Relevant bibliographies by topics / PCD

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'PCD'

Author: Grafiati
Published: 4 June 2021
Last updated: 10 March 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'PCD.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "PCD"

1

Al-Sehemi, Abdullah G., Tarek M. El-Gogary, Karl Peter Wolschann, and Gottfried Koehler. "Structure and Stability of Chemically Modified DNA Bases: Quantum Chemical Calculations on 16 Isomers of Diphosphocytosine." ISRN Physical Chemistry 2013 (February 25, 2013): 1–10. http://dx.doi.org/10.1155/2013/146401.

Full text
Abstract:
We studied for the first time 16 tautomers/rotamers of diphosphocytosine by four computational methods. Some of these tautomers/rotamers are isoenergetic although they have different structures. High-level electron correlation MP2 and MP4(SDQ) ab initio methods and density functional methods employing a B3LYP and the new M06-2X functional were used to study the structure and relative stability of 16 tautomers/rotamers of diphosphocytosine. The dienol tautomers of diphosphocytosine are shown to be much more stable than the keto-enol and diketo forms. The tautomers/rotamers stability could be ranked as PC3 = PC12 < PC2 = PC11 < PC1 < PC10 < PC8 < PC9 < PC15 < PC16 < PC6 ~ PC7 < PC13 < PC4 ~ PC14 < PC5. This stability order was discussed in the light of stereo and electronic factors. Solvation effect has been modeled in a high dielectric solvent, water using the polarized continuum model (PCM). Consideration of the solvent causes some reordering of the relative stability of diphosphocytosine tautomers: PC3 ~ PC12 ~ PC2 ~ PC11 < PC1 < PC10 < PC8 < PC9 < PC15 ~ PC16 < PC13 < PC6 ~ PC7 ~ PC14 < PC4 ~ PC5.
APA, Harvard, Vancouver, ISO, and other styles
2

Gibson, Sigrid, and Margaret Ashwell. "Dietary patterns among British adults: compatibility with dietary guidelines for salt/sodium, fat, saturated fat and sugars." Public Health Nutrition 14, no. 8 (May 6, 2011): 1323–36. http://dx.doi.org/10.1017/s1368980011000875.

Full text
Abstract:
AbstractObjectiveTo examine dietary patterns among British adults, associations with Na and macronutrient intakes, and implications for dietary advice.DesignPrincipal component analysis of 7 d weighed dietary records.SubjectsAdults aged 19–64 years (n 1724).SettingNational Diet and Nutrition Survey (2000/2001).ResultsHigh Na intake was associated with more energy-dense diets, higher in fat and SFA (percentage of energy) but lower in non-milk extrinsic sugars (NMES). Eight patterns (PC1 to PC8) explained 40 % of the total variance in food intakes. Three patterns – PC3 (high loadings on bread, fats and cheese), PC2 (meat products, eggs and chips) and PC7 (red meat, sauces and alcohol) – were associated with high Na intake. Of these, PC3 correlated with high Na density and Na:K ratio, while PC2 correlated with fat. By contrast, three patterns – ‘health-conscious’ (PC1; vegetables, fruit, fruit juice, fish), ‘breakfast cereals and milk’ (PC6) and ‘chicken and rice’ (PC8) – were associated with modest Na intake, lower Na density and lower fat and SFA. PC2 was positively correlated, and PC1 was negatively correlated, with adding salt to food. Other patterns were ‘tea/coffee and cakes’ (PC4; associated with high SFA and NMES) and ‘soft drinks and snacks’ (PC5; associated with high NMES but not fat or SFA). The dietary patterns of males and females differed slightly.ConclusionsDietary patterns PC1, PC6, PC8 (vegetables, fruit, fish, milk, breakfast cereals, poultry) were broadly compatible with guidelines for salt, fat, SFA and NMES. However, other patterns tended to be high in either salt or NMES.
APA, Harvard, Vancouver, ISO, and other styles
3

Jensen, Matt, Trent Stellingwerff, Courtney Pollock, James Wakeling, and Marc Klimstra. "Can Principal Component Analysis Be Used to Explore the Relationship of Rowing Kinematics and Force Production in Elite Rowers during a Step Test? A Pilot Study." Machine Learning and Knowledge Extraction 5, no. 1 (February 17, 2023): 237–51. http://dx.doi.org/10.3390/make5010015.

Full text
Abstract:
Investigating the relationship between the movement patterns of multiple limb segments during the rowing stroke on the resulting force production in elite rowers can provide foundational insight into optimal technique. It can also highlight potential mechanisms of injury and performance improvement. The purpose of this study was to conduct a kinematic analysis of the rowing stroke together with force production during a step test in elite national-team heavyweight men to evaluate the fundamental patterns that contribute to expert performance. Twelve elite heavyweight male rowers performed a step test on a row-perfect sliding ergometer [5 × 1 min with 1 min rest at set stroke rates (20, 24, 28, 32, 36)]. Joint angle displacement and velocity of the hip, knee and elbow were measured with electrogoniometers, and force was measured with a tension/compression force transducer in line with the handle. To explore interactions between kinematic patterns and stroke performance variables, joint angular velocities of the hip, knee and elbow were entered into principal component analysis (PCA) and separate ANCOVAs were run for each performance variable (peak force, impulse, split time) with dependent variables, and the kinematic loading scores (Kpc,ls) as covariates with athlete/stroke rate as fixed factors. The results suggested that rowers’ kinematic patterns respond differently across varying stroke rates. The first seven PCs accounted for 79.5% (PC1 [26.4%], PC2 [14.6%], PC3 [11.3%], PC4 [8.4%], PC5 [7.5%], PC6 [6.5%], PC7 [4.8%]) of the variances in the signal. The PCs contributing significantly (p ≤ 0.05) to performance metrics based on PC loading scores from an ANCOVA were (PC1, PC2, PC6) for split time, (PC3, PC4, PC5, PC6) for impulse, and (PC1, PC6, PC7) for peak force. The significant PCs for each performance measure were used to reconstruct the kinematic patterns for split time, impulse and peak force separately. Overall, PCA was able to differentiate between rowers and stroke rates, and revealed features of the rowing-stroke technique correlated with measures of performance that may highlight meaningful technique-optimization strategies. PCA could be used to provide insight into differences in kinematic strategies that could result in suboptimal performance, potential asymmetries or to determine how well a desired technique change has been accomplished by group and/or individual athletes.
APA, Harvard, Vancouver, ISO, and other styles
4

Meeks, M. "PCD or not PCD." Archives of Disease in Childhood 88, no. 5 (May 1, 2003): 460—a—460. http://dx.doi.org/10.1136/adc.88.5.460-a.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Bijarania, Subhash, Anil Pandey, Mainak Barman, Monika Shahani, and Gharsi Ram. "Assesment of divergence among soybean [Glycine max (L.) Merrill] genotypes based on phenological and physiological traits." Environment Conservation Journal 23, no. 1&2 (February 11, 2022): 72–82. http://dx.doi.org/10.36953/ecj.021808-2117.

Full text
Abstract:
A study was conducted to understand genetic divergence in Randomized complete block design accommodating 30 soybean [Glycine max (L.) Merrill] genotypes randomly in three replications. These genotypes were evaluated for twenty-seven traits: five phenological, nine agro-morphological, eight physiological traits (from field-trial) and five physiological traits (from laboratory experiment) recorded and subjected to PCA (Principal Component Analysis) and cluster analysis. Among all the studied cultivars, significant diversity, as well as analysis of dispersion, was recorded for different agro-morphological characters. D2-statistic (Tocher method) framed (generalized distance-based) nine clusters: largest with eight and five were oligo-genotypic. Harvest index>seed yield per plant>germination relative index>seedling dry weight contributed maximum towards total divergence. From the most divergent clusters, 21 crosses involving cluster v genotypes (PS-1347, RKS-18, PS-1092, NRC-142, VLS-94, NRC-136, and Shalimar Soybean-1) with monogenotypic cluster VII (AMS-2014), VIII (RSC-11-15) and III (RSC-10-71) suggested for future hybridization. Out of eighteen, only eight principal components revealed more than 1.00 eigen value and exhibited about 85.03% variability among the traits studied. The highest variability (25.41%) by PC1 followed by PC2 (15.60%), PC3 (12.35%), PC4 (10.13%), PC5 (7.20%), PC6 (5.43%), PC7 (4.80%) and PC8 (4.11%) for characters under study.
APA, Harvard, Vancouver, ISO, and other styles
6

Alkhasawneh, Mutasem Shabeb. "Software Defect Prediction through Neural Network and Feature Selections." Applied Computational Intelligence and Soft Computing 2022 (September 26, 2022): 1–16. http://dx.doi.org/10.1155/2022/2581832.

Full text
Abstract:
Software failure such as software defect causes billion of dollar loss every year. Software failure also affects billion of people worldwide. Inadequate software testing can cause software failure. To predict the software defect, this study proposed a model consisting of feature selection and classifications. The correlation base method was used for feature selection, and radial base function neural network (RBF) was used for classification. Also, for testing the proposed system, fourteen NASA data sets were used including CM1, JM1, KC1, KC2, KC3, KC4, MC1, MC2, MW1, PC1, PC2, PC3, PC4, and PC5. The data set was divided using the well-known K-cross-validation methods which were performed to divide the data set for training and testing the RBF. The RBF were trained and tested before and after feature selections. Precision, recall, F-measure, and accuracy are four methods used to evaluate the performance of the proposed methods. The precision obtained for the fourteen data sets was CM1, 94.01%; JM1, 85.18%; KC1, 83.24%; KC2, 81.27%; KC3, 79.30%; KC4, 85.29%; MC1, 99.89%; MC2, 73.27%; MW1, 90.90%; PC1, 98.79%; PC2, 100%; PC3, 95.67%; PC4, 95.12%; and PC5, 80.89%. Recall was as follows: CM1, 95.78%; JM1, 87.89%; KC1, 86.24%; KC2, 83.82%; KC3, 82.10%; KC4, 86.28%; MC1, 100%; MC2, 76.67%; MW1, 92.09%; PC1, 99.98%; PC2, 100%; PC3, 96.23%; PC4, 95.17%; and PC5, 81.80%. F-measure was as follows: CM1, 0.95; JM1, 0.87; KC1, 0.83; KC2, 0.82; KC3, 0.85; KC4, 0.86; MC1, 0.99; MC2, 0.76; MW1, 0.95; PC1, 0.99; PC2, 0.99; PC3, 0.97; PC4, 0.95; and PC5, 0.80. The accuracy obtained was as follows: CM1, 93.99%; JM1, 84.87%; KC1, 83.25%; KC2, 79.11%; KC3, 78.25%; KC4, 83.18%; MC1, 99.01%; MC2, 70.18%; MW1, 88.90%; PC1, 98.99%; PC2, 99.80%; PC3, 94.11%; PC4, 94.4%; and PC5, 79.02%. The proposed method results were compared with the result obtained from different methods. The proposed model obtained better results than other methods for data set CM1, KC4, MC1, PC1, PC2, PC3, PC4, and PC5.
APA, Harvard, Vancouver, ISO, and other styles
7

Freyer, C., L. M. Kilpatrick, L. A. Salamonsen, and G. Nie. "Pro-protein convertases (PCs) other than PC6 are not tightly regulated for implantation in the human endometrium." Reproduction 133, no. 6 (June 2007): 1189–97. http://dx.doi.org/10.1530/rep-06-0285.

Full text
Abstract:
Pro-protein convertases (PCs) are a family of serine proteases (furin, PC1/3, PC2, PACE4, PC4, PC5/6, PC7/8) responsible for post-translational processing and activation of inactive precursors of many regulatory proteins. Endometrial PC6 is critical for implantation in mice and for decidualization of human endometrial stromal cells (ESCs). This study investigated the endometrial expression of other PCs during the menstrual cycle and early pregnancy to elucidate potential redundancies. Furin, PC4, PACE4, and PC7 along with PC6 transcripts were detected in total endometrial RNA, whereas PC1 and PC2 transcription levels were negligible. Quantitative RT-PCR demonstrated highest levels of furin mRNA during menstruation and lowest levels during the proliferative phase. Furin protein was immunolocalized in endometrial luminal and glandular epithelia, stromal fibroblasts, endothelia, and leukocytes. PACE4 and PC7 proteins were also immunodetected in endometrial stroma and glands. Total furin, PC7, and PACE4 proteins were constitutive in both stromal and glandular compartments throughout the cycle and during first trimester pregnancy. Furthermore, Furin and PC7 transcription was unaltered during decidualization of ESCsin vitroin contrast to PC6 which is significantly up-regulated during decidualization. Thus, whereas PC6 is tightly regulated during endometrial preparation for implantation, furin, PACE4, and PC7 are constitutively expressed in human endometrium, but must be considered if PC6 is to be targeted for manipulation of fertility.
APA, Harvard, Vancouver, ISO, and other styles
8

Kondi, Ravi, Sonali Kar, and Soumya Surakanti. "Agro-morphological and biochemical characterization and principal component analysis for yield and quality characters in fine-scented rice genotypes." Genetika 54, no. 3 (2022): 1005–21. http://dx.doi.org/10.2298/gensr2203005k.

Full text
Abstract:
Forty-one fine-scented rice genotypes were evaluated for 18 agro-morphological and quality characters for characterization, and 21 quantitative characters were evaluated for principal component analysis in R-studio software. Characterization of agro-morphological traits viz., plant height, days to 50% flowering, panicle length, number of effective tillers per plant, test weight, grain length, grain breadth, grain L: B ratio, kernel length, kernel breadth, kernel dimensions, awns, colour of awns, distribution of awns, and quality traits viz., alkali spreading value, gel consistency, grain aroma, and amylose content showed huge diversity among the genotypes. PCA revealed that PC1 showed the highest amount of variance (32.0%) followed by PC2 (15.7%), PC3 (9.0%), PC4 (8.1%), PC5 (7.8%), PC6 (5.4%) for quantitative characters. Out of 21 principal components, only 6 showed an eigenvalue greater than 1 and contributes about 78.1% total variance Genotypes in PC1 showed higher values for grain L: B ratio and kernel L: B ratio. Similarly, PC2 showed higher variable values for characters like test weight, kernel length, grain length, grain breadth, alkali spreading value, grain yield per plot and amylose content. PC3 for harvest index, panicle length, gel consistency, no. of effective tillers per plant and head rice recovery. PC4 for characters like plant height, kernel breadth and days to 50% flowering. PC5 for characters like kernel elongation ratio, and filled grains per panicle. PC6 for characters like no. of tillers in a square meter and no. of panicles in a square meter. This pre-breeding characterization study may be useful in finding potential genotypes which are having both yield and quality characters which may be useful in breeding for high-yielding varieties with good-quality characters.
APA, Harvard, Vancouver, ISO, and other styles
9

Tsai, M. Y., and James C. Sung. "Dressing Behaviors of PCD Conditioners on CMP Polishing Pads." Advanced Materials Research 76-78 (June 2009): 201–6. http://dx.doi.org/10.4028/www.scientific.net/amr.76-78.201.

Full text
Abstract:
Diamond pad conditioner or dresser can determine the efficiency of chemical mechanical polishing (CMP) processes and the quality of polished wafers. Conventional diamond pad conditioners are made by adhering discrete diamond grits on a flat substrate. The size distribution of diamond grits coupled with the deformation of the substrate often make the tips of diamond grits lying at different heights. Instead of attaching individual diamond grits to a metal substrate, a revolutionary design of pad conditioners is based on carving a structure out of sintered polycrystalline diamond (PCD) matrix. The PCD dresser is manufactured by wire electro discharge machining to form cutting pyramids of a specific size with a designed shape. The dressing characteristics of pad surface textures are studied by comparison with conventional diamond pad conditioner. Experimental results indicate that the PCD dresser can dress asperities of the pad more uniformly than the conventional diamond dresser due to PCD dresser having identically shaped tip and the same height diamond. In addition the cutting rate of PCD dresser for IC1000 pad not only is reduced by about 30% but also it can dress pad more effectively than conventional diamond dresser.
APA, Harvard, Vancouver, ISO, and other styles
10

Ding, Xixia, Linfeng Xiang, Qianwei Wang, Dandan Wang, Pingjun Chang, Zhangliang Li, Yinying Zhao, Feixue Chu, Chao Ma, and Yun-e. Zhao. "Clinical Characteristics and Surgical Safety in Congenital Cataract Eyes with Three Pathological Types of Posterior Capsule Abnormalities." Journal of Ophthalmology 2020 (March 23, 2020): 1–9. http://dx.doi.org/10.1155/2020/6958051.

Full text
Abstract:
Purpose. To observe the clinical characteristics of 3 pathological types of posterior capsule abnormalities (PCAs) in congenital cataracts (CCs) and evaluate the surgical safety in these eyes. Methods. This study involved 239 children (367 eyes) with CC who underwent cataract surgery at the Eye Hospital of Wenzhou Medical University. All surgery videos were collected for detailed reviews. Intraoperative and postoperative complications (within 3 months) were all recorded. Results. The 3 pathological types of PCAs, namely, persistent fetal vasculature (PFV), posterior capsule defect (PCD), and posterior lenticonus (PLC), presented in 129 (35.1%) CC eyes, while 238 (64.9%) eyes were recorded as CC without PCA. The percentages of PFV, PCD, and PLC were 10.9%, 26.7%, and 5.4% in CC eyes (n = 367), respectively. The most common concomitant of PFV eyes was PCD (42.5%), and PFV was the most frequent (17.3%) one in PCD eyes. PLC was only associated with PFV (15%) and PCD (50%). The occurrence rates of surgical complications ranged from 0 to 5.4%, and no statistical difference was found between the eyes with and without PCA (all P>0.05). Conclusions. PFV, PCD, and PLC play a very important role in the CCs. The effect of fetal vessels in PFV eyes might be an abnormally strong attachment on the posterior capsule, leading to PLC and PCD. Even in PCA patients, severe surgical complication can also be avoided with well-designed and skilled operation. This trial is registered with NCT03905044 at http://ClinicalTrials.gov.
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "PCD"

1

Ellis, Cameron B. "Tribopairs in Wellbore Drilling: A Study of PCD Tilting Pad Bearings in an Electric Submersible Pump." BYU ScholarsArchive, 2017. https://scholarsarchive.byu.edu/etd/7233.

Full text
Abstract:
A polycrystalline diamond was tested as a bearing material for a tilting pad thrust bearing to be used in an electric submersible pump, which elevates process fluids from the bottom of well bores. The goal of this study was to compare the PCD to a current best of technology, which is stainless steel with an engineering polymer.This study found that PCD can handle larger loads than current technology but is limited in size due to diamond sintering and manufacturing constraints. The maximum size is Ø75mm.
APA, Harvard, Vancouver, ISO, and other styles
2

Shah, Syed Mohammad Ali. "The optimisation of PCD bit performance in coal measure rocks." Thesis, University of Nottingham, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.385944.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Bian, Shuning. "Real-time monitoring of ultrasound and cavitation mediated drug delivery." Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:e5a774a9-5b93-4862-8dd9-0614d234ff28.

Full text
Abstract:
Drug delivery plays a crucial role in the chemotherapeutic treatment of cancerous solid tumours. A drug, no matter how potent, is only truly effective when it can be delivered to all targeted cells. In recent years it has been recognised that the poor response of tumours to chemotherapy is in part due to inadequate drug delivery. Numerous strategies have been developed to overcome this issue. Of particular interest to the present work is the application of ultrasound and cavitation, which has been shown to be capable of enhancing drug delivery in solid tumours. These enhancements are attributed to the acoustic cavitation of microbubbles and the effects cavitation induces in the surrounding tissue. To better understand how ultrasound and cavitation can enhance drug delivery, an instrument was developed that is capable of monitoring in real-time and in-situ the effect of ultrasound and cavitation on drugs and drug analogues within flow channel models. The developed instrument was used to investigate the effect of ultrasound and cavitation on drug-eluting beads used for chemoembolisation, the effects of drug loading on microbubble dynamics, the effects produced by different cavitation agents, and the performance of passive acoustic mapping as a means of cavitation monitoring. The findings of the above investigations include: more physiologically relevant characterisations of drug-eluting beads pharmacokinetics, the possibility of significant changes in microbubble dynamics due to drug loading, a lack of general correlation between detected cavitation activity and induced effects, and the potential of passive acoustic mapping for monitoring cavitation and ultrasound induced effects. These and other findings also demonstrate the utility of the developed instrument for studying the many facets and applications of ultrasound and cavitation mediated drug delivery.
APA, Harvard, Vancouver, ISO, and other styles
4

Trčka, Tomáš. "Analýza silového zatížení stopkových fréz s PCD s ohledem na jejich ostření." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2017. http://www.nusl.cz/ntk/nusl-318670.

Full text
Abstract:
Measurement of the force loading is a significant type of measurement in mechanical engineering applied to analyse important aspects in the machining process. In addition to the determination of specific material constants, it is possible to analyse, for example, various machining strategies, geometries of tools or the degree of wear of the cutting edges of cutting tools. This master’s thesis deals especially with the last two mentioned aspects which are subjects of an experiment on end mills with PCD inserts sharpened by a different technology. In the introductory part the cutting forces are theoretically analysed along with their measurement possibilities and the technology of the production of the mills including their sharpening – WEDM and EDM-G. One chapter is concerned with the milling of plastic materials, as PVC was the material used for the workpiece during the experiment. The first experimental part is devoted to the analysis of sharpened tools followed by the measurement of forces using the piezoelectric dynamometer and the subsequent analysis of the influence of the different tool geometry. The last conducted experiment monitors how the overall cutting forces of individual end mills sharpened by different technology changed over specific milling time slots.
APA, Harvard, Vancouver, ISO, and other styles
5

Marrone, Anna Filomena. "Retinoblastoma (Rb) regulation and programmed cell death (PCD) in dystrophic (mdx) skeletal muscle." Thesis, University of Cambridge, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.621356.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Ben, hamed Ibtissem. "Réponses cellulaires rapides de l’halophyte Cakile maritima au choc salin : analyse de leur implication dans la mort cellulaire programmée et l’adaptation." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS444.

Full text
Abstract:
Les travaux présentés dans cette thèse ont porté sur la specificité des réponses cellulaires de l’halophyte obligatoire Cakile maritima au choc salin et la régulation des événements précoces impliqués dans la mort cellulaire programmée et la survie en condition de salinité. Dans une première étape, nous avons montré que cette plante est aussi tolérante aux chocs salins répétés qu’au stress salin progressif. Cependant, on a observé de zones de mort cellulaires sur les feuilles âgées soumises à un choc salin sévère (400 mM NaCl). Pour mieux cerner la cascade d’événements impliqués dans ce processus de mort cellulaire, nous avons poursuivi nos expériences sur des suspensions cellulaires de C. maritima, dont nous avons-nous même optimisé les conditions d’obtention, et des suspensions cellulaires d’Arabidopsis thaliana (glycophyte modèle). Chez les deux espèces, nous avons observé une mort cellulaire programmée qui dépend de la durée et l’intensité du traitement salin appliqué, et qui met en jeu les mêmes événements cellulaires notamment la dépolarisation de la membrane plasmique due à l’entrée de Na+ par les NSCCs, un dysfonctionnement mitochondrial, une production d’anions superoxydes et une activation de protéines de type caspase. La tolérance de C. maritima au stress salin serait potentiellement due à une forte accumulation d’ascorbate qui permettrait à cette halophyte de mieux réduire les dommages générés par le stress oxydatif. C. maritima s’est aussi distinguée par une meilleure capacité de contrôler l’accumulation cytoplasmique de Na+, conduisant à la survie de ses cellules en condition de salinité. Cette étude sur la mort cellulaire induite par le NaCl chez les cellules en culture de C. maritima nous a aussi permis de mettre en évidence deux types de comportement dans cette population de cellules en culture : l’un lié à une dépolarisation soutenue en réponse au NaCl conduisant probablement à la mort de ces cellules, l’autre lié à une dépolarisation transitoire indiquant que l’influx de Na+ au travers des NSCC était régulé permettant probablement aux cellules présentant ce comportement de survivre en évitant l'accumulation excessive de Na+ dans le cytosol. Dans la dernière partie de ce travail, nous avons mis en évidence la capacité de C. maritima d’exclure Na+ via le système SOS. Ce résultat suggère l’existence d’une deuxième voie de signalisation induite parallèlement à celle conduisant à la mort cellulaire. Cette voie, impliquant une production rapide d’oxygène singulet, pourrait permettre un influx de Ca2+ dans le cytoplasme activant la protéine SOS3 et en cascade SOS2 et SOS1 et les H+-ATPases de la membrane plasmique permettant un efflux du Na+ via SOS1 hors des cellules
AbstractThis work aimed at understanding the specificity of cellular responses of the obligate halophyte Cakile maritima to salt shock and regulation of early events involved in programmed cell death and survival under salinity conditions. In a first step, we have shown that this plant is tolerant upon both repetitive salt shocks and gradual salt application. However, we have observed a cell death zones on older leaves subjected to a severe shock saline (400 mM NaCl). To better understand the cascade of events involved in the cell death process, we continued our experiments on suspension culture of C. maritima, which we have optimized ourselves the conditions for establishment and suspension culture of Arabidopsis thaliana (glycophyte model). In both species, salinity induced programmed cell death that depends on the duration and the intensity of the applied salt treatment. Also, the same cellular events, including depolarization of the plasma membrane due to the Na+ influx by NSCCs, mitochondrial dysfunction, production of superoxide anions and activation of caspase-like proteins, occurs early in response to salt stress. C. maritima tolerance to salt stress is potentially due to a strong accumulation of ascorbate that would allow this halophyte to better reduce damage generated by oxidative stress. C. maritima is also distinguished by a better ability to control the cytoplasmic accumulation of Na+, leading to the survival of its cells under salinity conditions. This study on cell death induced by NaCl in cell culture of C. maritima also allowed us to identify two types of behavior in this population of cells in culture: one related to a sustained depolarization in response to NaCl probably leading to death of these cells, the other linked to a transient depolarization indicating that the Na+ influx through the NSCC was probably regulated allowing cells exhibiting this behavior to survive by avoiding excessive accumulation of Na+ in the cytosol. In the last part of this work, we have demonstrated the ability of C. maritima to exclude Na+ via the SOS system. This result suggests the existence of a second signaling pathway induced in parallel to that leading to cell death. This pathway, involving a rapid production of singlet oxygen, could allow a Ca2+ influx in the cytoplasm that acts as an elicitor for activation of SOS3 protein and SOS2-SOS1 cascade and H+- ATPases of the plasma membrane allowing Na+ efflux via SOS1 out of cells
APA, Harvard, Vancouver, ISO, and other styles
7

Siddique, Abu Bakar. "Exploring the possibility of a people centred development (PCD) process in Rajoir Thana in Bangladesh." Thesis, University of Reading, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.314250.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Chittaranjan, Suganthi. "A functional genomics approach identifies novel genes involved in steroid-hormove induced programmed cell death in Drosophila." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/2725.

Full text
Abstract:
Programmed Cell death (PCD) is a highly conserved and genetically controlled event that plays important roles in animal development, homeostasis and disease. Our first objective was to discover and characterize new genes involved in PCD. Since many PCD genes are conserved in Drosophila, and steroid-induced PCD of larval salivary glands (SGs) is transcriptionally regulated with features of both apoptosis and autophagy, we used this exceptionally well-suited in vivo system and performed Serial Analysis of Gene Expression (SAGE) in three pre-death stages. SAGE identified 1244 expressed transcripts, including genes involved in autophagy, apoptosis, immunity, cytoskeleton remodeling, and proteolysis. Of the 1244 transcripts, 463 transcripts belonged to knownlpredicted genes and were 5-fold differentially expressed prior to cell death. Next, we investigated the role of differentially expressed genes from SAGE, in cell death or cell survival, by RNA interference (RNAi ) in l(2)mbn haemocyte Drosophila cells. l(2)mbn cells undergo morphological changes in response to ecdysone treatment, and ultimately undergo PCD. We used cell viability, cell morphology, and apoptosis assays to identify the death-related genes and determined their ecdysone dependency and function in cell death regulation. Our RNAi screen identified six new pro-death related genes, including SH3PXJ and Soxl4, and 21 new pro-survival genes including SoxN. Identification of Soxl4 as pro-death and SoxN as pro-survival suggests that these Sox box proteins may have opposing roles in ecdysone-mediated cell death. Our final objective was to elucidate the function of CG409], a Drosophila homologue of human TNF-alpha induced proteins 8 (TNFAIP8) we identified from SAGE. We created loss-of-function and overexpression mutants of CG4091 to study gene function in vivo and employed immunoprecipitation and mass-spectrometry assays to identify proteins interacting with CG409] in vitro. We identified two proteins that are involved in n-fatty acid oxidation and several cytoskeletal proteins as interaction partners. Immunofluorescence based assays in vivo and in vitro revealed that CG409] is necessary for cytoskeletal remodeling. Further, defects in CG4091 expression affect cellular functions such as autophagy and lipid metabolism/trafficking that require an intact cytoskeleton. Together, our studies provided new insights into the molecular mechanisms involved in Drosophila SG cell death.
APA, Harvard, Vancouver, ISO, and other styles
9

Moore, Daniel John. "Identification and characterisation of conserved ciliary genes expressed in Drosophila sensory neurons." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/17918.

Full text
Abstract:
Drosophila provide an excellent model organism in which to study cilia as there are only two ciliated cell types; the sensory neurons and sperm cells. The chordotonal neuron is one such ciliated cell and is required for hearing, proprioception and gravitaxis. Mechanical manipulation of the cilium that extends from the neuronal dendrite is required for signal transduction. Chordotonal neuronal differentiation is regulated by a transcription factor cascade. Atonal begins the cascade, which is then continued by RFX and Fd3F for ciliary genes (Cachero et al 2011, Newton et al 2012). Genes expressed in developing chordotonal neurons are downstream of these transcription factors and their characterisation can further elucidate how neuronal differentiation is regulated. Ciliary genes are highly enriched in developing chordotonal cells; uncharacterised genes enriched in these cells can therefore be considered candidate ciliary genes (Cachero et al 2011). A behavioural assay was conducted to identify further genes that could have a role in ciliary formation and function. Candidate genes were identified by combining enrichment data with previous genomic, proteomic and transcriptomic studies of cilia. A climbing assay of RNAi mediated knock down of these genes identified a number of candidates for future work. One gene found to be highly enriched in developing chordotonal neurons is CG11253. CG11253EY10866 P element insertion mutant flies show a mild uncoordinated phenotype in a climbing assay consistent with reduced chordotonal organ function. Male flies are also infertile due to a lack of motile sperm. CG11253 is expressed in motile ciliated cells and is conserved in organisms with motile cilia. CG11253 expression is also regulated by RFX and Fd3F, suggesting that it is involved in cilium motility. This was confirmed by electron microscopy, which showed disruption of axonemal dynein arm localisation in chordotonal cilia and sperm flagella. A CG11253::mVenus fusion protein was found to localise mainly to the cytoplasm and to a lesser extent the cilia of chordotonal neurons. Patients with symptoms consistent with Primary Ciliary Dyskinesia (PCD), a condition caused by cilium immotility, have subsequently been found to have point mutations in ZMYND10, the human homologue of CG11253. The identification of PCD patients with ZMYND10 mutations showed that investigating cilium motility in Drosophila chordotonal neurons could identify novel PCD genes. It was thought that investigating previously uncharacterised targets of Fd3F could identify novel genes involved in cilium motility and thus candidate PCD genes. CG31320 is a gene regulated by RFX and Fd3F and conserved in organisms with motile cilia. RNAi mediated knock down of CG31320 resulted in both a mild uncoordinated phenotype and male infertility due to a lack of motile sperm. Electron microscopy showed a complete loss of axonemal dynein arms in chordotonal neuron cilia. An mVenus fusion protein of CG6971, an inner dynein arm component, was also mislocalised from the cilia in CG3132027 deletion mutant larvae. This shows that CG31320 is required for the appropriate localisation of the axonemal dynein arms and thus cilium motility. This further showed that uncharacterised genes enriched in chordotonal neurons and regulated by Fd3F could be novel ciliary genes required for cilium motility. Our collaborators and Horani et al (2012) showed that the human homologue of CG31320 (HEATR2) is mutated in patients with PCD, further confirming that this method can be used to identify PCD genes. I have identified two factors required for cilium motility. Disruption of the axonemal dynein arms in both cases results in reduced coordination, and lack of fertility due to sperm immotility. Mutations in the human homologues of these genes have been found to result in PCD. This indicates that further PCD genes could be identified from genes enriched in Drosophila chordotonal neurons that are regulated by Fd3F.
APA, Harvard, Vancouver, ISO, and other styles
10

Young, Bennett. "Is the Arabidopsis peptide 'kiss of death' an inducer of programmed cell death?" Thesis, University of Manchester, 2010. https://www.research.manchester.ac.uk/portal/en/theses/is-the-arabidopsis-peptide-kiss-of-death-an-inducer-of-programmed-cell-death(33ac50ec-bd4f-4069-8618-bcd21e520b23).html.

Full text
Abstract:
Programmed Cell Death (PCD) is an essential process utilised for the defence and development of all multicellular organisms. In plants however, relatively little is known about the genes involved with the regulation and execution of this process. In particular, even less is known about the molecular components which act high up in the PCD pathway. In this thesis, we carried out an investigation into the novel peptide-encoding gene KISS OF DEATH (KOD). In Arabidopsis, KOD was found to be involved with mediating the elimination of the suspensor, an organ which undergoes developmental PCD. Two mutant alleles of KOD showed reduced PCD in both the suspensor and during heat-shock induced PCD of root hairs. Over-expression of KOD in plant tissues was sufficient to cause death in leaves or whole seedlings and involved the activation of caspase-like proteolytic activity. KOD-induced PCD was found to require light in leaves and is also sensitive to the PCD suppressor genes AtBI-1 and P35. We suggest that KOD acts high up in the PCD cascade as its expression resulted in depolarisation of the mitochondrial membrane, which is an early step in plant PCD. KOD appears to be a plant-specific peptide that is sufficient to induce PCD in Arabidopsis in the absence of external triggers. Typical BLAST searches yielded no obvious homolog for KOD, therefore a bioinformatics screen of the Arabidopsis genome was carried out. This screen for small genes similar in size to KOD enabled us to detect 10 previously unidentified genes, one of which may represent a putative KOD homolog. In summary, KOD appears to be a novel pro-PCD component of the Arabidopsis cell death machinery and represents the first plant peptide to be involved with a form of developmental PCD.
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "PCD"

1

Liadis, Nicole. The role of caspase-3 in regulating neurotrophic and NMDA-dependent PCD in the mammalian CNS in vivo. Ottawa: National Library of Canada, 2001.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
2

United States. Environmental Protection Agency and I. T. Corporation, eds. Photolysis/biodegradation of PCB and PCDD/PCDF contaminated soils. Cincinnati, OH: U.S. Environmental Protection Agency, 1994.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
3

Identification des domaines de soutien de la CEDEAO dans le cadre du programme communautaire de développement (PCD) : cas du Mali: Rapport final. [Mali]: République du Mali, Ministère de l'économie et des finances, 2009.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
4

Economic Community of West African States, Mali. Ministère des Maliens de l'extérieur et de l'intégration africaine, and Mali. Comité national de politique économique, eds. Identification des domaines de soutien de la CEDEAO dans le cadre du programme communautaire de développement (PCD) : cas du Mali: Rapport final. Bamako, Mali]: Ministere de l'Economie et des Finances, 2009.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
5

Repubbliche rosse: I simboli nazionali del Pci e del Pcf (1944-1953). Bologna: CLUEB, 2009.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
6

Armbrust, Steven. Programmer's reference manual for IBM personal computers. Homewood, Ill: Dow Jones-Irwin, 1986.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
7

Burton, Krakow, Neuhauser Edward F, Altwicker Elmar R, New York State Energy Research and Development Authority., Niagara Mohawk Power Corporation, and Rensselaer Polytechnic Institute, eds. Fundamental aspects of dioxin (PCDD) and furan (PCDF) formation from combustion: Final report. Albany, N.Y: NYSERDA, 1992.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
8

Steer, P. Ambient air sampling for PCDD/PCDF near two pulp mills in northern Ontario. [Toronto]: Ontario Environment, 1992.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
9

Elena, Aga Rossi, Quagliariello Gaetano, Libera università internazionale degli studi sociali (Rome, Italy), and Università degli studi dell'Aquila, eds. L' altra faccia della luna: I rapporti tra PCI, PCF e Unione Sovietica. Bologna: Il Mulino, 1997.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
10

Steve, Prokup, ed. Cellular and PCS/PCN telephones and systems: An overview of technologies, economics, and services. Fuquay-Varina, NC: APDG Pub., 1996.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Book chapters on the topic "PCD"

1

Braun-Falco, Markus, Henry J. Mankin, Sharon L. Wenger, Markus Braun-Falco, Stephan DiSean Kendall, Gerard C. Blobe, Christoph K. Weber, et al. "PCD." In Encyclopedia of Molecular Mechanisms of Disease, 1592. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_6932.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Braun-Falco, Markus, Henry J. Mankin, Sharon L. Wenger, Markus Braun-Falco, Stephan DiSean Kendall, Gerard C. Blobe, Christoph K. Weber, et al. "PCD Deficiency." In Encyclopedia of Molecular Mechanisms of Disease, 1592. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_5117.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Tahiri, Ahmed. "The PCD Method." In Numerical Methods and Applications, 563–71. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-36487-0_64.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Gladish, Daniel K. "Vascular Aerenchyma and PCD." In Plant Programmed Cell Death, 97–121. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-21033-9_5.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

John Conway, T., and Paul F. McCabe. "Plant Programmed Cell Death (PCD): Using Cell Morphology as a Tool to Investigate Plant PCD." In Advances in Plant Ecophysiology Techniques, 273–81. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-93233-0_16.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Beltrame, M., M. Fioretti, E. Kuljanic, and F. Miani. "Titanium Alloy Turbine Blades Milling with PCD Cutter." In Advanced Manufacturing Systems and Technology, 121–28. Vienna: Springer Vienna, 1996. http://dx.doi.org/10.1007/978-3-7091-2678-3_12.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Kuppuswamy, Ramesh, and Kerry Anne Airey. "Intelligent PCD Tool Testing and Prediction of Performance." In Lecture Notes on Multidisciplinary Industrial Engineering, 161–87. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-8767-7_7.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Philbin, P., S. Gordon, and N. Pretorius. "Wear Characteristics of PCD when Machining Wood Based Composites." In Proceedings of the 34th International MATADOR Conference, 133–38. London: Springer London, 2004. http://dx.doi.org/10.1007/978-1-4471-0647-0_20.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Quenum, Gandome Mayeul L. D., Nana A. B. Klutse, Eric A. Alamou, Emmanuel A. Lawin, and Philip G. Oguntunde. "Precipitation Variability in West Africa in the Context of Global Warming and Adaptation Recommendations." In African Handbook of Climate Change Adaptation, 1533–54. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-45106-6_85.

Full text
Abstract:
AbstractIt is commonly accepted that the Earth’s climate is changing and will continue to change in the future. Rising temperatures are one of the direct indicators of global climate change. To investigate how the rising global temperature will affect the spatial pattern of rainfall in West Africa, the precipitation and potential evapotranspiration variables from ten Global Climate Models (GCMs) under the RCP8.5 scenario were driven by the Rossby Centre regional atmospheric model (RCA4) from the COordinated Regional Climate Downscaling EXperiment (CORDEX) and analyzed at four specific global warming levels (GWLs) (i.e., 1.5 °C, 2.0 °C, 2.5 °C, and 3.0 °C) above the preindustrial level. This study utilized three indices, the precipitation concentration index (PCI), the precipitation concentration degree (PCD), and the precipitation concentration period (PCP) over West Africa to explore the spatiotemporal variations in the characteristics of precipitation concentrations. Besides, the analysis of the effect of the specified GWLs on the Consecutive Dry Days (CDD), Consecutive Wet Days (CWD), and frequency of the intense rainfall events allowed to a better understanding of the spatial and temporal patterns of extreme precipitation in West Africa. Results reveal that, for the projections simulations and at each GWL, the rainfall onset starts one month earlier in the Gulf of Guinea in response to the control period. To encourage adaptation to the various changes in climate in general, and particularly in respect of rainfall, this study proposes several adaptation methods that can be implemented at the local (country) level, as well as some mitigation and adaptation strategies at the regional (West African) level.
APA, Harvard, Vancouver, ISO, and other styles
10

Chen, Y., Liang Chi Zhang, and Joseph A. Arsecularatne. "Optical Surface Finish of PCD Composites by Dynamic Friction Polishing." In Optics Design and Precision Manufacturing Technologies, 226–31. Stafa: Trans Tech Publications Ltd., 2007. http://dx.doi.org/10.4028/0-87849-458-8.226.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "PCD"

1

Childers, Ronald D., and Gregory C. Miller. "PCD Technology Advances Sidetracking Capabilities." In IADC/SPE Drilling Conference. Society of Petroleum Engineers, 2000. http://dx.doi.org/10.2118/59185-ms.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Yamaguchi, Keishi, Takumi Sugimoto, Minoru Ota, and Kai Egashira. "Micro Grooving of Cemented Carbide Using PCD Blade." In JSME 2020 Conference on Leading Edge Manufacturing/Materials and Processing. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/lemp2020-8579.

Full text
Abstract:
Abstract Ultra–Agile Advanced Manufacturing System (U–AMS) has been proposed for an agile prototyping system of research and development, and Super Processing Center (SPC) has been developing as a core machine tool of U–AMS. SPC has high accuracy and rigidity by double column structure based on a vertical precision machining center, hydrostatic oil guides and hydro static/dynamic hybrid oil bearing. In addition, SPC can perform various processing functions by mounting various processing units. Micro grooving by grinding has been researching for one of the SPC unit. PCD blade was developed for micro grooving using SPC. PCD blade was made from PCD disc using wire electrical discharge machining. This paper describes the fabrication method of PCD blade, and the machining characteristics of cemented carbide using PCD blade. In the fabrication method of PCD blade, it was clarified that the cross-sectional shape of PCD blade depended on the feed speed of wire electrode. Micro grooving on cemented carbide surface was performed using developed PCD blade and SPC. As a result, it was confirmed that the micro grooves can be machined using PCD blade, and the width of groove was almost same value as the width of PCD blade. The wear of PCD blade after grooving with 200 grooves was estimated by the depth of grooves. As a result, it was clarified that the wear of PCD blade is approximately 5 μm.
APA, Harvard, Vancouver, ISO, and other styles
3

O'Connor, M. G., T. J. Hochstetler, N. Vanderbilt, and L. R. Young. "Primary Ciliary Dyskinesia (PCD) Diagnostic Testing Before and After Establishment as a PCD Clinical Center." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4381.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Kobbernagel, Helene, Frederik F. Buchvald, Laura Behan, Jane S. Lucas, Eric G. Haarman, Niels W. Rutjes, Anika Gross, et al. "Associations between PCD-specific health-related quality of life (QOL-PCD) outcomes and clinical measures." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa5050.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Shoemark, Amelia, Eva Polverino, Francesco Blasi, Felix C. Ringshausen, Anthony De Soyza, Montserrat Vendrell, Pieter C. Goeminne, et al. "Characteristics and outcomes of adults with primary ciliary dyskinesia (PCD): an EMBARC/BEAT-PCD analysis." In ERS International Congress 2021 abstracts. European Respiratory Society, 2021. http://dx.doi.org/10.1183/13993003.congress-2021.pa2062.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Lingwall, B. A., C. H. Cooley, and T. N. Sexton. "Polycrystalline Diamond Thrust Bearing Testing and Qualification for Application in Marine Hydrokinetic Machines." In ASME/STLE 2012 International Joint Tribology Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/ijtc2012-61061.

Full text
Abstract:
Polycrystalline diamond (PCD) bearings are designed for use in extreme environments; this includes process-fluid-lubricated applications such as those in oil and gas drilling turbines and marine hydrokinetic (MHK) energy machines. Past uses of PCD bearings in oil and gas down-hole tool applications have proven them to be robust, long lived, and rugged [1]. To be effective in MHK machines, PCD bearings must demonstrate adequate bearing efficiency and life in a submerged marine environment not nearly as severe as an oil well bore or a gas well bore. This paper discusses the advantages PCD bearings could provide when used in underwater MHK energy machines. Laboratory test results are presented that can help predict the performance of PCD in these MHK applications. Results from three types of tests are presented including tests that measure bearing capacity, those that observe and qualify hydrodynamic properties during testing, and those that evaluate diamond wear rates through a test representing the life time of a bearing in a MHK energy application. Failure tests conducted to measure bearing capacity revealed the PCD bearing could well endure conditions found in MHK machines, and coefficient of friction (COF) tests demonstrated the PCD ability to move from a boundary lubrication regime, to mixed mode lubrication, and then become hydrodynamic. The PCD wear test was designed to simulate years in the life of a tidal stream power generator, an MHK energy machine, and showed the PCD life is more than adequate for the MHK application. Bearing capacity, COF, and wear observed during laboratory testing illustrate that PCD thrust bearings can provide a robust, long lasting, and low maintenance bearing in MHK applications.
APA, Harvard, Vancouver, ISO, and other styles
7

Davis, Michael H. "Kodak professional PCD film scanner 4045." In IS&T/SPIE's Symposium on Electronic Imaging: Science and Technology, edited by Helen Marz and Robert L. Nielsen. SPIE, 1993. http://dx.doi.org/10.1117/12.144784.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Koster, L., P. Blochl, and L. Fabry. "Element Specific Diagnosis Using μ-PCD." In 1994 International Conference on Solid State Devices and Materials. The Japan Society of Applied Physics, 1994. http://dx.doi.org/10.7567/ssdm.1994.ld-13.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Noone, Peter J., Christina A. Olson, Maimoona A. Zariwala, Brock R. Baker, Kimberlie A. Burns, Heymut Omran, Margaret W. Leigh, and Michael R. Knowles. "Characterization Of Ciliary Axonemal Defects In PCD Patients With Biallelic Mutations In 5 PCD-Causing Genes." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a2485.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Da Silva Ribeiro, Davi, Igor Richtic Silva, Thiago Lobo, Luciana Borges, and Eunice Nunes. "Uma Revisão Sistemática Sobre Técnicas de Audio Games Para Promover Acessibilidade de Pessoas com Deficiência Visual no Uso de Games." In Escola Regional de Informática de Mato Grosso. Sociedade Brasileira de Computação - SBC, 2019. http://dx.doi.org/10.5753/eri-mt.2019.8602.

Full text
Abstract:
Este artigo apresenta os resultados preliminares de uma Revisão Sistemática sobre técnicas de Audio Games utilizadas na acessibilidade de Pessoas com Deficiência (PcD) visual em Ambientes Virtuais, especificamente, Games, bem como apresentar os principais aspectos acerca das técnicas de áudio games identificadas, a fim de promover interação e imersão para PcD visual. Os resultados mostraram que é possível implementar Games acessíveis a PcD visual.
APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "PCD"

1

Sandoval Rincón, Diana Marcela. Accesibilidad a servicios de agua y saneamiento, energía y transporte para personas con discapacidad en América Latina y el Caribe. Inter-American Development Bank, September 2021. http://dx.doi.org/10.18235/0003613.

Full text
Abstract:
La falta de accesibilidad en servicios públicos depende de contextos culturales, económicos, sociales y geográficos, entre otros, así como del tipo de discapacidad que una persona pueda tener. Dependiendo de estas variables, se presentarán barreras más o menos profundas y/o complejas. El documento recoge investigaciones y estudios de caso sobre las barreras físicas, sociales y comunicacionales que enfrentan las Personas con Discapacidad (PcD) para el acceso a servicios públicos en el sector de la Infraestructura y la Energía, específicamente en las áreas de Agua y Saneamiento, Energía y Transporte. En este trabajo se describen los tipos de barreras (arquitectónica, urbanística, a la comunicación y electrónica), asociadas a la prestación de los servicios públicos de agua y saneamiento, energía y transporte. Se identifican barreras de acceso y buenas prácticas (ejemplos cercanos e internacionales, de Estado, empresas públicas y privadas) de accesibilidad a los servicios públicos de PcD, para así generar lineamientos que minimicen y en lo posible eliminen las barreras de accesibilidad. Finalmente, en las conclusiones se presentan las oportunidades de mejora que se pueden implementar para eliminar-o reducir- las barreras de acceso a los servicios públicos.
APA, Harvard, Vancouver, ISO, and other styles
2

Cooley, Craig, H., Michael,, M. Khonsari, and Brent Lingwall. The Development of Open Water-lubricated Polycrystalline Diamond (PCD) Thrust Bearings for Use in Marine Hydrokinetic (MHK) Energy Machines. Office of Scientific and Technical Information (OSTI), November 2012. http://dx.doi.org/10.2172/1056274.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Farrel, A. PCC-PCE Communication and PCE Discovery Requirements for Inter-Layer Traffic Engineering. Edited by T. Takeda. RFC Editor, December 2011. http://dx.doi.org/10.17487/rfc6457.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Gafni, Yedidya, Moshe Lapidot, and Vitaly Citovsky. Dual role of the TYLCV protein V2 in suppressing the host plant defense. United States Department of Agriculture, January 2013. http://dx.doi.org/10.32747/2013.7597935.bard.

Full text
Abstract:
TYLCV-Is is a major tomato pathogen, causing extensive crop losses in Israel and the U.S. We have identified a TYLCV-Is protein, V2, which acts as a suppressor of RNA silencing. Intriguingly, the counter-defense function of V2 may not be limited to silencing suppression. Our recent data suggest that V2 interacts with the tomato CYP1 protease. CYP1 belongs to the family of papain-like cysteine proteases which participate in programmed cell death (PCD) involved in plant defense against pathogens. Based on these data we proposed a model for dual action of V2 in suppressing the host antiviral defense: V2 targets SGS3 for degradation and V2 inhibits CYP1 activity. To study this we proposed to tackle three specific objectives. I. Characterize the role of V2 in SGS3 proteasomal degradation ubiquitination, II. Study the effects of V2 on CYP1 maturation, enzymatic activity, and accumulation and, III. Analyze the effects of the CYP1-V2 interaction on TYLCV-Is infection. Here we describe results from our study that support our hypothesis: the involvement of the host's innate immune system—in this case, PCD—in plant defense against TYLCV-Is. Also, we use TYLCV-Is to discover the molecular pathway(s) by which this plant virus counters this defense. Towards the end of our study we discovered an interesting involvement of the C2 protein encoded by TYLCV-Is in inducing Hypersensitive Response in N. benthamianaplants which is not the case when the whole viral genome is introduced. This might lead to a better understanding of the multiple processes involved in the way TYLCV is overcoming the defense mechanisms of the host plant cell. In a parallel research supporting the main goal described, we also investigated Agrobacteriumtumefaciens-encoded F-box protein VirF. It has been proposed that VirF targets a host protein for the UPS-mediated degradation, very much the way TYLCV V2 does. In our study, we identified one such interactor, an Arabidopsistrihelix-domain transcription factor VFP3, and further show that its very close homolog VFP5 also interacted with VirF. Interestingly, interactions of VirF with either VFP3 or VFP5 did not activate the host UPS, suggesting that VirF might play other UPS-independent roles in bacterial infection. Another target for VirF is VFP4, a transcription factor that both VirF and its plant functional homolog VBF target to degradation by UPS. Using RNA-seqtranscriptome analysis we showed that VFP4 regulates numerous plant genes involved in disease response, including responses to viral and bacterial infections. Detailed analyses of some of these genes indicated their involvement in plant protection against Agrobacterium infection. Thus, Agrobacterium may facilitate its infection by utilizing the host cell UPS to destabilize transcriptional regulators of the host disease response machinery that limits the infection.
APA, Harvard, Vancouver, ISO, and other styles
5

Granot, David, and Richard Amasino. Regulation of Senescence by Sugar Metabolism. United States Department of Agriculture, January 2003. http://dx.doi.org/10.32747/2003.7585189.bard.

Full text
Abstract:
Research objectives a. Analyze transgenic plants that undergo rapid senescence due to increased expression of hexokinase. b. Determine if hexokinase-induced senescence accelerates natural senescence using senescence specific promoters that drive expression of a reporter gene (GUS) and a cytokinin producing gene (IPT - isopentyl transferase). c. Isolate and analyze plant genes that suppress sugar-induced cell death (SICD) in yeast, genes that potentially are involved in programmed cell death and senescence in plants. Background to the topic Leaf senescence is a regulated process of programmed cell death (PCD) in which metabolites are recycled to other active parts of the plant. Senescence associated genes (SAGs) are expressed throughout leaf senescence. Sugar flux and metabolism is thought to playa fundamental regulatory role in senescence. We found that transgenic tomato plants with high hexokinase activity, the initial enzymatic step of sugar (hexose) metabolism, undergo rapid leaf senescence, directly correlated with hexokinase activity. These plants provide a unique opportunity to analyze the regulatory role of sugar metabolism in senescence, and its relation to cytokinin, a senescence-inhibiting hormone. In addition, we found that sugar induces programmed cells death of yeast cells in direct correlation to hexokinase activity. We proposed to use the sugar induced cell death (SICD) to isolate Arabidopsis genes that suppress SICD. Such genes could potentially be involved in senescence induced PCD in plants. Major conclusions The promoters of Arabidopsis senescence-associated genes, SAG12 and SAGI3, are expressed in senescing tomato leaves similar to their expression in Arabidopsis leaves, indicating that these promoters are good senescence markers for tomato plants. Increased hexokinase activity accelerated senescence and induced expression of pSAG12 and pSAG13 promoters in tomato plants, suggesting that sugar regulate natural senescence via hexokinase. Expression of IPT, a cytokinin producing gene, under pSAG12 and pSAG13 promoters, delayed senescence of tomato leaves. Yet, senescence accelerated by hexokinase was epistatic over cytokinin, indicating that sugar regulation of senescence is dominant over the senescence-inhibiting hormone. A gene designated SFP1, which is similar to the major super family monosaccharide transporters, is induced during leaf senescence in Arabidopsis and may be involved in sugar transport during senescence. Accordingly, adult leaves accumulate sugars that may accelerate hexokinase activity. Light status of the entire plant affects the senescence of individual leaves. When individual leaves are darkened, senescence is induced in the covered leaves. However, whole adult plant placed in darkness show delayed senescence. In a search for Arabidopsis genes that suppress SICD we isolated 8 cDNA clones which confer partial resistance to SICD. One of the clones encodes a vesicle associated membrane protein - VAMP. This is the first evidence that vesicle trafficking might be involved in cell death. Implications Increased hexokinase activity accelerates senescence. We hypothesized that, reduced hexokinase activity may delay senescence. Preliminary experiments using a hexokinase inhibitor support this possible implication. Currently we are analyzing various practical approaches to delay leaf senescence via hexokinase inhibition. .
APA, Harvard, Vancouver, ISO, and other styles
6

Simms, D. A., and C. P. Butterfield. PC-based PCM (Pulse Code Modulation) telemetry data reduction system hardware. Office of Scientific and Technical Information (OSTI), February 1990. http://dx.doi.org/10.2172/7024568.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Yasukawa, S., and A. Farrel. Path Computation Clients (PCC) - Path Computation Element (PCE) Requirements for Point-to-Multipoint MPLS-TE. RFC Editor, June 2010. http://dx.doi.org/10.17487/rfc5862.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Lopez, D., Q. Wu, D. Dhody, Q. Ma, and D. King. IGP Extension for Path Computation Element Communication Protocol (PCEP) Security Capability Support in PCE Discovery (PCED). RFC Editor, January 2023. http://dx.doi.org/10.17487/rfc9353.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Granot, David, Richard Amasino, and Avner Silber. Mutual effects of hexose phosphorylation enzymes and phosphorous on plant development. United States Department of Agriculture, January 2006. http://dx.doi.org/10.32747/2006.7587223.bard.

Full text
Abstract:
Research objectives 1) Analyze the combined effects of hexose phosphorylation and P level in tomato and Arabidopsis plants 2) Analyze the combined effects of hexose phosphorylation and P level in pho1 and pho2 Arabidopsis mutants 3) Clone and analyze the PHO2 gene 4) Select Arabidopsis mutants resistant to high and low P 5) Analyze the Arabidopsis mutants and clone the corresponding genes 6) Survey wild tomato species for growth characteristics at various P levels Background to the topic Hexose phosphorylating enzymes, the first enzymes of sugar metabolism, regulate key processes in plants such as photosynthesis, growth, senescence and vascular transport. We have previously discovered that hexose phosphorylating enzymes might regulate these processes as a function of phosphorous (P) concentration, and might accelerate acquisition of P, one of the most limiting nutrients in the soil. These discoveries have opened new avenues to gain fundamental knowledge about the relationship between P, sugar phosphorylation and plant development. Since both hexose phosphorylating enzymes and P levels affect plant development, their interaction is of major importance for agriculture. Due to the acceleration of senescence caused by the combined effects of hexose phosphorylation and P concentration, traits affecting P uptake may have been lost in the course of cultivation in which fertilization with relatively high P (30 mg/L) are commonly used. We therefore intended to survey wild tomato species for high P-acquisition at low P soil levels. Genetic resources with high P-acquisition will serve not only to generate a segregating population to map the trait and clone the gene, but will also provide a means to follow the trait in classical breeding programs. This approach could potentially be applicable for other crops as well. Major conclusions, solutions, achievements Our results confirm the mutual effect of hexose phosphorylating enzymes and P level on plant development. Two major aspects of this mutual effect arose. One is related to P toxicity in which HXK seems to play a major role, and the second is related to the effect of HXK on P concentration in the plant. Using tomato plants we demonstrated that high HXK activity increased leaf P concentration, and induced P toxicity when leaf P concentration increases above a certain high level. These results further support our prediction that the desired trait of high-P acquisition might have been lost in the course of cultivation and might exist in wild species. Indeed, in a survey of wild species we identified tomato species that acquired P and performed better at low P (in the irrigation water) compared to the cultivated Lycopersicon esculentum species. The connection between hexose phosphorylation and P toxicity has also been shown with the P sensitive species VerticordiaplumosaL . in which P toxicity is manifested by accelerated senescence (Silber et al., 2003). In a previous work we uncovered the phenomenon of sugar induced cell death (SICD) in yeast cells. Subsequently we showed that SICD is dependent on the rate of hexose phosphorylation as determined by Arabidopsis thaliana hexokinase. In this study we have shown that hexokinase dependent SICD has many characteristics of programmed cell death (PCD) (Granot et al., 2003). High hexokinase activity accelerates senescence (a PCD process) of tomato plants, which is further enhanced by high P. Hence, hexokinase mediated PCD might be a general phenomena. Botrytis cinerea is a non-specific, necrotrophic pathogen that attacks many plant species, including tomato. Senescing leaves are particularly susceptible to B. cinerea infection and delaying leaf senescence might reduce this susceptibility. It has been suggested that B. cinerea’s mode of action may be based on induction of precocious senescence. Using tomato plants developed in the course of the preceding BARD grant (IS 2894-97) and characterized throughout this research (Swartzberg et al., 2006), we have shown that B. cinerea indeed induces senescence and is inhibited by autoregulated production of cytokinin (Swartzberg et al., submitted). To further determine how hexokinase mediates sugar effects we have analyzed tomato plants that express Arabidopsis HXK1 (AtHXK1) grown at different P levels in the irrigation water. We found that Arabidopsis hexokinase mediates sugar signalling in tomato plants independently of hexose phosphate (Kandel-Kfir et al., submitted). To study which hexokinase is involved in sugar sensing we searched and identified two additional HXK genes in tomato plants (Kandel-Kfir et al., 2006). Tomato plants have two different hexose phosphorylating enzymes; hexokinases (HXKs) that can phosphorylate either glucose or fructose, and fructokinases (FRKs) that specifically phosphorylate fructose. To complete the search for genes encoding hexose phosphorylating enzymes we identified a forth fructokinase gene (FRK) (German et al., 2004). The intracellular localization of the four tomato HXK and four FRK enzymes has been determined using GFP fusion analysis in tobacco protoplasts (Kandel-Kfir et al., 2006; Hilla-Weissler et al., 2006). One of the HXK isozymes and one of the FRK isozymes are located within plastids. The other three HXK isozymes are associated with the mitochondria while the other three FRK isozymes are dispersed in the cytosol. We concluded that HXK and FRK are spatially separated in plant cytoplasm and accordingly might play different metabolic and perhaps signalling roles. We have started to analyze the role of the various HXK and FRK genes in plant development. So far we found that LeFRK2 is required for xylem development (German et al., 2003). Irrigation with different P levels had no effect on the phenotype of LeFRK2 antisense plants. In the course of this research we developed a rapid method for the analysis of zygosity in transgenic plants (German et al., 2003).
APA, Harvard, Vancouver, ISO, and other styles
10

Dickman, Martin B., and Oded Yarden. Genetic and chemical intervention in ROS signaling pathways affecting development and pathogenicity of Sclerotinia sclerotiorum. United States Department of Agriculture, July 2015. http://dx.doi.org/10.32747/2015.7699866.bard.

Full text
Abstract:
Abstract: The long-term goals of our research are to understand the regulation of sclerotial development and pathogenicity in S. sclerotior11111. The focus in this project was on the elucidation of the signaling events and environmental cues involved in the regulation of these processes, utilizing and continuously developing tools our research groups have established and/or adapted for analysis of S. sclerotiorum, Our stated objectives: To take advantage of the recent conceptual (ROS/PPs signaling) and technical (amenability of S. sclerotiorumto manipulations coupled with chemical genomics and next generation sequencing) developments to address and extend our fundamental and potentially applicable knowledge of the following questions concerning the involvement of REDOX signaling and protein dephosphorylation in the regulation of hyphal/sclerotial development and pathogenicity of S. sclerotiorum: (i) How do defects in genes involved in ROS signaling affect S. sclerotiorumdevelopment and pathogenicity? (ii) In what manner do phosphotyrosinephosphatases affect S. sclerotiorumdevelopment and pathogenicity and how are they linked with ROS and other signaling pathways? And (iii) What is the nature of activity of newly identified compounds that affect S. sclerotiori,111 growth? What are the fungal targets and do they interfere with ROS signaling? We have met a significant portion of the specific goals set in our research project. Much of our work has been published. Briefly. we can summarize that: (a) Silencing of SsNox1(NADPHoxidase) expression indicated a central role for this enzyme in both virulence and pathogenic development, while inactivation of the SsNox2 gene resulted in limited sclerotial development, but the organism remained fully pathogenic. (b) A catalase gene (Scatl), whose expression was highly induced during host infection is involved in hyphal growth, branching, sclerotia formation and infection. (c) Protein tyrosine phosphatase l (ptpl) is required for sclerotial development and is involved in fungal infection. (d) Deletion of a superoxidedismutase gene (Sssodl) significantly reduced in virulence on both tomato and tobacco plants yet pathogenicity was mostly restored following supplementation with oxalate. (e) We have participated in comparative genome sequence analysis of S. sclerotiorumand B. cinerea. (f) S. sclerotiorumexhibits a potential switch between biotrophic and necrotrophic lifestyles (g) During plant­ microbe interactions cell death can occur in both resistant and susceptible events. Non­ pathogenic fungal mutants S. sclerotior111n also cause a cell death but with opposing results. We investigated PCD in more detail and showed that, although PCD occurs in both circumstances they exhibit distinctly different features. The mutants trigger a restricted cell death phenotype in the host that unexpectedly exhibits markers associated with the plant hypersensitive (resistant) response. Using electron and fluorescence microscopy, chemical effectors and reverse genetics, we have established that this restricted cell death is autophagic. Inhibition of autophagy rescued the non-pathogenic mutant phenotype. These findings indicate that autophagy is a defense response in this interaction Thus the control of cell death, dictated by the plant (autophagy) סr the fungus (apoptosis), is decisive to the outcome of certain plant­ microbe interactions. In addition to the time and efforts invested towards reaching the specific goals mentioned, both Pls have initiated utilizing (as stated as an objective in our proposal) state of the art RNA-seq tools in order to harness this technology for the study of S. sclerotiorum. The Pls have met twice (in Israel and in the US), in order to discuss .נחd coordinate the research efforts. This included a working visit at the US Pls laboratory for performing RNA-seq experiments and data analysis as well as working on a joint publication (now published). The work we have performed expands our understanding of the fundamental biology (developmental and pathogenic) of S. sclerotioז111וז. Furthermore, based on our results we have now reached the conclusion that this fungus is not a bona fide necrotroph, but can also display a biotrophic lifestyle at the early phases of infection. The data obtained can eventually serve .נ basis of rational intervention with the disease cycle of this pathogen.
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'PCD' for particular source types:
Journal articles Dissertations / Theses Books
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography