To see the other types of publications on this topic, follow the link: PBD.

Journal articles on the topic 'PBD'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'PBD.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Adedayo, Sosina. "Need Assessment of Farmers in Crop-Livestock Production Systems in Ido Local Government Area, Oyo State, Nigeria." International Journal of Agricultural Extension 7, no. 2 (2019): 177–86. http://dx.doi.org/10.33687/ijae.007.02.2730.

Full text
Abstract:
Agricultural projects and programmes funded by governments and donor agencies often failed to achieve the desired set objective(s) at the system levels. The study tries to assess the existing production practices with a view of coming up with a consensus farmer need in a crop-livestock production system at Ido Local Government Area (LGA). The study used a three-stage-sampling technique to elicit information from 225 respondents. Ido Local Government Area was purposively selected for the study. Three cells were randomly selected for the research, three villages were randomly selected in each ce
APA, Harvard, Vancouver, ISO, and other styles
2

Mendoza-Wilson, Ana María, and René Renato Balandrán-Quintana. "Effect of Constituent Units, Type of Interflavan Bond, and Conformation on the Antioxidant Properties of Procyanidin Dimers: A Computational Outlook." Journal of Chemistry 2017 (2017): 1–11. http://dx.doi.org/10.1155/2017/3535148.

Full text
Abstract:
Procyanidin (PC) dimers are powerful antioxidants, abundant in plant tissues, and also bioavailable. However, the role of the molecular structure of PCs on their antioxidant properties is still a controversial and not fully understood issue that needs to be addressed in a more specific way. The objective of this study was to analyze the effect of the constituent units, type of interflavan bond, and conformation on the antioxidant properties of PC dimers including PB3, PB4, PB5, PB6, PB7, and PB8, using the density functional theory (DFT) computational method. The analysis was performed in func
APA, Harvard, Vancouver, ISO, and other styles
3

Lin, Peter H., Debra Leslie, Mary Levine, Garth Davis, and Caldwell Esselstyn. "Plant-Based Diet Reverses Vascular Endothelial Dysfunction in Patients with Peripheral Arterial Disease." International Journal of Disease Reversal and Prevention 2, no. 1 (2020): 15. http://dx.doi.org/10.22230/ijdrp.2020v2n1a53.

Full text
Abstract:
OBJECtIVE: Peripheral arterial disease (PAD) is characterized by impaired arterial circulation to the extremities caused in part by atherosclerosis. This study examined the effect of a plant-based diet (PBD) on vascular function in PAD patients.METHODs: Patients with PaD were randomized to plant-based dietary intervention (PBD group, n = 24) or no specific dietary advice (control group, n = 28). Biochemical parameters, including lipid profile and inflammatory biomarkers, and nitric oxide were measured at baseline and 4 months after dietary intervention. Vascular function including brachial art
APA, Harvard, Vancouver, ISO, and other styles
4

Sosina, A. O., and O. J. Babayemi. "Assessment of farmers' needs in Ibarapa East Local Government area of Oyo State, Nigeria." Nigerian Journal of Animal Production 47, no. 5 (2020): 92–100. http://dx.doi.org/10.51791/njap.v47i5.1352.

Full text
Abstract:
Government and non-government organizations (NGOs) interventions to local farmers in the recent past had not yielded the desired result because these interventions were not tailored towards the needs of farmers. However, most information on the needs of target farmers have been very scanty thus, the need to use a bottom top approach to assess farmers' needs in Ibarapa East, Oyo state. A three-stage sampling technique was used to purposively select about 225 respondents. Parameters measured were household characteristics, farm sizes, farm labor availability, seasonal pattern and need to be asse
APA, Harvard, Vancouver, ISO, and other styles
5

Liu, Chang, Jian-Wen Lu, Zhao-Qing Du, Xue-Min Liu, Yi Lv, and Xu-Feng Zhang. "Association of Preoperative Biliary Drainage with Postoperative Morbidity after Pancreaticoduodenectomy." Gastroenterology Research and Practice 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/796893.

Full text
Abstract:
Background. The advantages or disadvantages of preoperative biliary drainage (PBD) prior to pancreaticoduodenectomy (PD) remain unclear.Methods. A prospectively maintained database was queried for 335 consecutive patients undergoing standard PD surgery between 2009 and 2013. Clinical data and postoperative complications of the 47 patients receiving PBD and 288 patients with early surgery were compared. A matching analysis was also performed between patients receiving or not receiving PBD (no-PBD).Results. The indication for PBD was severe obstructive jaundice (81%) and cholangitis (26%) at the
APA, Harvard, Vancouver, ISO, and other styles
6

Medici, Elphee, Winston J. Craig, and Ian Rowland. "A Comprehensive Analysis of the Nutritional Composition of Plant-Based Drinks and Yogurt Alternatives in Europe." Nutrients 15, no. 15 (2023): 3415. http://dx.doi.org/10.3390/nu15153415.

Full text
Abstract:
Concerns for human and planetary health have led to a shift towards healthier plant-based diets. Plant-based dairy alternatives (PBDA) have experienced exponential market growth due to their lower environmental impact compared to dairy products. However, questions have arisen regarding their suitability as dairy substitutes and their role in food-based dietary guidelines (FBDG). Our study aimed to analyse the nutritional profiles of leading PBDA across Europe and compare them with their dairy counterparts. We examined the nutritional profiles of 309 unflavoured PBDA representing the European m
APA, Harvard, Vancouver, ISO, and other styles
7

Donfrancesco, Renato, Michela Di Trani, Elda Andriola, et al. "Bipolar Disorder in Children With ADHD: A Clinical Sample Study." Journal of Attention Disorders 21, no. 9 (2014): 715–20. http://dx.doi.org/10.1177/1087054714539999.

Full text
Abstract:
Objective: To explore the impact of early-onset bipolar disorder (pediatric bipolar disorder [PBD]) on ADHD. Method: We compared ADHD symptom severity, ADHD subtype distribution, and rates of comorbid and familial psychiatric disorders between 49 ADHD children with comorbid PBD and 320 ADHD children without PBD. Results: Children with ADHD and PBD showed higher scores in the Hyperactive and Inattentive subscales of the ADHD Rating Scale, than children with ADHD alone. The frequency of combined subtype was significantly higher in ADHD children with PBD, than in those with ADHD alone. ADHD child
APA, Harvard, Vancouver, ISO, and other styles
8

Cordeiro, Mara L., Antonio C. Farias, Peter C. Whybrow, et al. "Receiver Operating Characteristic Curve Analysis of Screening Tools for Bipolar Disorder Comorbid With ADHD in Schoolchildren." Journal of Attention Disorders 24, no. 10 (2015): 1403–12. http://dx.doi.org/10.1177/1087054715620897.

Full text
Abstract:
Objective: We compared Child Behavior Checklist (CBCL)-AAA (Attention Problems, Aggressive Behavior, and Anxious/Depressed) and Parent–Young Mania Rating Scale (P-YMRS) profiles in Brazilian children with ADHD, pediatric-onset bipolar disorder (PBD), and PBD + ADHD. Method: Following analyses of variance or Kruskal–Wallis tests with multiple-comparison Least Significant Difference (LSD) or Dunn’s Tests, thresholds were determined by Mann–Whitney U Tests and receiver operating characteristic (ROC) plots. Results: Relative to ADHD, PBD and PBD + ADHD groups scored higher on the Anxious/Depressed
APA, Harvard, Vancouver, ISO, and other styles
9

Ferguson, Lindsay, Sanjib Bhakta, Keith R. Fox, Geoff Wells, and Federico Brucoli. "Synthesis and Biological Evaluation of a Novel C8-Pyrrolobenzodiazepine (PBD) Adenosine Conjugate. A Study on the Role of the PBD Ring in the Biological Activity of PBD-Conjugates." Molecules 25, no. 5 (2020): 1243. http://dx.doi.org/10.3390/molecules25051243.

Full text
Abstract:
Here we sought to evaluate the contribution of the PBD unit to the biological activity of PBD-conjugates and, to this end, an adenosine nucleoside was attached to the PBD A-ring C8 position. A convergent approach was successfully adopted for the synthesis of a novel C8-linked pyrrolo(2,1-c)(1,4)benzodiazepine(PBD)-adenosine(ADN) hybrid. The PBD and adenosine (ADN) moieties were synthesized separately and then linked through a pentynyl linker. To our knowledge, this is the first report of a PBD connected to a nucleoside. Surprisingly, the compound showed no cytotoxicity against murine cells and
APA, Harvard, Vancouver, ISO, and other styles
10

Shi, Jishu, Guolong Zhang, Hua Wu, Christopher Ross, Frank Blecha та Tomas Ganz. "Porcine Epithelial β-Defensin 1 Is Expressed in the Dorsal Tongue at Antimicrobial Concentrations". Infection and Immunity 67, № 6 (1999): 3121–27. http://dx.doi.org/10.1128/iai.67.6.3121-3127.1999.

Full text
Abstract:
ABSTRACT Epithelial cells and phagocytes contain antimicrobial polypeptides that participate in innate host defense. A recently cloned porcine β-defensin, PBD-1, was detected by Northern organ blots exclusively in the tongue epithelium. We generated recombinant PBD-1 peptide by using a baculovirus-insect cell expression system and obtained two forms (PBD-142 and PBD-138), which differed by N-terminal truncation. Only PBD-142 was found in scrapings of the surface of the dorsal tongue or the buccal mucosa. Immunohistochemical staining with antibody to PBD-142revealed that PBD-1 was highly concen
APA, Harvard, Vancouver, ISO, and other styles
11

URBONIENĖ, Ramunė, Loreta KELPŠAITĖ, and Ingrida BORISENKO. "VEGETATION IMPACT ON THE DUNE STABILITY AND FORMATION ON THE LITHUANIAN COAST OF THE BALTIC SEA." JOURNAL OF ENVIRONMENTAL ENGINEERING AND LANDSCAPE MANAGEMENT 23, no. 3 (2015): 230–39. http://dx.doi.org/10.3846/16486897.2015.1009079.

Full text
Abstract:
The aim of this study was to estimate vegetation coverage impact on the sandy beach and protective beach dune ridge (PBD) formation. Studies of the Lithuanian Baltic Sea coastal morphometric parameters and vegetation coverage projection were carried out from 1999 to 2011. In order to evaluate the dependence of the beach and the PBD morphometric parameters on the projection of vegetation coverage changes, correlation analyses were performed. A very strong link between vegetation projection coverage of the PBD top and beach width and incline of the eastern slope of PBD, and western slope vegetat
APA, Harvard, Vancouver, ISO, and other styles
12

Zvinowanda, Douglas, Chengedzai Mafini, and John D. Beneke. "Racial diversity in South African corporate boards and shareholder value creation: A decadal study." International Journal of Management and Sustainability 14, no. 2 (2025): 392–416. https://doi.org/10.18488/11.v14i2.4193.

Full text
Abstract:
This study investigates the influence of board racial diversity (BRD) on shareholder value creation (SVC) of 95 non-financial companies listed on the Johannesburg Stock Exchange (JSE) from 2013 to 2022. The study employed a quantitative quasi-experimental method. The fixed effects model (FEM) was used to test the hypotheses. The results of linear FEM revealed that standard market value added was negatively influenced by the proportion of black directors (PBD), the Blau index for board racial diversity(BI_BRD) and dummies for skewed board (SB), tilted (TB) and balanced board (BB), while positiv
APA, Harvard, Vancouver, ISO, and other styles
13

Arumugham, Kalai Selvan. "KURIKULUM, PENGAJARAN DAN PENTAKSIRAN DARI PERSPEKTIF PELAKSANAAN PENTAKSIRAN BILIK DARJAH." Asian People Journal (APJ) 3, no. 1 (2020): 152–61. http://dx.doi.org/10.37231/apj.2020.3.1.175.

Full text
Abstract:
Abstract: Classroom assessment (PBD) is introduced with the purpose of assessing and measuring the holistic development of a student's learning. PBD needs to be implemented to ensure that students develop an interest and enjoyment of learning. The burden of examination has been fully reduced to ensure that student character building can be carried out from standard one until three. This research is conducted to understand how primary school teachers in Malaysia implement PBD. The main aspects that been researched is on how teachers are integrating curriculum, teaching and assessment and the se
APA, Harvard, Vancouver, ISO, and other styles
14

Sriussadaporn, Suvit, Sukanya Sriussadaporn, Rattaplee Pak-art, et al. "Outcomes of pancreaticoduodenectomy in patients with obstructive jaundice with and without preoperative biliary drainage: a retrospective observational study." Asian Biomedicine 12, no. 5 (2019): 237–41. http://dx.doi.org/10.1515/abm-2019-0025.

Full text
Abstract:
Abstract Background Preoperative biliary drainage (PBD) in patients with obstructive jaundice from periampullary neoplasms may reduce the untoward effects of biliary obstruction and subsequent postoperative complications. However, PBD is associated with bile contamination and increases infectious complications after pancreaticoduodenectomy (PD). Objectives To determine whether PBD is associated with more complications after PD. Methods Patients with obstructive jaundice from periampullary lesions who underwent PD from 2000 to 2015 at our institution were retrospectively enrolled. The cohort wa
APA, Harvard, Vancouver, ISO, and other styles
15

Park, Sunmin. "A Causal and Inverse Relationship between Plant-Based Diet Intake and in a Two-Sample Mendelian Randomization Study." Foods 12, no. 3 (2023): 545. http://dx.doi.org/10.3390/foods12030545.

Full text
Abstract:
A plant-based diet (PBD) has been reported to be linked to metabolic syndrome (MetS) risk in observational studies, but not in causal association studies. We aimed to examine the hypothesis that high PBD exhibited a causal and inverse association with MetS and its components using two-sample Mendelian randomization (MR). PBD was clustered according to food intake, which was assessed by semi-quantitative food frequency questionnaires using a principal component analysis. The instrumental variables were generated using the genome-wide association study (GWAS) of a High-PBD group (≥67th percentil
APA, Harvard, Vancouver, ISO, and other styles
16

Primus, Velerie Wheelervon, and Musirin Mosin. "Pengurusan Pentaksiran Bilik Darjah Murid Berkeperluan Khas dalam Program Pendidikan Inklusif di Sekolah Rendah." Malaysian Journal of Social Sciences and Humanities (MJSSH) 6, no. 8 (2021): 59–68. http://dx.doi.org/10.47405/mjssh.v6i8.903.

Full text
Abstract:
Pentaksiran bilik darjah (PBD) merupakan satu transformasi kurikulum semasa dalam landskap pentaksiran pendidikan negara. Pendekatan utama dalam PBD ialah pentaksiran untuk pembelajaran dan pentaksiran sebagai pembelajaran. Oleh itu, kajian ini bertujuan untuk meneroka pengurusan perancangan PBD Murid Berkeperluan Khas (MBK) dalam Program Pendidikan Inklusif (PPI) sekolah rendah. Reka bentuk kajian ini adalah secara kajian kes yang menggunakan kaedah kualitatif. Empat orang guru di empat buah sekolah yang terlibat dalam mengendalikan PBD dipilih secara purposive sampling sebagai peserta kajian
APA, Harvard, Vancouver, ISO, and other styles
17

Passarotti, Alessandra M., Jacklynn M. Fitzgerald, John A. Sweeney, and Mani N. Pavuluri. "Negative Emotion Interference During a Synonym Matching Task in Pediatric Bipolar Disorder with and without Attention Deficit Hyperactivity Disorder." Journal of the International Neuropsychological Society 19, no. 5 (2013): 601–12. http://dx.doi.org/10.1017/s135561771300012x.

Full text
Abstract:
AbstractThis study examined whether processing of emotional words impairs cognitive performance in acutely ill patients with pediatric bipolar disorder (PBD), with or without comorbid attention-deficit hyperactivity disorder (ADHD), relative to healthy controls (HC). Forty youths with PBD without ADHD, 20 youths with PBD and ADHD, and 29 HC (mean age = 12.97 ± 3.13) performed a Synonym Matching task, where they decided which of two probe words was the synonym of a target word. The three words presented on each trial all had the same emotional valence, which could be negative, positive, or neut
APA, Harvard, Vancouver, ISO, and other styles
18

Zammarchi, Francesca, Simon Corbett, Lauren Adams, et al. "hLL2-Cys-PBD, a New Site-Specifically Conjugated, Pyrrolobenzodiazepine (PBD) Dimer-Based Antibody Drug Conjugate (ADC) Targeting CD22-Expressing B-Cell Malignancies." Blood 128, no. 22 (2016): 4176. http://dx.doi.org/10.1182/blood.v128.22.4176.4176.

Full text
Abstract:
Abstract We previously described the development of hLL2-PBD, an ADC composed of the humanized monoclonal antibody epratuzumab (hLL2) against human CD22, stochastically conjugated to SG3249, a cathepsin B-cleavable valine-alanine PBD payload. SG3249, also known as tesirine, is a potent and clinically validated PBD payload currently being employed in the clinic in three ADCs: the CD25-targeted ADCT-301, the CD19-targeted ADCT-402, both for the treatment of lymphoma and leukemia, and the DDL3-targeted rovalpituzumab tesirine for the treatment of small cell lung cancer. hLL2-PBD demonstrated pote
APA, Harvard, Vancouver, ISO, and other styles
19

Varlashkin, P. G., M. J. D. Low, G. A. Parodi, and C. Morterra. "A Comparison of FT-IR/PA and FT-IR/PBD Spectra of Powders." Applied Spectroscopy 40, no. 5 (1986): 636–41. http://dx.doi.org/10.1366/0003702864508539.

Full text
Abstract:
FT-IR photoacoustic (PA) and also photothermal beam deflection (PBD) spectra were recorded with the same particulate samples (graphite, charcoal, aspirin, and silica) under the same conditions in order to compare the quality of the spectra obtainable with the two techniques. A PA cell fitted with windows for the PBD laser probe beam was used, and PA and PBD spectra of each sample were recorded at 8 cm−1 resolution at each of the four different interferometer scan velocities. Although the overall aspects of FT-IR/PA and FT-IR/PBD spectra are the same, the signal-to-noise ratios of PA spectra ar
APA, Harvard, Vancouver, ISO, and other styles
20

Cavanaugh, Sarah M., Ryan P. Cavanaugh, Gregory E. Gilbert, Elena L. Leavitt, Jennifer K. Ketzis, and Aline B. Vieira. "Short-term amino acid, clinicopathologic, and echocardiographic findings in healthy dogs fed a commercial plant-based diet." PLOS ONE 16, no. 10 (2021): e0258044. http://dx.doi.org/10.1371/journal.pone.0258044.

Full text
Abstract:
Consumer demand for commercially prepared plant-based (PB) dog food is increasing, but studies evaluating the short- or long-term effects of PB diets on canine health are lacking. The objective of this study was to assess the short-term amino acid (AA), clinicopathologic, and echocardiographic findings in 34 client-owned dogs fed a commercial extruded plant-based diet (PBD) in which pea protein was the primary protein source and 4 control dogs fed a commercial extruded traditional diet (TD). Plasma AA and whole blood taurine concentrations were measured in dogs at baseline and after 4 weeks on
APA, Harvard, Vancouver, ISO, and other styles
21

Varlashkin, P. G., and M. J. D. Low. "FT-IR Photothermal Beam Deflection Spectroscopy of Solids Submerged in Liquids." Applied Spectroscopy 40, no. 8 (1986): 1170–76. http://dx.doi.org/10.1366/0003702864507783.

Full text
Abstract:
FT-IR photothermal beam deflection (PBD) spectra were recorded of solids submerged in liquid CCl4 and in C2Cl4. Some PBD effects are described. Submerging the sample leads to PBD signals 40 times larger than those found with the sample in air, but the signal-to-noise ratio of FT-IR/PBD spectra is only increased by a factor of ten. Certain aspects of the technique and its utility are discussed.
APA, Harvard, Vancouver, ISO, and other styles
22

Huang, Jing, Antian Wang, Chao Huang, et al. "Generation of Marker-Free pbd-2 Knock-in Pigs Using the CRISPR/Cas9 and Cre/loxP Systems." Genes 11, no. 8 (2020): 951. http://dx.doi.org/10.3390/genes11080951.

Full text
Abstract:
Porcine β-defensin 2 (PBD-2), expressed by different tissues of pigs, is a multifunctional cationic peptide with antimicrobial, immunomodulatory and growth-promoting abilities. As the latest generation of genome-editing tool, CRISPR/Cas9 system makes it possible to enhance the expression of PBD-2 in pigs by site-specific knock-in of pbd-2 gene into the pig genome. In this study, we aimed to generate marker-free pbd-2 knock-in pigs using the CRISPR/Cas9 and Cre/loxP systems. Two copies of pbd-2 gene linked by a T2A sequence were inserted into the porcine Rosa26 locus through CRISPR/Cas9-mediate
APA, Harvard, Vancouver, ISO, and other styles
23

Kanbayti, Ibrahem, Judith Akwo, Akwa Erim, Ekaete Ukpong, and Ernest Ekpo. "Mammographic Breast Density at Breast Cancer Diagnosis and Breast Cancer-Specific Survival." Diagnostics 14, no. 21 (2024): 2382. http://dx.doi.org/10.3390/diagnostics14212382.

Full text
Abstract:
Background: Breast density impacts upon breast cancer risk and recurrence, but its influence on breast cancer-specific survival is unclear. This study examines the influence of mammographic breast density (MBD) at diagnosis on breast cancer-specific survival. Methods: The data of 224 patients diagnosed with breast cancer were analyzed. Two area-based MBD measurement tools—AutoDensity and LIBRA—were used to measure MBD via a mammogram of the contralateral breast acquired at the time of diagnosis. These patients were split into two groups based on their percent breast density (PBD): high (PBD ≥
APA, Harvard, Vancouver, ISO, and other styles
24

Biscotti, Paola, Massimiliano Tucci, Donato Angelino, et al. "Effects of Replacing Cow’s Milk with Plant-Based Beverages on Potential Nutrient Intake in Sustainable Healthy Dietary Patterns: A Case Study." Nutrients 16, no. 18 (2024): 3083. http://dx.doi.org/10.3390/nu16183083.

Full text
Abstract:
More consumers are replacing cow’s milk (CM) with plant-based drinks (PBD), but data indicating the nutritional impact are limited. This theoretical study aims to assess the effect of substituting CM with PBD sold in Italy on nutrient intake within two dietary patterns: one aligned with the EAT-Lancet Commission reference diet adapted to Italian food habits (EAT-IT) and another one in line with the Italian Dietary Guidelines (IDG). Nutrition information from 368 PBD were collected and categorized according to their descriptive name and their fortification or not with calcium (Ca- and nCa-forti
APA, Harvard, Vancouver, ISO, and other styles
25

Bu, Fei, Nengmin Wang, Qi Jiang, and Xiang Tian. "Research on Privacy-by-Design Behavioural Decision-Making of Information Engineers Considering Perceived Work Risk." Systems 12, no. 7 (2024): 250. http://dx.doi.org/10.3390/systems12070250.

Full text
Abstract:
Privacy by design (PbD) has attracted considerable attention from researchers and information security experts due to its enormous potential for protecting private information and improving the privacy and security quality of information technology products. The adoption of PbD among information engineers is currently limited owing to its innovativeness and the distinctive traits of the information technology industry. Utilising the Technology Acceptance Model as a framework, this study innovatively explores the pivotal factors and mechanisms that influence information engineers’ decision-maki
APA, Harvard, Vancouver, ISO, and other styles
26

Mintziras, Ioannis, Elisabeth Maurer, Veit Kanngiesser, Michael Lohoff, and Detlef K. Bartsch. "Preoperative Bacterobilia Is an Independent Risk Factor of SSIs after Partial PD." Digestive Surgery 37, no. 5 (2020): 428–35. http://dx.doi.org/10.1159/000508127.

Full text
Abstract:
Introduction: The impact of bacterobilia on postoperative surgical and infectious complications after partial pancreaticoduodenectomy (PD) is still a matter of debate. Methods: All patients undergoing PD with and without a preoperative biliary drainage (PBD) with complete information regarding microbial bile colonization were included. Logistic regression was applied to assess the influence of bacterobilia on postoperative outcome. Results: One hundred seventy patients were retrospectively analysed. Clinically relevant postoperative complications (Clavien-Dindo ≥ III) occurred in 40 (23.5%) pa
APA, Harvard, Vancouver, ISO, and other styles
27

Zhao, Xue Zhi, Kohei Tsuji, David Hymel, and Terrence R. Burke. "Development of Highly Selective 1,2,3-Triazole-containing Peptidic Polo-like Kinase 1 Polo-box Domain-binding Inhibitors." Molecules 24, no. 8 (2019): 1488. http://dx.doi.org/10.3390/molecules24081488.

Full text
Abstract:
Members of the polo-like kinase (Plk) family of serine/threonine protein kinases play crucial roles in cell cycle regulation and proliferation. Of the five Plks (Plk1–5), Plk1 is recognized as an anticancer drug target. Plk1 contains multiple structural components that are important for its proper biological function. These include an N-terminal catalytic domain and a C-terminal non-catalytic polo-box domain (PBD). The PBD binds to phosphothreonine (pT) and phosphoserine-containing sequences. Blocking PBD-dependent interactions offers a potential means of down-regulating Plk1 function that is
APA, Harvard, Vancouver, ISO, and other styles
28

Cao, Weifang, Haoran Chen, Qing Jiao, et al. "Altered Functional Integration in the Salience and Default Mode Networks in Euthymic Pediatric Bipolar Disorder." Neural Plasticity 2020 (October 9, 2020): 1–9. http://dx.doi.org/10.1155/2020/5853701.

Full text
Abstract:
Accumulating studies demonstrate emotional and cognitive dysregulation in the euthymic period of pediatric bipolar disorder (PBD). However, the relative contribution of functional integration in human brain to disturbed emotion and cognitive function in the euthymic PBD patients remains unclear. In this study, 16 euthymic PBD patients and 16 healthy controls underwent resting-state functional magnetic resonance imaging. A data-driven functional connectivity analysis was used to investigate functional connectivity changes of the euthymic PBD. Compared with healthy controls, the euthymic PBD exh
APA, Harvard, Vancouver, ISO, and other styles
29

Nir, Moira Marx, and Robert E. Cohen. "Blends of Crystallizable Polybutadiene Isomers." Rubber Chemistry and Technology 66, no. 2 (1993): 295–303. http://dx.doi.org/10.5254/1.3538313.

Full text
Abstract:
Abstract Precipitated blends of two crystallizable polybutadiene (PBD) isomers were characterized in terms of crystallization and phase behavior, morphology, and tensile mechanical properties. The isomers are syndiotactic 1,2 PBD (Mv=32.5 kg/mol) and trans 1,4 PBD (Mv=425 kg/mol). The blends exhibit heterogeneous behavior over the full range of composition. Using a solvent precipitation method, blends are obtained with heterogeneity on the order of 1 µm. Tensile properties of these semicrystalline blends are generally intermediate between those of the corresponding semicrystalline homopolymers
APA, Harvard, Vancouver, ISO, and other styles
30

Primus, Velerie Wheelervon, and Musirin Mosin. "Strategi Pengurusan Evidens Pentaksiran Bilik Darjah Murid Berkeperluan Khas dalam Program Inklusif Sekolah Rendah." Malaysian Journal of Social Sciences and Humanities (MJSSH) 6, no. 9 (2021): 282–93. http://dx.doi.org/10.47405/mjssh.v6i9.1026.

Full text
Abstract:
Kajian ini bertujuan untuk meneroka Strategi Pengurusan Evidens Pentaksiran Bilik Darjah Bagi Murid Masalah Pembelajaran dalam Program Pendidikan Inklusif di sekolah rendah. Surat siaran KPM bilangan 14, 2018 menyatakan pemansuhan amalan peperiksaan pertengahan dan akhir tahun bagi murid tahap 1, telah dimansuhkan bermula 2018. Peperiksaan yang sebelum ini dijalankan telah digantikan dengan sistem pentaksiran yang lebih objektif (LPM, 2018). Murid masalah pembelajaran dalam program inklusif juga tidak terkecuali daripada sistem pentaksiran yang baharu ini. Namun demikian, pelaksanaan program i
APA, Harvard, Vancouver, ISO, and other styles
31

Okabe, Hirohisa. "Clinical impact of preoperative biliary drainage on postoperataive complications in pancreaticoduodenectomy." Journal of Clinical Oncology 37, no. 4_suppl (2019): 302. http://dx.doi.org/10.1200/jco.2019.37.4_suppl.302.

Full text
Abstract:
302 Background: Biliary drainage is sometimes necessary for patients undergoing pancreaticoduodenectomy (PD) because of tumor invasion to the biliary tract. The current study aims to explore the clinical impact of preoperative biliary drainage (PBD) on postoperative complication in PD. Methods: One hundred sixty-six patients who underwent PD from 2012–2017 were enrolled in this study. Clinical impact of PBD on clinical course was examined. Results: There were 66 patients (40%) undergoing PBD. Patients with PBD showed significantly higher infection rate of bile juice collected at surgery (p &lt
APA, Harvard, Vancouver, ISO, and other styles
32

Marnizam, Fara Izzati, and Siti Rahaimah Ali. "Evaluation of The Implementation of Classroom Assessment (PBD) Among Primary School Mathematics Teachers." Jurnal Pendidikan Sains dan Matemaitk Malaysia 11, no. 2 (2021): 81–94. https://doi.org/10.37134/jpsmm.vol11.2.7.2021.

Full text
Abstract:
Pentaksiran Bilik Darjah (PBD) or Classroom Assessment was introduced to ensure a holistic assessment is established towards the pupils and not focusing solely on examination. This research is carried out to evaluate the implementation of PBD among Mathematics teachers in some primary schools in Gombak District, Selangor. This research consists of two research objectives. The CIPP Evaluation Model is used as the research framework which consists of context evaluation, input, process and product. The research sample are from 114 primary school Mathematics teachers from Gombak District and they
APA, Harvard, Vancouver, ISO, and other styles
33

Shim, Sojin, Jan Unkelbach, Anna Landsmann, and Andreas Boss. "Quantitative Study on the Breast Density and the Volume of the Mammary Gland According to the Patient’s Age and Breast Quadrant." Diagnostics 13, no. 21 (2023): 3343. http://dx.doi.org/10.3390/diagnostics13213343.

Full text
Abstract:
Objectives: Breast density is considered an independent risk factor for the development of breast cancer. This study aimed to quantitatively assess the percent breast density (PBD) and the mammary glands volume (MGV) according to the patient’s age and breast quadrant. We propose a regression model to estimate PBD and MGV as a function of the patient’s age. Methods: The breast composition in 1027 spiral breast CT (BCT) datasets without soft tissue masses, calcifications, or implants from 517 women (57 ± 8 years) were segmented. The breast tissue volume (BTV), MGV, and PBD of the breasts were me
APA, Harvard, Vancouver, ISO, and other styles
34

Jiao, W., Q. Ma, X. Lv, A. Shan та Z. Li. "Gene expression and tissue distribution of β-defensins in Chinese Min pigs and Landrace pigs". Czech Journal of Animal Science 62, No. 4 (2017): 178–83. http://dx.doi.org/10.17221/84/2015-cjas.

Full text
Abstract:
β-Defensins are a major group of mammalian antimicrobial peptides and play an important role in innate and adaptive immunity due to their antimicrobial, chemotactic, and regulatory activities. In this study, the tissue distribution of porcine β-defensin (pBD-1, pBD-2, and pBD-3) gene expression was determined using real-time polymerase chain reaction in 14-day-old Chinese Min pigs and Landrace pigs. The results showed that in the two breeds, pBD-1 and pBD-2 were primarily expressed in the tongue and kidney, respectively. The pBD-3 genes in Min pigs and Landrace pigs were abundant in the heart
APA, Harvard, Vancouver, ISO, and other styles
35

Fazlollahi, Narges, Amir Anushiravani, Maryam Rahmati, et al. "Safety and Efficacy of Graded Gradual Pneumatic Balloon Dilation in Idiopathic Achalasia Patients: A 24-Year Single-Center Experience." Archives of Iranian Medicine 24, no. 12 (2021): 862–68. http://dx.doi.org/10.34172/aim.2021.129.

Full text
Abstract:
Background: Pneumatic balloon dilation (PBD) is a first line treatment for idiopathic achalasia. Here we report the safety and efficacy of graded gradual PBD on short and long-term follow-up. Methods: We evaluated 1370 idiopathic achalasia patients over a period of 24 years (1994-2018), prospectively. 216 patients did not undergo PBD due to comorbid diseases. Ultimately, 1092 achalasia patients were enrolled. All patients underwent graded gradual PBD, with repeat dilation if symptoms relapsed. Response to treatment was evaluated by Vantrappen scoring system. Results: Of 1092 achalasia patients
APA, Harvard, Vancouver, ISO, and other styles
36

Lee, Dong-Kyun, Hyeongrae Lee, Vin Ryu, Sung-Wan Kim, and Seunghyong Ryu. "Different patterns of white matter microstructural alterations between psychotic and non-psychotic bipolar disorder." PLOS ONE 17, no. 3 (2022): e0265671. http://dx.doi.org/10.1371/journal.pone.0265671.

Full text
Abstract:
This study aimed to investigate alterations in white matter (WM) microstructure in patients with psychotic and non-psychotic bipolar disorder (PBD and NPBD, respectively). We used 3T-magnetic resonance imaging to examine 29 PBD, 23 NPBD, and 65 healthy control (HC) subjects. Using tract-based spatial statistics for diffusion tensor imaging data, we compared fractional anisotropy (FA) and mean diffusion (MD) pairwise among the PBD, NPBD, and HC groups. We found several WM areas of decreased FA or increased MD in the PBD and NPBD groups compared to HC. PBD showed widespread FA decreases in the c
APA, Harvard, Vancouver, ISO, and other styles
37

Yan, Fang, Guangmei Liu, Tingting Chen, Xiaochen Fu, and Miao-Miao Niu. "Structure-Based Virtual Screening and Biological Evaluation of Peptide Inhibitors for Polo-Box Domain." Molecules 25, no. 1 (2019): 107. http://dx.doi.org/10.3390/molecules25010107.

Full text
Abstract:
The polo-box domain of polo-like kinase 1 (PLK1-PBD) is proved to have crucial roles in cell proliferation. Designing PLK1-PBD inhibitors is challenging due to their poor cellular penetration. In this study, we applied a virtual screening workflow based on a combination of structure-based pharmacophore modeling with molecular docking screening techniques, so as to discover potent PLK1-PBD peptide inhibitors. The resulting 9 virtual screening peptides showed affinities for PLK1-PBD in a competitive binding assay. In particular, peptide 5 exhibited an approximately 100-fold increase in inhibitor
APA, Harvard, Vancouver, ISO, and other styles
38

Pei Juan, Ng, Saemah Rahman, and Shahlan Surat. "Tahap Pengetahuan, Kemahiran dan Kesediaan Guru Terhadap Pelaksanaan Pentaksiran Bilik Darjah (PBD)." Malaysian Journal of Social Sciences and Humanities (MJSSH) 8, no. 5 (2023): e002339. http://dx.doi.org/10.47405/mjssh.v8i5.2339.

Full text
Abstract:
Pentaksiran Bilik Darjah adalah salah satu cara yang digunakan untuk mentaksir kemahiran dan kefahaman murid. Pelaksanaan PBD dapat memperolehi maklumat tentang perkembangan dan pencapaian murid bagi setiap mata pelajaran kepada guru. Faktor yang penting dalam menjayakan pelaksanaan PBD adalah tahap pengetahuan, kemahiran dan kesediaan guru. Kajian ini dilakukan untuk mengenal pasti tahap pengetahuan, tahap kemahiran dan tahap kesediaan guru dalam pelaksanaan PBD. Seramai 83 orang guru yang berasal dari 5 buah sekolah rendah kategori A Program Transformasi Sekolah 2025(TS25) di daerah Kuala Li
APA, Harvard, Vancouver, ISO, and other styles
39

Passariello, R., P. Pavone, P. Rossi, et al. "Percutaneous Biliary Drainage in Neoplastic Jaundice." Acta Radiologica. Diagnosis 26, no. 6 (1985): 681–88. http://dx.doi.org/10.1177/028418518502600607.

Full text
Abstract:
Technical and clinical data concerning 731 controlled patients submitted to nonsurgical percutaneous biliary drainage (PBD) for preoperative or palliative purposes were collected from eight institutions. Using a computerized analysis program, general and special statistics were obtained, with special attention given to 536 neoplastic cases. Technical success, type, level and nature of the lesions, purpose of drainage, surgery performed, complications, and other clinical and technical information were considered and compared with the clinical results. Statistically significant data were obtaine
APA, Harvard, Vancouver, ISO, and other styles
40

Arumugham, Kalai Selvan. "Pentaksiran Bilik Darjah (PBD) Dalam Norma Baharu: Pemimpin Pertengahan Dalam Mengupayakan Pelaksanaan PBD Berasaskan Teknologi." Sains Insani 7, no. 1 (2022): 37–43. http://dx.doi.org/10.33102/sainsinsani.vol7no1.354.

Full text
Abstract:
Pengenalan PBD adalah bertujuan untuk memastikan perkembangan pembelajaran seseorang pelajar dapat diukur secara berterusan. Walau bagaimanapun, sejak pengajaran dan pembelajaran dari rumah (PdPr) diperkenalkan, guru menghadapi masalah untuk melaksanakan PBD dengan berkesan. Kajian ini dijalankan untuk meneroka dan memahami cara pemimpin pertengahan memainkan peranan sebagai seorang pemimpin instruksional dan seterusnya membangunkan guru-guru di sekolah untuk memastikan guru-guru dapat melaksanakan PBD dengan berkesan dengan penggunaan teknologi. Seramai lapan orang Guru Kanan Mata Pelajaran (
APA, Harvard, Vancouver, ISO, and other styles
41

Lokman, Hairul Faiezi, Norazilawati Abdullah, Mazlina Che Mustafa, Mazarul Hasan Mohamad Hanapi, Saniah Sembak, and Vijaya Letchumy Baskaran. "The Impact of Classroom-Based Assessment (CBA) Implementation on the Performance of B40 Pre-School and Primary School Students." International Journal of Learning, Teaching and Educational Research 23, no. 7 (2024): 435–60. http://dx.doi.org/10.26803/ijlter.23.7.22.

Full text
Abstract:
Classroom-Based Assessment (PBD) is applied in the education system in Malaysia. It substitutes the public examination system at the primary school level and gives prominence to summative and formative assessment holistically. This case study was conducted to identify the effectiveness and challenges of PBD implementation on the development of students, specifically the B40 group of pre-school and primary school students. To obtain research data, an in-depth interview instrument was conducted on 13 study participants from a quota sample. Interview findings were analyzed to form themes and were
APA, Harvard, Vancouver, ISO, and other styles
42

Miller, J. M., and M. J. Van Der Maaten. "Experimentally induced infectious bovine rhinotracheitis virus infection during early pregnancy: Effect on the bovine corpus luteum and conceptus." American Journal of Veterinary Research 47, no. 2 (1986): 223–28. https://doi.org/10.2460/ajvr.1986.47.02.223.

Full text
Abstract:
SUMMARY Pairs of heifers were inoculated iv with infectious bovine rhinotracheitis virus on postbreeding days (pbd) 7, 14, 21, or 28, and were euthanatized 13 to 15 days after inoculation. Reproductive tracts were examined for cytopathologic changes (light microscopy), virus (cell culture), and viral antigen (immunohistochemical evaluation). Heifers inoculated on pbd 7 or 14 had mild oophoritis characterized by foci of necrosis and mononuclear cell accumulations in the corpus luteum. Most of these heifers also had a few necrotic follicles in at least one ovary. Heifers inoculated on pbd 21 or
APA, Harvard, Vancouver, ISO, and other styles
43

Rahman, Khondaker M., Helena Rosado, Joao B. Moreira, et al. "Antistaphylococcal activity of DNA-interactive pyrrolobenzodiazepine (PBD) dimers and PBD-biaryl conjugates." Journal of Antimicrobial Chemotherapy 67, no. 7 (2012): 1683–96. http://dx.doi.org/10.1093/jac/dks127.

Full text
APA, Harvard, Vancouver, ISO, and other styles
44

Parry, Peter, Stephen Allison, and Tarun Bastiampillai. "The geography of a controversial diagnosis: A bibliographic analysis of published academic perspectives on ‘paediatric bipolar disorder’." Clinical Child Psychology and Psychiatry 24, no. 3 (2019): 529–45. http://dx.doi.org/10.1177/1359104519836700.

Full text
Abstract:
Background: The hypothesis that bipolar disorder presents before puberty with atypical mania has proved to be controversial. Published academic perspectives on the validity of Paediatric Bipolar Disorder (PBD) appear to vary between the United States and the rest of the world. Methods: We examined the perspectives of articles citing four seminal articles. The citing articles were grouped as either supportive or non-supportive of the PBD hypothesis, and the perspectives of the articles by US authors were compared with those by non-US authors. Results: There were 787 citing articles commenting o
APA, Harvard, Vancouver, ISO, and other styles
45

Li, Lei. "Ternary Memristic Effect of Trilayer-Structured Graphene-Based Memory Devices." Nanomaterials 9, no. 4 (2019): 518. http://dx.doi.org/10.3390/nano9040518.

Full text
Abstract:
A tristable memory device with a trilayer structure utilizes poly(methyl methacrylate) (PMMA) sandwiched between double-stacked novel nanocomposite films that consist of 2-(4-tert-butylphenyl)-5-(4-biphenylyl)-1,3,4-oxadiazole (PBD) doped with graphene oxide (GO). We successfully fabricated devices consisting of single and double GO@PBD nanocomposite films embedded in polymer layers. These devices had binary and ternary nonvolatile resistive switching behaviors, respectively. Binary memristic behaviors were observed for the device with a single GO@PBD nanocomposite film, while ternary behavior
APA, Harvard, Vancouver, ISO, and other styles
46

Yang, Xi, Yu-Ting Cheng, Mei-Fang Tan, et al. "Overexpression of Porcine Beta-Defensin 2 Enhances Resistance to Actinobacillus pleuropneumoniae Infection in Pigs." Infection and Immunity 83, no. 7 (2015): 2836–43. http://dx.doi.org/10.1128/iai.03101-14.

Full text
Abstract:
To reduce the need for antibiotics in animal production, alternative approaches are needed to control infection. We hypothesized that overexpression of native defensin genes will provide food animals with enhanced resistance to bacterial infections. In this study, recombinant porcine beta-defensin 2 (PBD-2) was overexpressed in stably transfected PK-15 porcine kidney cells. PBD-2 antibacterial activities againstActinobacillus pleuropneumoniae, an important respiratory pathogen causing porcine contagious pleuropneumonia, were evaluated on agar plates. Transgenic pigs constitutively overexpressi
APA, Harvard, Vancouver, ISO, and other styles
47

Widodo, Budi, Iswan Abbas Nusi, and Titong Sugihartono. "Effect of Pneumatic Balloon Dilation to The Changes of Eckardt Score in Patient With Achalasia." Biomolecular and Health Science Journal 3, no. 1 (2020): 1. http://dx.doi.org/10.20473/bhsj.v3i1.17938.

Full text
Abstract:
Introduction: Achalasia is an esophageal motility disorder, but its pathogenesis remains unclear. The highest incidence is among adults aged 30 – 60 years with the prevalence of 10/100.000 population. Diagnosis of achalasia is based on symptoms and upper endoscopy, barium esophagogram, and esophageal manometry. Pneumatic Balloon Dilation (PBD) is one of the treatment options, whether it is fluoroscopy-guided or direct endoscopy guided. This study aims to analyze the effect of PBD on the changes of Eckardt score among achalasia patients.Methods: An analytical observational study with a retrospe
APA, Harvard, Vancouver, ISO, and other styles
48

Choudhary, Sanjiv, Ankita Srivastava, Ariharasudhan Varadharajan, and Rijavi Choudhary. "Multiple cutaneous and mucocutaneous lesions as manifestations of pseudo-Behçet’s disease." BMJ Case Reports 16, no. 6 (2023): e255669. http://dx.doi.org/10.1136/bcr-2023-255669.

Full text
Abstract:
Pseudo-Behçet’s disease (PBD) is a close clinical mimicker of Behçet’s disease (BD) which can present with orogenital ulceration and uveitis. However, these manifestations in PBD are associated with occult tuberculosis. Sometimes, diagnosis of PBD is established retrospectively when the lesions respond to anti-tubercular therapy (ATT). We here describe a case who presented with a penile ulcer, initially suspected to be a sexually transmitted infection, but was later diagnosed as PBD and resulted in complete healing with ATT. Knowledge about this condition is essential to prevent misdiagnosis a
APA, Harvard, Vancouver, ISO, and other styles
49

Zhou, Yunjiang, Fang Yan, Xiangyun Huo, and Miao-Miao Niu. "Discovery of a Potent PLK1-PBD Small-Molecule Inhibitor as an Anticancer Drug Candidate through Structure-Based Design." Molecules 24, no. 23 (2019): 4351. http://dx.doi.org/10.3390/molecules24234351.

Full text
Abstract:
Polo-box domain of polo-like kinase 1 (PLK1-PBD) has a pivotal role in cell proliferation and could be implicated as a potential anticancer target. Although some small-molecule inhibitors have been developed, their clinical application has been restricted by the poor selectivity. Therefore, there is an urgent need to develop effective PLK1-PBD inhibitors. Herein, we have developed a virtual screening protocol to find PLK1-PBD inhibitors by using combination of structure-based pharmacophore modeling and molecular docking. This protocol was successfully applied to screen PLK1-PBD inhibitors from
APA, Harvard, Vancouver, ISO, and other styles
50

Alnajrani, Hussain Mutlaq, and Azah Anir Norman. "The Effects of Applying Privacy by Design to Preserve Privacy and Personal Data Protection in Mobile Cloud Computing: An Exploratory Study." Symmetry 12, no. 12 (2020): 2039. http://dx.doi.org/10.3390/sym12122039.

Full text
Abstract:
Mobile cloud computing (MCC) is a domain that stemmed from advances in mobile technology and cloud computing. Although debate continues about the best strategies to preserve privacy and personal data protection in MCC, it is essential to explore the effects of applying privacy by design (PbD) to preserve privacy and personal data protection in MCC. PbD is a general philosophy that demonstrates privacy should not be overviewed as an afterthought, but rather as a first-class requirement in the design of IT systems. This study explores the effects of applying PbD to preserve privacy and personal
APA, Harvard, Vancouver, ISO, and other styles
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!