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Dissertations / Theses on the topic 'Parasites – Immunologie'

Author: Grafiati

Published: 4 June 2021

Last updated: 15 February 2022

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1

Renaux, Sophie. "Eimeria du lapin : étude de la migration extra-intestinale du sporozoïte et du développement de l'immunité protectrice." Tours, 2001. http://www.theses.fr/2001TOUR3802.

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2

Moulia, Catherine. "Modalités des interactions génétiques dans les systèmes hôte-parasite : l'association nématodes (oxyures) : muridés (Mus) en zone d'hybridation hôte." Montpellier 2, 1992. http://www.theses.fr/1992MON20199.

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La dysgenese d'individus au genome recombinant du centre de la zone hybride entre les deux sous-especes de souris domestiques europeennes mus musculus domesticus et m. M. Musculus est etudiee a travers les modalites de resistance/susceptibilite des souris aux nematodes intestinaux (oxyures). Nous verifions et confirmons tout d'abord in situ dans la partie danoise de la zone d'hybridation hote la surinfestation hybride constatee en allemagne par d'autres auteurs; puis, nous montrons par des infestations experimentales controlees de souris de type parental et de souris de la zone hybride danoise

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3

Cellier, Mathieu. "Elaboration de modèles expérimentaux pour l'étude des stress cellulaires dans les interactions hôte - agent pathogène." Montpellier 2, 1992. http://www.theses.fr/1992MON20205.

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Au cours de processus infectieux, les interactions entre pathogenes intracellulaires et macrophages peuvent declencher des reactions cellulaires apparentees a la reponse au choc thermique. Ces reactions impliquant des proteines specifiques appelees proteines de stress (hsp) ont ete etudiees en utilisant comme modele la lignee leucemique humaine u937 et la bacterie brucella. Nous avons montre qu'un choc thermique sub-lethal permet d'induire la differenciation des cellules myelomonocytaires. Les resultats obtenus suggerent une adaptation fonctionnelle au stress des cellules monocytaires permetta

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4

Nicolas-Gaulard, Isabelle. "Activité immunomodulatrice d'une protéine, l'hypodermine A, sur les cellules sanguines mononucléées des bovins." Paris 12, 1995. http://www.theses.fr/1995PA120031.

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Parmi les grandes maladies parasitaires qui affectent le cheptel bovin francais, l'hypodermose est responsable de pertes economiques importantes. Le premier stade larvaire de l'insecte responsable de cette parasitose provoque une desorganisation des systemes de defense de l'hote. Ces defaillances sont causees par les secretions larvaires et principalement par l'hypodermine a (ha). L'objet de ces travaux est l'etude de l'activite immunomodulatrice de l'ha sur les cellules sanguines mononucleees des bovins. L'ha inhibe la proliferation des lymphocytes apres stimulation par une lectine mitogene o

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5

Gay, Frédérick. ""Chimiorésistance de "Plasmodium falciparum" : études sur les populations impaludées et sur les populations plasmodiales"." Montpellier 2, 1992. http://www.theses.fr/1992MON20277.

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La chimioresistance de plasmodium falciparum est etudiee a travers les populations impaludees et au sein des populations plasmodiales. Les trois outils mis en uvre sont l'epidemiologie, la recherche clinique et la recherche fondamentale. Les resultats concernant les populations impaludees portent sur l'evolution des taux d'incidence d'acces palustre chez les voyageurs, l'evolution des taux de prevalence et des niveaux de chimioresistance en afrique de l'ouest et le role de la biodisponibilite dans l'interpretation des echecs therapeutiques. Les travaux portant sur les populations plasmodiales

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6

Dupas, Stéphane. "La suppression immunitaire dans le système drosophile-parasitoi͏̈de : aspects physiologiques, génétiques et évolutifs." Montpellier 2, 1998. http://www.theses.fr/1998MON20015.

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L'objectif de cette these est d'etudier les variations de l'aptitude immunosuppressive du parasitoide leptopilina boulardi vis-a-vis de son l'hote drosophila melanogaster d'un point de vue physiologique, genetique et evolutif. D'un point de vue physiologique nous avons montre que la reaction de l'hote se mettait en place suite au depot precoce d'une fine couche dense aux electrons a la surface du chorion de l'uf (vraisemblablement de la melanine). De son cote, le parasitoide produit des particules d'allure virale (vlps) responsables de l'immunosuppression et reagissant positivement aux colorat

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7

Laugier, Claire. "Contribution à l'étude des infestations par des petits strongles chez le cheval en Normandie : données épidemiologiques et aspects lésionnels." Montpellier 2, 2002. http://www.theses.fr/2002MON20125.

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8

Girod, Anne. "Production de vecteurs rétroviraux par des lignées transcomplémentantes aviaires : augmentation du titre en vecteurs et analyse des formes virales parasites produites." Lyon 1, 1995. http://www.theses.fr/1995LYO10312.

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Le laboratoire a developpe, a partir de retrovirus aviaires de type alsv, des lignees transcomplementantes productrices de particules vecteurs en condition helper-free. Nous avons ici recherche a augmenter le titre en particules produites par ces lignees transcomplementantes et analyse les formes virales recombinantes generees par ces systemes. L'introduction du genome vecteur dans la lignee d'empaquetage par infection plutot que par transfection a permis d'accroitre les titres des stocks de vecteurs retroviraux a des valeurs de 10#6 efu-(expressing forming unit)/ml. En revanche, le systeme pi

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9

BAHRI, SIHEM, and ADAM MARQUES. "Etude comparee de quelques myxosporidies parasites de poissons mugilidae de mediterranee occidentale : aspects structuraux, biologiques et immunologiques." Montpellier 2, 1997. http://www.theses.fr/1997MON20005.

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Cette etude porte sur les myxosporidies parasites des muges de mediterranee occidentale principalement mugil cephalus et liza ramada provenant du lac ichkeul de tunisie. Les donnees ultrastructurales ont permis de differencier 7 especes du genre myxobolus dont trois nouvelles m. Bizerti n. Sp. ; m. Ichkeulensis n. Sp. ; m. Ramadae n. Sp. , formant des kystes branchiaux. Trois formes viscerales ont ete identifiees: m. Spinacurvatura ; m. Mulleri, localisees dans les vaisseaux mesenteriques et m. Exiguus infestant la paroi intestinale. La 7eme espece recoltee au niveau du tegument a ete rattache

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10

Ben, Abderrazak Souha. "Variabilité génétique des populations de "Plasmodium falciparum"." Montpellier 2, 1993. http://www.theses.fr/1993MON20013.

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Nous avons analyse par electrophorese d'isoenzymes (7 a 12 loci) le polymorphisme genetique de 5 populations (113 stocks) du plasmodium falciparum, l'agent de la forme la plus severe de paludisme. Les resultats ont ete interpretes en termes de genetique des populations, dans le but d'analyser la structure des populations naturelles de ce parasite. Un fort desequilibre de liaison apparait dans trois des populations etudiees, ainsi que dans l'echantillon global. Une quatrieme population montre egalement des indices de desequilibre, quoique dans une moindre mesure. Une seule serie n'a montre aucu

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11

Bekkaoui, Abdelhamid. "Rôle de stimulus chimiques de contact dans la reconnaissance des chrysalides-hôtes par diadromus pulchellus Wsm. (hymenoptera), parasitoïde du phytophage acrolepiopsis assectella Zell. (lepidoptera)." Tours, 1992. http://www.theses.fr/1992TOUR4005.

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Le comportement de reconnaissance de l'hôte par l'hyménoptère diadromus pulchellus wsm, parasitoïde des chrysalides d'acrolepiopsis assectella zell, la teigne du poireau, semble détermine en très grande partie, sinon exclusivement, par des stimulus chimiques de contact liés à la cuticule et au cocon de l'hôte. Ces kairomones semblent être des molécules hydrophiles de faible taille et très spécifiques. Elles ne sont en effet pas retrouvées dans la soie de lépidoptères non hôtes. L'élevage de la teigne sur un milieu artificiel pauvre en substances du poireau ou même n'en contenant pas du tout, à

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12

Ali, Magdi Mahmoud M. "The immunologic aspects of the pathogenesis of human onchocerciasis /." Stockholm : Dept. of immunology, Wenner-Gren institute, Stockholm university, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-793.

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13

Jemli, Mohamed Habib. "Fasciolose ovine à Fasciola hepatica : contribution à son étude immunologique et biochimique." Toulouse, INPT, 1991. http://www.theses.fr/1991INPT015A.

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L'auteur etudie la fasciolose a fasciola hepatica chez le mouton, dans le double but de mieux connaitre la physiopathologie de la maladie et d'obtenir des moyens de diagnostic precoces et fiables. Apres un rappel concernant la maladie et ses consequences pathologiques et immunitaires, l'auteur presente les methodes d'etude puis les resultats obtenus chez des moutons infestes experimentalement par 200 metacercaires de grande douve en infestation unique. Il rapporte les perturbations immunologiques et biochimiques observees au cours de cette infestation, en remarquant surtout une augmentation im

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14

Marche, Hélène. "Etude de l'interférence d'une épi-drogue sur l'expression génique et la croissance intracellulaire de Toxoplasma gondii." Thesis, Université Grenoble Alpes (ComUE), 2019. http://www.theses.fr/2019GREAV019/document.

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Toxoplasma gondii est un parasite protozoaire intracellulaire obligatoire, et est l’agent responsable de la toxoplasmose, une parasitose habituellement bénigne chez le sujet immunocompétent ou en dehors d'une grossesse. Lorsqu’elle est congénitale, la toxoplasmose peut se manifester par de malformations neurologiques sévères. Cette maladie se développe sous deux formes. La première comprend à la phase aigüe provoquée par l’expansion de la population de tachyzoites qui peuvent provoquer des malformations chez le fœtus. La seconde est dite chronique et asymptomatique, le bradyzoite est y présent

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15

Israelsson, Elisabeth. "The role of antibody mediated parasite neutralization in protective immunity against malaria." Licentiate thesis, Stockholm University, Wenner-Gren Institute for Experimental Biology, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-7137.

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16

Huppé, Vicky. "Analyse de l'eau de sources naturelles en régions éloignées et étude de gènes conservés dans l'évolution des parasites protozoaires retrouvés dans l'eau." Thesis, Université Laval, 2009. http://www.theses.ulaval.ca/2009/26419/26419.pdf.

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17

Mounkassa, Jean-Bruno. "Compétition interspécifique Schistosome-Echinostome chez le Mollusque vecteur : approche immunologique des mécanismes de compétition." Montpellier 2, 1987. http://www.theses.fr/1987MON20185.

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Etude de la competition larvaire entre schistosome et echinostome chez les mollusques hotes-intermediaires. Les resultats mettent en evidence une dominance totale de l'echinostome sur le shistosome dans toutes les situations experimentales testees (infestations mixtes simultanees, infestations mixtes decalees). Cette dominance est caracterisee par une inhibition du developpement larvaire du schistosome suivie d'une degenerescence totale des stades larvaires. L'analyse des mecanismes de competition a revele que la dominance de l'echinostome est mediee par le systeme immunitaire de l'hote

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18

Yilma, Jobre Makonnen. "Contribution à l'étude de l'épidémiologie, du diagnostic immunologique et de la physiopathologie de l'oestrose ovine (oestrus ovis linne 1761)." Toulouse, INPT, 1992. http://www.theses.fr/1992INPT036A.

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Une etude epidemiologique effectuee dans le sud-ouest a revele une prevalence elevee de l'infestation par oestrus ovis. L'evolution larvaire qui est fonction de la temperature exterieure et du niveau de precipitations, comprend une courte phase estivale de developpement actif et une phase prolongee d'inhibition hivernale. Des essais d'infestations experimentales ont confirme l'influence des facteurs climatiques sur la dipause. Dans une etude de simulation de l'strose par des transplantations larvaires repetees, des resultats ante mortem et post mortem significativement differents ont ete obser

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19

Åhlin, Erik. "Functional Role of Immune Complexes in Rheumatic and Parasitic Diseases." Doctoral thesis, Uppsala universitet, Klinisk immunologi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-139529.

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Immune complexes (IC) have key pathological roles in both autoimmune and infectious diseases. In this thesis functional mechanisms behind IC-driven inflammation in rheumatic diseases and tropical infections have been studied, with special focus on the contribution of autoantibodies and cytokine-inducing properties of IC. In the autoimmune disease SLE, increased levels of IC-induced cytokines were associated with both increased classical complement activation and the occurrence of the autoantibodies anti-SSA and anti-SSB, both directed against RNA-associated antigens. In addition, complement ac

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20

Rezvan, Hossein. "Studies on immunology of Leishmania mexicana." Thesis, Nottingham Trent University, 2007. http://irep.ntu.ac.uk/id/eprint/181/.

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Leishmaniasis is a worldwide disease prevalent in many tropical and sub tropical countries. Treatment of Leishmaniasis by chemotherapy is not wholly effective and is usually accompanied by unpleasant side effects. The development of an effective and inexpensive vaccine represents a practical way to control the disease, however at present no safe and effective vaccine is available. In the first part of the present study, the immunity induced by four different L. mexicana potential vaccines, including killed leishmania vaccine, Soluble L. mexicana Antigen (SLA), L. mexicana gp63 cDNA and CT26 tu

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21

Davis, Richard Elliot. "Neutrophil responses to infection with leishmania parasites: MHC class II-expression and parasite life-stage interactions." Diss., University of Iowa, 2016. https://ir.uiowa.edu/etd/2200.

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The vector-borne protozoan Leishmania spp. cause the spectrum of disease known as leishmaniasis in human and animal hosts. The most common manifestations of leishmaniasis are the chronic, ulcerative skin disease cutaneous leishmaniasis (CL), and the more serious visceral leishmaniasis (VL) in which parasites take up residence in internal organs, causing death if not treated. The role of neutrophils (PMNs) in the immune response to CL and VL is unclear. It is s generally thought that PMNs are only a short-lived effector cell, and have been disregarded as playing a role in chronic Leishmania spp

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22

Lellouche, Eric. "L'immunité locale dans deux parasitoses oculaires, toxoplasmose et onchocércose." Paris 5, 1993. http://www.theses.fr/1993PA05P084.

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23

Jeneby, Maamun. "Haemoprotozoan Parasites of Non-Human Primates in Kenya : Studies on Prevalence and Characterization of Haemoprotozoan Parasites of Wild-Caught Baboons, African Green Monkeys and Syke's Monkeys." Doctoral thesis, Uppsala universitet, Försöksdjursvetenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-150467.

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This thesis reports on cross-sectional surveys aimed at detecting and characterizing haemoprotozoan parasites infecting wild free-ranging non human primates (NHPs) in Kenya, East Africa. Blood samples from olive baboons (Papio cynocephalus anubis), vervet monkeys or African green monkeys (AGMs, Chlorocebus aethiops) and Syke's monkeys (Cercopithecus mitis) from five provinces of Kenya were analyzed. The haemoprotozoan parasites survey was performed with microscopic evaluation of blood smears, serological techniques and molecular tools. Blood specimens and serum samples from 121 NHPs were teste

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24

Geoffroy, Patrick. "Place du granulome bilharzien dans l'interaction immunologique parasite hôte chez "Schistosoma mansoni"." Paris 5, 1990. http://www.theses.fr/1990PA05P240.

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25

Mohammed, Shawn Rasheed. "Disaccharidase deficiencies in gerbils (Meriones unguiculatus) immune to Giardia lamblia." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=55514.

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Studies using Mongolian gerbils found that during a primary infection with Giardia lamblia trophozoites, disaccharidase activities were decreased from day 10 post-infection (p.i.) until well past elimination of the parasite. However, during a challenge infection, enzyme deficiencies were short-lived. A challenge with a soluble extract of G. lamblia trophozoites also resulted in reductions in disaccharidase activity. The degree of these reductions in enzyme activity was dependent on the extract dose. Gel filtration of the trophozoite crude extract resulted in fractions F1, F2, and F3. However,

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26

Anderson, Barry Clayton. "The Response of Mice to Infection by the Parasitic Nematode Trichinella: A Comparison of Trichinella Spiralis and Trichinella Pseudospiralis." PDXScholar, 2002. https://pdxscholar.library.pdx.edu/open_access_etds/1658.

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The intracellular parasite Trichinella is a genus in phylum Nematoda that contains six named species including Trichinella spiralis and Trichinella pseudospiralis. These parasites infect a large variety of wild and domestic animals, human beings and a few species of birds. The parasitic strategies and the pathological effects on the host between trichinella spiralis and Trichinella pseudospiralis are quite different. The purpose of this study is to gain an understanding of the physiological, immunological and pathological differences between these two species of Trichinella using infections in

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27

McSorley, Henry. "TGF-β homologues from parasites : inducers of immune regulation?" Thesis, University of Edinburgh, 2008. http://hdl.handle.net/1842/3157.

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Many helminth parasites are able to survive for long periods in immunocompetent hosts. It has been suggested that the successful establishment of helminths is in part due to the induction of regulatory T cells (Tregs) which suppress anti-parasite immune responses. A possible mechanism by which parasites induce Tregs would be production of TGF-β, which can induce immunosuppressive Treg cells and also directly suppress immune responses. TGF-β homologues have been identified in parasitic nematodes including Brugia malayi, Schistosoma mansoni and Ancylostoma caninum. The B. malayi TGF-β homologue,

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28

Contreras, Garcia Irazú. "Modulation of the host innate immune response by «Leishmania» parasites." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=95096.

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Leishmania parasites have evolved sophisticated mechanisms to subvert macrophage immune responses in order to survive inside the mammalian host. Among these mechanisms are the rapid activation of phosphatases that in turn will inactivate protein kinases and transcription factors, causing abrogation of nitric oxide (NO) production and induction of immunosuppressive molecules. This doctoral thesis discusses novel mechanisms of how the parasite modulates the immune response of macrophages and dendritic cells. Herein, we describe the role of Myeloid Related Proteins (MRPs) 8 and 14 during Leishma

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29

Missoh, Claudia. "Division of labor in anti-parasite defense strategies in ant colonies." Thesis, Paris 6, 2014. http://www.theses.fr/2014PA066450/document.

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La division du travail est une caractéristique clé chez les insectes sociaux et contribue à leur succès écologique. En ce qui concerne les tâches sanitaires, la division du travail au sein d’une colonie peut permettre de réduire la transmission des maladies, de libérer certaines ouvrières pour d’autres tâches, permettant de diminuer les couts associés à l’exécution des tâches sanitaires (sur le plan comportementale et physiologique). Les facteurs externes et internes aux individus déterminant leur participation aux tâches sanitaires ne sont pas bien connus. La plupart des études portent sur l’

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30

Baeza, Elisabeth. "Suivi de la réponse immunitaire précoce aspécifique chez le rat infesté expérimentalement par "Fasciola hepatica"." Montpellier 2, 1992. http://www.theses.fr/1992MON20261.

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Ce travail est une contribution a l'analyse des mecanismes immunitaires precoces qui se mettent en place au cours d'une infestation par f. Hepatica chez le rat. Apres la mise au point d'une technique d'infestation experimentale du rat, la repetabilite de ce type d'infestation a ete verifiee. Une etude de l'evolution de proteines de la reaction inflammatoire et des leucocytes au cours de la phase precoce de la fasciolose a montre une absence de modification de ces marqueurs de l'inflammation pendant les deux premieres semaines qui suivent l'infestation. L'immunomodulation de la reponse inflamma

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31

Jacobs, Brittany-Amber. "Cancer cell behaviour following parasite exposure." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29273.

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Infectious diseases, including helminthiases, are estimated to cause 16.1% of global cancer cases. While certain helminths are conclusive causes of cancer, others have been shown to reduce the disease. It is currently unknown why differing helminth infections promote or prevent cancer development and progression, or which cellular mechanisms are altered following exposure. Using several in vitro and in vivo techniques, this study aimed to determine the effect that certain helminths have on the progression of cervical and colorectal cancer. The results revealed that antigen from the hookworm Ni

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32

Anderson, Laura Fay. "Malaria proteins implicated in host-parasite interactions." Thesis, University of Edinburgh, 2007. http://hdl.handle.net/1842/1965.

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The invasive and transmission stages of the malaria parasite Plasmodium falciparum express several proteins with domains implicated in host-parasite interactions, that are potential vaccine candidates or drug targets. The expression patterns of two proteins PfTRAMP (Plasmodium Related Apical Merozoite Protein) and PCRAGS (Plasmodium cysteine related antigen of gametocytes and schizonts), containing such putative domains, are examined and their potential roles in merozoite invasion and egress are discussed. PfTRAMP has a possible role in merozoite invasion. Transcription occurs in mature schizo

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33

Ben-Smith, Anne. "Mechanisms of expulsion of primary infections of Heligmosomoides polygyrus in mice." Thesis, University of Nottingham, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284027.

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34

Oldridge, Joanne. "Molecular and immunological characterisation of two vaccine dominant antigens of Schistosoma mansoni." Thesis, London School of Hygiene and Tropical Medicine (University of London), 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.307435.

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35

Bartley, Paul Murdoch. "Host-parasite interactions of Neospora caninum." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/23592.

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The papers included in this thesis examine the host–parasite relationship in small and large animals following experimental challenges with Neospora caninum. This apicomplexan parasite is a major cause of abortion and reproductive losses in cattle worldwide. Economic and welfare issues make the development of a vaccine against the transplacental transmission of Neospora highly desirable. This thesis evaluates the host-parasite interactions in a non-pregnant mouse model examining whether the actively multiplying stage of the parasite (tachyzoite) could be attenuated through prolonged in vitro c

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36

THIAM, KADER. "Strategie de modulation de la reponse immune : du vecteur vivant au lipopeptide synthetique (doctorat : immunologie parasitologie)." Lille 2, 1999. http://www.theses.fr/1999LIL2T004.

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37

Jecock, Rowena M. "Studies on GP30 and other developmentally-regulated proteins of Brugia pahangi." Thesis, University of Liverpool, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333555.

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38

Kadian, Surinder Kumar. "Immunoregulation in metacestode infections : modification of macrophage accessory activity by tetrathyridia of Mesocestoides corti." Thesis, University of Liverpool, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240521.

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39

Pattaradilokrat, Sittiporn. "Linkage group selection to investigate genetic determinants of complex traits of malaria parasites." Thesis, University of Edinburgh, 2008. http://hdl.handle.net/1842/3139.

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Malaria parasites of the species infecting humans and animal hosts exhibit genetic and phenotypic diversity. Some of this diversity, including the responses to anti-malarial drugs, growth rate and virulence and antigenic variability, is medically significant. This is because these phenotypes may determine the existence and survival of the parasites in the host and, in turn, contribute to the clinical outcome of infection. Understanding of the biological characteristics and the genetic basis underlying these complex phenotypes can thus lead to the development of effective control strategies aga

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40

Bolad, Ahmed Kamal. "Antibody responses in Plasmodium falciparum malaria and their relation to protection against the disease." Doctoral thesis, Stockholm : Wenner-Grens institut, Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-37.

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41

Paterson, Jacqueline C. M. "Modulation of T cell responses by the products of Ascaris suum." Thesis, University of Glasgow, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312783.

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42

Hayward, Adam David. "Parasites and life history variation in a wild mammal." Thesis, University of Edinburgh, 2011. http://hdl.handle.net/1842/5675.

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The purpose of this thesis is to investigate associations between parasite infection and host life-history variation in the wild Soay sheep population of the islands of St Kilda, NW Scotland. Studying host-parasite interactions in wild animal populations is of interest because of the importance of heterogeneity in resource availability, genetics, and environmental conditions in determining resistance to parasites, with implications for human populations and wildlife conservation and management. However, very few studies are able to investigate these associations in a longitudinal manner, which

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Steed, Lisa Lovett. "Host-parasite interactions between Bordetella pertussis and human polymorphonuclear leukocytes." Diss., The University of Arizona, 1991. http://hdl.handle.net/10150/185641.

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Little is known regarding the interaction of Bordetella pertussis with polymorphonuclear leukocytes (PMNL) or the role PMNL play as an initial line of defense against B. pertussis infection. An in vitro system was developed to establish optimum conditions for the study of phagocytosis and killing of three virulent strains of B. pertussis and a series of derivative mutants using strictly human PMNL and sera. Optimum phagocytosis of B. pertussis occurred by opsonization with human anti-B. pertussis antibody (HAPA), while autologous normal sera (NS) did not induce significant phagocytosis. An ant

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Yourth, Christopher Paul. "Ecological immunology of lestid damselflies, explaining variation in immune defense against parasitic water mites." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp05/MQ63244.pdf.

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Bucsu, Eva. "Plasmodium chabaudi adami : vaccine antigens and antigenic variation /." Connect to thesis, 2003. http://repository.unimelb.edu.au/10187/2881.

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There is an abundance of information available on the molecular mechanisms of antigenic variation in Plasmodium falciparum. The variant antigen PfEMP1, which mediates antigenic variation as well as cytoadherence and rosetting, has been extensively characterised. Genes coding for the antigen belong to the gene family var, and several var genes have been cloned and characterised. The rodent malaria parasite P. chabaudi is a widely studied in vivo model for P. falciparum. The P. c. chabaudi AS parasite strain has been shown to exhibit antigenic variation and the variant antigen has been detected

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Taylor, Jesse Earl. "Host structuring of parasite populations: Some theoretical and computational studies." Diss., The University of Arizona, 2003. http://hdl.handle.net/10150/289991.

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Because the ecological and the genetic interactions occurring between parasites belonging to different infections are constrained by the physical discreteness of the hosts, the host-parasite association imparts a spatial structure to the populations of parasitic microorganisms. Equating infections with demes or islands, the parasite population can be described by a variant of Wright's island model, in which recovery and infection correspond to extinction and colonization and superinfection corresponds to migration. Here we investigate some of the population genetic consequences of host structu

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Diaz, Yacobazzo Alvaro Juan. "A search for mechanism restricting activation of the host complement system in Echinococcus granulosus." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.361948.

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Dehlawi, M. S. "Mast cell responses to intestinal nematodes in mice." Thesis, University of Nottingham, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376170.

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De, Aguiar J. C. S. "Studies on the polymorphic schizont antigen of Plasmodium chabaudi." Thesis, Open University, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.383640.

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Ahmed, Rubina. "Elucidation of the role of mannose binding lectin and ST2 in the immune response to the parasitic helminth Brugia malayi." Thesis, Royal Veterinary College (University of London), 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.559018.

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