Academic literature on the topic 'PBLs model'

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Journal articles on the topic "PBLs model"

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Lopez-Coto, Israel, Micheal Hicks, Anna Karion, et al. "Assessment of Planetary Boundary Layer Parameterizations and Urban Heat Island Comparison: Impacts and Implications for Tracer Transport." Journal of Applied Meteorology and Climatology 59, no. 10 (2020): 1637–53. http://dx.doi.org/10.1175/jamc-d-19-0168.1.

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AbstractAccurate simulation of planetary boundary layer height (PBLH) is key to greenhouse gas emission estimation, air quality prediction, and weather forecasting. This paper describes an extensive performance assessment of several Weather Research and Forecasting (WRF) Model configurations in which novel observations from ceilometers, surface stations, and a flux tower were used to study their ability to reproduce the PBLH and the impact that the urban heat island (UHI) has on the modeled PBLHs in the greater Washington, D.C., area. In addition, CO2 measurements at two urban towers were compared with tracer transport simulations. The ensemble of models used four PBL parameterizations, two sources of initial and boundary conditions, and one configuration including the building energy parameterization urban canopy model. Results have shown low biases over the whole domain and period for wind speed, wind direction, and temperature, with no drastic differences between meteorological drivers. We find that PBLH errors are mostly positively correlated with sensible heat flux errors and that modeled positive UHI intensities are associated with deeper modeled PBLs over the urban areas. In addition, we find that modeled PBLHs are typically biased low during nighttime for most of the configurations with the exception of those using the MYNN parameterization, and these biases directly translate to tracer biases. Overall, the configurations using the MYNN scheme performed the best, reproducing the PBLH and CO2 molar fractions reasonably well during all hours and thus opening the door to future nighttime inverse modeling.
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Li, Lixian, Zijing Yang, Yawen Hou, and Zheng Chen. "Moving beyond the Cox proportional hazards model in survival data analysis: a cervical cancer study." BMJ Open 10, no. 7 (2020): e033965. http://dx.doi.org/10.1136/bmjopen-2019-033965.

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ObjectivesThis study explored the prognostic factors and developed a prediction model for Chinese-American (CA) cervical cancer (CC) patients. We compared two alternative models (the restricted mean survival time (RMST) model and the proportional baselines landmark supermodel (PBLS model, producing dynamic prediction)) versus the Cox proportional hazards model in the context of time-varying effects.Setting and data sourcesA total of 713 CA women with CC and available covariates (age at diagnosis, International Federation of Gynecology and Obstetrics (FIGO) stage, lymph node metastasis and radiation) from the Surveillance, Epidemiology and End Results database were included.DesignWe applied the Cox proportional hazards model to analyse the all-cause mortality with the proportional hazards assumption. Additionally, we applied two alternative models to analyse covariates with time-varying effects. The performances of the models were compared using the C-index for discrimination and the shrinkage slope for calibration.ResultsOlder patients had a worse survival rate than younger patients. Advanced FIGO stage patients showed a relatively poor survival rate and low life expectancy. Lymph node metastasis was an unfavourable prognostic factor in our models. Age at diagnosis, FIGO stage and lymph node metastasis represented time-varying effects from the PBLS model. Additionally, radiation showed no impact on survival in any model. Dynamic prediction presented a better performance for 5-year dynamic death rates than did the Cox proportional hazards model.ConclusionsWith the time-varying effects, the RMST model was suggested to explore diagnosis factors, and the PBLS model was recommended to predict a patient’s w-year dynamic death rate.
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Kim, Hyung-Yong, Jason Mott, Ning Zhi, Tomoko Tajima, and Yasuko Rikihisa. "Cytokine Gene Expression by Peripheral Blood Leukocytes in Horses Experimentally Infected with Anaplasma phagocytophila." Clinical and Vaccine Immunology 9, no. 5 (2002): 1079–84. http://dx.doi.org/10.1128/cdli.9.5.1079-1084.2002.

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ABSTRACT Human granulocytic ehrlichiosis (HGE), a tick-borne zoonosis, is caused by an obligatory intragranulocytic bacterium, the HGE agent, a strain of Anaplasma phagocytophila. The equine model of HGE is considered valuable in understanding pathogenic and immune mechanisms of HGE. In the present study, cytokine mRNA expression by peripheral blood leukocytes (PBLs) in horses was examined during the course of infection by intravenous inoculation of A. phagocytophila or by allowing feeding by infected ticks. The p44 genes encoding the major outer membrane protein P44s of A. phagocytophila were detected by PCR in PBLs of all four horses from 4 to 20 days postexposure. During the 20-day infection period, interleukin-1β (IL-1β) and tumor necrosis factor alpha (TNF-α) mRNA expression was upregulated in PBLs of all four horses, and IL-8 mRNA expression was upregulated in three horses. Gamma interferon, IL-10, and IL-12 p35 mRNAs were weakly expressed in only one horse each. IL-2, IL-4, IL-6, and IL-12 p40 mRNA expression , however, could not be detected in the PBLs of any of the four horses. These results suggest that IL-1β, TNF-α, and IL-8 generation during A. phagocytophila infection has a primary role in HGE pathogenesis and immunomodulation.
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Lutz, Eric R., Srikanta Jana, Lakshmi Rudraraju, et al. "Superior Efficacy of CAR-T Cells Using Marrow-Infiltrating Lymphocytes (MILsTM) As Compared to Peripheral Blood Lymphocytes (PBLs)." Blood 134, Supplement_1 (2019): 4437. http://dx.doi.org/10.1182/blood-2019-130629.

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Background The type of T cell used in generating chimeric antigen receptor (CAR) T cells is an important choice. Evidence suggests that T cells that are early in the effector/memory differentiation pathway with more stemness and greater potential to persist are better than more differentiated T cells with less stemness that are more readily exhausted and have less potential to persist. Marrow-infiltrating Lymphocytes (MILsTM) is a novel form of adoptive T cell therapy composed of patient-autologous, polyclonal CD4 and CD8 T cells that are activated and expanded from the bone marrow. Genetically unmodified MILsTM have demonstrated antitumor activity in patients with multiple myeloma and are being developed for several other tumor types, including non-small cell lung cancer and other solid tumors. Distinguishing features of bone marrow T cells used to produce MILsTM include their memory phenotype, inherent tumor antigen-specificity, higher CD8:CD4 ratio and ability to persist long-term when compared to peripheral blood lymphocytes (PBLs) which is the T cell source used to produce currently approved CAR-T therapies. Based on these differences, we hypothesize that MILsTM provide a more robust and better fit platform for CAR-T therapy compared to PBLs. Using a CD38-specific, 4-1BB/CD3z-signaling CAR as an initial model, we have demonstrated the feasibility of producing CAR-modified MILsTM (CAR-MILsTM) and showed that CAR-MILsTM demonstrate superior killing in vitro compared to CAR-T cells generated from patient-matched PBLs (CAR-PBLs). Herein, we build on our previous data and add a second BCMA-specific CAR model. We use the two multiple myeloma model systems to compare cytolytic potential, functionality, and expression of phenotypic markers of memory, stemness and exhaustion between patient-matched CAR-MILsTM and CAR-PBLs. Methods Matched pairs of CAR-MILsTM and CAR-PBLs were produced from the bone marrow and blood of multiple myeloma patients. Two different in vitro cytotoxicity assays, the RTCA xCelligence real-time impedance and FACS assays, were used to evaluate antigen-specific killing of target tumor cells. Functionality of CD4 and CD8 CAR-T cells, at the single-cell level, was evaluated by measuring the secretion of 32 cytokines and chemokines following in vitro antigen-specific stimulation using IsoPlexis IsoCode chips and analyzed using IsoPeak. Expression of markers of T cell memory (CD45RO & CCR7/CD62L), stemness (CD27) and exhaustion (PD1 & TIM3) on CAR-MILsTM and CAR-PBLs prior to and following antigen-specific stimulation was evaluated by flow-cytometry (FACS). Results CAR-MILsTM demonstrated superior killing of tumor target cells in vitro, regardless of the antigen specificity of the CAR, when compared to matched CAR-PBLs and this superiority persisted even upon repeated antigen encounter - a factor that may be critical in guaranteeing better anti-tumor efficacy and persistence. CAR-MILsTM demonstrated increased polyfunctionality (secretion of 2+ cytokines per cell) and an increased polyfunctional strength index (PSI) following antigen-stimulation compared to CAR-PBL in both CD4 and CD8 T cells. The enhanced PSI in CAR-MILsTM was predominately mediated by effector, stimulatory and chemoattractive proteins associated with antitumor activity including Granzyme B, IFNg, IL-8, MIP1a and MIP1b. Coincidentally, increased PSI and enhanced secretion of these same proteins was reported to be associated with improved clinical responses in patients with Non-Hodgkin lymphoma treated with CD19-specific CAR-T therapy. Expression of memory markers on CD4 and CD8 T cells were similar in CAR-MILsTM and CAR-PBLs both prior to and following antigen-stimulation. Although expression of CD27, PD1 and TIM3 were similar at baseline, CAR-MILs maintained higher levels of CD27 and lower levels of PD1 and TIM3 compared to CAR-PBLs following antigen-stimulation in both CD4 and CD8 T cells. Conclusions Collectively, our data suggest that CAR-MILsTM have several advantages over CAR-PBLs, including increased cytolytic potential, enhanced polyfunctionality, increased stemness and less exhaustion. Based on these differences and the inherent antitumor properties of MILsTM, we speculate that CAR-MILsTM would be more potent and effective than currently approved CAR-T products derived from PBLs. Disclosures Lutz: WindMIL Therapeutics: Employment, Equity Ownership. Jana:WindMIL Therapeutics: Employment, Equity Ownership. Rudraraju:WindMIL Therapeutics: Employment, Equity Ownership. DeOliveira:WindMIL Therapeutics: Employment, Equity Ownership. Zhou:Isoplexis: Employment, Equity Ownership. Mackay:Isoplexis: Employment, Equity Ownership. Borrello:Aduro: Patents & Royalties: intellectual property on allogeneic MM GVAX; BMS: Consultancy; WindMIL Therapeutics: Equity Ownership, Patents & Royalties, Research Funding; Celgene: Honoraria, Research Funding, Speakers Bureau. Noonan:WindMIL Therapeutics: Employment, Equity Ownership, Patents & Royalties; Aduro: Patents & Royalties: intellectual property on allogeneic MM GVAX.
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Utomo, Supri Wahyudi, Soetarno Joyoatmojo, Sri Jutmini, and Nunuk Suryani. "Improving Higher Order Thinking Skills Through Problem Based Learning with a Scientific Approach." Dinamika Pendidikan 14, no. 1 (2019): 76–86. http://dx.doi.org/10.15294/dp.v14i1.18776.

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This study aims to describe the effectiveness of the problem-based learning model with a scientific approach to improve higher order thinking skills. The type of research used in this study was quasi-experimental with pre-test and post-test group design. The study was conducted by using one control class and one experimental class. The study was conducted on vocational students with a sample of 64 students consisting of 32 students in experimental class and 32 students in control class. The essay test was used as an instrument for retrieving data. Descriptive analysis and t-test were used to do data analysis. The descriptive test results showed that the average score of HOTS in the control class and experimental class had increased. The results of the t-test showed that there was a significant difference in the score of the pre-test and the post-test in the experimental class, whereas the control class had no significant difference. The conclusion of the results of the study shows that there was a difference between the improvement of higher order thinking skills using conventional models and PBLS models. The PBLS model was able to improve students' Higher Order Thinking Skills.
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Tishon, Antoinette, Marianne Manchester, Friedrich Scheiflinger, and Michael B. A. Oldstone. "A model of measles virus–induced immunosuppression: Enhanced susceptibility of neonatal human PBLs." Nature Medicine 2, no. 11 (1996): 1250–54. http://dx.doi.org/10.1038/nm1196-1250.

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Korin, Yael D., David G. Brooks, Stephen Brown, Andrew Korotzer, and Jerome A. Zack. "Effects of Prostratin on T-Cell Activation and Human Immunodeficiency Virus Latency." Journal of Virology 76, no. 16 (2002): 8118–23. http://dx.doi.org/10.1128/jvi.76.16.8118-8123.2002.

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ABSTRACT Human immunodeficiency virus (HIV) replication is linked to cellular gene transcription and requires target cell activation. The latent reservoir of HIV-1 in quiescent T cells is thought to be a major obstacle to clearance of infection by highly active antiretroviral therapy (HAART). Thus, identification of agents that can induce expression of latent virus may, in the presence of HAART, allow elimination of the infected cells by the immune response. We previously used the SCID-hu (Thy/Liv) mouse model to establish that activation-inducible HIV can be generated at high frequency during thymopoiesis. Latently infected mature thymocytes can be exported into the periphery, providing an efficient primary cell model to determine cellular activation signals that induce renewed expression of latent virus. Here we characterized the effects of prostratin, a non-tumor-promoting phorbol ester, on primary human peripheral blood lymphocytes (PBLs) and assessed its ability to reactivate latent HIV infection from thymocytes and PBLs in the SCID-hu (Thy/Liv) model. Prostratin stimulation alone did not induce proliferation of quiescent PBLs; however, it could provide a secondary signal in the context of T-cell receptor stimulation or a primary activation signal in the presence of CD28 stimulation to induce T-cell proliferation. While prostratin alone was not sufficient to allow de novo HIV infection, it efficiently reactivated HIV expression from latently infected cells generated in the SCID-hu mouse. Our data indicate that prostratin alone is able to specifically reactivate latent virus in the absence of cellular proliferation, making it an attractive candidate for further study as an adjunctive therapy for the elimination of the latent HIV reservoir.
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McGrath-Spangler, E. L., A. Molod, L. E. Ott, and S. Pawson. "Impact of planetary boundary layer turbulence on model climate and tracer transport." Atmospheric Chemistry and Physics Discussions 14, no. 23 (2014): 31627–74. http://dx.doi.org/10.5194/acpd-14-31627-2014.

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Abstract. Planetary boundary layer (PBL) processes are important for weather, climate, and tracer transport and concentration. One measure of the strength of these processes is the PBL depth. However, no single PBL depth definition exists and several studies have found that the estimated depth can vary substantially based on the definition used. In the Goddard Earth Observing System (GEOS-5) atmospheric general circulation model, the PBL depth is particularly important because it is used to calculate the turbulent length scale that is used in the estimation of turbulent mixing. This study analyzes the impact of using three different PBL depth definitions in this calculation. Two definitions are based on the scalar eddy diffusion coefficient and the third is based on the bulk Richardson number. Over land, the bulk Richardson number definition estimates shallower nocturnal PBLs than the other estimates while over water this definition generally produces deeper PBLs. The near surface wind velocity, temperature, and specific humidity responses to the change in turbulence are spatially and temporally heterogeneous, resulting in changes to tracer transport and concentrations. Near surface wind speed increases in the bulk Richardson number experiment cause Saharan dust increases on the order of 1 × 10−4 kg m−2 downwind over the Atlantic Ocean. Carbon monoxide (CO) surface concentrations are modified over Africa during boreal summer, producing differences on the order of 20 ppb, due to the model's treatment of emissions from biomass burning. While differences in carbon dioxide (CO2) are small in the time mean, instantaneous differences are on the order of 10 ppm and these are especially prevalent at high latitude during boreal winter. Understanding the sensitivity of trace gas and aerosol concentration estimates to PBL depth is important for studies seeking to calculate surface fluxes based on near-surface concentrations and to studies projecting future concentrations.
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McGrath-Spangler, E. L., A. Molod, L. E. Ott, and S. Pawson. "Impact of planetary boundary layer turbulence on model climate and tracer transport." Atmospheric Chemistry and Physics 15, no. 13 (2015): 7269–86. http://dx.doi.org/10.5194/acp-15-7269-2015.

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Abstract. Planetary boundary layer (PBL) processes are important for weather, climate, and tracer transport and concentration. One measure of the strength of these processes is the PBL depth. However, no single PBL depth definition exists and several studies have found that the estimated depth can vary substantially based on the definition used. In the Goddard Earth Observing System (GEOS-5) atmospheric general circulation model, the PBL depth is particularly important because it is used to calculate the turbulent length scale that is used in the estimation of turbulent mixing. This study analyzes the impact of using three different PBL depth definitions in this calculation. Two definitions are based on the scalar eddy diffusion coefficient and the third is based on the bulk Richardson number. Over land, the bulk Richardson number definition estimates shallower nocturnal PBLs than the other estimates while over water this definition generally produces deeper PBLs. The near-surface wind velocity, temperature, and specific humidity responses to the change in turbulence are spatially and temporally heterogeneous, resulting in changes to tracer transport and concentrations. Near-surface wind speed increases in the bulk Richardson number experiment cause Saharan dust increases on the order of 1 × 10−4 kg m−2 downwind over the Atlantic Ocean. Carbon monoxide (CO) surface concentrations are modified over Africa during boreal summer, producing differences on the order of 20 ppb, due to the model's treatment of emissions from biomass burning. While differences in carbon dioxide (CO2) are small in the time mean, instantaneous differences are on the order of 10 ppm and these are especially prevalent at high latitude during boreal winter. Understanding the sensitivity of trace gas and aerosol concentration estimates to PBL depth is important for studies seeking to calculate surface fluxes based on near-surface concentrations and for studies projecting future concentrations.
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Massart, C., J. Gibassier, M. L. Raoul, et al. "Action of peripheral or intrathyroidal lymphocytes on autologous thyrocytes cultured in follicles in collagen gel." Journal of Molecular Endocrinology 18, no. 2 (1997): 137–45. http://dx.doi.org/10.1677/jme.0.0180137.

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ABSTRACT We have studied the action of peripheral blood lymphocytes (PBLs) and intrathyroidal lymphocytes (ITLs) on the biochemical and hormonal metabolism of autologous thyrocytes cultured in follicles in a collagen gel. The production of tumour necrosis factor α (TNF-α) in culture was also measured. Thyroid tissues and lymphocytes were obtained from ten patients with Graves' disease and from five control subjects. Lymphocyte-induced cytotoxicity was evaluated in autologous thyrocytes cultured in a collagen gel by several tests: neutral red uptake, lactate dehydrogenase activity and glutathione level. Hormonal metabolism was assessed by evaluating tri-iodothyronine (T3) and total cAMP production under TSH stimulation. TNF-α levels were measured in supernatants after 5 days of coculture. PBLs altered biochemical metabolism, T3 synthesis and cAMP production in autologous thyroid follicles. These inhibitions were greater than those obtained with ITLs. No difference was seen between cells obtained from patients with Graves' disease and those from normal subjects. TNF-α levels secreted by PBLs were higher than those secreted by ITLs. The concentrations of this cytokine decreased in coculture. Significant correlations were observed between the decrease in biochemical and hormonal parameters and TNF-α levels. Exogenous TNF-α and high doses of interferon γ inhibited follicle metabolism, especially hormone secretion. In conclusion, thyrocytes cultured in follicles provide a more sensitive model than monolayer cultures for analysis of lymphocyte-induced interactions. Lymphocytes gradually inhibit the biochemical and hormonal metabolism of autologous thyroid follicles depending on the isolation method. These alterations may be particularly attributed to TNF-α secreted by lymphocytes. The cytokine-induced inhibition of thyroid hormonal function apparently involves the adenylate cyclase system.
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Dissertations / Theses on the topic "PBLs model"

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Kpemlie, Emmanuel Kwashi. "Assimilation variationnelle de données de télédétection dans des modèles de fonctionnement des couverts végétaux et du paysage agricole." Phd thesis, Université d'Avignon, 2009. http://tel.archives-ouvertes.fr/tel-00555416.

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La connaissance du microclimat et de l'évapotranspiration ou flux de chaleur latente qui représente la consommation réelle en eau de la culture à l'échelle des parcelles agricoles est une donnée importante pour comprendre le développement des cultures. La plupart des modèles permettant d'estimer l'évapotranspiration sont utilisés sur des surfaces homogènes sans tenir compte des interactions surface - atmosphère et de la variabilité spatiale du domaine agricole. Nous avons utilisé un modèle de couche limite atmosphérique afin de prendre en compte ces interactions. Une approche dite " patchée " permet d'introduire la variabilité spatiale des surfaces dans le modèle à partir des diverses proportions et des caractéristiques des principaux couverts végétaux qui composent le paysage. Une méthode d'assimilation variationnelle a été implémentée afin d'estimer certains paramètres du modèle difficile à connaître précisément. La méthode est basée sur le calcul de l'adjoint du modèle et utilise une température de surface observée par télédétection. L'approche développée est comparée à des approches plus simples considérant chaque type de surface indépendamment, mettant en évidence le rôle de la prise en compte de la variabilité spatiale de la surface sur la simulation du microclimat et des flux de surface
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Ježková, Zuzana. "Komplexní zhodnocení výkonnosti společnosti PBS Industry, a.s." Master's thesis, Vysoká škola ekonomická v Praze, 2010. http://www.nusl.cz/ntk/nusl-76097.

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Comprehensive evaluation of performance analysis of PBS INDUSTRY, a.s. When evaluating the performance of PBS INDUSTRY, a.s. the financial statements of the company for the period of 2005 -- 2008 are used. Performance evaluation is done through traditional methods of financial analysis and modern methods of economic added value. The interpretation of analytical results and recommendations was made.
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Gassner, Lina. "Developing metacognitive awareness - a modified model of a PBL-tutorial." Thesis, Malmö högskola, Odontologiska fakulteten (OD), 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-19779.

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In order for students to become good self-directed learners, an awareness of one’s own learning process and studying strategies is essential. The aim of this paper is to describe a project –and the results of it - where a modified model of a problem-based learning (PBL) tutorial is used, a project launched to develop students’ metacognitive awareness and improve the quality of their tutorials. Dental hygiene students and their tutors at the faculty of Odontology, Malmö University participated in the project which meant that the students worked independently during the first PBL-session with the tutor only paying a few short visits to the group. At these visits, the students presented their problems, hypotheses and objectives with the purpose to create an opportunity of primarily reviewing and reflecting but also getting feed-back from the tutor. The tutor was present throughout the second PBL-session. This model was alternated with and compared to the traditional “Malmö model” in which the tutor participates throughout both PBL-sessions. The project was evaluated through interviews. A Metacognitive Awareness Inventory (MAI) was filled in before and after the project. Results for the MAI show a significant increase in metacognitive awareness. In the interviews, students state that they participated in the PBL-session to a greater extent and had more spontaneous discussions without the tutor, but also that they felt a lack of security and sometimes interrupted by the visits from the tutor.
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Krankowski, Edward. "School Psychology Service Provisions Within a Public Health Model." Thesis, University of Oregon, 2013. http://hdl.handle.net/1794/12963.

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The purpose of this study was to explore specific activities school psychologists performed related to both testing and placing within a medical model and prevention within a public health model. Spurred by landmark legal mandates, school districts are moving toward preventative practice within a framework consistent with tenets of a public health model or Response to Intervention (RtI) framework. These activities are counter to traditional test-and-place activities performed by school psychologists associated with a medical model of service delivery. School psychologists assigned to 41 elementary schools in the northwest corner of Oregon completed a survey that included activities associated with testing-and-placing students typified by a medical model and those activities akin to a public health model. All schools participating in this study implemented Positive Behavioral Interventions and Supports (PBIS). PBIS is a widely implemented evidence-based practice in education that emphasizes prevention, and is a reflection of RtI or the public health model. Although PBIS was a common denominator across all schools, there were differences in overall implementation effectiveness as measured by the School-wide Evaluation Tool (SET). This study investigated the degree to which activities performed by school psychologists impacted PBIS implementation in their buildings. School psychologists estimated the frequency devoted to these activities. Frequency served as a proxy for priority and also defined the service models that guided their practices. In addition to this descriptive statistical analysis, inferential statistics were used to measure the correlation between the School Psychologist Survey, the SET-General Index scores, and the SET-Behavior Expectations Index scores. A multiple-regression analysis was also conducted to determine which variable (i.e., SET-General Index or SET-Behavior Expectations Index) was the best predictor of outcome data from the School Psychologist Survey. These data were also entered into scatterplots to provide interpretations of meaningful statistical significance for an in-depth analysis of the School Psychologist Survey, SET-General Index, and SET-Behavior Index scores. This study is important because it potentially provides school psychologists with specific preventative activities they can perform within a public health model of service delivery to make contributions for improving the overall school environment for students.
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VIDAL, Tiago Carvalho. "PBL-tutor Canvas: uma ferramenta de planejamento do ensino de computação na abordagem PBL baseada no modelo backward design." Universidade Federal de Pernambuco, 2016. https://repositorio.ufpe.br/handle/123456789/26247.

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LIMA, Simone Cristiane dos Santos, também é conhecida em citações bibliográficas por: SANTOS, Simone Cristiane dos, conforme citações em publicações.<br>Submitted by Pedro Barros (pedro.silvabarros@ufpe.br) on 2018-08-22T19:19:24Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Tiago Carvalho Vidal.pdf: 3555975 bytes, checksum: f866151ed9081dbb0d59fe392d508b71 (MD5)<br>Rejected by Alice Araujo (alice.caraujo@ufpe.br), reason: on 2018-08-29T21:56:12Z (GMT)<br>Submitted by Pedro Barros (pedro.silvabarros@ufpe.br) on 2018-08-29T22:08:47Z No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Tiago Carvalho Vidal.pdf: 3555975 bytes, checksum: f866151ed9081dbb0d59fe392d508b71 (MD5)<br>Approved for entry into archive by Alice Araujo (alice.caraujo@ufpe.br) on 2018-09-05T20:17:25Z (GMT) No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Tiago Carvalho Vidal.pdf: 3555975 bytes, checksum: f866151ed9081dbb0d59fe392d508b71 (MD5)<br>Made available in DSpace on 2018-09-05T20:17:25Z (GMT). No. of bitstreams: 2 license_rdf: 811 bytes, checksum: e39d27027a6cc9cb039ad269a5db8e34 (MD5) DISSERTAÇÃO Tiago Carvalho Vidal.pdf: 3555975 bytes, checksum: f866151ed9081dbb0d59fe392d508b71 (MD5) Previous issue date: 2016-02-12<br>O método Problem-Based Learning ou PBL (termo usado na língua inglesa) surge como alternativa para tratar o desenvolvimento de competências e habilidades para resolução de problemas, requeridas pelo mercado de trabalho atual. No entanto, estudos sinalizam que devido à subjetividade dos conceitos somada à ausência de guias e instrumentos eficazes para sua aplicação, o planejamento de ensino de PBL fica comprometido e dependente da capacidade do docente. Os trabalhos relacionados apontam a existência de diretrizes para planejamento de infraestrutura de suporte para os cursos/disciplinas em PBL, no entanto, observa-se uma lacuna de instrumentos que contemplem o planejamento de ensino propriamente dito, considerando o exercício dos princípios PBL durante o processo PBL. O presente trabalho tem como objetivo propor uma abordagem de planejamento de ensino PBL apoiado pelo Backward Design Model que conduzirá o docente a estruturar o planejamento de modo a contemplar processos e princípios PBL, maximizando assim, a aderência das atividades propostas à cultura PBL. O método de avaliação utilizado consistiu na aplicação de questionários com docentes que possuem conhecimento/experiência em PBL e que lecionam em instituições de ensino superior, no domínio de computação. Nesse contexto, os resultados obtidos sinalizam aceitação à estrutura proposta, bem como indicam que a abordagem auxilia no processo de planejamento de ensino PBL, contribuindo para maximizar a maturidade em PBL, devido sua orientação aos princípios PBL.<br>The Problem-Based Learning method or PBL (term used in English) is an alternative to manage the development of skills and abilities to solve problems, required by the current labor market. However, studies indicate that due to the subjectivity of concepts and also due to the absence of guidelines and effective instruments for its implementation, the PBL teaching planning is compromised and dependent on the teacher's ability. Related studies indicate the existence of guidelines to support infrastructure planning for the courses / subjects in PBL, however, there is a lack of instruments dealing with the educational planning itself, considering the exercise of PBL principles in the process PBL. This paper aims to propose a PBL educational planning approach supported by the Backward Design Model that will lead teachers to structure their planning in order to comply with PBL processes and principles, maximizing the adherence of proposed activities to the PBL culture. The evaluation method used consisted of questionnaires with teachers who have knowledge / experience in PBL and who teach in higher education institutions in the computing domain. In this context, the results indicate acceptance to the proposed structure as well as indicate the approach assists in PBL educational planning process, helping to maximize maturity in PBL once it is directly driven by the PBL principles.
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Fraczek, Margo. "Perpetuating a Culture of White Behavior: The Experiences of Non-Native Speaking Hispanic Students in a PBIS School." Thesis, Boston College, 2010. http://hdl.handle.net/2345/bc-ir:104465.

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Thesis advisor: Elizabeth Twomey<br>This phenomenological study investigated the effects of a Positive Behavior Intervention and Support (PBIS) Program on non-native speaking Hispanic students in a public middle school. The purpose of the study is to discover whether the PBIS program alleviates, intensifies or does not change the degree of bias towards minority students currently in existence through traditional discipline models. It also intends to discover whether the experience of the Hispanic students is similar to the intent of the program as determined by the implementing staff. Finally, this study will investigate whether a program that explicitly teaches values reflects the white, middle class backgrounds of the staff and whether this is detrimental to the primarily minority student population at the school. An outside researcher who had previously spent time at the school site as a principal intern conducted this qualitative, phenomenological study. The researcher used the following data collection tools: individual semi-formal interviews, focus group discussions, observations, and document analysis. The research occurred over approximately six weeks. The study concluded that the values taught through PBIS were designed to bring the students into the teachers' world, a world considered superior to the students as well as universal. This indicated that the teachers held a deficit model of culture towards the students' culture. Another finding indicated a need on the part of the staff to be aware of the students' relationship with their family as they implement any discipline program, especially one that explicitly teaches values. Finally, the study found a need for teachers to build positive relationships with all students, especially those with disciplinary issues. It was through positive relationships with the students deemed "problems" by the school and their parents that the teachers were able to reduce problem behaviors<br>Thesis (PhD) — Boston College, 2010<br>Submitted to: Boston College. Lynch School of Education<br>Discipline: Educational Leadership and Higher Education
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Washington, Dione. "Learning Models, Personality Traits, and Job Satisfaction in Forensic Psychology Practitioners." ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/7771.

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Forensic psychology is a distinct specialization requiring practitioners to approach problems differently than in other psychological specialties. While the use of problem-based learning in the medical field is well-researched, there is a lack of literature regarding its use in forensic psychology. This quantitative survey-based study was designed to investigate the relationship between learning models and personality traits and job satisfaction in forensic psychologists. In the current study, an adaption of Vygotsky’s constructivist zone of proximal development theory and Holland’s theory of career choice were applied to forensic psychology instruction to assess the degree to which personality and learning models interrelate among forensic psychologists. Overall, the sample population of 49 forensic psychology professionals experienced moderate to high levels of job satisfaction, irrespective of personality. No statistical significance was found with regard to learning model, personality, and job satisfaction. While not statistically significant, the findings do highlight a personality typology that differed from the overarching psychology profession. Holland’s theory categorized individuals in the psychology/psychologist profession as social and artistic. In the current study approximately 37% identified as investigative, while only 4% identified as artistic. It may be beneficial to expand the inclusion criteria to international participants to provide additional statistical analysis with a larger data set. Positive social change may result from an increased awareness of which personality types are better aligned to the forensic psychology profession.
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Ramos, Eliane Santiago. "Especificação e verificação formal de um modelo de STI-PBL por redes de PETRI coloridas." Instituto Tecnológico de Aeronáutica, 2009. http://www.bd.bibl.ita.br/tde_busca/arquivo.php?codArquivo=2229.

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Apresenta-se neste trabalho uma abordagem de Redes de Petri Coloridas para especificação e verificação formal de um modelo de Sistema Tutor Inteligente que utiliza a Aprendizagem Baseada em Problemas como estratégia pedagógica. A especificação e a verificação formal permitem verificar se as funcionalidades planejadas do modelo pedagógico serão realizadas, antes da etapa de implementação do sistema. Adicionalmente, o mecanismo de inferência avalia as informações coletadas nas atividades de interação do aprendiz no processo de solução de problemas e infere, por simulação de Cadeias de Markov Monte Carlo, a probabilidade de o aprendiz resolver um problema, com o propósito de capacitar o sistema à tomada de decisões. Experimentos iniciais indicam consistência geral e benefícios da proposta.
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Im, Sothearith. "A Public Service Broadcasting Model for Developing Countries: The Case of Cambodia." Ohio University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1304521470.

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Kulikowski, Laura L. "An Evaluation of the Prevent-Teach-Reinforce (PTR) Model in a Community Preschool Setting." Scholar Commons, 2010. http://scholarcommons.usf.edu/etd/3643.

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This study evaluated the use of the Prevent-Teach-Reinforce (PTR) model with two four-year-old children in a community preschool classroom. A multiple baseline design across activities was used to assess the teacher implementation of the behavior intervention strategies developed during the PTR team process and the changes in child problem behavior and engagement. Additional measures associated with the outcomes, such as researcher procedural integrity and social validity were assessed. The results suggest that the team of teachers were able to implement the PTR intervention with fidelity, which resulted in a decrease in the children’s problem behavior and an increase in their engagement. The PTR process was deemed feasible and acceptable by the teaching staff, and that the child behavioral outcomes were evaluated as acceptable by naïve observers.
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Books on the topic "PBLs model"

1

Degand, Liesbeth, Bert Cornillie, and Paola Pietrandrea, eds. Discourse Markers and Modal Particles. John Benjamins Publishing Company, 2013. http://dx.doi.org/10.1075/pbns.234.

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Anette Kolmos; Flemming K. Fink; Lone Krogh (eds.). The Aalborg PBL Model: Progress, Diversity and Challenges. Aalborg University Press, 2005.

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PBIS Tier One Handbook: A Practical Approach to Implementing the Champion Model. Corwin Press, 2015.

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A, Taylor Peter, Wyngaard John C, and European Centre for Medium Range Weather Forecasts., eds. PBL model evaluation workshop: European Centre for Medium-range Forecasts, 14-15 August 1989, Reading, U.K. World Meteorological Organization, 1990.

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Report of the OECD/UNEP Workshop on the Use of Multimedia Models for Estimating Overall Environmental Persistence and Long Range Transport in the Context of PBTS/POPS Assessment. OECD, 2002. http://dx.doi.org/10.1787/9789264078505-en.

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Book chapters on the topic "PBLs model"

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Johnson, Bart, and Ron Ulseth. "Iron Range Engineering Model." In PBL in Engineering Education. SensePublishers, 2017. http://dx.doi.org/10.1007/978-94-6300-905-8_4.

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Aijmer, Karin. "Analyzing modal adverbs as modal particles and discourse markers." In Discourse Markers and Modal Particles. John Benjamins Publishing Company, 2013. http://dx.doi.org/10.1075/pbns.234.04aij.

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Degand, Liesbeth, Bert Cornillie, and Paola Pietrandrea. "Modal particles and discourse markers: Two sides of the same coin?" In Discourse Markers and Modal Particles. John Benjamins Publishing Company, 2013. http://dx.doi.org/10.1075/pbns.234.01deg.

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Diewald, Gabriele. "“Same same but different” – Modal particles, discourse markers and the art (and purpose) of categorization." In Discourse Markers and Modal Particles. John Benjamins Publishing Company, 2013. http://dx.doi.org/10.1075/pbns.234.02die.

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Fischer, Kerstin, and Maria Alm. "A radical construction grammar perspective on the modal particle-discourse particle distinction." In Discourse Markers and Modal Particles. John Benjamins Publishing Company, 2013. http://dx.doi.org/10.1075/pbns.234.03fis.

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Valdmets, Annika. "Modal particles, discourse markers, and adverbs with lt-suffix in Estonian." In Discourse Markers and Modal Particles. John Benjamins Publishing Company, 2013. http://dx.doi.org/10.1075/pbns.234.05val.

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Schoonjans, Steven. "Modal particles: Problems in defining a category." In Discourse Markers and Modal Particles. John Benjamins Publishing Company, 2013. http://dx.doi.org/10.1075/pbns.234.06sch.

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Squartini, Mario. "From TAM to discourse." In Discourse Markers and Modal Particles. John Benjamins Publishing Company, 2013. http://dx.doi.org/10.1075/pbns.234.07squ.

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Cuenca, Maria Josep. "The fuzzy boundaries between discourse marking and modal marking." In Discourse Markers and Modal Particles. John Benjamins Publishing Company, 2013. http://dx.doi.org/10.1075/pbns.234.08cue.

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Izutsu, Katsunobu, and Mitsuko Narita Izutsu. "From discourse markers to modal/final particles." In Discourse Markers and Modal Particles. John Benjamins Publishing Company, 2013. http://dx.doi.org/10.1075/pbns.234.09izu.

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Conference papers on the topic "PBLs model"

1

Polezhayeva, Antonina, and Antonina Polezhayeva. "NUMERICAL MODELING OF POLAR LOWS OVER THE BARENTS SEA: IMPACT OF WRF PARAMETRIZATIONS ON THE QUALITY OF FORECAST." In Managing risks to coastal regions and communities in a changing world. Academus Publishing, 2017. http://dx.doi.org/10.21610/conferencearticle_58b43155456a5.

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Polar lows are generally characterized by severe weather in the form of strong winds, showers and occasionally heavy snow, which have sometimes resulted in the loss of life, especially at sea. Numerical simulations with mesoscale atmospheric models is a good alternative to investigate polar low phenomenon, because they produce temporally and spatially regular-spaced fields of atmospheric variables with high resolution. To describe the evolution of atmospheric processes the Advanced Weather Research and Forecasting (WRF-ARW) model was used. The principal objectives of this study were 1) the understanding of mesoscale WRF model and adapting the model for the Barents Sea region; 2) to conduct numerical experiments using WRF model with different Planetary Boundary Layer parameterization (PBLs) schemes and investigate the impact of each scheme on the quality of forecast; and 3) the investigation of the capability of WRF model to successfully simulate evolution of polar lows. The impact on the quality of forecast was investigated. The results of the study, obtained by numerical modeling of polar mesoscale low over the Barents Sea. One polar low, near Spitsbergen, from 24 of March to 26 of March 2014 were targeted. The results of numerical experiments showed that each of Planetary Boundary Layer parameterization scheme isn't successful for simulation of polar low.
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Polezhayeva, Antonina, and Antonina Polezhayeva. "NUMERICAL MODELING OF POLAR LOWS OVER THE BARENTS SEA: IMPACT OF WRF PARAMETRIZATIONS ON THE QUALITY OF FORECAST." In Managing risks to coastal regions and communities in a changing world. Academus Publishing, 2017. http://dx.doi.org/10.31519/conferencearticle_5b1b9387834ac4.45240165.

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Polar lows are generally characterized by severe weather in the form of strong winds, showers and occasionally heavy snow, which have sometimes resulted in the loss of life, especially at sea. Numerical simulations with mesoscale atmospheric models is a good alternative to investigate polar low phenomenon, because they produce temporally and spatially regular-spaced fields of atmospheric variables with high resolution. To describe the evolution of atmospheric processes the Advanced Weather Research and Forecasting (WRF-ARW) model was used. The principal objectives of this study were 1) the understanding of mesoscale WRF model and adapting the model for the Barents Sea region; 2) to conduct numerical experiments using WRF model with different Planetary Boundary Layer parameterization (PBLs) schemes and investigate the impact of each scheme on the quality of forecast; and 3) the investigation of the capability of WRF model to successfully simulate evolution of polar lows. The impact on the quality of forecast was investigated. The results of the study, obtained by numerical modeling of polar mesoscale low over the Barents Sea. One polar low, near Spitsbergen, from 24 of March to 26 of March 2014 were targeted. The results of numerical experiments showed that each of Planetary Boundary Layer parameterization scheme isn't successful for simulation of polar low.
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3

Nakamori, Riko, Yuki Kageyama, and Nozomu Baba. "Experimental Study on Behavior of Shear Connectors Embedded in Steel-Reinforced Concrete Joints." In 12th international conference on ‘Advances in Steel-Concrete Composite Structures’ - ASCCS 2018. Universitat Politècnica València, 2018. http://dx.doi.org/10.4995/asccs2018.2018.7124.

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This paper presents an experimental study on the behavior of shear connectors embedded in steel-reinforced concrete joints. In steel-reinforced concrete joints, the shear connectors are commonly used to transfer longitudinal shear forces across the steel-concrete interface. Further, in Japan, some studies in recently have also been undertaken to apply perfobond rib shear connector (PBL), which is a type of shear connectors developed in civil engineering, to the steel-reinforced concrete joints in building structures. To clarify the influence of the arrangement methods of headed studs and PBLs to reinforced concrete member on the joints, T-shaped subassembrages were tested under the monotonic tensil loading.This experiment is constituted of the following; Exp. I: Bond strength across the steel-concrete interface. Exp. II: Arrangement methods of these shear connectors to reinforced concrete member. The following can be drawn from the test results 1) The experimental values of the average maximum and residual bond strength are 0.230-0.280 and 0.15-0.18 N/mm2, respectively. 2) When the distance of between the upper surface of the reinforced concrete member from the first layer for headed studs are small, the failure mode of the specimens is similar to a concrete-cone type failure. 3) In case that the total number of headed studs or the hole provided to PBL is the same, the maximum load of the specimen with the parallel arrangement is larger than that of when shear connecters are vertically arranged. 4) The shear strength of headed studs in the joints embedded the steel member in the reinforced concrete member is estimated by superposing the average residual bond strength across the steel-concrete interface.
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Sato, Yoshiki, Atsuo Hazeyama, Shoichi Nakamura, and Youzou Miyadera. "Development of a PBL Workflow Model and Classification of PBL Themes." In 2019 IEEE 11th International Conference on Engineering Education (ICEED). IEEE, 2019. http://dx.doi.org/10.1109/iceed47294.2019.8994921.

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Zheng, Wei. "PBL Teaching Model in College English Learning." In 2016 2nd International Conference on Economics, Management Engineering and Education Technology (ICEMEET 2016). Atlantis Press, 2017. http://dx.doi.org/10.2991/icemeet-16.2017.53.

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Wang, Hechun, Xiaohua Jia, Fu Jin, and Yupu Chen. "Research on PBGS Teaching Model under the Activities Theory." In 2017 3rd International Conference on Social Science and Higher Education. Atlantis Press, 2017. http://dx.doi.org/10.2991/icsshe-17.2017.67.

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Guo, Jidong, and Xueqing Li. "Model for Distributed Learning Space Based on PBL." In 2008 International Symposium on Knowledge Acquisition and Modeling (KAM). IEEE, 2008. http://dx.doi.org/10.1109/kam.2008.49.

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Lu, Yanglong, and Yan Wang. "An Improvement of Physics Based Compressive Sensing With Domain Decomposition to Monitor Temperature in Fused Filament Fabrication Process." In ASME 2019 14th International Manufacturing Science and Engineering Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/msec2019-2899.

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Abstract Sensors in manufacturing play an important role in monitoring and improving the quality of products. However, the rising cost of sensing subsystems and the bandwidth limitation of data transmission are challenges in modern manufacturing systems, which rely on a large number of sensors. Recently, a physics based compressive sensing (PBCS) approach was proposed to monitor manufacturing processes with reduced number of sensors and amount of collected data. PBCS significantly improves the compression ratio from classical compressed sensing by incorporating the knowledge of physical phenomena in specific applications. In this paper, a modified orthogonal matching pursuit (OMP) recovery algorithm, called constrained OMP, is developed for PBCS when coherence exists between the measurement matrix and basis matrix. The efficiency of PBCS recovery is also improved by introducing a domain decomposition approach, which can reduce the size of model matrices, such as the conduction matrix and mass matrix in the transient heat transfer application. The improved PBCS with the domain decomposition method is used to monitor the temperature distribution in the cooling process and real-time printing process of fused filament fabrication.
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dos Santos, Simone C., Caliane O. Figueredo, and Fernando Wanderley. "PBL-Test: A model to evaluate the maturity of teaching processes in a PBL approach." In 2013 IEEE Frontiers in Education Conference (FIE). IEEE, 2013. http://dx.doi.org/10.1109/fie.2013.6684894.

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Zhibin Hu, Xiaobo Zhou, and Xiaohong Yan. "A way of reconstructing the continuous-time dynamical model of PBNs." In 2005 International Symposium on Intelligent Signal Processing and Communication Systems. IEEE, 2005. http://dx.doi.org/10.1109/ispacs.2005.1595448.

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