Relevant bibliographies by topics / Pathways

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Pathways'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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Journal articles on the topic "Pathways"

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Šindelář, L., and M. Šindelářová. "Regulation of metabolic pathways PVY-RNA biosynthesis in tobacco: glycolytic pathway." Plant Protection Science 40, No. 3 (2010): 101–6. http://dx.doi.org/10.17221/991-pps.

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Tobacco plants infected with potato virus <I>Y</I> were studied at the stage of acute infection. Key enzymes of the glycolytic pathway, their regulation and the content of involved intermediates were monitored. The activities of the key enzymes of the glycolytic pathway (6-phosphofructokinase, fructosebisphosphatase and pyruvate kinase), determined in both crude homogenates and after partial purification, did not differ from the activities found in healthy control tissues. In virus-infected tissues the content of ATP was higher than in the healthy control. The levels of ADP and AMP
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Karatzas, Evangelos, Margarita Zachariou, Marilena M. Bourdakou, et al. "PathWalks: identifying pathway communities using a disease-related map of integrated information." Bioinformatics 36, no. 13 (2020): 4070–79. http://dx.doi.org/10.1093/bioinformatics/btaa291.

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Abstract Motivation Understanding the underlying biological mechanisms and respective interactions of a disease remains an elusive, time consuming and costly task. Computational methodologies that propose pathway/mechanism communities and reveal respective relationships can be of great value as they can help expedite the process of identifying how perturbations in a single pathway can affect other pathways. Results We present a random-walks-based methodology called PathWalks, where a walker crosses a pathway-to-pathway network under the guidance of a disease-related map. The latter is a gene n
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Midford, Peter E., Mario Latendresse, Paul E. O’Maille, and Peter D. Karp. "Using Pathway Covering to Explore Connections among Metabolites." Metabolites 9, no. 5 (2019): 88. http://dx.doi.org/10.3390/metabo9050088.

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Interpreting changes in metabolite abundance in response to experimental treatments or disease states remains a major challenge in metabolomics. Pathway Covering is a new algorithm that takes a list of metabolites (compounds) and determines a minimum-cost set of metabolic pathways in an organism that includes (covers) all the metabolites in the list. We used five functions for assigning costs to pathways, including assigning a constant for all pathways, which yields a solution with the smallest pathway count; two methods that penalize large pathways; one that prefers pathways based on the path
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Li, Chaoxing, Li Liu, and Valentin Dinu. "Pathways of topological rank analysis (PoTRA): a novel method to detect pathways involved in hepatocellular carcinoma." PeerJ 6 (April 9, 2018): e4571. http://dx.doi.org/10.7717/peerj.4571.

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Complex diseases such as cancer are usually the result of a combination of environmental factors and one or several biological pathways consisting of sets of genes. Each biological pathway exerts its function by delivering signaling through the gene network. Theoretically, a pathway is supposed to have a robust topological structure under normal physiological conditions. However, the pathway’s topological structure could be altered under some pathological condition. It is well known that a normal biological network includes a small number of well-connected hub nodes and a large number of nodes
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Lomberk, Gwen, and Raul Urrutia. "Primers on Molecular Pathways — Caspase Pathway." Pancreatology 9, no. 1-2 (2009): 6–8. http://dx.doi.org/10.1159/000178860.

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Fan, Wufeng, Yuhan Zhou, and Hao Li. "Pathway Interaction Network Analysis Identifies Dysregulated Pathways in Human Monocytes Infected by Listeria monocytogenes." Computational and Mathematical Methods in Medicine 2017 (2017): 1–8. http://dx.doi.org/10.1155/2017/3195348.

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In our study, we aimed to extract dysregulated pathways in human monocytes infected by Listeria monocytogenes (LM) based on pathway interaction network (PIN) which presented the functional dependency between pathways. After genes were aligned to the pathways, principal component analysis (PCA) was used to calculate the pathway activity for each pathway, followed by detecting seed pathway. A PIN was constructed based on gene expression profile, protein-protein interactions (PPIs), and cellular pathways. Identifying dysregulated pathways from the PIN was performed relying on seed pathway and cla
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Shao, Min. "Construction of an miRNA-Regulated Pathway Network Reveals Candidate Biomarkers for Postmenopausal Osteoporosis." Computational and Mathematical Methods in Medicine 2017 (2017): 1–9. http://dx.doi.org/10.1155/2017/9426280.

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We aimed to identify risk pathways for postmenopausal osteoporosis (PMOP) via establishing an microRNAs- (miRNA-) regulated pathway network (MRPN). Firstly, we identified differential pathways through calculating gene- and pathway-level statistics based on the accumulated normal samples using the individual pathway aberrance score (iPAS). Significant pathways based on differentially expressed genes (DEGs) using DAVID were extracted, followed by identifying the common pathways between iPAS and DAVID methods. Next, miRNAs prediction was implemented via calculating TargetScore values with precomp
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Loeber, Rolf, Phen Wung, Kate Keenan, et al. "Developmental pathways in disruptive child behavior." Development and Psychopathology 5, no. 1-2 (1993): 103–33. http://dx.doi.org/10.1017/s0954579400004296.

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AbstractDevelopmental sequences in disruptive behavior from childhood to adolescence are traced retrospectively and prospectively in two community samples of boys. Three developmental pathways are distinguished: (a) an early authority conflict pathway, consisting in sequence of stubborn behavior, defiance, and authority avoidance; (b) a covert pathway, consisting of minor covert behaviors, property damage, and moderate to serious forms of delinquency; and (c) an overt pathway, consisting of aggression, fighting, and violence. The overlap among the three disruptive pathways is examined. Those b
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Pian, Cong, Guangle Zhang, Libin Gao, Xiaodan Fan, and Fei Li. "miR+Pathway: the integration and visualization of miRNA and KEGG pathways." Briefings in Bioinformatics 21, no. 2 (2019): 699–708. http://dx.doi.org/10.1093/bib/bby128.

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Abstract miRNAs represent a type of noncoding small molecule RNA. Many studies have shown that miRNAs are widely involved in the regulation of various pathways. The key to fully understanding the regulatory function of miRNAs is the determination of the pathways in which the miRNAs participate. However, the major pathway databases such as KEGG only include information regarding protein-coding genes. Here, we redesigned a pathway database (called miR+Pathway) by integrating and visualizing the 8882 human experimentally validated miRNA-target interactions (MTIs) and 150 KEGG pathways. This datab
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Visakh, R., and K. A. Abdul Nazeer. "Identifying epigenetically dysregulated pathways from pathway–pathway interaction networks." Computers in Biology and Medicine 76 (September 2016): 160–67. http://dx.doi.org/10.1016/j.compbiomed.2016.06.030.

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Dissertations / Theses on the topic "Pathways"

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Konrad, Attila. "Investigation of Pathway Analysis Tools for mapping omics data to pathways." Thesis, Malmö högskola, Fakulteten för teknik och samhälle (TS), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-20843.

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Detta examensarbete granskar analysverktyg ur ett tvärvetenskapligt perspektiv. Det finns en hel del olika analysverktyg idag som analyserar specifika typer av omik data och därför undersöker vi hur många det finns samt vad de kan göra. Genom att definiera ett antal specifika krav såsom hur många typer av omik data den kan hantera, noggrannhet av verktygets analys så kan man se vilka som är mest lämpliga analysverktygen när det gäller kartläggning av omik data. Resultaten visar att det idag inte finns analysverktyg som uppfyller de specifikt angivna kraven eller huvudsyftet genom testning av p
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Soh, Donny. "Understanding pathways." Thesis, Imperial College London, 2011. http://hdl.handle.net/10044/1/6399.

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The challenge with todays microarray experiments is to infer biological conclusions from them. There are two crucial difficulties to be surmounted in this challenge:(1) A lack of suitable biological repository that can be easily integrated into computational algorithms. (2) Contemporary algorithms used to analyze microarray data are unable to draw consistent biological results from diverse datasets of the same disease. To deal with the first difficulty, we believe a core database that unifies available biological repositories is important. Towards this end, we create a unified biological datab
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Gupta, Apoorv. "Dynamic regulation of bacterial metabolic pathways using autonomous, pathway-independent control strategies." Thesis, Massachusetts Institute of Technology, 2017. http://hdl.handle.net/1721.1/112511.

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Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biological Engineering, 2017.<br>Cataloged from PDF version of thesis.<br>Includes bibliographical references (pages 86-91).<br>Metabolic engineering efforts have so far focused on strain optimization through careful metabolic modeling and tinkering with host genomes, through gene knockouts or knockins, to direct flux in desired channels. These efforts have borne fruit with the development of large manufacturing processes for numerous chemicals. The next challenge for metabolic engineering, however, lies in tackling issues as
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Burwitz, Martin. "Integrated Clinical Pathways." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2018. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-226773.

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Against the background of increasing multidisciplinarity as well as the focus on quality, transparency and economic efficiency of medical services, clinical pathways (CPs) have been established as a promising tool at the organizational level in recent years. They are primarily intended to ensure an adequate description of the care processes and to manage the balance between best treatment practice and economic viability. CPs standardize the internal care services by explicating the institution-specific knowledge with regard to recommendations for action, service portfolio, organizational struc
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Barrett, Susan, and N/A. "Pathways to Detention." Griffith University. School of Criminology and Criminal Justice, 2007. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20070824.112806.

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This research utilised a range of deterministic and stochastic analyses to establish whether Queensland's juvenile justice system processes Aboriginal and non-Aboriginal young male offenders differently. The impetus for this research stemmed from the continued high rates of Aboriginal over-representation within Australia's criminal justice system, despite diversionary measures to reduce such over-representation, and a commitment by the Queensland Government to reduce by 50% the number of Aboriginal peoples in custody by the year 2011. There are two competing hypotheses concerning the cause of
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Dhillon, Ravinder. "Diagnostic imaging pathways." University of Western Australia. School of Medicine and Pharmacology, 2007. http://theses.library.uwa.edu.au/adt-WU2007.0126.

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[Truncated abstract] Hypothesis: There is deficiency in the evidence base and scientific underpinning of existing diagnostic imaging pathways (DIP) for diagnostic endpoints. Objective: a) To carry out systematic review of literature in relation to use of diagnostic imaging tests for diagnosis and investigation of 78 common clinical problems, b) To identify deficiencies and controversies in existing diagnostic imaging pathways, and to develop a new set of consensus based pathways for diagnostic imaging (DIP) supported by evidence as an education and decision support tool for hospital based doct
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Dalgleish, Alison. "Pathways to principalship." AUT University, 2010. http://hdl.handle.net/10292/935.

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A qualitative descriptive approach was undertaken to research what was available within the areas of advice and guidance for potential principals who wish to achieve the position of principal at secondary schools in Aotearoa New Zealand. The literature review for this study uncovered very little in the way of New Zealand-based professional advice and guidance for potential principals, despite there being some leadership development programmes such as the Principal Preparation Programmes for Aspiring Principals (University of Auckland, Centre for Educational Leadership). However, the internatio
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Al, Hashemi Hamed. "Pathways to diversification." Thesis, Cranfield University, 2016. http://dspace.lib.cranfield.ac.uk/handle/1826/11694.

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A fundamental research question in regional economic development, is why some regions are able to diversify into new products and industries, while others continue to face challenges in diversification? This doctorate research explores the different pathways to diversification. It follows the three-stage modular structure of DBA for Cranfield School of Management. This thesis consists of a systematic literature review, a single qualitative case study on UAE, and a research synthesis of published cases on Singapore, Norway and UAE. The linking document provides a summary of the three projects a
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Dhillon, Ravinder. "Diagnostic imaging pathways /." Connect to this title, 2006. http://theses.library.uwa.edu.au/adt-WU2007.0126.

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Barrett, Susan. "Pathways to Detention." Thesis, Griffith University, 2007. http://hdl.handle.net/10072/366448.

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This research utilised a range of deterministic and stochastic analyses to establish whether Queensland's juvenile justice system processes Aboriginal and non-Aboriginal young male offenders differently. The impetus for this research stemmed from the continued high rates of Aboriginal over-representation within Australia's criminal justice system, despite diversionary measures to reduce such over-representation, and a commitment by the Queensland Government to reduce by 50% the number of Aboriginal peoples in custody by the year 2011. There are two competing hypotheses concerning the cause of
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Books on the topic "Pathways"

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Dallas, Donald. Pathways. Longman, 1986.

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Dallas, Donald. Pathways. Longman, 1986.

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Rilke, Rainer Maria. Pathways. [Aralia Press], 2010.

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Nannini, Gregg M. Pathways. Plowman, 1994.

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Bergren, Lisa Tawn. Pathways. WaterBrook Press, 2001.

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Asomugha, Chibuzo. Pathways. Pan-Afric Publishers, 1995.

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McGrady, Angele, and Donald Moss. Pathways to Illness, Pathways to Health. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1379-1.

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H, Nodar Richard, and Musiek Frank E, eds. Efferent auditory system: Structure and function. Singular Publishing Group, 1997.

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Development, Canada Human Resources. Career pathways. Human Resources Development Canada, 1996.

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Dekker, Henk-Jan. Cycling Pathways. Amsterdam University Press, 2021. http://dx.doi.org/10.5117/9789463728478.

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In an effort to fight climate change, many cities try to boost their cycling levels. They often look towards the Dutch for guidance. However, historians have only begun to uncover how and why the Netherlands became the premier cycling country of the world. Why were Dutch cyclists so successful in their fight for a place on the road? Cycling Pathways: The Politics and Governance of Dutch Cycling Infrastructure, 1920-2020 explores the long political struggle that culminated in today’s high cycling levels. Delving into the archives, it uncovers the important role of social movements and shows in
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Book chapters on the topic "Pathways"

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Tanggaard, Lene. "Pathways." In Creativity — A New Vocabulary. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-41907-2_14.

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Guzzanti, Paula, and John D'Arcy. "Pathways." In The Different Faces of Politics in the Visual and Performative Arts. Routledge India, 2023. http://dx.doi.org/10.4324/9781032640464-16.

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Davies, Robert W. "Pathways." In The Era of Global Transition. Palgrave Macmillan UK, 2012. http://dx.doi.org/10.1057/9781137283481_6.

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Tanggaard, Lene. "Pathways." In Creativity — A New Vocabulary. Palgrave Macmillan UK, 2016. http://dx.doi.org/10.1057/9781137511805_12.

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Rosetti, Dewey. "Pathways." In Parenting Bright Kids Who Struggle in School. Routledge, 2021. http://dx.doi.org/10.4324/9781003236993-12.

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Anwaruzzaman, A. K. M. "Pathways." In Migration Studies. Routledge, 2025. https://doi.org/10.4324/9781003586791-10.

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Stoorvogel, Willem, Hans J. Geuze, and Ger J. Strous. "Endocytic Pathways." In Endocytosis. Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-84295-5_21.

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Mendoza, John E. "Association Pathways." In Encyclopedia of Clinical Neuropsychology. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-57111-9_679.

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Mendoza, John E. "Projection Pathways." In Encyclopedia of Clinical Neuropsychology. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-57111-9_688.

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Crosnoe, Robert, and Aprile D. Benner. "Educational Pathways." In Handbooks of Sociology and Social Research. Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-20880-0_8.

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Conference papers on the topic "Pathways"

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Otte, Lennart B., Christer Hogstrand, Adil Mardinoglu, and Miao Guo. "Multi-Omics biological embeddings for ML-models." In The 35th European Symposium on Computer Aided Process Engineering. PSE Press, 2025. https://doi.org/10.69997/sct.136974.

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Machine learning algorithms have led to the development of numerous vector embeddings for biological entities such as metabolites, proteins, genes, and enzymes. However, these embeddings often lack contextual information due to their specialized focus on individual omics. Disease progression and biosynthesis pathways are increasingly understood through complex, multi-layered networks that integrate diverse omics data and intricate signaling and reaction sequences. Capturing these relationships in a meaningful way requires embeddings that account for both functional and multi-modal dependencies
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Hariri, Mohiedin Bagheri, Bruce Brown, and Srdjan Nesic. "Revisiting the Anodic Dissolution of Pure Iron in Strong Acids." In CONFERENCE 2022. AMPP, 2022. https://doi.org/10.5006/c2022-17681.

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Abstract The goal of the research reported herein was to accomplish a quantitative mechanistic analysis of iron dissolution in strong acid in a potential range in the proximity of its open circuit potential (OCP), leading to articulation of a revised narrative of BDD† mechanism for iron dissolution; additional mechanistic pathways were postulated in addition to the hypothesized mechanisms of BDD and Heusler. Thirty-eight different pathways were investigated here and theoretical Butler-Volmer equations were written for each. The kinetic consequences of each pathway and the corresponding theoret
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Park, Minseong, Hegwon Chung, and Jiyong Kim. "Comparative Techno-economic Assessment of Hydrogen Production, Storage and Refueling Pathways." In Foundations of Computer-Aided Process Design. PSE Press, 2024. http://dx.doi.org/10.69997/sct.119682.

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Hydrogen, as a clean and versatile energy carrier, holds immense promise for addressing the world�s growing energy and environmental challenges. However, hydrogen-based energy systems face challenges related to efficient storage methods, energy-intensive production, refueling processes, and overall cost-effectiveness. To solve this problem, a superstructure was developed that integrates overall technologies related to hydrogen energy transportation. This study synthesizes process pathways for hydrogen energy transportation method including energy carrier production, storage, and refueling, bas
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Tunçer, Bige, Zdravko Trivic, Rudi Stouffs, et al. "Informed Design of Pedestrian Pathways." In CAADRIA 2024: Accelerated Design. CAADRIA, 2024. http://dx.doi.org/10.52842/conf.caadria.2024.2.405.

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Inoue, Katsumi, Andrei Doncescu, Gabriel Synaeve, and Nabil Kabbak. "Main Pathway Discovery in Metabolic Pathways." In 2010 IEEE 24th International Conference on Advanced Information Networking and Applications Workshops. IEEE, 2010. http://dx.doi.org/10.1109/waina.2010.88.

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Buck, Steven L., and Roger Knight. "Model of dual rod pathways." In OSA Annual Meeting. Optica Publishing Group, 1989. http://dx.doi.org/10.1364/oam.1989.fk2.

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We offer a model of dual rod pathways that incorporate recent psychophysical, physiological, and anatomical work. Flicker sensitivity studies suggest that one rod pathway, π0, has greater absolute sensitivity but poorer high temporal frequency responses than the other pathway, π0 (Conner, 1982; Connor and MacLeod, 1977; Sharpe, Stockman, and MacLeod, in press). The dual pathways may arise from differential electrical coupling of rods and cones via gap junctions as a function of adaptation level (Yang and Wu, 1989), so that π0 signals travel through rod pathways and π0 signals travel through co
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Zhang, Ayla, and Jake Y. Chen. "Evaluating Cancer Drug-Targeting Pathways with Large Language Models." In 9th International Conference on Artificial Intelligence, Soft Computing And Applications. Academy & Industry Research Collaboration, 2025. https://doi.org/10.5121/csit.2025.150405.

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Integrating artificial intelligence into drug discovery holds great potential for prioritizing therapeutic targets. This study presents a novel framework combining bioinformatics tools and AI-driven evaluations to streamline target identification. Using pancreatic adenocarcinoma (PAAD) as a case study, we analyzed 252 candidate genes and associated pathways derived from the PAGER database. ChatGPT-4o evaluated pathways by scoring them across seven categories using structured prompts and weighted criteria to ensure robustness. Our approach demonstrated a statistically significant differentiatio
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Wu, Andy, Jung-Bin Yim, Eric Caspary, Ali Mazalek, Sanjay Chandrasekharan, and Nancy J. Nersessian. "Kinesthetic pathways." In the 8th ACM conference. ACM Press, 2011. http://dx.doi.org/10.1145/2069618.2069624.

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Bekaert, Jeroen, Xiaoming Liu, Herbert Van de Sompel, Carl Lagoze, Sandy Payette, and Simeon Warner. "Pathways core." In the 6th ACM/IEEE-CS joint conference. ACM Press, 2006. http://dx.doi.org/10.1145/1141753.1141863.

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Mehta, Meghna, Ahmed Sabbir Arif, Apurva Gupta, et al. "Active Pathways." In ISS '16: 2016 ACM International Conference on Interactive Surfaces and Spaces. ACM, 2016. http://dx.doi.org/10.1145/2992154.2992176.

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Reports on the topic "Pathways"

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Wright, Adam, Marija Milacic, Karen Rothfels, et al. Evaluating the Predictive Accuracy of Reactome's Curated Biological Pathways. Reactome, 2022. http://dx.doi.org/10.3180/poster/20221109wright.

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Reactome is a database of human biological pathways manually curated from the primary literature and peer-reviewed by experts. To evaluate the utility of Reactome pathways for predicting functional consequences of genetic perturbations, we compared predictions of perturbation effects based on Reactome pathways against published empirical observations. Ten cancer-relevant Reactome pathways, representing diverse biological processes such as signal transduction, cell division, DNA repair, and transcriptional regulation, were selected for testing. For each pathway, root input nodes and key pathway
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Skone, Timothy J. CTL Diesel, Pathways. Office of Scientific and Technical Information (OSTI), 2013. http://dx.doi.org/10.2172/1509367.

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Barter, Garrett, David Reichmuth, Jessica Westbrook, et al. Transportation Energy Pathways LDRD. Office of Scientific and Technical Information (OSTI), 2012. http://dx.doi.org/10.2172/1117264.

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Landrum, Mary Beth, Kate Stewart, and David Cutler. Clinical Pathways to Disability. National Bureau of Economic Research, 2007. http://dx.doi.org/10.3386/w13304.

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Cheng, Chingwen, and Ramandeep Kaur. El Paso Pedestrian Pathways. Landscape Architecture Foundation, 2022. http://dx.doi.org/10.31353/cs1880.

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Reynolds, Anthony, Xiao Li, MD Reza E Rabby, Mageshwari Komarasamy, and Glenn Grant. Discovering SPP Thermomechanical Pathways. Office of Scientific and Technical Information (OSTI), 2021. http://dx.doi.org/10.2172/1984871.

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Staie, Brittany, and Brian Mirletz. Session 3: Agrivoltaics Pathways. Office of Scientific and Technical Information (OSTI), 2024. http://dx.doi.org/10.2172/2446837.

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Novy, Andreas, Gustav Resch, and Nathalie Spittler. Chapter 8. Transformation pathways. Verlag der Österreichischen Akademie der Wissenschaften, 2025. https://doi.org/10.1553/aar2-ch8.

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Matthews, Lisa, Guanming Wu, Robin Haw, et al. Illuminating Dark Proteins using Reactome Pathways. Reactome, 2022. http://dx.doi.org/10.3180/poster/20221027matthews.

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Diseases are often the consequence of proteins or protein complexes that are non-functional or that function improperly. An active area of research has focused on the identification of molecules that can interact with defective proteins and restore their function. While 22% percent of human proteins are estimated to be druggable, less than fifteen percent are targeted by FDA-approved drugs, and the vast majority of untargeted proteins are understudied or so-called "dark" proteins. Elucidation of the function of these dark proteins, particularly those in commonly drug-targeted protein families,
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Enright, Nicole, and Steve Nicholas. Solar Market Pathways Final Report. Office of Scientific and Technical Information (OSTI), 2018. http://dx.doi.org/10.2172/1474296.

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