation flap surgery for residual pockets: A randomized controlled trial with clinical and patient‐reported outcomes." Journal of Clinical Periodontology, July 16, 2024. http://dx.doi.org/10.1111/jcpe.14047.

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AbstractAimTo compare the efficacy of non‐surgical re‐instrumentation (NSR) and papillary preservation flap (PPF) surgery at single‐rooted teeth with residual pockets.Materials and MethodsPatients with at least a residual pocket depth (PD ≥ 5 mm) after Steps I and II were enrolled and randomly assigned to receive NSR or PPF surgery. The primary outcome was PD reduction, and secondary outcomes were clinical attachment level (CAL) change and patient‐reported outcome measures (PROMs). Outcome variables were measured at baseline, 3 and 6 months. The examiner was blinded. Statistical analysis, one site for each patient, included descriptive statistics and analysis of covariance.ResultsForty‐six participants were enrolled, and one patient dropped out in the PPF group. After 6 months, both treatments resulted in significant PD reduction (1.3 ± 1.2 mm, p = .009 NSR; 2.0 ± 0.7 mm, p &lt; .001 PPF) and CAL gain (1.0 ± 2.4 mm, p = .031 NSR; 1.4 ± 0.8 mm, p &lt; .001 PPF). PD reduction between groups was not statistically significant (diff: 0.6 mm; 95% confidence interval [CI] [−0.3 to 1.5]; p = .167). Pocket closure was 61% NSR versus 86% PPF (p = .091). Smoking was associated with less PD reduction of almost 1 mm in both treatments. Treatment time was longer for PPF surgery, but PROMs and post‐operative pain were similar between groups.ConclusionsBoth NSR and PPF reduced PD without significant difference between treatments at 6 months. PPF surgery may offer faster PD reduction, but smoking habits reduce treatment efficacy.
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Cairo, Francesco, Raffaele Cavalcanti, Luigi Barbato, et al. "Polynucleotides and Hyaluronic Acid (PN-HA) Mixture With or Without Deproteinized Bovine Bone Mineral as a Novel Approach for the Treatment of Deep Infra-Bony Defects: A Retrospective Case-Series." International Journal of Periodontics & Restorative Dentistry, February 16, 2024, 1–24. http://dx.doi.org/10.11607/prd.7065.

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Polynucleotides and Hyaluronic Acid (PN-HA) mixture showed several effects in modulation of healing process. The aim of this study was to assess the safety and clinical performance of PN-HA alone or in association with Deproteinized Bovine Bone Mineral (DBBM) with papillary preservation flaps (PPF) in the treatment of residual pockets. A total of 43 patients with 55 infra-bony defects were recruited; 30% were smokers. The mean baseline Probing Depth (PD) was 7.7 ±1.9 mm with a corresponding mean recession (Rec) of 1.9± 1.3 mm. The depth of infra-bony defect at the surgical measurement was 5.2±2.1 mm. DBBM was applied at 56% of the defects considered as not-containing based on clinical judgment. Healing was uneventful at all sites. After one year, PD reduction was 4.4±1.8 mm with a Rec increase of 1.0 ±0.8 mm. Detected bone fill at x-ray was 3.5 ± 1.9mm. The multilevel analysis showed that absence of smoking habits was associated with improved PD reduction (P =0.026) and bone gain (P= 0.039). PN-HA mixture is a safe product for periodontal surgery and seems to promote clinical benefit in the treatment of residual pockets associated to infra-bony defects.
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