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1

KATERGARI, Simoni A., Athanasios MILOUSIS, Olga PAGONOPOULOU, Byron ASIMAKOPOULOS, and Nikos K. NIKOLETTOS. "Ghrelin in Pathological Conditions." Endocrine Journal 55, no. 3 (2008): 439–53. http://dx.doi.org/10.1507/endocrj.k07-106.

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2

Yang, William Y., Ying Shao, Jahaira Lopez-Pastrana, Jietang Mai, Hong Wang, and Xiao-feng Yang. "Pathological conditions re-shape physiological Tregs into pathological Tregs." Burns & Trauma 3 (May 28, 2015): 1–11. http://dx.doi.org/10.1186/s41038-015-0001-0.

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Abstract CD4+FOXP3+ regulatory T cells (Tregs) are a subset of CD4 T cells that play an essential role in maintaining peripheral immune tolerance, controlling acute and chronic inflammation, allergy, autoimmune diseases, and anti-cancer immune responses. Over the past 20 years, a significant progress has been made since Tregs were first characterized in 1995. Many concepts and principles regarding Tregs generation, phenotypic features, subsets (tTregs, pTregs, iTregs, and iTreg35), tissue specificity (central Tregs, effector Tregs, and tissue resident Tregs), homeostasis (highly dynamic and apoptotic), regulation of Tregs by receptors for PAMPs and DAMPs, Treg plasticity (re-differentiation to other CD4 T helper cell subsets, Th1, Th2, Tfh, and Th17), and epigenetic regulation of Tregs phenotypes and functions have been innovated. In this concise review, we want to briefly analyze these eight new progresses in the study of Tregs. We have also proposed for the first time a novel concept that “physiological Tregs” have been re-shaped into “pathological Tregs” in various pathological environments. Continuing of the improvement in our understanding on this important cellular component about the immune tolerance and immune suppression would lead to the future development of novel therapeutics approaches for acute and chronic inflammatory diseases, allergy, allogeneic transplantation-related immunity, sepsis, autoimmune diseases, and cancers.
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3

Agasarov, L. G., M. Yu Gerasimenko, T. V. Konchugova, A. A. Maryanovsky, V. A. Drobyshev, E. S. Vasilyeva, G. I. Safiullina, et al. "Pharmacopuncture in common pathological conditions*." Russian Journal of Physiotherapy, Balneology and Rehabilitation 17, no. 4 (June 1, 2020): 219–24. http://dx.doi.org/10.18821/1681-3456-2018-17-4-219-224.

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Clinical recommendations have been developed based on the analysis of Russian and international experience in the use of pharmacopuncture which is a contemporary medical technology combining the therapeutic possibilities of reflex therapy and clinical pharmacology. The first part of the recommendations sets out general provisions on the document structure and content that meet the requirements of GOST R 56034-2014 Clinical recommendations (treatment protocols). * Pharmacopuncture in common pathological conditions: clinical recommendations. M., 2017 p. 39. Available at: https://docplayer.ru/53018894-Klinicheskie-rekomendacii-farmakopunktura-pri-rasprostranennyh-patologicheskih-sostoyaniyah.html. Link active on 06/15/2018.
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4

Leocani, Letizia, and Giancarlo Comi. "EEG Coherence in Pathological Conditions." Journal of Clinical Neurophysiology 16, no. 6 (November 1999): 548. http://dx.doi.org/10.1097/00004691-199911000-00006.

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5

Bruno, David W. "Pathological conditions of wild salmonids." Fisheries Research 17, no. 1-2 (June 1993): 1–2. http://dx.doi.org/10.1016/0165-7836(93)90002-o.

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6

Wijgaerts, Anouck, and Kathleen Freson. "Megakaryopoiesis under normal and pathological conditions." Hématologie 20, no. 6 (November 2014): 319–28. http://dx.doi.org/10.1684/hma.2014.0970.

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7

Milosevic, Dusanka, Ljiljana Janosevic, Ranko Dergenc, and Milan Vasic. "Pathological conditions associated with rhinitis medicamentosa." Srpski arhiv za celokupno lekarstvo 132, no. 1-2 (2004): 14–17. http://dx.doi.org/10.2298/sarh0402014m.

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Rhinitis medicamentosa (nose-drop-nose") is a term used for pathological condition of the nasal mucous membrane that results from long-term abuse with intranasal vasoconstrictors. The aim of this work was to examine what lead the patients with nosedropnose rhinitis to the initial usage of intranasal vasoactive drugs, in this prospective study, 92 patients with rhinitis medicamentosa were included. The evaluation of all study subjects comprised the history, ORL, microbiological and radiological examination, skin prick tests with a battery of routine respiratory and nutritive allergens and nasal cytology. The results of this study showed that the pathological conditions for initial use of intranasal vasoactive drugs were: acute upper respiratory infections in 293%, vasomotor rhinitis in 21.7%, allergic rhinitis in 16.3%, deviated nasal septum in 13.0%, nasal polyposis in 12%, rhinitis induced by mechanical trauma in 4.4%, and hormonal rhinitis in 3.3% of patients with rhinitis medicamentosa. In conclusion, the most common pathological conditions for developing rhinitis medicamentosa were chronic inflammatory and structural diseases manifested by permanent nasal obstruction as well as acute upper respiratory infections are.
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8

McCoy, J. Michael, and Daniel Oreadi. "Diagnosis and Management of Pathological Conditions." Journal of Oral and Maxillofacial Surgery 75, no. 8 (August 2017): e224-e263. http://dx.doi.org/10.1016/j.joms.2017.04.024.

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9

Carlson, Eric R., Ghali E. Ghali, and Kathleen E. Herb-Brower. "Diagnosis and Management of Pathological Conditions." Journal of Oral and Maxillofacial Surgery 70, no. 11 (November 2012): e232-e271. http://dx.doi.org/10.1016/j.joms.2012.07.037.

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10

Piombino-Mascali, Dario, Justina Kozakaitė, Algirdas Tamošiūnas, Ramūnas Valančius, Stephanie Panzer, and Rimantas Jankauskas. "Skeletal pathological conditions of Lithuanian mummies." Papers on Anthropology 23, no. 1 (July 1, 2014): 118. http://dx.doi.org/10.12697/poa.2014.23.1.10.

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11

Hansen, John-Erik S., Thorkild C. Bøg-Hansen, Bo Pedersen, and Keld Neland. "Microheterogeneity of orosomucoid in pathological conditions." Electrophoresis 10, no. 8-9 (1989): 574–78. http://dx.doi.org/10.1002/elps.1150100807.

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12

Augenlicht, Leonar. "4981783 Method for detecting pathological conditions." International Journal of Biochemistry 23, no. 11 (January 1991): iv. http://dx.doi.org/10.1016/0020-711x(91)90257-n.

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13

Lakhtakia, Akhlesh. "On pathological conditions and fresnel coefficients." International Journal of Infrared and Millimeter Waves 11, no. 12 (December 1990): 1407–13. http://dx.doi.org/10.1007/bf01013424.

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14

Baka, Zsuzsanna, Bence György, Pál Géher, Edit I. Buzás, András Falus, and György Nagy. "Citrullination under physiological and pathological conditions." Joint Bone Spine 79, no. 5 (October 2012): 431–36. http://dx.doi.org/10.1016/j.jbspin.2012.01.008.

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15

Nesci, Salvatore, and Giorgio Lenaz. "Impaired Mitochondrial Bioenergetics under Pathological Conditions." Life 12, no. 2 (January 29, 2022): 205. http://dx.doi.org/10.3390/life12020205.

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16

Kolur, Ashwini, Ashok M Patil, and Saeed Yendigiri. "Study of Mast Cells in Different Pathological Conditions of Surgically Resected Appendix." Indian Journal of Pathology: Research and Practice 8, no. 3 (2019): 251–53. http://dx.doi.org/10.21088/ijprp.2278.148x.8319.1.

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17

Pizov, A. V., N. A. Pizov, O. A. Skachkova, and N. V. Pizovа. "Endothelial function in normal and pathological conditions." Medical Council, no. 6 (April 28, 2019): 154–59. http://dx.doi.org/10.21518/2079-701x-2019-6-154-159.

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The article presents the data on the state of endothelial function in the normally and in various diseases and conditions. The basic functions of endothelium in modulation of vascular tone, atrombogenicity and thrombogenicity of the vascular wall, regulation of vascular wall adhesion, regulation of vascular growth are described. The main causes leading to the formation of endothelial dysfunction and the mechanisms underlying it are highlighted. Numerous studies on the evaluation of endothelial function in various diseases are presented. The basic methods of drug and non-drug correction of endothelial dysfunction are presented.
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18

Valenti, Maria, Luca Dalle Carbonare, and Monica Mottes. "Osteogenic Differentiation in Healthy and Pathological Conditions." International Journal of Molecular Sciences 18, no. 1 (December 27, 2016): 41. http://dx.doi.org/10.3390/ijms18010041.

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19

Lukina, EA, and AV Dezhenkov. "Iron Metabolism in Normal and Pathological Conditions." Clinical oncohematology 8, no. 4 (December 28, 2015): 355–61. http://dx.doi.org/10.21320/2500-2139-2015-8-4-355-361.

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20

Ribatti, Domenico. "The Boundary between Normal and Pathological Conditions." Critical Reviews in Eukaryotic Gene Expression 30, no. 6 (2020): 493–98. http://dx.doi.org/10.1615/critreveukaryotgeneexpr.2020036337.

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21

Yuana, Yuana, Auguste Sturk, and Rienk Nieuwland. "Extracellular vesicles in physiological and pathological conditions." Blood Reviews 27, no. 1 (January 2013): 31–39. http://dx.doi.org/10.1016/j.blre.2012.12.002.

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22

Hirashima, Mitsuomi, Yumiko Kashio, Nozomu Nishi, Akira Yamauchi, Tada-Atsu Imaizumi, Toshiro Kageshita, Naoki Saita, and Takanori Nakamura. "Galectin-9 in physiological and pathological conditions." Glycoconjugate Journal 19, no. 7-9 (2002): 593–600. http://dx.doi.org/10.1023/b:glyc.0000014090.63206.2f.

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23

Lopes, Joao P., and Paula Agostinho. "Cdk5: Multitasking between physiological and pathological conditions." Progress in Neurobiology 94, no. 1 (June 2011): 49–63. http://dx.doi.org/10.1016/j.pneurobio.2011.03.006.

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24

Koenker, Roger, and Stephen Portnoy. "Some pathological regression asymptotics under stable conditions." Statistics & Probability Letters 50, no. 3 (November 2000): 219–28. http://dx.doi.org/10.1016/s0167-7152(00)00107-3.

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25

Tedgui, A. "Endothelial permeability under physiological and pathological conditions." Prostaglandins, Leukotrienes and Essential Fatty Acids 54, no. 1 (January 1996): 27–29. http://dx.doi.org/10.1016/s0952-3278(96)90077-0.

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26

Baud, Stéphanie, Laurent Duca, Brigida Bochicchio, Bertrand Brassart, Nicolas Belloy, Antonietta Pepe, Manuel Dauchez, Laurent Martiny, and Laurent Debelle. "Elastin peptides in aging and pathological conditions." BioMolecular Concepts 4, no. 1 (February 1, 2013): 65–76. http://dx.doi.org/10.1515/bmc-2011-0062.

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AbstractElastin is the protein responsible for the resilience of vertebrate tissue. It is an extremely stable protein deposited during the early stages of life and experiencing almost no renewal. As a consequence, it can be considered that each individual has an elastin capital for life. Despite its extreme stability, elastin can be degraded by several enzymes termed elastases. Elastases are among the most aggressive proteases, and their presence is increased with age. As a consequence, elastin fragmentation resulting in the generation of elastin peptides is one of the hallmarks of aging. This review will examine their nature and further expose our current understanding of the role played by these peptides in aging and their contribution to tissue homeostasis and several pathologies.
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27

Hyodoh, Kazusa, Hideki Hyodoh, Hidenari Akiba, Mitsuharu Tamakawa, Noriko Nakamura, Naoya Yama, Takaharu Syonai, et al. "Brachial plexus: Normal anatomy and pathological conditions." Current Problems in Diagnostic Radiology 31, no. 5 (September 2002): 179–88. http://dx.doi.org/10.1067/mdr.2002.127636.

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28

Roos, Maria Augusta, Luisa Gennero, Tetyana Denysenko, Stefano Reguzzi, Giovanni Cavallo, Gian Piero Pescarmona, and Antonio Ponzetto. "Microparticles in physiological and in pathological conditions." Cell Biochemistry and Function 28, no. 7 (October 2010): 539–48. http://dx.doi.org/10.1002/cbf.1695.

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29

Xu, Jing, Peng Yu, Qian Yang, Jia-ning Meng, Jiao-jiao Shan, Qi-dong You, and Yi-qun Tang. "Antiarrhythmic Efficacy of CPUY11018 Under Pathological Conditions." Drug Development Research 74, no. 3 (January 16, 2013): 194–202. http://dx.doi.org/10.1002/ddr.21060.

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30

Leyendecker, Gerhard, Ludwig Wildt, Karl-August Brensing, and Claudia Roll. "Pulsatility of Serum LH in Pathological Conditions." Hormone Research 28, no. 2-4 (1987): 139–48. http://dx.doi.org/10.1159/000180937.

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31

Neve, Anna, Addolorata Corrado, and Francesco Paolo Cantatore. "Osteoblast physiology in normal and pathological conditions." Cell and Tissue Research 343, no. 2 (December 1, 2010): 289–302. http://dx.doi.org/10.1007/s00441-010-1086-1.

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32

Moal, Michel Le. "Individual vulnerabilities relative for potential pathological conditions." Brain Research 1645 (August 2016): 65–67. http://dx.doi.org/10.1016/j.brainres.2015.12.037.

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33

Grenier, Julie-Marthe, Peter J. Scordilis, David R. Seaman, and Michelle A. Wessely. "Lumbar MRI Part 2: Common pathological conditions." Clinical Chiropractic 9, no. 1 (March 2006): 39–47. http://dx.doi.org/10.1016/j.clch.2005.11.005.

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34

Kluczyński, Łukasz, Aleksandra Gilis-Januszewska, Magdalena Godlewska, Małgorzata Wójcik, Agata Zygmunt-Górska, Jerzy Starzyk, and Alicja Hubalewska-Dydejczyk. "Diversity of Pathological Conditions Affecting Pituitary Stalk." Journal of Clinical Medicine 10, no. 8 (April 14, 2021): 1692. http://dx.doi.org/10.3390/jcm10081692.

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Pituitary stalk lesions (PSL) are a very rare pathology. The majority of conditions affecting the infundibulum do not present with clinically apparent symptoms, what makes the diagnosis difficult. The recognition might be also complicated by the non-specific and transient characteristics of hormonal insufficiencies. In our study, we retrospectively analysed demographic, biochemical, and clinical long-term data of 60 consecutive, unselected adult patients (34 women and 26 men) with PSL diagnosed in the Department of Endocrinology, Jagiellonian University in Krakow. The diagnosis of PSL were categorized as confirmed, probable, or undetermined in 26, 26 and 8 patients, accordingly. Given the possible aetiology congenital, inflammatory, and neoplastic stalk lesions were diagnosed in 17, 15 and 20 patients, accordingly. In eight cases the underlying pathology remained undetermined. The most common pituitary abnormality was gonadal insufficiency diagnosed in 50.8% of cases. Diabetes insipidus was detected in 23.3% of cases. In 5% of patients the pituitary function recovered partially over time. Stalk lesions were extensively discussed in the context of the current literature. Based on the published data and our own experience a diagnostic algorithm has been proposed to help physicians with the management of patients with this challenging condition.
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35

Melhem, Hassan, Daniel Regan-Komito, and Jan Hendrik Niess. "Mucins Dynamics in Physiological and Pathological Conditions." International Journal of Molecular Sciences 22, no. 24 (December 20, 2021): 13642. http://dx.doi.org/10.3390/ijms222413642.

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Maintaining intestinal health requires clear segregation between epithelial cells and luminal microbes. The intestinal mucus layer, produced by goblet cells (GCs), is a key element in maintaining the functional protection of the epithelium. The importance of the gut mucus barrier is highlighted in mice lacking Muc2, the major form of secreted mucins. These mice show closer bacterial residence to epithelial cells, develop spontaneous colitis and became moribund when infected with the attaching and effacing pathogen, Citrobacter rodentium. Furthermore, numerous observations have associated GCs and mucus layer dysfunction to the pathogenesis of inflammatory bowel disease (IBD). However, the molecular mechanisms that regulate the physiology of GCs and the mucus layer remain obscured. In this review, we consider novel findings describing divergent functionality and expression profiles of GCs subtypes within intestinal crypts. We also discuss internal (host) and external (diets and bacteria) factors that modulate different aspects of the mucus layer as well as the contribution of an altered mucus barrier to the onset of IBD.
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36

Agasarov, L. G., M. Y. Gerasimenko, T. V. Konchugova, A. A. Maryanovsky, V. A. Dobryshev, E. S. Vasilyeva, G. I. Safiullina, et al. "Pharmacopuncture in common pathological conditions. Part 2." Russian Journal of Physiotherapy, Balneology and Rehabilitation 17, no. 5 (July 30, 2020): 284–96. http://dx.doi.org/10.17816/1681-3456-2018-17-5-284-296.

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In the previous issue (2018, No.4) of the journal, the first part of the clinical recommendations was published, which outlined general provisions on the structure and content of the document. The second part provides an algorithm for the use of pharmacopuncture for various categories of patients with different pathological conditions associated with dorsopathies.
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37

Harada, Atsuko, Natsuki Nakamura, and Takumi Yamanaka. "Peculiar Pathological Conditions in Pediatric Head Trauma." Japanese Journal of Neurosurgery 31, no. 4 (2022): 234–39. http://dx.doi.org/10.7887/jcns.31.234.

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38

ERDEMLİ KÖSE, Selinay Başak, Anıl YİRUN, Aylin BALCI, and Pınar ERKEKOĞLU. "RNA Damage and its Relationship with Pathological Conditions." Journal of Literature Pharmacy Sciences 9, no. 2 (2020): 184–96. http://dx.doi.org/10.5336/pharmsci.2019-72329.

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39

Sabaa, Bassma Mohamed El. "Pathological conditions predisposing to infertility and gynaecological neoplasia." World Journal of Obstetrics and Gynecology 3, no. 2 (2014): 28. http://dx.doi.org/10.5317/wjog.v3.i2.28.

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40

HASEGAWA, Tetsuo, and Masaru ISHII. "Visualizing bone tissue in homeostatic and pathological conditions." Proceedings of the Japan Academy, Series B 96, no. 2 (February 10, 2020): 43–49. http://dx.doi.org/10.2183/pjab.96.004.

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41

Manchester, Keith. "Identification of pathological conditions in human skeletal remains." Journal of Archaeological Science 14, no. 2 (March 1987): 227–28. http://dx.doi.org/10.1016/0305-4403(87)90009-4.

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42

Tőke, Judit, Attila Patócs, Péter Gergics, Rita Bertalan, Miklós Tóth, Károly Rácz, and Zsolt Tulassay. "Extracellular calcium sensing under normal and pathological conditions." Orvosi Hetilap 150, no. 17 (April 1, 2009): 781–90. http://dx.doi.org/10.1556/oh.2009.28602.

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Régóta ismert, hogy az ionos kalcium fontos sejten belüli másodlagos hírvivő szerepet tölt be. Az utóbbi 15 évben megismert kísérletes vizsgálatok és klinikai tanulmányok eredményei alapján az is egyértelművé vált, hogy az ionos kalcium elsődleges jelként is működik: az extracelluláris kalciumion egy G-fehérjéhez kapcsolódó sejtfelszíni receptort aktivál, amit kalciumérzékelő receptornak neveztek el. A szerzők összefoglalják a kalciumérzékelő receptor szerepét a kalciumhomeosztázis fenntartásában, ismertetik a receptor működésének szövetspecifikus sajátosságait és azokat a kórképeket, amelyek a kalciumérzékelés zavarával járnak. A kalciumérzékelő receptor génjének funkcióvesztést vagy fokozott működést okozó csírasejtes mutációi hyper- vagy hypocalcaemiával járó öröklődő betegségeket váltanak ki. Az inaktiváló hatású mutációk heterozigóta formában familiáris hypocalciuriás hypercalcaemiát, míg homozigóta formában a gyakran életet veszélyeztető újszülöttkori hyperparathyreosist okozzák. Az autoszomális domináns hypocalcaemia hátterében aktiváló mutációk állnak. A szerzők összefoglalják ezeknek a betegségeknek a klinikai és laboratóriumi jellemzőit és a kezelés lehetőségeit. Áttekintik azokat a molekuláris folyamatokat, amelyek primer és szekunder hyperparathyreosisos betegekben hibás kalciumérzékelést váltanak ki, valamint azokat a klinikai vizsgálatokat, amelyek a kalciumérzékelő receptorgén genetikai variációinak funkcionális következményeiről számolnak be.
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43

Szendi, István. "Delirium – a common complication of severe pathological conditions." Orvosi Hetilap 155, no. 48 (November 2014): 1895–901. http://dx.doi.org/10.1556/oh.2014.30049.

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Delirium is a complex syndrome caused most often by secondary neuronal dysfuncions due to systemic disorders. Because of the central nervous system manifestations of the general disease processes that are getting through the blood-brain barrier, the vigilance of attention flucutates and, therefore, the integration of incoming stimuli fails – resulting in inadequate behavioral answers. Delirium is one of the most common and serious complications of diseases, particularly in the elderly and patients in critical state. It cannot be traced back to a single etiologic process; one should consider all those pathophysiologic mechanisms that are interacting with one another simultaneously impairing the integrated functioning of the brain. Despite the high prevalence rate of delirium and the marked adverse effects on the outcome of the underlying disorders, management and therapy are basically lacking professional guidelines. The syndrome is a threatening state, requiring increased clinical attention and often intensive care. Beside evidence based therapeutic methods, conscious, targeted screening of the known risk factors and measures against them when they present themselves may exert remarkable influence on the prevention of delirium, which is also an exceptionally important aspect of the care of patients in critical state. Orv. Hetil., 2014, 155(48), 1895–1901.
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44

Villacorta-Lyew, Rachel, Brooks Laselle, Joseph P. Mazzoncini, Emily Merchant, and Peter J. Buckley. "Cardiac Pathological Conditions in Young Soldiers: Case Series." Military Medicine 173, no. 11 (November 2008): 1122–31. http://dx.doi.org/10.7205/milmed.173.11.1122.

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45

ALEXANDER, ROGER E., JOHN M. WRIGHT, and STAN THIEBAUD. "Evaluating, documenting and following up oral pathological conditions." Journal of the American Dental Association 132, no. 3 (March 2001): 329–35. http://dx.doi.org/10.14219/jada.archive.2001.0175.

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46

Kaneko, Naoko, and Kazunobu Sawamoto. "Adult neurogenesis and its alteration under pathological conditions." Neuroscience Research 63, no. 3 (March 2009): 155–64. http://dx.doi.org/10.1016/j.neures.2008.12.001.

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47

Dunér, Hans, and Bengt Pernow. "Histamine in Man under Physiological and Pathological Conditions." Acta Medica Scandinavica 168, no. 4 (April 24, 2009): 307–23. http://dx.doi.org/10.1111/j.0954-6820.1960.tb13452.x.

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48

Myagkova, M., V. Morozova, and S. Petrochenko. "Role natural autoantibodies in normal and pathological conditions." Immunopathology, Allergology, Infectology, no. 1 (January 1, 2016): 20–26. http://dx.doi.org/10.14427/jipai.2016.1.20.

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49

Ortner, Donald J., and Walter G. J. Putschar. "Identification of pathological conditions in human skeletal remains." Smithsonian Contributions to Anthropology, no. 28 (1985): 1–488. http://dx.doi.org/10.5479/si.00810223.28.1.

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50

Bernard-Kargar, C., and A. Ktorza. "Endocrine pancreas plasticity under physiological and pathological conditions." Diabetes 50, Supplement 1 (February 1, 2001): S30—S35. http://dx.doi.org/10.2337/diabetes.50.2007.s30.

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