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Journal articles on the topic 'Peas – Cytology'

Author: Grafiati

Published: 4 June 2021

Last updated: 14 February 2022

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1

Mehta, Mansi, Nisha Gupta, Jaydeep Odhwani, Nandini Desai, and P. M. Santwani. "Lung cancer: 1 year experience at tertiary care centre with reference to cytodiagnostic approach." International Journal of Advances in Medicine 4, no. 1 (2017): 133. http://dx.doi.org/10.18203/2349-3933.ijam20170096.

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Background: Lung cancer is the most common cancer incidence wise as well as leading cause of cancer related death in worldwide as well as in India. Cytological diagnosis plays an important role in patients having lung cancer. This study was conducted to evaluate sensitivity of various cytological methods in diagnosis of lung cancer, to study typing of lung cancer, age and gender wise distribution of lung cancer and its association with smoking.Methods: This study includes patients having clinical and radiological diagnosis of lung cancer. Total 150 cases of entire January 2015 to December 2015

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Chesney, Kari L., Caroline Chang, and Elizabeth C. Bryda. "Using Vaginal Impedance Measurement to Identify Proestrus in Rats Given Luteinizing Hormone Releasing Hormone (LHRH) Agonist." Journal of the American Association for Laboratory Animal Science 59, no. 3 (2020): 282–87. http://dx.doi.org/10.30802/aalas-jaalas-19-000112.

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Vaginal cytology is the most common method of monitoring the estrous cycle in rats; however, this test requires specific technical training and can be subject to interpretation. Vaginal impedance offers a quicker and less technically challenging alternative and has been used successfully to identify estrus in normally cycling breeder rats. We hypothesize that vaginal impedance can also be used to stage the estrous cycle in rats that have been given luteinizing hormone releasing hormone (LHRH) for timed mating. Vaginal impedance measurements and vaginal cytology were performed in LHRH-primed fe

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Chen, D. h., G. y. Zhong, W. Luo, et al. "Reference Values of Induced Sputum Cytology in Healthy Children in Guangzhou, Southern China." PEDIATRICS 131, no. 2 (2013): e518-e524. http://dx.doi.org/10.1542/peds.2012-0946.

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Sahu, Alaka, Santosh Gudaganatti, and Swetalina Pandey. "Cytopathologic Evaluation of Image-Guided Fine-Needle Aspiration Cytology and Cell Block Correlation for Lung Neoplasm in a Tertiary Care Hospital VIMSAR, Burla - A Cross-Sectional Study." Journal of Evidence Based Medicine and Healthcare 8, no. 23 (2021): 1927–31. http://dx.doi.org/10.18410/jebmh/2021/362.

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BACKGROUND Fine-needle aspiration cytology (FNAC) is an easy, minimally invasive and useful investigation, and is considered important next to imaging in the rapid diagnosis of lung neoplasm for the last few decades. The purpose of this study was to evaluate the role of image-guided FNAC in pulmonary neoplasm, analyse the results and correlate with cell block histopathological findings. METHODS This is a cross sectional study conducted over a period of two years, involving fifty patients. All the clinical and radiological data were studied from the consenting patient. Then they underwent image

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Ottaviano, Giancarlo, Ennio Nardello, Alfonso Luca Pendolino, et al. "Nasal Function Changes at High Altitude." American Journal of Rhinology & Allergy 34, no. 5 (2020): 618–25. http://dx.doi.org/10.1177/1945892420916393.

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Background An ever-increasing number of people are involved in sport activities at high altitude. Objective This study aimed to evaluate the pulmonary and nasal functions, including nasal cytology, in healthy volunteers moving for 1 week from an altitude of 2000 m to another of 3400 m. Methods Peak nasal inspiratory flow (PNIF), pulmonary function, including peak expiratory flow (PEF), mucociliary transport time (MCTt), nasal cytology, and oxygen saturation (O2 sat) were studied in 5 different occasions—T1: at base camp (2000 m); T2: at the mountain refuge (3400 m); T3: after 7 days at 3400 m;

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Malladi, Anish, Peter Goldsbrough, and Peter Hirst. "Regulation of Fruit Growth and Fruit Size in Apple." HortScience 40, no. 4 (2005): 1097A—1097. http://dx.doi.org/10.21273/hortsci.40.4.1097a.

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Fruit development in apple cultivars varying in their ultimate fruit size was analyzed using cytology, flow cytometry (FCM), and semi-quantitative RT-PCR. Fruit size variation across cultivars was largely explained by variation in cell number. The cell division phase lasted for less than 30 days in all varieties, less than previously believed. A distinct overlap between the cell division and cell expansion phases was present. Analysis of the relative cell production rate (rCPR) showed a major peak about 10 days after full bloom (DAFB) after which it declined. Comparison of the rCPR across vari

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Arseniev, A., A. Nefedova, A. Ganeeva, et al. "COMBINED DIAGNOSTICS OF LUNG CANCER USING EXHALED BREATH ANALSYSIS AND SPUTUM CYTOLOGY." Problems in oncology 66, no. 4 (2020): 381–84. http://dx.doi.org/10.37469/0507-3758-2020-66-4-381-384.

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In this article we summarize our own experience of lung cancer diagnostics using exhaled breath analysis with a non-selective method using metal oxide chemoresistor gas sensors with cross-sensitivity combined with the sputum cytology. Volatile organic compounds of exhaled breath change the conductivity of the sensor, the resulting pulse is displayed as a peak on the graph, the area of which is used as test results. The combination of two diagnostic techniques in 204 participants demonstrated the possibility of non-invasively detecting the disease at an early stage. The sensitivity, specificity

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Sinard, John H. "An Analysis of the Effect of the COVID-19 Pandemic on Case Volumes in an Academic Subspecialty-Based Anatomic Pathology Practice." Academic Pathology 7 (January 1, 2020): 237428952095978. http://dx.doi.org/10.1177/2374289520959788.

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The recent COVID pandemic has had a major effect on anatomic pathology specimen volumes across the country. The effect of this pandemic on a subspecialty academic practice is presented. We used a data-driven approach to monitor the changing workloads in a granular fashion and dynamically adjust the scheduling of faculty and histology staff accordingly to minimize the number of people present on-site. At the peak of the pandemic locally, the main hospital in our health system had 450 COVID-positive inpatients. The surgical pathology specimen volume dropped to 13% of the pre-pandemic levels, and

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Maia, Keilla M., Gislayne C. X. Peixoto, Lívia B. Campos, et al. "Estrus cycle monitoring of captive collared peccaries (Pecari tajacu) in semiarid conditions." Pesquisa Veterinária Brasileira 34, no. 11 (2014): 1115–20. http://dx.doi.org/10.1590/s0100-736x2014001100014.

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Collared peccaries (Peccary tajacu) are among the most hunted species in Latin America due the appreciation of their pelt and meat. In order to optimize breeding management of captive born collared peccaries in semiarid conditions, the objective was to describe and correlate the changes in the ovarian ultrasonographic pattern, hormonal profile, vulvar appearance, and vaginal cytology during the estrus cycle in this species. During 45 days, females (n=4) were subjected each three days to blood collection destined to hormonal dosage by enzyme immunoassay (EIA). In the same occasions, evaluation

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Van Biervliet, Stephanie, Jean Pierre Van Biervliet, Karel Watteyne, Michel Langlois, Dirk Bernard, and Johan Vande Walle. "Pseudonephritis is Associated With High Urinary Osmolality and High Specific Gravity in Adolescent Soccer Players." Pediatric Exercise Science 25, no. 3 (2013): 360–69. http://dx.doi.org/10.1123/pes.25.3.360.

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The study aimed to evaluate the effect of exercise on urine sediment in adolescent soccer players. In 25 15-year-old (range 14.4–15.8 yrs) athletes, urinary protein, osmolality and cytology were analyzed by flow cytometry and automated dipstick analysis before (T0), during (T1), and after a match (T2). All athletes had normal urine analysis and blood pressure at rest, tested before the start of the soccer season. Fifty-eight samples were collected (T0: 20, T1: 17, T2: 21). Proteinuria was present in 20 of 38 samples collected after exercise. Proteinuria was associated with increased urinary os

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Alqallaf, Abdullah, Mariana Ahmad Zuber, Shehnoor Tarique, and Alina A. Ionescu. "Awake sedation thoracoscopy for the diagnosis of malignant mesothelioma: a service review." Pneumologia 68, no. 1 (2019): 27–30. http://dx.doi.org/10.2478/pneum-2019-0012.

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Abstract Background Mortality from malignant mesothelioma is expected to peak in the UK in the current decade. Areas of the country which have historically high rates of industrial exposure to asbestos, such as South East Wales, are expected to bear a disproportionately high burden of mesothelioma, making a priority. Medical thoracoscopy is an effective and safe procedure, affording both a high diagnostic yield in mesothelioma and an opportunity to carry out therapeutic drainage of pleural effusion. Methods We evaluated the diagnostic yield and safety of medical thoracoscopy at our centre over

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Pendolino, Alfonso Luca, Bruno Scarpa, and Giancarlo Ottaviano. "Relationship Between Nasal Cycle, Nasal Symptoms and Nasal Cytology." American Journal of Rhinology & Allergy 33, no. 6 (2019): 644–49. http://dx.doi.org/10.1177/1945892419858582.

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Background The nasal cycle is the spontaneous congestion and decongestion of nasal mucosa that happens during the day. Classically, 4 types of nasal cycle patterns have been described: (1) classic, (2) parallel, (3) irregular, and (4) acyclic. Hypothalamus has been considered as the central regulator even if several external factors may influence its activity. Objective The aim of the study was to evaluate the presence of a correlation between nasal cycle pattern, nasal cytology and nasal symptoms. Methods Thirty healthy volunteers have been enrolled in the study. All subjects completed a Sino

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Wang, Lin-Jiao, and Mao-Yin Sheng. "The Cytology, Isozyme, HPLC Fingerprint, and Interspecific Hybridization Studies of Genus Epimedium (Berberidaceae)." ISRN Pharmacology 2013 (November 19, 2013): 1–11. http://dx.doi.org/10.1155/2013/271578.

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104 samples from 27 accessions belonging to 12 species of genus Epimedium were studied on the basis of cytology observation, POD (i.e., peroxide) isozyme, high performance liquid chromatography (i.e., HPLC) fingerprint, and interspecific hybridization. The cytology observation showed karyotypes of twelve species studied; all are 2A symmetry type of Stebbins standard and similar to each other, and except for karyotype of E. leptorrhizum which is 2n = 2x = 8m (2SAT) + 4sm, the rest are 2n = 2x = 6m (2SAT) + 6sm. Chromosomes C-banding of barrenwort species varies, with 15 to 22 bands, consisting

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Perna, Giuseppe, Vito Capozzi, and Maria Lasalvia. "A Comparison between FTIR Spectra from HUKE and SH-SY5Y Cell Lines Grown on Different Substrates." Applied Sciences 10, no. 24 (2020): 8825. http://dx.doi.org/10.3390/app10248825.

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In recent years, Fourier Transform Infrared (FTIR) micro-spectroscopy has shown promising potential in medical diagnostics at the cellular level. In fact, FTIR spectra can provide information related to DNA, protein, and lipid content and how such a content changes when a pathological state arises. Most of these information is included in the so-called fingerprint region (1000–1800 cm−1), consisting of several spectral peaks related to vibrational modes occurring inside cellular components. Unfortunately, the slides commonly used in cytology (as the glass microscopy slides and coverslips) are

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Mondal, Santosh Kumar, Dipanwita Nag, Biren Parikh, Manoj Shah, and Kajal Davara. "Computed tomogram guided fine-needle aspiration cytology of lung mass with histological correlation: A study in Eastern India." South Asian Journal of Cancer 02, no. 01 (2013): 014–18. http://dx.doi.org/10.4103/2278-330x.105881.

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Abstract Background: Fine-needle aspiration cytology (FNAC) is an important and useful investigation, and is considered next to imaging in the rapid diagnosis of pulmonary mass lesion for the last few decades. Aims: To assess the role of Computed Tomogram (CT) guided FNAC in pulmonary mass lesions; to analyze the results; and to compare with histopathological findings. Materials and Methods: The clinical, radiological, and cytological data of 130 patients were prospectively studied who underwent CT guided FNAC from October 2009 through September 2011. Thereafter these patients underwent bronch

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Carney, A. S., J. F. Sharp, and N. J. A. Cozens. "Atypically located submandibular gland diagnosed by Doppler ultrasound." Journal of Laryngology & Otology 110, no. 12 (1996): 1171–72. http://dx.doi.org/10.1017/s0022215100136060.

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AbstractThe anatomical location and relationships of the submandibular gland are well-known to most otolaryngologists and gross variations from the norm are rare. We report a case of an atypical submandibular gland located 2 cm below the mandible which presented as a painful neck swelling with non-diagnostic fine needle aspiration cytology. Using Doppler ultrasound the mass was noted to be closely located to the facial artery and vein and following the administration of oral lemon juice, the peak systolic velocity of a small artery within the mass rose from 8.5 cm/s to 16.4 cm/s, confirming th

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Ballantyne, K., P. Matson, N. Noakes, V. Nicolson, and S. D. Johnston. "Reproductive physiology of the female greater bilby (Macrotis lagotis Thylacomyidae): evidence for a male-induced luteal phase." Reproduction, Fertility and Development 21, no. 2 (2009): 274. http://dx.doi.org/10.1071/rd08134.

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Endocrinology of the oestrous cycle, pregnancy and early lactation was investigated in captive Western Australian greater bilbies (Macrotis lagotis). Initially, six females were monitored for changes in urogenital cytology, plasma progestogen, pericloacal and pouch morphology in the absence of a male. This was followed by the introduction of a male and a reproductive assessment through mating, gestation and early lactation. In the absence of a male, there was no cyclical pattern of urogenital cytology, pericloacal or pouch development, and progestogen concentrations remained basal. Within 5 da

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Pijanka, Jacek K., Nicholas Stone, Gianfelice Cinque, et al. "FTIR microspectroscopy of stained cells and tissues. Application in cancer diagnosis." Spectroscopy 24, no. 1-2 (2010): 73–78. http://dx.doi.org/10.1155/2010/587947.

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It is widely accepted that FTIR spectroscopy has a huge potential in cancer diagnosis. However further work is required to bring this technique into pathology departments. One of the areas where big efforts will be required is the development of cell spectra databases to be used in the diagnosis of cancer. Presently, unstained cytology and tissue samples are studied with FTIR spectroscopy. However, it is not always possible to identify in unstained samples the types of cells present. In order to achieve this, samples need staining after FTIR spectra have been obtained. We have recently shown i

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Mandal, Manit M., Ajay J. Panchal, Rakesh Kumar, Parth B. Kapadia, and Vipul Valiya. "Fine-needle aspiration cytology (pre-operative) and histopathological (post-operative) correlation in thyroid swellings." International Journal of Otorhinolaryngology and Head and Neck Surgery 7, no. 6 (2021): 1035. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20212129.

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<p class="abstract"><strong>Background:</strong> Fine-needle aspiration cytology (FNAC) is one of the most important pre-operative procedures used in the primary diagnosis of thyroid swelling. Even if non-surgical and non-invasive techniques can provide a diagnosis, the ultimate answer rests in the histopathological examination of the surgically excised thyroid tissue. A correlation of both FNAC and HPE though can help predict outcomes and may be helpful to avoid unnecessary surgical procedures for benign conditions. The purpose of this study was to establish a cyto-histologi

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Yang, Ling, Wen-Tao Liu, Hao Wu, Cheng Wang, Bo Ping, and Da-Ren Shi. "Separation of Normal and Premalignant Cervical Epithelial Cells Using Confocal Light Absorption and Scattering Spectroscopic MicroscopyEx Vivo." Journal of Biomedicine and Biotechnology 2011 (2011): 1–5. http://dx.doi.org/10.1155/2011/214781.

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Confocal light absorption and scattering spectroscopic (CLASS) microscopy can detect changes in biochemicals and the morphology of cells. It is therefore used to detect high-grade cervical squamous intraepithelial lesion (HSIL) cells in the diagnosis of premalignant cervical lesions. Forty cervical samples from women with abnormal Pap smear test results were collected, and twenty cases were diagnosed as HSIL; the rest were normal or low-grade cervical squamous intraepithelial lesion (LSIL). The enlarged and condensed nuclei of HSIL cells as viewed under CLASS microscopy were much brighter and

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Murugan, Paari, Debdatta Basu, Surendra Kumar, and Sadasivan Jagadish. "Clear cell sarcoma of the soft parts arising in the rectus abdominis in a child – aspiration cytology of a rare case." CytoJournal 4 (July 15, 2007): 15. http://dx.doi.org/10.1186/1742-6413-4-15.

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Background Clear cell sarcoma of soft parts is most commonly found associated with the tendons and aponeuroses of distal extremities in young adults with a peak incidence in the third decade. Location in the abdominal wall and in a child is very rare. Case presentation A nine-year-old female child presented with a swelling in the anterior abdominal wall in the suprapubic region. Fine needle aspiration revealed predominantly discrete cells with loose clustering at places. The cytoplasm was abundant, finely granular, and eosinophilic with some cells exhibiting clear vacuolated zones. No pigment

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Sarkar, Saurav, Arista Lahiri, Soumyajyoti Bandyopadhyay, Snehasish Das, and Tamal Chakraborty. "Benign and malignant lesions of the breast: clinico-pathological perspective from a government teaching hospital in West Bengal, India." International Surgery Journal 5, no. 11 (2018): 3460. http://dx.doi.org/10.18203/2349-2902.isj20184609.

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Background: While breast cancer is one of the most commonly diagnosed cancer more than half of the women develop some benign disease of breast in their lifetime. The current study was conducted to describe the clinico-pathological findings associated with breast diseases and study their relationship.Methods: A record-based cross-sectional study was conducted on the samples of breast tissue obtained by fine needle aspiration cytology (FNAC) examination. The clinical variables like age, sex, presenting complaint, involved side (right/left/both) etc. were taken from the clinical notes sent, and n

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Singh, Dalpat, Mohan Makwana, G. L. Verma, and Kanwar Lal. "Evaluation of thyroid nodules by Gray scale and Doppler sonography and correlation with fine needle aspiration cytology." International Surgery Journal 4, no. 7 (2017): 2197. http://dx.doi.org/10.18203/2349-2902.isj20172766.

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Background: Nodular goiter is a worldwide disease and is encountered commonly in clinical practice by primary care physicians, endocrinologist, surgeons and otolaryngologists. The solitary thyroid nodule is common presentation & the incidence of carcinoma in single thyroid nodule is between 8-20% and in multinodular goiter is about 5%. Ultrasonography (USG), both Gray scale and color Doppler is useful in diagnosis of various thyroid lesions and can be utilized to correlate USG features with histopathological findings wherever possible.Methods: The present study was conducted in the Departm

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Crivellaro, Maria Angiola, Giancarlo Ottaviano, Pietro Maculan, et al. "Upper and Lower Respiratory Signs and Symptoms in Workers Occupationally Exposed to Flour Dust." International Journal of Environmental Research and Public Health 17, no. 19 (2020): 7075. http://dx.doi.org/10.3390/ijerph17197075.

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A group of 142 bakers was studied in order to investigate the relationship between higher/lower respiratory signs/symptoms and inflammation biomarkers and occupational exposure to flour dust. A complete upper and lower respiratory tract evaluation was performed. Seven percent of bakers complained of lower respiratory symptoms, while 22% of them complained of upper respiratory symptoms. Fifty five percent of the bakers were allergic, and 37.1% showed sensitization to occupational allergens. Abnormal spirometries were found in 15% of bakers, while fractional exhaled nitric oxide (FeNO) was above

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Krishna, Nallamothu Murali, Vietla Sreeramulu, Sai Krishna Gurrala, and T. Jaya Chandra. "Aetiopathological evaluation of pleural effusions." International Journal of Advances in Medicine 7, no. 1 (2019): 90. http://dx.doi.org/10.18203/2349-3933.ijam20195651.

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Background: Pleural Effusion (PE) is a sign of disease and not a diagnosis itself. Hence an attempt was made to find out the etiological diagnosis of pleural effusion in cases.Methods: Single center, observational, cross sectional hospital-based study. Samples were collected by systematic random sampling method; study was conducted in GSL Medical College. Patients admitted with pleural effusion in medical wards and ICU were taken. The patients >14 years age, both genders were included. All patients were interviewed to obtain detailed history and examined thoroughly as per pre-determined pro

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Kaludov, Nikola, Mohummad Minhaj Siddiqui, Max Kates, et al. "Validation of an artificial intelligence algorithm applied to a metabolic substrate analysis of urine for detection of urothelial cancer." Journal of Clinical Oncology 37, no. 15_suppl (2019): e16008-e16008. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e16008.

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e16008 Background: Urine tests such as urine cytology are commonly used for the diagnosis and monitoring of urothelial cancer. These tests are often limited by issues related to sensitivity or specificity. It is well known that derangement of cellular metabolism is one of the hallmarks of carcinogenesis. As urothelial cancer is in constant contact with urine, we hypothesize that metabolite composition in the urine may provide insight into possible urothelial cancer presence in the urinary tract. In this study, we evaluated a metabolomics based urine test for the detection of urothelial cancer.

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Sadé, Jacob, Camil Fuchs, Eyal Russo, and David Cohen. "Is Secretory Otitis Media a Single Disease Entity?" Annals of Otology, Rhinology & Laryngology 112, no. 4 (2003): 342–47. http://dx.doi.org/10.1177/000348940311200408.

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The outcome of 809 children who had middle ear effusion (MEE) was correlated with their age and medical history and the bacteriologic and cytologic findings of the MEE. Three groups emerged. Group A (n = 384) had a medical history of relatively recent acute otitis media (AOM) with a peak prevalence of 2.6 years of age, and its MEE was hypercellular (mostly polymorphonuclear leukocytes) with a 24% rate of positive bacteriologic culture. In contrast, the peak prevalence of group B (n = 280) was approximately 5 years of age. Its MEE followed no otologic medical history and was bacteriologically s

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Agodi, Antonella, Martina Barchitta, Nadia La Rosa, et al. "Human Papillomavirus Infection: Low-Risk and High-Risk Genotypes in Women in Catania, Sicily." International Journal of Gynecologic Cancer 19, no. 6 (2009): 1094–98. http://dx.doi.org/10.1111/igc.0b013e3181a83c9d.

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Introduction:Human papillomavirus (HPV) infection has been strongly and consistently associated with cervical carcinoma and its cytologic precursors, such as squamous intraepithelial lesions. A cross-sectional survey was conducted with the aim of estimating the prevalence of cervical HPV infection in women attending a service of colposcopy in Catania, Eastern Sicily, Italy.Methods:The prevalence of type-specific HPV was examined in women with negative colposcopic results and cervical intraepithelial neoplasia grades 1, 2, or 3, with the aim of providing some cross-sectional figures on the loca

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Asokan, Dr Vinodhini, Dr Koshalya Rajendran, and Dr Muthu Sudalaimuthu. "Unique Features of Hashimoto’s Thyroiditis in Coastal South India – a study from a tertiary care hospital." Tropical Journal of Pathology and Microbiology 6, no. 8 (2020): 466–71. http://dx.doi.org/10.17511/jopm.2020.i08.02.

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Background: Hashimoto’s thyroiditis is an autoimmune disorder of thyroid gland. It is one of thecommon causes of hypothyroidism and is common in females. Generally, Hashimoto’s thyroiditisclinically presents as diffuse enlargement of the thyroid and nodular lesions are uncommon. But fewrecent studies from South India have shown that Hashimoto’s frequently presents as nodularenlargement of the thyroid. Such lesions can be easily confused with nodular goitre. Objectivesand Aim: Aim of the study is to study the clinicopathological features of Hashimoto’s thyroiditis andto estimate the frequency o

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Asokan, Dr Vinodhini, Dr Koshalya Rajendran, and Dr Muthu Sudalaimuthu. "Unique Features of Hashimoto’s Thyroiditis in Coastal South India – a study from a tertiary care hospital." Tropical Journal of Pathology and Microbiology 6, no. 8 (2020): 466–71. http://dx.doi.org/10.17511/jopm.2020.i08.02.

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Background: Hashimoto’s thyroiditis is an autoimmune disorder of thyroid gland. It is one of thecommon causes of hypothyroidism and is common in females. Generally, Hashimoto’s thyroiditisclinically presents as diffuse enlargement of the thyroid and nodular lesions are uncommon. But fewrecent studies from South India have shown that Hashimoto’s frequently presents as nodularenlargement of the thyroid. Such lesions can be easily confused with nodular goitre. Objectivesand Aim: Aim of the study is to study the clinicopathological features of Hashimoto’s thyroiditis andto estimate the frequency o

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Zhou, Juntong, Xiao Wu, Yuezhu Ma, Zhenpeng Wang, and Qing Huo. "Uptake and Transport Mechanisms of Ginkgolide B Niosomal Composite Drug Through the Blood-Brain Barrier." Nanoscience and Nanotechnology Letters 12, no. 12 (2020): 1345–54. http://dx.doi.org/10.1166/nnl.2020.3257.

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Cerebrovascular and functional neurological lesions are the major disorders threatening human health and quality of life. The presence of the blood-brain barrier seriously affects the distribution and efficacy of various drugs in the brain. Ginkgolide B (GB) and Puerarin (Pue) are active pharmaceutical ingredients for the treatment of Parkinson’s disease. Here, we have developed a novel strategy to construct a GB-Pue niosomal composite drug. The in vitro cytology study of the niosomal composite drug showed that 20 mmol/L glutamate resulted in a mortality of 50–60% in the SHSY-5Y cells, while 3

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Glantz, M. J., B. F. Cole, L. Recht, et al. "High-dose intravenous methotrexate for patients with nonleukemic leptomeningeal cancer: is intrathecal chemotherapy necessary?" Journal of Clinical Oncology 16, no. 4 (1998): 1561–67. http://dx.doi.org/10.1200/jco.1998.16.4.1561.

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PURPOSE Standard treatments for neoplastic meningitis are only modestly effective and are associated with significant morbidity. Isolated reports suggest that concurrent systemic and intrathecal (i.t.) therapy may be more effective than i.t. therapy alone. We present our experience, which includes CSF and serum pharmacokinetic data, on the use of high-dose (HD) intravenous (i.v.) methotrexate (MTX) as the sole treatment for neoplastic meningitis. PATIENTS AND METHODS Sixteen patients with solid-tumor neoplastic meningitis received one to four courses (mean, 2.3 courses) of HD (8 g/m2 over 4 ho

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Brandler, Tamar C., Dana Warfield, Esther Adler, et al. "Lessons Learned From an Anatomic Pathology Department in a Large Academic Medical Center at the Epicenter of COVID-19." Academic Pathology 8 (January 1, 2021): 237428952199424. http://dx.doi.org/10.1177/2374289521994248.

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Many state-wide, city-wide, and hospital-wide changes have been implemented due to the ongoing COVID-19 crisis. We describe lessons learned in an anatomic pathology division at a tertiary care center during the peak of the COVID-19 pandemic in the hopes that knowledge of our experiences can benefit other pathology departments as they encounter this pandemic. Five categories that are critical in strategic planning for the COVID-19 pandemic are discussed: workload, departmental policy revisions, impact on faculty, workforce staffing, and impact on educational programs, including residency and fe

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Chipaila, Jackson, Alex Makupe, Evans Malyangu, Daniel Maswahu, Jane C. Kabwe, and Etienne BFK Odimba. "Diagnostic Accuracy of Fine needle Aspiration Cytology of Thyroid Nodules at two tertiary Hospitals in Zambia: a cross-sectional study." University of Zambia Journal of Agricultural and Biomedical Sciences 4, no. 2 (2020): 6–13. http://dx.doi.org/10.53974/unza.jabs.4.2.388.

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Introduction: Thyroid nodules are one of the common surgical presentations in Africa and are of great concern because of their potential to be malignant. Zambia is not excluded from these common surgical conditions. However, there are no pre-operative cellular or intra-operative tissue diagnoses of the thyroid nodules done before thyroidectomy making it difficult to plan for an optimal and definitive management. Fine needle aspiration cytology (FNAC) is known to play a pivotal role in the screening and management of thyroid swellings. This study serves to assess the diagnostic accuracy of FNAC

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Brotherton, Julia M. L., John R. Condon, Peter B. McIntyre, et al. "Human papillomavirus prevalence to age 60 years among Australian women prevaccination." Sexual Health 12, no. 4 (2015): 353. http://dx.doi.org/10.1071/sh15035.

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Background The prevalence of human papillomavirus (HPV) at the cervix varies with age, peaking following sexual debut and declining thereafter in most populations. In some populations, a second peak is observed. Here we describe the prevalence of HPV at the cervix among Australian women before the commencement of the HPV vaccination program. Methods: Women aged 15 to 60 years attending health services for cervical screening between 2005 and 2008 were invited to participate. Liquid based cervical specimens were tested for 37 types of HPV using linear array. The percentage and 95% confidence int

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Schiffman, Mark, and Philip E. Castle. "Human Papillomavirus: Epidemiology and Public Health." Archives of Pathology & Laboratory Medicine 127, no. 8 (2003): 930–34. http://dx.doi.org/10.5858/2003-127-930-hpeaph.

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Abstract Approximately 15 types of human papillomavirus (HPV) infection cause virtually all cases of cervical cancer. Human papillomavirus 16 is the major type, accounting for approximately 50% of cases. The major steps of cervical carcinogenesis include HPV infection, viral persistence and progression to precancer (as opposed to viral clearance), and invasion. Human papillomavirus is the most common sexually transmitted infection. However, most HPV infections become undetectable by even sensitive HPV DNA testing within 1 to 2 years. The prevalence of infection peaks at young ages and declines

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Gilg, Magdalena Maria, Bernadette Liegl, Christine Wibmer, Werner Maurer-Ertl, and Andreas Leithner. "Central low-grade osteosarcoma with an unusual localization in the diaphysis of a 12-year old patient." Radiology and Oncology 47, no. 2 (2013): 192–96. http://dx.doi.org/10.2478/raon-2013-0015.

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Background. Low-grade central osteosarcoma is a very rare subtype of osteosarcoma with a predilection for the metaphysis of long bones and a peak incidence in the 3rd decade of life. Absence of specific clinical symptoms and a good prognosis after wide resection are the characteristics of this entity. Chemotherapy is not indicated in this highly differentiated tumour. Case report. A 12-year old girl presented with limping, swelling and pain in the mid of the left femur. Radiography showed a 12 cm long intraosseous expansion with lamellated periosteal reaction and contrast medium enhancement in

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Medlock, ES, DL Kaplan, M. Cecchini, TR Ulich, J. del Castillo, and J. Andresen. "Granulocyte colony-stimulating factor crosses the placenta and stimulates fetal rat granulopoiesis." Blood 81, no. 4 (1993): 916–22. http://dx.doi.org/10.1182/blood.v81.4.916.916.

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Abstract We studied the effect of recombinant human granulocyte colony- stimulating factor (rhG-CSF) administration to pregnant rats upon fetal and neonatal myelopoiesis. Pregnant rats were treated with rhG-CSF twice daily for 2, 4, and 6 days before parturition. rhG-CSF crossed the placenta and reached peak fetal serum concentrations 4 hours after administration. Peak fetal serum levels were 1,000-fold lower than levels detected in the dam. Hematopoietic effects of rhG-CSF were assessed by cytologic analysis of the newborn blood, spleen, bone marrow, thymus, and liver. White blood cell counts

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Medlock, ES, DL Kaplan, M. Cecchini, TR Ulich, J. del Castillo, and J. Andresen. "Granulocyte colony-stimulating factor crosses the placenta and stimulates fetal rat granulopoiesis." Blood 81, no. 4 (1993): 916–22. http://dx.doi.org/10.1182/blood.v81.4.916.bloodjournal814916.

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We studied the effect of recombinant human granulocyte colony- stimulating factor (rhG-CSF) administration to pregnant rats upon fetal and neonatal myelopoiesis. Pregnant rats were treated with rhG-CSF twice daily for 2, 4, and 6 days before parturition. rhG-CSF crossed the placenta and reached peak fetal serum concentrations 4 hours after administration. Peak fetal serum levels were 1,000-fold lower than levels detected in the dam. Hematopoietic effects of rhG-CSF were assessed by cytologic analysis of the newborn blood, spleen, bone marrow, thymus, and liver. White blood cell counts were inc

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Morimoto, Yuki, Takeshi Oya, Mayuko Ichimura-Shimizu, et al. "Applying Probe Electrospray Ionization Mass Spectrometry to Cytological Diagnosis: A Preliminary Study by Using Cultured Lung Cancer Cells." Acta Cytologica 65, no. 5 (2021): 430–39. http://dx.doi.org/10.1159/000516639.

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<b><i>Objectives:</i></b> Cytology and histology are 2 indispensable diagnostic tools for cancer diagnosis, which are rapidly increasing in importance with aging populations. We applied mass spectrometry (MS) as a rapid approach for swiftly acquiring nonmorphological information of interested cells. Conventional MS, which primarily rely on promoting ionization by pre-applying a matrix to cells, has the drawback of time-consuming both on data acquisition and analysis. As an emerging method, probe electrospray ionization-MS (PESI-MS) with a dedicated probe is capable to p

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Tutchenko, T. M., O. A. Burka, I. F. Boyarchuk, A. V. Trampolska, V. V. Iavniuk, and L. S. Ostroukh. "Epidemiological and clinical trends of sexually transmitted infections. Literature review." Reproductive Endocrinology, no. 58 (May 27, 2021): 55–62. http://dx.doi.org/10.18370/2309-4117.2021.58.55-62.

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This article presents modern data on epidemiological trends, pathogenesis, and mechanisms of persistence and acquisition of antibiotic resistance of the most common sexually transmitted infections (STIs): chlamydial infection, gonorrhea, trichomoniasis. Data on the frequency of chlamydial infection, gonorrhea, trichomoniasis detection in the DILA medical laboratory in the period from 2018–2020 are also presented.Analysis of epidemiological and microbiological studies indicates a significant increase in the STIs incidence in countries with high economic development and the need for constant rev

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Kim, S., E. Chatelut, J. C. Kim, et al. "Extended CSF cytarabine exposure following intrathecal administration of DTC 101." Journal of Clinical Oncology 11, no. 11 (1993): 2186–93. http://dx.doi.org/10.1200/jco.1993.11.11.2186.

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PURPOSE The aims of the present study were to determine ventricular and lumbar CSF pharmacokinetics and the maximum-tolerated dose (MTD) of DTC 101 (DepoFoam; DepoTech Corp, La Jolla, CA) following intraventricular administration. PATIENTS AND METHODS Twelve patients with neoplastic meningitis were treated with escalating doses of DTC 101. CSF samples were obtained from the right lateral ventricle or from the lumbar subarachnoid space and cytarabine concentrations were determined by high-performance liquid chromatography. RESULTS Therapeutic ventricular CSF concentrations were maintained for 9

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Chauhan, Sima, and Simanta Kumar Behera. "FNAC as a Diagnostic Tool in the Evaluation of Cytomorphological Spectrum of Peripheral Lymphadenopathy along with Histopathological Agreement - An Experience in a Tertiary Teaching Hospital of Northern India." Journal of Evidence Based Medicine and Healthcare 7, no. 49 (2020): 2937–42. http://dx.doi.org/10.18410/jebmh/2020/601.

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BACKGROUND Lymphadenopathy is one of the commonest presentations in clinical practice. Fine Needle Aspiration Cytology (FNAC) is an established, easy, cost effective, diagnostic tool for lymphadenopathies. Judicious application of FNAC can avoid the need of biopsy. We wanted to compare the accuracy of FNAC and histological analysis of peripheral lymphadenopathy among patients visiting the Departments of Oncology, Pathology, Surgery of K.D. Medical College and determine the most prevalent cause of peripheral lymphadenopathy among different age groups of patients. METHODS This study was done amo

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Arif, NUM, AU Shaikh, B. Ranen, and Z. Waheed. "Diagnosis of Testicular Choriocarcinoma: A Case Study." Bangladesh Medical Journal 40, no. 2 (2014): 60–62. http://dx.doi.org/10.3329/bmj.v40i2.18514.

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Testicular cancer, although relatively rare, is the most common malignancy in men at the age of 15 to 35 years. Germ cell tumor (GCT) is the most common testicular tumor (90%-95%) and peak age of incidence is between 20 years to 50 years. Choriocarcinoma is very rare in male as a pure testicular tumor (<1%) but may be seen as a component of mixed GCT. These tumors characteristically secrete hCG (human chorionic gonadotrophin) into the serum, which use as an important serum tumor marker for these tumors. A 30 years old male presented to us with the complaints of hard feeling of the left test

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Ulyanovskaya, Y. V. "USE OF THE APPLE GENE POOL OF NORTH CAUCASUS FEDERAL SCIENTIFIC CENTER OF HORTICULTURE, VITICULTURE, WINEMAKING FOR THE BREEDING IMPROVEMENT OF THE SOUTHERN SORTIMENT." Pomiculture and small fruits culture in Russia 66, no. 1 (2021): 30–41. http://dx.doi.org/10.31676/2073-4948-2021-66-30-41.

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The objects of research are representatives of the genus Malus growing in the Kuban zone of the North Caucasus region. The purpose of the research is the breeding improvement of the of apple southern assortment on the basis of the development of the scientific direction “Introduction, variety study and breeding of pome crops in the North Caucasus and the creation of promising domestic varieties with improved adaptability and quality. The history of the creation and development of this scientific direction of the scientific school “Southern Horticulture” in the North Caucasus, the founder of wh

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Lee, J. S., R. A. Newman, S. M. Lippman, et al. "Phase I evaluation of all-trans-retinoic acid in adults with solid tumors." Journal of Clinical Oncology 11, no. 5 (1993): 959–66. http://dx.doi.org/10.1200/jco.1993.11.5.959.

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PURPOSE Prompted by recent demonstrations that all-trans-retinoic acid (all-trans-RA) had efficacy in acute promyelocytic leukemia, a phase I trial of all-trans-RA was conducted to establish the maximum-tolerated dose (MTD) before phase II testing. PATIENTS AND METHODS Forty patients with a histologic or cytologic diagnosis of malignancy other than leukemia were treated with single daily oral doses of all-trans-RA ranging from 45 mg/m2 to 200 mg/m2. Doses of all-trans-RA were escalated in the next cohort of patients until the MTD was determined if the preceding dose level was not associated wi

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Tiron, O. I., O. L. Appelhans, I. V. Gunas, and I. L. Chereshniuk. "Indicators of the cell cycle in the thyroid gland in rats when applying infusion of 0.9% solution of NaCl, lactoprotein with sorbitol or HAES-LX 5%." Reports of Morphology 25, no. 1 (2019): 62–67. http://dx.doi.org/10.31393/morphology-journal-2019-25(1)-09.

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The thyroid gland is an important organ that is involved in the regulation of homeostasis and adaptation in various pathological conditions. However, the question of the study of the proliferative activity of thyroid cells by flow cytometry is still poorly understood. Purpose of study: to investigate the indices of the cell cycle and DNA fragmentation of thyroid cells in rats against the background of infusion of 0.9% NaCl solution, lactoprotein with sorbitol or HAES-LX 5%. Experimental studies were performed on 90 white male rats weighing 160-180 g. Infusion of 0.9% NaCl solution, lactoprotei

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Eilts, B. E., J. A. Len, C. E. Pope, et al. "174 TRANSCERVICAL EMBRYO COLLECTION IN THE DOMESTIC BITCH." Reproduction, Fertility and Development 22, no. 1 (2010): 245. http://dx.doi.org/10.1071/rdv22n1ab174.

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Embryo collection in the bitch is usually performed via surgical collection or uterine excision. Our objective was to collect embryos nonsurgically, or with minimal surgical invasion. Estrus was monitored using vaginal cytology and progesterone analysis during 1 natural cycle and 13 cycles induced by the submucosal insertion of a 2.1-mg deslorelin implant into the vestibulum of Walker-type hounds (n = 10, 30 kg). Bitches (n = 14 cycles) were transcervically inseminated twice in 12 cycles, (3.3 and 5.2 days post-LH) and once on 2 cycles (Day 6 post-LH) with fresh semen. Uterine flushes (n = 14)

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Kadoch, Cigall, Marc A. Shuman, and James L. Rubenstein. "Complement Activation and Resistance within the Cerebrospinal Fluid Following Intraventricular Administration of Anti-CD20 in the Treatment of Recurrent CNS Lymphoma." Blood 110, no. 11 (2007): 3418. http://dx.doi.org/10.1182/blood.v110.11.3418.3418.

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Abstract We recently conducted the first phase I dose escalation study of intraventricular rituximab (anti-CD20 antibody) in patients with recurrent central nervous system (CNS) non-Hodgkin’s lymphoma (NHL). The goals of this study have been to define the safety and pharmacokinetics of intraventricular rituximab monotherapy and to gain insight into the molecular basis of rituximab efficacy and resistance in the treatment of high-grade lymphomas. We observed a rapid lymphocytotoxic effect of intraventricular rituximab administration in six out of ten subjects treated, resulting in four complete

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Haen, Sebastian P., Michael Schumm, Wichard Vogel, et al. "Haploidentical TCRab Depleted Hematopoietic Cell Transplantation Leads To Rapid Immune Reconstitution and Promising Clinical Outcome In Adults." Blood 122, no. 21 (2013): 5475. http://dx.doi.org/10.1182/blood.v122.21.5475.5475.

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Abstract Immunomagnetic TCRab-depletion and reduced intensity conditioning (RIC) for haploidentical hematopoietic cell transplantation (HHCT) has been reported to result in improved immune reconstitution and clinical outcome in children. We here report the first clinical results in 10 adult patients. HHCT using TCRab-depleted grafts was performed in 7 men and 3 women (median age at transplantation 35 years, range 21-68 years). Patients were treated for ALL (n=1), AML (n=5), CLL (n=1), NHL (n=2) or SAA (n=1). Disease status prior transplantation was CR in two patients, minimal residual disease

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