Academic literature on the topic 'Paramagnetic MRI agents'

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Journal articles on the topic "Paramagnetic MRI agents"

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White, David L. "Paramagnetic iron (III) MRI contrast agents." Magnetic Resonance in Medicine 22, no. 2 (1991): 309–12. http://dx.doi.org/10.1002/mrm.1910220230.

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Strijkers, G. J., W. J. M. Mulder, R. B. van Heeswijk, et al. "Relaxivity of liposomal paramagnetic MRI contrast agents." Magnetic Resonance Materials in Physics, Biology and Medicine 18, no. 4 (2005): 186–92. http://dx.doi.org/10.1007/s10334-005-0111-y.

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Pellico, Juan, Connor M. Ellis, and Jason J. Davis. "Nanoparticle-Based Paramagnetic Contrast Agents for Magnetic Resonance Imaging." Contrast Media & Molecular Imaging 2019 (May 5, 2019): 1–13. http://dx.doi.org/10.1155/2019/1845637.

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging modality that is routinely used in clinics, providing anatomical information with micron resolution, soft tissue contrast, and deep penetration. Exogenous contrast agents increase image contrast by shortening longitudinal (T1) and transversal (T2) relaxation times. Most of the T1 agents used in clinical MRI are based on paramagnetic lanthanide complexes (largely Gd-based). In moving to translatable formats of reduced toxicity, greater chemical stability, longer circulation times, higher contrast, more controlled functionalisatio
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MOJOVIĆ, MILOŠ, MARKO DAKOVIĆ, MIA OMERAŠEVIĆ, et al. "THE PARAMAGNETIC PILLARED BENTONITES AS DIGESTIVE TRACT MRI CONTRAST AGENTS." International Journal of Modern Physics B 24, no. 06n07 (2010): 780–87. http://dx.doi.org/10.1142/s0217979210064411.

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The increased use of imaging techniques in diagnostic studies, such as MRI, has contributed to the development of the wide range of new materials which could be successfully used as image improving agents. However, there is a lack of such substances in the area of gastrointestinal tract MRI. Many of the traditionally popular relaxation altering agents show poor results and disadvantages provoking black bowel, side effects of diarrhea and the presence of artifacts arising from clumping. Paramagnetic species seem to be potentially suitable agents for these studies, but contrast opacification has
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Xu, Wenlong, Krishna Kattel, Ja Young Park, Yongmin Chang, Tae Jeong Kim, and Gang Ho Lee. "Paramagnetic nanoparticle T1 and T2 MRI contrast agents." Physical Chemistry Chemical Physics 14, no. 37 (2012): 12687. http://dx.doi.org/10.1039/c2cp41357d.

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Navon, G., R. Panigel, and G. Valensin. "Liposomes containing paramagnetic macromolecules as MRI contrast agents." Magnetic Resonance in Medicine 3, no. 6 (1986): 876–80. http://dx.doi.org/10.1002/mrm.1910030608.

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Lee, Soo Hong, Byung Hyo Kim, Hyon Bin Na, and Taeghwan Hyeon. "Paramagnetic inorganic nanoparticles as T1 MRI contrast agents." Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 6, no. 2 (2013): 196–209. http://dx.doi.org/10.1002/wnan.1243.

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Zeng, Leyong, Di Wu, Ruifen Zou, Tianxiang Chen, Jinchao Zhang, and Aiguo Wu. "Paramagnetic and Superparamagnetic Inorganic Nanoparticles for T1-Weighted Magnetic Resonance Imaging." Current Medicinal Chemistry 25, no. 25 (2018): 2970–86. http://dx.doi.org/10.2174/0929867324666170314124616.

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Magnetic resonance imaging (MRI) has become a promising technique in the early diagnosis of cancers, especially the application of contrast agents can further enhance the detection limit. Compared with the dark signal in “negative” contrast agents (T2), “positive” contrast agents (T1) with bright signal are more desirable for high-resolution imaging. However, the clinically used gadolinium complexes have short circulation time and the risk of nephrogenic system fibrosis. Therefore, to overcome the disadvantage of T2 agents and traditional T1 agents, it is very interesting to develop nano-scale
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Tegafaw, Tirusew, Shuwen Liu, Mohammad Yaseen Ahmad, et al. "Magnetic Nanoparticle-Based High-Performance Positive and Negative Magnetic Resonance Imaging Contrast Agents." Pharmaceutics 15, no. 6 (2023): 1745. http://dx.doi.org/10.3390/pharmaceutics15061745.

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In recent decades, magnetic nanoparticles (MNPs) have attracted considerable research interest as versatile substances for various biomedical applications, particularly as contrast agents in magnetic resonance imaging (MRI). Depending on their composition and particle size, most MNPs are either paramagnetic or superparamagnetic. The unique, advanced magnetic properties of MNPs, such as appreciable paramagnetic or strong superparamagnetic moments at room temperature, along with their large surface area, easy surface functionalization, and the ability to offer stronger contrast enhancements in M
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Pagel, Mark D. "Responsive paramagnetic chemical exchange saturation transfer MRI contrast agents." Imaging in Medicine 3, no. 4 (2011): 377–80. http://dx.doi.org/10.2217/iim.11.29.

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Dissertations / Theses on the topic "Paramagnetic MRI agents"

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Fauconnier, Theresa K. "Azapropazone and derivatized EDTA and DTPA complexes as MRI contrast agents /." *McMaster only, 1996.

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Waiter, Gordon David. "The NMR proton relaxation effectiveness of paramagnetic metal ions and their potential as MRI contrast agents." Thesis, University of Aberdeen, 1995. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU077829.

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Paramagnetic lanthanide ions have been investigated as possible MIR phantom materials and contrast agents. The aim of this study is to determine if it is possible to apply the well known Solomon-Bloembergen equations to solutions of paramagnetic lanthanide ions that have fast electron spin relaxation times, compared to Gadolinium, the most widely used ion for NMR. Studies of the relaxivity, frequency and temperature dependence, show that there is a considerable difference in those properties over the series. Chelation of the ions to EDTA and DTPA resulted in a decrease in the relaxivity which
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Peci, Taze. "Carbon nanotubes filled with continuous ferromagnetic α-Fe nanowires and surface-functionalized with paramagnetic Gd(III) : a candidate magnetic hyperthermia structure and MRI contrast agent". Thesis, Queen Mary, University of London, 2017. http://qmro.qmul.ac.uk/xmlui/handle/123456789/31862.

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The main goal of this project was the development of carbon nanotubes as a candidate for dual-functioning magnetic hyperthermia structure and magnetic resonance imaging contrast agent. This was achieved by filling carbon nanotubes with continuous ferromagnetic α-Fe nanowires and surface functionalized with paramagnetic Gd(III). Also, length control of both nanotube and nanowire was investigated. Firstly, a low vapour flow-rate and constant evaporation temperature chemical vapour deposition method based on the thermal decomposition of ferrocene was employed which achieved continuous α-Fe nanowi
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Pereira, Giovannia Araújo de Lima. "Paramagnetic systems as potential MRI contrast agents : evaluation of physical-chemical properties." Doctoral thesis, 2008. http://hdl.handle.net/10316/7442.

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Gupta, Abhishek. "Development and characterisation of advanced MRI contrast agents." Thesis, 2015. http://hdl.handle.net/1959.7/uws:51640.

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Magnetic resonance imaging (MRI) is a non-invasive imaging technique that has emerged as one of the most powerful diagnostic tools in clinical medicine. Paramagnetic contrast agents (CAs), usually Gd-chelates, are often employed during an MRI scan to achieve better image contrast between a diseased and normal tissue. They work by modulating the longitudinal and transverse relaxation times of water protons within the tissues. Most of the current commercially available CAs, which can be broadly classified as low molecular weight CAs, are small, fast reorientating molecules with restricted specif
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Blahut, Jan. "Regiospecifické deriváty cyklamu pro radiomedicinské a MRI aplikace." Master's thesis, 2013. http://www.nusl.cz/ntk/nusl-321916.

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Cyclam (1,4,8,11-tetraazacyclotetradecane) derivatives are widely used for various purposes. In a medicine they are applied as ligands for radiometals applied as diagnostic or therapeutic agents against tumours, hypoxic brain tissues etc. In this thesis a new method for asymmetric cyclam derivati- ves preparation was developed. New cyclam derivatives with trifluoroethyl groups were prepared too. Paramagnetic metal complexes with these fluori- nated ligands can be used as contrast agents for 19 F-MRI. Keywords: Cyclam; Non-symmetric protection; Contrast agents; Trifluoroethylamines; Paramagneti
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Book chapters on the topic "Paramagnetic MRI agents"

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Laurent, Sophie, Céline Henoumont, Dimitri Stanicki, et al. "Paramagnetic Gadolinium Complexes." In MRI Contrast Agents. Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-2529-7_4.

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Terreno, Enzo, Daniela Delli Castelli, and Silvio Aime. "Paramagnetic CEST MRI Contrast Agents." In The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging. John Wiley & Sons, Ltd, 2013. http://dx.doi.org/10.1002/9781118503652.ch9.

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Sherry, A. Dean, and Mark Woods. "Lanthanide-Based Paramagnetic Chemical Exchange Saturation Transfer (paraCEST) Agents for MRI." In Lanthanide and Other Transition Metal Ion Complexes and Nanoparticles in Magnetic Resonance Imaging. CRC Press, 2024. http://dx.doi.org/10.1201/9781003374688-7.

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Zanella, F. E., G. Friedmann, and W. Heindel. "Value of Paramagnetic Contrast Agents in the Evaluation of the Craniocervical Junction by MRI." In Imaging of Brain Metabolism Spine and Cord Interventional Neuroradiology Free Communications. Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74337-5_27.

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Nguyen, Kim-Lien, and J. Paul Finn. "MRI contrast agents." In The EACVI Textbook of Cardiovascular Magnetic Resonance, edited by Massimo Lombardi, Sven Plein, Steffen Petersen, et al. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198779735.003.0011.

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Pharmacologic agents used in the context of a cardiovascular magnetic resonance imaging examination can be divided into three main groups: contrast agents, stress-testing agents (dobutamine, adenosine, regadenoson, dipyridamole), and agents used for treatment of hypersensitivity reactions. The safety of stress agents will be elaborated in the chapter on ischaemic heart disease. This chapter will focus on contrast agents and briefly touch upon medications used in the setting of hypersensitivity reactions. Contrast agents are used to further augment tissue contrast and have become an integral co
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Bertini, Ivano, Claudio Luchinat, Giacomo Parigi, and Enrico Ravera. "Relaxometry and contrast agents for MRI." In Solution NMR of Paramagnetic Molecules. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-444-63436-8.00010-7.

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Singh Gehlot, Praveen, and Arvind Kumar. "Iron-Based Ionic Liquids for Magnetic Resonance Imaging Application." In Industrial Applications of Ionic Liquids [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.107948.

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In the biomedical treatment, identification of diseases and their diagnosis are running with help of many biomedical techniques including imaging such as magnetic resonance imaging (MRI). MRI technique requires an identification of targeted cell or lesion area which can be achieved by contrast agent. For clinical use, T1 positive MRI contrast agents and T2 negative MRI contrast agents are being used. However, these contrast agents have several drawbacks such as toxic effect of metal centre, poor resolution, weak contrast, low intensity image and short signal for long-term in vivo measurement.
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Aime, Silvio, Zsolt Baranyai, Eliana Gianolio, and Terreno Enzo. "Paramagnetic Contrast Agents." In Molecular and Cellular MR Imaging. CRC Press, 2007. http://dx.doi.org/10.1201/9781420004090-3.

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Gianolio, Eliana, Silvio Aime, Enzo Terreno, and Zsolt Baranyai. "Paramagnetic Contrast Agents." In Molecular and Cellular MR Imaging. CRC Press, 2007. http://dx.doi.org/10.1201/9781420004090.ch3.

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Conference papers on the topic "Paramagnetic MRI agents"

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Fioravanti, Dr Giulia. "Revisiting the Influence of Metal Impurities and Structural Defects on the Intrinsic Paramagnetism of Graphene Oxide (Go)." In 6th World Conference on Chemistry and Chemical Engineering and 6th World Conference on Advanced Materials, Nanoscience and Nanotechnology. Eurasia Conferences, 2024. https://doi.org/10.62422/978-81-974314-2-5-004.

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GO-based materials have recently attracted substantial attention in the biomedical field as effective contrast agents (CAs) in Nuclear Magnetic Resonance Imaging (NMRI). This study focuses on the importance of understanding the interplay between metal contaminants and structural defects on the paramagnetism of GO (Fig. 1). Figure 1. (a) A simplified diagram of the GO structure, containing the different oxygenated groups (hydroxyl, epoxy, and carboxyl), defects (holes, dangling bonds), and metallic contaminants, and (b) MRI of GO water solutions: T1 and T2 coloured maps, adapted from [1]. A com
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Carvlin, Mark J., Perry F. Renshaw, Peter Arger, et al. "Superparamagnetic And Paramagnetic MRI Contrast Agents: Application Of Rapid Magnetic Resonance Imaging To Assess Renal Function." In Medical Imaging II, edited by Roger H. Schneider and Samuel J. Dwyer III. SPIE, 1988. http://dx.doi.org/10.1117/12.968610.

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Liang, Haipeng, Wanli Zuo, Dimitri Kessler, Tristan Barrett, and Zion Tsz Ho Tse. "MRI-Guided Robotic Prostate Biopsy." In THE HAMLYN SYMPOSIUM ON MEDICAL ROBOTICS. The Hamlyn Centre, Imperial College London London, UK, 2023. http://dx.doi.org/10.31256/hsmr2023.6.

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Prostate cancer is one of the most common malignancies and the second leading cause of cancer death in men [1]. Approximately 52,300 new cases of prostate cancer are detected in the UK every year, that’s more than 140 every day. Magnetic resonance imaging (MRI) has been widely used in the diagnosis of prostate cancer, as it can offer high-resolution tissue imaging at arbitrary orientations and monitor therapeutic agents, surgical tools, and tissue properties. Therefore, a robot - under the guidance of MRI - can target the tumor regions with high accuracy to obtain the biopsy samples for diagno
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DeLeo, Michael J., Matthew J. Gounis, Ajay K. Wakhloo, and Alexei A. Bogdanov. "Validation of Di-5-HT-Gd-DTPA, an Enzyme-Specific MR Contrast Agent for Myeloperoxidase, in the Rabbit Elastase Model of Cerebrovascular Aneurysm." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-206346.

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Characterization of molecular imaging probes in multiple animal models of disease is essential to increase their diagnostic potential. For example, we recently demonstrated visualization of active inflammation in a rabbit model saccular aneurysm using clinical field strength MRI and the paramagnetic MR contrast agent di-5-HT-GdDTPA, which has been shown in vitro to be sensitive and specific for the enzyme myeloperoxidase (MPO). While the use of transgenic mice (MPO−/−) has demonstrated specificity of di-5-HT-GdDTPA for MPO in a model of myocardial infarction [1], MPO-deficient rabbits are not
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