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Relevant bibliographies by topics / Parasitology (biology)

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Academic literature on the topic 'Parasitology (biology)'

Author: Grafiati

Published: 4 June 2021

Last updated: 4 March 2023

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Journal articles on the topic "Parasitology (biology)"

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Esch, Gerald W., William C. Marquardt, Richard S. Demaree, and Robert B. Grieve. "Parasitology & Vector Biology." Journal of Parasitology 87, no. 3 (June 2001): 647. http://dx.doi.org/10.2307/3285106.

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McVeigh, Paul. "Post-genomic progress in helminth parasitology." Parasitology 147, no. 8 (April 7, 2020): 835–40. http://dx.doi.org/10.1017/s0031182020000591.

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AbstractHelminth parasitology is an important discipline, which poses often unique technical challenges. One challenge is that helminth parasites, particularly those in humans, are often difficult to obtain alive and in sufficient quantities for study; another is the challenge of studying these organisms in vitro – no helminth parasite life cycle has been fully recapitulated outside of a host. Arguably, the key issue retarding progress in helminth parasitology has been a lack of experimental tools and resources, certainly relative to the riches that have driven many parasitologists to adopt free-living model organisms as surrogate systems. In response to these needs, the past 10–12 years have seen the beginnings of helminth parasitology's journey into the ‘omics’ era, with the release of abundant sequencing resources, and the functional genomics tools with which to test biological hypotheses. To reflect this progress, the 2019 Autumn Symposium of the British Society for Parasitology was held in Queen's University Belfast on the topic of ‘post-genomic progress in helminth parasitology’. This issue presents examples of the current state of play in the field, while this editorial summarizes how genomic datasets and functional genomic tools have stimulated impressive recent progress in our understanding of parasite biology.

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SIKOROWSKI, Karol, Tomasz NIEMIEC, Ewa Czerniawska-Piątkowska, Mateusz MAKARSKI, Bartłomiej J. BARTYZEL, Sławomir PAŚKO, and Piotr KOCZOŃ. "BIOLOGY AND PARASITOLOGY OF EUROPEAN BEAVER (CASTOR FIBER L. 1758) – SELECTED ISSUES." Folia Pomeranae Universitatis Technologiae Stetinensis Agricultura, Alimentaria, Piscaria et Zootechnica 328, no. 39 (December 5, 2016): 203–10. http://dx.doi.org/10.21005/aapz2016.39.3.17.

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Oetinger, David F., E. R. Noble, G. A. Noble, G. A. Schad, and A. J. MacInnis. "Parasitology: The Biology of Animal Parasites." Journal of Parasitology 75, no. 6 (December 1989): 1008. http://dx.doi.org/10.2307/3282891.

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ESCH, GERALD W. "BOOK REVIEW: Parasitology & Vector Biology." Journal of Parasitology 87, no. 3 (June 2001): 647. http://dx.doi.org/10.1645/0022-3395(2001)087[0647:br]2.0.co;2.

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Nussenzweig, V. "Parasitology, genetics and cell biology intertwined." Current Opinion in Microbiology 4, no. 4 (August 1, 2001): 399–401. http://dx.doi.org/10.1016/s1369-5274(00)00225-3.

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Greve, John H. "Parasitology—The biology of animal parasites." Veterinary Parasitology 35, no. 1-2 (February 1990): 179–81. http://dx.doi.org/10.1016/0304-4017(90)90130-4.

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HOLLINGDALE, M. R. "Parasitology at MBL: The Biology of Parasitism." Science 246, no. 4935 (December 8, 1989): 1330–31. http://dx.doi.org/10.1126/science.246.4935.1330-a.

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Prichard, Roger. "Application of molecular biology in veterinary parasitology." Veterinary Parasitology 71, no. 2-3 (July 1997): 155–75. http://dx.doi.org/10.1016/s0304-4017(97)00029-0.

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Prichard, Roger, and Andy Tait. "The role of molecular biology in veterinary parasitology." Veterinary Parasitology 98, no. 1-3 (July 2001): 169–94. http://dx.doi.org/10.1016/s0304-4017(01)00429-0.

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Dissertations / Theses on the topic "Parasitology (biology)"

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Hayward, Rhian Elizabeth. "The biology of Plasmodium falciparum gametocytes." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360296.

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Ahari, Esmaeil Ebrahimzadeh. "Studies on the biology of Schistosoma margrebowiei." Thesis, Bangor University, 1992. https://research.bangor.ac.uk/portal/en/theses/studies-on-the-biology-of-schistosoma-margrebowiei(6450c229-e685-4746-bb42-2735e73ca54e).html.

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Studies on the biology of Schistosoma margrebowiei include, a simple means of culturing and infecting Bulinus natalensis snails; the morphology and ultrastructure of various stages in the life-cycle; pathology; cercarial longevity and infectivity; cross-reactivity with S. mansoni rabbit anti-sera and the possible use of S. margrebowiei egg homogenate in the serodiagnosis of S. haematobium patients. A simple method of maintenance and infection of B. natalensis snails en masse, was found to yield a rapid and continuous supply of material. The results indicate that the size of snails at the time of exposure is an important factor in successful infection. A wide range of morphological and ultrastructural similarities were found between S. margrebowiei larval stages and those of other species of the genus. Whereas the adult worms are among the largest, the eggs, miracidia and cercariae of S. margrebowiei, are among the smallest in the genus. The pathology associated with S. margrebowiei, is due to deposition of large numbers of eggs in various organs of the infected animal. Eggs were not only recovered from the liver and intestine but following 50 days post-infection, from the spleen. A large number (10-15%) of the total eggs recovered from mice 45 to 65 days post-infection were deposited in the spleen. The cercariae of S. margrebowiei by utilizing their glycogen reserves, can live for up to 70 hours in fresh water at temperatures of 26-28°C. This observed life-span can be prolonged when water temperatures were decreased to 8-12 °C. Cercariae kept in cold water although physically active and still infective, were found to be attenuated as measured by a reduced percentage of recovered worms compared with controls. The potential for immunizing mice with the hepatopancreas from infected and uninfected snails against schistosomiasis has been evaluated using S. mansoni. Although a reduction in the number of worms and eggs was observed in mice immunized with infected hepatopancreas when compared to the controls, this decrease was not significant. Sera from 53 patients infected with schistosomiasis were studied by ELISA using S. margrebowiei crude soluble egg antigen (SEA), S. mansoni SEA and cationic S. mansoni egg antigen (CEF6). It was found that S. margrebowiei SEA was more specific for the identification of S. haematobium infections.

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Tallin, Michelle. "The biology of Mesocestoides corti infection in laboratory rodents." Thesis, University of Portsmouth, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.241075.

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Stewart, Alexander Thomas. "Eco-immunology : thermal variation and parasitology of the three-spined stickleback." Thesis, Cardiff University, 2016. http://orca.cf.ac.uk/95911/.

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Global warming and temperature variation are likely to have profound impacts on fish as ectotherms that are heavily reliant on environmental temperature for growth, development, metabolism and immunity. This study addresses the impact of climate change on the development of infection and immunity in three-spined sticklebacks (Gasterosteus aculeatus) and their common parasites. In addition to thermal consequences on host parasite interactions, the study also addressed the effects of co-infection on parasite intensities and pathology on host swimming ability. Experiments were designed to mimic global warming, temperature variability and stochasticity (Chapters 3-5). Temperature during exposure to Saprolegnia parasitica was the major determinant of high infection prevalence and intensity with historical temperature exposure having little impact (Chapters 3-5). A further contributor to infection risk was higher host body condition (Chapter 3 and 5), attributed to a trade-off between host immunity and condition, higher condition individuals investing less in immunity supported by a decline in β-def expression in high condition fish (Chapter 5). Peak infection intensities in Gyrodactylus gasterostei were dependent on temperature variability and the host’s immune response. In variable conditions, an established G. gasterostei was better able to adapt to a changing environment than the host’s response causing higher peak infection intensities (Chapter 3 and 4). Temperature, and not photoperiod, was the major cause of circannual rhythm in host immunity (Chapter 6). Co-infection between G. gasterostei and A. foliaceus, revealed higher gyrodactylid infection peaks compared to hosts infected with G. gasterostei alone suggesting that immunomodulation by A. foliaceus. Lastly, pathology, rather than drag, reduced burst and long-term swimming performance of sticklebacks infected with A. foliaceus. Many of the factors highlighted have implications for aquaculture. High aquaculture feeding regimens, resulting in higher body condition, co-infection and temperature, all could severely increase morbidity and mortality of fish in a parasite species dependant manner.

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Pilar, Ana Victoria. "Biochemical and molecular characterization of the glycosomal PTS2 import receptor peroxin 7 in «Leishmania donovani»." Thesis, McGill University, 2009. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=32255.

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The Leishmania peroxin 7 (LmPEX7 or LdPEX7) is the receptor that translocates PTS2 signal-containing proteins into the glycosome. This microbody is unique to and crucial for the survival of trypanosomatids which include Leishmania and Trypanosoma, the causative agents of leishmaniasis and African sleeping sickness, respectively. Proteins are imported into the glycosome via two pathways, PTS1 and PTS2, which involves the formation of a PTS-receptor complex in the cytosol, docking of the complex on a translocation apparatus on the glycosomal membrane, and subsequent release of the cargo protein into the lumen. However, the precise steps in glycosome protein trafficking are not well-defined and to understand the function of these organelles and prove their potential as chemotherapeutic targets, the mechanism of glycosome biogenesis needs to be fully elucidated. Not much is known about the mechanism of PTS2 import pathway in glycosomes as studies on PEX7 have been hampered by the difficulty in expressing a soluble recombinant form of this receptor. To dissect the PTS2 import pathway and to determine the role of PEX7 in Leishmania, this protein was cloned and characterized. LmPEX7 is a ~41 kDa protein containing six conserved WD40 motifs that displays limited sequence similarity to PEX7 homologues involved in the biogenesis of evolutionarily-related peroxisomes found in other eukaryotes. LmPEX7 interacts with PTS2 proteins, the PTS1 receptor LdPEX5, and the membrane-associated docking protein LdPEX14. These interactions, characterized through various biochemical techniques, were mediated by specific binding domains, formation of stable protein-protein complexes, and conform
La péroxine Leishmania 7 (LmPEX7 ou LdPEX7) est un récepteur qui transloque les protéines qui contiennent le signal PTS2 dans le glycosome. Ce glycosome est unique et critique aux trypanosomes, tels que Leishmania et Trypanosoma, les agents causant la leishmaniose et la maladie Africaine du sommeil. Les protéines sont importées vers le glycosome par deux voies, PTS1 et PTS2, qui nécessitent la formation d'un complexe PTS dans le cytosol, l'amarrage du complexe sur un appareil de translocation sur la membrane du glycosome, et permet la liberation de la charge protéique dans le lumen. Par contre, les étapes précises dans l'acheminement de protéines glycosomales ne sont pas bien définies et pour comprendre les fonctions de ces organelles et prouver qu'elles être des cibles chimiothérapiques, les mécanismes impliqués dans la biogenèse doivent être très bien élucidés. Pour disséquer le mécanisme d'importation et pour déterminer le rôle de PEX7 chez Leishmania, cette protéine a été clonée à partir de l'ADN génomique de L. major et a été caractérisée. LmPEX7 est une protéine d'environ 41 kDa qui démontre une homologie limitée aux PEX7 impliqués dans la biogenèse des peroxysomes chez autres eucaryotes. LmPEX7 interagit avec les protéines PTS2, le récepteur PTS1 LdPEX5, ainsi que la protéine LdPEX14 qui est associée à la membrane du glycosome. Ces intéractions, décrites en utilisant des techniques biochimiques variées, sont arbitrés par des domaines d'interactions situés sur LdPEX5 et LdPEX14, la formation de complexes protéiques stables, et associée à divers changements conformationnels. Des études de localisation subcellula

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Geukers, Karen. "Characterization of CFF in the sera of plasmodium-infected mice." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=104816.

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The objective of this study was to further characterize the inhibitory serum protein crisis form factor, or CFF, and identify candidate proteins responsible for CFF activity. Four models for serum CFF induction were tested: C57BL/6 mice infected with P. chabaudi adami AS, C57BL/6 mice inoculated with BCG + LPS, and BALB/c mice infected with P. chabaudi adami DS or DK. C57BL/6 mice infected with P. chabaudi adami AS produced sera with the most pronounced level of inhibitory activity and were used for CFF analysis. Heat inactivation did not affect CFF activity, indicating the observed effect was not due to complement proteins, function was lost after heating serum to 100°C. Gel filtration determined that CFF may be in the range of 20 kDa – 80 kDa. Serum depletion by IgY retained CFF activity in the low abundance protein fraction (LAP), which was analyzed by MALDI and LC-QToF mass spectrometry and compared to the LAP from naïve mice. A total of 68 proteins were identified as either up-regulated or unique to the CFF serum, and qualitative analysis revealed one potential CFF candidate: neutrophil gelatinase-associated lipocalin. In conclusion, we have established a model for inducing serum CFF, characterized some of its physical properties, and through proteomic analysis identified a potential CFF candidate.
L'objectif de cette étude visait d'une part à approfondir la caractérisation du facteur de la forme de crise (CFF; « crisis form factor »), un facteur protéique inhibiteur présent dans le sérum, et d'autre part à identifier des protéines candidates responsable de l'activité de CFF. Quatre modèles murins d'induction sérique du CFF ont été testés: des souris C57BL/6 infectées par la souche de P. chabaudi adami AS, des souris C57BL/6 inoculées avec BCG + LPS, et des souris BALB/c infectées respectivement avec les souches de P. chabaudi adami DS ou DK. L'activité inhibitrice la plus prononcée a été observé à partir du sérum prélevé chez les souris C57BL/6 infectées par la souche de P. chabaudi adami AS. Le sérum issu de ce modèle a donc été utilisé pour la suite des analyses de CFF. Nous avons déterminé que l'activité de CFF ne provient pas des protéines du complément et que CFF est inactivé lorsque le sérum est bouilli à 100oC. Le fractionnement du sérum par chromatographie d'exclusion nous a permis de déterminer que CFF est éluée dans les fractions protéiques allant de 20 kDa à 80 kDa. Le sérum a ensuite été soumis à une colonne d'affinité IgY afin d'y dépléter les protéines majoritaires. Suite à cette déplétion, nous avons déterminé que l'activité de CFF est préservée uniquement dans la fraction contenant les protéines sériques de faible abondance (LAP; « low abundance protein »). Nous avons donc analysé la fraction LAP du sérum induit pour CFF par spectrométrie de masse de type MALDI et LC-QToF, puis comparé son profil protéique à celui de la fraction LAP de sérum issu de souris naïves. Ces profils protéiques révèlent qu'un total de 68 protéines sont soit surexprimées, soit exclusives au sérum démontrant une activité CFF. De plus, l'analyse qualitative nous a permis d'identifier une protéine candidate potentiel pour CFF : la gélatinase de neutrophile associée à la lipocaline (NGLA; « neutrophil gelatinase-associated lipocalin »). En concluant, nous avons établi un modèle d'induction sérique de CFF, avons caractérisé certaines de ses propriétés physiques et avons identifié, par l'entremise de la protéomique, NGLA en tant que candidate potentielle de CFF.

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El-Shehabi, Fouad. "Characterization of novel biogenic amine receptors in the human bloodfluke «Schistosoma mansoni»." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=86610.

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The genome of the human bloodfluke Schistosoma mansoni encodes 18 putative biogenic amine-like G-protein-coupled receptors (GPCRs). These receptors are potential targets for the development of antischistosomal drugs. One of these sequences, SmGPR-1 (formerly SmGPCR), was previously cloned and was identified as a histamine receptor. In this study, we expanded the functional analysis of SmGPR-1 by studying its expression and tissue distribution both at the RNA and protein levels in different developmental stages of the parasite. In the second part of the study, we cloned and characterized two structurally related receptors, named SmGPR-2 and SmGPR-3. Bioinformatics analyses showed that the three receptors are members of a new clade of biogenic amine GPCRs and are characterized in part by the absence of a highly conserved aspartate (Asp3.32) of the third transmembrane domain. Like SmGPR-1, our first cloned receptor, SmGPR-2, was activated by histamine and its developmental expression at the mRNA level was similar to that of SmGPR-1, both receptors being upregulated in young schistosomula. However, their tissue localization was different. SmGPR-1 was enriched in the tegument, subtegumental musculature and the suckers, whereas SmGPR-2 was associated with neurons of the subtegumental plexuses. The distribution of these receptors correlated with that of histaminergic neurons, which were also detected in the subtegumental neuronal plexuses, the innervation of the suckers, elements of the central nervous system and transverse commissures. These studies suggest that histamine is an important neurotransmitter system in schistosomes. The third receptor investigated in this study, SmGPR-3, was not responsive to histamine but rather was found to have broad specificity for catecholamines, particularly dopamine and related metabolites. In vitro assays of cultured schistosomula revealed that many of the ligands that interact with SmGPR-3 also have strong effects on larval motilit
Au génome de Schistosoma mansoni, un parasite sanguin de l'homme, on retrouve 18 récepteurs putatifs à amine biogène couplés aux protéines G (RCPG). Ces récepteurs ont un potentiel thérapeutique contre les infections aux schistosomes. La séquence SmGPR-1 (anciennement SmGPCR) a déjà été clonée et identifiée comme un récepteur à l'histamine. Une analyse fonctionnelle plus poussée de SmGPR-1 est l'objet de cette thèse. L'analyse de taux d'ARNm et de protéines à différents stades de développement du parasite a servi à l'étude de l'expression et la répartition tissulaire de SmGPR-1. Deux récepteurs similaires, de par leur structure, le SmGPR-2 et le SmGPR-3 ont été identifiés, clonés et caractérisés lors de cette étude. Suite à des analyses bioinformatiques, ces trois récepteurs ont révélé leur appartenance à une nouvelle variante de récepteurs à amine biogène couplés aux protéines G caractérisés par l'absence d'aspartate conservé (Asp3.32) dans le troisième domaine transmembranaire. Tout comme SmGPR-1, le récepteur SmGPR-2 est activé par l'histamine, et l'expression de l'ARNm est similaire à celle de SmGPR-1, les deux récepteurs étant régulés à la hausse chez les jeunes schistosomes. Toutefois, ils sont localisés à différents endroits, SmGPR-1 se retrouve dans le tégument, la musculature subtégumentaire et les ventouses, tandis que SmGPR-2 est associé aux plexus nerveux subtégumentaires. La localisation de ces récepteurs est similaire à celle des neurones histaminergiques que l'on retrouve dans les plexus nerveux subtégumentaires, l'innervation des ventouses, dans certains éléments du système nerveux central et les commissures transversales. Il semblerait que l'histamine soit un important système neurotransmetteur du schistosome. Le troisième récepteur identifié, SmGPR-3, n'est pas activé par l'histamine, mais semble démontrer une spécificité étendue aux catécholamines et tout particuli

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Sen, Rajashree. "Structure-function analysis of RNA editing ligases and their interacting protein partners in the editosome complex of «Trypanosoma brucei»." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=95053.

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Trypanosoma brucei is a parasite that causes the vector-borne disease African sleeping sickness. The mitochondrial mRNAs of T. brucei undergo post-transcriptional RNA editing to make mature, functional mRNAs. The final step of this process is catalyzed by the essential ligase, Kinetoplastid RNA Editing Ligase 1(KREL1) and closely related KREL2. This study is an in vitro characterization of interaction of KREL1 and KREL2 with binding partners KREPA2 and KREPA1, respectively, using full-length, truncated and point-mutated ligases. We have shown a strong, specific stimulatory effect of the interacting partners on catalytic activity of the ligases. We have narrowed the region of contact to fifty-nine C-terminal residues for KREL1 and forty-five for KREL2. Finally we have identified the N-terminal residues F206, T264 and Y275 and C-terminal K405 on KREL1 as critical for catalytic activity as well as interaction with KREPA2. K424 and the KWKE (441-444) stretch possibly co-ordinate KREPA2 interaction during adenylylation.
Trypanosoma brucei est un parasite responsable en Afrique de la maladie du sommeil, une maladie à transmission vectorielle. Les ARNm mitochondriaux de T. Brucei subissent l'édition de l'ARN au niveau post-transcriptionnel pour produire des ARNm matures et fonctionnels. L'étape finale de ce processus est catalysée par la ligase essentielle KREL1 (Kinetoplastid RNA Editing Ligase 1) et celle étroitement liée, KREL2. Cette étude est une caractérisation in vitro de l'interaction de KREL1 et de KREL2 avec les partenaires de liaison KREPA2 et KREPA1 respectivement, en utilisant les séquences complètes, tronquées et mutées des ligases. Nous avons montré un effet stimulateur spécifique prononcé des partenaires interagissant, sur l'activité catalytique des ligases. Nous avons rétréci la région de contact à cinquante neuf acides aminés à l'extrémité C-terminale pour KREL1 et quarante cinq pour KREL2. Finalement, nous avons identifié les acides aminés F206, T264 et Y275 à l'extrémité N-terminale et K405 à l'extrémité C-terminale de KREL1 comme crucial pour l'activité catalytique aussi bien que pour l'interaction avec KREPA2. Les acides aminés K424 et KWKE (441-444) s'étendent éventuellement pour coordonner l'interaction de KREPA2 au cours de l'adénylation.

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Rao, Vijayaraghava. "Characterization of novel ligand-gated chloride channel subunits from «Haemonchus contortus»." Thesis, McGill University, 2010. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=95130.

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Ligand-gated chloride channels (LGCCs) are key components that form the inhibitory neurotransmission system in animals. Nematodes possess LGCCs that are gated by unique ligands such glutamate, serotonin and acetylcholine. Higher living forms such as mammals are not known to possess similar receptors. Hence nematodes can be deemed to comprise a phylum with a divergent inhibitory neurotransmission system. Based on this premise, the current project aimed to better understand the inhibitory nervous system of the parasitic nematode, Haemonchus contortus through the characterization of novel LGCC subunits and the localization of relevant ligands believed to function as inhibitory neurotransmitters. The first novel LGCC subunit gene to be isolated was named Hco-GGR-3 (previously named as HcGGR3). Electrophysiological analyses of this subunit in Xenopus laevis oocytes revealed the homomeric assembly of the channel which was predominately gated by dopamine (DA). Immuno-staining of H. contortus adult worms using antibodies raised against a peptide exclusive to Hco-GGR-3 showed that this subunit localized to deirid (cervical papilla) socket and sheath cells. Gender specific differences in localization of this subunit were also observed. In addition, a single nucleotide polymorphism located in the 3' untranslated region (UTR) of Hco-ggr-3 was found to be associated with the selection for resistance towards macrocyclic lactones (MLs) moxidectin (MOF) and ivermectin (IVM) in H. contortus. A second amine-gated chloride channel gene called Hco-lgc-55 was also isolated. Electrophysiology of this subunit revealed that this channel was gated mainly by tyramine (TA) [EC50 5.8 ± 1.0 μM (n=5)] and a lesser extent by dopamine (DA) and octopamine (OA). Semi-quantitative reverse transcription polymerase chain reaction (SqRT-PCR) showed the presence of mRNA for Hco-lgc-55 in all the life-cycle stages of the parasite. A detailed examination of the localization and characterization o
Les canaux chlorures ligand-dépendants (CCLDs) sont la composante clef du système d'inhibition de la neurotransmission chez les animaux. Les nématodes possèdent des CCLDs qui sont activés par des ligands uniques tels que le glutamate, la sérotonine et l'acétylcholine. Les mammifères ne possèdent pas ce type de récepteurs. Il est possible d'émettre l'hypothèse que le phylum des nématodes a un système d'inhibition de la neurotransmission divergent. Basé sur cette caractéristique, le projet a pour objectif de mieux comprendre le système nerveux inhibiteur chez le nématode parasite, Haemonchus contortus, en caractérisant de nouvelles sous-unités de CCLD, et en localisant des ligands valables, connus pour fonctionner comme neurotransmetteur inhibiteur. La première nouvelle sous-unité du gène de CCLD à avoir été isolée, a été appelé Hco-GGR-3 (précédemment nommé HcGGR3). Les analyses électrophysiologiques de cette sous-unité, réalisées dans les ovocytes de Xenopus laevis, ont permis d'identifier un assemblage homomérique de ce canal qui est majoritairement dépendant de la dopamine (DA). L'immunocoloration de vers adultes d'H. contortus, faite à partir d'anticorps spécifiques à un peptide exclusif à Hco-GGR3, a permis de montrer que cette sous-unité était localisée au niveau des ports des deirids (papille cervicale) et des cellules de gaines. Il a été aussi observé qu'il y avait une différence de localisation de cette sous-unité en fonction du genre des vers. De plus, un polymorphisme mononucléotidique au niveau de la région 3' non transduite (UTR) de Hco-ggr3 s'est avéré être associé à une sélection pour la résistance aux lactones macrocycliques (LM) - la moxidectine (MOF) et l'ivermectine (IVM) - chez H. contortus. Un second gène d'un canal chlorure dépendant d'un acide aminé appelé Hco-lgc-55 a aussi été isolé. L'électrophysiologie de cette sous-unité a permis de montrer que ce canal était maj

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Rioux, Marie-Claire. "A study of the proteomics of fasciolosis." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=106286.

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Fasciolosis is an economically important veterinary parasitic disease. Of the two causative agents, Fasciola hepatica and Fasciola gigantica, F. hepatica has a greater ability to effectively establish a primary infection and resist the host defences. Certain host species, such as cattle, are more resistant to reinfection than others, such as sheep. In order to gain a greater understanding of the host response to infection, proteomic analyses of sera from sheep and cattle infected with F. hepatica were undertaken. Twenty-six indicators of infection were validated by SELDI-TOF mass spectrometry (MS) in sheep with a single-dose F. hepatica infection. Two of these markers were identified and their increase in the chronic stage of infection was validated using Western blot analysis. SELDI-TOF MS profiling of sera from trickle-infected cattle did not provide descriptive information, but tandem MS analysis of immunodepleted sera provided a more descriptive view of the host-parasite interaction. This technique was sufficiently sensitive to detect markers of inflammation during the acute stage of infection and markers of liver fibrosis during the chronic stage of infection, but was not sufficiently sensitive to detect parasite proteins. Finally, the excretory-secretory products (ESP) of F. hepatica and F. gigantica were profiled. The similarities between the two species were greater than the similarities between newly excysted juveniles (NEJ) and adults. The most notable differences between NEJ and adults were the profile of proteases released and the specific isotypes released by the parasites. NEJ expressed relatively equal amounts of cathepsin L, B, and legumain, whereas adults expressed predominantly cathepsin L. NEJ- and adult-specific cathepsin L clades were identified as well as a potential F. gigantica NEJ-specific cathepsin L clade. Antioxidant defence enzyme levels were higher in adult ESP than NEJ ESP, with higher relative abundance in F. gigantica than F. hepatica. The analysis suggests that stage-specific expression and isotype diversity should be considered when developing a vaccine targeted to the early stage of infection and when studying broad-spectrum chemotherapeutic targets. These studies contribute to the understanding of the basic biology of the causative agents of fasciolosis and the use of proteomics in studying host-parasite interactions.
La fasciolase est une infection vétérinaire importante. Entre les deux agents causals, Fasciola hepatica et Fasciola gigantica, f. hepatica a une meilleure capacité pour établir une infection primaire et pour résister aux défenses de l'hôte. Certaines espèces hôtes, tels que les bovins, résistent une seconde infection mieux que d'autres espèces, tels que les moutons. Afin de mieux comprendre la réaction de l'hôte pendant l'infection, des analyses protéomiques de sérums de moutons et de bovins affectés par f. hepatica ont été entreprises. Vint-six marqueurs d'infection ont été validés par spectrométrie de masse de temps de vol à désorption-ionisation laser potentialisée par surface (SM TDV-DILPS) chez les moutons avec une seule dose infectieuse de f. hepatica. Deux de ces marqueurs ont été identifiés et leur hausse dans la phase chronique de l'infection a été validée par buvardage de western. Le profil SM TDV-DILPS de bovins infectés à plusieurs reprises n'a pas fourni des détails descriptifs, mais une analyse SM en tandem de sérums immunodéplétés a fourni un portrait descriptif de l'interaction hôte-parasite. Cette technique était suffisamment sensible pour détecter des marqueurs d'inflammation pendant la phase aigüe de l'infection et des marqueurs de la fibrose hépatique pendant la phase chronique de l'infection, mais n'était pas suffisamment sensible pour détecter des protéines parasitaires. Enfin, les produits d'excrétion-sécrétion (PES) de f. hepatica et f. gigantica ont été profilées. Les deux espèces partageaient plus de similitudes que parmi les phases de juvéniles nouvellement excystés (JNV) et des adultes. Les différences les plus notables entre les JNV et les adultes étaient le profil des protéases et les isotypes de ces protéases retrouvés. Les montants de cathepsine L, B et de legumain chez les JNV étaient relativement égaux, tandis que la majorité des protéases chez les adultes étaient cathepsine L. Des clades de cathepsine L spécifiques aux JNV et aux adultes ont été identifiés ainsi qu'un clade potentiellement spécifique aux JNV de f. gigantica. Les niveaux d'enzymes antioxydants de défense dans les PES étaient plus élevés dans chez les adultes que les JNV, ainsi qu'une abondance plus élevées chez f. gigantica que f. hepatica. Ces analyses suggèrent que l'expression des protéines spécifique aux phases de développement et la diversité des isotypes devraient être considérées lors de l'élaboration d'un vaccin ciblé à un stade précoce de l'infection et lors du développement de cibles chimiothérapeutiques à large spectre. Ces études contribuent aux connaissances fondamentales des agents causals de fasciolase et l'usage d'outils protéomiques dans l'étude des interactions hôte-parasite.

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Books on the topic "Parasitology (biology)"

1

1909-, Noble Elmer Ray, and Noble Elmer Ray 1909-, eds. Parasitology: The biology of animal parasites. 6th ed. Philadelphia: Lea & Febiger, 1989.

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1951-, Grieve Robert Burton, Demaree Richard S. 1942-, and Marquardt William C. 1924-, eds. Parasitology and vector biology. 2nd ed. San Diego, Calif: Harcourt Academic, 2000.

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Advances in parasitology. London: Academic Press, 2009.

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Molecular parasitology. Milton Keynes: Open University Press, 1990.

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Hyde, John E. Molecular parasitology. Milton Keynes: Open University Press, 1990.

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Molecular parasitology. New York: Van Nostrand Reinhold, 1990.

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Hyde, John E. Molecular parasitology. Buckingham: Open University Press, 1990.

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1933-, Fried Bernard, and Graczyk Thaddeus K, eds. Advances in trematode biology. Boca Raton: CRC Press, 1997.

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1954-, Tschudi Christian, and Pearce Edward J. 1958-, eds. Biology of parasitism. Boston: Kluwer Academic, 2000.

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E, Hyde John, ed. Protocols in molecular parasitology. Totowa, N.J: Humana Press, 1993.

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Book chapters on the topic "Parasitology (biology)"

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Loker, Eric S., and Bruce V. Hofkin. "Parasites and Conservation Biology." In Parasitology, 367–418. 2nd ed. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9780429277405-8.

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Loker, Eric S., and Bruce V. Hofkin. "Evolutionary Biology of Parasitism." In Parasitology, 295–365. 2nd ed. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9780429277405-7.

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Gould, S. B., G. Kusdian, V. Zimorski, and W. F. Martin. "Trichomonads and Their Cell Biology." In Encyclopedia of Parasitology, 2847–52. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-43978-4_3257.

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Gould, S. B., G. Kusdian, V. Zimorski, and W. F. Martin. "Trichomonads and Their Cell Biology." In Encyclopedia of Parasitology, 1–5. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27769-6_3257-2.

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"Parasitology." In Encyclopedia of Systems Biology, 1632. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_101107.

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Théodoridès, Jean. "Parasitology of Marine Zooplankton." In Advances in Marine Biology, 117–77. Elsevier, 1989. http://dx.doi.org/10.1016/s0065-2881(08)60189-3.

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Handman, Emanuela. "Cell Biology of Leishmania." In Advances in Parasitology, 1–39. Elsevier, 1999. http://dx.doi.org/10.1016/s0065-308x(08)60229-8.

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Maheshwari, Nanda. "General Biology." In Clinical Microbiology and Parasitology (For DMLT Students), 1. Jaypee Brothers Medical Publishers (P) Ltd., 2016. http://dx.doi.org/10.5005/jp/books/12721_2.

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"Chromosomes Ends and Telomere Biology of Trypanosomatids." In Frontiers in Parasitology, edited by Miguel Angel Chiurillo, Cristiane Regina Antonio, Marjorie Mendes Marini, Renata Torres de Souza, and José Franco da Silveira, 104–33. BENTHAM SCIENCE PUBLISHERS, 2017. http://dx.doi.org/10.2174/9781681084053117010006.

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Pike, A. W., and S. L. Wadsworth. "Sealice on Salmonids: Their Biology and Control." In Advances in Parasitology, 233–337. Elsevier, 1999. http://dx.doi.org/10.1016/s0065-308x(08)60233-x.

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Conference papers on the topic "Parasitology (biology)"

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Aznar-Avendaño, Francisco Javier, Guillermo Albert-García, Pedro Barón-Rodríguez, Saúl Bernat-Ponce, Michael Butler-Margalef, Raúl Ceballos-Nagore, Raimon Cuxart-Erruz, et al. "TEACHING PARASITOLOGY IN BIOLOGY DEGREES: FROM SUBJECTS TO PRINCIPLES." In 16th International Technology, Education and Development Conference. IATED, 2022. http://dx.doi.org/10.21125/inted.2022.0726.

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Neculiseanu, Zaharia. "Biologia scarabaeidelor Cetonia aurata (Linnaeus) și Protaetiaaffinis affinis (Andersch) (Coleoptera, Scarabaeidae) in condițiile Republicii Moldova." In International symposium ”Actual problems of zoology and parasitology: achievements and prospects” dedicated to the 100th anniversary from the birth of academician Alexei Spassky. Institute of Zoology, Republic of Moldova, 2018. http://dx.doi.org/10.53937/9789975665902.73.

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This article presents results of biology research of two species of Scarabaeidae under the conditions of the Republic of Moldova. The Cetonia aurata development cycle takes place within two years, is a monovoltine spring-summer breeder, hibernates in the adultsand sometime in the larval stage. The adults and larvae lives in plant composts, in decomposed foliage, in rotten roots of plants. Adults sometimes attack inflorescences of fruit trees, so they can be considered pests of orchards, but some larvae live in the soil, consume plant remains and plant composts, so this saprofage species is considered and useful. The second species Protaetia affinis affinis is a mesophyla species with summer-autumn reproduction type, hibernates in the adult stage and larvae, lives in deciduous and semi-degraded vegetal debris from deciduous forests, forests strips, orchards. Species do not cause damage to forestry and agriculture.

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Silva, Larissa Martins da. "O ENSINO DAS PARASITOSES HUMANAS ATRAVÉS DO SITE WORDWALL: UMA VISÃO DOS ESTUDANTES DA ESCOLA ESTADUAL MONSENHOR HONÓRIO - PENDÊNCIAS/RN." In II Congresso Brasileiro de Parasitologia Humana On-line. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/conbrapah/29.

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Introdução: Com o fechamento das escolas diante do cenário emergencial causado pela pandemia do COVID-19, professores tiveram que recorrer a diversas estratégias para conduzirem o processo de ensino-aprendizagem dos alunos por meio do ensino remoto. Com isso, uma das plataformas disponíveis para envolver os conteúdos da Biologia como a parasitologia humana de maneira interativa e lúdica é o chamado site Wordwall que permite criar diversas atividades personalizadas como: questionários, competições, jogos de palavras e muito mais. Objetivo: Conhecer a visão dos alunos sobre o uso de atividade criada através do site Wordwall diante os estudos das principais parasitoses humanas. Material e métodos: Para o alcance do objetivo proposto, após as aulas teóricas sobre as principais parasitoses humanas (amebíase, ascaridíase, doença de chagas, elefantíase, e outras) foi aplicado a um total de 63 estudantes da Escola EstadualMonsenhor Honório - Pendências/RN, a atividade do Wordwall que era baseada em um questionário de múltipla escolha com imagens com tempo, linhas da vida e uma rodada bônus com pontuações sorteadas pelo participante. Posteriormente, eles deixaram suas opiniões sobre a atividade através de perguntas fechadas através do Google forms e que foi analisada quantitativamente. Resultados: 100% dos alunos apontaram que gostaram da atividade criada no Wordwall; 92% marcaram que conseguiram responder corretamente todas as perguntas sobre as principais parasitoses humanas. 100% indicaram que esse tipo de atividade facilita na revisão do ciclo das doenças, o agente causador e os sintomas. 89% afirmaram que confundem muito as parasitoses humanas e o fato da atividade estimular a competição ajuda a se concentrarem e aprenderem mais rápido. Por fim, 100% assinalaram que gostariam de mais atividades criadas no site Wordwall para o estudo de parasitologia. Conclusão: Os estudantes demonstraram que possuem uma visão positiva diante do uso do Wordwall para o estudo das principais parasitoses humanas, permitindo revisarem, fazerem associações entre as imagens correspondentes às doenças e suas informações e ainda que ficaram mais entusiasmados pelo estudo da parasitologia ao competirem entre si. Portanto, o site é uma estratégiaque pode contribuir no processo de ensino-aprendizagem da parasitologia nas aulas de Biologia.

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Medeiros, Mildred Ferreira, Victor Geremias Ribeiro, and Louise Calil Deterling. "PROPOSTA DE ATUAÇÃO DO BIÓLOGO NA EDUCAÇÃO EM SAÚDE DA COMUNIDADE SOBRE A DOENÇA DE CHAGAS SOBRE O RISCO DE CONTAMINAÇÃO HUMANA POR TRYPANOSSOMA CRUZI A PARTIR DA INGESTÃO DE POLPA DE AÇAÍ OU CALDO DE CANA CONTAMINADOS." In II Congresso Brasileiro de Parasitologia Humana On-line. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/conbrapah/36.

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Introdução: A ingestão de polpa de açaí ou caldo de cana contaminados com fezes de triatomíneos ou triatomíneos contaminados com o parasita Trypanossoma cruzi triturados com alimentos se tornou a principal causa de contaminação humana por Doença de Chagas, um grave problema de saúde pública em algumas regiões do Brasil. Objetivo: Diante deste cenário, o presente estudo teve como objetivo geral esclarecer quais são as possibilidades de atuação do biólogo junto às equipes multiprofissionais de saúde baseadas nas competências do biólogo asseguradas pelas resoluções e normativas do Conselho Federal de Biologia, descrevendo também as características do parasita e as formas de transmissão. Metodologia: Optou-se por realizar um estudo com abordagem qualitativa descritiva exploratória realizado a partir de análise de dados coletados por levantamento bibliográfico sobre o tema na Biblioteca Virtual de Saúde (BVS). Resultados: A análise dos dados coletados permitiu identificar que o biólogo pode integrar equipes multiprofissionais de saúde para planejamento e realização de atividades educativas sobre o tema direcionadas para a comunidade, visando multiplicar o conhecimento para prevenção da ocorrência de casos e de surtos da doença através da ingestão de alimentos contaminados. Ainda assim, foi possível identificar que o biólogo pode atuar na vigilância sanitária, na vigilância epidemiológica, e na realização de exames laboratoriais para diagnóstico da doença, e integrando pesquisas sobre tratamentos e para desenvolvimento de vacinas para doença, e que estas competências estão regulamentadas pela resolução do Conselho Federal de Biologia. Conclusão: O presente estudo permitiu sugerir esta inserção ativa do biólogo nesta área importante para promoção da saúde pública.

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Ferreira, Leobruno Revil Torres, Lydyana De Jesus Boás Camberimba, Vânia Maria Carvalho Jansen, Lívia Mariane Castelo Branco Reis Coutinho De Oliveira, and Noricka Gurjão Noronha De Melo. "REVISÃO DE LITERATURA: ESQUISTOSSOMOSE E A BAIXADA MARANHENSE." In II Congresso Brasileiro de Parasitologia Humana On-line. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/conbrapah/10.

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Introdução: A esquistossomose é uma doença parasitária diretamente relacionada ao saneamento precário da região ao qual o indivíduo convive, a mesma é causada pelo Schistosoma mansoni. A pessoa se contamina quando entra em contato com água doce onde existam caramujos infectados pelos vermes causadores da doença. Objetivo: Descrever os principais motivos da esquistossomose ser mais prevalente na baixada maranhense do que em outras localidades do Estado. Métodos: Para tanto, foi realizado um levantamento bibliográfico de 22 artigos científicos nos diretórios Google Acadêmico, Scientific Electronic Library Online (SciELO) e PubMed, sendo utilizados 16 deles para embasar o presente trabalho. Ao pesquisar utilizou-se os seguintes descritores: esquistossomose e maranhão. Utilizando como método de exclusão artigos com temas mais amplos que fugiam a ideia do central do assunto que essa doença parasitária no Estado do Maranhão. Resultados: A esquistossomose por ser uma doença favorável de lugares alagadiços, a Baixada Maranhense fornece o ambiente adequado para essa ocorrência. De acordo com o Ministério da Saúde, foram confirmados 119 casos de esquistossomose no estado maranhense. Em São Bento, município da Baixada Ocidental Maranhense, possui a maior incidência. Um estudo feito nessa cidade pelo departamento de química e biologia da UEMA (universidade Estadual do Maranhão)a maioria dos casos de indivíduos positivos ocorreram em pescadores do sexo masculino que estavam em contado com a doença. A educação precária e o saneamento básico de baixa qualidade são fatores que favorecem ainda mais a disseminação do transmissor da enfermidade. Deste modo, a educação sanitária a respeitos das formas de transmissão e controle da doença se faz necessário. Conclusão: Por ser uma doença de hospedeiros de água doce que vivem em regiões alagadiças, a doença encontrou o melhor habitat na Baixada maranhense, onde possui vastas áreas de alagamento. Unindo esses fatores a desinformação de grande parte da população, ocorre o casamento perfeito para a propagação e perpetuação do ciclo reprodutivo da doença

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Moldovan, Anna, Ion Toderaș, and Natalia Munteanu-Molotievskiy. "Noi agenți bacterieni de control biologic al insectelor dăunătoare in Republica Moldova." In International symposium ”Actual problems of zoology and parasitology: achievements and prospects” dedicated to the 100th anniversary from the birth of academician Alexei Spassky. Institute of Zoology, Republic of Moldova, 2018. http://dx.doi.org/10.53937/9789975665902.70.

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Modern agriculture faces numerous problems, many of which are caused by the excessive use of synthetic pesticides to control pests. Development of a sustainable agriculture system is a priority for the Republic of Moldova, the main objectives being food security, protection of environment, support the competitiveness of local farmers on national and international market. Biological control proved to be a successful approach to the sustainable management of harmful insects. Thus, it is necessary to make continuous efforts to address the demand of business and national economy in environmentally friendly pesticide products. This study aimed to highlight new agents for biological control of insect pests based on local Bacillus thuringiensis (Bt) strains. Highlighted strains show promising results having a high insecticidal activity against lepidopteran (Lymantria dispar, Cydia pomonella and Archips rosana) and coleopteran (Neocoenorhinidius pauxillus, Phyllobius oblongus and Sitona lineatus) pest species. It therefore will allow local production of biopesticides, which will significantly reduce the final cost of the product, making it more accessible to farmers. Use of local Bt strains will also help avoid the ecological risks associated with the introduction of new organisms into ecosystems.

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Carneiro, Luana Gomes, and Maria José Paes. "ESTUDO PRELIMINAR SOBRE A RELEVÂNCIA DA FORMAÇÃO CONTINUADA PARA PROFESSORES DE BIOLOGIA SOBRE O TEMA “DOENÇAS NEGLIGENCIADAS PARASITÁRIAS”." In II Congresso Brasileiro de Ciências Biológicas On-line. Revista Multidisciplinar de Educação e Meio Ambiente, 2021. http://dx.doi.org/10.51189/rema/1222.

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Introdução: Doenças Negligenciadas (DN) prevalecem em condições de vulnerabilidade social, não recebendo a devida atenção do poder público. As DN incluem agentes etiológicos diversos, incluindo parasitas, que formam um grupo específico, as Doenças Negligenciadas Parasitárias (DNP), que atingem um alto percentual da população brasileira. No ensino médio a educação em saúde é atrelada à disciplina Biologia, o que torna o ensino nesta área um importante aliado na formação cidadã, oportunizando aos estudantes e professores momentos de interação que podem vir a contribuir para a redução dos impactos devido à disseminação de DNP. Objetivos: O objetivo deste trabalho foi avaliar, em caráter preliminar, o conhecimento básico de professores de biologia do ensino médio e apontar a importância de disponibilizar programas de formação continuada para esses profissionais. Materiais e Métodos: Os dados foram obtidos a partir de um questionário estruturado com perguntas abertas e fechadas, que foi respondido por 23 professores de Biologia do ensino médio. Resultados: O termo “doenças negligenciadas” foi reconhecido por 74% dos respondentes, porém somente 4% destes associaram as DN à falta de higiene ou saneamento e 17% à pobreza ou vulnerabilidade social, mas 39% fizeram a substituição da palavra “negligenciada” por “esquecida” ou sinônimos, demonstrando um conhecimento superficial do conceito. Para apenas 17,4% dos respondentes a formação em parasitologia na graduação foi excelente, o que preocupa, dada a importância do tema. A maioria dos respondentes, 70%, fez corretamente a associação entre DN e parasitoses. A abordagem de DNP é ineficiente ou ausente nos currículos de ensino médio segundo 65,2% dos respondentes, somando-se esse dado à abordagem superficial presente nos livros didáticos, é possível perceber que o tema pode não estar recebendo a devida importância também na escola. Conclusão: Os resultados apontam para uma necessidade de formação continuada para os docentes, especialmente aqueles que atuam em áreas onde a incidência de DNP é alta, dando a estas ferramentas que permitam aprimorar suas práticas de ensino trabalhando o tema dentro de seu planejamento de forma ampla e eficiente beneficiando a todos.

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Moldovan, Anna. "Perspective de dezvoltare a agenților bacterieni de control biologic al insectelor dăunătoare in Republica Moldova." In International symposium ”Actual problems of zoology and parasitology: achievements and prospects” dedicated to the 100th anniversary from the birth of academician Alexei Spassky. Institute of Zoology, Republic of Moldova, 2018. http://dx.doi.org/10.53937/9789975665902.71.

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