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Academic literature on the topic 'PCO2 AND HCO3) IN COPD PATIENTS'
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Journal articles on the topic "PCO2 AND HCO3) IN COPD PATIENTS"
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Novovic, Milos, and Vesna Topic. "Correlation between arterial and venous blood gas analysis parameters in patients with acute exacerbation of chronic obstructive pulmonary disease." Srpski arhiv za celokupno lekarstvo 140, no. 7-8 (2012): 436–40. http://dx.doi.org/10.2298/sarh1208436n.
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Introduction. Arterial blood gas (ABG) analyses have an important role in the assessment and monitoring of the metabolic and oxygen status of patients with acute exacerbation of chronic obstructive pulmonary disease (COPD). Arterial puncture could have a lot of adverse effects, while sampling of venous blood is simpler and is not so invasive. Objective. The aim of this study was to evaluate whether venous blood gas (VBG) values of pH, partial pressure of carbon dioxide (PCO2), partial oxygen pressure (PO2), bicarbonate (HCO3), and venous and arterial blood oxygen saturation (SO2) can reliably predict ABG levels in patients with acute exacerbation of COPD. Methods. Forty-seven patients with a prior diagnosis of COPD were included in this prospective study. The patients with acute exacerbation of this disease were examined at the General Hospital EMS Department in Prijepolje. ABG samples were taken immediately after venous sampling, and both were analyzed. Results. The Pearson correlation coefficients between arterial and venous parameters were 0.828, 0.877, 0.599, 0.896 and 0.312 for pH, PCO2, PO2, HCO3 and SO2, respectively. The statistically significant correlation between arterial and venous pH, PCO2 and HCO3, values was found in patients with acute exacerbation of COPD (p<0.001). Conclusion. When we cannot provide arterial blood for analysis, venous values of the pH, Pv,CO2 and HCO3 parameters can be an alternative to their arterial equivalents in the interpretation of the metabolic status in patients with acute exacerbation of COPD, while the values of venous Pv,O2 and Sv,O2 cannot be used as predictors in the assessment of oxygen status of such patients.
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Khadija, Aslam Bara Dr. Aiesha Baloch Aysha. "A CROSS-SECTIONAL STUDY TO ASSESS THE ASSOCIATION OF VENOUS AND ARTERIAL BLOOD GASES (PH, PCO2 AND HCO3) IN COPD PATIENTS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 10 (2018): 9852–56. https://doi.org/10.5281/zenodo.1461025.
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<strong><em>Objective: </em></strong><em>Body acid base balance can best be determined through the analysis of arterial blood gas. It is also an important assessment tool for acid base balance verification in the human body. COPD (Chronic Obstructive Pulmonary Disease) is a disease that limit the airflow that cannot be reversed and causes failure of the respiration process. Our aim of this particular research was to determine the association between venous and arterial blood gases in the COPD patients.</em> <strong><em>Material and Methods: </em></strong><em>The research is cross-sectional and it is completed in the Chest Medicine Department of Allied Hospital, Faisalabad (February 2017 to December 2017). A total of one hundred participants took part in the research. Every patient fulfilled the prescribed inclusion criteria. An informed consent was also secured before the commencement of research. Patients were drained for blood samples anaerobically from dorsal hand vein and radial artery with the help of two separate syringes. We analyzed the samples for pH, HCO3 and PCO2. Data analysis was made through SPSS software.</em> <strong><em>Results: </em></strong><em>The outcomes reflected a patient’s mean age of (52.68 ± 10.51) years. There was a strong association between ABGs and VBGs as analyzed through pH, HCO3 and PCO2 which is r = 0.913, 0.994 and 0.999 respectively. A significant P-value was under 0.0001.</em> <strong><em>Conclusion: </em></strong><em>There was a strong association of VBGs and </em><em>ABG’s in COPD patients.</em>
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Nusrullah, Muhammad, Muhammad Younus, and Yasir Nasir. "Relationship between Arterial and Venous Blood Gases in Patients Presenting with Chronic Obstructive Pulmonary Disease." Annals of King Edward Medical University 24, no. 1 (2018): 684–88. http://dx.doi.org/10.21649/akemu.v24i1.2343.
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Arterial blood gas analysis is an important test for determining acid base balance of the body. Chronic obstructive pulmonary disease is characterized by chronic airflow limitation which is not fully reversible and it can lead to respiratory failure. Objective: To determine the correlation between arterial and venous blood gases in patients presenting with chronic obstructive pulmonary disease. Material and Methods: This cross sectional study was conducted at Department of Chest Medicine, Mayo Hospital, Lahore, Pakistan. After meeting the inclusion criteria, 100 patients were enrolled. Informed consent was taken and demographic information was obtained. Blood sample was obtained anaerobically from the radial artery and from a dorsal hand vein using 2 separate 5cc BD heparinized syringes with needle size 22G for each patientand pH, PCO2, and HCO3 were analyzed. All the collected data was entered and analyzed on SPSS version 21.Results: The mean age of the patients was 52.68±10.51 years. Strong relationship was found between the VBGs and ABGs in pH, PCO2 and HCO3 i.e. r=0.913, 0.999 and 0.994 (p-value <0.0001), respectively. Conclusion: A strong correlation was found among ABG’s and VBGs in patients presenting with COPD.
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Sathindra Sasmita, B., Janmejoy Sengupta, and Indraneel Dasgupta. "COMPARATIVE EVALUATION OF CAPILLARY BLOOD GASES AS WITH ARTERIAL BLOOD GASES IN PATIENTS OF COPD WITH ACUTE EXACERBATION PRESENTING TO EMERGENCY DEPARTMENT: A PROSPECTIVE OBSERVATIONAL STUDY." International Journal of Advanced Research 8, no. 10 (2020): 553–91. http://dx.doi.org/10.21474/ijar01/11880.
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Aim: The aim of this study is to investigate the correlation between selected variables of capillary blood gas (CBG) and Arterial blood gas (ABG)values for assessing values of pH, bicarbonate (HCO3), partial pressure of oxygen (pO2), partial pressure of carbon dioxide (pCO2) in patients with acute exacerbation of COPD presenting to the Emergency department of Peerless hospital. Our study on reliability of CBG over ABG is aimed to make blood gas analysis easier, quicker, less painful and equally reliable. Settings And Design: This was a prospective observational study carried out in a tertiary care centre in Kolkata. Materials And Methods: This study was carried out in Peerless hospital and B.K.Roy Research Centre, Kolkata over a period of 1 year. Total of 90 patients who presented to Emergency department with acute exacerbation of COPD patients were included in the study. Informed consent was taken from all the patients recruited in this study. The blood samples were drawn simultaneously from the radial artery by an arterial puncture into a heparinized syringe and the fingertip by a finger prick into a capillary tube of every patient participating in the study. Initially, capillary sample was collected and immediately after that, an arterial sample was taken from the radial artery in order to assess the agreement between the capillary and arterial samples. These samples obtained were analysed immediately by the blood gas analyser (AVL Compact 3, Roche Diagnostics GmbH, Mannheim, Germany) of the Emergency Department for values of acid-base and oxygenation: pH, PO2, PCO2and HCO3 values. Blood gases were obtained only if the patient needed blood gases analysis for clinical decisions. Care was taken to avoid exposing the blood droplet to air, and the arterial sample was continuously turned to avoid clotting. In addition, the measurement of oxygen saturation (SpO2) was also obtained from the finger pulse oximeter in the emergency (Noninvasive pulse oximeter).
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Kancherla, Roopa, Senthil Dhanasekaran, Srinivas Rajagopal, and Dheeraj Kattula. "Predictors of post discharge home oxygen therapy and Bilevel positive airway pressure therapy in stable hypercapnoea." Pulmon 23, no. 2 (2021): 91–97. http://dx.doi.org/10.4103/0973-3809.364151.
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Background: Hospital admission for acute exacerbation of COPD (AE-COPD) accounts for 70% of total costs of COPD treatment, and treatment cost is related to the duration of hospital stay. If post-discharge supportive care is required an extra cost will be added. The objectives of this study are to determine the predictive factors of post-discharge supportive care (Domiciliary oxygen, Bi-level positive airway pressure) in known COPD patients who got admitted with acute exacerbation. This is likely to help the treating physician to prime the family and plan an early discharge of the patient with supportive care instead of waiting for the patient to be off oxygen or BiPAP support. Methods: This is a retrospective study done at the pulmonology department of tertiary care hospital from January 2018-Jan 2019. Data sources were electronic medical records and the hospital discharge minimum data set. This study included 89 known COPD subjects who were not on prior supportive care (Long term oxygen therapy or home BIPAP) and were admitted for the management of acute exacerbation. Clinical parameters like symptoms at onset and the duration of symptoms (cough, fever, breathlessness, sputum production),comorbidities, initial blood investigations(complete blood counts, serum creatinine, arterial blood gas analysis, sputum culture reports)radiological findings, treatment details, pulmonary function test were evaluated with appropriate statistical tests. Parameters associated with post-discharge supportive care were evaluated. Results: A total of 89 patients were included in the study. Four patients were excluded because of the death. Presence of type II respiratory failure related findings like respiratory acidosis PH (P=0.02), elevated bicarbonate HCO3 (P=0.01), elevated carbon dioxide level PCO2 (p=0.007) in the ABG, and the requirement of non-invasive ventilation (P=0.00), Chest X-ray finding of hyperinflation (P=0.03) and treatment-related variables like prolonged duration of hospitalization (P<0.01) were associated with post-discharge supportive care (Home oxygen therapy and BiPAP support) in univariate analysis. In the multivariate analysis hyperinflation (Odds ratio OR-4.73; 95% confidence interval; 1.37-16.33), noninvasive ventilation (OR-4.9; 95% CI: 1.29-18.47), and prolonged duration of hospitalization (OR-1.32; 95% CI: 1.05-1.66) remained significantly associated with post-discharge home oxygen therapy and home BiPAP therapy. Conclusion: This study results conclude that severe disease as marked by hyperinflation on Chest X-ray, presence of type II respiratory failure related changes in the ABG and requirement of non-invasive ventilation, and longer duration of hospitalization predicts the post-discharge supportive care. These findings can help the clinician to prepare for earlier discharge with post-discharge supportive care.
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Eljatin, Dwinka Syafira, Muhammad Ridho Akbar Eljatin, I. Made Dwi Mertha Adnyana, Muhammad Bayu Zohari Hutagalung, and Muhamad Frendy Setyawan. "Excessive Use of Nipah Leaf Membrane Cigarettes Increases the Severity of Spontaneous Pneumothorax: A Case study from Jambi, Indonesia." Journal of Pharmaceutical and Health Research 4, no. 1 (2023): 9–13. http://dx.doi.org/10.47065/jharma.v4i1.2820.
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Nipah (Nypa fruticans) is a type of palm that is widely used by the community. The local people of Jambi use Nipah leaves as a tobacco membrane for cigarettes. However, we found reports of cigarette use cases having implications for the severity of spontaneous pneumothorax disease. A 57-year-old man came to the emergency room suffering from shortness of breath, right-side chest discomfort, yellowish-green sputum cough, abdominal pain, nausea, weakness, decreased appetite, and inability to sleep. For two years, this man consumed ten Nipah membrane cigarettes he made independently daily, resulting in lung disease. The lungs were found to be asymmetrical with the weakened fremitus of the right lung stem; percussion revealed hyper resonance in the right lung and resonance in the left lung; auscultation revealed the presence of a decrease in vesicular breathing sounds in the right lung, and other breathing sounds crackling in both lungs. The patient's severe partially compensatory respiratory acidosis indicated levels of pH, pO2, pCO2, HCO3, total CO2, and BE. Sinus tachycardia, normoaxis and suitable atrial hypertrophy were found. The luscen region is visible, and the white line of the pleura on the right hemithorax shows the pneumothorax of the right lung. This case is relatively rare, and excess Nipah leaf membrane cigarettes increase the severity of spontaneous pneumothorax disease that causes COPD.
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Hoffman, William E., Fady T. Charbel, Guy Edelman, and James I. Ausman. "Brain tissue acid-base changes during ischemia." Neurosurgical Focus 2, no. 5 (1997): E5. http://dx.doi.org/10.3171/foc.1997.2.5.5.
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It is likely that brain tissue acidosis during ischemia is associated with neuronal injury. The authors measured brain extracellular H+, PCO2 and HCO3- concentrations during an ischemic event produced by temporary occlusion of the middle or anterior cerebral arterial distributions, with a 10-minute recovery period. Patients who were to undergo craniotomy for cerebrovascular surgery were recruited for the study. A probe that measures PCO2, pH, and temperature was inserted into tissue at risk for ischemia during temporary arterial occlusion. As a control for this treatment, PaCO2 was increased 10 mm Hg in five patients over a 10-minute period. Under baseline conditions, there was no difference in arterial blood pressure, blood gas levels, or brain temperature between patients who underwent temporary arterial occlusion or those in whom hypercapnia was induced. In patients in whom hypercapnia was induced, H+, PCO2, and HCO3- concentrations increased and all values returned to baseline levels within 10 minutes. In 10 patients who underwent a median 9-minute arterial occlusion, transient ischemia was seen with an increase in tissue H+ and PCO2 levels of 100% and 60%, respectively, and a 20% decrease in HCO3-levels. After a 10-minute postischemic recovery, only PCO2 had returned to baseline levels. These results are consistent with a rapid equilibration of lactic acidosis across the cell membrane during ischemia which decreases HCO3- concentration. After ischemia, extracellular acidosis may be prolonged because of the extrusion of H+ from the cell by membrane ion exchange.
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Shisodiya, Kunalsinh Khushalsinh, and Milind Vyawahare. "Study of Correlation of Arterial Blood Gas Measurements with Peripheral Venous Blood Gas Values in Adult Patients Admitted in ICU in Tertiary Care Hospital in Central India – A Cross-Sectional Study." Vidarbha Journal of Internal Medicine 33 (April 6, 2023): 21–26. http://dx.doi.org/10.25259/vjim_34_2022.
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Objectives: Arterial blood gas (ABG) analysis is an essential investigation for assessment of ventilation, oxygenation and acid–base status in critically ill patients. Arterial puncture to obtain arterial blood is more invasive procedure than venous and has more potential complications. The present study was undertaken to find out the correlation between arterial and peripheral venous blood gas (VBG) values for PO2 (Partial pressure of oxygen), PCO2 (Partial pressure of carbon dioxide), pH (Potential of hydrogen) and HCO3 (bicarbonates). Material and Methods: A total of 131 consecutive patients admitted to intensive care unit (ICU) requiring ABG analysis to determine their acid–base status or ventilatory status were included in the study. Arterial and venous blood samples were obtained with a heparinised syringe within <15 min, after performing modified Allen’s test and were analysed using blood gas analysis machine. The mean of pH, pCO2, HCO3, and PO2, values in arterial and venous samples was determined, along with peripheral arterial oxygen saturation (SpO2) of patients. Results: ABG and VBG analysis correlated well for pH, pCO2 and HCO3, as their correlation coefficient (r) were 0.976, 0.992 and 0.984, respectively, whereas PO2 has correlation coefficient of 0.010 which suggests that there was poor correlation in PO2. For each unit increase in pCO2, pH and HCO3 of VBG, all these ABG changes by 0.9831 units, 0.914 units and 0.992 units, respectively. Peripheral O2 saturation (SpO2) correlates well with arterial O2 saturation, however, does not correlate with venous O2 saturation. Conclusion: The results show that VBG analysis can be a substitute for ABG for evaluation of ventilatory function and acid–base imbalance for pH, pCO2 and HCO3 in patients of ICU setup in many clinical contexts.
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Prashant, Kumar Gupta, Shankar Kumar Uma, and Kumar Sinha Parmod. "A Comparative Evaluation of Venous Blood Gas between Arterial and Venous Blood Samples in Patients of Acute Breathlessness." International Journal of Current Pharmaceutical Review and Research 15, no. 11 (2023): 743–47. https://doi.org/10.5281/zenodo.11613724.
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AbstractAim: The aim of the present study was to compare venous blood gas assessments for variables such as pH, pCO2,bicarbonate and base excess between arterial and venous blood samples.Methods: This Prospective study was conducted at ANMMCH Gaya by Department of Emergency Medicine forthe period of 2 years. 70 patients were included in the study.Results: It was observed that the mean respiratory rate of the study conducted came out to be 32.2 breaths perminute. The mean SpO2 of the patients observed to be 88.4 at room air. The mean pH in arterial blood came outto be 7.43. The mean pH of venous sample observed to be 7.35 with p value of .028. The mean pCO2 values ofarterial blood observed to be 33.07. The mean pCO2 value of the venous blood samples was observed to be 39.51.The mean arterial HCO3 level in the sample came out to be 17.63. The mean venous HCO3 value in the samplecame out to be 20.07. The mean PO2 level of arterial blood came out to be 92.76. The mean PO2 level of venousblood came out to be 65.46.Conclusion: The blood gas values for pH and HCO3 showed excellent agreement and correlation and can beconsidered clinically interchangeable with arterial values. On venous pCO2 we found differing results andtherefore suggest the possible implementation of arterialization of venous blood gas which will make all thesevalues even more accurate and will allow the use of venous pCO2 in the clinical setting.
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Pujar, Ganesh, Umesh G. Rajoor, and Anand Chavan. "Correlation of Arterial and Central Venous Blood Gas Measurements in Critically Ill Patients at Intensive Care Unit of a Tertiary Care Center." APIK Journal of Internal Medicine 13, no. 2 (2024): 123–27. https://doi.org/10.4103/ajim.ajim_48_24.
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Background and Objective: Arterial blood gas (ABG) analysis is an important step in assessing the adequacy of oxygenation and ventilation and for monitoring acid–base disturbances. Arterial puncture is associated with complications, so central venous blood gas analysis (CVBG) is used as an alternative to ABG analysis. The objective of this study is to assess the relationship between pH, bicarbonate (HCO3), partial pressure of oxygen, base excess, and partial pressure of carbon dioxide (PCO2) values obtained from arterial and central venous blood samples in critically ill patients admitted to an intensive care unit (ICU). Materials and Methods: This single-center, prospective study aimed to assess the correlation between ABG and CVBG measurements among patients admitted to the medicine ICU. Two paired blood samples of both arterial and venous blood, 12 h apart, were collected from 30 patients. The correlation between ABG and CVBG was computed using Epi Info software. Results: The mean ± standard deviation (SD) of arterial pH and PCO2 was 7.36 ± 0.09 and 35.47 ± 9.74, respectively. The mean ± SD of venous pH and PCO2 was 7.36 ± 0.10 and 35.69 ± 9.99, respectively. The correlation between arterial and venous pH was r = 0.79 (P < 0.001), and PCO2 was r = 0.90 (P < 0.001). The mean ± SD of arterial HCO3 and base excess was 17.75 ± 8.56 and − 1.67 ± 8.82, respectively. The mean ± SD of venous HCO3 and base excess was 18.98 ± 5.80 and − 1.98 ± 9.46, respectively. The correlation between arterial and venous HCO3 was r = 0.87 (P < 0.001), and base excess was r = 0.81 (P < 0.001), suggesting a statistically significant correlation in the aforementioned parameters. Conclusion: Our study demonstrates a strong correlation between ABG and CVBG for pH, PCO2, HCO3, and base excess. These findings suggest that CVBG analysis can be a reliable alternative to ABG analysis in critically ill ICU patients, especially in resource-limited settings. This approach can reduce patient discomfort and complications associated with arterial punctures, streamlining emergency care.
Conference papers on the topic "PCO2 AND HCO3) IN COPD PATIENTS"
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Dierckx, W., K. Ides, Y. De Meyer, E. Lauwers, E. Franck, and W. De Backer. "Transcutaneous PCO2 (TcPCO2) in COPD patients during incremental exercise test (IET)." In ERS International Congress 2022 abstracts. European Respiratory Society, 2022. http://dx.doi.org/10.1183/13993003.congress-2022.2524.
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Leprat, Thibault, Fabrice Ivanes, Marchand-Adam Sylvain, and Laurent Plantier. "Transcutaneous PCO2-based dead space ventilation is highly accurate to discriminate COPD patients from healthy controls at submaximal exercise." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.2560.
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