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Dissertations / Theses on the topic 'Pathology and Forensic Medicine'

Author: Grafiati
Published: 9 July 2021
Last updated: 25 July 2025

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1

Ward, Jennifer. "Origins and development of forensic medicine and forensic science in England, 1823-1946." Thesis, n.p, 1993. http://ethos.bl.uk/.

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2

Fitrasanti, Berlian Isnia. "A study of drug use, pathology and post-mortem tissue distribution in the West of Scotland." Thesis, University of Glasgow, 2018. http://theses.gla.ac.uk/8695/.

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Drug abuse has always been a world problem. Recently people abuse both controlled and prescribed drugs. Opioids, cocaine, cannabis and amphetamines are the most widely abused drugs. The picture of the drug abuse problem in Scotland can be understood by an extensive study of drug prevalence and characteristics of drug use in the region. In drug-related deaths, post-mortem analysis, which includes autopsy and collecting samples for histological and toxicological analysis, is necessary to be carried out to investigate whether any drug has contributed to the cause of death. The samples which are c
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3

Westwood, Ellen Anne. "The use and outcomes of Dialectical Behaviour Therapy for forensic populations and non-forensic adolescent populations." Thesis, University of Birmingham, 2017. http://etheses.bham.ac.uk//id/eprint/7646/.

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Dialectical Behaviour Therapy (DBT) is a type of “talking therapy”, developed from cognitive behavioural therapy; it has been adapted to help people who experience emotions, often females diagnosed with Borderline Personality Disorder (BPD). With its growth in popularity, DBT has been adapted and used with other populations - not just adult females with BPD – to include forensic populations (i.e. people who are in contact with services due to criminal behaviour) and adolescent populations. This thesis contains a systematic literature review investigating the use of DBT in Forensic Services and
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4

Sturgess, Danielle. "Engagement in treatment amongst a forensic population." Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6559/.

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This thesis aims to provide a detailed understanding of treatment engagement amongst forensic populations. Following an introduction outlining the current theoretical thinking in the area, Chapter 2 presents a systematic literature review exploring reasons for completion/non-completion of treatment from an offender's perspective. Consensus regarding reasons for treatment completion/non-completion was found. Reasons provided supported the majority of factors outlined in the Multifactor Offender Readiness Model (MORM), a model of treatment readiness. Research in this area was limited; no papers
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5

Tiemensma, Marianne. "Sudden and unexpected deaths in adults : an investigation of cases reported to Tygerberg Forensic Pathology Services from January 2001 - December 2005." Thesis, Stellenbosch : University of Stellenbosch, 2010. http://hdl.handle.net/10019.1/5179.

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Thesis (MMed (Pathology. Forensic Medicine))--University of Stellenbosch, 2010.<br>Bibliography<br>ENGLISH ABSTRACT: Background - The workload of the forensic pathologist and Forensic Pathology Services staff is increased by the referral of potentially unnecessary natural cases to the Forensic Pathology Services. The primary aims of the medico-legal autopsy are limited to establishing a cause of death in presumed unnatural cases, and to exclude criminality or negligence. Objective – To determine the final outcomes of forensic post-mortem examinations in “sudden and unexpected” adult deat
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6

La, Grange Heleen. "Respiratory pathogens in cases of Sudden Unexpected Death in Infancy (SUDI) at Tygerberg forensic pathology service mortuary." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/86628.

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Thesis (MScMedSc)--Stellenbosch University, 2014.<br>ENGLISH ABSTRACT: Background: Sudden infant death syndrome (SIDS) is considered the second most frequent cause of infant mortality worldwide. Research specifically pertaining to SIDS is limited in the South African setting. Identifiable causes for sudden infant death remain challenging despite full medico-legal investigations inclusive of autopsy, scene visit and ancillary studies. Viral infections could contribute to some sudden unexpected death in infancy (SUDI) cases, especially since a multitude of respiratory viruses have been detected
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7

Battistini, A. "INTRAUTERINE FETAL DEATH: A FORENSIC-PATHOLOGY STUDY ABOUT THE ESTIMATION OF TIME OF DEATH." Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/229914.

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In forensic pathology is of fundamental importance the diagnosis of time of death. If such an investigation is often complex with a well-preserved corpse, it is even more difficult in the case of a fetus dead in-utero affected by macerative post-mortal phenomena. The criteria currently available in pathological and obstetrical literature date back to the '60s and '70s and focus on macro- and microscopic characteristics of fetus and placenta almost never scientifically validated. They can turn to be inappropriate or useless in clinical practice, where the medical examiner often experience a com
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8

Hlahla, Mmachuene I. "Discrepancies between antemortem computed tomography scan and autopsy findings of traumatic intracranial haemorrrhage at Pietersburg Hospital forensic pathology Department." Thesis, University of Limpopo, 2019. http://hdl.handle.net/10386/3050.

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Thesis (MMED. (Forensic Medicine)) --University of Limpopo, 2019<br>Traumatic intracranial haemorrhages are common, carry a high mortality rate and are therefore commonly known in the practice of forensic pathology as unnatural deaths. Studies have demonstrated a significant decrease in mortality rate among patients who received surgical interventions compared to patients who were treated medically. Missed or mis-diagnoses, which may be apparent during an autopsy procedure, present possible missed treatment opportunities. Aim/objective and methods The study investigated the discrepancy rate
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9

Paiva, Luiz Airton Saavedra de. ""Determinantes morfológicos da ação do fogo nos pulmões em autópsias forenses"." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/5/5144/tde-18082005-151358/.

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Análise semiquantitativa do parênquima distal de pulmões obtidos em autópsia de vítimas de morte por ação do fogo e por sufocação, foi feita para avaliar as alterações em bronquíolos e tecido alveolar (ductos e alvéolos). A análise discriminante dos parâmetros obtidos permitiu classificação de 74%<br>A semiquantitative analysis of the distal parenchyma in lung autopsies of victims of death by fire and death by suffocation, was done to evaluate the changes in membranous bronchiolar and alveolar tissue (alveolar ducts and alveoli). The discriminant parameters obtained permitted classification of
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10

Iwamura, Edna Sadayo Miazato. "Análise de DNA em osso humano: estudo qualitativo da microestrutura do osso compacto." Universidade de São Paulo, 2003. http://www.teses.usp.br/teses/disponiveis/5/5160/tde-03052004-153912/.

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Para a execução da etapa inicial da identificação médico-legal de restos humanos (antropometria e exame dos arcos dentários), faz-se necessária uma limpeza prévia da ossada, para a remoção de tecidos moles putrefeitos. Os casos não identificados por esses métodos tradicionais, poderão ser submetidos ao exame de DNA. No entanto, apesar do grande avanço da biologia molecular, utilizando a amplificação de DNA pela PCR, algumas limitações que afetam a habilidade de se obter DNA em restos humanos, permanecem. Dessa forma, o objetivo deste trabalho foi fornecer subsídios morfológicos para os analist
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11

BUGELLI, Valentina. "Multidisciplinary approach to minimun PMI estimation with a special focus on the entomological evidence." Doctoral thesis, Università degli studi del Molise, 2020. http://hdl.handle.net/11695/100940.

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Lo scopo del lavoro di tesi è stato quello di valutare l'affidabilità dei metodi entomologici per la stima del PMI, in comparazione con altri approcci investigativi proposti di recente quali: il decadimento delle proteine muscolari unitamente a sistemi di punteggio assegnati alle diverse modificazioni post-mortali. Nella prima parte il progetto di ricerca si è incentrato su alcune fasi critiche dell'indagine entomologica (repertazione, preparazione e conservazione del campione entomologico) per poi proseguire con una indagine in campo aperto con modello animale: • un primo studio ha valutato
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12

Pienaar, J. P. "Opname van opinie van regslui ten opsigte van doeltreffendheid van geregtelike post mortems in die Wes-Kaap." Thesis, Stellenbosch : Stellenbosch University, 2001. http://hdl.handle.net/10019.1/52386.

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Study project (M.Med.) -- University of Stellenbosch, 2001.<br>ENGLISH ABSTRACT: The main purpose in doing forensic post mortems is to supply information to the judicial system. Medical personnel involved in doing post mortems seldom get feedback regarding efficiency. Numerous allegations have been made regarding the work of district surgeons in terms of forensic post mortems, often suggesting that the work is substandard. In South Africa district surgeons do post mortems mostly in the rural areas, and training centre personnel do forensic post mortems in urban areas. Training centre p
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13

Chapman, Harriet. "Facial affect processing in violent offenders : a comparison of intimate partner violent and generally violent men." Thesis, University of Birmingham, 2016. http://etheses.bham.ac.uk//id/eprint/6979/.

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This thesis explores facial affect processing in violent offenders, with a specific focus on how patterns of impairment seen in Intimate Partner Violent (IPV) prisoners differ to those of other violent prisoners. Chapter one introduces IPV as a serious public health concern with inadequate treatment efficacy. It discusses the overlap between IPV and non-IPV violence and highlights the need for further research elucidating how the treatment needs of IPV prisoners differ to those of non-IPV prisoners. The role of facial affect processing is then discussed in relation to empathy and violent offen
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14

Salwani, Farah. "A socio-legal study on organ shortage in Malaysia." Thesis, University of Southampton, 2012. https://eprints.soton.ac.uk/341443/.

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Human organs are the most valuable gifts of life. Until today, through organ transplantation, thousands of lives have been saved and many more blessed with hope and happiness through a better quality of living. However, rapid developments in transplant technology will be meaningless if supply of the needed organs remains scarce and organ transplantation procedures cannot take place accordingly. This global problem of organ shortage is also faced by Malaysia. Despite campaigns and initiatives introduced by the Malaysian authorities, the problem remains unresolved and the situation is worsening.
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15

Martin, Bertha Louise. "High pressure liquid chromatography ion exchange studies on bile relating to the postmortem interval." Scholarly Commons, 1987. https://scholarlycommons.pacific.edu/uop_etds/2141.

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It is the purpose of this, then, to investigate the feasibility of using the changes of concentrations of small iconic decomposition products in bile as indicators of time since death. High pressure liquid chromatography was selected for measurement of these changes.
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16

Hartley, Louise Charlotte. "International differences in the clinical effectiveness of medical interventions : a study using 'panoramic' meta-analysis." Thesis, University of Birmingham, 2012. http://etheses.bham.ac.uk//id/eprint/3619/.

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Due to concerns about international differences in treatment effectiveness, many countries are reluctant to extrapolate overseas clinical data to form the basis of guideline recommendations and intervention approval processes. The evidence on which these concerns are based, however, comes from a limited dataset, with few studies directly assessing international differences in treatment effectiveness. This study aims to assess differences in the results of cardiovascular trials between Europe, North America, and Asia using the panoramic meta-analysis approach. All meta-analyses containing rando
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17

O'Regan, Karla Maureen. "Beyond illusion : a juridical genealogy of consent in criminal and medical law." Thesis, London School of Economics and Political Science (University of London), 2014. http://etheses.lse.ac.uk/934/.

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Consent is a concept used frequently and with great significance in a wide array of legal fields. It serves to regulate relationships, legitimize authority, delimit normality, and entrench idealized ways of being in the world. Yet despite the consequence of these functions, there is very little precision within legal scholarship about just what consent is. Few investigations of its definitional content depart from presumptive statements about personal autonomy. These associations are often described as the ‘common sense’ of consent and serve to secure a foundationalist discourse about what con
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18

Campbell, Lisa. "Do scores on the HCR-20 and FAM predict frequency of self-harm in females within a secure psychiatric hospital?" Thesis, University of Birmingham, 2017. http://etheses.bham.ac.uk//id/eprint/7698/.

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The thesis consists of two volumes. Volume 1: This volume consists of three chapters. The first chapter is a literature review examining whether there is a link between psychopathy and self-harm. The second chapter is a quantitative study investigating whether scores on the HCR-20 and FAM risk assessment tools predict frequency of self-harm in females within a secure psychiatric hospital. The third chapter comprises a public domain briefing document which provides a plain language summary of the literature review and empirical paper. Volume 2: This volume consists of five Forensic Clinical Pra
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19

CASTOLDI, ELISA. "ANALYSIS OF MARKERS OF DISEASE AND HEALTH STATUS ON HUMAN SKELETONS." Doctoral thesis, Università degli Studi di Milano, 2018. http://hdl.handle.net/2434/547155.

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One of the main aims of the forensic anthropological practice regards the proper identification of human remains. Years of studies and research provided many instruments for the reconstruction of the so-called “biological profile” (e.g. age at death, sex, stature, race); nevertheless, and despite the numerous information that it can provide, the pathological investigation of skeletons still displays many uncertainties. The identification of pathological signs from bones can in fact narrow the field of research in case of the recovery of unknown human remains, and can provide valuable data for
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20

Lourens, Denise. "The epidemiology, pathology and toxicology of suicide." Master's thesis, University of Cape Town, 1998. http://hdl.handle.net/11427/26780.

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Complete suicides and parasuicides are a major cause of death and disability in South Africa and the rest of the world. The epidemiology, pathology and toxicology of complete suicides were investigated in this study. All the complete suicide cases, which were presented to Salt River Medicolegal Laboratory over a period of one year (1 January 1997 - 31 December 1997), were analysed. The candidate personally conducted 148 of the alleged 180 suicide cases that presented in this time period (82%). The candidate did all the follow up investigations herself. The main findings were: 1. The male to fe
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21

Maistry, Sairita. "Retrospective analysis of deaths in the Table Mountain National Park 2000-2011." Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/15576.

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Includes bibliographical references<br>Background: The TMNP is one of the more famous of Cape Town's tourist attractions. Stretching across the Peninsula, this conservation site is home to rare indigenous flora and fauna, biodiverse habitats and the spectacular Table Mountain. Despite its seemingly safe infrastructure, there have been media reports of accidents and deaths that have occurred in the TMNP and on Table Mountain. Aim: To determine the number and types of fatalities in the TMNP from 2000-2011. Method: The Salt River Forensic Pathology Laboratory is a state mortuary which serves the
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22

Moller, Izelle. "Retrospective review of paediatrics patients involved in pedestrian vehicle accidents in greater cape Town." Master's thesis, Faculty of Health Sciences, 2021. http://hdl.handle.net/11427/32860.

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Pedestrian vehicle injuries are a growing public health threat worldwide. In South Africa, pedestrian accidents are the leading cause of injury related deaths in children younger than 15 years. There is international and national research looking at various aspects of pedestrian vehicle accidents. Previous studies have highlighted the general distribution of injuries sustained in paediatric pedestrian accidents. However, the specific types of injuries sustained by children pedestrians in different age groups have not been widely researched. We conducted a retrospective review of children invol
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23

Peddle, Laura. "Post-mortem organ weights at a South African mortuary." Master's thesis, Faculty of Health Sciences, 2019. http://hdl.handle.net/11427/30816.

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Background Weighing of organs is a necessary part of every autopsy and provides objective evidence of pathology, especially in forensic cases where histology is not always taken. Reference ranges must be locally applicable, accurate, and regularly defined. Aims The primary aim was generation of post-mortem organ weight reference ranges for use in South African mortuaries. Secondary aims were analysing factors influencing organ weights, and comparison of data to those from international populations. Methods A retrospective study was conducted using autopsy reports from the Salt River m
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24

Martin, Lorna Jean. "Violence against women : an analysis of the epidemiology and patterns of injury in rape homicide in Cape Town and in rape in Johannesburg." Master's thesis, Faculty of Health Sciences, 1999. http://hdl.handle.net/11427/30501.

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Violence against women is an important cause of morbidity and mortality in South Africa and indeed the of world. Women and men are equal and must have equal guarantees of economic, social, civil, political cultural rights. Women who are denied basic right security cannot participate equally in society. Violence denies this basic human right. This study is descriptive and a retrospective analysis of rape survivors in Johannesburg from 1992, a prospective analysis of homicide victims from Cape from mid-1996 to end 1998. The results have been analysed into demographic variables and compared to tr
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25

Afonso, Estevão Bernardo. "Deaths in police custody in the Cape Town Western Metropole 2000-2009." Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/16551.

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Includes bibliographical references<br>Deaths in police custody are a global phenomenon which continues to beset policing services worldwide. Research into these deaths has provided insight into the complexity of detention and led to the institution of preventative strategies which have seen a reduction in mortality internationally. An improved understanding of the South African detention milieu may similarly assist in reducing the mortality burden in this country. This study retrospectively reviewed deaths in custody in the Cape Town Western Metropole between 2000 and 2009, with the aim of id
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26

Molefe, Itumeleng. "Violence against women : epidemiology and pathology of femicides and suspected sexual homicides in Cape Town : a 10-year follow-up study." Master's thesis, University of Cape Town, 2016. http://hdl.handle.net/11427/20340.

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Background: Violence against women (VAW) is the most pervasive human rights abuse and a global health threat. The most extreme forms of physical and sexual violence are the intentional killing of a woman (femicide) and rape, or the combination of both in the form of r ape homicide, preferably termed 'sexual homicide' in this study. Motivation: Martin's research in 1999 reported a rape homicide incidence rate of 12.3/1000 female rapes reported to the police in Cape Town while the National study performed by Abrahams et al in 1999 reported an incidence rate of 10.9/1000 female rapes reported to
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27

Lukhozi, Sipho Michael. "Dual obligations in clinical forensic medicine." Thesis, Stellenbosch : Stellenbosch University, 2014. http://hdl.handle.net/10019.1/86537.

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Thesis (MPhil)--Stellenbosch University, 2014.<br>ENGLISH ABSTRACT: This thesis discusses ethical dilemmas faced by district surgeons in South Africa. District surgeons render clinical forensic services, which means that they deal mainly with detainees and victims of crime. The main functions of district surgeons are the collection of forensic evidence from patients and the care of detainees. So the focus is to assist in the administration of justice rather than improvement of patient wellbeing. The district surgeon may therefore find himself in a situation where patients’ interests are
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28

Duvall, Nicholas. "Forensic medicine in Scotland, 1914-39." Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/forensic-medicine-in-scotland-191439(7ca3afe7-7887-4133-9ba0-5206f2ea2237).html.

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This thesis examines the practice of forensic medicine in Scotland in the period 1914 to 1939. This was a time of significant dynamism for the discipline, in which it enjoyed a high public profile and played an important role in the investigation of crime. The project focuses in particular on medico-legal practice at an elite level, based in specialist departments in the universities of Edinburgh and Glasgow. As well as producing a significant amount of research and textbook material, and thus constituting authorities within the discipline, representatives of these institutions gave expert evi
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29

Tillmar, Andreas. "Populations and Statistics in Forensic Genetics." Doctoral thesis, Linköpings universitet, Institutionen för klinisk och experimentell medicin, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-54742.

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DNA has become a powerful forensic tool for solving cases such as linking a suspect to a crime scene, resolving biological relationship issues and identifying disaster victims. Traditionally, DNA investigations mainly involve two steps; the establishment of DNA profiles from biological samples and the interpreta-tion of the evidential weight given by theses DNA profiles. This thesis deals with the latter, with focus on models for assessing the weight of evidence and the study of parameters affecting these probability figures. In order to calculate the correct representative weight of DNA evide
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30

Lerer, Leonard Brian. "Forensic epidemiology : the interface between forensic science and public health." Master's thesis, University of Cape Town, 1994. http://hdl.handle.net/11427/25827.

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31

Derrico, Anthony Carl. "Voice of the Dead." ScholarWorks@UNO, 2004. http://scholarworks.uno.edu/td/181.

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32

Freeman, Michael. "The role of forensic epidemiology in evidence-based forensic medical practice." Doctoral thesis, Umeå universitet, Rättsmedicin, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-81434.

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Objectives This thesis is based on 4 papers that were all written with the same intent, which was to describe and demonstrate how epidemiologic concepts and data can serve as a basis for improved validity of probabilistic conclusions in forensic medicine (FM). Conclusions based on probability are common in FM, and the validity of probabilistic conclusions is dependant on their foundation, which is often no more than personal experience. Forensic epidemiology (FE) describes the use and application of epidemiologic methods and data to questions encountered in the practice of FM, as a means of pr
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33

De, Jong Jacqui Anne. "Investigating the effectiveness and efficiency of forensic pathology practice in Western Cape, South Africa." Master's thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/24882.

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Introduction: In South Africa (SA), the forensic sector faces significant challenges including how to meet increasing public expectations for high quality, reliable and valid scientific and medico legal results, whilst dealing with increasing caseloads and restricted resources in a developing country. Internationally, lean six-sigma and/or business-based frameworks have been developed to define, measure and analyse the efficiency, effectiveness and output of forensic laboratories, so as to assess performance to meet such challenges. Aim: This pilot project aimed to investigate the effectivenes
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Mutswangwa, Christopher T. "Evaluating the usability of an X-ray imaging system in forensic pathology." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29577.

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Post mortem imaging (PMI) is increasingly being adopted as an alternative to invasive autopsies in forensic pathology. PMI can be used as a sole technique or adjunct to an autopsy. The Lodox Xmplar-dr is an X-ray imaging system that has been adopted for use in PMI. The purpose of this study was to evaluate the perceived usability of this imaging system by focusing on the satisfaction of forensic pathologists in use of the system. Assessment of satisfaction was guided by the subjective satisfaction characteristics of likability, pleasure, comfort and trust. Incorporation of user needs into upda
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Williams, Graham Andrew. "Identification and resolution of capability gaps in forensic science." Thesis, University of Huddersfield, 2012. http://eprints.hud.ac.uk/id/eprint/17500/.

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Although forensic biology is a powerful tool in criminal investigations, there are a number of capability gaps; namely, the interpretation of low-level DNA mixtures, associating the DNA profile with a body fluid, and the issue of consent in sexual offences. A research strategy was developed that utilises whole genome amplification (WGA), messenger RNA and microRNA analysis, DNA profiling, and clothing damage analysis. An evaluation of a WGA technique – multiple displacement amplification - with and without a macromolecular crowding agent, indicated that this may be of use for DNA samples conta
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Al-Kandari, Nadiah M. J. "A forensic study of unnatural deaths in Kuwait : epidemiological, virtual autopsy and DNA investigations." Thesis, University of Central Lancashire, 2012. http://clok.uclan.ac.uk/6583/.

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Forensic science is growing rapidly in the world today. During the past decade, medico-legal investigations have been highly expanded to include all areas of forensic science. The present study investigated three important aspects of forensic biology. First, this present project investigated, a total number of 5,703 reported medico-legal cases diagnosed as un-natural deaths by The Forensic Department in Kuwait, during the year 2003-2009. The results show that accidental, homicidal and suicidal deaths accounted for 86%, 8% and 6%, respectively. The results showed that most people who died of un
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Abdou, Dalia Ahmed Selim Ali. "Three dimensional (3D) forensic facial reconstruction in an Egyptian population using computed tomography scanned skulls and average facial templates : a study examining subjective and objective assessment methods of 3D forensic facial reconstructions." Thesis, Queen Mary, University of London, 2018. http://qmro.qmul.ac.uk/xmlui/handle/123456789/41763.

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Forensic facial reconstruction can assist identification by reconstructing a face of the unknown person with the aim of its recognition by his/her family or friends. In the facial reconstruction approach adopted in this study, a 3D average face template was digitally warped onto a 3D scanned skull image. This study was carried out entirely on an Egyptian population, and was the first of its kind. Aims: This study aimed to demonstrate that 3D facial reconstructions using the novel methodology described could show significant resemblance to the faces corresponding to the persons in question when
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38

Vuko, Loyiso Abongile Marvin. "Post-mortem toxicogenetics: determining the suitable of blood samples collected for routine toxicological analyses for use in subsequent genetic analyses." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29525.

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South Africa has one of the highest prevalences of drug misuse and abuse in Africa. Salt River Mortuary (Cape Town, South Africa), along with other national Forensic Pathology Service providers, receives many cases of suspected drug-related deaths. In some cases, the traditional autopsy – when viewed together with the decedent's history – is not able to indicate whether a drug-related death is accidental or suicidal in relation to altered drug metabolism. Literature has shown that this can be investigated by sequencing gene(s) encoding the implicated metabolising enzyme(s) in a postmortem gene
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Vincent, Devin Michael. "Post-mortem Molecular Investigation: exploring genetic variation in CYP2D6 in deceased individuals at Salt River Mortuary." Master's thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29518.

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Drug use is a major burden in Cape Town, South Africa, and at times may be fatal. Individuals suspected to have demised from drug intoxication are referred for medico-legal investigation, in order for cause of death to be determined. Sometimes, it remains ambiguous as to whether the drug intoxication was suicidal or accidental, even after a full post-mortem examination. Literature has shown that molecular analysis of genetic variants in genes encoding for drug metabolising enzymes may provide insight into the manner of death. At Cape Town’s Salt River Mortuary, numerous toxicological-related c
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40

Horak, E. "Pathology of tumour cell host interactions." Thesis, University of Oxford, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379940.

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41

Mullen, Carrie. "Quality Assurance of forensic investigations in toxicology and traffic safety." Thesis, University of Glasgow, 2014. http://theses.gla.ac.uk/5465/.

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The work described in this thesis deals with three aspects of quality assurance in the field of forensic toxicology: proficiency testing schemes, validation of analytical methods for the piperazine group of abused drugs and validation of the police field impairment test, used at the roadside to test drivers for drug-induced impairment. Proficiency Testing: Long term reviews were performed for two forensic external quality assurance schemes. Rounds 30 (in 2007) to 48 (in 2012) of the UKAS-accredited commercial Quartz Forensic Blood Toxicology Proficiency Testing Scheme (PTS), and a ten year per
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42

A-Zanganeh, Mariam. "The assessment and management of violence in forensic populations." Thesis, University of Birmingham, 2009. http://etheses.bham.ac.uk//id/eprint/401/.

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The identification and management of individuals with a perceived high risk of future violence is of great priority for mental health professionals and the criminal justice system. The overall aim of this thesis is to examine the validity of the assessment and treatment of violence in forensic populations with a specific focus on the contribution of dynamic risk factors in predicting recidivism. Chapter One presents a conceptual literature review which provides an overview of the development of violence risk assessment approaches, and examines the predictive validity of dynamic factors in pred
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Kan, Man-yee Elsie. "Application of neisseria gonorrhoeae molecular typing techniques in forensic medicine." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B31971854.

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Kan, Man-yee Elsie, and 簡文意. "Application of neisseria gonorrhoeae molecular typing techniques in forensic medicine." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31971854.

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Savage, Anne Kay. "The pathology of hepatitis C virus infection." Thesis, University College London (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.362544.

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Mahmood, Tahir A. "The pathology and natural history of endometriosis." Thesis, University of Aberdeen, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277378.

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Endometriosis is a puzzling condition responsible for considerable morbidity. The literature is characterised by a large number of reports but there is surprisingly little agreement on the aetiology and pathophysiology. In particular the relationship between mild endometriosis and subfecundity is uncertain. The aim of the studies described in this thesis was to document the incidence, and symptomatology of endometriosis in the fertile and infertile population, to study the natural history of endometriosis in infertile women and to study folliculogenesis, fertilisation and pathophysiology of pe
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Takaichi, Kenichi. "Nail analysis in forensic toxicology for the detection of drug misuse." Thesis, University of Glasgow, 2004. http://theses.gla.ac.uk/3533/.

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This thesis examines the use of nail as an alternative biological specimen in forensic toxicology. Nail is a difficult analytical matrix from which to extract drugs because of its tough physical composition, based on keratin. The initial part of the project investigated the use of a cryogenic grinding method for fingernail clippings. Grinding at liquid nitrogen temperatures was found to be an effective procedure and the conditions were optimised to a two or three cycle programme of freezing and grinding. Small particle sizes were obtained of approximate size 1µm. It was established that drugs
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Ariffin, Marinah Mohd. "The application of novel extraction and analytical techniques in forensic toxicology." Thesis, University of Glasgow, 2006. http://theses.gla.ac.uk/4144/.

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The aim of this study was to investigate new methods of analysis which might be applied to forensic toxicology problems including those resulting from pesticides, particularly the quaternary ammonium herbicide group, and from drugs, particularly the benzodiazepine group. In the first part of this study, an efficient method for the determination of quaternary ammonium (QA) compounds (pesticides and drugs) in human whole blood was developed. The second part of this study concerned the development of a novel sorbents for solid phase extraction using molecularly imprinted polymers (MIPs). The appr
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Gustafsson, Tony. "Läkaren, döden och brottet : studier i den svenska rättsmedicinens etablering /." Uppsala : Acta Universitatis Upsaliensis : Uppsala universitetsbibliotek [distributör], 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8217.

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Lawrence, Petre John. "Aspects of hepatocyte function and structure after death : an investigation of liver glycogen and mitochondria during intra-corporal post-mortem storage." Thesis, University of Leeds, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.237072.

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