Relevant bibliographies by topics / Pcpe

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  2. Dissertations / Theses
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  5. Conference papers
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Academic literature on the topic 'Pcpe'

Author: Grafiati
Published: 4 June 2021
Last updated: 17 February 2022

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Journal articles on the topic "Pcpe"

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Cai, Mian, and Luying Xun. "Organization and Regulation of Pentachlorophenol-Degrading Genes in Sphingobium chlorophenolicum ATCC 39723." Journal of Bacteriology 184, no. 17 (September 1, 2002): 4672–80. http://dx.doi.org/10.1128/jb.184.17.4672-4680.2002.

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ABSTRACT The first three enzymes of the pentachlorophenol (PCP) degradation pathway in Sphingobium chlorophenolicum (formerly Sphingomonas chlorophenolica) ATCC 39723 have been characterized, and the corresponding genes, pcpA, pcpB, and pcpC, have been individually cloned and sequenced. To search for new genes involved in PCP degradation and map the physical locations of the pcp genes, a 24-kb fragment containing pcpA and pcpC was completely sequenced. A putative LysR-type transcriptional regulator gene, pcpM, and a maleylacetate reductase gene, pcpE, were identified upstream of pcpA. pcpE was found to play a role in PCP degradation. pcpB was not found on the 24-kb fragment. The four gene products PcpB, PcpC, PcpA, and PcpE were responsible for the metabolism of PCP to 3-oxoadipate in ATCC 39723, and inactivational mutation of each gene disrupted the degradation pathway. The organization of the pcp genes is unusual because the four PCP-degrading genes, pcpA, pcpB, pcpC, and pcpE, were found to be located at four discrete locations. Two hypothetical LysR-type regulator genes, pcpM and pcpR, have been identified; pcpM was not required, but pcpR was essential for the induction of pcpB, pcpA, and pcpE. The coinducers of PcpR were PCP and other polychlorinated phenols. The expression of pcpC was constitutive. Thus, the organization and regulation of the genes involved in PCP degradation to 3-oxoadipate were documented.
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Steiglitz, Barry M., Douglas R. Keene, and Daniel S. Greenspan. "PCOLCE2Encodes a Functional Procollagen C-Proteinase Enhancer (PCPE2) That Is a Collagen-binding Protein Differing in Distribution of Expression and Post-translational Modification from the Previously Described PCPE1." Journal of Biological Chemistry 277, no. 51 (October 20, 2002): 49820–30. http://dx.doi.org/10.1074/jbc.m209891200.

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The procollagen COOH-terminal proteinase enhancer (PCPE) is a glycoprotein that binds the COOH-terminal propeptide of type I procollagen and potentiates its cleavage by procollagen C-proteinases, such as bone morphogenetic protein-1 (BMP-1). Recently, sequencing of a human expressed sequence tag, which maps near the primary open angle glaucoma region on chromosome 3q21, showed it to encode a novel protein with only 43% identity with PCPE but with a similar domain structure. Here we show this novel protein to be a functional procollagen COOH-terminal proteinase enhancer with activity comparable with that of PCPE and thus propose the designations PCPE2 and PCPE1, respectively. PCPE2 is shown to have a much more limited distribution of expression than does PCPE1, with strong expression primarily in nonossified cartilage in developing tissues and at high levels in the adult heart. PCPE2 is shown to be a glycoprotein that differs markedly in the nature of its glycosylation from that of PCPE1. PCPE2 is also shown to have markedly stronger affinity for heparin than PCPE1, which may account for higher affinities for cell layers. Unexpectedly, both PCPE1 and PCPE2 were found to be collagen-binding proteins, capable of binding at multiple sites on the triple helical portions of fibrillar collagens and also capable of competing for such binding with procollagen C-proteinases. The latter observations may provide insights into the ways PCPEs affect the kinetics of the C-proteinase reaction and into the physical interactions that occur between procollagen C-proteinases and their substrates.
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Huelsman, L. P. "The PCPE CD-ROM." IEEE Circuits and Devices Magazine 22, no. 4 (July 2006): 3–38. http://dx.doi.org/10.1109/mcd.2006.1708368.

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Zhu, He, and Changcheng Huang. "IoT-B&B: Edge-Based NFV for IoT Devices with CPE Crowdsourcing." Wireless Communications and Mobile Computing 2018 (2018): 1–15. http://dx.doi.org/10.1155/2018/3027269.

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For embracing the ubiquitous Internet-of-Things (IoT) devices, edge computing and Network Function Virtualization (NFV) have been enabled in branch offices and homes in the form of virtual Customer-Premises Equipment (vCPE). A Service Provider (SP) deploys vCPE instances as Virtual Network Functions (VNFs) on top of generic physical Customer-Premises Equipment (pCPE) to ease administration. Upon a usage surge of IoT devices at a certain part of the network, vCPU, memory, and other resource limitations of a single pCPE node make it difficult to add new services handling the high demand. In this paper, we present IoT-B&B, a novel architecture featuring resource sharing of pCPE nodes. When a pCPE node has sharable resources available, the SP will utilize its free resources as a “bed-and-breakfast” place to deploy vCPE instances in need. A placement algorithm is also presented to assign vCPE instances to a cost-efficient pCPE node. By keeping vCPE instances at the network edge, their costs of hosting are reduced. Meanwhile, the transmission latencies are maintained at acceptable levels for processing real-time data burst from IoT devices. The traffic load to the remote, centralized cloud can be substantially reduced.
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Tessier, Agnès, Sandrine Vadon-Le Goff, Leena Bruckner-Tuderman, Alexander Nyström, and Catherine Moali. "Fonctions divergentes des « Procollagen C-Proteinase Enhancers », PCPE-1 et PCPE-2, dans la cicatrisation cutanée." Annales de Dermatologie et de Vénéréologie 143, no. 12 (December 2016): S430. http://dx.doi.org/10.1016/j.annder.2016.09.076.

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Potthoff, Bojarski, Kohut, Lipska, Liwo, Kessler, Ricard-Blum, and Samsonov. "Analysis of Procollagen C-Proteinase Enhancer-1/Glycosaminoglycan Binding Sites and of the Potential Role of Calcium Ions in the Interaction." International Journal of Molecular Sciences 20, no. 20 (October 10, 2019): 5021. http://dx.doi.org/10.3390/ijms20205021.

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In this study, we characterize the interactions between the extracellular matrix protein, procollagen C-proteinase enhancer-1 (PCPE-1), and glycosaminoglycans (GAGs), which are linear anionic periodic polysaccharides. We applied molecular modeling approaches to build a structural model of full-length PCPE-1, which is not experimentally available, to predict GAG binding poses for various GAG lengths, types and sulfation patterns, and to determine the effect of calcium ions on the binding. The computational data are analyzed and discussed in the context of the experimental results previously obtained using surface plasmon resonance binding assays. We also provide experimental data on PCPE-1/GAG interactions obtained using inhibition assays with GAG oligosaccharides ranging from disaccharides to octadecasaccharides. Our results predict the localization of GAG-binding sites at the amino acid residue level onto PCPE-1 and is the first attempt to describe the effects of ions on protein-GAG binding using modeling approaches. In addition, this study allows us to get deeper insights into the in silico methodology challenges and limitations when applied to GAG-protein interactions.
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Coeler, Matthias, Vanessa van Laack, Frederieke Langer, Annegret Potthoff, Sören Höhn, Sebastian Reuber, Katharina Koscheck, and Mareike Wolter. "Infiltrated and Isostatic Laminated NCM and LTO Electrodes with Plastic Crystal Electrolyte Based on Succinonitrile for Lithium-Ion Solid State Batteries." Batteries 7, no. 1 (February 3, 2021): 11. http://dx.doi.org/10.3390/batteries7010011.

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We report a new process technique for electrode manufacturing for all solid-state batteries. Porous electrodes are manufactured by a tape casting process and subsequently infiltrated by a plastic crystal polymer electrolyte (PCPE). With a following isostatic lamination process, the PCPE was further integrated deeply into the porous electrode layer, forming a composite electrode. The PCPE comprises the plastic crystal succinonitrile (SN), lithium conductive salt LiTFSI and polyacrylonitrile (PAN) and exhibits suitable thermal, rheological (ƞ = 0.6 Pa s @ 80 °C 1 s−1) and electrochemical properties (σ > 10−4 S/cm @ 45 °C). We detected a lowered porosity of infiltrated and laminated electrodes through Hg porosimetry, showing a reduction from 25.6% to 2.6% (NCM infiltrated to laminated) and 32.9% to 4.0% (LTO infiltrated to laminated). Infiltration of PCPE into the electrodes was further verified by FESEM images and EDS mapping of sulfur content of the conductive salt. Cycling tests of full cells with NCM and LTO electrodes with PCPE separator at 45 °C showed up to 165 mAh/g at 0.03C over 20 cycles, which is about 97% of the total usable LTO capacity with a coulomb efficiency of between 98 and 99%. Cycling tests at 0.1C showed a capacity of ~128 mAh/g after 40 cycles. The C-rate of 0.2C showed a mean capacity of 127 mAh/g. In summary, we could manufacture full cells using a plastic crystal polymer electrolyte suitable for NCM and LTO active material, which is easily to be integrated into porous electrodes and which is being able to be used in future cell concepts like bipolar stacked cells.
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Astakhov, Evgeny. "«Eurocommunism» and the split of the Communist movement in Spain." Cuadernos Iberoamericanos, no. 4 (December 28, 2017): 7–15. http://dx.doi.org/10.46272/2409-3416-2017-4-7-15.

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In the period post Franco were created more favorable conditions for left parties, first of all for Communist party. However, «eurocommunists» leadership of the Communist party of Spain (KPI) led her to a deep crisis. The creation in January 1984 of the new Communist party of the people of Spain (PCPE), despite the difficulties of institutional development, the complicated financial situation, lack of personnel, became a significant factor in the national political field. After many years of political and ideological disarmament of the left forces in Spain appeared a party, acting with genuine class positions. At the same time, PCPE played the role of catalyst of processes oriented to shift to the left axis of the political life of the country. However, the current situation in the Spanish communist movement, the whole objective situation in Spain dictated the need for the unification of the communists. That goal was answered by the creation of a left electoral coalition «United left».
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Weiss, Tali, Marina Brusel, Patricia Rousselle, and Efrat Kessler. "The NTR domain of procollagen C-proteinase enhancer-1 (PCPE-1) mediates PCPE-1 binding to syndecans-1, -2 and -4 as well as fibronectin." International Journal of Biochemistry & Cell Biology 57 (December 2014): 45–53. http://dx.doi.org/10.1016/j.biocel.2014.09.023.

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Chen, Li, Yimei Zhao, Xinyu Sun, Jun Jiang, Fengshou Wu, and Kai Wang. "Synthesis, singlet oxygen generation and DNA photocleavage of β,β′-conjugated polycationic porphyrins." Journal of Porphyrins and Phthalocyanines 23, no. 06 (May 28, 2019): 655–63. http://dx.doi.org/10.1142/s1088424619500378.

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In this paper, three [Formula: see text],[Formula: see text]-conjugated cationic porphyrin compounds were designed and synthesized. The structure of the intermediates and desired porphyrins were confirmed by UV, IR, 1H NMR, MS and elemental analysis. The interaction modes between these porphyrins and ct-DNA were studied by UV-vis spectroscopy and fluorescence emission spectroscopy. The results showed that PCP 1 had an external binding mode with DNA at low DNA concentration and could intercalate DNA with the increase of concentration. PCP 2 interacted with DNA through an external binding mode, and PCP 3 could insert into DNA. The binding constants ([Formula: see text] between PCP1[Formula: see text]PCP3 and ct-DNA were calculated to be 8.41 × 104, 7.33 × 104 and 4.14 × 104 M[Formula: see text], respectively. The singlet oxygen (1O[Formula: see text] generation of PCP1[Formula: see text]PCP3 was determined by the 1,3-diphenylisobenzofuran (DPBF) method using tetrapyridylporphyrin (H2TMPyP) as a reference. The 1O2 generation rate of PCP1[Formula: see text]PCP3 followed the order of PCP2 >PCP1>H2TMPyP >PCP3. Subsequently, the photocleavage effect of porphyrins on pBR322 plasmid DNA was studied by gel electrophoresis. At 10.0 [Formula: see text]M, PCP1 and PCP2 could cleave DNA completely. At 2.0 [Formula: see text]M, the cleavage rate of DNA by PCP3 was 57.5%, which was significantly higher than that of H2TMPyP (38.8%). These results verified that the amount of cationic ions in the porphyrin structure could affect the binding modes of porphyrins with DNA and their cleavage ability of DNA.
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Dissertations / Theses on the topic "Pcpe"

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Massoudi, Dawiyat. "Approches thérapeutiques des opacités cornéennes par modulation de l'activité de protéinases de la matrice extracellulaire." Toulouse 3, 2001. http://thesesups.ups-tlse.fr/1640/.

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Pour l'être vivant, la vision constitue un élément important pour la perception de l'environnement. Cette fonction peut être altérée par une perte de transparence de la cornée pouvant conduire à une cécité. Les cécités causées par une perte de transparence cornéenne constituent selon l'Organisation Mondiale de la Santé la 3ème cause de cécité dans le monde après la cataracte et le glaucome. Le seul traitement curatif qui existe à l'heure actuelle pour ce type de cécité est la greffe de cornée. Ce traitement bien que satisfaisant demeure imparfait car il se heurte à de nombreuses complications telles que le rejet de greffe. De ce fait, ce travail vise à étudier des solutions alternatives aux greffes de cornée dans le cadre du traitement des opacités cornéennes et comporte deux axes : Un axe thérapeutique qui évalue l'efficacité de protéinases dans la résorption de l'opacité cornéenne. Les études menées au cours de cette thèse ont montré que la surexpression de la MMP-14 par les kératocytes via un vecteur parvoviral induisait une diminution de la sévérité de l'opacité cornéenne installée après traumatisme. Une autre partie de ses travaux a également montré que les protéinases Tolloïdes et leurs activateurs PCPEs (Procollagen C-proteinase enhancer), protéines qui interviennent dans la maturation du collagène joueraient un rôle important dans la cicatrisation cornéenne notamment dans la régénération de la lame basale et pourraient ainsi constituer une cible thérapeutique pertinente. Un axe plus fondamental qui porte sur l'étude de l'implication des collagènes de type XII et de type XIV dans la mise en place et le maintien de l'opacité cornéenne après blessure. Ces molécules font partie des collagènes FACIT (Fibril Associated Collagens with Interrupted Triple helices). Les investigations entreprises lors de cette étude ont montré que l'expression du collagène de type XII augmente au niveau de la cornée après un traumatisme. De manière intéressante, cet accroissement ne s'observe que dans les zones de la cornée où de l'opacité s'est installée. Cette remarque, d'abord effectuée chez l'homme s'avère également valable chez la souris. De plus, des analyses plus poussées de cette protéine réalisées chez la souris ont montré une expression qui varie en fonction du degré d'opacification de la cornée. En d'autres termes, plus l'opacité de la cornée est sévère, plus l'expression du collagène de type XII est importante. Ceci laisse donc supposer que cette molécule jouerait un rôle important dans le maintien de l'opacité au niveau de la cornée. En conclusion, ce travail de thèse a permis de démontrer d'une part, l'intérêt de la modulation de métalloprotéinases dans la résorption de l'opacité cornéenne et d'autre part, l'implication du collagène FACIT de type XII dans le maintien de l'opacité mise en place après un traumatisme cornéen
Vision constitutes an important element for our perception of the environment. Visual quality can be altered by loss of corneal transparency that can lead to corneal blindness. Loss of corneal transparency represents the 3rd cause of blindness worldwide according to World Health Organization. The only current curative treatment for this type of blindness is corneal transplantation. However, this treatment although satisfactory, faces many complications such as graft rejection. Thus, the purpose of this work was to study alternatives to corneal transplantation in the treatment of corneal opacities. The work consists of two majors goals: A therapeutic axis: This first aim concerns the evaluation of the effectiveness of the modulation of metalloproteinase activity in the resorption of corneal opacity. This project included the examination of the overexpression of the matrix metalloproteinase (MMP) 14 in in vivo mouse corneal scarring. The results showed a decrease of corneal opacity following over expression of MMP14 in the corneal stroma. This project also assessed the variation in the expression of Tolloid proteinases and their enhancers PCPEs (Procollagen C-Proteinase Enhancers) during in vivo corneal wound healing. We observed a significant increase in these proteinases following corneal incision. These observations suggest that these proteinases could play an important role in corneal matrix remodeling observed during wound healing. A more fundamental axis: The purpose of this project was to investigate the implication of FACIT (Fibril Associated Collagens with Interrupted Triple helices) type XII and type XIV collagens in the establishment and maintenance of corneal opacity after injury. We observed an increase in expression of type XII collagen in the cornea after injury, more precisely where opacities persisted. This was demonstrated not only in human corneas, but also in a mouse corneal scarring model. Furthermore, the expression of type XII collagen changed according to the degree of corneal opacity. These results suggest that the type XII collagen molecule could be important in the development and the maintenance of corneal opacity after injury. In conclusion, these projects have demonstrated a novel significance in the modulation of metalloproteinase activity in the resorption of corneal opacity and the implication of the FACIT type XII collagen in the maintenance of opacity after corneal trauma
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Liu, Yiding. "Technologies for Proteomic and Genomic Biomarker Analysis." Cleveland State University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=csu1229461302.

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Harsha, Prahladh 1976. "Robust PCPs of proximity and shorter PCPs." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/26720.

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Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004.
This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Includes bibliographical references (p. 179-185).
by Prahladh Harsha.
Ph.D.
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Dalas, Florent. "Influence des paramètres structuraux de superplastifiants sur l'hydratation, la création de surfaces initiales et la fluidité de systèmes cimentaires modèles." Thesis, Dijon, 2014. http://www.theses.fr/2014DIJOS019/document.

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L’emploi d’adjuvants fluidifiants est courant pour tout béton. Ceci permet d’améliorer les propriétés rhéologiques à l’état frais: la fluidité initiale et son maintien pendant les 2-3 premières heures de la vie d’un béton. La compréhension de ce mécanisme d’action est encore partielle pour les PCP (copolymères greffés). Ici, le but a été de tester l’hypothèse selon laquelle l’évolution de la quantité de PCP adsorbé par unité de surface minérale instantanée explique quantitativement l’évolution temporelle de la fluidité au cours de la période d’ouvrabilité.Sur un système inerte (calcite), nous avons confirmé que la fluidité est bien gouvernée par l’adsorption: à même adsorption surfacique, la fluidité de la pâte est quasiment identique quelle que soit la structure du PCP. Par ailleurs sur un système inerte (calcite ou ettringite), la modification de la fonction ionique du PCP fournit une solution pour améliorer la résistance de l’adsorption à la variation de la concentration en sulfates.Deux techniques ont été utilisées pour mesurer l’aire interfaciale au cours de l’hydratation d’un système réactif modèle (aluminate tricalcique, gypse, hémihydrate et calcite): l’adsorption de N2 et la relaxométrie du proton de l’eau. L’adsorption du PCP par unité de surface réelle a été calculée et corrélée à la fluidité de la pâte. La relation simple fluidité/adsorption n’est plus vérifiée ici. La présence de PCP a un impact sur l’hydratation du système et l’augmentation de l’étendue de la surface minérale associée. Les PCP vont augmenter la surface spécifique de l’ettringite qui précipite en modifiant sa morphologie. Cet effet est plus marqué quand la densité de greffage du PCP diminue
Nowadays the use of superplasticizers admixtures becomes unavoidable for concrete. It allows enhancing the rheological properties at the fresh state: the initial flow and slump retention during the 2-3 first hours of the life of a concrete. The understanding of this mechanism is still partly elucidated for PCE (grafted copolymers). The aim of this thesis was to challenge the assumption of the evolution of the adsorbed amount of PCE per instantaneous mineral surface unit as origin of the fluidity temporal evolution during the workability period.On an inert system (calcite), we confirmed that the fluidity is mainly governed by the adsorption level. Thus for a same surface adsorption density, the fluidity of the paste is roughly similar whatever the structure of the PCE. On an inert system also (calcite or ettringite), the modification of the anionic function provides a technological way to improve the resistance of the adsorption against the variation of the sulfate ions concentration.The surface area of a reactive model system (tricalcium aluminate, gypsum, hemihydrate and calcite) has been measured by two techniques during the workability period: the N2 adsorption (BET) and the water proton relaxometry (RMN). The PCE adsorption per surface unit has been calculated and analysed in link with the fluidity of the paste. In that case, the simple relation, shown on the inert system, is not verified because the presence of PCE has also an impact on the hydration and on the extent of the surface area. Especially PCE lead to increase the surface by changing the morphology of ettringite. The specific surface area of ettringite increases when the grafting density of PCE decreases
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Harsha, Prahladh 1976. "Small PCPs with low query complexity." Thesis, Massachusetts Institute of Technology, 2000. http://hdl.handle.net/1721.1/86448.

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Šnédarová, Gabriela. "Sorpce PCP na lignitu." Master's thesis, Vysoké učení technické v Brně. Fakulta chemická, 2008. http://www.nusl.cz/ntk/nusl-216404.

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Within the framework of this diploma thesis, the sorptive capability of a lignite as a natural adsorbent was applied on an aqueous solution of pentachlorophenol. The aqueous solution of this substance, which is very dangerous for the environment, was prepared in various concentration ranges according to reached solubility. The solubility is noticed in different literatures variously and then is not applicable. That is why it was necessary to find out the ”real“ solubility. The aqueous solution of pentachlorophenol of given concentration was subsequently put to adsorption with exactly defined quantity of the lignite and as a result the adsorptive isotherms were obtained. These isotherms represent the adsorption capability in dependence on the adsorption duration, quantity of used lignite and concentration of pentachlorophenol solution. By the adsorption with duration longer than one hour, the quantity of adsorbed PCP does not increase markedly.
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Vyas, Nikhil S. M. Massachusetts Institute of Technology. "Imperfect gaps in Gap-ETH and PCPs." Thesis, Massachusetts Institute of Technology, 2019. https://hdl.handle.net/1721.1/122771.

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Thesis: S.M., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2019
Cataloged from PDF version of thesis.
Includes bibliographical references (pages 45-47).
In this thesis we study the role of perfect completeness in probabilistically checkable proof systems (PCPs) and give a new way to transform a PCP with imperfect completeness to a PCP with perfect completeness, when the initial gap is a constant. In particular, we show that PCP[subscript c,s][r, q] [mathematical symbol] PCP[subscript 1,s'][r + 0(1), q+ 0 (r)] for c - s = [omega](1) which in turn implies that one can convert imperfect completeness to perfect in linear-sized PCPs for NTIME[0(n)] with a 0(log n) additive loss in the query complexity q. We show our result by constructing a "robust circuit" using threshold gates. These results are a gap amplification procedure for PCPs (when completeness is imperfect), analogous to questions studied in parallel repetition [21] and pseudorandomness [141. We also investigate the time complexity of approximating perfectly satisfiable instances of 3SAT versus those with imperfect completeness. We show that the Gap-ETH conjecture without perfect completeness is equivalent to Gap-ETH with perfect completeness; that is, MAX 3SAT(1 - [epsilon], 1 - [delta]) for [delta] > [epsilon] has 2⁰([superscript n])-time algorithms if and only if MAX 3SAT(1, 1 - [delta]) has 2⁰([superscript n])-time algorithms. We also relate the time complexities of these two problems in a more fine-grained way, to show that T₂ (n) by Nikhil Vyas.
S.M.
S.M. Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science
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Drucker, Andrew Donald. "PCPs for Arthur-Merlin games and communication protocols." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/60160.

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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2010.
Includes bibliographical references (p. 59-62).
Probabilistically Checkable Proofs (PCPs) are an important class of proof systems that have played a key role in computational complexity theory. In this thesis we study the power of PCPs in two new settings: Arthur-Merlin games and communication protocols. In the first part of the thesis, we give a 'PCP characterization' of AM analogous to the PCP Theorem for NP. Similar characterizations have been given for higher levels of the Polynomial Hierarchy, and for PSPACE; however, we suggest that the result for AM might be of particular significance for attempts to derandomnize this class. To test this notion, we pose some 'Randomized Optimization Hypotheses' related to our stochastic CSPs that (in light of our result) would imply collapse results for AM. Unfortunately, the hypotheses appear over-strong, and we present evidence against them. In the process we show that. if some language in NP is hard-on-average against circuits of size 2 [omega](n), en there exist hard-on-average optimization problems of a particularly elegant form. In the second part of the thesis, we study PCPs in the setting of communication protocols. Using techniques inspired by Dinur's proof of the PCP Theorem. we show that functions f (X, y) with nondeterministic circuits of size i have -distributed PCP protocols' of proof length O(poly(m)) in which each verifier looks at a constant number of proof positions. We show a complementary negative result: a distributed PCP protocol using a proof of length f, in which Alice and Bob look at k bits of the proof while exchanging t bits of communication, can be converted into a PCP-free randomized protocol with communication bounded by In both parts of the thesis, our proofs make use of a powerful form of PCPs known as Probabilistically Checkable Proofs of Proximity. and demonstrate their versatility. In our work on Arthur-Merlin games, we also use known results on randomness-efficient soundness- and hardness-amplification. In particular, we make essential use of the Impagliazzo-Wigderson generator; our analysis relies on a recent Chernoff-type theorem for expander walks.
by Andrew Donald Drucker.
S.M.
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Giese, Arnaud. "Régulation de la protéine centrale de la polarité planaire cellulaire Vangl2 dans l’organe de Corti." Thesis, Bordeaux 2, 2010. http://www.theses.fr/2010BOR21761/document.

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Outre leur polarité apico-basale, certaines cellules épithéliales développent une seconde polarité, appelée Polarité Planaire Cellulaire (PCP). L'axe de la PCP est orienté perpendiculairement à l'axe de polarité apico-basale et régit l'orientation uniforme de certaines structures, comme les poils ou cils, non seulement à l'échelle de la cellule mais également au sein du tissu. L'épithélium cochléaire est l'un des meilleurs modèles d'étude de PCP chez les mammifères. En effet, les cellules neuro-épitheliales qui le composent, soutenues par des cellules de soutien, présentent à leur apex, des touffes ciliaires dont l'orientation est parfaitement coordonnée par la voie de la polarité planaire. Les deux premiers gènes impliqués dans la PCP chez les mammifères, Vangl2 et Scrib1, ont été identifiés sur la base du phénotype de la cochlée chez les mutants. L'analyse de la localisation de Vangl2 dans l'organe de Corti a également révélé une localisation asymétrique proximo-distale et transitoire de la protéine, perpendiculaire à l'axe apico-basal classique. Cette asymétrie apparaît à la jonction entre deux types cellulaires : une cellule sensorielle ciliée et une cellule de soutien. J'ai pu montrer au cours de mes travaux de thèse que cette asymétrie était majoritairement due à une accumulation de Vangl2 du côté distal des cellules de soutien, et que dans une moindre mesure, Vangl2 pouvait ségréger du côté distal des cellules ciliées. Cette localisation subcellulaire très précise et limitée dans l'espace semble être indépendante de l'expression du gène Scrib1 dans les cellules ciliées. La délétion du gène Scrib1 dans les cellules ciliées m'a toutefois permis de mettre en évidence que ce gène avait un rôle autonome dans la régulation de la PCP, et que les cellules de soutien de l'organe de Corti pouvaient jouer un rôle prépondérant dans le contrôle de la PCP. Mes travaux ont également permis de mettre en évidence que GIPC1 avait un rôle dans la régulation de la PCP et le maintien de l'intégrité des touffes ciliaires des cellules sensorielles, et que le complexe GIPC1/Myosine VI pouvait réguler l'établissement de l'asymétrie de Vangl2 dans l'organe de Corti
Several epithelia exhibit a second polarity perpendicular to the apico-basal axis, called planar polarity and that governs the orientation of structures such as stereocilia and hear. Our laboratory studies planar polarity, using mammalian cochlear sensory epithelium and we focus our studies on Vangl2, that we identified as the first mammalian planar polarity gene. Vangl2 encodes a four-transmembrane protein that contains a PDZ binding domain in its C-terminus tail. Vangl2 is asymmetrically located at the junction between mechanosensory hair cells and supporting cells, and this asymmetry appears important for planar cell polarity. I have shown in my thesis, using STED microscopy, that Vangl2 asymmetry is mainly due to an accumulation of Vangl2 to the distal side of supporting cells. I sought to dissect the molecular role of Vangl2 by analysing its trafficking within the cochlear epithelium. Deletion analysis shows that the last 12 amino acids, unlike its N-terminus tail are essential for Vangl2 endoplasmic reticulum sorting, its plasma membrane targeting and its function. Conditional mutant mice analysis show that Scrib1, which we have previously shown, interacts with Vangl2 through the PDZ binding domain of its C-terminal tail, is not the protein mediating this asymmetry. My work also highlight that GIPC1 had a role in the regulation of PCP and maintaining the integrity of hair bundles of sensory cells, and that the complex GIPC1/Myosin VI could regulate Vangl2 asymmetry in the organ of Corti
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Mohammad, Hani Ali Yasin. "Iridium-PCP pincer complexes C-H oxidative addition reactions and functionalisation = Iridium-PCP-Pincer-Komplexe /." [S.l. : s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=965171310.

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Books on the topic "Pcpe"

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Fund, International Monetary. From centrally-planned to market economies: The road from CPE to PCPE. [Washington]: International Monetary Fund, Research Department, 1991.

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Calvo, Guillermo A. From centrally-planned to market economies: The road from CPE to PCPE. Cambridge, MA: National Bureau of Economic Research, 1991.

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Newman, Gerald. PCP. Springfield, NJ: Enslow Publishers, 1997.

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PCP. San Diego, Calif: Lucent Books, 2005.

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Poppa, Anna. PCP: An overview. 2nd ed. London: Body Positive, 1995.

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Wakeman, Lois. PCTE: The standard for open repositories. New York: Prentice Hall, 1993.

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Moreira, Vital. Reflexões sobre o PCP. 2nd ed. Lisboa: Editorial Inquérito, 1990.

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Tobella, Joan Estruch. Historia oculta del PCE. Madrid: Temas de Hoy, 2000.

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Poolos, Christine. The truth about PCP. New York: Rosen Publishing, 2014.

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Carroll, Marilyn. PCP, the dangerous angel. New York: Chelsea House Publishers, 1992.

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Book chapters on the topic "Pcpe"

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Kessler, Efrat, and Eyal Hassoun. "Procollagen C-Proteinase Enhancer 1 (PCPE-1) in Liver Fibrosis." In Methods in Molecular Biology, 189–201. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9095-5_14.

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Leasure, Bruce, David J. Kuck, Sergei Gorlatch, Murray Cole, Gregory R. Watson, Alain Darte, David Padua, et al. "PCIe." In Encyclopedia of Parallel Computing, 1498. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-0-387-09766-4_2355.

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McAllister-Williams, R. Hamish, Daniel Bertrand, Hans Rollema, Raymond S. Hurst, Linda P. Spear, Tim C. Kirkham, Thomas Steckler, et al. "PCP." In Encyclopedia of Psychopharmacology, 976. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-68706-1_4450.

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Braun-Falco, Markus, Henry J. Mankin, Sharon L. Wenger, Markus Braun-Falco, Stephan DiSean Kendall, Gerard C. Blobe, Christoph K. Weber, et al. "PcP." In Encyclopedia of Molecular Mechanisms of Disease, 1592–93. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_7694.

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Braun-Falco, Markus, Henry J. Mankin, Sharon L. Wenger, Markus Braun-Falco, Stephan DiSean Kendall, Gerard C. Blobe, Christoph K. Weber, et al. "PCP." In Encyclopedia of Molecular Mechanisms of Disease, 1593. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-29676-8_7695.

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Schuckit, Marc A. "Phencyclidine (PCP)." In Drug and Alcohol Abuse, 206–16. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4757-2407-3_9.

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Schuckit, Marc A. "Phencyclidine (PCP)." In Drug and Alcohol Abuse, 210–20. Boston, MA: Springer US, 2000. http://dx.doi.org/10.1007/978-1-4757-3232-0_9.

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Schuckit, Marc A. "Phencyclidine (PCP)." In Drug and Alcohol Abuse, 174–83. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4757-0767-0_9.

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Dinur, Irit, and Prahladh Harsha. "Composition of Low-Error 2-Query PCPs Using Decodable PCPs." In Property Testing, 280–88. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-16367-8_21.

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Kiyoshima, Susumu. "No-signaling Linear PCPs." In Theory of Cryptography, 67–97. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-030-03807-6_3.

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Conference papers on the topic "Pcpe"

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Tipler, Steven, Alessandro Parente, Axel Coussement, Francesco Contino, Steffen H. Symoens, Marko R. Djokic, and Kevin M. Van Geem. "Prediction of the PIONA and oxygenate composition of unconventional fuels with the Pseudo-Component Property Estimation (PCPE) method. Application to an Automotive Shredder Residues-derived gasoline." In WCX World Congress Experience. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 2018. http://dx.doi.org/10.4271/2018-01-0905.

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Belakhovsky, Vladimir, Yaqi Jin, and Wojciech Miloch. "Impact of the substorms and polar cap patches on GPS radio waves at polar latitudes." In Physics of Auroral Phenomena. FRC KSC RAS, 2020. http://dx.doi.org/10.37614/2588-0039.2020.43.020.

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The comparative research of the influence of substrorm precipitation and polar cap patches (PCP) on the GPS signals disturbances in the polar ionosphere was done. For this aim we use the GPS scintillation receivers at Ny-Ålesund, operated by the University of Oslo. The presence of the auroral particle precipitation and polar cap patches was determined by using data from the EISCAT 42m radar on Svalbard. We consider tens of events when the simultaneous EISCAT 42m and GPS data were available. We demonstrate that substorm-associated precipitations can lead to a strong GPS phase (σΦ) scintillations up to ~2 radians which is much stronger than those usually produced by PCPs. At the same PCPs can lead to strong ROT (rate of total electron content) variations. So our observations suggest that the substorms and PCPs, being different types of the high-latitude disturbances, lead to the development of different types and scales of ionospheric irregularities.
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Yucel, Ozhan, Brenda Levy, Gustavo Andres Ariza Gonzalez, Wayne Pilgrim, and Tim Wayne Soltys. "Progressing Cavity Pump Stainless Steel Impact in High Corrosive Environments Maximizing Economic Benefits in West Africa - Gabon." In SPE Annual Technical Conference and Exhibition. SPE, 2021. http://dx.doi.org/10.2118/205869-ms.

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Abstract The combination of well conditions such as high levels of carbon dioxide (CO2, an average of 15%), 85% water cuts (WC), sand production, and heavy viscous oil is one of the biggest challenges for any artificial lift system (ALS). Progressing cavity pumping (PCP) is the preferred method for sand and heavy oil production; however, CO2 presence in the form of carbonic acid, generates corrosion and pitting on the carbon-steel section of the Progressing Cavity stators. This condition results in short run life for PC pumps with standard materials historically installed. Taking advantage of the corrosion strength properties that Stainless Steel (SS) material has, a new SS PC pumps were manufactured to be installed in highly corrosive application and then determine the increase on run life for those wells previously affected by corrosion. This paper describes a section of the results from the flow assurance improvement plan obtained by the installation of PC pumps with SS technology in terms of workover (WO) intervention savings and extended run life in nine wells operating in Gabon, West Africa. This paper describes the methodology applied in the selection of the PCP models to be manufactured with Stainless Steel technology considering the dimensional restrictions the PCP would have due the casing size of the well completions where the PC pump would be installed, as well as the pump design requirements related to the expected flow rate in the wells historically affected by corrosion. In addition, the paper shows the screening done on the well candidates for the installation of SS PCP, based on historical well intervention data specifically associated to corrosion. Since the installation of the SS PCP technology, the client has performed several acid stimulations that have required pulling the PC pumps out of hole and re-running them multiple times. Throughout these operations, the PCPs have had no failures requiring intervention. The installation of SS technology has improved well run life across all nine candidates by 584% on average. The SS PCP technology continue to run in all nine wells with no corrosion-associated interventions. For an average of 326 days across all nine wells, there have been no WOs performed on the PCPs. The reduction in WOs has helped to avoid production losses, downtime, and associated costs. SS PCP has shown great results extending PC pump run life over 6 times compared to previous applications and has proven to be a good option for larger flow rates in 5.5 in casing completions.
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Boudier, Gerard, Ferdinando Gallo, Regis Minot, and Ian Thomas. "An overview of PCTE and PCTE+." In the third ACM SIGSOFT/SIGPLAN software engineering symposium. New York, New York, USA: ACM Press, 1988. http://dx.doi.org/10.1145/64135.65026.

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Verdiell, Jean-Marc, Eric Zbinden, Raymond Lee, and Benjamin Troxell. "PCIe optical interconnects." In 2011 IEEE Avionics, Fiber- Optics and Photonics Technology Conference (AVFOP). IEEE, 2011. http://dx.doi.org/10.1109/avfop.2011.6082107.

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Ergün, Funda, Ravi Kumar, and Ronitt Rubinfeld. "Fast approximate PCPs." In the thirty-first annual ACM symposium. New York, New York, USA: ACM Press, 1999. http://dx.doi.org/10.1145/301250.301267.

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Balakrishnan, Hari, Nikolaus Correll, Jakob Erikkson, Sejoon Lim, Samuel Madden, and Daniela Rus. "PCP." In the 6th ACM conference. New York, New York, USA: ACM Press, 2008. http://dx.doi.org/10.1145/1460412.1460448.

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Kapitsaki, Georgia M., and Iakovos S. Venieris. "PCP." In the 10th International Conference. New York, New York, USA: ACM Press, 2008. http://dx.doi.org/10.1145/1497308.1497332.

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Ben-Sasson, Eli, Oded Goldreich, Prahladh Harsha, Madhu Sudan, and Salil Vadhan. "Robust pcps of proximity, shorter pcps and applications to coding." In the thirty-sixth annual ACM symposium. New York, New York, USA: ACM Press, 2004. http://dx.doi.org/10.1145/1007352.1007361.

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Dinur, Irit, and Prahladh Harsha. "Composition of Low-Error 2-Query PCPs Using Decodable PCPs." In 2009 IEEE 50th Annual Symposium on Foundations of Computer Science (FOCS). IEEE, 2009. http://dx.doi.org/10.1109/focs.2009.8.

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Reports on the topic "Pcpe"

1

Calvo, Guillermo, and Jacob Frenkel. From Centrally-Planned to Market Economies: The Road from CPE to PCPE. Cambridge, MA: National Bureau of Economic Research, May 1991. http://dx.doi.org/10.3386/w3698.

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Wu, Q., and D. Ceccarelli. PCE Communication Protocol (PCEP) Extensions for Label Switched Path (LSP) Scheduling with Stateful PCE. Edited by H. Chen and Y. Zhuang. RFC Editor, October 2020. http://dx.doi.org/10.17487/rfc8934.

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Sivabalan, S., J. Tantsura, I. Minei, R. Varga, and J. Hardwick. Conveying Path Setup Type in PCE Communication Protocol (PCEP) Messages. RFC Editor, July 2018. http://dx.doi.org/10.17487/rfc8408.

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Crabbe, E., I. Minei, J. Medved, and R. Varga. Path Computation Element Communication Protocol (PCEP) Extensions for Stateful PCE. RFC Editor, September 2017. http://dx.doi.org/10.17487/rfc8231.

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Crabbe, E., I. Minei, S. Sivabalan, and R. Varga. Path Computation Element Communication Protocol (PCEP) Extensions for PCE-Initiated LSP Setup in a Stateful PCE Model. RFC Editor, December 2017. http://dx.doi.org/10.17487/rfc8281.

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Li, Z., and C. Zhou. An Architecture for Use of PCE and the PCE Communication Protocol (PCEP) in a Network with Central Control. Edited by A. Farrel and Q. Zhao. RFC Editor, December 2017. http://dx.doi.org/10.17487/rfc8283.

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Zhang, F., Q. Zhao, O. Gonzalez de Dios, R. Casellas, and D. King. Path Computation Element Communication Protocol (PCEP) Extensions for the Hierarchical Path Computation Element (H-PCE) Architecture. RFC Editor, December 2019. http://dx.doi.org/10.17487/rfc8685.

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Ananthakrishnan, H., S. Sivabalan, C. Barth, I. Minei, and M. Negi. Path Computation Element Communication Protocol (PCEP) Extensions for Associating Working and Protection Label Switched Paths (LSPs) with Stateful PCE. RFC Editor, March 2020. http://dx.doi.org/10.17487/rfc8745.

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Palle, U., R. Singh, and L. Fang. Path Computation Element Communication Protocol (PCEP) Extensions for MPLS-TE Label Switched Path (LSP) Auto-Bandwidth Adjustment with Stateful PCE. Edited by D. Dhody and R. Gandhi. RFC Editor, February 2020. http://dx.doi.org/10.17487/rfc8733.

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Li, Z., S. Peng, M. Negi, Q. Zhao, and C. Zhou. Path Computation Element Communication Protocol (PCEP) Procedures and Extensions for Using the PCE as a Central Controller (PCECC) of LSPs. RFC Editor, July 2021. http://dx.doi.org/10.17487/rfc9050.

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