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Journal articles on the topic 'Parenchymal'

Author: Grafiati

Published: 5 June 2025

Last updated: 2 August 2025

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1

Kim, Sung-Woo. "Ultrasonographic Findings of Thyroid Parenchymal Disease." Clinical Ultrasound 9, no. 1 (2024): 25–30. http://dx.doi.org/10.18525/cu.2024.9.1.25.

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Thyroid parenchymal disease is an inflammatory disease that occurs in the thyroid parenchyma due to autoimmunity or infection. The differential diagnosis of thyroid parenchymal disease is based on clinical manifestation, physical examination, and serological findings. However, ultrasonography of thyroid has also a role in the diagnosis of thyroid parenchymal disease. This review describes common findings of ultrasonography in each thyroid parenchymal disease.

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Yokel, Robert A. "Nanoparticle brain delivery: a guide to verification methods." Nanomedicine 15, no. 4 (2020): 409–32. http://dx.doi.org/10.2217/nnm-2019-0169.

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Many reports conclude nanoparticle (NP) brain entry based on bulk brain analysis. Bulk brain includes blood, cerebrospinal fluid and blood vessels within the brain contributing to the blood–brain and blood–cerebrospinal fluid barriers. Considering the brain as neurons, glia and their extracellular space (brain parenchyma), most studies did not show brain parenchymal NP entry. Blood–brain and blood–cerebrospinal fluid barriers anatomy and function are reviewed. Methods demonstrating brain parenchymal NP entry are presented. Results demonstrating bulk brain versus brain parenchymal entry are cla

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Konova, A. V. "The interrelation between parenchymal thickness of the affected kidney and its morphological changes in hydronephrosis." Siberian Medical Review 6 (2022): 33–37. http://dx.doi.org/10.20333/25000136-2022-6-33-37.

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Aim of study. To study the relationship between the thickness of the parenchyma of the aff ected kidney and the nature of its morphological changes. Material and methods. Archival medical records of 350 patients operated on for congenital hydronephrosis within the period 1990-2020 were processed. Th e age of patients at the time of surgery ranged from two months to 18 years. Based on the protocols of ultrasound examination of the kidneys before surgery, the parenchymal thickness defi cit was calculated. Morphological analysis of parenchymal tissue was carried out on the basis of its histologic

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Nomani, Laila, Claudiu V. Cotta, Eric D. Hsi, Judith A. Ferry, and James R. Cook. "Extranodal Marginal Zone Lymphoma of the Central Nervous System Includes Parenchymal-Based Cases With Characteristic Features." American Journal of Clinical Pathology 154, no. 1 (2020): 124–32. http://dx.doi.org/10.1093/ajcp/aqaa032.

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Abstract Objectives To define the clinicopathologic features of extranodal marginal zone lymphoma (EMZL) of the central nervous system (CNS), including cases arising in CNS parenchyma, which have been reported only rarely. Methods Twelve cases of CNS EMZL were identified, including 5 based in CNS parenchyma and 7 nonparenchymal cases arising in dura or choroid plexus. Results Histologically, parenchymal cases were perivascular infiltrates without a dominant lymphoid mass, whereas nonparenchymal cases were masses of small lymphocytes. Plasma cells were a larger component of the infiltrate in pa

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Konova, A. V. "Dynamics of renal parenchymal thickness in hydronephrosis patients before and after surgery." Siberian Medical Review 5 (2021): 61–66. http://dx.doi.org/10.20333/25000136-2021-5-61-66.

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Aim of study. To reveal changes in renal parenchymal thickness in hydronephrosis patients before and after surgery depending on the patient’s age. Materials and methods. Archived medical histories of 350 patients after surgery for congenital hydronephrosis within 1990-2020 were studied. The age of patients at the moment of surgery varied from one month to 18 years. The dynamics of change in the parenchymal layer thickness of the impaired kidney was evaluated based on ultrasound protocols of kidney scanning before and after the surgery. Results. The maximum decrease in renal parenchyma before s

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Henning, Erica C., Lawrence L. Latour, and Steven Warach. "Verification of Enhancement of the CSF Space, not Parenchyma, in Acute Stroke Patients with Early Blood—Brain Barrier Disruption." Journal of Cerebral Blood Flow & Metabolism 28, no. 5 (2007): 882–86. http://dx.doi.org/10.1038/sj.jcbfm.9600598.

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Enhancement on post-contrast fluid-attenuated inversion recovery (FLAIR) images after acute stroke has been attributed to early blood—brain barrier disruption. Using an estimate of parenchymal volume fraction and the apparent diffusion coefficient (ADC), we investigated the relative contributions of cerebral spinal fluid (CSF) and parenchyma to enhancement seen on postcontrast FLAIR. Enhancing regions were found to have low parenchymal volume fractions and high ADC values, approaching that of pure CSF. These findings suggest that contrast enhancement on FLAIR occurs predominately in the CSF sp

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Durdona, Mirmakhmudovna Alikarieva. "Morphological and Anatomical Features of the Structure of Vegetative and Generative Organs of Lycium Chinense Mill. and Lycium Barbarum L. Solanaceae Juss. in the Conditions of Uzbekistan." RA JOURNAL OF APPLIED RESEARCH 08, no. 02 (2022): 131–46. https://doi.org/10.5281/zenodo.6131583.

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ABSTRACT: The characteristics of <em>Lycium chinens</em><em>e</em> Mill and <em>Lycium barbarum </em>L., species, taxonomy, origin and use in medicineare given. The adaptation of these plants in the conditions of the Botanical Garden of Tashkent, as well as in the conditions of the Namangan region, was studied. The morphological and anatomical structures of two species of the genus <em>Lycium</em> have been studied. The morphology and structure of vegetative and generative organs, which differ from each other in leaf shape and venation, are described. Leaf cells a

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McCall, Anthony L., Antonia M. Van Bueren, Valerie Nipper, Melissa Moholt-Siebert, Hall Downes, and Nikola Lessov. "Forebrain Ischemia Increases Glut1 Protein in Brain Microvessels and Parenchyma." Journal of Cerebral Blood Flow & Metabolism 16, no. 1 (1996): 69–76. http://dx.doi.org/10.1097/00004647-199601000-00008.

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Glucose transport into nonneuronal brain cells uses differently glycosylated forms of the glucose transport protein, GLUT1. Microvascular GLUT1 is readily seen on immunocytochemistry, although its parenchymal localization has been difficult. Following ischemia, GLUT1 mRNA increases, but whether GLUT1 protein also changes is uncertain. Therefore, we examined the immunocytochemical distribution of GLUT1 in normal rat brain and after transient global forebrain ischemia. A novel immunocytochemical finding was peptide-inhibitable GLUT1 immunoreactive staining in parenchyma as well as in cerebral mi

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Szabo, Peter M., George Lee, Scott Ely, et al. "CD8+ T cells in tumor parenchyma and stroma by image analysis (IA) and gene expression profiling (GEP): Potential biomarkers for immuno-oncology (I-O) therapy." Journal of Clinical Oncology 37, no. 15_suppl (2019): 2594. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.2594.

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2594 Background: Distribution patterns of CD8+ T cells within the tumor microenvironment (TME) can be assessed by IA, which may reflect underlying tumor biology and serve as a potential biomarker to assess the utility of I-O therapy. These patterns are variable and may be classified as immune desert (minimal infiltrate), excluded (T cells confined to tumor stroma or to the invasive margin), or inflamed (T cells diffusely infiltrating tumor parenchyma and stroma). We hypothesized that association of a GEP signature with abundance of parenchymal and stromal T-cell infiltrates may identify biomar

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Littner, M. R., G. M. Kazmi, and F. D. Lott. "Distribution of cyclooxygenase products with cyclooxygenase inhibition in isolated dog lung." Journal of Applied Physiology 61, no. 3 (1986): 988–93. http://dx.doi.org/10.1152/jappl.1986.61.3.988.

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Arachidonic acid metabolism can lead to synthesis of cyclooxygenase products in the lung as indicated by measurement of such products in the perfusate of isolated lungs perfused with a salt solution. However, a reduction in levels of cyclooxygenase products in the perfusate may not accurately reflect the inhibition of levels of such products as measured in lung parenchyma. We infused sodium arachidonate into the pulmonary circulation of isolated dog lungs perfused with a salt solution and measured parenchymal, as well as perfusate, levels of 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha), p

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Suki, Béla, Dimitrije Stamenović, and Rolf Hubmayr. "Lung Parenchymal Mechanics." Comprehensive Physiology 1, no. 3 (2011): 1317–51. https://doi.org/10.1002/j.2040-4603.2011.tb00360.x.

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AbstractThe lung parenchyma comprises a large number of thin‐walled alveoli, forming an enormous surface area, which serves to maintain proper gas exchange. The alveoli are held open by the transpulmonary pressure, or prestress, which is balanced by tissues forces and alveolar surface film forces. Gas exchange efficiency is thus inextricably linked to three fundamental features of the lung: parenchymal architecture, prestress, and the mechanical properties of the parenchyma. The prestress is a key determinant of lung deformability that influences many phenomena including local ventilation, reg

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Cotsoglou, Christian, Federica Bruno, Laura Lomaglio, et al. "The plow technique: An alternative method for the transection of liver parenchyma." Il Giornale di Chirurgia - Journal of the Italian Association of Hospital Surgeons 42, no. 3 (2022): e09. http://dx.doi.org/10.1097/ia9.0000000000000012.

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Background: Over the past 30 years, improvements in both technical skills and surgical equipment have been made to guarantee safe and effective liver parenchymal transection. In the present study, we propose a transection method, called “The Plow Technique” based on monopolar spray electrocoagulation in open hepatobiliary surgery. Methods: We conducted histological analyses on a cadaveric human liver measuring the diameters of all vascular structures at increasing depths of liver parenchyma. Furthermore, we retrospectively analyzed the data of 60 consecutive patients who underwent major and mi

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Uchizawa, Takamitsu. "Minute changes of cerebral parenchymal non-contrast computed tomography attenuation reflect cerebral volume alterations of blood." Neuroradiology Journal 34, no. 4 (2021): 341–47. http://dx.doi.org/10.1177/1971400921998981.

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Aims Non-infarcted acute cerebral ischaemic areas appear hypo-attenuated on non-contrast narrow-window computed tomography images. We aimed to determine the mechanism underlying minute computed tomography hypo-attenuation and visualise these attenuation changes on non-contrast computed tomography images. Methods The cerebral parenchyma was defined by pixels with attenuation of 20–50 Hounsfield units. We calculated the mean cerebral parenchymal attenuation in non-contrast computed tomography images. We analysed the correlation of complete blood counts with corresponding mean cerebral parenchyma

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Sherstiuk, Sergiy O., Stanislav I. Panov, Tetiana I. Liadova, Oleksij I. Tsivenko, and Liudmila L. Sherstiuk. "THE MORPHOMETRIC PARAMETERS OF THE PARENCHYMAL AND STROMAL LIVER COMPONENTS OF HEALTHY NEWBORNS FROM HEALTHY MOTHERS WITH A PHYSIOLOGICAL COURSE OF PREGNANCY." Wiadomości Lekarskie 73, no. 9 (2020): 1895–99. http://dx.doi.org/10.36740/wlek202009201.

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The aim: To determine the morphometric parameters of the parenchymal and stromal liver components of healthy newborns. Material and methods: The morphometric investigation included 45 liver tissue biopsies of healthy newborns. All morphometric parameters of the parenchymal and stromal liver components were calculated using the Avtandilov microscopic morphometric grid. It was inserted into the microscope ocular tube with a total × 200 microscope magnification. The number of points that were found on the corresponding types of parenchymal and stromal liver components was calculated. In every cas

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BUTLER, James P., Masao NAKAMURA, Hidetada SASAKI, Takao SASAKI, and Tamotsu TAKISHIMA. "Poissons' ratio of lung parenchyma and parenchymal interaction with bronchi." Japanese Journal of Physiology 36, no. 1 (1986): 91–106. http://dx.doi.org/10.2170/jjphysiol.36.91.

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Bueche, Celine Z., Cheryl Hawkes, Cornelia Garz та ін. "Hypertension drives parenchymal β‐amyloid accumulation in the brain parenchyma". Annals of Clinical and Translational Neurology 1, № 2 (2014): 124–29. http://dx.doi.org/10.1002/acn3.27.

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Mangla, Vivek, Shailendra Lalwani, Siddharth Mehrotra, Naimish Mehta, and Samiran Nundy. "Liver parenchymal transection techniques." Bhutan Health Journal 2, no. 1 (2016): 30–36. http://dx.doi.org/10.47811/bhj.19.

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While liver surgery has become safer with improvements in peri-operative management, parenchymal resection is the part of the procedure which is associated with major loss of blood and damage to important structures if not performed carefully. The ideal technique for hepatic parenchymal transection should be quick, easy to perform, reduce intra-operative blood loss and transfusion requirement, reduce post-operative bile leakage, and cause minimal damage to the surrounding hepatic parenchyma-- preferably at the lowest cost possible. This paper is a review of commonly used techniques for liver p

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Vozgoment, O. V., E. A. Kostenko, A. G. Nadtochiy, E. P. Fisenko, and N. V. Zaitseva. "Current Ultrasonography Potential in the Diagnosis of Juvenile Recurrent Parotitis." Innovative Medicine of Kuban, no. 3 (August 17, 2023): 45–53. http://dx.doi.org/10.35401/2541-9897-2023-26-3-45-53.

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Objective: To determine the diagnostic significance of sonographic signs indicating the parotid glands’ condition in children with juvenile recurrent parotitis (JRP). Materials and methods: We examined 42 patients with JRP and 30 children aged 3-17 years from the control group. Both groups underwent B-mode and color Doppler ultrasonography of parotid glands to assess linear dimensions, contours, structures, echogenicity, pronouncement of the stromal component, parenchymal vascularization, and condition of intraglandular lymph nodes. The diagnostic significance of the sonographic signs was asse

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Rydenfelt, Kristina, Runar Strand-Amundsen, Rune Horneland, et al. "Microdialysis and CO2 sensors detect pancreatic ischemia in a porcine model." PLOS ONE 17, no. 2 (2022): e0262848. http://dx.doi.org/10.1371/journal.pone.0262848.

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Background Pancreatic transplantation is associated with a high rate of early postoperative graft thrombosis. If a thrombosis is detected in time, a potentially graft-saving intervention can be initiated. Current postoperative monitoring lacks tools for early detection of ischemia. The aim of this study was to investigate if microdialysis and tissue pCO2 sensors detect pancreatic ischemia and whether intraparenchymal and organ surface measurements are comparable. Methods In 8 anaesthetized pigs, pairs of lactate monitoring microdialysis catheters and tissue pCO2 sensors were simultaneously ins

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Gareeballah, Awadia, Moawia Bushra Gameraddin, Suliman Salih, and Jumaa Tamboul. "Sonographic assessment of kidneys and associated abdominal findings in patients with renal parenchymal diseases." International Journal of Research in Medical Sciences 5, no. 3 (2017): 1048. http://dx.doi.org/10.18203/2320-6012.ijrms20170660.

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Background: The renal parenchymal diseases were common pathological conditions that involved the renal parenchyma. They cause damage to interstitia and glomerula and result in renal failure if left undiagnosed and untreated. The objective of the study was to assess the kidneys in renal parenchymal diseases in Sudanese patients.Methods: This cross-sectional study involved two hundred and six patients confirmed with renal parenchymal diseases. All the patients were scanned using ultrasonography. The echogenicity, kidney size, surface and thickness of renal cortex were assessed and the related ab

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Petukhov, U. I., S. M. Yermashkevich, U. I. Dziarkach, M. U. Kuncevicz, and A. P. Kutsko. "Differential diagnosis of acute pneumonia with acute abscess and gangrene of the lung using angiopulmonography with a nitroglycerin test." Health and Ecology Issues 21, no. 3 (2024): 24–31. http://dx.doi.org/10.51523/2708-6011.2024-21-3-03.

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Objective. To present the possibilities of angiopulmonography with a nitroglycerin test in the differential diagnosis of acute pneumonia with acute abscess and gangrene of the lung.Material and methods. А pulmonary angiogram with a nitroglycerin test was performed in 51 patients with suppurative inflammations of the lungs and pleura in cases where it was difficult to interpret computed tomography data.Results. Acute gangrenous lung abscess was diagnosed in 27 (53%) patients (absence of the parenchymal phase of contrast, including after administration of nitrospray, of which in 4 cases it was d

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Gupta, Shivani, Smita Manchanda, and Vatsla Dadhwal. "Ovarian torsion: incremental role of contrast-enhanced ultrasound." BMJ Case Reports 15, no. 12 (2022): e251285. http://dx.doi.org/10.1136/bcr-2022-251285.

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We highlight the role of contrast-enhanced ultrasound (CEUS) as a supplementary modality to ultrasound (USG) examination in ovarian torsion in this case report. The reported patient had clinical history suspicious of ovarian torsion; however, USG and Doppler flow study findings were equivocal. CEUS was performed to solve the diagnostic dilemma and to know the status of ovarian parenchymal viability which revealed non-enhancement of the ovarian cyst wall and pedicle throughout the USG examination thus establishing the diagnosis of non-viable or infarcted ovarian parenchyma. The per operative an

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Ferronato, Mariko, Jessica Thunell, and Riyad Karmy-Jones. "Parenchymal Injuries." Current Respiratory Medicine Reviews 11, no. 1 (2015): 35–40. http://dx.doi.org/10.2174/1573398x11666150427220921.

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Stamenovic, D., and T. A. Wilson. "Parenchymal stability." Journal of Applied Physiology 73, no. 2 (1992): 596–602. http://dx.doi.org/10.1152/jappl.1992.73.2.596.

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Both continuum and micromechanical models have been used to describe the mechanics of lung parenchyma. Different authors, using different models, have come to different conclusions about parenchymal stability. We show that the continuum model, augmented by bounds on the elastic moduli obtained from recent micromechanical modeling, yields the same conclusions about stability that have been obtained from purely micromechanical modeling: if the lung were homogeneous, it would be stable; local atelectasis would not occur at positive transpulmonary pressure. However, the same analysis yields the pr

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Min, Zaw. "Parenchymal neurocysticercosis." Internal and Emergency Medicine 10, no. 1 (2014): 105–7. http://dx.doi.org/10.1007/s11739-014-1089-0.

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Ma, Baoshun, Barbara Breen, and Jason H. T. Bates. "Influence of parenchymal heterogeneity on airway-parenchymal interdependence." Respiratory Physiology & Neurobiology 188, no. 2 (2013): 94–101. http://dx.doi.org/10.1016/j.resp.2013.06.005.

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Naik, Suprava, Rajendra V. Phadke, Sanjeev Kumar Bhoi, Gaurav Chauhan, and Neetu Soni. "Perfusion MRI in Cerebral Venous and Sinus Thrombosis." Neurology India 72, no. 4 (2024): 791–96. http://dx.doi.org/10.4103/neurol-india.ni_485_20.

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Background and Purpose: Cerebral venous and sinus thrombosis (CVST) leads to perfusion abnormality in the brain. Our aim was to assess perfusion abnormalities in the center and periphery of the parenchymal lesion in CVST patients and correlate with the clinical outcome. Materials and Methods: Dynamic susceptibility contrast (DSC) perfusion imaging was performed in patients with CVST. Relative cerebral blood flow (rCBF), relative cerebral blood volume (rCBV), and mean transit time (MTT) values were obtained in the center and periphery of the parenchymal lesion. Results: A total of 30 consecutiv

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Suk-Ouichai, Chalairat, Jitao Wu, Wen Dong, et al. "Tumor contact surface area as a predictor of functional outcomes after partial nephrectomy." Journal of Clinical Oncology 36, no. 6_suppl (2018): 675. http://dx.doi.org/10.1200/jco.2018.36.6_suppl.675.

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675 Background: New baseline GFR is a major factor for cancer survivorship after renal cancer surgery. Parenchymal mass preservation is the predominant factor associated with functional outcomes after partial nephrectomy (PN). Contact surface area (CSA) between the tumor and parenchyma may impact parenchymal preservation and predict functional outcomes after PN. We evaluated CSA as a predictor of parenchymal mass and function preserved by PN. Methods: 419 patients managed with PN had necessary studies to evaluate preoperative and postoperative parenchymal mass and renal function within the ope

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Johns, Imogen. "Use of thoracic ultrasound to investigate respiratory disease." UK-Vet Equine 4, no. 4 (2020): 106–11. http://dx.doi.org/10.12968/ukve.2020.4.4.106.

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Ultrasound examination can be used to identify both pleural and parenchymal lesions of the adult or foal thorax. While perhaps most useful for the identification, quantification and characterisation of pleural fluid, abnormalities in the pulmonary parenchyma can be visualised as long as the lesion is peripheral enough to result in a lack of aeration of the normal visceral pleural surface. Ultrasound examination is indicated in the investigation of suspected respiratory disease in foals and horses. In animals with suspected intrathoracic disease, ultrasound can be used to identify pleural effus

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Johns, Imogen. "Use of thoracic ultrasound to investigate respiratory disease: an update." UK-Vet Equine 7, no. 5 (2023): 184–90. http://dx.doi.org/10.12968/ukve.2023.7.5.184.

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Ultrasonographic examination of the adult or foal thorax can be used to identify both pleural and parenchymal lesions. Whilst perhaps most useful for the identification, quantification and characterisation of pleural fluid, abnormalities within the pulmonary parenchyma can be visualised as long as the lesion is peripheral enough to result in a lack of aeration of the normal visceral pleural surface. Ultrasonographic examination is indicated in the investigation of suspected respiratory disease in foals and horses. In animals with suspected intrathoracic disease, ultrasound can be used to ident

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Engelke, Christoph, John Quarmby, Gaurang Ubhayakar, Robert Morgan, Keith Holmes, and Anna-Maria Belli. "Autologous Thrombin: A New Embolization Treatment for Traumatic Intrasplenic Pseudoaneurysm." Journal of Endovascular Therapy 9, no. 1 (2002): 29–35. http://dx.doi.org/10.1177/152660280200900106.

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Purpose: To report the use of autologous thrombin for transcatheter embolization of a traumatic parenchymal splenic pseudoaneurysm. Case Report: A 15-year-old boy presented with a splenic parenchymal laceration after blunt abdominal trauma. The patient was managed conservatively but developed an intrasplenic pseudoaneurysm (grade III AAST scale) with subcapsular contrast extravasation after 3 weeks. Autologous thrombin was isolated from the patient's blood and subsequently delivered to the lesion by transcatheter superselective injection into the aneurysm neck. The patient was asymptomatic aft

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Adler, Andy, Elizabeth A. Cowley, Jason H. T. Bates, and David H. Eidelman. "Airway-parenchymal interdependence after airway contraction in rat lung explants." Journal of Applied Physiology 85, no. 1 (1998): 231–37. http://dx.doi.org/10.1152/jappl.1998.85.1.231.

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The constriction of pulmonary airways is limited by the tethering effect exerted by parenchymal attachments. To characterize this tethering effect at the scale of intraparenchymal airways, we studied the pattern of parenchymal distortion due to bronchoconstriction in a rat lung explant system. First, we measured the elastic modulus under tension for 2% (wt/vol) agarose alone (37.6 ± 1.5 kPa) and for agarose-filled lung (5.7 ± 1.3 kPa). The latter is similar to the elastic modulus of air-filled lung at total lung capacity (4.5–6 kPa) (S. J. Lai-Fook, T. A. Wilson, R. E. Hyatt, and J. R. Rodarte

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Krisht, Abed al Hadi, Kévin Grapin, Romain Chauvot de Beauchene, et al. "SARS-CoV2 pneumonia patients admitted to the ICU: Analysis according to clinical and biological parameters and the extent of lung parenchymal lesions on chest CT scan, a monocentric observational study." PLOS ONE 19, no. 9 (2024): e0308014. http://dx.doi.org/10.1371/journal.pone.0308014.

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Background CT-scan and inflammatory and coagulation biomarkers could help in prognostication of COVID-19 in patients on ICU admission. Objective The objectives of this study were to measure the prognostic value of the extent of lung parenchymal lesions on computed tomography (CT) and of several coagulation and inflammatory biomarkers, and to explore the characteristics of the patients depending on the extent of lung parenchymal lesions. Design Retrospective monocentric observational study achieved on a dataset collected prospectively. Setting Medical ICU of the university hospital of Clermont-

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Brandsma, Corry-Anke, Wim Timens, Marnix R. Jonker, Bea Rutgers, Jacobien A. Noordhoek, and Dirkje S. Postma. "Differential effects of fluticasone on extracellular matrix production by airway and parenchymal fibroblasts in severe COPD." American Journal of Physiology-Lung Cellular and Molecular Physiology 305, no. 8 (2013): L582—L589. http://dx.doi.org/10.1152/ajplung.00152.2013.

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Chronic obstructive pulmonary disease (COPD) is characterized by abnormal repair in the lung resulting in airway obstruction associated with emphysema and peripheral airway fibrosis. Because the presence and degree of airways disease and emphysema varies between COPD patients, this may explain the heterogeneity in the response to treatment. It is currently unknown whether and to what extent inhaled steroids can affect the abnormal repair process in the airways and lung parenchyma in COPD. We investigated the effects of fluticasone on transforming growth factor (TGF)-β- and cigarette smoke-indu

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Schwartz, D. A., J. R. Galvin, C. S. Dayton, W. Stanford, J. A. Merchant, and G. W. Hunninghake. "Determinants of restrictive lung function in asbestos-induced pleural fibrosis." Journal of Applied Physiology 68, no. 5 (1990): 1932–37. http://dx.doi.org/10.1152/jappl.1990.68.5.1932.

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We evaluated whether restrictive lung function among asbestos-exposed individuals with pleural fibrosis was caused by radiographically inapparent parenchymal inflammation and/or parenchymal fibrosis. All 24 study participants were sheet metal workers who were nonsmokers with normal parenchyma on posteroanterior chest radiograph. These subjects had either normal pleura (n = 7), circumscribed plaques (n = 9), or diffuse pleural thickening (n = 8). After controlling for age, years in the trade, and pack-years of smoking, we found that sheet metal workers with diffuse pleural thickening had a lowe

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Lambert, Rodney K., and Peter D. Paré. "Lung parenchymal shear modulus, airway wall remodeling, and bronchial hyperresponsiveness." Journal of Applied Physiology 83, no. 1 (1997): 140–47. http://dx.doi.org/10.1152/jappl.1997.83.1.140.

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Lambert, Rodney K., and Peter D. Paré. Lung parenchymal shear modulus, airway wall remodeling, and bronchial hyperresponsiveness. J. Appl. Physiol.83(1): 140–147, 1997.—When airways narrow, either through the action of smooth muscle shortening or during forced expiration, the lung parenchyma is locally distorted and provides an increased peribronchial stress that resists the narrowing. Although this interdependence has been well studied, the quantitative significance of airway remodeling to interdependence has not been elucidated. We have used an improved computational model of the bronchial r

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Mukhametdinova, Landysh M., Munir G. Tukhbatullin, and Elena E. Fomina. "THE IMPORTANCE OF ULTRASOUND EXAMINATION OF RENAL ALLOGRAFT." Acta medica Eurasica, no. 2 (June 25, 2024): 27–33. http://dx.doi.org/10.47026/2413-4864-2024-2-27-33.

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Kidney transplantation is an effective method of treating patients with end-stage chronic renal failure, as it improves the quality of life and has advantages in patient survival compared with dialysis methods of substitutive renal therapy. To date, ultrasound examination (ultrasound) is the most common diagnostic method for assessing the morphological state of a kidney transplant. Shear wave ultrasound elastography serves as an additional method for assessing the stiffness of the renal allograft parenchyma and early diagnosis of its dysfunction. The aim of the study was to determine the corre

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Oh, Bryan C., Paul G. Pagnini, Michael Y. Wang, et al. "STEREOTACTIC RADIOSURGERY: ADJACENT TISSUE INJURY AND RESPONSE AFTERHIGH-DOSE SINGLE FRACTION RADIATION." Neurosurgery 60, no. 1 (2007): 31–45. http://dx.doi.org/10.1227/01.neu.0000249191.23162.d2.

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Abstract RADIOSURGERY IS NOW the preferred treatment modality for many intracranial disease processes. Although almost 50 years have passed since it was introduced as a tool to treat neurological disease, investigations into its effects on normal tissues of the central nervous system are still ongoing. The need for these continuing studies must be underscored. A fundamental understanding of the brain parenchymal response to radiosurgery would permit development of strategies that would enhance and potentiate the radiosurgical treatment effects on diseased tissue while mitigating injury to norm

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Umairi, Rashid AL, Khadija AL Adawi, Maryam AL Khoori, Ahmed AL Lawati, and Sachin Jose. "COVID-19-Associated Thrombotic Complication: Is It Pulmonary Embolism or In Situ Thrombosis?" Radiology Research and Practice 2023 (July 3, 2023): 1–4. http://dx.doi.org/10.1155/2023/3844069.

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Objectives. Acute pulmonary embolism is a protentional fatal complication of COVID-19. The aim of this study is to investigate whether pulmonary embolism is due to thrombus migration from the venous circulation to the pulmonary arteries or due to local thrombus formation secondary to local inflammation. This was determined by looking at the distribution of pulmonary embolism in relation to lung parenchymal changes in patients with COVID-19 pneumonia. Methods. Retrospectively, we identified pulmonary computed tomography angiography (CTPA) of patients admitted to the Royal Hospital between Novem

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Habashy, Karl J., Tim Synold, Ye Feng, et al. "DDEL-15. PHARMACOKINETIC ANALYSIS OF CARBOPLATIN AND FLUORESCEIN BRAIN PENETRATION AND PERMANENCE FOLLOWING ULTRASOUND-BASED BLOOD-BRAIN BARRIER OPENING ON GLIOBLASTOMA CLINICAL TRIAL." Neuro-Oncology 26, Supplement_8 (2024): viii124. http://dx.doi.org/10.1093/neuonc/noae165.0481.

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Abstract The blood-brain barrier (BBB) impedes the passage of most circulating drugs into the brain. Low-intensity pulsed ultrasound with microbubbles (LIPU/MB) transiently opens the BBB, improving drug delivery to the brain. The implication of this transient BBB opening on parenchymal drug permanence is unknown. We compared the parenchymal levels and permanence/retention of temozolomide, carboplatin, and fluorescein, and investigated in a clinical trial (NCT04528680) the effect of LIPU/MB on the permanence of carboplatin and fluorescein in the human brain. Four patients underwent intraoperati

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Nikolova, Sonja. "COMPUTED TOMOGRAPHY IMAGING PRESENTATION IN THORACIC HYDATID CYSTS." KNOWLEDGE - International Journal 54, no. 4 (2022): 611–17. http://dx.doi.org/10.35120/kij5404611n.

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Hydatid cysts are widespread zoonosis that originate from the larval embodiment of the Echinococcusand can be frequently found in the lung and liver parenchyma, in addition, they emerge in various atypical locationsin the thoracic cavity such as the mediastinum, its vascular compounds and the heart, the interlobar fissures, thepleural and pericardial space, as well as the structures of the chest wall and the diaphragm. Computed tomographyas one of the most utilized instruments of radiology imaging has a crucial role in the diagnosis of hydatid cysts,depiction of their exact size and location,

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TAŞTEMUR, Sedat, Samet ŞENEL, Esin ÖLÇÜCÜOĞLU, Yusuf KASAP, and Emre UZUN. "Effects of renal parenchymal volume and total renal volume on success in retrograde intrarenal surgery." Endouroloji Bulteni 14, no. 1 (2022): 7–16. http://dx.doi.org/10.54233/endouroloji.1011076.

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Objective: Renal parenchymal volume known as an indicator of the number of nephrons in the kidney. We predict that the increase in renal parenchyma volume will increase diuresis and facilitate the excretion of fragments after RIRS procedure. Therefore, increased renal parenchymal volume might be suggested as a factor affecting the success of RIRS procedure.Material and Methods: Out of 238 patients who underwent RIRS in our clinic, 104 patients who underwent primary RIRS due to single kidney stone and who underwent contrast-enhanced computed tomoghraphy were included in the study. The demograph

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Nagpal, Prashant, Amin Motahari, Sarah E. Gerard, et al. "Case Studies in Physiology: Temporal variations of the lung parenchyma and vasculature in asymptomatic COVID-19 pneumonia: a multispectral CT assessment." Journal of Applied Physiology 131, no. 2 (2021): 454–63. http://dx.doi.org/10.1152/japplphysiol.00147.2021.

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We characterized the temporal changes of lung parenchyma and microvascular pathophysiology from COVID-19 infection in an asymptomatic young, healthy nonsmoking male using dual-energy CT. Lung parenchymal mechanics and microvascular disease followed different clinical courses. Heterogeneous perfused blood volume improved on follow-up visits up to 90 days. However, post COVID-19 mechanical heterogeneity of the lung parenchyma increased after apparent improvements in vascular abnormalities, even with normal spirometric indices.

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Elsaid, Nada, Ahmed Saied, Krishna Joshi, Jessica Nelson, John Baumgart, and Demetrius Lopes. "2D Parametric Parenchymal Blood Flow as a Predictor of the Hemorrhagic Events after Endovascular Treatment of Acute Ischemic Stroke: A Single-Center Retrospective Study." Interventional Neurology 7, no. 6 (2018): 522–32. http://dx.doi.org/10.1159/000491762.

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Background and Purpose: Intracranial hemorrhage (ICH) is one of the major adverse events related to the endovascular management of acute ischemic stroke. It is important to evaluate the risk of ICH as it may result in clinical deterioration of the patients. Development of tools which can predict the risk of ICH after thrombectomy can reduce the procedure-related morbidity and mortality. 2D parenchymal blood flow could potentially act as an indicator for ICH. Methods: 2D parenchymal blood flow was used to evaluate pre- and postthrombectomy digital subtraction angiography series of patients with

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Ma, Baoshun, and Jason H. T. Bates. "Continuum vs. spring network models of airway-parenchymal interdependence." Journal of Applied Physiology 113, no. 1 (2012): 124–29. http://dx.doi.org/10.1152/japplphysiol.01578.2011.

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The outward tethering forces exerted by the lung parenchyma on the airways embedded within it are potent modulators of the ability of the airway smooth muscle to shorten. Much of our understanding of these tethering forces is based on treating the parenchyma as an elastic continuum; yet, on a small enough scale, the lung parenchyma in two dimensions would seem to be more appropriately described as a discrete spring network. We therefore compared how the forces and displacements in the parenchyma surrounding a contracting airway are predicted to differ depending on whether the parenchyma is mod

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Ryumshina, N. I., I. V. Zyubanova, A. E. Sukhareva, et al. "Associations between MRI signs of kidney parenchymal changes and biomarkers of renal dysfunction in resistant hypertension." Siberian Journal of Clinical and Experimental Medicine 37, no. 1 (2022): 57–66. http://dx.doi.org/10.29001/2073-8552-2022-37-1-57-66.

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Objective. Resistant hypertension (RHT) is often associated with kidney injury and chronic kidney disease, especially in diabetic patients. Early detection of renal changes contributes to avoiding severe cardiovascular complications, but imaging characteristics of renal dysfunction in RHT remain unclear. The aim of the present study was to determine the relationships between the renal parenchyma volumes and biomarkers reflecting kidney function in a cohort of patients with RHT.Material and Methods. The study comprised 34 patients with RHT meeting the inclusion criteria. Evaluation of renal fun

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Kulcsár, Zsolt, Paolo Machi, Maria Isabel Vargas, Karl Schaller, and Karl Olof Lovblad. "Single-hole, ruptured parenchymal arteriovenous fistula of the mesencephalon : Not known vascular malformation of the brain or a posthemorrhagic entity?" Ideggyógyászati szemle 74, no. 3-4 (2021): 126–28. http://dx.doi.org/10.18071/isz.74.0126.

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The subtypes of brain arteriovenous malformations, with direct, single-hole fistulas without co-existing nidus are not described as existing entities inside the brain parenchyma but on the pial surface. True parenchymal arteriovenous malformations present with nidal structure, even if they are small, whereas surface lesions may present a direct fistulous configuration. In this case of midbrain haemorrhage a direct arteriovenous fistula was detected at the level of the red nucleus between a paramedian midbrain perforator artery and a paramedian parenchymal vein, with pseudo-aneurysm formation a

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Stepanov, C. O., D. V. Sidorov, A. V. Butenko, et al. "Ultrasound study of the liver in patients with metastatic colorectal cancer while planning surgical treatment." Russian Journal of Oncology 16, no. 6 (2011): 46–49. http://dx.doi.org/10.17816/onco39912.

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The overview deals with methods for evaluating the functional state of the hepatic parenchyma in patients with colorectal cancer while planning surgical treatment for liver metastases. The intact hepatic parenchyma should be estimated to reduce the risk of postoperative complications and mortality. Noninvasive diagnostic techniques fail to provide an objective assessment. Only a morphological study of parenchymal biopsy specimens will help rule out hepatic steatosis/ fibrosis and give surgeons information on the postresection liver remnant.

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Julia-Serda, G., N. A. Molfino, K. R. Chapman, et al. "Heterogeneous airway tone in asthmatic subjects." Journal of Applied Physiology 73, no. 6 (1992): 2328–32. http://dx.doi.org/10.1152/jappl.1992.73.6.2328.

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We examined the effect of volume history on the dynamic relationship between airways and lung parenchyma (relative hysteresis) in 20 asthmatic subjects. The acoustic reflection technique was employed to evaluate changes in airway cross-sectional areas during a slow continuous expiration from total lung capacity to residual volume and inspiration back to total lung capacity. Lung volume was measured continuously during this quasi-static maneuver. We studied three anatomic airway segments: extra- and intrathoracic tracheal and main bronchial segments. Plots of airway area vs. lung volume were ob

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Kurita, Yusuke, Daisuke Utsunomiya, Kensuke Kubota, et al. "Diagnostic Value of Contrast-Enhanced Dual-Energy Computed Tomography in the Pancreatic Parenchymal and Delayed Phases for Pancreatic Cancer." Tomography 10, no. 10 (2024): 1591–604. http://dx.doi.org/10.3390/tomography10100117.

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Background/Objectives: The usefulness of dual-energy computed tomography (DECT) for low absorption in the parenchymal phase and contrast effects in the delayed phase for pancreatic cancer is not clear. Therefore, the diagnostic capability of low-KeV images obtained using DECT for pancreatic cancer in the pancreatic parenchymal and delayed phases was evaluated quantitatively and qualitatively. Methods: Twenty-five patients with pancreatic cancer who underwent contrast-enhanced DECT were included. A total of 50 and 70 KeV CT images, classified as low-keV and conventional CT-equivalent images, we

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