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Journal articles on the topic 'Paraseptal Emphysema'

Author: Grafiati
Published: 4 June 2025
Last updated: 1 August 2025

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1

Mafisah, Saidah, Yani Jane Sugiri, Teguh Rahayu Sartono, and Liana Karliasari. "Young Women With Infected Bronchiectasis and Paraseptal Emphysema." Malang Respiratory Journal 7, no. 1 (2025): 11–17. https://doi.org/10.21776/ub.mrj.2025.007.01.03.

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Introduction: Bronchiectasis is defined as an abnormal dilation of the bronchi, usually as a result of chronic airway inflammation and/or infection. Bronchiectasis with non-mycobacterial tuberculosis infection is more common in women. Paraseptal emphysema formed around the pleura or septa in the upper lobe, caused by repeated infections, smoking, or deficiency of the alpha 1 antitrypsin enzyme. Emphysema is more common in men with a history of smoking. Case: A 22 year-old female came with chief complaint of chronic cough. No smoking history. Patient had a history of repeated hospitalizations d
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2

Najafi, Atabak, Farahnaz Fallahian, Arezoo Ahmadi, and Khadijeh Bakhtavar. "Alveolar air leak and paraseptal emphysema in severe COVID-19 disease." Journal of Mechanical Ventilation 2, no. 4 (2021): 114–23. https://doi.org/10.53097/JMV.10034.

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3

Cabanne, Eglantine, and Marie-Pierre Revel. "Post–COVID-19 Vanishing Paraseptal Emphysema." Radiology 299, no. 2 (2021): E249. http://dx.doi.org/10.1148/radiol.2021210339.

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4

Zompatori, Maurizio, Maria Rita Rimondi, Giampaolo Gavelli, and Romeo Canini. "Paraseptal Emphysema Mimicking Unilateral Lymphangitic Carcinomatosis." Journal of Computer Assisted Tomography 17, no. 5 (1993): 810–12. http://dx.doi.org/10.1097/00004728-199309000-00027.

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5

Sheykh, Zh V., E. V. Nikolaev, I. E. Tyurin, et al. "CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH EMPHYSEMA AND GIANT BULLAE IN A SMOKER." Journal of radiology and nuclear medicine 99, no. 4 (2018): 204–10. http://dx.doi.org/10.20862/0042-4676-2018-99-4-204-210.

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Radiation diagnosis in evaluating chronic obstructive pulmonary disease (COPD) is used to distinguish clinically similar diseases and to identify concomitant pathological changes. Highresolution computed tomography (HRCT) is employed for detailed analysis of the status of the lung. HRCT can visualize primarily centrilobular, panlobular, paraseptal, and bullous emphysema and bronchiectases, is of great importance in the anatomical characteristics of the disease and in the identification of the phenotype of COPD.The paper describes a clinical case of COPD with bullous emphysema in a 60-year-old
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6

Najafi, Atabak, Farahnaz Fallahian, Arezoo Ahmadi, and Khadijeh Bakhtavar. "Alveolar air leak and paraseptal emphysema in severe COVID-19 disease." Journal of Mechanical Ventilation 2, no. 4 (2021): 114–23. http://dx.doi.org/10.53097/jmv.10034.

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Background Corona virus 2019 (COVID-19) pandemic spread in the world as a great medical crisis. Its pathophysiology, manifestations, complications, and management are not completely defined, yet. In this study frequency of alveolar air leak in critically ill COVID-19 subjects is explored. Methods A total of 820 critically ill COVID-19 subjects who admitted with respiratory insufficiency to ICUs of Sina University Hospital from March 2020 to June 2021 were included. All their chest x ray (CXR) and Computed tomography (CT) of chest were reviewed. All alveolar air leak episodes (pneumothorax, pne
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7

FILIPPENKO, Y., Zh AMANKULOV, Zh ZHOLDYBAY, Zh ZHAKENOVA, A. PANINA, and S. KASENOVA. "COMPUTED TOMOGRAPHY FEATURES OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE ASSOCIATED WITH LUNG CANCER." Oncologia i radiologia Kazakhstana 63, no. 1 (2022): 36–40. http://dx.doi.org/10.52532/2663-4864-2022-1-63-36-40.

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Relevance: Chronic obstructive pulmonary disease (COPD) associated with lung can-cer is common in smoking patients. Computed
 tomography (CT) is vital in detecting lung cancer, assessing regional lung parenchymal destruction, and airway remodeling in COPD.
 The study aimed to determine the CT features of COPD associated with lung cancer.
 Methods: This retrospective study included chest CT exams of 56 patients over the age of 40 with a smoking history of 10 years and
 more and with suspected COPD. 46.43% of patients had CT signs of lung cancer associated with COPD.
 Re
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8

Filippenko, Y., Zh Amankulov, Zh Zholdybay, Zh Zhakenova, A. Panina, and S. Kasenova. "COMPUTED TOMOGRAPHY FEATURES OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE ASSOCIATED WITH LUNG CANCER." Oncologia i radiologia Kazakhstana 63, no. 1 (2022): 36–40. http://dx.doi.org/10.52532/2521-6414-2022-1-63-36-40.

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Relevance: Chronic obstructive pulmonary disease (COPD) associated with lung cancer is common in smoking patients. Computed tomography (CT) is vital in detecting lung cancer, assessing regional lung parenchymal destruction, and airway remodeling in COPD.
 ДИАГНОСТИКА
 40 Онкология и радиология Казахстана, №1 (63) 2022
 The study aimed to determine the CT features of COPD associated with lung cancer.
 Methods: This retrospective study included chest CT exams of 56 patients over the age of 40, with a smoking history of 10 years and more and
 with suspected COPD. 46.43% o
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9

Sreeja, Ummadi. "AUTOMATED CLASSIFICATION OF EMPHYSEMA USING CONVOLUTIONAL NEURAL NETWORKS." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 08, no. 06 (2024): 1–5. http://dx.doi.org/10.55041/ijsrem35769.

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The analysis of CT scans for emphysema diagnosis can be formulated as a computer vision problem, where predefined patterns are used to automatically classify the images. This paper investigates a method for classifying emphysema subtypes in High-Resolution Computed Tomography (HRCT) scans using convolutional neural networks (CNNs). This classification is crucial for accurate diagnosis and management of emphysema, a chronic lung disease causing shortness of breath. Our approach leverages transfer learning to extract informative features from HRCT images labeled as centrilobular (CLE), parasepta
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10

Louza, Guilherme Felix, Gláucia Zanetti, and Edson Marchiori. "Aspergilloma in Honeycomb Cysts and Paraseptal Emphysema: An Unusual Association." Archivos de Bronconeumología 54, no. 2 (2018): 110–11. http://dx.doi.org/10.1016/j.arbres.2017.06.027.

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11

Copeland, Carla R., Hrudaya Nath, Nina L. J. Terry, et al. "Paratracheal Paraseptal Emphysema and Expiratory Central Airway Collapse in Smokers." Annals of the American Thoracic Society 15, no. 4 (2018): 479–84. http://dx.doi.org/10.1513/annalsats.201709-713oc.

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12

Louza, Guilherme Felix, Gláucia Zanetti, and Edson Marchiori. "Aspergilloma in Honeycomb Cysts and Paraseptal Emphysema: An Unusual Association." Archivos de Bronconeumología (English Edition) 54, no. 2 (2018): 110–11. http://dx.doi.org/10.1016/j.arbr.2017.06.010.

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13

Bendsten, Dan, and Takkin Lo. "Unusual paraseptal emphysema as the primary changes in computerized tomography scan of a COVID-19 patient. Case report." Journal of Mechanical Ventilation 1, no. 1 (2020): 14–18. http://dx.doi.org/10.53097/jmv.10004.

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Covid-19 pandemic has infected more than 20 million people worldwide and claimed more than 750,000 lives so far. Given that this disease is new, the long-term lung effects for survivors especially of severe cases are unknown. Most radiographic changes compared to those commonly seen in Acute Respiratory Distress Syndrome (ARDS), manifested as groundglass opacities or diffuse interstitial/alveolar changes. We present a case of severe acute respiratory failure secondary to COVID-19 requiring prolonged mechanical ventilation and hospitalization with subsequent lung damage and unusual formation of
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14

Griva, N. A., P. V. Gavrilov, I. A. Nikitina, L. D. Kiryukhina, A. N. Narkevich, and E. G. Sokolovich. "Impact of Emphysema Subtypes and Volume on Lung Ventilation and Gas Exchange Functions as Evidenced by Computed Tomography." Journal of radiology and nuclear medicine 102, no. 6 (2022): 349–58. http://dx.doi.org/10.20862/0042-4676-2021-102-6-349-358.

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Objective: to characterize the relationship between the subtype and volume of pulmonary emphysema on the indicators of lung ventilation and gas exchange functions. Material and methods. The data of radiation and functional studies were analyzed in 50 patients. The inclusion criteria were chronic obstructive pulmonary disease and emphysema, which had been diagnosed by computed tomography (CT) and confirmed by two radiologists; comprehensive pulmonary function studies, including spirometry and body plethysmography, were performed; diffusion capacity was measured using a single-breath method, inv
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15

Portillo, Karina, and Josep Morera. "Combined Pulmonary Fibrosis and Emphysema Syndrome: A New Phenotype within the Spectrum of Smoking-Related Interstitial Lung Disease." Pulmonary Medicine 2012 (2012): 1–8. http://dx.doi.org/10.1155/2012/867870.

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Combined pulmonary fibrosis and emphysema (CPFE) is a recently defined syndrome, in which centrilobular and/or paraseptal emphysemas in upper lung zones coexist with pulmonary fibrosis in lower lobes in individuals. These patients have a characteristic lung function profile, with unexpected subnormal dynamic and static lung volumes, contrasting with a significant reduction of carbon monoxide transfer (DLco) and exercise hypoxemia. Pulmonary hypertension is highly prevalent in CPFE and is the leading determinant of death. Tobacco smoking has been proposed as the main factor in its etiology, tho
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16

Tanabe, Naoya, and Toyohiro Hirai. "Recent advances in airway imaging using micro-computed tomography and computed tomography for chronic obstructive pulmonary disease." Korean Journal of Internal Medicine 36, no. 6 (2021): 1294–304. http://dx.doi.org/10.3904/kjim.2021.124.

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Chronic obstructive pulmonary disease (COPD) is a complex lung disease characterized by a combination of airway disease and emphysema. Emphysema is classified as centrilobular emphysema (CLE), paraseptal emphysema (PSE), or panlobular emphysema (PLE), and airway disease extends from the respiratory, terminal, and preterminal bronchioles to the central segmental airways. Although clinical computed tomography (CT) cannot be used to visualize the small airways, micro-CT has shown that terminal bronchiole disease is more severe in CLE than in PSE and PLE, and micro-CT findings suggest that the los
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17

Sloots, Joanne M., and Marieke L. Duiverman. "Pneumothorax in patients with COPD and emphysema receiving home chronic non-invasive ventilation: is it the emphysema phenotype or ventilator setting?" BMJ Case Reports 16, no. 1 (2023): e253186. http://dx.doi.org/10.1136/bcr-2022-253186.

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We describe three patients with chronic obstructive pulmonary disease (COPD) and emphysema who developed a pneumothorax while receiving chronic home non-invasive ventilation (NIV). These cases raise the question whether the high alveolar pressures given by NIV may have contributed to the development of their pneumothorax by barotrauma. Pneumothorax in patients with COPD receiving NIV is uncommon, the pressures in our patients with COPD who developed pneumothorax were not extremely high and time to development of pneumothorax was relatively long after the initiation of NIV. Further, in our pati
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18

López, A. M., E. Caeiro, M. Medic, and M. I. Garzón. "Evolución de paciente trasplantado pulmonar con hallazgo de autopsia." Revista de la Facultad de Ciencias Médicas de Córdoba 68, no. 2 (2011): 72–78. http://dx.doi.org/10.31053/1853.0605.v68.n2.21540.

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A 56-year-old man, he was admitted to this institution due to deterioration of the general state and depression of the sensory system.Among its antecedents, we can mention: obesity, facial basocellular carcinoma, severe smoking (32p/y), vasculitis due to hypersensitivity with Ig A deposits (skin biopsy), very severe COPD (centroacinar emphysema and diffuse paraseptal), with functional dyspnea grade III - IV, OCD (chronic home oxygen therapy) since 1995, unilateral right lung transplant in 1999, with 13 days postoperative. Initial management with cyclosporine, azathioprine and meprednisone.
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19

Tanabe, Naoya, Dragoş M. Vasilescu, Cameron J. Hague, et al. "Pathological Comparisons of Paraseptal and Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease." American Journal of Respiratory and Critical Care Medicine 202, no. 6 (2020): 803–11. http://dx.doi.org/10.1164/rccm.201912-2327oc.

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20

Taskiran, Naz P., Grant T. Hiura, Xuzhe Zhang, et al. "Mapping Alveolar Oxygen Partial Pressure in COPD Using Hyperpolarized Helium-3: The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study." Tomography 8, no. 5 (2022): 2268–84. http://dx.doi.org/10.3390/tomography8050190.

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Chronic obstructive pulmonary disease (COPD) and emphysema are characterized by functional and structural damage which increases the spaces for gaseous diffusion and impairs oxygen exchange. Here we explore the potential for hyperpolarized (HP) 3He MRI to characterize lung structure and function in a large-scale population-based study. Participants (n = 54) from the Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study, a nested case-control study of COPD among participants with 10+ packyears underwent HP 3He MRI measuring pAO2, apparent diffusion coefficient (ADC), and ventilation. HP MRI m
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21

Wu, Yanan, Shouliang Qi, Yu Sun, Shuyue Xia, Yudong Yao, and Wei Qian. "A vision transformer for emphysema classification using CT images." Physics in Medicine & Biology 66, no. 24 (2021): 245016. http://dx.doi.org/10.1088/1361-6560/ac3dc8.

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Abstract Objective. Emphysema is characterized by the destruction and permanent enlargement of the alveoli in the lung. According to visual CT appearance, emphysema can be divided into three subtypes: centrilobular emphysema (CLE), panlobular emphysema (PLE), and paraseptal emphysema (PSE). Automating emphysema classification can help precisely determine the patterns of lung destruction and provide a quantitative evaluation. Approach. We propose a vision transformer (ViT) model to classify the emphysema subtypes via CT images. First, large patches (61 × 61) are cropped from CT images which con
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Araki, Tetsuro, Mizuki Nishino, Oscar E. Zazueta, et al. "Paraseptal emphysema: Prevalence and distribution on CT and association with interstitial lung abnormalities." European Journal of Radiology 84, no. 7 (2015): 1413–18. http://dx.doi.org/10.1016/j.ejrad.2015.03.010.

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23

Diaz, Alejandro A. "Paraseptal Emphysema: From the Periphery of the Lobule to the Center of the Stage." American Journal of Respiratory and Critical Care Medicine 202, no. 6 (2020): 783–84. http://dx.doi.org/10.1164/rccm.202006-2138ed.

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24

Almeida, Renata Rocha de, Gláucia Zanetti, Arthur Soares Souza Jr., et al. "Cocaine-induced pulmonary changes: HRCT findings." Jornal Brasileiro de Pneumologia 41, no. 4 (2015): 323–30. http://dx.doi.org/10.1590/s1806-37132015000000025.

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AbstractObjective: To evaluate HRCT scans of the chest in 22 patients with cocaine-induced pulmonary disease.Methods: We included patients between 19 and 52 years of age. The HRCT scans were evaluated by two radiologists independently, discordant results being resolved by consensus. The inclusion criterion was an HRCT scan showing abnormalities that were temporally related to cocaine use, with no other apparent causal factors.Results:In 8 patients (36.4%), the clinical and tomographic findings were consistent with "crack lung", those cases being studied separately. The major HRCT findings in t
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D., Pragati Rao, Aruna Talatam, Chakradhar B., Bhargavi K., and Bhagyaraj A. "High resolution computed tomography in chronic obstructive pulmonary disease." International Journal of Advances in Medicine 5, no. 5 (2018): 1222. http://dx.doi.org/10.18203/2349-3933.ijam20183898.

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Background: Chronic obstructive pulmonary disease (COPD) is a common preventable and treatable disease characterised by persistent respiratory symptoms and airflow limitation with varied presentations (bronchitis and emphysema). High resolution computed tomography (HRCT) plays an important role in identifying the various morphologies thereby reducing morbidity and mortality. The aim of the present study was to evaluate the role of high resolution computed tomography in COPD patients. The Objectives of the present study was to differentiate emphysema predominant, airway predominant and mixed ph
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26

Haloi, Prajnananda, Rahul Biswas, and Ananta K. Bora. "Anesthetic management of a case of a lip mass with paraseptal emphysema and multiple bilateral giant bullae for surgical resection under mental nerve block." Saudi Journal of Anaesthesia 18, no. 3 (2024): 442–44. http://dx.doi.org/10.4103/sja.sja_43_24.

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Anesthesia in patients with emphysematous giant bulla undergoing non-thoracic surgery is challenging and can cause serious complications. We report a successful case of lip mass resection in a 65-year-old male with paraseptal emphysema and giant bullae under regional anesthesia using a mental nerve block. The patient presented with a slow-growing ulcerative mass on his lower lip and had a history of non-compliant COPD management. An excisional biopsy was planned. Preoperative workup revealed extensive lung pathology with giant bullae. General anesthesia with positive pressure ventilation in pa
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Patel, Ishan, Sarah Medrek, Michael Reyes, and Brannon Raney. "December 2023 Pulmonary Case of the Month: A Budding Pneumonia." Southwest Journal of Pulmonary, Critical Care & Sleep 27, no. 6 (2023): 62–66. http://dx.doi.org/10.13175/swjpccs048-23.

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No abstract available. Manuscript truncated after 150 words. History of Present Illness A 70-year-old man with a history of seropositive rheumatoid arthritis previously well controlled on hydroxychloroquine, methotrexate, and adalimumab was admitted to the hospital with 3 weeks of progressively worsening fatigue, night sweats, chills, and malaise. He did not describe new or worsening cough, shortness of breath, or sputum production. On the day of admission, he had intense nausea and vomiting. PMH, SH, and FH Prior to this admission, he was followed in Pulmonary Clinic for asymptomatic mild bas
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28

Koesoemoprodjo, Winariani, and Daniel Maranatha. "Level of serum IL-33 and paraseptal emphysema in clove cigarette smoker with spontaneous pneumothorax: A case report." Respiratory Medicine Case Reports 30 (2020): 101133. http://dx.doi.org/10.1016/j.rmcr.2020.101133.

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29

Ramachandran, Rajoo, Jeffrey Ralph, Rajeev Pulimi, Logesh Rajamani, Prabhu Radhan, and Kumaresh Athiyappan. "Revisiting Cystic Lung Disease - A Review on Diagnostic Approach in High Resolution Computed Tomography Thorax." Journal of Evolution of Medical and Dental Sciences 10, no. 19 (2021): 1435–43. http://dx.doi.org/10.14260/jemds/2021/302.

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The differential diagnosis of the cystic lung disease is extensive, ranging from an isolated incidental lung cyst to multiple diffuse lung cysts with other varied associated lung abnormalities. High resolution computed tomography (HRCT) thorax is the imaging modality of choice in the evaluation of these diseases, by improving the characterisation of the lung cysts (number, size, shape, distribution, wall thickness and regularity), and associated pulmonary and extrapulmonary abnormalities (like ground glass densities, nodules, interstitial fibrosis, mediastinal lymphadenopathy). After different
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Cukier, Alberto, Rafael Stelmach, Jorge Issamu Kavakama, Mário Terra Filho, and Francisco Vargas. "Persistent asthma in adults: comparison of high resolution computed tomography of the lungs after one year of follow-up." Revista do Hospital das Clínicas 56, no. 3 (2001): 63–68. http://dx.doi.org/10.1590/s0041-87812001000300001.

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OBJECTIVE: The aims of this study were to evaluate the role of high resolution computed tomography of the torax in detecting abnormalities in chronic asthmatic patients and to determine the behavior of these lesions after at least one year. METHOD: Fourteen persistent asthmatic patients with a mean forced expiratory volume in 1-second that was 63% of predicted and a mean forced expiratory volume in 1-second /forced vital capacity of 60% had two high resolution computed tomographys separated by an interval of at least one year. RESULTS: All 14 patients had abnormalities on both scans. The most
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Bendsten, Dan, and Takkin Lo. "Unusual Para-septal Emphysema As The Primary Changes in Computerized Tomography Scan of a COVID-19 Patient." Journal of Mechanical Ventilation 1, no. 1 (2020): 14–18. https://doi.org/10.5281/zenodo.3986559.

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32

Jang, G., F. Blanc-Jouvan, M. Coulomb, and C. Brambilla. "Emphysème paraseptal et pseudo syndrome interstitiel." La Revue de Médecine Interne 14, no. 5 (1993): 350–51. http://dx.doi.org/10.1016/s0248-8663(05)81313-x.

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Ünal, Esranur Üna, Seray Külcü Çakmak, and Ahu Yorulmaz. "The red half-moon nail sign in a COVID-19 patient." Our Dermatology Online 13, no. 2 (2022): 223–24. http://dx.doi.org/10.7241/ourd.20222.29.

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Sir, Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic. Several cutaneous manifestations associated with COVID-19 have been reported, including chilblains or chilblain-like lesions, erythematous rash, viral exanthem, urticaria, livedo reticularis, acral ischemia, palpable purpura, and erythema multiforme. These were thought to be useful in the early diagnosis and triage of COVID-19 patients and their risk stratification [1]. However, there are limited reports on the nail manifestations of COVID-19,
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Marchiori1, Edson, Bruno Hochhegger2, and Gláucia Zanetti1. "Paraseptal emphysema." Jornal Brasileiro de Pneumologia, November 21, 2023, e20230340. http://dx.doi.org/10.36416/1806-3756/e20230340.

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Tung, Nguyen Thanh, Shu-Chuan Ho, Yueh-Hsun Lu, et al. "Association Between Air Pollution and Lung Lobar Emphysema in COPD." Frontiers in Medicine 8 (September 21, 2021). http://dx.doi.org/10.3389/fmed.2021.705792.

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The development of emphysema has been linked to air pollution; however, the association of air pollution with the extent of lobar emphysema remains unclear. This study examined the association of particulate matter <2.5 μm in aerodynamic diameters (PM2.5) (≤2.5 μm), nitrogen dioxide (NO2), and ozone (O3) level of exposure with the presence of emphysema in 86 patients with chronic obstructive pulmonary disease (COPD). Exposure to the air pollution estimated using the land-use regression model was associated with lung function, BODE (a body mass index, degree of obstruction, dyspnea sever
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Zhou, Yun, Zhiyi He, Jing Bai, and Xiaoning Zhong. "Respiratory bronchiolitis‐associated interstitial lung disease with obvious paraseptal emphysema." Respirology Case Reports 4, no. 6 (2016). http://dx.doi.org/10.1002/rcr2.198.

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Xie, Weiyi, Colin Jacobs, Jean-Paul Charbonnier, Dirk Jan Slebos, and Bram van Ginneken. "Emphysema subtyping on thoracic computed tomography scans using deep neural networks." Scientific Reports 13, no. 1 (2023). http://dx.doi.org/10.1038/s41598-023-40116-6.

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AbstractAccurate identification of emphysema subtypes and severity is crucial for effective management of COPD and the study of disease heterogeneity. Manual analysis of emphysema subtypes and severity is laborious and subjective. To address this challenge, we present a deep learning-based approach for automating the Fleischner Society’s visual score system for emphysema subtyping and severity analysis. We trained and evaluated our algorithm using 9650 subjects from the COPDGene study. Our algorithm achieved the predictive accuracy at 52%, outperforming a previously published method’s accuracy
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Klont, Frank, Peter Horvatovich, Russell P. Bowler, et al. "Plasma sRAGE levels strongly associate with centrilobular emphysema assessed by HRCT scans." Respiratory Research 23, no. 1 (2022). http://dx.doi.org/10.1186/s12931-022-01934-w.

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Abstract Background There is a strong need for biomarkers to better characterize individuals with COPD and to take into account the heterogeneity of COPD. The blood protein sRAGE has been put forward as promising biomarker for COPD in general and emphysema in particular. Here, we measured plasma sRAGE levels using quantitative LC–MS and assessed whether the plasma sRAGE levels associate with (changes in) lung function, radiological emphysema parameters, and radiological subtypes of emphysema. Methods Three hundred and twenty-four COPD patients (mean FEV1: 63%predicted) and 185 healthy controls
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Cortese, Rosaria, Salvatore Savasta, Silvia Di Stasi, et al. "Lung disease recalling paraseptal emphysema in a patient with Goltz syndrome." Multidisciplinary Respiratory Medicine 11 (September 13, 2016). http://dx.doi.org/10.4081/mrm.2016.327.

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Background: Goltz syndrome is a rare, genetic disorder mainly occurring in female patients. Case presentation: The case presented here is, to the best of our knowledge, the first description of the occurrence of lung parenchymal alterations in a young female patient affected by Goltz syndrome. Although pulmonary involvement is not known in patients affected by X-linked Goltz syndrome, the case here described is related to the even rarer autosomal form of the disease, as in this case. It is thus conceivable that in such different genetic setting the involvement of lung parenchyma may be unveile
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Cortese, Rosaria, Salvatore Savasta, Silvia Di Stasi, et al. "Lung disease recalling paraseptal emphysema in a patient with Goltz syndrome." Multidisciplinary Respiratory Medicine 11, no. 1 (2016). http://dx.doi.org/10.1186/s40248-016-0069-9.

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Shiraishi, Yusuke, Takafumi Shimada, Naoya Tanabe, et al. "The prevalence and physiological impacts of centrilobular and paraseptal emphysema on CT in smokers with Preserved Ratio Impaired Spirometry." ERJ Open Research, May 26, 2022, 00063–2022. http://dx.doi.org/10.1183/23120541.00063-2022.

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Centrilobular emphysema (CLE) and paraseptal emphysema (PSE) are observed in smokers with Preserved Ratio Impaired Spirometry (PRISm, defined as the ratio of forced expiratory volume in 1 s (FEV1) to forced vital capacity (FVC)≥0.7 and FEV1<80%), but their prevalence and physiological impacts remain unestablished. This multicenter study aimed to investigate its prevalence and to test whether emphysema subtypes are differently associated with physiological impairments in smokers with PRISm.Both never and ever smokers aged at ≥40 years who underwent CT for lung cancer screening and spirometry
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42

Doğan, Emrah, Utku Tapan, Özge Oral Tapan, Fatih Alaşan, Sabri Serhan Olcay, and Tuğba Çınar Olcay. "A case of B.1.1.7 SARS-CoV-2 UK strain with an atypical radiological presentation." Monaldi Archives for Chest Disease, June 7, 2021. http://dx.doi.org/10.4081/monaldi.2021.1840.

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The new UK strain was first described in December 2020. It was seen for the first time in Turkey in February 2021. It is not yet known whether the new strain has different CT patterns compared to the classical type. We present a 68-years-old male patient with an atypical CT presentation in which GGOs are gathered around the areas of paraseptal emphysema accompanied by CT and clinical findings. This involvement is an unexpected pattern because of the atypical distribution of the GGO.
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43

Marchiori, Edson, Rosana Souza Rodrigues, and Miriam Menna Barreto. "Exuberant Paraseptal Emphysema Associated With Pulmonary Alveolar Microlithiasis: 12 Years of Evolution." Archivos de Bronconeumología, June 2021. http://dx.doi.org/10.1016/j.arbres.2021.06.012.

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44

Inoue, Chihiro, Atsuko Amata, Tatsuya Chonan, Yoshinori Kawabata, Yosuke Matsuno, and Takashi Suzuki. "Paraseptal Emphysema in Indium Lung: Tracing the Pathological Footprints of Chronic Exposure." Tohoku Journal of Experimental Medicine, 2024. http://dx.doi.org/10.1620/tjem.2024.j017.

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45

Damiani Ferretti, Margherita, Maria Rita Rimondi, and Maurizio Zompatori. "An unusual association of emphysema and interstitial disease." Journal of Medical Imaging and Interventional Radiology 12, no. 1 (2025). https://doi.org/10.1007/s44326-024-00047-6.

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Abstract Many lung diseases are smoking-related. Among them, tumors, centrilobular and bullous paraseptal emphysema and fibrosing interstitial lung diseases (fibrosing ILDs), especially those with a usual interstitial pneumonia (UIP) pattern, are the most important entities. One may think it is easy to recognize emphysema on a chest X-ray (CXR) or on a high-resolution computed tomography (HRCT). However, the combination of emphysema and fibrosis can be found in many interstitial lung diseases, characterized by different radiologic features, course and prognosis. Moreover, quite frequently more
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Mochizuki, Fumi, Naoya Tanabe, Takafumi Shimada, et al. "Centrilobular emphysema and airway dysanapsis: Factors associated with low respiratory function in younger smokers." ERJ Open Research, February 1, 2024, 00695–2023. http://dx.doi.org/10.1183/23120541.00695-2023.

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BackgroundLow respiratory function in young adulthood is one of the important factors in the trajectory leading to the future development of chronic obstructive pulmonary disease (COPD), but its morphologic characteristics are not well characterised.MethodsWe retrospectively enrolled 172 subjects aged 40–49 years with ≥10 pack-years smoking history who underwent lung cancer screening by computed tomography (CT) and spirometry at two Japanese hospitals. Emphysema was visually assessed according to the Fleischner Society guidelines and classified into two types: centrilobular emphysema (CLE) and
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Yang, Xiaofei, Monique D. Dorrius, Wenzhen Jiang, et al. "Association between visual emphysema and lung nodules on low-dose CT scan in a Chinese Lung Cancer Screening Program (Nelcin-B3)." European Radiology, June 9, 2022. http://dx.doi.org/10.1007/s00330-022-08884-3.

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Abstract Objectives This study aimed to evaluate the association between visual emphysema and the presence of lung nodules, and Lung-RADS category with low-dose CT (LDCT). Methods Baseline LDCT scans of 1162 participants from a lung cancer screening study (Nelcin-B3) performed in a Chinese general population were included. The presence, subtypes, and severity of emphysema (at least trace) were visually assessed by one radiologist. The presence, size, and classification of non-calcified lung nodules (≥ 30 mm3) and Lung-RADS category were independently assessed by another two radiologists. Multi
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Ma, Aiping, Renliang Huang, Jiaxi Guo, et al. "Association of combined pulmonary fibrosis and emphysema in rheumatoid arthritis with high titer of rheumatoid factor and autoimmunity to the lung." Frontiers in Immunology 16 (February 5, 2025). https://doi.org/10.3389/fimmu.2025.1514552.

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BackgroundCombined pulmonary fibrosis and emphysema (CPFE) commonly coexists with connective tissue diseases (CTD), such as rheumatoid arthritis (RA). However, the risk factors contributing to the development of CTD-CPFE remain largely unidentified. This study aimed to characterize CPFE using a large cohort of consecutive RA patients and to elucidate potential risk factors associated with RA- CPFE development.MethodsA total of 976 RA patients were enrolled in this cross-sectional study to characterize RA-CPFE. Multiple logistic analyses were conducted to identify potential risk factors for RA-
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Touge, Hirokazu, Haruki Masui, Mitsuhiro Yamamoto, et al. "Small‐Cell Lung Carcinoma Associated With Cystic Airspaces: A Case Report." Case Reports in Medicine 2025, no. 1 (2025). https://doi.org/10.1155/carm/5314337.

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Small‐cell lung carcinoma (SCLC) associated with cystic airspaces is rare. We describe the case of a 68‐year‐old man who was referred to our hospital because of a cystic lesion detected on chest radiography. Initial computed tomography revealed a small nodule abutting the cystic airspace due to paraseptal emphysema in the right lower lobe. Histopathological examination of lymphadenopathy indicated SCLC. Postchemotherapy, recurrence appeared as a thick‐walled cystic airspace with an exophytic nodule along the cyst wall, mimicking pneumonia. Additional chemotherapy, but not antibiotic therapy, l
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Sanampudi, Sreeja, Margaret Kypreos, Sameer Chabbra, and Kiran Batra. "Paraseptal Lucencies Mimicking Emphysema in a Non-smoker With Acute Lung Injury in COVID-19." Cureus, October 7, 2024. http://dx.doi.org/10.7759/cureus.71010.

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