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Journal articles on the topic 'Patient self-Inflicted lung injury'

Author: Grafiati

Published: 21 September 2024

Last updated: 31 July 2025

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1

Carteaux, Guillaume, Mélodie Parfait, Margot Combet, Anne-Fleur Haudebourg, Samuel Tuffet, and Armand Mekontso Dessap. "Patient-Self Inflicted Lung Injury: A Practical Review." Journal of Clinical Medicine 10, no. 12 (2021): 2738. http://dx.doi.org/10.3390/jcm10122738.

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Patients with severe lung injury usually have a high respiratory drive, resulting in intense inspiratory effort that may even worsen lung damage by several mechanisms gathered under the name “patient-self inflicted lung injury” (P-SILI). Even though no clinical study has yet demonstrated that a ventilatory strategy to limit the risk of P-SILI can improve the outcome, the concept of P-SILI relies on sound physiological reasoning, an accumulation of clinical observations and some consistent experimental data. In this review, we detail the main pathophysiological mechanisms by which the patient’s

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Sun, Guinan, Jinjin Tian, Xueqin Zhang, and Dandan Li. "Advances in the Study of Patient Self-inflicted Lung Injury." International Journal of Biology and Life Sciences 7, no. 1 (2024): 11–15. http://dx.doi.org/10.54097/n26s9g12.

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Patient self-inflicted lung injury (P-SILI) is caused by excessive expansion of the lungs caused by excessive spontaneous breathing and the shear force caused by repeated alveolar atrophy and re-dilation in the gravity-dependent area. There are some benefits of keeping spontaneous breathing in patients with acute respiratory distress syndrome: 1. Reduce the need for sedation; 2. Exercise diaphragm function; 3. Improve the cardiopulmonary function of the patient. However, if the respiratory drive is too high, even with ventilator support, the patient will develop self-induced lung injury. In th

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3

Su, Po-Lan, Zhanqi Zhao, Yen-Fen Ko, Chang-Wen Chen, and Kuo-Sheng Cheng. "Spontaneous Breathing and Pendelluft in Patients with Acute Lung Injury: A Narrative Review." Journal of Clinical Medicine 11, no. 24 (2022): 7449. http://dx.doi.org/10.3390/jcm11247449.

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Acute respiratory distress syndrome (ARDS) is characterized by acute-onset rapid-deteriorating inflammatory lung injury. Although the preservation of spontaneous breathing may have physiological benefits in oxygenation, increasing evidence shows that vigorous spontaneous breathing may aggravate lung injury (i.e., patient self-inflicted lung injury). Increased lung stress and pendelluft, which is defined as intrapulmonary gas redistribution without a significant change in tidal volume, are important mechanisms of patient self-inflicted lung injury. The presence of pendelluft may be considered a

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4

Carteaux, G., F. Perier, T. Maraffi, K. Razazi, N. De Prost, and A. Mekontso Dessap. "Patient self-inflicted lung injury : ce que le réanimateur doit connaître." Médecine Intensive Réanimation 28, no. 1 (2019): 11–20. http://dx.doi.org/10.3166/rea-2019-0087.

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5

Deshwal, Himanshu, Ahmed Elkhapery, Rudra Ramanathan, et al. "Patient-Self Inflicted Lung Injury (P-SILI): An Insight into the Pathophysiology of Lung Injury and Management." Journal of Clinical Medicine 14, no. 5 (2025): 1632. https://doi.org/10.3390/jcm14051632.

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Acute respiratory distress syndrome (ARDS) is a heterogeneous group of disease entities that are associated with acute hypoxic respiratory failure and significant morbidity and mortality. With a better understanding and phenotyping of lung injury, novel pathophysiologic mechanisms demonstrate the impact of a patient’s excessive spontaneous breathing effort on perpetuating lung injury. Patient self-inflicted lung injury (P-SILI) is a recently identified phenomenon that delves into the impact of spontaneous breathing on respiratory mechanics in patients with lung injury. While the studies are hy

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Sklienka, Peter, Michal Frelich, and Filip Burša. "Patient Self-Inflicted Lung Injury—A Narrative Review of Pathophysiology, Early Recognition, and Management Options." Journal of Personalized Medicine 13, no. 4 (2023): 593. http://dx.doi.org/10.3390/jpm13040593.

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Patient self-inflicted lung injury (P-SILI) is a life-threatening condition arising from excessive respiratory effort and work of breathing in patients with lung injury. The pathophysiology of P-SILI involves factors related to the underlying lung pathology and vigorous respiratory effort. P-SILI might develop both during spontaneous breathing and mechanical ventilation with preserved spontaneous respiratory activity. In spontaneously breathing patients, clinical signs of increased work of breathing and scales developed for early detection of potentially harmful effort might help clinicians pr

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7

MacIntyre, Neil. "Managing mechanical ventilation: Clinical challenges 2024." Journal of Precision Respiratory Medicine 8, no. 1 (2025): 26–32. https://doi.org/10.2500/jprm.2025.8.240013.

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Positive pressure mechanical ventilation (PMV) has provided effective life support to millions of patients over the past century. PMV safety, however, has been an ongoing clinical challenge over this same time period. In this article, four “hot topics” with regard to PMV safety are discussed: ventilator-induced lung injury, air trapping, patient-ventilator asynchronies, and self-inflicted lung injury. Evidence-based approaches to recognition and management of these issues are presented and supplemented by novel thoughts from recent literature.

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8

Tobin, Martin J., Amal Jubran, and Franco Laghi. "Respiratory Drive Measurements Do Not Signify Conjectural Patient Self-inflicted Lung Injury." American Journal of Respiratory and Critical Care Medicine 203, no. 1 (2021): 142–43. http://dx.doi.org/10.1164/rccm.202009-3630le.

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9

Marongiu, Ines, Douglas Slobod, Marco Leali, Elena Spinelli, and Tommaso Mauri. "Clinical and Experimental Evidence for Patient Self-Inflicted Lung Injury (P-SILI) and Bedside Monitoring." Journal of Clinical Medicine 13, no. 14 (2024): 4018. http://dx.doi.org/10.3390/jcm13144018.

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Patient self-inflicted lung injury (P-SILI) is a major challenge for the ICU physician: although spontaneous breathing is associated with physiological benefits, in patients with acute respiratory distress syndrome (ARDS), the risk of uncontrolled inspiratory effort leading to additional injury needs to be assessed to avoid delayed intubation and increased mortality. In the present review, we analyze the available clinical and experimental evidence supporting the existence of lung injury caused by uncontrolled high inspiratory effort, we discuss the pathophysiological mechanisms by which incre

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10

Fang, Xiaorong, Changjiang Yu, and Fan He. "The Self-Inflicted Multiple Organs Injury with Nail Gun." Heart Surgery Forum 24, no. 6 (2021): E1049—E1051. http://dx.doi.org/10.1532/hsf.4201.

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We report the case of a patient with injuries to multiple organs as a result of attempted suicide with a nail gun. The patient shot 12 nails into his chest, causing damage to multiple organs, including the heart, lungs, and stomach. With timely emergency surgery, we successfully removed all the nails, and the patient was discharged from the hospital two weeks after surgery.

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11

Patel, Bhakti K., Krysta S. Wolfe, Jesse B. Hall, and John P. Kress. "A Word of Caution Regarding Patient Self-inflicted Lung Injury and Prophylactic Intubation." American Journal of Respiratory and Critical Care Medicine 196, no. 7 (2017): 936. http://dx.doi.org/10.1164/rccm.201702-0410le.

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12

Nguyen, Trinh, and Sumedh Hoskote. "PATIENT SELF-INFLICTED LUNG INJURY: THE CASE AGAINST EARLY SPONTANEOUS VENTILATION IN ARDS." Chest 156, no. 4 (2019): A1279. http://dx.doi.org/10.1016/j.chest.2019.08.1150.

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13

Yoshida, Takeshi, Domenico L. Grieco, Laurent Brochard, and Yuji Fujino. "Patient self-inflicted lung injury and positive end-expiratory pressure for safe spontaneous breathing." Current Opinion in Critical Care 26, no. 1 (2020): 59–65. http://dx.doi.org/10.1097/mcc.0000000000000691.

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14

Moellhoff, Nicholas, Philipp Groene, Ludwig Ney, and Daniela Hauer. "Entwicklung einer Riesenbulla unter Spontanatmung durch „patient self-inflicted lung injury“ bei COVID-19-Pneumonie." Der Anaesthesist 71, no. 4 (2021): 303–6. http://dx.doi.org/10.1007/s00101-021-01072-w.

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ZusammenfassungSARS-CoV‑2 und die damit assoziierte COVID-19-Erkrankung stellen Gesundheitssysteme weltweit vor große Herausforderungen. Fast täglich werden neue Erkenntnisse zu Diagnostik, Klinik und Therapie der Erkrankung publiziert. Dieser Fallbericht beschreibt den letalen Krankheitsverlauf eines 81-jährigen Patienten ohne pulmonale Vorerkrankungen, der als Komplikation der COVID-19-Pneumonie unter nichtinvasiver High-Flow-Sauerstofftherapie eine Riesenbulla entwickelte. Pathophysiologisch kommen/kommt eine virusbedingte diffuse Zerstörung des Alveolargewebes und/oder die „patient self-in

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Battaglini, Denise, Chiara Robba, Lorenzo Ball, et al. "Noninvasive respiratory support and patient self-inflicted lung injury in COVID-19: a narrative review." British Journal of Anaesthesia 127, no. 3 (2021): 353–64. http://dx.doi.org/10.1016/j.bja.2021.05.024.

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16

Kouch, Michael, and Laura Evans. "Is Time-of-Flight Ready for Take Off to Measure Patient Self-Inflicted Lung Injury?*." Critical Care Medicine 50, no. 1 (2021): 168–70. http://dx.doi.org/10.1097/ccm.0000000000005237.

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17

Brochard, Laurent, Arthur S. Slutsky, and Antonio Pesenti. "Reply: “A Word of Caution Regarding Patient Self-inflicted Lung Injury and Prophylactic Intubation” and “Hyperventilation (Not Ventilator)-induced Lung Injury”." American Journal of Respiratory and Critical Care Medicine 196, no. 7 (2017): 937–38. http://dx.doi.org/10.1164/rccm.201704-0780le.

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18

RIZKALLAH ALVES, BEATRIZ, PATRICK L. GORDAN, KATELYN HORTON, ARIANE PAZ Y MINO, RICAURTE CRESPO TREVINO, and AHMAD MASHLAH. "SPONTANEOUS PNEUMOMEDIASTINUM IN A NON-MECHANICALLY VENTILATED PATIENT WITH PROLONGED COVID-19: PATIENT SELF-INFLICTED LUNG INJURY (P-SILI)?" CHEST 164, no. 4 (2023): A3487—A3488. http://dx.doi.org/10.1016/j.chest.2023.07.2267.

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19

Cutuli, Salvatore Lucio, Domenico Luca Grieco, Teresa Michi, et al. "Personalized Respiratory Support in ARDS: A Physiology-to-Bedside Review." Journal of Clinical Medicine 12, no. 13 (2023): 4176. http://dx.doi.org/10.3390/jcm12134176.

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Acute respiratory distress syndrome (ARDS) is a leading cause of disability and mortality worldwide, and while no specific etiologic interventions have been shown to improve outcomes, noninvasive and invasive respiratory support strategies are life-saving interventions that allow time for lung recovery. However, the inappropriate management of these strategies, which neglects the unique features of respiratory, lung, and chest wall mechanics may result in disease progression, such as patient self-inflicted lung injury during spontaneous breathing or by ventilator-induced lung injury during inv

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20

Gattinoni, Luciano, John J. Marini, and Luigi Camporota. "Reply to Tobin et al.: Respiratory Drive Measurements Do Not Signify Conjectural Patient Self-inflicted Lung Injury." American Journal of Respiratory and Critical Care Medicine 203, no. 1 (2021): 143–44. http://dx.doi.org/10.1164/rccm.202009-3692le.

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21

Tsolaki, Vasiliki, George E. Zakynthinos, Maria-Eirini Papadonta, et al. "Neuromuscular Blockade in the Pre- and COVID-19 ARDS Patients." Journal of Personalized Medicine 12, no. 9 (2022): 1538. http://dx.doi.org/10.3390/jpm12091538.

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Acute respiratory distress syndrome (ARDS) accounts for a quarter of mechanically ventilated patients, while during the pandemic, it overwhelmed the capacity of intensive care units (ICUs). Lung protective ventilation (low tidal volume, positive-end expiratory pressure titrated to lung mechanics and oxygenation, permissive hypercapnia) is a non-pharmacological approach that is the gold standard of management. Among the pharmacological treatments, the use of neuromuscular blocking agents (NMBAs), although extensively studied, has not yet been well clarified. The rationale is to minimize the ris

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22

Giustivi, Davide, Francesco Bottazzini, and Mirko Belliato. "Respiratory Monitoring at Bedside in COVID-19 Patients." Journal of Clinical Medicine 10, no. 21 (2021): 4943. http://dx.doi.org/10.3390/jcm10214943.

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The SARS-CoV-2 (COVID-19) pandemic has forced some reflections to be had surrounding the ventilatory support to be applied to certain types of patients. The model of two phenotypes, set out by Professor Gattinoni and colleagues, suggests that adequate monitoring of respiratory effort may play a key role in the treatment of respiratory failure due to COVID-19. An insufficient control of the patient’s respiratory efforts could lead to an aggravation of lung damage, mainly due to the possibility of generating Patient Self-Inflicted Lung Injury (PSILI) with a consequent aggravation of the patholog

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Cruces, Pablo, B. Erranz, A. Perez, et al. "OP031 Topic: AS15–Lung: Respiratory Support/Acute Respiratory Failure/Other: PROTECTIVE MECHANISMS OF CPAP ON LUNGS AND DIAPHRAGM IN EXPERIMENTAL PATIENT SELF-INFLICTED LUNG INJURY." Pediatric Critical Care Medicine 25, no. 11S (2024): e12-e12. http://dx.doi.org/10.1097/01.pcc.0001084576.33121.58.

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24

Kondili, Eumorfia, Demosthenes Makris, Dimitrios Georgopoulos, Nikoletta Rovina, Anastasia Kotanidou, and Antonia Koutsoukou. "COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning." Journal of Personalized Medicine 11, no. 11 (2021): 1109. http://dx.doi.org/10.3390/jpm11111109.

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The COVID-19 disease can cause hypoxemic respiratory failure due to ARDS, requiring invasive mechanical ventilation. Although early studies reported that COVID-19-associated ARDS has distinctive features from ARDS of other causes, recent observational studies have demonstrated that ARDS related to COVID-19 shares common clinical characteristics and respiratory system mechanics with ARDS of other origins. Therefore, mechanical ventilation in these patients should be based on strategies aiming to mitigate ventilator-induced lung injury. Assisted mechanical ventilation should be applied early in

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Battaglini, Denise, and Patricia R. M. Rocco. "Challenges in Transitioning from Controlled to Assisted Ventilation in Acute Respiratory Distress Syndrome (ARDS) Management." Journal of Clinical Medicine 13, no. 23 (2024): 7333. https://doi.org/10.3390/jcm13237333.

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Acute respiratory distress syndrome (ARDS) presents significant challenges in critical care, primarily due to its inflammatory nature, which leads to impaired gas exchange and respiratory mechanics. While mechanical ventilation (MV) is essential for patient support, the transition from controlled to assisted ventilation is complex and may be associated with intensive care unit-acquired weakness, ventilator-induced diaphragmatic dysfunction and patient self-inflicted lung injury. This paper explores the multifaceted challenges encountered during this transition, with a focus on respiratory effo

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Gattinoni, Luciano, Simone Gattarello, Irene Steinberg, et al. "COVID-19 pneumonia: pathophysiology and management." European Respiratory Review 30, no. 162 (2021): 210138. http://dx.doi.org/10.1183/16000617.0138-2021.

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Coronavirus disease 2019 (COVID-19) pneumonia is an evolving disease. We will focus on the development of its pathophysiologic characteristics over time, and how these time-related changes determine modifications in treatment. In the emergency department: the peculiar characteristic is the coexistence, in a significant fraction of patients, of severe hypoxaemia, near-normal lung computed tomography imaging, lung gas volume and respiratory mechanics. Despite high respiratory drive, dyspnoea and respiratory rate are often normal. The underlying mechanism is primarily altered lung perfusion. The

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STARKMAN, ADAM E., DENA H. TRAN, MARC KAI, and WILLIAM GRIER. "DON'T PSILI WITH COVID! A CASE OF COVID-19 RESPIRATORY FAILURE AND MYASTHENIA GRAVIS EXACERBATION RESULTING IN PATIENT SELF-INFLICTED LUNG INJURY." CHEST 164, no. 4 (2023): A2530. http://dx.doi.org/10.1016/j.chest.2023.07.1686.

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28

Mostafa, Maha, Mina Adolf Helmy, Lydia Magdy Milad, and Ahmed Hasanin. "Patient self-induced lung injury risk in severe COVID-19." Anaesthesia Critical Care & Pain Medicine 41, no. 2 (2022): 101018. http://dx.doi.org/10.1016/j.accpm.2021.101018.

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29

Takahashi, Kazuhiro, Hiroaki Toyama, Yutaka Ejima, et al. "Endotracheal tube, by the venturi effect, reduces the efficacy of increasing inlet pressure in improving pendelluft." PLOS ONE 18, no. 9 (2023): e0291319. http://dx.doi.org/10.1371/journal.pone.0291319.

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In mechanically ventilated severe acute respiratory distress syndrome patients, spontaneous inspiratory effort generates more negative pressure in the dorsal lung than in the ventral lung. The airflow caused by this pressure difference is called pendelluft, which is a possible mechanisms of patient self-inflicted lung injury. This study aimed to use computer simulation to understand how the endotracheal tube and insufficient ventilatory support contribute to pendelluft. We established two models. In the invasive model, an endotracheal tube was connected to the tracheobronchial tree with 34 out

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Vesovic, Natasa, Aleksandar Ristanovic, Vlado Cvijanovic, et al. "Penetrating neck injury with consequential thoracic complications managed with use of video-assisted thoracoscopic surgery: A case report." Vojnosanitetski pregled 77, no. 3 (2020): 330–34. http://dx.doi.org/10.2298/vsp170904053v.

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Introduction. Penetrating injuries of the neck are potentially life-threatening conditions. They can cause injuries of larynx, trachea, esophagus and major blood vessels in this area. Case report. The patient was a 28-year-old male who was stabbed with broken glass penetrating the front side of the base of his neck. The patient had dyspnea and the wound was inflicted the night before admission to hospital. An otorhinolaryngologist found a stab wound in the region of the left basis of the neck. The wound was 2 cm long with no signs of bleeding and deep injuries of the anatomical structures of t

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31

Pérez Nieto, Orlando. "Lesión pulmonar autoinducida por el paciente (P-SILI)." Perspectiva de un residente de medicina crítica y medicina de urgencias. 2 (November 23, 2023): 1–8. http://dx.doi.org/10.58281/ccem23120701.

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The article reviews the scientific literature on Patient Self-Induced Lung Injury (P-SILI) in patients with Acute Respiratory Distress Syndrome (ARDS). It begins with a history since 1985, highlighting events of pulmonary edema related to hyperventilation in diabetic patients and advances in the understanding of pulmonary mechanics. Experimental studies in sheep and humans are detailed that show lung damage due to hyperventilation, highlighting the importance of spontaneous ventilation and alveolar damage. In addition, studies on alveolar hemorrhage post-intense exercise in animals and high-pe

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Okuda, Nao, Miyako Kyogoku, Yu Inata, et al. "Estimation of change in pleural pressure in assisted and unassisted spontaneous breathing pediatric patients using fluctuation of central venous pressure: A preliminary study." PLOS ONE 16, no. 3 (2021): e0247360. http://dx.doi.org/10.1371/journal.pone.0247360.

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Background It is important to evaluate the size of respiratory effort to prevent patient self-inflicted lung injury and ventilator-induced diaphragmatic dysfunction. Esophageal pressure (Pes) measurement is the gold standard for estimating respiratory effort, but it is complicated by technical issues. We previously reported that a change in pleural pressure (ΔPpl) could be estimated without measuring Pes using change in CVP (ΔCVP) that has been adjusted with a simple correction among mechanically ventilated, paralyzed pediatric patients. This study aimed to determine whether our method can be

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Pylypenko, M. M., and O. Yu Khomenko. "Modern strategies of adaptation to the respiratory support as a way to reduce self-induced lung injury (SILI)." Infusion & Chemotherapy, no. 3.2 (December 15, 2020): 243–44. http://dx.doi.org/10.32902/2663-0338-2020-3.2-243-244.

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Background. The success of respiratory support depends on the effectiveness of improving gas exchange, reducing lung damage, and adaptation of the respirator. Reduction of lung damage has previously been reported in the context of ventilator-associated injury: barotrauma in case of high plateau pressure and driving pressure, volume trauma in case of large tidal volume, atelectasis trauma due to the cyclic collapse of lungs on exhalation and opening on inspiration. Objective. To describe the features of lung damage during mechanical lung ventilation (MLV) and the possibility of its preven

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Koryakin, A. G., A. V. Vlasenko, E. P. Rodionov, and E. A. Evdokimov. "Asynchronies during respiratory support." Medical alphabet, no. 17 (September 8, 2022): 50–61. http://dx.doi.org/10.33667/2078-5631-2022-17-50-61.

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Asynchronies (desynchronies, dyssynchrony) is a disturbance of the harmonious interaction between the patient’s respiratory system and а ventilator. Asynchronies occur as a result of various reasons and with any form of respiratory support (non-invasive, assisted or fully controlled mechanical ventilation). Asynchrony is a significant cause of biomechanics and gas exchange disorders in the development of both self-injury and ventilator-induced lung injury, an increase of the respiratory support duration and mortality in patients with respiratory failure. Understanding the mechanisms of the asy

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Yamaguchi, Teppei, Junichi Shimizu, Yuko Oya, Yoshitsugu Horio, and Toyoaki Hida. "Drug-Induced Liver Injury in a Patient with Nonsmall Cell Lung Cancer after the Self-Administration of Fenbendazole Based on Social Media Information." Case Reports in Oncology 14, no. 2 (2021): 886–91. http://dx.doi.org/10.1159/000516276.

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Fenbendazole is a benzimidazole anthelmintic agent, with a broad antiparasitic range in animals such as dogs and pigs. The agent is also reported to exert antitumor effects and inhibit microtubule-associated tubulin polymerization, but its safety and tolerability profile in humans remains unclear. An 80-year-old female patient with advanced nonsmall cell lung cancer (NSCLC) was started on pembrolizumab monotherapy. The patient experienced severe liver injury 9 months later. An interview with her and her family revealed that she had been taking fenbendazole for a month, solely based on social m

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Matta, Simran. "Challenges and controversies in COVID-19 respiratory failure." Southwest Respiratory and Critical Care Chronicles 8, no. 35 (2020): 29–35. http://dx.doi.org/10.12746/swrccc.v8i35.743.

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COVID-19 pneumonia presents distinctive questions and challenges traditional conventions of management of respiratory failure. The trajectory of recommendations on customary intubation practices has undertaken significant paradigm shifts. This review will discuss the role of high flow nasal cannula oxygenation in mitigating respiratory distress in SARS-COV2 pneumonia and will explore the indices that can aid in the timely recognition of failure of non-invasive respiratory support modalities and escalation to mechanical ventilation. The work of breathing is a valuable yardstick for understandin

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Kuzkov, V. V., K. S. Lapin, E. V. Fot, and M. Yu Kirov. "Ventilator-associated lung injury in the intensive care unit and operating room – what's new?" Messenger of ANESTHESIOLOGY AND RESUSCITATION 17, no. 5 (2020): 47–61. http://dx.doi.org/10.21292/2078-5658-2020-17-5-47-61.

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The prophylaxis of ventilator-associated lung injury (VALI) and postoperative pulmonary complications (PPC) is of utmost importance to reduce complications both in the perioperative period of major surgery and in the intensive care unit (ICU).Protective approach to mechanical ventilation comprises a wide range of measures reducing the damage of the lung tissue associated with the stress and strain phenomena. The implementation of the strategy of high positive end-expiratory pressure (PEEP) in combination with alveolar recruitment maneuver has numerous limitations and requires further personali

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Al-Sadek, Tabet A., Desislav Niklev, Ahmed Al-Sadek, and Lina Al-Sadek. "Scapular Fractures in Blunt Chest Trauma – Self-Experience Study." Open Access Macedonian Journal of Medical Sciences 4, no. 4 (2016): 688–91. http://dx.doi.org/10.3889/oamjms.2016.135.

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AIM: The aim of this retrospective study was to report the scapular fractures in patients with blunt chest trauma and to present the type and the frequency of associated thoracic injuries.MATERIAL AND METHODS: Nine patients with fractures of the scapula were included in the study. The mechanisms of the injury, the type of scapular fractures and associated thoracic injuries were analysed.RESULTS: Scapular fractures were caused by high-energy blunt chest trauma. The body of the scapula was fractured in all scapular fractures. In all cases, scapular fractures were associated with other thoracic i

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Petitjeans, Fabrice, Sandrine Leroy, Cyrille Pichot, et al. "Improved understanding of the respiratory drive pathophysiology could lead to earlier spontaneous breathing in severe acute respiratory distress syndrome." European Journal of Anaesthesiology Intensive Care 2, no. 5 (2023): e0030. http://dx.doi.org/10.1097/ea9.0000000000000030.

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Optimisation of the respiratory drive, as early as possible in the setting of severe acute respiratory distress syndrome (ARDS) and not its suppression, could be a new paradigm in the management of severe forms of ARDS. Severe ARDS is characterised by tachypnoea and hyperpnoea, a consequence of a high respiratory drive. Some patients require endotracheal intubation, controlled mechanical ventilation (CMV) and paralysis to prevent overt ventilatory failure and self-inflicted lung injury. Nevertheless, intubation, CMV and paralysis do not address per se the high respiratory drive, they only supp

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María Tirado Patiño and Daniel Paz Martín. "¿Cuál es el volumen tidal ideal en pacientes ingresados en UCI sin SDRA que requieren ventilación mecánica más de 24 horas?" Revista Electrónica AnestesiaR 11, no. 8 (2019): 3. http://dx.doi.org/10.30445/rear.v11i8.768.

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La protección pulmonar en los pacientes críticos sometidos a ventilación mecánica, es uno de los objetivos que persiguen los facultativos cuando utilizan esta herramienta terapéutica; que, pese a todos sus beneficios y su uso extendido, no está exenta de efectos adversos. El apoyo ventilatorio en el Síndrome de Distrés Respiratorio Agudo (SDRA) consta de una serie de medidas, entre las que se incluye el volumen tidal (VT) bajo. Pero, ¿qué ocurre con aquellos pacientes que precisan más de 24 horas de ventilación mecánica sin criterios de SDRA? ¿Cuál es su VT recomendado? La evidencia científica

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Gulati, Uday, Christine Medeiros, Ananya Nanduri, et al. "Understanding Pneumomediastinum as a Complication in Patients With COVID-19: A Case Series." Journal of Investigative Medicine High Impact Case Reports 10 (January 2022): 232470962211271. http://dx.doi.org/10.1177/23247096221127117.

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Pneumomediastinum is a rare complication among non-coronavirus patients but has been published with increased incidence in patients positive for SARS-CoV-2 infection. Most of these studies report patients on mechanical ventilation and an understanding of mechanisms causing this remains limited. We aim to use an increasing occurrence in patients not on mechanical ventilation to further explore mechanisms that predispose patients to pneumomediastinum and to assess characteristics potentially related to poor outcomes. We report a case series of 37 patients diagnosed with COVID-19 and pneumomedias

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MCQUINN, MICHELLE W., LAURA L. KIMBERLY, BRENDAN PARENT, et al. "Self-Inflicted Gunshot Wound as a Consideration in the Patient Selection Process for Facial Transplantation." Cambridge Quarterly of Healthcare Ethics 28, no. 3 (2019): 450–62. http://dx.doi.org/10.1017/s0963180119000379.

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Abstract:Facial transplantation is emerging as a therapeutic option for self-inflicted gunshot wounds. The self-inflicted nature of this injury raises questions about the appropriate role of self-harm in determining patient eligibility. Potential candidates for facial transplantation undergo extensive psychosocial screening. The presence of a self-inflicted gunshot wound warrants special attention to ensure that a patient is prepared to undergo a demanding procedure that poses significant risk, as well as stringent lifelong management. Herein, we explore the ethics of considering mechanism of

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Neetz, Benjamin, Thomas Flohr, Felix J. F. Herth, and Michael M. Müller. "„Patient self-inflicted lung injury“ (P-SILI)." Medizinische Klinik - Intensivmedizin und Notfallmedizin, May 7, 2021. http://dx.doi.org/10.1007/s00063-021-00823-2.

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Arnal, Jean-Michel, and Robert Chatburn. "Paying attention to patient self-inflicted lung injury." Minerva Anestesiologica 85, no. 9 (2019). http://dx.doi.org/10.23736/s0375-9393.19.13778-9.

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Levis, Anja, Michael Gardill, Kaspar F. Bachmann, et al. "Bilateral phrenic nerve block to reduce hazardous respiratory drive in a mechanically ventilated patient with COVID‐19—A case report." Clinical Case Reports 12, no. 5 (2024). http://dx.doi.org/10.1002/ccr3.8850.

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Key Clinical MessageForced inspiration during mechanical ventilation risks self‐inflicted lung injury. However, controlling it with sedation or paralysis may cause polyneuropathy and myopathy. We tested bilateral phrenic nerve paralysis with local anesthetic in a patient, showing reduced inspiratory force. This offers an alternative to drug‐induced muscle paralysis.AbstractMechanical ventilation, although a life‐saving measure, can also pose a risk of causing lung injury known as “ventilator‐induced lung injury” or VILI. Patients undergoing mechanical ventilation sometimes exhibit heightened i

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Bachmann, María Consuelo, Pablo Cruces, Franco Díaz, et al. "Spontaneous breathing promotes lung injury in an experimental model of alveolar collapse." Scientific Reports 12, no. 1 (2022). http://dx.doi.org/10.1038/s41598-022-16446-2.

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AbstractVigorous spontaneous breathing has emerged as a promotor of lung damage in acute lung injury, an entity known as “patient self-inflicted lung injury”. Mechanical ventilation may prevent this second injury by decreasing intrathoracic pressure swings and improving regional air distribution. Therefore, we aimed to determine the effects of spontaneous breathing during the early stage of acute respiratory failure on lung injury and determine whether early and late controlled mechanical ventilation may avoid or revert these harmful effects. A model of partial surfactant depletion and lung co

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Tsolaki, Vasiliki, and George E. Zakynthinos. "Simulation to minimise patient self-inflicted lung injury: are we almost there?" British Journal of Anaesthesia, June 2022. http://dx.doi.org/10.1016/j.bja.2022.05.007.

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Pettenuzzo, Tommaso, Nicolò Sella, Francesco Zarantonello, et al. "How to recognize patients at risk of self-inflicted lung injury." Expert Review of Respiratory Medicine, September 28, 2022, 1–9. http://dx.doi.org/10.1080/17476348.2022.2128335.

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Cruces, Pablo, Benjamín Erranz, Carlos González, and Franco Diaz. "Morphological Differences Between Patient Self-inflicted and Ventilator-induced Lung Injury. An Experimental Study." American Journal of Respiratory and Critical Care Medicine, November 30, 2022. http://dx.doi.org/10.1164/rccm.202207-1360le.

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Pérez, Joaquin. "Patient Self-inflicted and Ventilator-induced Lung Injury: Two Sides of the Same Coin?" American Journal of Respiratory and Critical Care Medicine, March 23, 2023. http://dx.doi.org/10.1164/rccm.202302-0257le.

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