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1

Farahnaz, Sadoughi Razieh Mirzaeian* Masoud Jafarpishe Parastoo Yarmohammadi. "ASSESSMENT OF THE USERS' PERSPECTIVES ON THE PERFORMANCE OF ELECTRONIC PATIENT'S DRUG CHART IN THE PHARMACY INFORMATION SYSTEM." Indo American Journal of Pharmaceutical Sciences 04, no. 06 (2017): 1587–92. https://doi.org/10.5281/zenodo.818146.

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Introduction:The targeted application of the technology for the record of the drug information may substantially assist the healthcare service providers supporting the drug-related decisions. This study intended to assess the performance of the electronic patient’s drug chart integrated in the pharmacy information system [PIS] by comparing the users’ viewpoints before and after its administration. Methods: This study was conducted using applied and descriptive-analytical research method in 2016. Research population consisted of the nursing staff, pharmacy technicians as well as pharmacists fro
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Hartzema, Abraham G., Miquel S. Porta, Hugh H. Tilson, et al. "Medication Usage Patterns in Patients with Human Immunodeficiency Virus Infection: A Comparison of Patient-Reported Medication Usage with Medical Chart Review." DICP 25, no. 12 (1991): 1374–78. http://dx.doi.org/10.1177/106002809102501217.

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Patients infected with the human immunodeficiency virus (HIV) receive numerous medications from multiple providers. As a result, it is important that medication usage is properly documented in each patient's medical record. Lack of adequate documentation may confound a provider's assessment of drug efficacy, potentially leading to an increased incidence of drug interactions and adverse effects. The objective of this study was to determine if discrepancies exist between patient-reported medication usage and that documented in the medical record by healthcare providers. Data were obtained using
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Birks, M. E., S. Aiono, T. R. Magee, and R. B. Galland. "A Simple Way to Improve DVT Protocol Compliance." Phlebology: The Journal of Venous Disease 16, no. 3 (2002): 121–24. http://dx.doi.org/10.1177/026835550201600308.

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Objective: To assess the impact on deep vein thrombosis (DVT) protocol violations of the introduction of a label attached to the patient's drug chart, which specifically allows low-dose subcutaneous heparin or thromboembolic deterrent stockings (TEDS) to be prescribed as appropriate. Design: An audit study. Setting: Department of General Surgery of a District General Hospital in the United Kingdom. Method: All adult general surgical inpatients on a Weekday were studied. Staff were not forewarned of the studies. Patient details and risk factors for DVT were noted. Details of administered DVT pr
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Lichtman, S. M., and M. K. Boparai. "Geriatric medication management: Evaluation of pharmacist interventions and potentially inappropriate medication (PIM) use in older (≥65 years) cancer patients." Journal of Clinical Oncology 27, no. 15_suppl (2009): 9507. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.9507.

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9507 Background: Polypharmacy and inappropriate drug use are risk factors for adverse drug reactions (ADR) and poor compliance in older cancer patients. Drug evaluations in the past have not focused on this group. An evaluation of the prevalence of PIMs, pharmacist interventions, and the number and type of medications was performed. An educational component helped patients with drug management to increase adherence, avoid drug-drug and drug-disease interactions. Methods: A geriatric clinical pharmacist reviewed patient's medications, assessed understanding of their drugs, evaluated adherence,
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McDonnell, Patrick J., and Michael R. Jacobs. "Hospital Admissions Resulting from Preventable Adverse Drug Reactions." Annals of Pharmacotherapy 36, no. 9 (2002): 1331–36. http://dx.doi.org/10.1345/aph.1a333.

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BACKGROUND: Adverse drug reactions (ADRs) are a significant cause of hospital admissions. These events can lead to significant morbidity and mortality and financial costs. ADRs that may be preventable might be considered a form of medication error. OBJECTIVE: To assess the potential preventability of ADRs directly related to a patient's hospital admission. METHODS: A retrospective chart review of 437 ADRs occurring during an 11-month period was conducted at a university hospital. A subset of these events leading to hospital admissions was identified for further review. Those that resulted in a
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Drucker, Aaron M., Elena Pope, Sanjay Mahant, and Miriam Weinstein. "Vincristine and Corticosteroids as First-Line Treatment of Kasabach-Merritt Syndrome in Kaposiform Hemangioendothelioma." Journal of Cutaneous Medicine and Surgery 13, no. 3 (2009): 155–59. http://dx.doi.org/10.2310/7750.2008.08006.

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Background: Historically, patients with the consumptive coagulopathy Kasabach-Merritt syndrome (KMS) have been treated with systemic corticosteroids as first-line therapy, but many patients do not respond. Recently, there have been increasing reports of the use of the chemotherapeutic drug vincristine in these patients. Objective: To report a case of a newborn with a kaposiform hemangioendothelioma (KHE) of the right leg associated with KMS treated successfully with vincristine and oral corticosteroids. Methods: The patient's chart and the literature on the subject were reviewed using Medline
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Hamilton, Robert A., and Tammy Gordon. "Incidence and Cost of Hospital Admissions Secondary to Drug Interactions Involving Theophylline." Annals of Pharmacotherapy 26, no. 12 (1992): 1507–11. http://dx.doi.org/10.1177/106002809202601202.

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OBJECTIVE: To determine the incidence and cost of hospital admissions for theophylline toxicity, which occurred as a result of the concurrent use of one of the following medications: cimetidine, erythromycin, or ciprofloxacin. DESIGN: Retrospective chart review (18 months, between June 1989 and November 1990). SETTING: A Department of Veterans Affairs Medical Center. PARTICIPANTS: All patients who were receiving theophylline chronically (913 patients) and also had a prescription for cimetidine (124 patients with 140 treatment courses), erythromycin (66 patients with 93 treatment courses), or c
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Nguyen, Patrick Viet-Quoc, Lucie Pelletier, Isabelle Payot, and Judith Latour. "The Delirium Drug Scale is associated to delirium incidence in the emergency department." International Psychogeriatrics 30, no. 4 (2017): 503–10. http://dx.doi.org/10.1017/s1041610217002538.

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ABSTRACTBackground:The Delirium Drug Scale (DDS) is an evaluation scale developed to assess a patient's drug burden for delirium. The primary goal is to validate the association between the DDS score and the incidence of delirium.Methods:This study was an observational retrospective cross-sectional chart review study in patients aged 75 years and older. It was carried out in three emergency departments of a tertiary care university health center. Patients were included if a medication list was available. Delirium present upon admission was assessed during the first five days of admission.Resul
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Clark, Sarah L., Megan R. Leloux, Ross A. Dierkhising, Gregory D. Cascino, and Sara E. Hocker. "IV fosphenytoin in obese patients." Neurology: Clinical Practice 7, no. 1 (2016): 45–52. http://dx.doi.org/10.1212/cpj.0000000000000322.

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AbstractBackground:Previous studies evaluated the disposition of IV phenytoin loading doses and found that obese patients had increased drug distribution into excess body weight, larger volumes of distribution, and longer half-lives when compared to their nonobese counterparts. We assess the safety and efficacy of fosphenytoin loading doses in patients with different body mass indices (BMIs).Methods:A retrospective chart review was conducted in 410 patients who received fosphenytoin. Patients were divided into 2 groups: BMI <30 (nonobese) and BMI ≥30 (obese). Patient demographics, fosphenyt
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Ratnapala, Udana Subodhika, Hiranya Wijesekara, Anuradha Illanganthilaka, et al. "Medication transcription errors at a tertiary healthcare facility in Uva province, Sri Lanka: A retrospective study." Ceylon Medical Journal 67, no. 4 (2022): 184–88. http://dx.doi.org/10.4038/cmj.v67i4.9748.

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Introduction: Medication transcription is an error-prone process in healthcare settings with paper-based documentation. However, it is often preventable. In Sri Lanka, a uniform medication chart is not currently in use.Objectives: To describe transcription errors with the aim of designing a standardized drug chart to minimize the transcription errors at a tertiary care facility in Uva province, Sri LankaMethods: This cross-sectional study was conducted in selected units at Provincial General Hospital, Badulla. All discharged patients after a minimum of 72 hours hospital stay were included. The
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Fleischhacker, W. "Treatment resistance in Schizophrenia." European Psychiatry 26, S2 (2011): 2023. http://dx.doi.org/10.1016/s0924-9338(11)73726-9.

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DiagnosisThe diagnosis of treatment resistant schizophrenia generally follows two not always consistent lines of thinking: one is based on research strategies, the other one on every day clinical practice. Both require a failure to respond to at least two (sometimes three) treatment attempts of adequate duration with an adequate dose of an antipsychotic.In research, one needs to define clearly operationalized criteria which can be applied and reproduced in different settings. Response data are usually operationalized using rating scales scores. Under routine treatment conditions physicians oft
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Fulmali, Amit, Sara Sheik, Amir-Humza Suleman, et al. "Time to Rectify the Neglect? Audit on Prescription Writing the Neglected skill. Audit Ref No: AU/006/01/2021." BJPsych Open 8, S1 (2022): S154. http://dx.doi.org/10.1192/bjo.2022.437.

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AimsPrescribing is a neglected skill amongst trainees. Prescription errors can harm patients. A recent Economic analysis published in BMJ Quality & Safety. Estimated that 237 million medication errors occur in England annually. Costing the NHS £98,462,582. Prescribing errors contributed to 21% of the total errors. It is important that all prescribers are aware of principles of safe prescribing. Our aim is to is to establish whether our practice is meeting standards of prescription writing in old age psychiatry ward setup.MethodsWe used prescription standards set by BMA, BNF and SABP (Surre
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Setyadi, Heribertus Ary, and Doddy Satrya Perbawa. "Sistem Informasi Rekam Medis Di Klinik Gigi Rumah Sakit Paru dr. Ario Wirawan Salatiga." Jurnal Infortech 3, no. 2 (2021): 110–16. http://dx.doi.org/10.31294/infortech.v3i2.11209.

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Abstrak - Saat ini pelayanan di klinik gigi Rumah Sakit Paru dr. Ario Wirawan (RSPAW) masih menggunakan cara konvensional atau offline. Proses pendaftaran pasien dapat dilakukan dengan datang ke klinik untuk mengambil nomor antrian. Untuk pasien baru wajib mengisi form pasien baru. Setelah itu pasien akan diperiksa oleh dokter, jika pasien yang sudah pernah periksa maka dokter akan melihat blangko yang berisi rekam medis pasien. Selesai proses pengerjaan dokter menulis terapi yang sudah diberikan di blangko rekam medis pasien. Tahap analisis yang dilakukan adalah menganalisis permasalahan sist
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Cohen, Kevin Bretonnel, Benjamin Glass, Hansel M. Greiner, et al. "Methodological Issues in Predicting Pediatric Epilepsy Surgery Candidates through Natural Language Processing and Machine Learning." Biomedical Informatics Insights 8 (January 2016): BII.S38308. http://dx.doi.org/10.4137/bii.s38308.

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Objective: We describe the development and evaluation of a system that uses machine learning and natural language processing techniques to identify potential candidates for surgical intervention for drug-resistant pediatric epilepsy. The data are comprised of free-text clinical notes extracted from the electronic health record (EHR). Both known clinical outcomes from the EHR and manual chart annotations provide gold standards for the patient's status. The following hypotheses are then tested: 1) machine learning methods can identify epilepsy surgery candidates as well as physicians do and 2) m
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Pammett, Robert T. "Evaluation of Prescription Adaptation Following Changes to A Provincial Drug Insurance Formulary." Pharmacy 7, no. 1 (2019): 6. http://dx.doi.org/10.3390/pharmacy7010006.

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On 1 December 2016, British Columbia’s (BC) provincial drug insurance program changed which medications in certain classes would benefit under the insurance program in an attempt to reduce expenditure. As part of the modernization, HMG-CoA reductase inhibitors (Statins), Angiotensin converting enzyme inhibitors (ACEI), angiotensin receptor blockers (ARB), and dihydropyridine calcium channel blockers (CCB) were affected. Prescribers and pharmacists had six months to discuss the changes with patients, and change medications if deemed necessary. Purpose: To quantify the changes made to prescripti
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Castilho, L., S. Nance, and J. R. Hamilton. "Investigation of anemia of unknown origin." Immunohematology 37, no. 3 (2021): 1–4. http://dx.doi.org/10.21307/immunohematology-2021-023.

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Abstract One of the most difficult concepts to explain when training immunohematology staff involves the investigation of hemolytic anemias. In the transfusion service and in the immunohematology reference laboratory setting, rapid and efficient investigation can be extremely important for patients with critical anemia requiring transfusion. The flow charts presented here provide possible patient scenarios and a logical sequence for initial and subsequent serologic testing for investigation. A clinical assessment of anemia of unknown origin or the finding of an unresolved positive antibody scr
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Martinez-Iglesias, Pedro Luis, Jaime Enrique Ruiz-Sternberg, Sebastian León-Leiva, et al. "Comorbidities among adults living with hiv from two healthcare centers in Colombia." Infectio 23, no. 1 (2018): 92. http://dx.doi.org/10.22354/in.v23i1.763.

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Objective: To determine the prevalence of comorbidities among adults living with HIV from two healthcare centers in Colombia, and to identify factors associated with comorbidity-free years.Methods: Observational, retrospective medical chart review study. Summary statistics for demographic and clinical characteristics were developed and relationship between comorbidity-free years were analyzed through Kaplan-Meier analysis and Cox regression.Results: 669 clinical charts were included, 71.7% were male and 16.1% were 50 years or older, 69.96% had at least one comorbidity. The most frequent comorb
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Kinard, Bryce W., Andrew S. Zale, and Kenneth L. Reed. "Efficacy of Midazolam/Meperidine vs Midazolam/Hydromorphone for Enteral Moderate Sedation in the Pediatric Dental Patient." Anesthesia Progress 71, no. 1 (2024): 15–18. http://dx.doi.org/10.2344/22-00037.

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Objective: The goal of this study was to compare the efficacy of midazolam/meperidine (M/M) vs midazolam/hydromorphone (M/H) for enteral moderate sedation along with inhalational sedation in pediatric dental patients. Methods: This retrospective chart review analyzed the charts of pediatric patients who received dental treatment under enteral moderate sedation with either M/M or M/H in combination with inhalational sedation (nitrous oxide/oxygen) at El Rio Community Health Centers (affiliated with NYU Langone) in Tucson, Arizona, from July 2014 to December 2020. Included subjects were between
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Fina, Paul M., Francesca E. Cunningham, Xinhua Zhao, et al. "Reporting of adverse drug events in the Veterans Health Administration for patients whose treatment with empagliflozin or apixaban was discontinued." American Journal of Health-System Pharmacy 77, no. 1 (2019): 22–32. http://dx.doi.org/10.1093/ajhp/zxz261.

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Abstract Purpose To examine the reporting rates of adverse drug events (ADEs) with apixaban and empagliflozin as reports move up to the next level of spontaneous reporting. Methods This was a retrospective cohort study of outpatients who discontinued apixaban or empagliflozin within 3 years of Food and Drug Administration (FDA) approval. We enriched the sample using an active surveillance strategy to identify subsets of patients with International Classification of Diseases (ICD) codes possibly associated with an ADE. Stratified random samples of charts were reviewed to determine if patients d
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Bandyopadhyay, Sanjib, Kaushik Mitra, Dipankar Bhaumik, and Saibal Das. "A STUDY ON POTENTIAL DRUG-DRUG INTERACTIONS AMONG PATIENTS ADMITTED UNDER DEPARTMENT OF MEDICINE IN A TERTIARY CARE HOSPITAL IN INDIA." Journal of Biomedical and Pharmaceutical Research 10, no. 1 (2021): 29–32. http://dx.doi.org/10.32553/jbpr.v10i1.829.

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Objective: This study was conducted to evaluate the potential drug-drug interactions (pDDIs) among patients admitted in a tertiary care hospital in India.
 Methods: This was anobservational and cross sectional study for 3 months. All the patients admitted in the general ward under Department of Medicine. Pre-structured proforma and patient’s charts were be used for data collection on the 2nd day of admission. For drug interactions, online ‘Medscape Drug Interaction Checker’ was used.
 Results: A total of 61 charts were screened. A total of 304 drugs with 57 different types were admit
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Murray, Diane, Cathy Sedgeworth, Moira Kinnear, and Lesley Diack. "EVALUATION OF AN ELECTRONIC PAEDIATRIC INTENSIVE CARE UNIT (PICU) MEDICATION RECONCILIATION (MR) FORM." Archives of Disease in Childhood 101, no. 9 (2016): e2.72-e2. http://dx.doi.org/10.1136/archdischild-2016-311535.74.

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AimTo gather opinions from doctors and pharmacists to improve the design of the PICU MR form generated by the electronic prescribing and clinical notes system to support transfer of care from PICU to downstream wards that use paper systems.MethodA purposive sample of 10 forms covering a comprehensive range of medication information common to PICU patients was selected from practice between March 2014 and May 2014. Pharmacists (n=7) and doctors (n=9) who received these forms on downstream wards were invited to participate in semi-structured one-to-one interviews (n=20) with the PICU pharmacist
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Staton, Nicola. "PRESCRIBING AND MONITORING OF GENTAMICIN IN NEONATES." Archives of Disease in Childhood 101, no. 9 (2016): e2.65-e2. http://dx.doi.org/10.1136/archdischild-2016-311535.68.

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AimTo evaluate the implementation of the National Institute for Health and Care Excellence (NICE) clinical guideline1 with regards to the prescribing, exposure and therapeutic drug level monitoring of gentamicin in early onset neonatal infection.MethodA selection of drug charts for babies who were prescribed gentamicin within 72 hrs of birth were reviewed. The number of doses of gentamicin administered, C-reactive protein (CRP) results, blood culture results and gentamicin trough levels were recorded. A new gentamicin prescription chart was developed based on the NICE clinical guideline1 and t
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Yismaw, Malede Berihun, Haileyesus Adam, and Ephrem Engidawork. "Identification and Resolution of Drug-Related Problems among Childhood Cancer Patients in Ethiopia." Journal of Oncology 2020 (March 16, 2020): 1–9. http://dx.doi.org/10.1155/2020/6785835.

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Background. Even though medications play a major role in the cure, palliation, and inhibition of disease, they also expose patients to drug-related problems. Drug-related problems are frequent and may result in reduced quality of life, morbidity, and mortality. Objectives. The study was aimed to identify, characterize, and resolve drug-related problems in the Pediatric Hematology/Oncology ward of Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods. A prospective observational study was conducted from 25 June to 25 October 2018 to assess DRPs on patients admitted at the pediatric
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Kobayashi, Takaaki, Brice Beck, Aaron C. Miller, Philip M. Polgreen, and Michael Ohl. "198. Chart Validation of an Algorithm for Identifying Patients with Intravenous Drug Use-Associated Endocarditis Using Administrative Code Data." Open Forum Infectious Diseases 6, Supplement_2 (2019): S118. http://dx.doi.org/10.1093/ofid/ofz360.273.

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Abstract Background Studies using administrative data have described increasing rates of intravenous drug use (IVDU)-associated infective endocarditis (IE) in the United States. These studies used International Classification of Disease (ICD) diagnosis codes to identify hospitalized patients with IE and any illicit drug use (i.e., opioid, amphetamine, cocaine or sedative), but were hindered by absence of specific ICD codes for IVDU. We reviewed charts to determine the positive predictive value (PPV) of ICD codes for identifying patients with IE and IVDU. Methods We examined national Veterans A
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Choudhury, Aklak, Gregor Young, Beshoy Reyad, Nirali Shah, and Radhea Rahman. "Can we improve the prescribing and delivery of oxygen on a respiratory ward in accordance with new British Thoracic Society oxygen guidelines?" BMJ Open Quality 7, no. 4 (2018): e000371. http://dx.doi.org/10.1136/bmjoq-2018-000371.

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The British Thoracic Society recommends oxygen delivery to achieve target oxygen saturation range between 94% and 98% for medically unwell adult patients, and 88% to 92% in patients at risk of hypercapnic respiratory failure. Interviews with our medical and nursing staff suggested that oxygen was sometimes being given to patients without a valid order and there was a failure to titrate oxygen to the stated oxygen saturation range. Our aim was to improve appropriate oxygen delivery to 90% of our patients on a 30-bedded respiratory ward within 3 months. We identified several key steps to safe ox
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Ntanganika, Esther, and Bhavee Patel. "P014 An audit assessing the prescribing of naloxone in paediatric patients." Archives of Disease in Childhood 104, no. 7 (2019): e2.17-e2. http://dx.doi.org/10.1136/archdischild-2019-nppc.24.

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AimTo assess whether paediatric patients who were prescribed opioids, had also been prescribed naloxone.MethodsThe audit was registered with the Clinical Audit and Effectiveness Department and ethical approval was not required. Patients who were taking weak opioids were excluded from this audit. A data collection sheet was created and data collected prospectively, over a two-month period. Forty-one inpatient medication charts were reviewed, to identify whether naloxone had been prescribed on the PRN section of the chart for patients who had been prescribed opioids, also to see whether the stan
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Alhaffar, Dana, Yan Han, Julianne Darling, Todd C. Skaar, Christopher A. Fausel, and Nasser H. Hanna. "Prevalence of the concurrent administration of contraindicated medications in patients with cancer treated with tyrosine kinase inhibitors (TKIs): A pilot study from the IU Simon Comprehensive Cancer Center." Journal of Clinical Oncology 39, no. 15_suppl (2021): e18714-e18714. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.e18714.

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e18714 Background: Polypharmacy may result in drug-drug interactions that reduce efficacy or increase toxicities to patients. Tyrosine kinase inhibitors (TKIs), which is standard therapy for many patients with cancer, have interactions with many commonly prescribed drugs (including proton pump inhibitors [PPIs] and cytochrome inhibitors/inducers) which alter their metabolism. Methods: Retrospective study of 100 consecutively chosen patients with advanced cancer treated with TKIs were identified. Patients < 18 years of age, participating in clinical trials, or taking an investigational treat
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Larkin, Trisha, Abdelrahman H. Elsayed, Roya Rafiee, et al. "Identification of Pharmacogenomic Single Nucleotide Polymorphism Variants As Contributors to Toxicity Phenotype in the Treatment of Acute Childhood Leukemia." Blood 136, Supplement 1 (2020): 25–26. http://dx.doi.org/10.1182/blood-2020-143195.

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Introduction: Despite more than 80% long-term survival in acute lymphoblastic leukemia (ALL), morbidity due to drug-related toxicities remains high. Treatment interruptions and omissions from these toxicities may affect survivorship outcomes and morbidities in pediatric cancer. Although multiple factors contribute to a patient's risk of toxicity pharmacogenetic factors have been shown to play critical roles. Genetic variation within genes involved in pharmacokinetic and pharmacodynamic pathways of chemotherapies can influence gene expression and/or activity resulting in inter-patient variation
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Collins, Kathryn, Julie A. Dopheide, Mengxi Wang, and Talene Keshishian. "Best practices for documentation of psychotropic drug-drug interactions in an adult psychiatric clinic." Mental Health Clinician 13, no. 1 (2023): 11–17. http://dx.doi.org/10.9740/mhc.2023.02.011.

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Abstract Introduction Psychotropic drug-drug interactions (DDIs) contribute to adverse drug events, but many go undetected or unmanaged. Thorough documentation of potential DDIs can improve patient safety. The primary objective of this study is to determine the quality of and factors associated with documentation of DDIs in an adult psychiatric clinic run by postgraduate year 3 psychiatry residents (PGY3s). Methods A list of high-alert psychotropic medications was identified by consulting primary literature on DDIs and clinic records. Charts of patients prescribed these medications by PGY3 res
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Bourke, Jill, Inger Bjeldbak‐Olesen, Per Mikael Nielsen, and Lars Kristian Munck. "Shared charts for prescription and administration: Increasing safety of drug treatment." International Journal of Risk & Safety in Medicine 15, no. 3-4 (2002): 183–91. https://doi.org/10.3233/jrs-2002-265.

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Introduction: Medication errors contribute up to 8% of all hospital admissions. Minimising the number of information transferrals and improving communication may increase the quality of drug treatment. Material and methods: The effect of introducing shared charts for prescription and administration on the quality of drug handling in a hospital was evaluated using chart review and observation of medicines administration. Results: Comparison of prescriptions in hospital records and nurse charts for medicines administration for 20 patients prior to introducing common charts revealed in no case co
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Zaffar, Sanna, and Penny Fletcher. "AN AUDIT OF THE PAEDIATRIC EMPIRIC ANTI-INFECTIVE GUIDELINES AND ANTI-INFECTIVE DRUG DOSE TABLE FOR CHILDREN." Archives of Disease in Childhood 101, no. 9 (2016): e2.7-e2. http://dx.doi.org/10.1136/archdischild-2016-311535.15.

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AimTo assess compliance with paediatric empiric anti-infective guidelines and anti-infective drug dose table for children.MethodData collection was carried out on the paediatric wards.Exclusions▸ Bone marrow transplant patients (BMT).▸ Patients not on empirical anti-infective treatmentData were collected prospectively between January and 30 February 2015. A data collection form was completed and data analysed using Excel.Standards(1) 90% adherence to the paediatric guidelines for empirical anti-infectives treatment(2) 90% prescriptions have the indication recorded in either the drug charts or
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Shaji, Bipin, Jereena George, Aishwarya Shrestha, Sharon Mary Stanly, and Noah M. Bose. "Prescription audit of antihypertensive drugs used in stroke patients in a tertiary care teaching hospital." International Journal of Basic & Clinical Pharmacology 11, no. 1 (2021): 41. http://dx.doi.org/10.18203/2319-2003.ijbcp20214887.

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Background: Stroke is considered as one of the important reasons of death and disability worldwide. A rational use of medications is needed to prevent the recurrence and the disease related complications.Methods: The current study is a prospective observational study. All stroke cases, with patients above the age of 25 and treated with antihypertensive agents were included in the study. A total of 189 patients were found suitable for inclusion in the study. Using a suitably designed data collection form, all pertinent data such as patient demographics, prescribed medicines, drug interactions a
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Fatin Fahad Aldenaini, Hakimah Khalil Almohander, Mariam Khalid Alsanad, et al. "Assessing ward system changes to mitigate medication administration errors: A comprehensive systematic review of interventional studies." World Journal of Biology Pharmacy and Health Sciences 15, no. 2 (2023): 270–78. http://dx.doi.org/10.30574/wjbphs.2023.15.2.0294.

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Background and aim: Medication administration errors are any deviation from the medication order specified by the prescriber on the patient's chart, specifically relating to the process of administering the medication to the patient. It is estimated that between 18.7% and 56% of all adverse events in hospitalised patients are attributable to preventable medication errors. The aim of this review was to assess the efficacy of nursing staff based ward system change interventions to reduce MAEs in in-patient settings. Methods: This review adhered to PRISMA guidelines and conducted an electronic se
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Farooq, M., C. Kirke, and K. Foley. "Documentation of drug allergy on drug chart in patients presenting for surgery." Irish Journal of Medical Science 177, no. 3 (2008): 243–45. http://dx.doi.org/10.1007/s11845-008-0166-7.

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Oborne, C. Alice, and Michal L. Luzac. "Over-the-Counter Medicine Use Prior to and During Hospitalization." Annals of Pharmacotherapy 39, no. 2 (2005): 268–73. http://dx.doi.org/10.1345/aph.1d160.

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BACKGROUND: In the UK, medicines are being reclassified from prescription-only drugs to allow supply without prescription. This allows faster and easier access to medicines to treat minor ailments and allows patients to take greater responsibility for their health. However, over-the-counter (OTC) drugs may pose risks to patients; thus, it is important to understand patients' OTC medicine use. OBJECTIVE: To assess use of OTC drugs prior to and during hospital stay of inpatients of all ages and specialties. METHODS: Data were collected for 186 randomly selected patients. Patients were interviewe
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Anderson, Gail D., Yixin Lin, Nancy R. Temkin, James H. Fischer, and H. Richard Winn. "Incidence of Intravenous Site Reactions in Neurotrauma Patients Receiving Valproate or Phenytoin." Annals of Pharmacotherapy 34, no. 6 (2000): 697–702. http://dx.doi.org/10.1345/aph.19264.

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OBJECTIVE: To determine the incidence of intravenous site reactions to phenytoin and valproate in a large population of patients with neurotrauma. DESIGN: Retrospective chart review of two double-blind, randomized clinical trials evaluating the use of antiepileptic drugs to prevent posttraumatic seizures in patients with neurotrauma: phenytoin versus placebo (n = 390), and valproate versus phenytoin with placebo (n = 385). Information collected from the charts included the number, type, and location of intravenous lines and intravenous site events. SETTING: Tertiary care trauma and university
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Chotanaphuti, Thanainit, Viroj Kawinwonggowit, Chumroonkiat Leelasestaporn, and Sombat Rojviroj. "A REAL WORLD MANAGEMENT OF OSTEOARTHRITIS (OA) KNEE PATIENTS WHO UNDERGO TOTAL KNEE REPLACEMENT – A RETROSPECTIVE STUDY IN THAILAND. (ARMOR STUDY)." Journal of Southeast Asian Medical Research 2, no. 1 (2018): 45–57. http://dx.doi.org/10.55374/jseamed.v2i1.23.

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Background: In Thailand. Total knee replacement (TKA) is a common clinical intervention to manage patients with OA (osteoarthritis). Public and private hospitals tend to exhibit different patients of TKA use. Hence, knowledge with regard to TKA practice patterns, use and treatment outcomes in different hospitals in Thailand will improve the understanding of clinical management of OA and patient care. Objectives: The primary objective of the study was to examine the patterns of pain management during pre-operative, hospital admission for TKA, and postoperative periods (surgery to 3 months after
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Shehab, M., F. Alrashed, and A. Alfadhli. "P811 Age as a Predictor of Serum Tumor Necrosis Factor Antagonist Drug and Anti-drug Antibody Concentrations in Inflammatory Bowel Disease; A Nationwide Retrospective Study." Journal of Crohn's and Colitis 18, Supplement_1 (2024): i1509. http://dx.doi.org/10.1093/ecco-jcc/jjad212.0941.

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Abstract Background Tumor necrosis factor antagonists (anti-TNFs) are effective for the induction and maintenance of remission in inflammatory bowel disease (IBD). Several factors have been shown to be associated with anti-TNF treatment failure. We aim to investigate the relationship between age and serum anti TNF drug and Anti-drug Antibody Concentrations Methods This was a multicenter retrospective cohort study. Chart review was conducted by evaluating patients' charts from July 2018 until September 2023. The impact pf age on anti-drug antibodies and serum drug concentration in patients with
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Demarco, Camille E., Pei Lu, David F. Peace, et al. "Characteristics, Social Factors, and Trends in HIV and AIDS-Related Lymphoma: A 23-Year Analysis Since the Implementation of c ART, a County Hospital AIDS Malignancy Project (CHAMP) Study." Blood 132, Supplement 1 (2018): 2304. http://dx.doi.org/10.1182/blood-2018-99-117391.

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Abstract Introduction: Stroger Hospital (CCH) and the Ruth M. Rothstein CORE Center (CC) are the largest health providers for HIV+ patients (pts) in Chicago and one of the largest HIV clinics in the United States. CCH/CC treat approximately 5,000 HIV+ individuals per year and 40 newly diagnosed HIV-associated cancers annually. The CHAMP Study was originally a retrospective database from 1990 to 2010 of all clinical, demographic, cancer characteristics of pts diagnosed with HIV/AIDS. Since then, the study has compiled data prospectively on all pts with hematological malignancies. In this study,
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IQBAL, SYED TALAT, and ZAINAB BATOOL. "CORTICOSTERIOD;." Professional Medical Journal 20, no. 05 (2013): 694–98. http://dx.doi.org/10.29309/tpmj/2013.20.05.1450.

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Introduction: Indoor patients in hospitals frequently use corticosteriods for different indications. As the number of drugs inprescriptions increases, the risk of drug-drug interactions increases. This study deals with the frequent use and drug-drug ofcorticosteriods. Objective: The present study was designed to determine the frequency of use of corticosteriods in indoor patients andthe resulting drug-drug interactions. Study design: 270 Prescriptions of indoor patients from different wards of Aziz Bhatti Shahidteaching hospital Gujrat were collected randomly over the period of three months. T
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Nelson, Kent M., and Robert L. Talbert. "Drug‐Related Hospital Admissions." Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 16, no. 4 (1996): 701–7. http://dx.doi.org/10.1002/j.1875-9114.1996.tb03658.x.

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To describe the frequency and pattern of drug‐related morbidity that results in hospital admission and the extent to which these admissions are avoidable, we prospectively reviewed the charts of 452 consecutive patients admitted to the intensive care unit or internal medicine service of a university‐affiliated, county hospital. Of these, 73 (16.2%) were admitted due to drug‐related morbidity Forty patients (54.8%) experienced drug therapy failure, 24 (32.9%) had an adverse reaction, and 9 (12.3%) had overdoses. Thirty‐six (49.3%) of these admissions were definitely avoidable. Compared with pat
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Ayalew, Mohammed Biset, and Esileman Abdela Muche. "Patient reported adverse events among epileptic patients taking antiepileptic drugs." SAGE Open Medicine 6 (January 1, 2018): 205031211877247. http://dx.doi.org/10.1177/2050312118772471.

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Objective: The aim of this study was to assess patient reported adverse events and associated factors among epileptic patients taking antiepileptic drugs on follow-up at University of Gondar Referral Hospital. Methods: Cross-sectional study was done on 354 adult epileptic patients. Patients who were on antiepileptic drugs for epilepsy treatment for less than a year, those who were below 18 years old, patients with incomplete information on the chart and those who were involuntary or uncooperative were excluded from the study. Data were entered in to SPSS version 20.0 for analysis. Bivariate an
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Yusuf, Asif, and Choudhury Camrul. "P24 Developing a paediatric electronic prescribing system." Archives of Disease in Childhood 103, no. 2 (2018): e1.29-e1. http://dx.doi.org/10.1136/archdischild-2017-314584.35.

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AimTo develop an electronic prescribing system (EPS), in a tertiary care paediatric hospital.MethodOne of the many benefits of electronic prescribing (EP) in secondary care, is the reduction in prescribing error rates.1 However, implementing EP in paediatrics, presents many challenges such as the increased complexity of medication dosing2 and varying doses of drugs depending on indication.2 An EPS was acquired from a local adult secondary care hospital and developed to include a specialist paediatric drug library with clinical decision support. The pharmacy department used a dispensing patient
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Alsharef, Zeineb, and Ahmed Abired. "Evaluation of Intravenous Drug Incompatibilities in the Intensive Care Units of Mitiga Military Hospital and Tripoli University Hospital, Tripoli, Libya." Libyan Journal of Medical Research 17, no. 2 (2023): 1–7. http://dx.doi.org/10.54361/ljmr.v17i2.01.

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This study aimed to evaluate intravenous (IV) drug incompatibilities in the Intensive Care Units (ICUs) of Mitiga Military Hospital (MMH) and Tripoli University Hospital (TUH). It sought to gather data on the compatibility of the most commonly used drugs when infused through the same line. Additionally, it attempted to generate a compatibility drug chart with reliable and updated information to improve safety in the administration of drugs to critically-ill patients. This was a retrospective clinical study. Data were obtained from 200 prescriptions in the MICUs of MMH and TUH. The study focuse
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Carter, Benjamin, and Rosie Ives. "P9 Paediatric prescribing: boosting the basics to reduce errors." Archives of Disease in Childhood 103, no. 2 (2018): e2.10-e2. http://dx.doi.org/10.1136/archdischild-2017-314585.18.

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AimsTo monitor the adherence to defined quality standard of prescribing in paediatric practice within Western Sussex Hospitals NHS Foundation Trust (WSHT). By identifying deficient areas, teaching and training can then be tailored to improve performance and safety.MethodA prospective audit of paediatric drug charts was performed at both WSHT sites (St Richards and Worthing General Hospitals) once weekly over a one month period. Drug charts were excluded only if no medications were yet prescribed. 22 patients audited from St Richard’s (SRH) and 34 from Worthing (WGH) were audited. Doctors withi
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IQBAL, SYED TALAT, ZAINAB BATOOL, and SAJID MEHMOOD. "POSSIBLE TOXIC EFFECTS OF BENZODIAZEPINES;." Professional Medical Journal 20, no. 02 (2013): 284–89. http://dx.doi.org/10.29309/tpmj/2013.20.02.654.

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Introduction: Benzodiazepines and its derivatives are used widely as anxiolytics, hypnotics, seizure control and as musclerelaxants. Design: The prescriptions of 270 patients were evaluated for moderate to severe drug interactions using drug interactiondetection software. Setting: Teaching hospital in Gujrat, Pakistan. Objective: This study is used to evaluate the possible toxic effects ofbenzodiazepine related drug-drug interactions in prescriptions of indoor patients. Material & Methods: The prescriptions wereprocessed through a software program named, The Medical Letter Adverse Drug Int
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Sadamoto, Kiyomi, Mikio Murata, Shinya Aoki, Takaharu Sadamoto, Hiromi Matayoshi, and Kiyoshi Kubota. "The idea of monitoring drug taking and life in the community." Journal of Scientific and Innovative Research 6, no. 3 (2017): 91–96. http://dx.doi.org/10.31254/jsir.2017.6301.

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Rationale, aims, and objectives: We have developed an innovative electronic device for supporting appropriate drug therapy and life. We used the device to monitor life and drug taking by elderly subjects including independent patients and patients who need home care services. The usefulness and usability of the device for monitoring life related subjects and adherence to drug therapy were evaluated. Methods: After obtaining informed consent for the study, we monitored 10 elderly subjects using the device for one month. After collecting the data, we analyzed personal daily life using both one-m
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Eken Sander, MD, Stephanie C., and Lon R. Hays, MD, MBA. "Prescription opioid dependence and treatment with methadone in pregnancy." Journal of Opioid Management 1, no. 2 (2005): 91. http://dx.doi.org/10.5055/jom.2005.0022.

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Prescription opioids are used medically to treat pain, but their diversion and abuse continues to escalate in the United States.1 Abuse of OxyContin (Purdue Pharma LP, Stamford, CT), a timed-release form of oxycodone, is a major focus of public health and law enforcement agencies. 2 The rise in opioid abuse may lead to an increase in opioid dependence in pregnancy, which was a focus of this study. Our retrospective chart review examined the demographics and patterns of opioid addiction of pregnant women admitted to an inpatient psychiatric unit in an academic medical center in central Kentucky
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Solomon, Jenna M., Veronica B. Ajewole, Amy M. Schneider, Manvi Sharma, and Eric H. Bernicker. "Evaluation of the prescribing patterns, adverse effects, and drug interactions of oral chemotherapy agents in an outpatient cancer center." Journal of Oncology Pharmacy Practice 25, no. 7 (2018): 1564–69. http://dx.doi.org/10.1177/1078155218798150.

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Purpose Although oral chemotherapy offers advantages over intravenous chemotherapy, it creates a unique set of challenges. Potential barriers include treatment complexity, patient responsibility for medication adherence and monitoring, reduced healthcare contact, and increased financial burden. The purpose of this study is to estimate the prevalence of drug-related problems among a sample of patients treated with oral chemotherapy agents. Methods A single-center, retrospective chart review was conducted on patients prescribed oral chemotherapy at our institution between 1 January 2017 and 31 A
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Rosenstein, Adam, Marcie Rabin, and Roger Kurlan. "Augmentation in Restless Legs Syndrome: Treatment with Gradual Medication Modification." Open Neurology Journal 9, no. 1 (2015): 4–6. http://dx.doi.org/10.2174/1874205x01509010004.

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Dopaminergic drugs can cause augmentation during the treatment of restless legs syndrome (RLS). We previously reported that sudden withdrawal of dopaminergic treatment was poorly tolerated. We now report our experience with gradual withdrawal of the dopaminergic drug during the drug substitution process using a retrospective chart review with comparison to previous data. Seven patients with RLS and dopaminergic drug-induced augmentation were treated with a gradual withdrawal of the offending drug and replacement with an alternative medication. Compared to sudden withdrawal, measured outcomes w
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