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Dissertations / Theses on the topic 'Parainfluenza viruses'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Wu, Ying, and 武盈. "Discovery and characterization of a novel porcine paramyxovirus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hdl.handle.net/10722/196086.

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Most emerging infectious diseases in humans are zoonotic agents. Since the emergence of severe acute respiratory syndrome (SARS), swine-origin influenza and avian influenza epidemics, the study of novel and emerging viruses with zoonotic potential has been considered more and more important. Paramyxoviruses have been known for their potential to cross species barrier and infect new hosts. In the last decade, a number of novel and emerging paramyxoviruses have been reported in various animals. Our research group recently identified three novel bat paramyxoviruses, Tuhoko viruses 1, 2 and 3 (Thk

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2

Bamford, Anona Isabelle. "Interactions between cytotoxic effector cells and bovine parainfluenza type 3 virus." Thesis, Queen's University Belfast, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241326.

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3

Chan, Yuk-on. "Impact of respiratory viruses on mortality." Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/b39724025.

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4

Norsted, Hanna. "The effect of interferon on the transcription pattern of parainfluenza virus 5." Thesis, University of St Andrews, 2013. http://hdl.handle.net/10023/3403.

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Interferon (IFN) is activated in response to virus infections and upregulates interferon-stimulated genes (ISGs) resulting in the expression of hundreds of proteins, many of which have direct or indirect antiviral activity. Parainfluenza virus 5 (PIV5) of the Paramyxoviridae family is a non-segmented negative sense single-stranded RNA virus with seven genes encoding eight proteins. Here we present that IFN induces alterations in the pattern of both virus transcription and translation and that ISG56 is primarily responsible for these effects. We report that when cells were treated with IFN post

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5

Chan, Yuk-on, and 陳旭安. "Impact of respiratory viruses on mortality." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B39724025.

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6

Alias, Nadiawati. "Multivalent sialic acid binding proteins as novel therapeutics for influenza and parainfluenza infection." Thesis, University of St Andrews, 2014. http://hdl.handle.net/10023/4479.

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In nature, proteins with weak binding affinity often use a multivalency approach to enhance protein affinity via an avidity effect. Interested in this multivalency approach, we have isolated a carbohydrate binding module (CBM) that recognises sialic acid (known as a CBM40 domain) from both Vibrio cholerae (Vc) and Streptococcus pneumoniae (Sp) NanA sialidases, and generated multivalent polypeptides from them using molecular biology. Multivalent CBM40 constructs were designed either using a tandem repeat approach to produce trimeric or tetrameric forms that we call Vc3CBM and Vc4CBM, respective

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7

Baumgärtner, Wolfgang K. "Mechanisms of in vitro persistence of two canine paramyxoviruses and in vivo neuropathogenecity of canine parainfluenza virus /." The Ohio State University, 1986. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487265555440015.

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8

Roth, Jason Peter. "The Use of Reverse Genetics to Clone and Rescue Infectious, Recombinant Human Parainfluenza Type 3 Viruses." DigitalCommons@USU, 2009. https://digitalcommons.usu.edu/etd/467.

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Reverse genetics is a discipline that involves the use of genetic manipulation and modification to study an organism's altered phenotype. In this study, infectious recombinant viruses were rescued from altered cDNA clones encoding the antigenome of human parainfluenza virus type 3 and the resulting phenotypes were examined. In one clone, the gene for the enhanced green fluorescent protein was inserted into the virus antigenome to be expressed during viral replication, resulting in infected cells emitting green fluorescence. Viral titers, mRNA replication, and genomic replication for the vir

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9

Lam, Siu-yan. "Multiplex reverse transcription-PCR for detection and identification of human parainfluenza viruses 1,2,3 and 4 infection in hospitalized children with respiratory disease in Hong Kong /." View the Table of Contents & Abstract, 2007. http://sunzi.lib.hku.hk/hkuto/record/B3848058X.

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10

Xiao, Han. "Virus and interferon : a fight for supremacy : comparison of the mechanisms of influenza A viruses and parainfluenza virus 5 in combatting a pre-existing IFN-induced antiviral state." Thesis, University of St Andrews, 2011. http://hdl.handle.net/10023/2070.

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The Interferon (IFN) family of cytokines are produced in direct response to virus infection and they constitute the first line of defence against virus infection by inducing hundreds of interferon stimulated genes (ISGs) which act in concert to establish the so-called “antiviral state”. Influenza A viruses and parainfluenza virus type 5 (PIV5) are both small negative strand RNA viruses that must circumvent their hosts’ interferon (IFN) response for replication. However, the ways in which these viruses interact with the IFN system are very different. Although PIV5 replication is initially sever

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11

Beneli, Patrícia Costa. "Associação entre fatores meteorológicos, poluentes atmosféricos e ocorrência de viroses respiratórias em crianças: destaque ao Parainfluenza Vírus Humano (HPIV)." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/87/87131/tde-02032011-181725/.

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As infecções respiratórias agudas contribuem para elevada morbimortalidade na infância, destacando o Parainfluenza (HPIV) nos quadros de crupe viral. Pouco é conhecido a influência dos fatores ambientais (meteorológicos e de poluição atmosférica) nas infecções respiratórias. De 21/10/2004 a 01/06/2007 foi conduzido um estudo ecológico de séries temporais, em menores de 15 anos, com sintomas respiratórios atendidos na Santa Casa de São Paulo e no Hospital Universitário de Jundiaí para determinar a freqüência de HPIV, pela imunofluorescência indireta e verificar a relação entre poluentes atmosfé

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12

Lam, Siu-yan, and 林小欣. "Multiplex reverse transcription-PCR for detection and identification of human parainfluenza viruses 1,2,3 and 4 infection in hospitalizedchildren with respiratory disease in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B45011357.

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13

Amaral, Larissa Morais Bomilcar do. "Epidemiologia e caracterização molecular do Vírus Parainfluenza Humano 1, 2 e 3 em crianças menores de 5 anos de idade atendidas no Hospital Universitário em 2007, São Paulo - Brasil." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/42/42132/tde-02022010-093628/.

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O objetivo do presente trabalho é descrever o perfil epidemiológico e molecular dos vírus Parainfluenza em crianças menores de 5 ano de idade, com infecção das vias respiratórias. Por tanto, aspirados de nasofaringe de 742 crianças foram examinadas para os Vírus Parainfluenza Humano(HPIV1, HPIV2 e HPIV3), hRSV, hMPV e IA e IB pela técnica de RT-PCR, durante o ano de 2007. Ao todo foram identificados 52(7%) Parainfluenza vírus, sendo 9(17,3%) HPIV1, 8(15,4%) HPIV2 e 35(67,3%) HPIV3. Destas, 12 (23%) foram casos de coinfecções, sendo 3 (25%) de HPIV3 com VRS, 3 (25%) com MPV e 3 (25%) com HPIV1

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14

Goka, Edward Anthony Chilongo. "Influenza A viruses dual and multiple infections with other respiratory viruses and risk of hospitalization and mortality." Thesis, University of Manchester, 2014. https://www.research.manchester.ac.uk/portal/en/theses/influenza-a-viruses-dual-and-multiple-infections-with-other-respiratory-viruses-and-risk-of-hospitalization-and-mortality(256eb122-a52a-4276-8dc1-28b5a2cc6662).html.

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Introduction: Epidemiological studies have indicated that 5-38% of influenza like illnesses (ILI) develop into severe disease due to, among others, factors such as; underlying chronic diseases, age, pregnancy, and viral mutations. There are suggestions that dual or multiple virus infections may affect disease severity. This study investigated the association between co-infection between influenza A viruses and other respiratory viruses and disease severity. Methodology: Datum for samples from North West England tested between January 2007 and June 2012 was analysed for patterns of co-infection

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15

Schomacker, Henrick. "Rekombinante bovin-humane Parainfluenzaviren Typ 3 als Impfvektoren gegen nicht-virale Antigene." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2008. http://dx.doi.org/10.18452/15785.

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Bei bhPIV3 handelt es sich um ein bovines Parainfluenzavirus Typ 3 (bPIV3), dessen Ober-flächenproteingene gegen jene des humanen Parainfluenzavirus Typ 3 (hPIV3) ausgetauscht wurden. Dieses ursprünglich als experimenteller Impfstoff gegen hPIV3 entwickelte Virus wurde darüber hinaus als Impfvektor zur Expression anderer viraler Antigene verwendet. Im Rahmen der hier vorgestellten Arbeit wurden die ersten bhPIV3-basierten Vektoren für nicht-virale Antigene hergestellt und in einem ersten Versuch evaluiert. Dazu wurden ein reverses Genetiksystem zur Herstellung rekombinanter bhPIV3 in einem neu

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16

Saffran, Holly Anne. "Regulation of human parainfluenza virus type 3 transcription." Thesis, University of Ottawa (Canada), 1995. http://hdl.handle.net/10393/9503.

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To elucidate the roles of the junctional elements in HPIV3 transcription, cDNAs were constructed containing CAT and luciferase reporter genes flanked by sequences representing the HPIV3 termini necessary for transcription, replication and packaging. Mutations to the gene end sequence abolished expression of the upstream and downstream genes. Deleting the gene start sequence at the junction resulted increased expression of the upstream gene, but abrogated downstream gene activity. Alterations in the length of the intergenic trinucleotide resulted in decreased expression of both upstream and dow

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17

Chapman, Amanda Ruth. "Regulation of the human parainfluenza virus (hPIV3) fusion protein." View the abstract Download the full-text PDF version, 2008. http://etd.utmem.edu/ABSTRACTS/2008-048-Chapman-index.htm.

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Thesis (M.S.)--University of Tennessee Health Science Center, 2008.<br>Title from title page screen (viewed on January 6, 2009). Research advisor: Charles J. Russell, Ph.D. Document formatted into pages (ix, 41p. : ill.). Vita. Abstract. Includes bibliographical references (p. 38-41).

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18

Smielewska, Anna Alexandra. "Human parainfluenza virus 3 : genetic diversity, virulence and antiviral susceptibility." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/287954.

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Human parainfluenza 3 (HPIV3) is a member of the Paramyxoviridae, a single strain negative-sense non-segmented RNA virus in the order Mononegavirales. It is a respiratory pathogen with a broad spectrum of presentations for which there is currently neither a vaccine nor licensed treatment for HPIV3. To date most research on HPIV3 has been conducted using significantly culture adapted reference strains. Therefore, minimally adapted clinical strains were grown in two cell culture systems: immortalised and primary. Plaque phenotype, growth kinetics and inflammatory response triggered were evaluate

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19

Murphy, Lise. "Regulation of human parainfluenza virus type 3 fusion protein expression." Thesis, University of Ottawa (Canada), 2004. http://hdl.handle.net/10393/26723.

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Human parainfluenza virus type 3 (HPIV3) is an enveloped, negative-strand, non-segmented RNA virus. HPIV3 is a human respiratory pathogen that primarily causes diseases such as croup, bronchiolitis and pneumonia in children. The virus has two glycoproteins that allow it to interact with host cells, the receptor binding protein hemagglutinin-neuraminidase (HN) and the fusion protein (F), which enables the virus to enter the cell by fusion of the viral envelope to the target cell plasma membrane. This research was initiated with the goal of determining mechanisms by which HPIV3 regulates the exp

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20

Jogalekar, Prachi. "Analysis of gene junction sequences of human parainfluenza virus type 3." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0019/MQ58465.pdf.

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21

Chidgey, Sharon Michelle. "Airway function, inflammation and pulmonary histopathology following parainfluenza-3 virus infection." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/55663/.

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Human parainfluenza viruses (PIV) 1, 2, 3 and 4 (A and B) cause approximately 39-40% of all acute respiratory infections in infants and children for which there is no effective therapy. Firstly, this thesis was aimed at ascertaining a suitable guinea pig model of PIV-3 infection by determining the most efficient route of virus application. Secondly, to ascertain if a temporal association may be established during the time course of infection (Day 1-40) by measuring the following parameters: body weight, rectal temperature, airway function (sGaw), airways reactivity to inhaled histamine, inflam

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22

Bradford, Hannah Elizabeth Linda. "Cell-mediated immunity to parainfluenza type 3 virus in young calves." Thesis, Queen's University Belfast, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.334497.

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23

Sieg, Scott F. "Infection and immunoregulation of T lymphocytes by parainfluenza virus type 3." Case Western Reserve University School of Graduate Studies / OhioLINK, 1996. http://rave.ohiolink.edu/etdc/view?acc_num=case1057593999.

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24

Short, John A. L. "Defective interfering particles of parainfluenza virus subtype 5 and interferon induction." Thesis, University of St Andrews, 2015. http://hdl.handle.net/10023/7036.

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The innate immune response is the first line of defence against virus infection. Cells contain a diverse array of pathogen recognition receptors (PRRs) that are able to recognise multiple pathogen associated molecular patterns (PAMPS) that present themselves during virus infection. The RIG-I (Retinoic acid inducible–gene-I) and MDA5 (melanoma differentiation- associated gene 5) PRRs detect specific viral RNA ligands and subsequently induce the expression of the cytokine Interferon-β(IFN-β). IFN-βis secreted, acting on the infected cell and neighbouring uninfected cells to generate an antiviral

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25

Storey, Douglas Gordon. "Structural characterization of human parainfluenza virus 3 and cloning of viral specific genes." Thesis, University of Ottawa (Canada), 1987. http://hdl.handle.net/10393/5476.

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26

Murphy, Donald G. "Defective interfering particles of human parainfluenza virus 3 and establishment of persistent infections." Thesis, University of Ottawa (Canada), 1990. http://hdl.handle.net/10393/5615.

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Defective interfering particles of human parainfluenza virus 3 (HPIV3) were generated and/or amplified by serial undiluted passage of the standard virus. Analysis of the progeny virus titer at each cell passage revealed a cyclic pattern of virus production. Viruses produced from serial passages 8 and 9 interfered with replication of the standard virus. When cells were mixedly infected with standard virus and virus from either serial passages 5 or 8, three subgenomic RNA species, in addition to the standard virus genomic RNA, were detected in the progeny virions. Northern blot analysis revealed

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27

Cote, Marie-Jose. "The human parainfluenza virus 3 fusion protein: Cloning, mapping, sequence analysis and expression." Thesis, University of Ottawa (Canada), 1989. http://hdl.handle.net/10393/20781.

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28

Hartwagner, Nadja A. "Dissection of cell entry of Sendai virus and bovine parainfluenza 3 virus by electron microscopy at high resolution /." [S.l.] : [s.n.], 2009. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000286607.

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29

Ebata, Sharon Nori. "Requirements for syncytium formation mediated by the fusion glycoprotein of human parainfluenza virus type 3." Thesis, University of Ottawa (Canada), 1996. http://hdl.handle.net/10393/10423.

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Recombinant vaccinia viruses VF and VHN were shown to express glycoproteins with molecular weights similar to authentic HPIV3 F and HN proteins that were transported to the cell surface and recognized by monoclonal antibodies specific for HPIV3 F and HN. The HN glycoprotein in VHN-infected cells exhibited both hemagglutinin and neuraminidase activities. Both cleaved and uncleaved forms of the F glycoprotein were immunizers from VF-infected cell lysates. Fusogenic activity of the F protein was demonstrated only upon coinfection of HeLa T4$\sp+$ cells with VF + VHN and resulted in syncytium form

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30

Vaucher, Rodrigo de Almeida. "Desenvolvimento de técnicas de RT-PCR para seqënciamento do gene da hemaglutinina-neuraminidase (HN) e detecção do vírus Parainfluenza bovino tipo 3." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2005. http://hdl.handle.net/10183/8932.

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Existem diversos trabalhos publicados sobre a utilização de diferentes métodos imunológicos para diagnosticar infecções do trato respiratório causadas por vírus parainfluenza bovino tipo 3 (bPIV-3). Entretanto, é escassa a literatura sobre a utilização da técnica de isolamento viral. Até o presente momento não havia sido relatada a utilização da Transcrição Reversa - Reação em Cadeia da Polimerase (RT-PCR), na detecção de bPIV-3. O objetivo deste estudo foi contribuir para uma melhor caracterização dos bPIV-3 através do desenvolvimento de técnicas de RTPCR para a sua detecção. Utilizando-se um

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31

Terrier, Olivier. "Les glycoprotéines d'enveloppe des virus Parainfluenza : étude structure versus fonctions et développement d'applications diagnostiques et thérapeutiques." Lyon 1, 2009. http://www.theses.fr/2009LYO10011.

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Les virus parainfluenza humains (hPIV, Famille des Paramyxoviridae) sont des virus respiratoires, souventresponsables d'infections chez les jeunes enfants, les personnes âgées et également les patients immunodéprimés. Ces virus possèdent, à la surface de leur enveloppe, deux glycoprotéines qui jouent toutes les deux un rôle dansl’entrée du virus dans la cellule-cible. L'hémagglutinine-neuraminidase (HN) permet au virus de s'attacher aurécepteur cellulaire. Une fois liée au récepteur, HN "active" la seconde glycoprotéine, la protéine de fusion (F). Cette dernière réalise la fusion entre l'envel

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32

Wheatley, Nicola. "Mapping the haemagglutinin and neuraminidase functions of the human parainfluenza virus type 3 haemagglutinin-neuraminidase protein." Thesis, University of Ottawa (Canada), 1991. http://hdl.handle.net/10393/7739.

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The haemagglutinin-neuraminidase protein (HN) of human parainfluenza virus type 3 is a bifunctional protein. To map the functions to the protein, three truncations of the gene were constructed by digesting the HN gene with the restriction endonucleases Hind III, Bgl II or Xbo I and inserting a stop codon. An internal deletion using Rsa I was also constructed. The four mutants were expressed in the recombinant vaccinia virus system. The expression of the mutant proteins was analysed by both Western Blot and immunoprecipitation. The products of the three truncations migrated at the molecular wei

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33

Hartmann, Tamahine Larronda Schmidt. "Anticorpos neutralizantes contra os vírus da cinomose e parainfluenza caninos em cães e felinos silvestres em cativeiro." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2006. http://hdl.handle.net/10183/8197.

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O vírus da cinomose canina (CDV) e o vírus parainfluenza canino (CPIV) afetam uma ampla variedade de hospedeiros e encontram-se distribuídos mundialmente. O CDV é considerado um dos mais importantes agentes infecciosos dentro das populações caninas. Este vírus é o agente causal da cinomose, uma doença potencialmente letal em membros das famílias Canidae, Mustelidae e Procionidae, sendo recentemente detectado como causa de morbidade e mortalidade em carnívoros aquáticos e grandes felinos. O CPIV, por sua vez, é altamente contagioso entre cães, podendo infectar roedores e gatos em infecções expe

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Ocadaque, Crister JosÃ. "Clinical and epidemiological aspects of children pneumonia associated with four types of parainfluenza virus in Fortaleza-CE." Universidade Federal do CearÃ, 2016. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=16327.

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FundaÃÃo Cearense de Apoio ao Desenvolvimento Cientifico e TecnolÃgico<br>As pneumonias sÃo problemas de saÃde publica mundial, especialmente em crianÃas menores que cinco anos de idade. Os vÃrus parainfluenza (VPI-1, 2 e 3) sÃo agentes frequentes de pneumonia, pouco se conhecendo sobre a participaÃÃo do VPI-4 devido a dificuldades do seu isolamento em cultura de cÃlulas, a ausÃncia de antÃgenos especÃficos para este vÃrus nos painÃis de rotina de detecÃÃo dos vÃrus respiratÃrios, alÃm de serem relacionados apenas a casos de infecÃÃes respiratÃrias leves. O objetivo do presente estudo Ã descre

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35

Gonzalez, Carlos M. "Immunopathological studies in the ovine lung during the course of natural and experimental parainfluenza type 3 virus infection." Thesis, University of Edinburgh, 1996. http://hdl.handle.net/1842/30213.

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The pulmonary immunopathology of parainfluenza type 3(PIV-3) infection in sheep was investigated firstly by isolating the virus from field cases of sheep pneumonia, secondly by experimentally reproducing the disease with the isolated virus and finally by studying changes in lymphocytes subsets and alveolar macrophages, induced by PIV-3 <I>in vivo </I>and <I>in vitro. </I>Three ovine virus isolates(270-7, 390-10 and 430-7) were obtained and characterised, as PIV-3, according to virus morphology, under transmission electron microscopy(TEM); cytopathic effect(CPE); haemagglutination, of guinea pi

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Montesinos, Paredes Milagros de Jesús. "Anticuerpos contra el virus de la Parainfluenza 3 en cerdos de crianza tecnificada y no tecnificada beneficiados en dos mataderos de Lima." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2010. https://hdl.handle.net/20.500.12672/15628.

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Publicación a texto completo no autorizada por el autor<br>El documento digital no refiere asesor<br>El virus de la parinfluenza 3 (VPI3), es uno de los agentes virales involucrados en el complejo respiratorio que afecta principalmente a los bovinos y otras especies. El objetivo del presente estudio fue determinar la seroprevalencia de este agente viral en porcinos del valle de Lima beneficiados en dos mataderos de la ciudad de Lima. Para este fin se colectaron muestras de suero de porcinos de ambos sexos entre 2 a más de 6 meses de edad provenientes de granjas tecnificadas (n= 192) y de

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37

Rai, Vijeta. "Screening of large collection of compounds for anti-human parainfluenza virus type-2 activity and evaluation of hit compounds." Thesis, Högskolan i Skövde, Institutionen för biovetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-14385.

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Human parainfluenza virus type-2 (HPIV-2) is a highly contagious respiratory pathogen that can cause severe respiratory disease known as laryngotracheobronchitis or croup-like disease in children. No specific vaccine or an antiviral drug is currently approved for treatment of HPIV-2 infections. In this project, a library of 14400 diverse compounds had been screened for anti-HPIV-2 activities in cultures of African green monkey kidney cells. All compounds that inhibited the virus induced syncytium-forming activity in these cells were considered as hit compounds. Three hit compounds showed moder

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FÃ, Mariana Mota Moura. "Perfil clÃnico-epidemiolÃgico das infecÃÃes respiratÃrias agudas causadas por vÃrus parainfluenza em crianÃas atendidas em um hospital de referÃncia da cidade de Fortaleza â CE." Universidade Federal do CearÃ, 2007. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=715.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>As infecÃÃes respiratÃrias agudas (IRAs) sÃo um importante problema de saÃde pÃblica em todo o mundo, e os vÃrus parainfluenza estÃo entre os seus agentes mais freqÃentes. Este estudo teve como objetivos: determinar a freqÃÃncia de IRAs pelo vÃrus parainfluenza entre crianÃas atendidas no Hospital Infantil Albert Sabin, hospital pediÃtrico de referÃncia da cidade de Fortaleza â CE, de janeiro de 2001 a dezembro de 2006; descrever o padrÃo de sazonalidade e as caracterÃsticas clÃnico-epidemiolÃgicas destas infecÃÃes; e comparar as c

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39

Sánchez, Salazar Manuel Rodolfo. "Permisibilidad de cultivos celulares secundarios de alpaca y llama a multiplicación viral de herpesvirus bovino, virus de la diarrea viral bovina, virus parainfluenza 3 bovina y virus respiratorio sincitial bovino." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2006. https://hdl.handle.net/20.500.12672/705.

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El objetivo del presente estudio fue determinar la permisibilidad de los cultivos celulares secundarios de alpaca y llama a la infección por distintos agentes virales de conocida seroprevalencia en este tipo de ganado. Se establecieron dos líneas celulares de cornete nasal y piel de alpaca y llama infectándose con Virus de la diarrea viral bovina (VDVB), Virus Herpes Bovino tipo 1 (VHB-1), Virus respiratorio Sincitial Bovino (VRSB) y Virus Parainfluenza bovino tipo 3(VPI-3). Se determinó y caracterizó la presentación de efectos citopatogénicos (ECP) por medio de microscopia óptica de las monoc

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Silva, Bruno Toledo. "Influência dos anticorpos maternos na resposta imune induzida pela vacinação em bezerros Holandeses." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/10/10136/tde-24032016-151529/.

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O objetivo geral desta pesquisa foi avaliar a transferência de imunidade passiva e a sua influência na resposta vacinal para as viroses envolvidas na Doença Respiratória Bovina (DRB). Os dados obtidos nesta pesquisa estão apresentados em dois capítulos. Capítulo 1 - Objetivou-se avaliar a dinâmica de anticorpos (Acs) específicos para as viroses respiratórias e subpopulações de linfócitos em bezerros do nascimento aos 240 dias (d) de vida. Para tanto, acompanhou-se a transferência de imunidade passiva de Acs específicos para as viroses respiratórias em 19 bezerros, destes cinco foram selecion

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Prinoski, Kevin Andrew. "Envelope associated proteins of human parainfluenza virus 3 I. M (matrix) gene sequence, and II. F (fusion) gene sequence comparison among ten isolates." Thesis, University of Ottawa (Canada), 1989. http://hdl.handle.net/10393/5655.

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Monteiro, Francielle Liz. "Detecção molecular de vírus respiratórios em cães." Universidade Federal de Santa Maria, 2015. http://repositorio.ufsm.br/handle/1/10238.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico<br>The respiratory viruses of dogs are associated with a disease called canine infectious respiratory disease (CIRD). The main etiological agents of CIRD are canine distemper virus (CDV), canine parainfluenza virus (cPIV), canine adenovirus type 2 and canid herpesvirus type 1 (CaHV-1), which may cause single or mixed infections. CIRD occurs most frequently in places with high animal density and constant movement. CDV, cPIV, CAdV-2 and CaHV-1 infections have been described worldwide, however, few reports of molecular identification o

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Victorio, Cisneros Willy Mayk. "Seroprevalencia de los virus neumopatógenos de la Parainfluenza bovina 3 (VPI3), Herpesvirus bovino 1 (HVB1) y Virus respiratorio sincitial bovino (VRSB) en alpacas adultas de la provincia de Canchis - Cusco." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2004. https://hdl.handle.net/20.500.12672/2271.

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Con el objetivo de tener una información general sobre la presencia de agentes virales neumotrópicos, se muestreó 345 alpacas adultas procedentes de 31 hatos, pertenecientes a medianos y pequeños criadores de la provincia de Canchis - Cusco. Las muestras de sueros sanguíneos fueron procesadas para la detección de anticuerpos neutralizantes para los virus: Parainfluenza tipo 3 (PI3), Respiratorio Sincitial Bovino (RSB) y el Herpes virus bovino tipo 1 (VHB1). Todas las muestras fueron trabajadas mediante la prueba de neutralización viral utilizando cultivos celulares secundarios de origen bovino

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Cabellos, Rojas Karina Olinda. "Seroprevalencia de los virus : parainfluenza 3, respiratorio sincitial, diarrea viral bovina, en un rebaño mixto de una comunidad campensina de la provincia de Calca, Cusco." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2006. https://hdl.handle.net/20.500.12672/684.

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El presente estudio tuvo como objetivo determinar la seroprevalencia de los agentes neumotrópicos como los virus de la Diarrea Viral Bovina (VDVB), Respiratorio Sincitial (VRS) y Parainfluenza 3 (VPI3) en rumiantes de la comunidad de Chahuaytiri, provincia de Calca, Cusco, a través de la detección de anticuerpos en el suero sanguíneo de alpacas (n igual 21), bovinos (n igual 66) y ovinos (n igual 152) mediante la prueba de neutralización viral (NV). El 15.8±16.4% (3/21), 4.8 ± 9.1% (1/21) y el 23.8±18.2% (5/21) de las alpacas presentaron anticuerpos neutralizantes contra los virus: DVB, RS y P

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Grissett, Gretchen Phoebe. "Systematic review of cattle responses to viral and bacterial bovine respiratory disease pathogens and effect of high ambient temperaure on viral replication and serology to an intranasal modified-live (bovine rhinotracheitis-parainfluenza-3) viral vaccine in beef cattle." Thesis, Kansas State University, 2014. http://hdl.handle.net/2097/18169.

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Master of Veterinary Biomedical Sciences<br>Department of Clinical Sciences<br>Bradley White<br>Objective- To compare serologic response and viral replication following intranasal administration of a modified-live bovine rhinotracheitis (IBR) parainfluenza-3 (PI-3) vaccine in high (32°C) and moderate (21°C) ambient temperatures. Animals- 28 heifers (mean body weight, 206.8 kg) Procedures- Heifers randomly allocated to treatment groups: High Ambient Temperature (HAT, n=10): received vaccine, housed outdoors, Moderate Ambient Temperature (MAT, n=10): received vaccine, housed indoors, High Ambi

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Paris, Fernanda de. "Epidemiologia dos vírus respiratórios e avaliação das características genéticas do vírus sincicial respiratório entre crianças atendidas no Hospital de Clínicas de Porto Alegre." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/70397.

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Introdução: As infecções respiratórias causam elevadas morbidade e mortalidade, sendo os vírus os principais agentes destas doenças. O monitoramento e vigilância de vírus respiratórios, desde os mais conhecidos até os emergentes, são importantes para a gestão em saúde, orientando tempo de profilaxia e minimizando o impacto de epidemias nas comunidades. Objetivos: Estudar a epidemiologia molecular do vírus sincicial respiratório (VSR) e descrever a epidemiologia dos seguintes vírus: influenza (IF), influenza A (H1N1), adenovírus (AdV) e parainfluenza (PIV) no Hospital de Clínicas de Porto Alegr

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Caignard, Grégory. "Cartographie des intéractions entre protéines virales codées par le gène P des Paramyxoviridae et protéines cellulaires." Paris 7, 2010. http://www.theses.fr/2010PA077020.

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La famille des Paramyxoviridae comprend plusieurs virus pathogènes pour l'homme, certains connus depuis longtemps comme le virus de la rougeole (MV), le virus des oreillons (MuV) ou le virus parainfluenza de type 3 (hPIV3), et d'autres identifiés plus récemment comme le virus Nipah (NiV). Dans le cadre d'un programme de cartographie des interactions virus-hôte, mon projet de thèse vise à identifier les cibles cellulaires des protéines codées par le gène P de ces quatre virus ainsi que du virus Tioman (TioV) dont le seul hôte connu à ce jour est la chauve-souris frugivore. J'ai ainsi réalisé 44

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Hanmod, Santosh S. Hewett-Emmett David Peters Ronald J. Chemaly Roy F. "The burden of parainfluenza virus infection in patients with hematological malignancy and hematopoietic stem cell transplant (HSCT) recipients in the absence of active immunization and approved therapy : the role of infection control." 2009. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:1470186.

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Li, Xiantang. "Effects of 4-ipomeanol on bovine parainfluenza type 3 virus induced pneumonia in calves." 1990. http://catalog.hathitrust.org/api/volumes/oclc/23066867.html.

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Thesis (Ph. D.)--University of Wisconsin--Madison, 1990.<br>Typescript. Vita. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references.

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Mao, Shin-Ting, and 毛詩婷. "Production and analysis of monoclonal antibodies against the fiber protein of canine adenovirus and the HN protein of canine parainfluenza virus." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/07685229383000947843.

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碩士<br>國立中興大學<br>分子生物學研究所<br>103<br>Canine adenovirus (CAV) and canine parainfluenza virus (CPiV) were important pathogens to induce kennel cough. The fiber protein on the CAV coat protein is related to virus entry. The hemagglutinin-neuraminidase protein of canine parainfluenza virus (CPiV) could promote virus entry and productive infection. In this study, we deleted the N-terminal 41 and 94 amino acids of CAV and CPiV, respectively and named as CAV-fiber(d41) and CPiV-HN(d94). According to the antigenicity and hydrophilicity of CPiV-HN(d94), three fragments of aa 65-287, aa 288-480 and aa 142

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