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Journal articles on the topic 'Path signatures'

Author: Grafiati

Published: 21 December 2024

Last updated: 31 July 2025

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1

Kalsi, Jasdeep, Terry Lyons, and Imanol Perez Arribas. "Optimal Execution with Rough Path Signatures." SIAM Journal on Financial Mathematics 11, no. 2 (2020): 470–93. http://dx.doi.org/10.1137/19m1259778.

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2

Cartea, Álvaro, Imanol Pérez Arribas, and Leandro Sánchez-Betancourt. "Double-Execution Strategies Using Path Signatures." SIAM Journal on Financial Mathematics 13, no. 4 (2022): 1379–417. http://dx.doi.org/10.1137/21m1456467.

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3

Boland, Philip J. "Signatures of indirect majority systems." Journal of Applied Probability 38, no. 2 (2001): 597–603. http://dx.doi.org/10.1239/jap/996986765.

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If τ is the lifetime of a coherent system, then the signature of the system is the vector of probabilities that the lifetime coincides with the ith order statistic of the component lifetimes. The signature can be useful in comparing different systems. In this treatment we give a characterization of the signature of a system with independent identically distributed components in terms of the number of path sets in the system as well as in terms of the number of what we call ordered cut sets. We consider, in particular, the signatures of indirect majority systems and compare them with the signat

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Boland, Philip J. "Signatures of indirect majority systems." Journal of Applied Probability 38, no. 02 (2001): 597–603. http://dx.doi.org/10.1017/s0021900200020064.

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If τ is the lifetime of a coherent system, then the signature of the system is the vector of probabilities that the lifetime coincides with the ith order statistic of the component lifetimes. The signature can be useful in comparing different systems. In this treatment we give a characterization of the signature of a system with independent identically distributed components in terms of the number of path sets in the system as well as in terms of the number of what we call ordered cut sets. We consider, in particular, the signatures of indirect majority systems and compare them with the signat

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5

Mashchenko, Kirill Alekseevich. "Signature Methods for Time Series Analysis." Russian Digital Libraries Journal 28, no. 3 (2025): 681–700. https://doi.org/10.26907/1562-5419-2025-28-3-681-700.

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Signature methods are a powerful tool for time series analysis, transforming them into a form suitable for machine learning tasks. The article examines the fundamental concepts of path signatures, their properties, and geometric interpretation, as well as computational methods for various types of time series. Examples of signature method applications in different fields, including finance, medicine, and education, are presented, highlighting their advantages over traditional approaches. Special attention is given to synthetic data generation based on signatures, which is particularly relevant

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Fang, Yuan, Zhe Su, Jing Xie, et al. "Genomic signatures of pancreatic adenosquamous carcinoma (PASC)." Journal of Pathology 243, no. 2 (2017): 155–59. http://dx.doi.org/10.1002/path.4943.

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7

Jiang, Yunjiang, and Weijun Xu. "On the Number of Turns in Reduced Random Lattice Paths." Journal of Applied Probability 50, no. 2 (2013): 499–515. http://dx.doi.org/10.1239/jap/1371648957.

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We consider the tree-reduced path of a symmetric random walk on ℤd. It is interesting to ask about the number of turns Tn in the reduced path after n steps. This question arises from inverting the signatures of lattice paths: Tn gives an upper bound of the number of terms in the signature needed to reconstruct a ‘random’ lattice path with n steps. We show that, when n is large, the mean and variance of Tn in the asymptotic expansion have the same order as n, while the lower-order terms are O(1). We also obtain limit theorems for Tn, including the large deviations principle, central limit theor

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Jiang, Yunjiang, and Weijun Xu. "On the Number of Turns in Reduced Random Lattice Paths." Journal of Applied Probability 50, no. 02 (2013): 499–515. http://dx.doi.org/10.1017/s0021900200013528.

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We consider the tree-reduced path of a symmetric random walk on ℤ d . It is interesting to ask about the number of turns T n in the reduced path after n steps. This question arises from inverting the signatures of lattice paths: T n gives an upper bound of the number of terms in the signature needed to reconstruct a ‘random’ lattice path with n steps. We show that, when n is large, the mean and variance of T n in the asymptotic expansion have the same order as n, while the lower-order terms are O(1). We also obtain limit theorems for T n, including the large deviations principle, central limit

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Shestakova, Tatyana. "On A. D. Sakharov’s Hypothesis of Cosmological Transitions with Changes in the Signature of the Metric." Universe 7, no. 5 (2021): 151. http://dx.doi.org/10.3390/universe7050151.

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The paper discusses possible consequences of A. D. Sakharov’s hypothesis of cosmological transitions with changes in the signature of the metric, based on the path integral approach. This hypothesis raises a number of mathematical and philosophical questions. Mathematical questions concern the definition of the path integral to include integration over spacetime regions with different signatures of the metric. One possible way to describe the changes in the signature is to admit time and space coordinates to be purely imaginary. It may look like a generalization of what we have in the case of

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Blaudeau, Clément, Didier Rémy, and Gabriel Radanne. "Avoiding Signature Avoidance in ML Modules with Zippers." Proceedings of the ACM on Programming Languages 9, POPL (2025): 1962–91. https://doi.org/10.1145/3704902.

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We present ZipML, a new path-based type system for a fully fledged ML-module language that avoids the signature avoidance problem. This is achieved by introducing floating fields, which act as additional fields of a signature, invisible to the user but still accessible to the typechecker. In practice, they are handled as zippers on signatures, and can be seen as a lightweight extension of existing signatures. Floating fields allow to delay the resolution of instances of the signature avoidance problem as long as possible or desired. Since they do not exist at runtime, they can be simplified al

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Webster, Jonathan A., Andrew H. Beck, Mimansa Sharma, et al. "Variations in stromal signatures in breast and colorectal cancer metastases." Journal of Pathology 222, no. 2 (2010): 158–65. http://dx.doi.org/10.1002/path.2738.

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12

Kumar, Pankaj, Saurabh Kumar Sharma, and Kaveri Umesh Kadam. "Prolong the lifetime of sensor monitoring system using schedule matrix while employing digital signatures." Journal of Information and Optimization Sciences 44, no. 7 (2023): 1327–46. http://dx.doi.org/10.47974/jios-1286.

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In this paper a linear programing approach has been implemented for finding the energy efficient path for prolonging the network lifetime of sensor monitoring systems. For a given set of sensors and spots, a sensor can only monitor a single spot at a time and a spot can be the monitoring range of k-sensors. While using digital signatures on sensor nodes, a linear programming framework is designed to determine the system’s maximum life time. Digital signatures provide node authentication and non-repudiation service in wireless sensor network. Non-repudiation is supported by different types of d

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Volwerk, M., M. Delva, Y. Futaana, et al. "Corrigendum to "Substorm activity in Venus's magnetotail" published in Ann. Geophys., 27, 2321–2330, doi:10.5194/angeo-27-2321-2009, 2009." Annales Geophysicae 28, no. 10 (2010): 1877–78. http://dx.doi.org/10.5194/angeo-28-1877-2010.

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Abstract. A re-evaluation of the reconnection event reported by Volwerk et al. (2009) shows that the original interpretation of the magnetic field data as quadrupolar Hall-current signatures around a reconnection site was mistaken. It could be interpreted as the signature of reconnection in the presence of a guide field. The path of VEX through the active region in Venus's magnetotail is re-evaluated and the strongly energized ions associated to this event are now in agreement with the magnetic field data.

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14

Le Donne, Enrico, and Roger Züst. "Space of signatures as inverse limits of Carnot groups." ESAIM: Control, Optimisation and Calculus of Variations 27 (2021): 37. http://dx.doi.org/10.1051/cocv/2021040.

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We formalize the notion of limit of an inverse system of metric spaces with 1-Lipschitz projections having unbounded fibers. The construction is applied to the sequence of free Carnot groups of fixed rank n and increasing step. In this case, the limit space is in correspondence with the space of signatures of rectifiable paths in ℝn, as introduced by Chen. Hambly-Lyons’s result on the uniqueness of signature implies that this space is a geodesic metric tree. As a particular consequence we deduce that every path in ℝn can be approximated by projections of some geodesics in some Carnot group of

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Ban, Mohammed Khammas, Ismail Ismahani, and N. Marsono M. "Pre-filters in-transit malware packets detection in the network." TELKOMNIKA Telecommunication, Computing, Electronics and Control 17, no. 4 (2019): 1706–14. https://doi.org/10.12928/TELKOMNIKA.v17i4.12065.

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Conventional malware detection systems cannot detect most of the new malware in the network without the availability of their signatures. In order to solve this problem, this paper proposes a technique to detect both metamorphic (mutated malware) and general (non-mutated) malware in the network using a combination of known malware sub-signature and machine learning classification. This network-based malware detection is achieved through a middle path for efficient processing of non-malware packets. The proposed technique has been tested and verified using multiple data sets (metamorphic malwar

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Mamatjan, Yasin, Mathew Voisin, Farshad Nassiri, et al. "PATH-41. INTEGRATED MOLECULAR ANALYSIS REVEALS HYPERMETHYLATION AND OVEREXPRESSION OF HOX GENES TO BE POOR PROGNOSTICATORS IN IDH MUTANT GLIOMA." Neuro-Oncology 25, Supplement_5 (2023): v177. http://dx.doi.org/10.1093/neuonc/noad179.0671.

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Abstract BACKGROUND Diffuse gliomas represent over 80% of malignant brain tumors ranging from low-grade to aggressive high-grade lesions. Within IDH-mutant gliomas there is a high variability in survival and a need to more accurately predict outcome. METHODS To identify and characterize a predictive signature of outcome in gliomas, we utilized an integrative molecular analysis (using methylation, mRNA, copy number variation (CNV) and mutation data), analyzing a total of 729 IDH-mutant samples including a test set of 99 from University Health Network (UHN) and two validation cohorts including t

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Moore, P. J., T. J. Lyons, and J. Gallacher. "Using path signatures to predict a diagnosis of Alzheimer’s disease." PLOS ONE 14, no. 9 (2019): e0222212. http://dx.doi.org/10.1371/journal.pone.0222212.

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18

Brünig, Florian N., Manuel Rammler, Ellen M. Adams, Martina Havenith, and Roland R. Netz. "Spectral signatures of excess-proton waiting and transfer-path dynamics." Biophysical Journal 122, no. 3 (2023): 282a. http://dx.doi.org/10.1016/j.bpj.2022.11.1603.

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19

Herfs, Michael, Rémi Longuespée, Charles M. Quick, et al. "Proteomic signatures reveal a dualistic and clinically relevant classification of anal canal carcinoma." Journal of Pathology 241, no. 4 (2017): 522–33. http://dx.doi.org/10.1002/path.4858.

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He, Shuning, SF Gabby Krens, Huiqing Zhan та ін. "A ΔRaf1-ER-inducible oncogenic zebrafish liver cell model identifies hepatocellular carcinoma signatures". Journal of Pathology 225, № 1 (2011): 19–28. http://dx.doi.org/10.1002/path.2936.

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21

Roy, Vijaylaxmi, Devraj Lath, Vijay Sreegiriraju, et al. "PATH-36. DO GENE EXPRESSION PROFILES BETTER PREDICT OLIGODENDROGLIOMA SURVIVAL?" Neuro-Oncology 26, Supplement_8 (2024): viii186—viii187. http://dx.doi.org/10.1093/neuonc/noae165.0735.

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Abstract The WHO 2021 classification of oligodendroglioma grade 2 (G2) and grade 3 (G3), is separated by histopathology alone and does not universally reflect survival outcome. DNA methylation-based profiling also fails to separate oligodendroglioma grades. Our aim was to define transcriptome-based molecular subgroups that predict survival of oligodendroglioma (IDH-mutant and 1p/19q-codeleted) patients. Clinical and whole-transcriptome data for oligodendroglioma were obtained from TCGA (n=132), CGGA (n=53), and the Exsegen Genomics Research Biobank (n=16) (CTRI/2021/09/036861); while that of c

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22

Shen, Hao, and David S. Lazzara. "A space marching method for sonic boom near field predictions." International Journal of Aeroacoustics 23, no. 3-4 (2024): 420–35. http://dx.doi.org/10.1177/1475472x241230651.

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The conventional sonic boom propagation prediction method widely adopted in supersonic aircraft design involves a two-step procedure. In the first step, a compressible viscous or inviscid Computational Fluid Dynamics analysis is applied to the aircraft geometry at flight conditions to produce a flow field solution near the aircraft. Then in the second step, a one dimensional nonlinear Burgers’ equation model is used to propagate sonic boom signature traces from the near field solution at flight altitude to the ground along a ray path. For an accurate ground signature prediction the near field

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23

Clement, Blaudeau, Didier Rémy, and Gabriel Radanne. "Fulfilling OCaml Modules with Transparency." Proceedings of the ACM on Programming Languages 8, OOPSLA1 (2024): 194–222. http://dx.doi.org/10.1145/3649818.

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ML modules come as an additional layer on top of a core language to offer large-scale notions of composition and abstraction. They largely contributed to the success of OCaml and SML. While modules are easy to write for common cases, their advanced use may become tricky. Additionally, despite a long line of works, their meta-theory remains difficult to comprehend, with involved soundness proofs. In fact, the module layer of OCaml does not currently have a formal specification and its implementation has some surprising behaviors. Building on previous translations from ML modules to Fω, we propo

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24

Morley, S. K., and M. Lockwood. "The dependence of cusp ion signatures on the reconnection rate." Annales Geophysicae 21, no. 4 (2003): 947–53. http://dx.doi.org/10.5194/angeo-21-947-2003.

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Abstract. The interpretation of structure in cusp ion dispersions is important for helping to understand the temporal and spatial structure of magnetopause reconnection. "Stepped" and "sawtooth" signatures have been shown to be caused by temporal variations in the reconnection rate under the same physical conditions for different satellite trajectories. The present paper shows that even for a single satellite path, a change in the amplitude of any reconnection pulses can alter the observed signature and even turn sawtooth into stepped forms and vice versa. On 20 August 1998, the Defense Meteor

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25

Teuhola, J. "Path signatures: a way to speed up recursion in relational databases." IEEE Transactions on Knowledge and Data Engineering 8, no. 3 (1996): 446–54. http://dx.doi.org/10.1109/69.506711.

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26

Hernández-García, C., J. San Román, L. Plaja, and A. Picón. "Quantum-path signatures in attosecond helical beams driven by optical vortices." New Journal of Physics 17, no. 9 (2015): 093029. http://dx.doi.org/10.1088/1367-2630/17/9/093029.

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27

Chaudhari, Shilpa, R. Aparna, and Archana Rane. "A Survey on Proxy Re-Signature Schemes for Translating One Type of Signature to Another." Cybernetics and Information Technologies 21, no. 3 (2021): 24–49. http://dx.doi.org/10.2478/cait-2021-0028.

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Abstract Proxy Re-Signature (PRS) complements well-established digital signature service. Blaze-Bleumer-Strauss discussed PRS in 1998 for translating a signature on a message from Alice into a signature from Bob on the same message at semi-trusted proxy which does not learn any signing-key and cannot produce new valid signature on new message for Alice or Bob. PRS has been largely ignored since then but it has spurred considerable research interest recently for sharing web-certificates, forming weak-group signatures, and authenticating network path. This article provides a survey summarizing a

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Seeger, Stefan, and Markus Weiler. "Temporal dynamics of tree xylem water isotopes: in situ monitoring and modeling." Biogeosciences 18, no. 15 (2021): 4603–27. http://dx.doi.org/10.5194/bg-18-4603-2021.

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Abstract. We developed a setup for a fully automated, high-frequency in situ monitoring system of the stable water isotope deuterium and 18O in soil water and tree xylem. The setup was tested for 12 weeks within an isotopic labeling experiment during a large artificial sprinkling experiment including three mature European beech (Fagus sylvatica) trees. Our setup allowed for one measurement every 12–20 min, enabling us to obtain about seven measurements per day for each of our 15 in situ probes in the soil and tree xylem. While the labeling induced an abrupt step pulse in the soil water isotopi

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MESSINGER, DAVID W., CARL SALVAGGIO, and NATALIE M. SINISGALLI. "DETECTION OF GASEOUS EFFLUENTS FROM AIRBORNE LWIR HYPERSPECTRAL IMAGERY USING PHYSICS-BASED SIGNATURES." International Journal of High Speed Electronics and Systems 17, no. 04 (2007): 801–12. http://dx.doi.org/10.1142/s0129156407004990.

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Detection of gaseous effluent plumes from airborne platforms provides a unique challenge to the remote sensing community. The measured signatures are a complicated combination of phenomenology including effects of the atmosphere, spectral characteristics of the background material under the plume, temperature contrast between the gas and the surface, and the concentration of the gas. All of these quantities vary spatially further complicating the detection problem. In complex scenes simple estimation of a “residual” spectrum may not be possible due to the variability in the scene background. A

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Ning, Gang, Jonathan G. Bijron, Yusuke Yamamoto, et al. "The PAX2-null immunophenotype defines multiple lineages with common expression signatures in benign and neoplastic oviductal epithelium." Journal of Pathology 234, no. 4 (2014): 478–87. http://dx.doi.org/10.1002/path.4417.

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Hassan, Abdullah Mohammed, and Zahir Al-Khafaji. "Determining reliability signature by minimal cut method for complex-parallel network." Journal of Discrete Mathematical Sciences and Cryptography 27, no. 5 (2024): 1627–32. http://dx.doi.org/10.47974/jdmsc-2005.

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The process of counting minimal cut sets (MCS) in a network is typically more difficult than finding minimal path sets (MPS). The first aim of this work is to provide a precise and effective method for counting the (MCS) of directed networks. The second aim is to calculate the effectiveness of a complex-parallel network using the (MCM) to evaluate the reliability of a complex-parallel network. The (MCM) has been applied for predicting network reliability, minimal (MS), tails signatures (TS), signatures, and Barlow-Brochan indexes.

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Capozziello, Salvatore, Richard Pinčák, and Erik Bartoš. "A Supersymmetry and Quantum Cryptosystem with Path Integral Approach in Biology." Symmetry 12, no. 8 (2020): 1214. http://dx.doi.org/10.3390/sym12081214.

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The source of cancerous mutations and the relationship to telomeres is explained in an alternative way. We define the smallest subunit in the genetic code as a loop braid group element. The loop braid group is suitable to be defined as a configuration space in the process of converting the information written in the DNA into the structure of a folded protein. This smallest subunit, or a flying ring in our definition, is a representation of 8-spinor field in the supermanifold of the genetic code. The image of spectral analysis from the tensor correlation of mutation genes as our biological syst

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Xian, Wa, Alexander Miron, Michael Roh, et al. "The LiâFraumeni syndrome (LFS): a model for the initiation of p53 signatures in the distal Fallopian tube." Journal of Pathology 220, no. 1 (2010): 17–23. http://dx.doi.org/10.1002/path.2624.

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Kersch, Cymon, Cheryl Claunch, Prakash Ambady, et al. "PATH-63. TRANSCRIPTIONAL SIGNATURES IN HISTOLOGIC STRUCTURES WITHIN GLIOBLASTOMA TUMORS MAY PREDICT PERSONALIZED TREATMENT SENSITIVITY AND SURVIVAL." Neuro-Oncology 21, Supplement_6 (2019): vi157. http://dx.doi.org/10.1093/neuonc/noz175.658.

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Abstract OBJECTIVE Personalized treatment strategies in Glioblastoma multiforme (GBM) has been hampered by intra-tumoral heterogeneity. The goals of this study were to (1) determine the impact of intra-tumoral heterogeneity on established predictive and prognostic transcriptional signatures in human GBM, and (2) develop methods to mitigate the impact of tissue heterogeneity on transcriptomic-based patient stratification. METHODS We analyzed transcriptional profiles of GBM histological structures from the open-source Ivy Glioblastoma Atlas Project. To generate these data, infiltrative tumor, le

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Pérez‐Mies, Belén, Irene Carretero‐Barrio, and José Palacios. "Immune‐related gene expression signatures: a step forward in the stratification of patients with ovarian clear cell carcinoma ^†." Journal of Pathology 256, no. 4 (2022): 366–68. http://dx.doi.org/10.1002/path.5850.

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Angulo, B., A. Suarez-Gauthier, F. Lopez-Rios, et al. "Expression signatures in lung cancer reveal a profile for EGFR-mutant tumours and identify selective PIK3CA overexpression by gene amplification." Journal of Pathology 214, no. 3 (2007): 347–56. http://dx.doi.org/10.1002/path.2267.

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Deutsch, AJA, A. Aigelsreiter, E. Steinbauer, et al. "Distinct signatures of B-cell homeostatic and activation-dependent chemokine receptors in the development and progression of extragastric MALT lymphomas." Journal of Pathology 215, no. 4 (2008): 431–44. http://dx.doi.org/10.1002/path.2372.

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Graham, Richard T., Blake E. Sells, Jessica Fleming, et al. "PATH-15. PROTEOMIC SIGNATURES PREDICT GRADE IN PEDIATRIC AND YOUNG ADULT INFILTRATIVE ASTROCYTOMAS." Neuro-Oncology 22, Supplement_3 (2020): iii427. http://dx.doi.org/10.1093/neuonc/noaa222.650.

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Abstract BACKGROUND Infiltrative astrocytomas in children and young adults pose a treatment challenge due to the difficulty of achieving gross total resection and tumor resistance to irradiation and chemotherapy. Histopathologic grade is an essential part of determining prognosis and treatment, but it is subjective and provides limited understanding of the molecular mechanisms underlying tumor development and progression. METHODS We performed liquid chromatography/mass spectrometry (LC/MS-MS) on 28 FFPE samples of primary infiltrative astrocytomas (10 grade II, 8 grade III and 10 grade IV – WH

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Lai, Xiaojia Zuo, Xintong Yang, et al. "PATH-03. FERROPTOSIS-RELATED LONG NON-CODING RNA SIGNATURES PREDICT PROGNOSIS IN PATIENTS WITH GLIOMA." Neuro-Oncology 23, Supplement_6 (2021): vi115. http://dx.doi.org/10.1093/neuonc/noab196.456.

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Abstract Ferroptosis, with iron-dependent and ROS-dependent, is a novel type of cell death in a variety of diseases and some studies confirmed that ferroptosis-related lncRNAs are involved in the occurrence and development of several cancers. However, the ferroptosis-related lncRNA in the role of gliomas is unclear. Here, we constructed a prognostic scoring model of ferroptosis-related lncRNAs in gliomas. Data were downloaded from the Chinese glioma genome atlas (CGGA), the cancer genome atlas, and FerrDb database. In this study, we found 1051 lncRNAs associated with ferroptosis by Spearman's

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Oettinger, Marcel, Lars Wein, Dajan Mimic, Philipp Gilge, Ulrich Hartmann, and Joerg Seume. "Automated detection of hot-gas path defects by Support Vector Machine based analysis of exhaust density fields." Journal of the Global Power and Propulsion Society, May (July 13, 2021): 1–16. http://dx.doi.org/10.33737/jgpps/137952.

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Defects in the hot-gas path of aero engines have been shown to leave typical signatures in the density distribution of the exhaust jet. These signatures are superposed when several defects are present. For improved maintenance and monitoring applications, it is important to not only detect that there are defects present but to also identify the individual classes of defects. This diagnostic approach benefits both, the analysis of prototype or acceptance test and the preparation of Maintenance, Repair, and Overhaul. Recent advances in the analysis of tomographic Background-Oriented Schlieren (B

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Holler, M., A. Zaïr, F. Schapper, et al. "Ionization effects on spectral signatures of quantum-path interference in high-harmonic generation." Optics Express 17, no. 7 (2009): 5716. http://dx.doi.org/10.1364/oe.17.005716.

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Power, Cameron E. N., and Aldona Wiacek. "On path length, beam divergence, and retroreflector array size in open-path FTIR spectroscopy." Atmospheric Measurement Techniques 18, no. 11 (2025): 2537–52. https://doi.org/10.5194/amt-18-2537-2025.

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Abstract. Open-path Fourier transform infrared (OP-FTIR) spectroscopy is an established technique used to measure boundary layer trace gas concentrations, consisting (in this work) of a spectrometer with an active mid-IR source coupled to a single transmitting and receiving telescope, as well as a cube-corner retroreflector array separated from the spectrometer and telescope by an atmospheric path. The detection limit at first increases with increasing optical path length (OPL) in the atmosphere, which controls target gas spectral absorption depth; however, open-path beam divergence can lead t

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Tang, Karen, David Kurland, Varshini Vasudevaraja, Jonathan Serrano, Alireza Radmanesh, and Matija Snuderl. "PATH-40. PROFILING PLEOMORPHIC XANTHROASTROCYTOMA WITH DNA METHYLATION AND EXPLORING THE TUMOR IMMUNE CELL-TYPE COMPOSITION WITH METHYLATION-BASED DECONVOLUTION." Neuro-Oncology 21, Supplement_6 (2019): vi152. http://dx.doi.org/10.1093/neuonc/noz175.636.

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Abstract INTRODUCTION Pleomorphic xanthoastrocytoma (PXA) is a rare type of brain tumor that commonly affects children and young adults. PXAs are typically characterized by tumor lymphocytic infiltration, but the significance of the tumor immune microenvironment has not yet been well-defined. In this study, we correlated DNA methylation profiling of PXAs with clinical outcome and explored the tumor microenvironment by analyzing inflammatory cell populations. METHODS We retrospectively analyzed 30 tumor samples, of which 21 tumor samples from 18 subjects had a diagnosis of PXA both by DNA methy

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Chen, Zhihua, Denis O’Meally, David Frankhouser, et al. "PATH-06. DNA METHYLATION PATTERNS AND IMMUNE MICROENVIRONMENT IN CYSTICGBM." Neuro-Oncology 23, Supplement_6 (2021): vi115—vi116. http://dx.doi.org/10.1093/neuonc/noab196.458.

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Abstract As a rare subtype of glioblastomas (GBM), genetic features in cystic GBM (cGBM) are still largely unknown. We have previously identified a series of active T cell subsets and positive cytokines/chemocytokines in the cystic fluid of cGBMs, including IFN-gamma, IL-2, IL-6, IL-8, TNF-alpha, and MIP-1alpha/beta. This study aimed to evaluate the prognosis of cGBM through DNA methylation patterns and immune microenvironment transcriptional signatures. IvyGAP, EGA and fresh samples from a prospective Chinese cohort were collected to investigate genomic signatures, immune microenvironment and

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Salim, Renisha Pulinchuvallil, and Rajesh Ramachandran. "Link stability - based optimal routing path for efficient data communication in MANET." International Journal of Advances in Intelligent Informatics 10, no. 3 (2024): 471. https://doi.org/10.26555/ijain.v10i3.1558.

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The paper delves into the complexities of Mobile Ad hoc Networks (MANETs), which consist of a diverse array of wireless nodes. In such networks, routing packets poses a significant challenge due to their dynamic nature. Despite the variety of techniques available for optimizing routing in MANETs, persistent issues like packet loss, routing overhead, and End-to-End Delay (EED) remain prevalent. In response to these challenges, the paper proposes a novel approach for efficient Data Communication (DC) by introducing a Link Stability (LS)-based optimal routing path. This approach leverages several

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Shih, Barbara B., Ajit J. Nirmal, Denis J. Headon, Arne N. Akbar, Neil A. Mabbott, and Tom C. Freeman. "Derivation of marker gene signatures from human skin and their use in the interpretation of the transcriptional changes associated with dermatological disorders." Journal of Pathology 241, no. 5 (2017): 600–613. http://dx.doi.org/10.1002/path.4864.

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Morfill, G. E., and M. J. Freyberg. "Energetic Particles in the Local Bubble." International Astronomical Union Colloquium 166 (1997): 177–86. http://dx.doi.org/10.1017/s0252921100070949.

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AbstractThe current status of observations of energetic particles in the “local bubble” is reviewed. This includes primarily “direct” measurements of cosmic rays made in the Solar System, but also the “remote sensing” made possible by observing cosmic ray produced γ-rays in the nearby interstellar clouds. Since the energetic events responsible for the formation of our local bubble may also have produced copious amounts of cosmic rays, fossil records are examined to determine whether there is a corresponding signature. The observations show that: 1) the cosmic ray (proton) intensity is fairly h

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Piscia, Roberta, Michela Mazzoni, Roberta Bettinetti, Rossana Caroni, Davide Cicala, and Marina Marcella Manca. "Stable Isotope Analysis and Persistent Organic Pollutants in Crustacean Zooplankton: The Role of Size and Seasonality." Water 11, no. 7 (2019): 1490. http://dx.doi.org/10.3390/w11071490.

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Zooplankton is crucial for the transfer of matter, energy, and pollutants through aquatic food webs. Primary and secondary consumers contribute to the abundance and standing stock biomass, which both vary seasonally. By means of taxa- and size-specific carbon and nitrogen stable isotope analysis, the path of pollutants through zooplankton is traced and seasonal changes are addressed, in an effort to understand pollutant dynamics in the pelagic food web. We analyzed zooplankton plurennial changes in concentration of polychlorinated biphenyls (PCBs) and dichlorodiphenyltrichloroethane and its re

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Haller, Florian, Anja von Heydebreck, Jitao David Zhang, et al. "Localization- and mutation-dependent microRNA (miRNA) expression signatures in gastrointestinal stromal tumours (GISTs), with a cluster of co-expressed miRNAs located at 14q32.31." Journal of Pathology 220, no. 1 (2009): 71–86. http://dx.doi.org/10.1002/path.2610.

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Rice, J. A., and S. M. Wu. "Acoustic Emission Source and Transmission Path Characterization Through Homomorphic Processing." Journal of Engineering for Industry 116, no. 1 (1994): 32–41. http://dx.doi.org/10.1115/1.2901807.

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Acoustic emission (AE) has been chosen as a means of monitoring cutting system changes from remote sensor locations. The determination of a processing strategy which can remove signal transmission path variability has been explored. This strategy, termed homomorphic processing, is developed and tested on both simulated and experimentally collected data. The recovery properties of this strategy are analyzed in terms of both AE source characterization and signal path transmission effects. These properties are found to be influenced by the choice of homomorphic lifter cutoff time. Guidelines are

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