Academic literature on the topic 'Pathogenesis'

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Journal articles on the topic "Pathogenesis"

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Tanashyan, M. M., K. V. Antonova, N. E. Spryshkov, A. А. Panina, O. V. Lagoda, and E. P. Shchukina. "Diabetic Polyneuropathy: from Pathogenesis to Pathogenetic Therapy." Effective Pharmacotherapy 20, no. 8 (2024): 54–62. http://dx.doi.org/10.33978/2307-3586-2024-20-8-54-62.

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The growing worldwide prevalence of prediabetes and diabetes mellitus (DM) has led to an increase in the incidence of related chronic complications, the most common of which is diabetic polyneuropathy (DPN). The development of DPN is caused by chronic hyperglycemia and potentially modifiable cardiovascular risk factors, including elevated triglyceride levels, body mass index, smoking and hypertension. Social determinants of health are also risk factors for DPN. The review presents data on the pathophysiology of DPN with consideration of the causes of the sequence of symptoms. Discussed the mec
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Orazov, M. R., V. E. Radzinsky, E. D. Dolgov, and Yu G. Abramashvili. "Pathogenesis and pathogenetic options in endometriosis management." Voprosy ginekologii, akušerstva i perinatologii 22, no. 1 (2023): 92–104. http://dx.doi.org/10.20953/1726-1678-2023-1-92-104.

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This article provides a literature review on the etiopathogenesis of endometriosis. Particular attention was paid to genetic and molecular biological aspects of endometriosis. The issues of conservative management of patients with confirmed endometriosis were also considered. The use of dienogest in the treatment of patients with endometriosis was substantiated. Key words: endometriosis, etiopathogenesis, genetic and molecular determinants, dienogest
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Strokov, I. A., and V. V. Oganov. "Pathogenesis, evaluation and pathogenetic therapy of diabetic polyneuropathy." Neurology, Neuropsychiatry, Psychosomatics 13, no. 3 (2021): 99–106. http://dx.doi.org/10.14412/2074-2711-2021-3-99-106.

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The increase in the number and life expectancy of patients with diabetes mellitus (DM) worldwide determines the high prevalence of late complications of diabetes, including diabetic polyneuropathy (DPN), the most common type of polyneuropathy. Oxidative stress is considered the main reason for the cellular pathology development in diabetes mellitus, which determines the use of antioxidants for the DPN treatment. Alpha-lipoic acid (ALA), a natural fat-soluble antioxidant, is the most effective drug for reducing DPN symptoms. Furthermore, the symptom-modifying effect of ALA has been shown in num
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Roy, Saumendu Deb. "Pathogenesis of COVID-19." INDIAN RESEARCH JOURNAL OF PHARMACY AND SCIENCE 7, no. 4 (2020): 2354–58. http://dx.doi.org/10.21276/irjps.2020.7.3.3.

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Galante, Iv. "A. Bakk & Gh. Tamasescu Ueber die Aetiologie und Pathogenese der Epilepsie und deren Therapie. Wiener Med. W. No. 17, 1933." Kazan medical journal 29, no. 5-6 (2022): 489. http://dx.doi.org/10.17816/kazmj89620.

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Bakk and Tamasescu (A. Bakk Gh. Tamasescu Ueber die Aetiologie und Pathogenese der Epilepsie und deren Therapie. Wiener Med. W. No. 17, 1933) give a good concise overview of the etiology, pathogenesis and treatment of epilepsy. Epilepsy is an organic syndrome with a different etiology and multiple pathogenetic factors, which explains that the methods of treatment for epilepsy vary enormously.
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Kim, Young Kyoon, and Younsuck Koh. "Pathogenesis." Tuberculosis and Respiratory Diseases 50, no. 5 (2001): 525. http://dx.doi.org/10.4046/trd.2001.50.5.525.

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Witz, Craig, and Robert Schenken. "Pathogenesis." Seminars in Reproductive Medicine 15, no. 03 (1997): 199–208. http://dx.doi.org/10.1055/s-2008-1068749.

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A, Abdelmoktader. "Mycobacterial Tuberculosis Epidemiology and Pathogenesis." Virology & Immunology Journal 4, no. 4 (2020): 1–7. http://dx.doi.org/10.23880/vij-16000259.

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Mycobacterium tuberculosis (MTB) is an acid fast bacterium (AFB); it has tough cell wall and circular chromosome. It is transmitted through the airborne route and cause tuberculosis (TB). The distribution of tuberculosis is not uniform across the globe; about 80% of the population in many Asian and African countries and it is the second most common cause of death from infectious disease after HIV. Organisms deposited mainly in the upper lung zones, kidneys and bones. In persons with intact cell-mediated immunity (CMI), collections of activated T cells and macrophages form granulomas that limit
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Gollnick, Harald P. M., Christos C. Zouboulis, Hirohiko Akamatsu, Ichiro Kurokawa, and Anja Schulte. "Pathogenesis and Pathogenesis Related Treatment of Acne." Journal of Dermatology 18, no. 9 (1991): 489–99. http://dx.doi.org/10.1111/j.1346-8138.1991.tb03122.x.

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HAYASHI, Koichi. "Pathogenesis of Hypertension -Kidney as a Pathogenetic Organ of Hypertension." Internal Medicine 40, no. 2 (2001): 153–56. http://dx.doi.org/10.2169/internalmedicine.40.153.

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Dissertations / Theses on the topic "Pathogenesis"

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Booler, Helen. "Pathogenetic mechanisms in the dystroglycanopathies pathogenesis." Thesis, Royal Veterinary College (University of London), 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.669190.

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Khamas, E. J. "Pathogenesis of staphylococcosis." Thesis, University of Nottingham, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234678.

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deLeeuw, Ronald John. "Mantle cell lymphoma pathogenesis." Thesis, University of British Columbia, 2009. http://hdl.handle.net/2429/12469.

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Mantle cell lymphoma (MCL) is an aggressive non-Hodgkin’s lymphoma with a median patient survival time of 3 years. Although the characteristic t(11;14)(q13;q32) is found in virtually all cases, experimental evidence suggests that this event alone is insufficient to result in lymphoma and secondary genomic alterations are required. Therefore, secondary genetic alterations have been proposed as essential in MCL pathogenesis. Within this thesis I describe the creation of a novel assay to determine segmental copy number alterations at a previously unprecedented resolution. This new assay necessita
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Sissons, James Robert. "Pathogenesis of Alanthamoeba encephalitis." Thesis, Birkbeck (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429097.

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Cowie, Danielle. "Iron and Tuberculosis pathogenesis." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/86566.

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Thesis (MSc)--Stellenbosch University, 2014.<br>ENGLISH ABSTRACT: Iron is an essential element that plays a role in the process of respiration, oxygen transport and as a principle cofactor to several enzymes. Iron homeostasis is a finely regulated process since excess levels become toxic to healthy cells via the production of reactive oxygen species. A plethora of genes that control several key points throughout this regulatory process have been identified. Research focusing on changes in expression levels and downstream functional effects of these genes has become increasingly important over
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Yau, Belinda. "Pathogenesis of pneumococcal meningitis." Thesis, The University of Sydney, 2014. http://hdl.handle.net/2123/12485.

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Streptococcus pneumoniae (SP) meningitis remains a significant cause of global childhood mortality, and a potential epidemic pathogen despite improving vaccinations schemes. Neuropathology in pneumococcal meningitis (PM) is attributed to both bacterial products and the host-mediated proinflammatory response. Proinflammatory cytokine interferon-gamma (IFNγ) is associated with macrophage activation and regulating MHC Class I expression in innate immunity. IFNγ gene knockout (GKO) mice inoculated with ~5 x 103 CFU of SP/mouse were significantly protected against fatal PM, compared to C57Bl/6 WT m
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Cartón, García Fernando. "Myosin VB in intestinal pathogenesis." Doctoral thesis, Universitat Autònoma de Barcelona, 2017. http://hdl.handle.net/10803/458251.

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Miosina VB es una proteína que actúa como un motor molecular usando la energía del ATP para moverse a lo largo de filamentos de actina. Participa en el trafico intracelular de endosomas de reciclaje en la parte subapical de células polarizadas y no polarizadas. Su expresión es muy abundante en el intestino donde participa en el establecimiento y mantenimiento de la polaridad de los enterocitos. Mutaciones en MYO5B causan la enfermedad de inclusión de microvellosidades, in raro trastorno congénito que afecta a las células epiteliales del intestino cursando con diarrea acuosa persistente que sue
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Hamoudi, Rifat A. "Molecular pathogenesis of MALT lymphoma." Thesis, University of Cambridge, 2010. https://www.repository.cam.ac.uk/handle/1810/238398.

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Mucosa associated lymphoid tissue (MALT) lymphoma is characterized by t(11;18)(q21;q21)/API2-MALT1, t(1;14)(p22;q32)/BCL10-IGH andt(14;18)(q32;q21)/IGH-MALT1, which commonly activate the NF-κB pathway. Gastric MALT lymphomas harbouring such translocation do not respond to Helicobacter pylori eradication, while those without translocation can be cured by antibiotics. To understand the molecular mechanism of MALT lymphoma with and without chromosome translocation, 24 cases (15 translocation-positive and 9 translocation-negative) of MALT lymphomas together with 7 follicular lymphomas and 7 mantle
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Alam, Sam Mohammad Kutubul. "Pathogenesis of Langerhans Cell Histiocytosis." Thesis, Imperial College London, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.487289.

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The Langerhans cell (LC) is a histiocytic cell that represents a resident immigrant population in the epidermis and functions as a professional antigen presenting cell (APC). Langerhans cell histiocytosis (LCH) is a rare disorder that can affect both adults and children and can involve various organs. Clinically the disease ranges from a solitary lytic bone lesion, which may resolve following curettage, to a disseminated leukaemia-like disease with multiple organ involvement, which can be fatal. Despite considerable advances in our understanding of the disease, the aetiology ofLCH remains obsc
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Wang, Eddy Hsi Chun. "The pathogenesis of alopecia areata." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/51360.

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The development of a hair loss disease, alopecia areata (AA), is believed to be associated with the initiation of an autoimmune response triggered by the activation of cytotoxic T-cells (CTLs) by unidentified autoantigen epitopes. The long-term sequelae of AA also have not received investigation beyond clinical observations. I hypothesized that CTLs in AA can be activated by autoantigen epitopes derived from hair follicle (HF) cells and activated CTLs may affect the viability of HF keratinocytes. Furthermore, I hypothesized the development of AA can have adverse effects on heart health and in
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Books on the topic "Pathogenesis"

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M, Iglewski Barbara, and Clark Virginia L, eds. Molecular basis of bacterial pathogenesis. Academic Press, 1992.

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Kishore, Uday, ed. Microbial Pathogenesis. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-67452-6.

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Ağın, Başak, and Şafak Horzum. Posthuman Pathogenesis. Routledge, 2022. http://dx.doi.org/10.4324/9781003288244.

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Nordenfelt, Pontus, and Mattias Collin, eds. Bacterial Pathogenesis. Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-6673-8.

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Lee, Hong Kyu, Salvatore DiMauro, Masashi Tanaka, and Yau-Huei Wei, eds. Mitochondrial Pathogenesis. Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-662-41088-2.

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DeLeo, Frank R., and Michael Otto, eds. Bacterial Pathogenesis. Humana Press, 2008. http://dx.doi.org/10.1007/978-1-60327-032-8.

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Schuitemaker, Hanneke, and Frank Miedema, eds. AIDS Pathogenesis. Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-017-0685-8.

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Hanneke, Schuitemaker, and Miedema F, eds. AIDS pathogenesis. Kluwer Academic, 2000.

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1945-, Clark Virginia L., and Bavoil Patrik M, eds. Bacterial pathogenesis. Academic Press, 1997.

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1945-, Clark Virginia L., and Bavoil Patrik M, eds. Bacterial pathogenesis. Academic Press, 1994.

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Book chapters on the topic "Pathogenesis"

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Frank, J. Howard, J. Howard Frank, Michael C. Thomas, et al. "Pathogenesis." In Encyclopedia of Entomology. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6359-6_2799.

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Holmgren, Jan. "Pathogenesis." In Cholera. Springer US, 1992. http://dx.doi.org/10.1007/978-1-4757-9688-9_10.

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Heemskerk, Dorothee, Maxine Caws, Ben Marais, and Jeremy Farrar. "Pathogenesis." In SpringerBriefs in Public Health. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-19132-4_2.

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Chae, Jae Jin, and Daniel L. Kastner. "Pathogenesis." In Rare Diseases of the Immune System. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-14615-7_2.

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van Duinen, Martin Th A. "Pathogenesis." In The Transorbital Intracranial Penetrating Injury. Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-011-4457-5_8.

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Gonzalez-Scarano, F., M. J. Endres, and N. Nathanson. "Pathogenesis." In Current Topics in Microbiology and Immunology. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76018-1_8.

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Cheli, Rodolfo, Alessandro Perasso, and Attilio Giacosa. "Pathogenesis." In Gastritis. Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-71845-8_7.

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Modrow, Susanne, Dietrich Falke, Uwe Truyen, and Hermann Schätzl. "Pathogenesis." In Molecular Virology. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-20718-1_4.

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Bond, Ross. "Pathogenesis." In Veterinary Allergy. John Wiley & Sons, Ltd, 2013. http://dx.doi.org/10.1002/9781118738818.ch38.

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Poolman, Jan T. "Pathogenesis." In Gonococci and Meningococci. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-1383-7_96.

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Conference papers on the topic "Pathogenesis"

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Chen, Sihan, and Linshan Cao. "Deep Learning-Based Genetic Detection and Pathogenesis of Diabetes." In 2024 Fourth International Conference on Digital Data Processing (DDP). IEEE, 2024. https://doi.org/10.1109/ddp64453.2024.00011.

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"26th Annual Midwest Microbial Pathogenesis Conference (MMPC)." In 26th Annual Midwest Microbial Pathogenesis Conference (MMPC). Frontiers Media SA, 2020. http://dx.doi.org/10.3389/978-2-88963-591-7.

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Worcester, Elaine M., Andrew P. Evan, Fredric L. Coe, et al. "Pathogenesis of Stone Disease." In RENAL STONE DISEASE 2: 2nd International Urolithiasis Research Symposium. AIP, 2008. http://dx.doi.org/10.1063/1.2998058.

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Chen, Chang-Lin, Jia-Chen Tsai, Wei-Ling Huang, et al. "Mitochondria dynamics and pathogenesis." In PROCEEDINGS OF THE 3RD INTERNATIONAL SEMINAR ON METALLURGY AND MATERIALS (ISMM2019): Exploring New Innovation in Metallurgy and Materials. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0002464.

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Hybiske, Kevin. "PL09.1 Understanding chlamydia pathogenesis." In Abstracts for the STI & HIV World Congress (Joint Meeting of the 23rd ISSTDR and 20th IUSTI), July 14–17, 2019, Vancouver, Canada. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/sextrans-2019-sti.12.

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Chandran, Vinod. "Pathogenesis of Psoriatic Arthritis." In The 6th IFPA World Psoriasis and Psoriatic Arthritis Congress. Medicom Medical Publishers, 2023. http://dx.doi.org/10.55788/c9ea6682.

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Chandran, Vinod. "Pathogenesis of Psoriatic Arthritis." In 6th IFPA-WPPAC 2021. Medicom Medical Publishers, 2023. http://dx.doi.org/10.55788/d1cace39.

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Yoshida, Masahiro, Shunsuke Minagawa, Jun Araya, et al. "Involvement ferroptosis in COPD pathogenesis." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa4451.

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ZIEGLER, JOHN L. "INFECTIOUS AGENTS AND CANCER: PATHOGENESIS." In International Seminar on Nuclear War and Planetary Emergencies 38th Session. WORLD SCIENTIFIC, 2008. http://dx.doi.org/10.1142/9789812834645_0039.

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HARDY, JOHN. "ALZHEIMER'S DISEASE: GENETICS TO PATHOGENESIS." In International Seminar on Nuclear War and Planetary Emergencies 38th Session. WORLD SCIENTIFIC, 2008. http://dx.doi.org/10.1142/9789812834645_0035.

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Reports on the topic "Pathogenesis"

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Roop, R. M. Mid-Atlantic Microbial Pathogenesis Meeting. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada413150.

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Geisbert, Thomas W., Peter B. Jahrling, Tom Larsen, Kelly J. Davis, and Lisa Hensley. Filovirus Pathogenesis in Nonhuman Primates. Defense Technical Information Center, 2002. http://dx.doi.org/10.21236/ada421420.

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Altier, Craig, and Daniel Wozniak. Mid-Atlantic Microbial Pathogenesis Meeting. Defense Technical Information Center, 2005. http://dx.doi.org/10.21236/ada461976.

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Adami, Hans-Olov. The Infectious Pathogenesis of Prostate Cancer. Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada503532.

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Sood, Anil K. Early Events in Ovarian Cancer Pathogenesis. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada608121.

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Adami, Hans-Olov. The Infectious Pathogenesis of Prostate Cancer. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada526530.

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Sood, Anil K. Early Events in Ovarian Cancer Pathogenesis. Defense Technical Information Center, 2010. http://dx.doi.org/10.21236/ada542176.

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Adami, Hans-Olov, and Lorelei Mucci. The Infectious Pathogenesis Of Prostate Cancer. Defense Technical Information Center, 2011. http://dx.doi.org/10.21236/ada549351.

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Adami, Hans-Olov, and Lorelei A. Mucci. The Infectious Pathogenesis of Prostate Cancer. Defense Technical Information Center, 2008. http://dx.doi.org/10.21236/ada482578.

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Splitter, Gary, and Menachem Banai. Microarray Analysis of Brucella melitensis Pathogenesis. United States Department of Agriculture, 2006. http://dx.doi.org/10.32747/2006.7709884.bard.

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Original Objectives 1. To determine the Brucella genes that lead to chronic macrophage infection. 2. To identify Brucella genes that contribute to infection. 3. To confirm the importance of Brucella genes in macrophages and placental cells by mutational analysis. Background Brucella spp. is a Gram-negative facultative intracellular bacterium that infects ruminants causing abortion or birth of severely debilitated animals. Brucellosis continues in Israel, caused by B. melitensis despite an intensive eradication campaign. Problems with the Rev1 vaccine emphasize the need for a greater understand
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