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Dissertations / Theses on the topic 'Patched Gene'

Author: Grafiati

Published: 4 June 2021

Last updated: 20 February 2023

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Consult the top 19 dissertations / theses for your research on the topic 'Patched Gene.'

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1

Rahnama, Fahimeh. "Molecular complexities of patched signaling in cancer development /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-897-1/.

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2

Hidalgo-Downing, Alicia. "Molecular cloning of patched and analysis of its role in intrasegmental patterning in D. melanogaster." Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.258158.

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3

Undén, Anne Birgitte. "Studies on basal cell carcinoma with emphasis on the role of the human homologue of the drosophila patched gene /." Stockholm, 1997. http://diss.kib.ki.se/1997/91-628-2788-X.

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4

de, Zwaan Sally Elizabeth. "The Genetics of Basal Cell Carcinoma of the Skin." Thesis, The University of Sydney, 2008. http://hdl.handle.net/2123/3878.

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BCC is the commonest cancer in European-derived populations and Australia has the highest recorded incidence in the world, creating enormous individual and societal cost in management of this disease. The incidence of this cancer has been increasing internationally, with evidence of a 1 to 2% rise in incidence in Australia per year over the last two decades. The main four epidemiological risk factors for the development of BCC are ultraviolet radiation (UVR) exposure, increasing age, male sex, and inability to tan. The pattern and timing of UVR exposure is important to BCC risk, with childhood

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5

de, Zwaan Sally Elizabeth. "The Genetics of Basal Cell Carcinoma of the Skin." University of Sydney, 2008. http://hdl.handle.net/2123/3878.

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Doctor of Philosophy(PhD)<br>BCC is the commonest cancer in European-derived populations and Australia has the highest recorded incidence in the world, creating enormous individual and societal cost in management of this disease. The incidence of this cancer has been increasing internationally, with evidence of a 1 to 2% rise in incidence in Australia per year over the last two decades. The main four epidemiological risk factors for the development of BCC are ultraviolet radiation (UVR) exposure, increasing age, male sex, and inability to tan. The pattern and timing of UVR exposure is importan

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6

Daniels, Graeme P. "Characterisation of the Musca domestica (Diptera) homologue of the Drosophila melanogaster segment polarity gene patched, and the cloning of a cDNA fragment, PD, from Acheta domesticus." Thesis, University of Edinburgh, 1998. http://hdl.handle.net/1842/13559.

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The <I>Drosophila</I> segment polarity gene, <I>patched (ptc), </I>encodes a transmembrane protein that is the receptor for the hedgehog intercellular signalling molecule. Mutations in the human <I>ptc</I> gene, have been shown to be responsible for Gorlin's syndrome and a predisposition to nevoid basal cell carcinomas. In this study, partial clones of <I>patched </I>homologues were isolated from the long germ band developing house fly, <I>Musca domestica </I>(Diptera), and the intermediate germ band developing house cricket, <I>Acheta domesticus </I>(Orthoptera). Sequence data obtained from t

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7

Diniz, Marina Goncalves. "Estudo das múltiplas isoformas do gene Patched1 em ceratocisto odontogênico." Universidade Federal de Minas Gerais, 2008. http://hdl.handle.net/1843/BUOS-9TDFHF.

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O ceratocisto odontogênico (CO) é uma neoplasia benigna que possui um comportamento biológico agressivo. O CO está associado a alterações no gene homologo 1 ao gene patched de Drosophila (PTCH1). Este gene possui diversas isoformas geradas pelo uso alternativo do primeiro exon (1b, 1d e 1e). As isoformas podem possuir diferenças na sua expressão, na capacidade de agir como receptor da proteína sinalizadora Hedgehog (Hh) e na inibição da própria via. Levando em consideração que a via Hh pode estar envolvida na patogênese do CO, o objetivo deste estudo foi avaliar a presença dos diferentes RNAm

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8

Poon, Hiu-ching. "A study of the regulatory roles of Hedgehog in the enteric nervous system development by the conditional knockout of Patched1 enteric gene in the enteric neural crest cells." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42841604.

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9

Cordeiro, Erick M. G. "Patterns of infestation, dispersion, and gene flow in Rhyzopertha dominica based on population genetics and ecological modeling." Diss., Kansas State University, 2016. http://hdl.handle.net/2097/32642.

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Doctor of Philosophy<br>Department of Entomology<br>James F. Campbell<br>Thomas W. Phillips<br>Movement is a fundamental feature of animals that impacts processes across multiple scales in space and time. Due to the heterogeneous and fragmented nature of habitats that make up landscapes, movement is not expected to be random in all instances, and an increase in fitness is an expected consequence for those that can optimize movement to find valuable and scarce recourses. I studied the movement of Rhyzopertha dominica (Coleoptera: Bostrichidae), one of the most important pests of stored grain wo

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10

Liang, Guihua. "K⁺ channels in the inner ear : electrophysiological and molecular studies /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7349-971-4/.

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11

Guo, Man-Yuan. "Mechanisms involved in early Nod Factor signaling in legume root hairs : electrophysiological analyses in Medicago truncatula." Thesis, Montpellier, 2019. http://www.theses.fr/2019MONTG092.

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La symbiose entre les légumineuses et les rhizobia est d'une importance majeure dans les écosystèmes terrestres du fait de sa capacité à fixer l'azote atmosphérique. Le dialogue moléculaire entre les deux partenaires, qui mène finalement au développement de nodosités hébergeant les bactéries fixatrices, peut être initié par la liaison des facteurs Nod (NF) sécrétés par les rhizobia aux récepteurs à NF de la membrane plasmatique (PM) des poils racinaires de la légumineuse. Cela déclenche un influx de Ca2+ dans la cellule, suivi d'une cascade d'événements de signalisation ionique, impliquant des

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12

Alvarado, Livacic Cristóbal [Verfasser]. "Characterization of the role of RITA and KDM5A as RBP-J-kappa interacting proteins involved in the transcriptional control of Notch target genes, and characterization of the role of patched1 conditional deletion in mouse exocrine pancreas development / Cristóbal Alvarado Livacic." Ulm : Universität Ulm. Medizinische Fakultät, 2012. http://d-nb.info/1020449381/34.

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13

Klement, Göran. "Role of potassium channels in regulating neuronal activity /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-315-3/.

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14

Chai, Shin Luen Chai. "Novel Genetic Modifiers in a Monogenic Cardiac Arrhythmia." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1516618028568975.

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15

Nitzki, Frauke. "Patched-assoziierte Tumoren: Modifikatorgene und Pathogenese." Doctoral thesis, 2008. http://hdl.handle.net/11858/00-1735-0000-000D-F23C-8.

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16

Paus, Teresa Christina [Verfasser]. "Mutations- und Expressionsanalyse des Patched 2 (PTCH2)- Gens in meningealen und glialen Tumoren / vorgelegt von Teresa Christina Paus." 2007. http://d-nb.info/984780823/34.

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17

"Molecular and functional characterization of a novel G-patch containing protein-IER3IP1." 2003. http://library.cuhk.edu.hk/record=b6073729.

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Yiu Wai Han.<br>"June 2003."<br>Thesis (Ph.D.)--Chinese University of Hong Kong, 2003.<br>Includes bibliographical references (p. 146-156)<br>Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web.<br>Mode of access: World Wide Web.<br>Abstracts in English and Chinese.

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18

Wang, Xin-geng. "Patch exploitation by the parasitoids of Plutella xylostella (L.): from individual behaviour to population dynamics / Xin-geng Wang." Thesis, 2001. http://hdl.handle.net/2440/21743.

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Includes bibliographical references (leaves 204-230).<br>xvi, 230 leaves : ill. ; 30 cm.<br>Investigates the behaviour and ecology of the two major larval parasitoids of the diamondback moth, Plutella xylostella; Cotesia plutellae and Diadegma semiclausum.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Applied and Molecular Ecology, 2001

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19

Corrêa, Sonia A. L., C. J. Hunter, O. Palygin, S. C. Wauters, K. J. Martin, C. McKenzie, K. McKelvey, et al. "MSK1 regulates homeostatic and experience-dependent synaptic plasticity." 2012. http://hdl.handle.net/10454/5942.

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No<br>The ability of neurons to modulate synaptic strength underpins synaptic plasticity, learning and memory, and adaptation to sensory experience. Despite the importance of synaptic adaptation in directing, reinforcing, and revising the behavioral response to environmental influences, the cellular and molecular mechanisms underlying synaptic adaptation are far from clear. Brain-derived neurotrophic factor (BDNF) is a prime initiator of structural and functional synaptic adaptation. However, the signaling cascade activated by BDNF to initiate these adaptive changes has not been elucidated. We

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