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1

Cho, Kyung-Hyun, Ashutosh Bahuguna, Ji-Eun Kim, and Sang Hyuk Lee. "Efficacy Assessment of Five Policosanol Brands and Damage to Vital Organs in Hyperlipidemic Zebrafish by Six-Week Supplementation: Highlighting the Toxicity of Red Yeast Rice and Safety of Cuban Policosanol (Raydel®)." Pharmaceuticals 17, no. 6 (2024): 714. http://dx.doi.org/10.3390/ph17060714.

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Policosanol is a mixture of long-chain aliphatic alcohols (LCAAs) derived from various plant and insect origins that are marketed by various companies with distinct formulations and brand names. Policosanols offer several beneficial effects to treat dyslipidemia and hypertension; however, a comprehensive functionality comparison of various policosanol brands has yet to be thoroughly explored. In the present study five distinct policosanol brands from different origins and countries, Raydel-policosanol, Australia (PCO1), Solgar-policosanol, USA (PCO2), NutrioneLife-monacosanol, South Korea (PCO
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Goyal, Nitin, Georgios Tsivgoulis, Chris Nickele, et al. "Posterior circulation CT angiography collaterals predict outcome of endovascular acute ischemic stroke therapy for basilar artery occlusion." Journal of NeuroInterventional Surgery 8, no. 8 (2015): 783–86. http://dx.doi.org/10.1136/neurintsurg-2015-011883.

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IntroductionThe natural history of acute ischemic stroke (AIS) due to basilar artery occlusion (BAO) is poor. Endovascular reperfusion therapy (EVT) improves recanalization rates in patients with emergent large vessel intracranial occlusion.ObjectiveTo examine the hypothesis that good collateral patterns identified by pretreatment CT angiography (CTA) might be associated with favorable outcomes after EVT.MethodsWe conducted a retrospective chart review of patients presenting with AIS due to BAO in a tertiary care stroke center during a 4-year period. BAO was diagnosed by CTA in all cases. Admi
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Rosato, Richard, Gabriela Comptdaer, Ryan Mulligan, et al. "Increased focal internal carotid artery angulation in patients with posterior communicating artery aneurysms." Journal of NeuroInterventional Surgery 12, no. 11 (2020): 1142–47. http://dx.doi.org/10.1136/neurintsurg-2020-015883.

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BackgroundAneurysms at the posterior communicating artery (PCOM) origin represent the most common location on the internal carotid artery (ICA), and are associated with greater recurrence following endovascular treatment. We evaluate the association between ICA angulation in three-dimensional (3D) space and PCOM aneurysmal development, using high-resolution 3D rotational angiography (3DRA) studies.Methods3DRA datasets were evaluated in 70 patients with PCOM aneurysms, 31 non-aneurysmal contralateral, and 86 healthy controls (187 total). The local angle formed by upstream and downstream ICA seg
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Merino, Paulina M., Claudio Villarroel, Cristián Jesam, Patricia López, and Ethel Codner. "New Diagnostic Criteria of Polycystic Ovarian Morphology for Adolescents: Impact on Prevalence and Hormonal Profile." Hormone Research in Paediatrics 88, no. 6 (2017): 401–7. http://dx.doi.org/10.1159/000481532.

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Background: The ultrasonographic criteria used to identify polycystic ovarian morphology (PCOM) during adolescence have changed over time. Recently, a Worldwide Pediatric Consensus (PedC) defined PCOM using stricter criteria than the previous recommendations of the Rotterdam Consensus (RC) and Androgen Excess-Polycystic Ovarian Syndrome Society (AES/PCOS) criteria. The aim of this study was to determine the prevalence of PCOM in healthy adolescents according to the 3 reported diagnostic criteria and compare the hormonal profile in females with and without PCOM based on the PedC criteria. Metho
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Murphy, M. K., J. E. Hall, J. M. Adams, H. Lee, and C. K. Welt. "Polycystic Ovarian Morphology in Normal Women Does Not Predict the Development of Polycystic Ovary Syndrome." Journal of Clinical Endocrinology & Metabolism 91, no. 10 (2006): 3878–84. http://dx.doi.org/10.1210/jc.2006-1085.

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Abstract Context: Polycystic ovarian morphology (PCOM) is present in 25% of normal women in the absence of polycystic ovary syndrome (PCOS); however, the natural history of PCOM is unknown. Objective: We hypothesized that the presence of PCOM predisposes the development of PCOS. Design: The study was a longitudinal follow-up study over 8.2 ± 5.2 yr (mean ± sd; range 1.7–17.5 yr). Setting: The study took place in an outpatient setting. Subjects: Women who took part in a previous study as a normal control and had an ultrasound examination (n = 40) participated. Intervention: Subjects underwent a
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Hidayah, Baiq Nurul, Muhammad Tahir Hamsyah, Mohammad Rani, et al. "Respons Bawang Putih pada Berbagai Frekuensi Penyemprotan Pupuk Cair Organik Mikro." Agrotechnology Research Journal 8, no. 1 (2024): 58–65. https://doi.org/10.20961/agrotechresj.v8i1.92416.

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Garlic is a horticultural commodity with high economic value in Indonesia. For optimal growth and yield, garlic plants need macro and micronutrients from fertilization. Micronutrients can be fulfilled, such as by spraying micro-organic liquid fertilizer. This research aims to determine the effect of various spraying frequencies of Micro Organic Liquid Fertilizer – Micro Magic (PCOM-MM) on the growth of garlic plants. The garlic variety planted was local Sangga Sembalun using a 1-factor Randomized Block Design with 4 treatments of spraying frequencies: 1) without spraying PCOM-MM, 2) spraying P
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Sharma, Prakash, Subita Lalchan, Subhash KC, Merina Gyawali, and Niraj Kushwaha. "Impact of gender and age on inner diameter of arteries forming circle of Willis assessed by multidetector CT." Journal of Brain and Spine Foundation Nepal 2, no. 1 (2021): 37–41. http://dx.doi.org/10.3126/jbsfn.v2i1.39016.

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Introduction: The circle of Willis (CoW), which is located at the base of the brain is the most important anastomosis between the internal carotid and vertebral system. It is the main distributor of blood to the brain. Methods: CT head and CT angiography were performed using standard scan parameters. Only the tests with normal radiological reports and appropriate technical standards were included in the study. Component of circle of Willis: Anterior cerebral artery (ACA), Middle cerebral artery (MCA), Anterior communicating artery (Acom), Posterior Communicating artery (PCom), Basilar artery (
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Lazareva, Lyudmila, and Larisa Suturina. "Polycystic Ovarian Morphology: Diagnostic Criteria and Prevalence." International Journal of Biomedicine 12, no. 1 (2022): 100–103. http://dx.doi.org/10.21103/article12(1)_ra6.

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The purpose of this brief review was to systematize the current information on the diagnosis, prevalence, and ethnic aspects of polycystic ovarian morphology (PCOM). The information search was conducted using Internet resources (Medline, Pubmed, Cochrane Library, and Google Scholar) and literature sources for the period from January 1999 to August 2021. The review includes only full-text articles. Based on the analysis of the literature, we demonstrated that the diagnostic value of PCOM has changed since the moment of the first description of polycystic ovarian syndrome (PCOS). Currently, ovar
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Reynolds, Matthew R., Jarod L. Roland, Ashwin A. Kamath, DeWitte T. Cross, and Ralph G. Dacey. "Microsurgical confirmation of perforating arteries arising from the fundus of a posterior communicating artery aneurysm." Neurosurgical Focus 39, videosuppl1 (2015): V16. http://dx.doi.org/10.3171/2015.7.focusvid.14628.

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Perforating arteries rarely project from the fundus of an aneurysm. We present the case of a 35-year-old woman who was found to have a right posterior communicating artery (PCOM) aneurysm via catheter angiography. Superselective microcatheter angiography revealed that perforating arteries arose from the aneurysm fundus that supplied the anterolateral thalamus. Microsurgical exploration confirmed several small perforating arteries arising from the aneurysm dome as well as an atretic distal PCOM artery. Given the complex anatomy, the lesion was unsuitable for clipping. We propose that this aneur
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Wongwananuruk, Thanyarat, Panicha Chantrapanichkul, Vichuta Unalome, et al. "Polycystic ovarian morphology in Thai women of reproductive age with polycystic ovary syndrome." Asian Biomedicine 14, no. 6 (2020): 271–77. http://dx.doi.org/10.1515/abm-2020-0036.

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Abstract Background Advancements in ultrasound technology have facilitated identifying polycystic ovarian morphology (PCOM) in women with and without polycystic ovary syndrome (PCOS), but it still has limitations due to follicle counting methods and variation of phenotypes according to ethnicity. Ethnicity-specific ovarian morphology may help to establish ethnicity-specific follicle count cut points for defining PCOM in women with PCOS. Objectives To investigate the prevalence and factors associated with PCOM in Thai women of a reproductive age with PCOS. Methods This prospective cross-section
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Basma, Jaafar, Kenneth A. Moore, Khaled Krisht, et al. "Morphometric Comparison of the Pterional Trans-Sylvian and the Pretemporal Trans-Clinoidal Approaches to the Posterior Communicating Artery." Operative Neurosurgery 20, no. 1 (2020): E22—E30. http://dx.doi.org/10.1093/ons/opaa261.

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Abstract BACKGROUND Posterior communicating (Pcom) aneurysms in the modern era have tended toward increased complexity and technical difficulties. The pretemporal approach is a valuable extension to the pterional approach for basilar apex aneurysms, but its advantages for Pcom aneurysms have not been previously elucidated. OBJECTIVE To quantify characteristics of the pretemporal approach to the Pcom. METHODS We dissected 6 cadaveric heads (12 sides) with a pretemporal transclinoidal approach and measured the following variables: (1) exposed length of internal carotid artery (ICA) proximal to t
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Bell, Robin J., Rakibul M. Islam, Marina A. Skiba, Dilinie Herbert, Alejandra Martinez Garcia, and Susan R. Davis. "Substituting serum anti-Müllerian hormone for polycystic ovary morphology increases the number of women diagnosed with polycystic ovary syndrome: a community-based cross-sectional study." Human Reproduction 37, no. 1 (2021): 109–18. http://dx.doi.org/10.1093/humrep/deab232.

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Abstract STUDY QUESTION Can serum anti-Müllerian hormone (AMH) replace polycystic ovary morphology (PCOM) determined by ultrasound as a diagnostic component of polycystic ovary syndrome (PCOS)? SUMMARY ANSWER Despite good correlations between serum AMH and PCOM, the use of a high serum AMH as a proxy for PCOM resulted in the reclassification of PCOS in 5% of study participants, with the main effect being more women identified, although some women previously classified as having PCOS were no longer classified as such. WHAT IS KNOWN ALREADY AMH has been proposed as an alternative to PCOM as a di
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Makolle, Sarah, Sophie Catteau-Jonard, Geoffroy Robin, and Didier Dewailly. "Revisiting the serum level of anti-Müllerian hormone in patients with functional hypothalamic anovulation." Human Reproduction 36, no. 4 (2021): 1043–51. http://dx.doi.org/10.1093/humrep/deab024.

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Abstract STUDY QUESTION Are serum levels of anti-Müllerian hormone (AMH) normal in patients with functional hypothalamic anovulation (FHA)? SUMMARY ANSWER Our study confirms that in the general FHA population, serum AMH levels are not decreased, but if patients with polycystic ovarian morphology (PCOM) are excluded, levels become significantly lower, as in other situations of gonadotropic insufficiency. WHAT IS KNOWN ALREADY In most situations of low LH (physiological, pharmacological or pathological), serum AMH levels are low. However, paradoxically, many publications have reported normal or
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Kim, Bum Joon, Seung Min Kim, Sung-ho Ahn, Dong-Wha Kang, Sun U. Kwon, and Jong S. Kim. "Lateral Thalamic Infarction and the Vascular Geometry of the Posterior Cerebral Artery." Cerebrovascular Diseases 41, no. 1-2 (2015): 8–12. http://dx.doi.org/10.1159/000439062.

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Background: The geometric properties of the parental artery affect the development of local atherosclerosis and perforator infarction. In this study, we aimed at investigating the association between vascular geometry of the posterior cerebral artery (PCA) and the development of isolated lateral thalamic infarction (LTI), the most frequent type of thalamic infarction. Methods: The geometric properties of the corresponding PCA in LTI patients were assessed and they include the diameters of the distal basilar artery (BA) and proximal PCA, distal BA - PCA angle, first PCA angle (angle between P1
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Sturiale, Carmelo Lucio, Alba Scerrati, Luca Ricciardi, et al. "Geometry and Symmetry of Willis’ Circle and Middle Cerebral Artery Aneurysms Development." Journal of Clinical Medicine 13, no. 10 (2024): 2808. http://dx.doi.org/10.3390/jcm13102808.

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Background: A relationship between the geometry and symmetry of Willis’ circle and intracranial aneurysms was reported for anterior communicating and posterior communicating (PCom) aneurysms. A similar association with the middle cerebral artery (MCA) aneurysms instead appeared weaker. Methods: We reviewed 432 patients from six Italian centers with unilateral MCA aneurysms, analyzing the relationship between the caliber and symmetry of Willis’ circle and the presence of ruptured and unruptured presentation. CT-angiograms were evaluated to assess Willis’ circle geometrical characteristics and t
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Nikbakht, Roshan, Mahvash Zargar, Farideh Moramezi, et al. "Insulin Resistance and Free Androgen as Predictors for Ovarian Hyperstimulation Syndrome in Non-PCOS Women." Hormone and Metabolic Research 52, no. 02 (2020): 104–8. http://dx.doi.org/10.1055/a-1079-5342.

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AbstractWe evaluated the effect of insulin resistance and free androgen index (FAI) in non-PCOS (polycystic ovary syndrome) infertile women following controlled ovarian hyperstimulation. A prospective study was done on 144 infertile non-PCOS women with regular menstrual cycle. At first, insulin resistance (IR), free androgen index (FAI), PCOM (polycystic ovary morphology), AFC (antral follicle count), and AMH (anti-Müllerian hormone) were assessed. The patients underwent assisted reproductive technology (ART), and then preovulatory follicles and oocytes retrieved were recorded. The variables o
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Piltonen, Terhi T., Deirdre Allegranza, Martin Hund, Katharina Buck, Johanna Sillman, and Riikka K. Arffman. "Validation of an Anti-Müllerian Hormone Cutoff for Polycystic Ovarian Morphology in the Diagnosis of Polycystic Ovary Syndrome in the HARMONIA Study: Protocol for a Prospective, Noninterventional Study." JMIR Research Protocols 13 (February 6, 2024): e48854. http://dx.doi.org/10.2196/48854.

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Background Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women and is diagnosed using the Rotterdam criteria, including diagnosis of polycystic ovarian morphology (PCOM) by transvaginal ultrasound (TVUS). Due to high cost, availability, and the impact of the operator and ultrasound equipment on the reliability of the antral follicle count (AFC) by TVUS, an unmet need exists for a diagnostic test to determine PCOM without TVUS. A strong positive correlation between elevated anti-Müllerian hormone (AMH) levels and AFCs has been demonstrated in women with PCOS.
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Tedjo, Raden Andi Ario, Subandi Subandi, Teddy Tejomukti, et al. "Posterior communicating artery aneurysm presenting as isolated oculomotor palsy: The role of rapid identification, intervention, and multidisciplinary care - A case study." Jurnal Keperawatan Padjadjaran 13, no. 1 (2025): 107–14. https://doi.org/10.24198/jkp.v13i1.2587.

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Background: Posterior communicating artery (PCOM) aneurysms are the prevalent type of aneurysm with high rupture risks. Isolated oculomotor nerve (CN III) palsy is a key symptom warranting heightened awareness in primary care. Given the need for advanced imaging, early referral is paramount. This study highlights the significance of prompt identification, targeted intervention, and comprehensive management in optimizing patient outcomes. Case: A 58-year-old woman presented with isolated CN III palsy. The patient underwent rapid referral to tertiary care with magnetic resonance angiography (MRA
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Merino, Paulina M., Ethel Codner, and Fernando Cassorla. "A rational approach to the diagnosis of polycystic ovarian syndrome during adolescence." Arquivos Brasileiros de Endocrinologia & Metabologia 55, no. 8 (2011): 590–98. http://dx.doi.org/10.1590/s0004-27302011000800013.

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Polycystic ovarian syndrome (PCOS) is a lifelong disorder characterized by hyperandrogenism and ovulatory dysfunction, with a wide spectrum of clinical symptoms and signs. Three different sets of diagnostic criteria have been established in order to define this disease in adult women, but there is controversy regarding the use of these criteria in adolescence. During puberty, the adult criteria for ovulatory dysfunction does not seem applicable, because an irregular menstrual pattern and a decreased ovulatory rate is a physiologic event during this period of life. Also, a higher prevalence of
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Yang, Yi, Yurong Cheng, Ye Yuan, Guoren Wang, Lei Chen, and Yongjiao Sun. "Privacy-preserving cooperative online matching over spatial crowdsourcing platforms." Proceedings of the VLDB Endowment 16, no. 1 (2022): 51–63. http://dx.doi.org/10.14778/3561261.3561266.

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With the continuous development of spatial crowdsourcing platform, online task assignment problem has been widely studied as a typical problem in spatial crowdsourcing. Most of the existing studies are based on a single-platform task assignment to maximize the platform's revenue. Recently, cross online task assignment has been proposed, aiming at increasing the mutual benefit through cooperations. However, existing methods fail to consider the data privacy protection in the process of cooperation and cause the leakage of sensitive data such as the location of a request and the historical data
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Zanaty, Mario, Nohra Chalouhi, Robert M. Starke, et al. "Failure of the Pipeline Embolization Device in Posterior Communicating Artery Aneurysms Associated with a Fetal Posterior Cerebral Artery." Case Reports in Vascular Medicine 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/4691275.

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The pipeline embolization device has emerged as an important endovascular option. This is in part due to safety, efficacy, and possibly the ability to shorten the operative time considerably. With this new technology, some limitations are emerging as experience accumulates. We report three cases of posterior communicating (PCOM) artery aneurysms associated with fetal posterior cerebral artery where pipeline embolization was unsuccessful in obliterating the aneurysms. PCOM artery aneurysms associated with a fetal PCA should be managed either by microsurgical clipping or coiling when feasible.
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RIEPSAMEN, Angelique H., Mark W. DONOGHOE, Inthrani R. INDRAN, et al. "Serum GDF9 and BMP15 as Markers of Ovarian Function in Healthy Women and Women with Polycystic Ovary Syndrome." Fertility & Reproduction 04, no. 03n04 (2022): 141. http://dx.doi.org/10.1142/s266131822274053x.

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Background: The oocyte-secreted factors growth differentiation factor-9 (GDF9) and bone morphogenetic protein-15 (BMP15) are key regulators of female fertility and are predominantly expressed by oocytes. Recently, methods to quantitate these proteins in serum have demonstrated diagnostic potential. It is unknown if concentrations reflect ovarian and endocrine function, particularly in women with polycystic ovary syndrome (PCOS), where GDF9/BMP15 function is suggested to be aberrant. Aim: To determine if serum GDF9/BMP15 are associated with ovarian and endocrine parameters, and the ovarian path
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Zhao, Yang, Yinlong Zhao, Chunpeng Wang, Zhenzhen Liang, and Xin Liu. "DIAGNOSTIC VALUE OF ANTI-MÜLLERIAN HORMONE AS A BIOMARKER FOR POLYCYSTIC OVARY SYNDROME: A META-ANALYSIS UPDATE." Endocrine Practice 25, no. 10 (2019): 1056–66. http://dx.doi.org/10.4158/ep-2019-0098.

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Objective: A previous meta-analysis carried out on the predictive ability of anti-Müllerian hormone (AMH) for polycystic ovary syndrome (PCOS) showed that independent AMH may be a useful initial diagnostic test for PCOS. The aims of this study were to update the meta-analysis and to evaluate the diagnostic efficacy of AMH when it replaces polycystic ovary morphology (PCOM) in the Rotterdam criteria. Methods: Two independent reviewers searched PubMed, Cochrane Library, and the Web of Science databases systematically to identify relevant articles by using the key words “anti-Müllerian hormone” a
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Mohamed Micdhadhu, Mohamed Azlam, Ko Hin Kho, Mazeda Murad, and Irene Looi. "Fetal posterior communicating artery as a conduit for concurrent anterior and posterior circulation infarct: A case report." Journal Of Cardiovascular, Neurovascular & Stroke 3, no. 4 (2021): 7–11. http://dx.doi.org/10.32896/cvns.v3n4.7-11.

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Fetal type posterior cerebral artery (FTPCA) is a variant of posterior circulation of brain, in which the distal part of posterior cerebral artery (PCA) is perfused by a branch of internal carotid artery (ICA) via fetal posterior communicating artery (fetal PCOM). In the presence of fetal PCOM, a paradoxical concurrent infarction of anterior and posterior circulation may happen. We report a 67-year-old man who presented with sudden onset right sided weakness and aphasia, with National Institutes of Health Stroke Scale (NIHSS) score of 22 and clinically diagnosed to have left total anterior cir
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Rossen, James D., Edgar A. Samaniego, Mishelle Paullus, and Santiago Ortega-Gutierrez. "Hybrid Retrograde-Antegrade Recanalization of Acute Basilar Artery Occlusion." Interventional Neurology 6, no. 3-4 (2017): 263–67. http://dx.doi.org/10.1159/000479704.

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Acute basilar artery (BA) occlusion has a very poor prognosis. Recanalization can be challenged by bilateral vertebral artery (VA) occlusions, arterial dissection, or advanced atherosclerotic disease. We describe a case in whom the BA was accessed and recanalized through a retrograde-antegrade approach from the anterior circulation using a large posterior communicating artery (PCOM). Once the BA had been crossed retrogradely through the PCOM, another microcatheter was advanced antegradely through the VA into the BA and right posterior cerebral artery using the “buddy-wire” technique. In this w
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Moon, Bo Min, Yun Sang Kim, Sun Eung Kim, Hye Gwang Mun, and Woo Sik Pae. "Reconstruction Using an Osteofasciocutaneous Fibula Free Flap for a Distal Tibial Defect in Refractory Chronic Osteomyelitis: A Case Report." Journal of Wound Management and Research 18, no. 2 (2022): 148–53. http://dx.doi.org/10.22467/jwmr.2022.01935.

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The fibular free flap (FFF) is an option used for tibial defect reconstruction in post-traumatic chronic osteomyelitis (PCOM). However, as the tibia is a weight-bearing bone, there exists a risk of compression fracture risk after FFF. This complicates reconstructing distal tibial defects adjacent to the articular cartilage. We report a successful case of reconstruction using FFF for a bone defect adjacent to the distal tibial articular surface in refractory PCOM. The patient was a 73-year-old woman with refractory PCOM in the right distal tibia secondary to a tibial fracture from a traffic acc
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Gu, Heng, Longyu Li, Bingyi Zhou, et al. "Single nucleotide polymorphisms in binding site of miRNA-135a and targeted gene IRS2 are correlated with multiple clinical features of PCOS: A study in Chinese women." Technology and Health Care 30 (March 2, 2022): 71–80. http://dx.doi.org/10.3233/thc-228007.

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BACKGROUND: The etiology of polycystic ovary syndrome (PCOS) remains unclear with highly heterogeneous clinical manifestations, recently growing evidence revealing genetic variants play a crucial part in its pathogenesis. OBJECTIVE: This study aimed to examine the correlation between SNPs in miRNA-135a’s binding site of targeted gene IRS2 and clinical manifestations of PCOS in Chinese females. METHOD: A total of 126 Chinese women with PCOS and 109 healthy women were enrolled, divided into 4 groups based on different clinical features of hyperandrogenemia (HA), insulin resistance (IR), polycyst
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Boegl, Magdalena, Didier Dewailly, Rodrig Marculescu, Johanna Steininger, Johannes Ott, and Marlene Hager. "The LH:FSH Ratio in Functional Hypothalamic Amenorrhea: An Observational Study." Journal of Clinical Medicine 13, no. 5 (2024): 1201. http://dx.doi.org/10.3390/jcm13051201.

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Background: In functional hypothalamic amenorrhea (FHA), luteinizing hormone and follicle-stimulating hormone levels show high interindividual variability, which significantly limits their diagnostic value in differentiating FHA from polycystic ovary syndrome (PCOS). Our aim was to profile the LH:FSH ratio in a large sample of patients with well-defined FHA. Methods: This observational study included all consecutive patients with FHA presenting to the Department of Gynecologic Endocrinology and Reproductive Medicine, Medical University of Vienna, between January 2017 and August 2023. The main
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Krishnan, Abhaya, Sridhar Muthusami, Loganayaki Periyasamy, Jone A. Stanley, Vasudevan Gopalakrishnan, and Ilangovan Ramachandran. "Effect of DHT-Induced Hyperandrogenism on the Pro-Inflammatory Cytokines in a Rat Model of Polycystic Ovary Morphology." Medicina 56, no. 3 (2020): 100. http://dx.doi.org/10.3390/medicina56030100.

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Background and Objectives: Polycystic ovary syndrome (PCOS) is one of the most prevalent disorders among women of reproductive age. It is considered as a pro-inflammatory state with chronic low-grade inflammation, one of the key factors contributing to the pathogenesis of this disorder. Polycystic ovary is a well-established criterion for PCOS. The present investigation aimed at finding the role of hyperandrogenism, the most important feature of PCOS, in the development of this inflammatory state. To address this problem, we adopted a model system that developed polycystic ovary morphology (PC
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Bian, Xiaohua, Yifan Cao, Ximin Zhi, and Ni Ma. "Genome-Wide Identification and Analysis of the Plant Cysteine Oxidase (PCO) Gene Family in Brassica napus and Its Role in Abiotic Stress Response." International Journal of Molecular Sciences 24, no. 14 (2023): 11242. http://dx.doi.org/10.3390/ijms241411242.

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Plant Cysteine Oxidase (PCO) is a plant O2-sensing enzyme catalyzing the oxidation of cysteine to Cys-sulfinic acid at the N-termini of target proteins. To better understand the Brassica napus PCO gene family, PCO genes in B. napus and related species were analyzed. In this study, 20, 7 and 8 PCO genes were identified in Brassica napus, Brassica rapa and Brassica oleracea, respectively. According to phylogenetic analysis, the PCOs were divided into five groups: PCO1, PCO2, PCO3, PCO4 and PCO5. Gene organization and motif distribution analysis suggested that the PCO gene family was relatively c
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KAKIZAWA, Toshiyuki, Shigeru MITSUKA, Masami KANEKO, et al. "PC-Pcom Aneurysm with Ipsilateral ICA Occlusion." Surgery for Cerebral Stroke 16, no. 1 (1988): 53–58. http://dx.doi.org/10.2335/scs1987.16.1_53.

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Balogun, Mobolanle, Olayinka Coker, Titilola Samuel, et al. "PMON245 Clinical Phenotypes of Polycystic Ovary Syndrome (PCOS) in Nigerian Women: Preliminary Results of the Nigeria PCOS Epidemiology & Phenotype (Nigeria-Pep) Study." Journal of the Endocrine Society 6, Supplement_1 (2022): A696. http://dx.doi.org/10.1210/jendso/bvac150.1436.

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Abstract Background Although the phenotype of polycystic ovary syndrome (PCOS) is heterogeneous, there is paucity of data on the prevalence and phenotype of PCOS in sub-Saharan Africa. Methods We studied 75 consecutive consenting women, aged 18-45 years, who presented with features suggestive of PCOS. A standardized proforma was used to obtain relevant information. Anthropometric measurements were determined, and terminal hair growth was assessed using the modified Ferriman-Gallwey (mF-G) method. All subjects underwent an oral glucose tolerance test (OGTT) and pelvic ultrasonography on day 2-7
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Antunes, Bárbara, Stephen Barclay, Isla Kuhn, et al. "Implementing patient-centred outcome measures in palliative care clinical practice for adults (IMPCOM): Protocol for an update systematic review of facilitators and barriers." F1000Research 12 (February 28, 2023): 224. http://dx.doi.org/10.12688/f1000research.131479.1.

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Background: Despite the development of patient-centred or patient-reported outcome measures (PCOMs or PROMs) in palliative and end-of-life care over recent years, their routine use in practice faces continuing challenges. Objective: To update a highly cited literature review, identify and synthesise new evidence on facilitators, barriers, lessons learned, PCOMs used, models of implementation, implementation outcomes, costs, and consequences of implementing PCOMs in palliative care clinical practice. Methods: We will search MEDLINE, PsycINFO, CINAHL, Embase, Emcare, SCI-Expanded, SSCI, ESCI, an
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Antunes, Bárbara, Stephen Barclay, Isla Kuhn, et al. "Implementing patient-centred outcome measures in palliative care clinical practice for adults (IMPCOM): Protocol for an update systematic review of facilitators and barriers." F1000Research 12 (October 30, 2023): 224. http://dx.doi.org/10.12688/f1000research.131479.2.

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Background: Despite the development of patient-centred or patient-reported outcome measures (PCOMs or PROMs) in palliative and end-of-life care over recent years, their routine use in practice faces continuing challenges. Objective: To update a highly cited literature review, identify and synthesise new evidence on facilitators, barriers, lessons learned, PCOMs used, models of implementation, implementation outcomes, costs, and consequences of implementing PCOMs in palliative care clinical practice. Methods: We will search MEDLINE, PsycINFO, CINAHL, Embase, Emcare, SCI-Expanded, SSCI, ESCI, an
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Lazareva, L. M., A. V. Atalyan, I. N. Danusevich, et al. "Ultrasonographic threshold of ovarian structure in premenopausal women of different ethnicity." Acta Biomedica Scientifica 9, no. 3 (2024): 49–68. http://dx.doi.org/10.29413/abs.2024-9.3.5.

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The polycystic ovarian morphology (PCOM) is a generally accepted ultrasound marker for ovulatory dysfunction, is one of the criteria for polycystic ovary syndrome (PCOS) and is established based on the assessment of ovarian volume (OV) and the follicle number per ovary (FNPO), taking into account the upper normal values determined in healthy premenopausal women. However, there is a necessity for regular revision of the PCOM characteristics depending on ethnic and age characteristics.The aim. To develop differentiated standards for assessing the ultrasonographic ovary structure in premenopausal
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Lazareva, Ludmila, Larisa Suturina, Alina Atalyan, et al. "Ovarian Morphology in Non-Hirsute, Normo-Androgenic, Eumenorrheic Premenopausal Women from a Multi-Ethnic Unselected Siberian Population." Diagnostics 14, no. 7 (2024): 673. http://dx.doi.org/10.3390/diagnostics14070673.

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Polycystic ovary syndrome (PCOS) is a highly prevalent disorder in women, and its diagnosis rests on three principal features: ovulatory/menstrual dysfunction, clinical and/or biochemical hyperandrogenism, and polycystic ovarian morphology (PCOM). Currently, data on age- and ethnicity-dependent features of PCOM remain insufficient. We aimed to estimate ethnicity- and age-dependent differences in ovarian volume (OV) and follicle number per ovary (FNPO) in a healthy, medically unbiased population of Caucasian and Asian premenopausal women, who participated in the cross-sectional Eastern Siberia
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Rogers, Patrick Scott, David Volders, Gwynedd Pickett, and Robert Vandorpe. "Coil migration through two flow-diverting stents." BMJ Case Reports 17, no. 1 (2024): e256863. http://dx.doi.org/10.1136/bcr-2023-256863.

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We report a case of a patient who initially presented with a subarachnoid haemorrhage secondary to a ruptured supraclinoid internal carotid artery (ICA) blister aneurysm. The patient was treated successfully with a flow diverter stent (FD) and coiling; however, a large aneurysm recurrence via a feeding posterior communicating artery (PCOM) was noted on the 1-year follow-up angiogram. During the retreatment, a second FD in the ICA resulted in insufficient aneurysm stasis. Therefore, the decision was made to coil sacrifice the PCOM via posterior circulation access. During the first coil deployme
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Baietto, Oliviero, and Paola Marini. "Naturally occurring asbestos: Validation of PCOM quantitative determination." Resources Policy 59 (December 2018): 44–49. http://dx.doi.org/10.1016/j.resourpol.2018.06.006.

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Robin, G., C. Gallo, S. Catteau-Jonard, et al. "Polycystic Ovary-Like Abnormalities (PCO-L) in Women with Functional Hypothalamic Amenorrhea." Journal of Clinical Endocrinology & Metabolism 97, no. 11 (2012): 4236–43. http://dx.doi.org/10.1210/jc.2012-1836.

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Context: In the general population, about 30% of asymptomatic women have polycystic ovary-like abnormalities (PCO-L), i.e. polycystic ovarian morphology (PCOM) at ultrasound and/or increased anti-Müllerian hormone (AMH) serum level. PCOM has also been reported in 30–50% of women with functional hypothalamic amenorrhea (FHA). Objective: The aim of this study was to verify whether both PCOM and excessive AMH level indicate PCO-L in FHA and to elucidate its significance. Design: We conducted a retrospective analysis using a database and comparison with a control population. Setting: Subjects rece
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Archana, Singhal. "Determination of PCOS by Assessing Anti-Mullerian Hormone." International Journal of Pharmaceutical and Clinical Research 15, no. 10 (2023): 1635–40. https://doi.org/10.5281/zenodo.11312496.

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<strong>Introduction:&nbsp;</strong>Polycystic Ovarian Syndrome&nbsp;<strong>(</strong>PCOS) affects 20.2% of pubertal women and presents differently, making diagnosis difficult. Many employ the Rotterdam criteria, which emphasise PCO morphology, hyperandrogenism, and oligo or amenorrhea. PCOS diagnosis by AMH, which measures ovarian follicle count, is promising. GnRH neurons are affected by AMH, causing PCOS. As high as 3.8&ndash;5 ng/mL, AMH levels in PCOS women may be diagnostic. AMH and Rotterdam criteria may improve PCOS diagnosis, especially in culturally diverse communities.&nbsp;<stron
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Fuentes, Lidia, Daniel Jiménez, and Mónica Pinto. "Development of Ambient Intelligence Applications using Components and Aspects." JUCS - Journal of Universal Computer Science 12, no. (3) (2006): 236–51. https://doi.org/10.3217/jucs-012-03-0236.

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In recent times, interest in Ambient Intelligence (or AmI) has increased considerably. One of the main challenges in the development of these systems is to improve their modularization in order to achieve a high degree of reusability, adaptability and extensibility. This will help us to deal with the heterogeneity and evolution of the environments in which AmI devices exit. An example would be to easily adapt existing applications when new communication technologies appear. Current approaches apply component technologies to achieve these goals, but more should be done. Our research focuses on
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Lasiste, Jade Marie, Pablo Zoroquiain, Denise Miyamoto, and Miguel Burnier. "Metformin activity in an in vitro model of posterior capsule opacification." Vision Pan-America, The Pan-American Journal of Ophthalmology 17, no. 4 (2018): 105–12. http://dx.doi.org/10.15234/vpa.v17i4.511.

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Purpose: To determine the activity of metformin in an in vitro model of posterior capsule opacification (PCO).Design: Experimental laboratory research. Methods: The HLE-B3 lens epithelial cell line was treated with PCO induction media (PCOM) supplemented with transforming growth factor-beta (TGF-β) and fibroblast growth factor (FGF). Different metformin concentrations (0-100 mM) were used. The following cellular parameters were assessed: (1) survival, using a viability assay; (2) morphology, via microscopy and image analysis; (3) migration, using the wound assay; (4) and expression of epitheli
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Alamoudi, Abrar, Irfan Ullah Khan, Nida Aslam, et al. "A Deep Learning Fusion Approach to Diagnosis the Polycystic Ovary Syndrome (PCOS)." Applied Computational Intelligence and Soft Computing 2023 (February 14, 2023): 1–15. http://dx.doi.org/10.1155/2023/9686697.

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One of the leading causes of female infertility is PCOS, which is a hormonal disorder affecting women of childbearing age. The common symptoms of PCOS include increased acne, irregular period, increase in body hair, and overweight. Early diagnosis of PCOS is essential to manage the symptoms and reduce the associated health risks. Nonetheless, the diagnosis is based on Rotterdam criteria, including a high level of androgen hormones, ovulation failure, and polycystic ovaries on the ultrasound image (PCOM). At present, doctors and radiologists manually perform PCOM detection using ovary ultrasoun
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Körpe, Büşra, Samet Kutluay Ergörün, Sümeyye Mermi, and Caner Kose. "The Impact of Polycystic Ovary Syndrome on Tubal Ectopic Pregnancy Risk During First Pregnancy." Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 22, no. 1 (2025): 69–74. https://doi.org/10.38136/jgon.1604251.

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Aim: This study aimed to investigate the effect of Polycystic Ovary Syndrome (PCOS) on the risk of tubal ectopic pregnancy during first pregnancy and how this risk varies across different PCOS phenotypes. Materials and Methods: This retrospective study analyzed 657 women diagnosed with ectopic pregnancy between November 2022 and November 2024 at a tertiary care hospital. Of these, 222 women had confirmed tubal ectopic pregnancies and a documented diagnosis of PCOS at the same center. The participants were divided into two groups based on the Rotterdam criteria: PCOS (n=76) and non-PCOS (n=146)
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MacLean, MA, T. Huynh, M. Schmidt, VM Pereira, and A. Weeks. "P.193 Competitive Flow Diversion: Proposed Classification System." Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 48, s3 (2021): S76. http://dx.doi.org/10.1017/cjn.2021.469.

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Background: Competitive flow diversion (CFD) is a novel application of flow diversion stenting (FDS), redirecting flow into a normal artery proximal or distal to the aneurysmal parent artery. A classification system for CFD has not been previously reported. Methods: Report of operative technique and novel classification system for CFD. Results: A patient with subarachnoid haemorrhage and three aneurysms arising from the Pcomm-P1 complex, was treated with endovascular coiling and CFD. The PCOM aneurysm was coiled. Two aneurysms arose from the distal right P1- PCA. After a failed attempt to trea
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Baş, Hakan, and Süleyman Filiz. "Evaluation of Ovarian Stromal Microvascularity and Clinical-Hormonal Associations in Reproductive-Aged Women with Polycystic Ovary Morphology." Diagnostics 15, no. 11 (2025): 1376. https://doi.org/10.3390/diagnostics15111376.

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Background/Objectives: This study aims to assess ovarian stromal vascularity using microvascular imaging in reproductive-aged women with polycystic ovarian morphology (PCOM) and to explore its associations with endocrine parameters and polycystic ovary syndrome (PCOS) phenotypes. Methods: We conducted a retrospective, single-center study between January 2021 and November 2023. Women aged 18–49 who met the PCOM criteria (≥20 follicles measuring 2–9 mm or an ovarian volume &gt;10 cm3 in at least one ovary) were included. Pelvic ultrasound with MV-Flow Doppler imaging was used to quantify the str
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Langenau, Erik, Sarah B. Frank, Sarah J. Calardo, and Michael B. Roberts. "Survey of Osteopathic Medical Students Regarding Physician Shadowing Experiences Before and During Medical School Training." Journal of Medical Education and Curricular Development 6 (January 2019): 238212051985204. http://dx.doi.org/10.1177/2382120519852046.

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Introduction: Shadowing a physician is an observational experience which includes a student observing a licensed healthcare provider caring for patients. Shadowing is commonly done by students before and during medical school, but little is known about the nature or extent of these extra-curricular observational experiences. Objective: We hypothesized that shadowing experiences were common yet variable. We investigated the prevalence, nature, and perceived value of medical student experiences with shadowing physicians (both before and during medical school). Methods: This survey-based study wa
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Aljammal, Diana Sulieman, Shefaa Saleh Almashaqbeh, Hend Moqbel Harahsheh, Rana Ahmed Alkrimeen, and Rawan Nahed Hiyari. "Using Ultrasound in the Confirmation of Polycystic Ovary Syndrome." SAS Journal of Medicine 8, no. 8 (2022): 528–32. http://dx.doi.org/10.36347/sasjm.2022.v08i08.003.

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Background: Polycystic ovary syndrome (PCOS) is found in 6–15% of females of reproductive age (1, 2) with polycystic ovaries on pelvic ultrasonography. Polycystic ovaries are nonspecific on ultrasound, overlapping with findings in 40% of people who do not have the syndrome. Aim: To assess the advantages of transabdominal pelvic ultrasound in the confirmation of PCOS. Methods: This prospective investigation compared 45 female participants with PCOS, average age 14.9 years (group I) with 82 female participants with acute appendicitis, average age 14.3 years (group II), at Hashim Bin Al-hussein M
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Puri, A. S., and E. Erdem. "Unusual Intracranial Stent Navigation through the Circle of Willis in a Patient with Recurrent Basilar Tip Aneurysm during Stent-Assisted Coiling." Interventional Neuroradiology 15, no. 1 (2009): 81–86. http://dx.doi.org/10.1177/159101990901500113.

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We describe a case of unusual Enterprise stent navigation through the Circle of Willis in a patient with a basilar tip aneurysm, left internal carotid artery (ICA) occlusion and previous right ICA stenting. Basilar tip aneurysms are known for their therapeutic challenges, especially when the posterior cerebral arteries (PCAs) are incorporated in the aneurysm neck. This becomes more technically demanding if the vertebral artery does not offer a route for stent navigation. We undertook stent-assisted coiling using the horizontal stenting of posterior cerebral arteries via both the posterior and
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Gupta, Neha, Uma Pandey, Shivi Jain, and Surya Kumar Singh. "Role of anti mullerian hormone (AMH) in diagnosis of polycystic ovarian syndrome (PCOS) in Indian women." Indian Journal of Obstetrics and Gynecology Research 10, no. 3 (2023): 294–98. http://dx.doi.org/10.18231/j.ijogr.2023.060.

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: Transvaginal ultrasound is an important part of the Rotterdam criteria, which are commonly used to diagnose polycystic ovary syndrome (PCOS). Specifically, the presence of polycystic ovarian morphology (PCOM) is a key factor in the criteria. Another useful indicator of PCOM is the Anti-Mullerian hormone (AMH) level.The objective is to evaluate the diagnostic accuracy of serum Anti-Mullerian hormone (AMH) in identifying polycystic ovary syndrome (PCOS) and determine whether it can be used as a substitute for polycystic ovarian morphology (PCOM) in the Rotterdam criteria. Additionally, we aim
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