Academic literature on the topic 'Pathway elucidation'

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Journal articles on the topic "Pathway elucidation"

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Fairgrieve, Marian, Michael Davis, and Michael J. Gale. "Elucidation of the NLRP3 interactome." Journal of Immunology 196, no. 1_Supplement (2016): 62.7. http://dx.doi.org/10.4049/jimmunol.196.supp.62.7.

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Abstract Upon pathogen detection, the immune system triggers a variety of signaling pathways. Two key pathways are the proinflammatory NLRP3 inflammasome pathway, which activates the proinflammatory cytokines IL-1β and IL-18 via activation of Caspase-1 (CASP1), and the antiviral IFN pathway, which signals through the JAK-STAT pathway to upregulate key IFN-stimulated genes. Importantly, a growing body of evidence demonstrates that crosstalk between these pathways is required to fine tune the host immune response, and the co-regulation between the pathways can be either positive or negative. For
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Zhang, Hongyu, Ran Liu, Tingting Lou, Pei Zhao, and Suying Wang. "Pentostatin Biosynthesis Pathway Elucidation and Its Application." Fermentation 8, no. 9 (2022): 459. http://dx.doi.org/10.3390/fermentation8090459.

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Pentostatin (PNT), a nucleoside antibiotic with a 1,3-diazo ring structure, is distributed in several actinomycetes and fungi species. Its special structure makes PNT possess a wide spectrum of biological and pharmacological properties, such as antibacterial, antitrypanosomal, anticancer, antiviral, herbicidal, insecticidal, and immunomodulatory effects. Because of the promising adenosine deaminase inhibitory activity of PNT, its extensive application in the clinical treatment of malignant tumors has been extensively studied. However, the fermentation level of microbial-derived PNT is low and
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Han, Jianing, Emma Parker Miller, and Sijin Li. "Cutting-edge plant natural product pathway elucidation." Current Opinion in Biotechnology 87 (June 2024): 103137. http://dx.doi.org/10.1016/j.copbio.2024.103137.

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Ren, Dongliang, Enjie Diao, Hanxue Hou, and Haizhou Dong. "Degradation and ozonolysis pathway elucidation of deoxynivalenol." Toxicon 174 (January 2020): 13–18. http://dx.doi.org/10.1016/j.toxicon.2019.11.015.

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Gonçalves dos Santos, Karen Cristine, Fatima Awwad, Natacha Mérindol, and Isabel Desgagné-Penix. "From pathway to products: Canadian achievements in plant specialized metabolism." Genome 68 (January 1, 2025): 1–23. https://doi.org/10.1139/gen-2024-0099.

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Canada has made significant contributions to the field of plant biochemistry, with numerous researchers actively focusing on elucidating the biosynthetic pathways of plant specialized metabolites and producing these compounds in heterologous systems, such as bacteria, yeast, or other plant species. The review aims to highlight the strengths of Canadian research in this domain over the last three decades. It will describe advances in pathway elucidation, enzyme characterization, and production of enzymes and metabolites in heterologous systems, particularly in the areas of alkaloids, terpenoids
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Kitts, C. L., J. P. Lapointe, V. T. Lam, and R. A. Ludwig. "Elucidation of the complete Azorhizobium nicotinate catabolism pathway." Journal of Bacteriology 174, no. 23 (1992): 7791–97. http://dx.doi.org/10.1128/jb.174.23.7791-7797.1992.

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DAUPHIN-VILLEMANT, CHANTAL, CATHERINE BLAIS, and RENE LAFONT. "Towards the Elucidation of the Ecdysteroid Biosynthetic Pathway." Annals of the New York Academy of Sciences 839, no. 1 TRENDS IN COM (1998): 306–10. http://dx.doi.org/10.1111/j.1749-6632.1998.tb10781.x.

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Shao, Jie, Yuwei Sun, Haili Liu, and Yong Wang. "Pathway elucidation and engineering of plant-derived diterpenoids." Current Opinion in Biotechnology 69 (June 2021): 10–16. http://dx.doi.org/10.1016/j.copbio.2020.08.007.

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Chen, Junmin, Jianyong Chen, and Jingrong Lu. "Systematic Elucidation of the Mechanism of Oroxylum indicum via Network Pharmacology." Evidence-Based Complementary and Alternative Medicine 2020 (July 14, 2020): 1–8. http://dx.doi.org/10.1155/2020/5354215.

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Oroxylum indicum (O. indicum) is an important traditional Chinese medicine that exerts a wide spectrum of pharmacological activities. However, the pharmacological effect of O. indicum and its mechanism of action have not to be systematically elucidated yet. In this study, the druggability for active compounds of O. indicum was assessed via Traditional Chinese Medicine Systems Pharmacology Database (TCMSP), and the potential drug targets of O. indicum were identified using PharmMapper database. Additionally, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichmen
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Godden, B., A. S. Ball, P. Helvenstein, A. J. Mccarthy, and M. J. Penninckx. "Towards elucidation of the lignin degradation pathway in actinomycetes." Journal of General Microbiology 138, no. 11 (1992): 2441–48. http://dx.doi.org/10.1099/00221287-138-11-2441.

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Dissertations / Theses on the topic "Pathway elucidation"

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McCarty, Reid Michael. "Elucidation of the Biosynthetic Pathway for 7-Deazapurines." Diss., The University of Arizona, 2011. http://hdl.handle.net/10150/204334.

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Small molecules containing a 7-deazapurine moiety are ubiquitous in nature. They comprise a broad range of structurally diverse antibiotics produced by terrestrial and marine microorganisms that possess demonstrated antibiotic and antineoplastic activity. In addition, queuosine, a hypermodified nucleoside located in the wobble position of select tRNAs that is almost universally conserved throughout biology, contains a 7-deazapurine functional group. The since their initial identification over 50 years ago, the chemical transformations underlying the biosynthesis of 7-deazapurines have remained
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Sydor, Paulina K. "Elucidation of the prodiginine biosynthetic pathway in Streptomyces coelicolor A3(2)." Thesis, University of Warwick, 2010. http://wrap.warwick.ac.uk/3794/.

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The prodiginine antibiotics are produced by eubacteria, in particular members of the actinomycete family. Interest in this group of compounds has been stimulated by their antitumour, immunosuppressant and antimalarial activities at non-toxic levels. Streptomyces coelicolor A3(2) produces two prodiginines: undecylprodiginine and its carbocyclic derivative streptorubin B, which are both derived from the two intermediates 4-methoxy-2,2'-bipyrrole-5-carboxaldehyde (MBC) and 2-undecylpyrrole (2-UP). The red gene cluster of S. coelicolor contains 23 genes responsible for prodiginine biosynthesis. PC
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Zarrinkar, Patrick P. (Patrick Parvis). "Elucidation of the kinetic folding pathway of a Group I intron." Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/41368.

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Bhalara, Hiral Dolarbhai. "Elucidation of the biosynthetic pathway of a tripyrrole secondary metabolite, prodigiosin." Thesis, University of Cambridge, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.609352.

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Kilaru, Aruna, Richard Sante, Swati Swati, et al. "Elucidation of N-Acylethanolamine Pathway and Its Physiological Role in Physcomitrella Patens." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etsu-works/4804.

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Li, Yanyan. "Biosynthesis of butirosin : elucidation of the pathway to (2S)-4-amino-2-hydroxybutyric acid." Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614989.

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Rui, Yanning. "Elucidation of molecular mechanisms and biological functions of axin-mediated JNK pathway and p53 signaling /." View abstract or full-text, 2007. http://library.ust.hk/cgi/db/thesis.pl?BICH%202007%20RUI.

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Wan, Jun. "Elucidation of the JNK pathway mediated by Epstein-Barr virus encoded latent membrane protein 1 /." View abstract or full-text, 2004. http://library.ust.hk/cgi/db/thesis.pl?BICH%202004%20WAN.

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Thesis (Ph. D.)--Hong Kong University of Science and Technology, 2004.<br>Includes bibliographical references (leaves 105-128). Also available in electronic version. Access restricted to campus users.
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Jiang, Ming. "Elucidation of menaquinone biosynthesis in escherichia coli and explorative investigation of protein organization in the pathway /." View abstract or full-text, 2008. http://library.ust.hk/cgi/db/thesis.pl?CHEM%202008%20JIANG.

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Wu, Liming. "Elucidation of the NF-kB pathway mediated by Epstein - Barr virus-encoded latent membrane protein 1 (LMP1) /." View abstract or full-text, 2005. http://library.ust.hk/cgi/db/thesis.pl?BICH%202005%20WU.

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Books on the topic "Pathway elucidation"

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Potenski, Anna Michelle. Elucidating endothelial Caspase-9 signaling pathways in retinal vein occlusion. [publisher not identified], 2022.

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Gerner, Gwendolyn J., and Vera Joanna Burton. The Neurobiology of Encephalopathy of Prematurity. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0073.

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The risk of brain injury following premature birth increases with birth at earlier gestational ages and lower birthweights. The presentation of brain injury and subsequent neurodevelopmental sequelae in this population are extremely heterogeneous, as the injury is due to multifactorial causes; however, increasing amounts of research are elucidating the underlying mechanisms and pathways. This chapter broadly reviews the neurobiology of encephalopathy of prematurity, as well as clinical considerations, associated neurodevelopmental outcomes, and future directions in clinical care and research.
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Phillips, Andrew J. K. The function of sleep. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198778240.003.0003.

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The function of sleep was a longstanding mystery in neuroscience, but there is now compelling empirical evidence for several key functions of sleep. Elucidating these functions and their underlying pathways is a hot area for the field of sleep research today, and many open questions remain. What we have gleaned from recent data is that it is important to view sleep as a synthesis of processes that enable improved functioning during wakefulness. There is no single universal function of sleep, but rather a collection of synergistic functions that are each of varying importance to different speci
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Valdes, Ana M. Genetics. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0009.

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Epidemiological studies have demonstrated that osteoarthritis (OA) is a complex trait with numerous environmental and genetic risk factors. A great deal of effort has been spent elucidating these risk factors and progress has been made. It is clear however that the causes behind OA development and progression continue to remain largely elusive. Identification of those genes that, in conjunction with environmental factors, predispose to OA severity will lead to a better understanding of the mechanisms underlying disease development and thus promote improved health strategies for prevention. An
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Alexander, Jeffrey C., Ronald N. Jacobs, and Philip Smith, eds. The Oxford Handbook of Cultural Sociology. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780195377767.001.0001.

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This book examines the independent debates and modes of thought that have developed in the field of cultural sociology. It describes a variety of pathways for engaging in cultural sociology, all of which offer a template for elucidating the ways that meaning shapes social life. It offers an account of the origins of cultural sociology and how it has grown into the maturity it enjoys today, focusing on the so-called “cultural turn”—an epochal transformation in the human sciences—and the need to reflect on what could be learned from adjacent disciplines about cultural analysis. It also explores
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McKenzie, Alistair G. Historic timeline of obstetric anaesthesia. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198713333.003.0001.

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Foremost in the history of obstetric anaesthesia was the introduction of inhalational analgesia by James Simpson in 1847, first with ether and then chloroform. Nitrous oxide was first used in obstetrics in 1880. Neuraxial anaesthesia in obstetrics began with spinal block by Oskar Kreis in 1900, and within 25 years included pudendal, caudal, and paracervical blocks. From 1902 there was a vogue for ‘twilight sleep’, which remained in use until the 1950s. Spinal anaesthesia only became popular with the advent of procaine in 1905; favour declined in the United Kingdom from 1948 and did not return
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Book chapters on the topic "Pathway elucidation"

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Kaur, Charanpreet, Shweta Sharma, Sneh Lata Singla-Pareek, and Sudhir Kumar Sopory. "Methylglyoxal, Triose Phosphate Isomerase, and Glyoxalase Pathway: Implications in Abiotic Stress and Signaling in Plants." In Elucidation of Abiotic Stress Signaling in Plants. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2211-6_13.

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Brown, John M., Ilya Gridnev, and Jürgen Klankermayer. "Asymmetric Autocatalysis with Organozinc Complexes; Elucidation of the Reaction Pathway." In Topics in Current Chemistry. Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/128_2007_15.

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Amor Stander, Emily, Thomas Dugé de Bernonville, and Vincent Courdavault. "RNA-seq Analysis of Monoterpene Indole Alkaloid Biosynthetic Pathway Elucidation in Catharanthus roseus." In Methods in Molecular Biology. Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2349-7_9.

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Schmidt, Marco F. "Chemical Genetics: Validation of the Drug Target by Elucidation of the Signaling Pathway." In Chemical Biology. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-64412-6_15.

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Higashi, Richard M., Teresa W. M. Fan, Pawel K. Lorkiewicz, Hunter N. B. Moseley, and Andrew N. Lane. "Stable Isotope-Labeled Tracers for Metabolic Pathway Elucidation by GC-MS and FT-MS." In Methods in Molecular Biology. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1258-2_11.

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Sun, Jiayi, and Christie A. M. Peebles. "The Elucidation and Metabolic Engineering of Terpenoid Indole Alkaloid Pathway in Catharanthus roseus Hairy Roots." In Transgenesis and Secondary Metabolism. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-27490-4_14-1.

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Sun, Jiayi, and Christie A. M. Peebles. "The Elucidation and Metabolic Engineering of Terpenoid Indole Alkaloid Pathway in Catharanthus roseus Hairy Roots." In Reference Series in Phytochemistry. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-28669-3_14.

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Yamamoto, Yasuo. "Thorough Elucidation of Oxygenation- and Oxidation-Mechanisms of Iron(II) Porphyrin on the Basis of a New Hypothesis for an Electron-Transfer Pathway." In Oxygen Complexes and Oxygen Activation by Transition Metals. Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-0955-0_41.

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Das, Ritika, Amita Pandey, and Girdhar K. Pandey. "Signaling Pathways in Eukaryotic Stress, Aging, and Senescence: Common and Distinct Pathways." In Elucidation of Abiotic Stress Signaling in Plants. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2540-7_13.

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Cho, Joo Hyuk, and Kyung-Nam Kim. "CBL-Mediated Calcium Signaling Pathways in Higher Plants." In Elucidation of Abiotic Stress Signaling in Plants. Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2211-6_6.

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Conference papers on the topic "Pathway elucidation"

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Park, Minseong, Hegwon Chung, and Jiyong Kim. "Comparative Techno-economic Assessment of Hydrogen Production, Storage and Refueling Pathways." In Foundations of Computer-Aided Process Design. PSE Press, 2024. http://dx.doi.org/10.69997/sct.119682.

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Hydrogen, as a clean and versatile energy carrier, holds immense promise for addressing the world�s growing energy and environmental challenges. However, hydrogen-based energy systems face challenges related to efficient storage methods, energy-intensive production, refueling processes, and overall cost-effectiveness. To solve this problem, a superstructure was developed that integrates overall technologies related to hydrogen energy transportation. This study synthesizes process pathways for hydrogen energy transportation method including energy carrier production, storage, and refueling, bas
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Chiarella, Anna M., and Rustgi K. Rustgi. "Abstract A06: Elucidation of the extracellular adenosine pathway in metastatic pancreatic cancer." In Abstracts: AACR Special Conference on Pancreatic Cancer: Advances in Science and Clinical Care; September 6-9, 2019; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.panca19-a06.

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Sequeira, María Alejandra, Marcos J. Lo Fiego, Juan Daniel Coria, María Julia Castro, and María Belén Faraoni. "Identification of Vitamin D3 Hydroxylated Metabolites in Solanum glaucophyllum Leaves: Towards Its Biosynthetic Pathway Elucidation." In ECSOC-25. MDPI, 2021. http://dx.doi.org/10.3390/ecsoc-25-11686.

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Coffinet, S., L. Mühlena, J. Lipp, C. Neubauer, and K. Hinrichs. "Elucidation of the Biosynthetic Pathway of Butanetriol Dialkyl Glycerol Tetraethers Reveals a Novel Energy-Saving Adaptation." In 30th International Meeting on Organic Geochemistry (IMOG 2021). European Association of Geoscientists & Engineers, 2021. http://dx.doi.org/10.3997/2214-4609.202134101.

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Huelsewig, Carolin, Martin Goette, Christof Bernemann, et al. "Abstract 3024: Elucidation of WNT signaling pathway players “sFRP-1” and “TCF7L2” as novel potential biomarkers of triple negative breast cancer." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-3024.

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Hussein, Ola, Feras Alali, Ala‐Eddin Al Mustafa, and Ashraf Khalil. "Development of Novel Chalcone Analogs as Potential Multi-Targeted Therapies for Castration-Resistant Prostate Cancer." In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2021. http://dx.doi.org/10.29117/quarfe.2021.0114.

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Prostate cancer (PCa) is the second most frequently diagnosed malignancy, as well as a leading cause of cancer-related mortality in men globally. Despite the initial response to hormonal targeted therapy, the majority of patients ultimately progress to a lethal form of the disease, castration-resistant prostate cancer (CRPC). Therefore, the objective of this study was to discover and develop novel treatment modalities for CRPC. Chalcones are among the highly attractive scaffolds being investigated for their antitumor activities. A library of 26 chalcone analogs were designed, synthesized and e
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Ke, Rong, Navin Viswakarma, Kanchan Vishnoi, Sandeep Kumar, Ajay Rana, and Basabi Rana. "Abstract 108: Elucidation of MLK3-induced signaling pathways in hepatocellular carcinoma." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-108.

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Dalli, Jesmond, Ana Rodriguez, Bernd Spur, and Charles Serhan. "Structure elucidation and biological evaluations of sulfido-conjugated specialized pro-resolving mediators." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/mqgv6628.

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Inflammatory diseases are characterized by unabated inflammation that leads tissue destruction resulting in malaise. Whilst much is known on the mechanism that perpetuate inflammation, less is known about the molecules and pathways that coordinate the termination of inflammation and facilitate the repair and regeneration of damaged tissues. To evaluate the potential contribution of essential fatty acid-derived mediators in coordinating this life saving response we interrogated inflammatory exudates obtained following self-limited inflammatory challenge. Using radio-isotope tracking we found th
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Hyden, Brennan. "Elucidating genetic pathways of sex determination and dimorphism in Salix purpurea." In ASPB PLANT BIOLOGY 2020. ASPB, 2020. http://dx.doi.org/10.46678/pb.20.1372260.

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Dhamija, Shaina, and Arijit K. De. "Elucidating Competing Twisting and Isomerization Pathways in a Push-pull Stilbene." In Frontiers in Optics. Optica Publishing Group, 2022. http://dx.doi.org/10.1364/fio.2022.jw4b.73.

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We explore dielectric-controlled excited-state dynamics of a push-pull stilbene undergoing twisting and/or isomerization and demonstrate how global analysis of pump-probe data aids in elucidating involvement of interconverting conformers and/or isomers, often obscured in single-wavelength kinetics.
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Reports on the topic "Pathway elucidation"

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Fridman, Eyal, and Eran Pichersky. Tomato Natural Insecticides: Elucidation of the Complex Pathway of Methylketone Biosynthesis. United States Department of Agriculture, 2009. http://dx.doi.org/10.32747/2009.7696543.bard.

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Plant species synthesize a multitude of specialized compounds 10 help ward off pests. and these in turn may well serve as an alternative to synthetic pesticides to reduce environmental damage and health risks to humans. The general goal of this research was to perform a genetic and biochemical dissection of the natural-insecticides methylketone pathway that is specific to the glandular trichomes of the wild species of tomato, Solanumhabrochaites f. glabratum (accession PI126449). Previous study conducted by us have demonstrated that these compounds are synthesized de novo as a derivate pathway
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Matthews, Lisa, Guanming Wu, Robin Haw, et al. Illuminating Dark Proteins using Reactome Pathways. Reactome, 2022. http://dx.doi.org/10.3180/poster/20221027matthews.

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Diseases are often the consequence of proteins or protein complexes that are non-functional or that function improperly. An active area of research has focused on the identification of molecules that can interact with defective proteins and restore their function. While 22% percent of human proteins are estimated to be druggable, less than fifteen percent are targeted by FDA-approved drugs, and the vast majority of untargeted proteins are understudied or so-called "dark" proteins. Elucidation of the function of these dark proteins, particularly those in commonly drug-targeted protein families,
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Rafaeli, Ada, Wendell Roelofs, and Anat Zada Byers. Identification and gene regulation of the desaturase enzymes involved in sex-pheromone biosynthesis of pest moths infesting grain. United States Department of Agriculture, 2008. http://dx.doi.org/10.32747/2008.7613880.bard.

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The original objectives of the approved proposal included: 1. Establishment of the biosynthetic pathways for pheromone production using labeled precursors and GC-MS. 2. The elucidation of a circadian regulation of key enzymes in the biosynthetic pathway. 3. The identification, characterization and confirmation of functional expression of the delta-desaturases. 4. The identification of gene regulatory processes involved in the expression of the key enzymes in the biosynthetic pathway. Background to the topic: Moths constitute one of the major groups of pest insects in agriculture and their repr
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Lewinsohn, Efraim, Eran Pichersky, and Shimon Gepstein. Biotechnology of Tomato Volatiles for Flavor Improvement. United States Department of Agriculture, 2001. http://dx.doi.org/10.32747/2001.7575277.bard.

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The main objectives of the research project were: 1. The manipulation, by genetic engineering techniques, of the terpenoid pathway in tomato fruit. Specifically, to test the hypothesis whether overexpression of linalool synthase in tomato fruits will result in the diversion of intermediates of the carotene biosynthetic pathway to linalool, demonstrating that linalool synthase is a key regulatory enzyme, and possibly improving tomato flavor. 2. The elucidation of the biochemical pathway leading to eugenol and methyl eugenol, and the manipulation of this pathway to determine key enzymes and to i
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Dickman, Martin B., and Oded Yarden. Involvement of the PKA and MAPK signal transduction pathways in sclerotial morphogenesis in Sclerotinia sclerotiorum. United States Department of Agriculture, 2007. http://dx.doi.org/10.32747/2007.7695861.bard.

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The long-term goals of our research are to understand the regulation of sclerotial development and pathogenicity in S. sclerotiorum. The focus in this project is on the elucidation of the signaling events and environmental cues involved in the regulation of these processes, utilizing and continuously developing tools our research groups have established and/or adapted for analysis of S. sclerotiorum. Our stated specific objectives were to: 1. Follow activities and function of S. sclerotiorumPKA. 2. Identify and functionally evaluate effectors of the S. sclerotiorumERK-likeMAPK signaling pathwa
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Friedman, Haya, Julia Vrebalov, and James Giovannoni. Elucidating the ripening signaling pathway in banana for improved fruit quality, shelf-life and food security. United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7594401.bard.

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Background : Banana being a monocot and having distinct peel and pulp tissues is unique among the fleshy fruits and hence can provide a more comprehensive understanding of fruit ripening. Our previous research which translated ripening discoveries from tomato, led to the identification of six banana fruit-associated MADS-box genes, and we confirmed the positive role of MaMADS1/2 in banana ripening. The overall goal was to further elucidate the banana ripening signaling pathway as mediated by MADS-boxtranscriptional regulators. Specific objectives were: 1) characterize transcriptional profiles
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Guinney, Justin. Hierarchical and Multiscale Modeling for Elucidating the Androgren Receptor Signaling Pathway in Prostate Cancer. Defense Technical Information Center, 2009. http://dx.doi.org/10.21236/ada541199.

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Schetselaar, E. M., G. Bellefleur, and J. A. Craven. Elucidating VMS mineralizing fluid pathways from the geophysical responses to hydrothermal alteration. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2017. http://dx.doi.org/10.4095/299637.

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Tucker, Mark L., Shimon Meir, Amnon Lers, Sonia Philosoph-Hadas, and Cai-Zhong Jiang. Elucidation of signaling pathways that regulate ethylene-induced leaf and flower abscission of agriculturally important plants. United States Department of Agriculture, 2012. http://dx.doi.org/10.32747/2012.7597929.bard.

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Abstract:
The Problem: Abscission is a highly regulated process, occurring as a natural terminal stage of development, in which various organs are separated from the parent plant. In most plant species, the process is initiated by a decrease in active auxin in the abscission zone (AZ) and an increase in ethylene, and may be accelerated by postharvest or environmental stresses. Another potential key regulator in abscission is IDA (Inflorescence Deficient in Abscission), which was identified as an essential peptide signal for floral organ abscission in Arabidopsis. However, information is still lacking re
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Tian, Li, Rachel Amir, Doron Holland, and Hamutal Borochov-Neori. Elucidating the genetic pathways involved in shikimate, anthocyanin and hydrolyzable tannin accumulation in pomegranate. United States Department of Agriculture, 2015. http://dx.doi.org/10.32747/2015.7600023.bard.

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