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Journal articles on the topic 'Penicilina V'

Author: Grafiati

Published: 4 June 2021

Last updated: 5 February 2022

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1

Marušič, Alenka, Igor Locatelli, and Aleš Mrhar. "Pharmacokinetics of penicillin antibiotics: intravenous-to-oral switch therapy." Slovenian Journal of Public Health 49, no. 4 (2010): 211–19. http://dx.doi.org/10.2478/v10152-010-0022-9.

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Farmakokinetika Penicilinskih Antibiotikov: Preklop iz Intravenske na Peroralno Terapijo Penicilinski antibiotiki delujejo baktericidno in spadajo med časovno odvisne antibiotike. Za večino penicilinov je značilna kratka razpolovna doba eliminacije. Benzilpenicilini se po peroralni aplikaciji ne absorbirajo, ampicilin in kloksacilin se sicer absorbirata, vendar slabo, medtem ko se amoksicilin skoraj v celoti absorbira. Pri slednjem je smotrno z intravenske terapije preklopiti na peroralno, če lahko s peroralno aplikacijo dosežemo plazemske koncentracije penicilina, primerljive s tistimi po int

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2

Polonevich, A. G., S. M. Leschev, A. I. Palianskikh, and L. L. Belyshava. "Extraction sample preparation for chromatographic determination of residual quantities of acidic penicillins in milk." Proceedings of the National Academy of Sciences of Belarus, Chemical Series 57, no. 3 (2021): 286–93. http://dx.doi.org/10.29235/1561-8331-2021-57-3-286-.

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The distribution of six acid-type penicillins (penicillin G, penicillin V, oxacillin, cloxacillin, nafcillin, dicloxacillin) in the extraction systems of chloroform–aqueous solutions of ammonium sulfate was studied. The reported distribution coefficients values of penicillins demonstrated the effectiveness of using ammonium sulfate as a salting-out agent. Based on the data obtained, a procedure for milk sample preparation was developed for the quantification of the residual content of six acid-type penicillins.

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3

Brito, Maria Aparecida Vasconcelos Paiva, José Renaldi Feitosa Brito, and Cátia Silene Klein. "CARACTERIZAÇÃO BIOQUÍMICA DE AMOSTRAS DE Haemophilus parasuis ISOLADAS DE SUÍNOS NA REGIÃO SUL DO BRASIL." Ciência Rural 24, no. 3 (1994): 557–61. http://dx.doi.org/10.1590/s0103-84781994000300019.

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O objetivo deste trabalho foi caracterizar amostras não hemolíticas de bactérias do gênero Haemophilus isoladas de suínos. As bactérias foram isoladas de material clínico de animais com suspeita da doença de Glässer, de leitões aparentemente sadios provenientes de quatro rebanhos com suspeita clínica desta doença e de casos de poliartrites. Além das características culturais e morfotintoriais, foram utilizados os seguintes testes para a identificação: dependência de NAD(fator V), CAMP, produção de hemolisina, indol, urease e catalase, redução do nitrato e produção de ácido dos carboidratos: gl

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4

Wolfe, Saul, Maged Khalil, and Donald Fredric Weaver. "MMPEN: Development and evaluation of penicillin parameters for Allinger's MMP2(85)programme." Canadian Journal of Chemistry 66, no. 11 (1988): 2715–32. http://dx.doi.org/10.1139/v88-423.

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A set of parameters, termed MMPEN, has been determined for the bicyclic nucleus of penicillin, which, in conjunction with the appropriate parameters from MMPEP and the internally stored parameters of the program, allow Allinger's force field and MMP2(85) program to be applied to the molecular mechanics treatment of penicillins. The MMPEN parameters are based on crystallographic heavy atom bond lengths and bond angles, vibrational spectra, and molecular orbital calculations. The parameters reproduce the experimental crystal structures of several penicillins, including penicillin G and penicilli

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5

Iskandar, Burhanuddin, Bambang Madiyono, Sudigdo Sastroasmoro, Sukman T. Putra, Mulyadi M. Djer, and Anis Karuniawati. "Comparison of minimal inhibitory and bactericidal capacity of oral penicillin V with benzathine penicillin G to Streptococcus beta--hemolyticus group A in children with rheumatic heart disease." Paediatrica Indonesiana 48, no. 3 (2016): 152. http://dx.doi.org/10.14238/pi48.3.2008.152-5.

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Background Injection ofbenzatine penicillin G (BPG) every 28days is still the drug of choice for secondary prevention of rheu-matic heart disease (RHD). BPG sometimes poses problems dueto pain at the injection site, possible anaphylaxis, and is not alwaysavailable. Some centers choose oral penicillin over BPG.Objectives To compare minimal inhibitory capacity (MIC) andminimal bactericidal capacity (MBC) of oral penicillin V serumwith those of BPG among SGA infected RHD.Methods This was a clinical trial with crossover design study tocompare MIC of penicillin V and BPG. Outcome measures wereMIC a

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6

Torres-Bacete, Jesús, Daniel Hormigo, Maribel Stuart, et al. "Newly Discovered Penicillin Acylase Activity of Aculeacin A Acylase from Actinoplanes utahensis." Applied and Environmental Microbiology 73, no. 16 (2007): 5378–81. http://dx.doi.org/10.1128/aem.00452-07.

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ABSTRACT Aculeacin A acylase from Actinoplanes utahensis produced by Streptomyces lividans revealed acylase activities that are able to hydrolyze penicillin V and several natural aliphatic penicillins. Penicillin K was the best substrate, showing a catalytic efficiency of 34.79 mM−1 s−1. Furthermore, aculeacin A acylase was highly thermostable, with a midpoint transition temperature of 81.5°C.

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7

Moats, William A., and Rainer Malisch. "Determination of Cloxacillin and Penicillin V in Milk Using an Automated Liquid Chromatography Cleanup." Journal of AOAC INTERNATIONAL 75, no. 2 (1992): 257–60. http://dx.doi.org/10.1093/jaoac/75.2.257.

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Abstract A number of screening tests will detect β-lactam antibiotics at levels of less than 10 ng/mL in milk. However, confirmatory procedures of comparable sensitivity are not available. A method using an automated liquid chromatography (LC) cleanup sensitive to 1 ng/mL was developed for penicillin V and cloxacillin. Milk was deproteinlzed with 2 volumes of acetonitrlle. Methylene chloride and hexane were added to the filtrate to separate the water layer containing the antibiotics. The filtrate could also be evaporated directly. The water layer was concentrated and loaded onto a polymeric LC

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8

Rivillas-García, Juan Carlos, Sandra Marcela Sanchez, and Danny Rivera-Montero. "Desigualdades sociales relacionadas con la resistencia a antimicrobianos de N. gonorrhoeae en Colombia." Revista Panamericana de Salud Pública 44 (September 23, 2020): 1. http://dx.doi.org/10.26633/rpsp.2020.49.

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Objetivo. Medir desigualdades sociales en la resistencia antimicrobiana de la Neisseria gonorrhoeae en Colombia. Médos. Estudio ecológico utilizando un multipanel de datos desagregado a nivel subnacional de los aislamientos en la N. gonorrhoeae como proxy de resistencia antimicrobiana (RAM) entre 2009 y 2018. Se llevó a cabo una caracterización sociodemográfica, un análisis de la sensibilidad antimicrobiana de aislamientos de N. gonorrhoeae, y una medición de desigualdades en la RAM para la N. gonorrhoeae mediante el índice de desigualdad de la pendiente, el índice de desigualdad relativo y el

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9

Kuehn, Jemima, Zareen Ismael, Paul F. Long, Charlotte I. S. Barker, and Mike Sharland. "Reported Rates of Diarrhea Following Oral Penicillin Therapy in Pediatric Clinical Trials." Journal of Pediatric Pharmacology and Therapeutics 20, no. 2 (2015): 90–104. http://dx.doi.org/10.5863/1551-6776-20.2.90.

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OBJECTIVES: Antibiotic-associated diarrhea (AAD) is a well-recognized adverse reaction to oral penicillins. This review analyzed the literature to determine the incidence of AAD following amoxicillin, amoxicillin/clavulanate, and penicillin V oral therapy in pediatric clinical trials. METHODS: An advanced search was conducted in MEDLINE and Embase databases for articles in any language reporting the incidence of AAD following oral penicillin therapy for any indicated infection in children (0–17 years). The search was limited to clinical trials. Articles were excluded if treatment was related t

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10

Fabjan Vodušek, Vesna, Lilijana Kornhauser Cerar, Helena Mole, et al. "Antibiotična terapija ob porodu – priporočila." Slovenian Medical Journal 88, no. 1-2 (2019): 93–102. http://dx.doi.org/10.6016/zdravvestn.2916.

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Antibiotike v času poroda uporabljamo za preprečevanje in zdravljenje okužb pri materi ter za preprečevanje okužb pri novorojenčkih. Kratkotrajna terapija med porodom se uporablja za preprečevanje okužb s streptokokom skupine B (SSB) pri novorojenčkih, poporodnega endometritisa in za zdravljenje horioamnionitisa. Številne raziskave so dokazale, da z uporabo profilaktičnih odmerkov antibiotikov lahko podaljšamo nosečnost (in nato izboljšamo rezultate obolevnosti in umrljivosti novorojenčkov) po predčasnem prezgodnjem razpoku plodovih jajčnih ovojev (PPROM).  Pri nosečnicah z aktivnim prez

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11

Thornhill, M. H., M. J. Dayer, M. J. Durkin, P. B. Lockhart, and L. M. Baddour. "Risk of Adverse Reactions to Oral Antibiotics Prescribed by Dentists." Journal of Dental Research 98, no. 10 (2019): 1081–87. http://dx.doi.org/10.1177/0022034519863645.

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Dentists prescribe a large portion of all oral antibiotics, and these are associated with a risk of adverse drug reactions (ADRs). The aim of this study was to quantify the risk of ADRs associated with oral antibiotics commonly prescribed by dentists. NHS Digital Prescribing data and Yellow Card Drug Analysis data for 2010 to 2017 were abstracted to quantify dental antibiotic prescribing in England, and the rate and types of ADRs associated with them. During the period of study, the mean number of actively practicing dentists in England was 23,624. Amoxicillin accounted for 64.8% of dental ant

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12

Díaz-Bao, Mónica, Rocío Barreiro, José Manuel Miranda, Alberto Cepeda, and Patricia Regal. "Fast HPLC-MS/MS Method for Determining Penicillin Antibiotics in Infant Formulas Using Molecularly Imprinted Solid-Phase Extraction." Journal of Analytical Methods in Chemistry 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/959675.

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The dairy cattle may suffer from different infections relatively often, but the inflammation of the mammary gland is very important to the farmer. These infections are frequently treated with penicillin antimicrobial drugs. However, their use may result in the presence of residues in animal products, such as milk powder and/or infant formulas, and it represents a potential risk for consumers. To monitor this, the EU has defined safe maximum residue limits (MRLs) through Commission Regulation (EU) number 37/2010. Although LC-MS is a trustful option for confirmation and quantification of antibio

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13

Wolfe, Saul, Kiyull Yang, and Maged Khalil. "Conformation–activity relationships and the mechanism of action of penicillin." Canadian Journal of Chemistry 66, no. 11 (1988): 2733–50. http://dx.doi.org/10.1139/v88-424.

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Using the MMPEN parameters of Allinger's MMP2(85) force field, a conformational analysis has been performed on four biologically active penicillins; D-ampicillin, L-α-phenoxyethylpenicillin, penicillin G, and penicillin V, and on five biologically inactive or much less active penicillins: L-ampicillin, D-α-phenoxyethylpenicillin, N-methylpenicillin G, 6α-methylpenicillin G, and bisnorpenicillin G. Antibacterial activity is found to be associated with the existence of a global minimum having a compact structure, whose convex face is accessible to a penicillin binding protein (PBP), with the C3-

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14

Dwivedi, Deepak, Tejram Kushwah, Mukesh Kushwah, and Vinod Singh. "Antibiotic susceptibility pattern against pathogenic bacteria causing Dental Caries." South Asian Journal of Experimental Biology 1, no. 1 (2011): 31–35. http://dx.doi.org/10.38150/sajeb.1(1).p31-35.

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Antibiotics to treat dental caries infection are routinely prescribed which led to the increased resistance against bacteria. The purpose of this investigation was to perform antibiotic susceptibility tests on a panel of pathogenic bacteria isolated from dental caries infection. Bacteria were isolated from caries site of patients and identified at the species level. Each of 150 species of bacteria was tested for antibiotics susceptibility to a five antibiotics using Etest. The antibiotics used were Amoxicillin, Cloxocillin, Erythromycin, Tetracycline and PenicillinÃ¢â‚¬ÂV. The obtained resist

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15

Boison, Joe O., and Lily J. Y. Keng. "Multiresidue Liquid Chromatographic Method for Determining Residues of Mono- and Dibasic Penicillins in Bovine Muscle Tissues." Journal of AOAC INTERNATIONAL 81, no. 6 (1998): 1113–20. http://dx.doi.org/10.1093/jaoac/81.6.1113.

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Abstract A liquid chromatographic method with UV detection at 325 nm was developed for simultaneous determination of amoxicillin, ampicillin, penicillin G, and cloxacillin residues in bovine muscle tissue as their mercaptide derivatives. The penicillins are extracted from bovine tissues with 0.1 M phosphate buffer (pH 8.5), cleaned up on a t-C18 Sep-Pak cartridge, and eluted with 2 ml acetonitrile. After the acetonitrile in the eluate is evaporated to dryness, the residue is dissolved in 200 |µL (40 + 60, v/v) aceton itrile-phosphate buffer (pH 6.5) and derivatized with acetic anhydride and me

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16

Serrano-Aguirre, Lara, Rodrigo Velasco-Bucheli, Begoña García-Álvarez, Ana Saborido, Miguel Arroyo, and Isabel de la Mata. "Novel Bifunctional Acylase from Actinoplanes utahensis: A Versatile Enzyme to Synthesize Antimicrobial Compounds and Use in Quorum Quenching Processes." Antibiotics 10, no. 8 (2021): 922. http://dx.doi.org/10.3390/antibiotics10080922.

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Many intercellular communication processes, known as quorum sensing (QS), are regulated by the autoinducers N-acyl-l-homoserine lactones (AHLs) in Gram-negative bacteria. The inactivation of these QS processes using different quorum quenching (QQ) strategies, such as enzymatic degradation of the autoinducers or the receptor blocking with non-active analogs, could be the basis for the development of new antimicrobials. This study details the heterologous expression, purification, and characterization of a novel N-acylhomoserine lactone acylase from Actinoplanes utahensis NRRL 12052 (AuAHLA), wh

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17

MATELOVÁ, V. "Control of growth and penicillin biosynthesis of production strain during initial hours of fermentation." Kvasny Prumysl 31, no. 9 (1985): 206–8. http://dx.doi.org/10.18832/kp1985053.

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18

SOBACK, S., B. KURTZ, and G. ZIV. "Pharmacokinetics of phenoxymethyl penicillin (penicillin V) in calves." Journal of Veterinary Pharmacology and Therapeutics 10, no. 1 (1987): 17–22. http://dx.doi.org/10.1111/j.1365-2885.1987.tb00071.x.

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19

Kosnik, Mitja, Mira Silar, Mihaela Zidarn, and Petar Korosec. "Comparison of the diagnostic value of two assays for specific immunoglobulin E in suspected beta lactam allergy." Medical review 70, no. 7-8 (2017): 209–15. http://dx.doi.org/10.2298/mpns1708209k.

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Introduction. The aim of this study was to compare the diagnostic value of two imunoglobulin E assays for penicillin in a group of patients with a history compatible with hypersensitivity reaction during penicillin treatment who exhibited positive skin testing and/or a drug provocation testing. Material and Methods. In the first part of the study, penicillin G, V and/or amoxicillin specific immunoglobulin E, positive with ImmunoCAP system (Termo Fisher, Waltham, Massachusetts, USA), were selected from our biobank sera, and measured specific immunoglobulin E with Immulite system (Siemens, Munic

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20

Anderer, T. "Review: penicillin V is better than placebo and equal to non-penicillins for acute maxillary sinusitis." Evidence-Based Nursing 3, no. 2 (2000): 49. http://dx.doi.org/10.1136/ebn.3.2.49.

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21

Baldwin, Jack E., Edward P. Abraham, Geoffrey L. Burge, and Hong-Hoi Ting. "Penicillin biosynthesis: direct biosynthetic formation of penicillin V and penicillin G." Journal of the Chemical Society, Chemical Communications, no. 24 (1985): 1808. http://dx.doi.org/10.1039/c39850001808.

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22

Brent Cole, L., and Elizabeth M. Holt. "Calcium complexation to penicillin V." Inorganica Chimica Acta 137, no. 3 (1987): 137–38. http://dx.doi.org/10.1016/s0020-1693(00)81155-x.

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23

eo. "Bei Lues: Penicillin i. v.!" MMW - Fortschritte der Medizin 158, S2 (2016): 12. http://dx.doi.org/10.1007/s15006-016-8319-5.

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24

Ecke, Alexander, та Rudolf J. Schneider. "Pitfalls in the Immunochemical Determination of β-Lactam Antibiotics in Water". Antibiotics 10, № 3 (2021): 298. http://dx.doi.org/10.3390/antibiotics10030298.

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Contamination of waters with pharmaceuticals is an alarming problem as it may support the evolution of antimicrobial resistance. Therefore, fast and cost-effective analytical methods for potential on-site analysis are desired in order to control the water quality and assure the safety of its use as a source of drinking water. Antibody-based methods, such as the enzyme-linked immunosorbent assay (ELISA), can be helpful in this regard but can also have certain pitfalls in store, depending on the analyte. As shown here for the class of β-lactam antibiotics, hydrolysis of the β-lactam ring is a ke

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25

Chang, L. T., E. L. McGrory, R. P. Elander, and D. J. Hook. "Decreased production ofpara-hydroxypenicillin V in penicillin V fermentations." Journal of Industrial Microbiology 7, no. 3 (1991): 175–79. http://dx.doi.org/10.1007/bf01575880.

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26

Sparandero, F. "Review: penicillin V or amoxicillin is better than placebo and equal to non-penicillins for acute maxillary sinusitis." Evidence-Based Medicine 5, no. 2 (2000): 43. http://dx.doi.org/10.1136/ebm.5.2.43.

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27

Yoon, T. S., and W. Shin. "Penicillin V Benzhydryl Ester Sulfoxide Monohydrate." Acta Crystallographica Section C Crystal Structure Communications 52, no. 12 (1996): 3142–44. http://dx.doi.org/10.1107/s0108270196009250.

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28

Onate, J., M. Montejo, K. Aguirrebengoa, G. Ruiz-Irastorza, P. G. de Zarate, and C. Aguirre. "Hepatotoxicity Associated with Penicillin V Therapy." Clinical Infectious Diseases 20, no. 2 (1995): 474–75. http://dx.doi.org/10.1093/clinids/20.2.474.

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29

Shin, W., and S. W. Cho. "Structure of penicillin V benzyl ester." Acta Crystallographica Section C Crystal Structure Communications 48, no. 8 (1992): 1447–49. http://dx.doi.org/10.1107/s0108270192000465.

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30

Thamlikitkul, V., S. Kobwanthanakun, S. Pruksachatvuthi, and R. Lertluknithi. "Pharmacokinetics of Rheumatic Fever Prophylaxis Regimens." Journal of International Medical Research 20, no. 1 (1992): 20–26. http://dx.doi.org/10.1177/030006059202000103.

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The pharmacokinetics of benzathine penicillin G (1200000 IU given intramuscularly), penicillin V (250 mg given orally twice daily), erythromycin stearate (250 mg given orally twice daily) and roxithromycin (150 mg given orally once daily) were investigated. The drugs were given prophylactically to prevent the recurrence of rheumatic fever to 20 patients attending a rheumatic fever clinic in a study of crossover design. Serum antibiotic concentrations were determined by microbiological assay at intervals of up to 28 days after intramuscular injection and immediately before and 1–2 h after the f

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31

Sudhakaran, V. K., and J. G. Shewale. "Enzymatic splitting of penicillin V for the production of 6-APA using immobilized penicillin V acylase." World Journal of Microbiology & Biotechnology 9, no. 6 (1993): 630–34. http://dx.doi.org/10.1007/bf00369569.

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32

Koetsier, Martijn J., Peter A. Jekel, Marco A. van den Berg, Roel A. L. Bovenberg, and Dick B. Janssen. "Characterization of a phenylacetate–CoA ligase from Penicillium chrysogenum." Biochemical Journal 417, no. 2 (2008): 467–76. http://dx.doi.org/10.1042/bj20081257.

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Enzymatic activation of PAA (phenylacetic acid) to phenylacetyl-CoA is an important step in the biosynthesis of the β-lactam antibiotic penicillin G by the fungus Penicillium chrysogenum. CoA esters of PAA and POA (phenoxyacetic acid) act as acyl donors in the exchange of the aminoadipyl side chain of isopenicillin N to produce penicillin G or penicillin V. The phl gene, encoding a PCL (phenylacetate–CoA ligase), was cloned in Escherichia coli as a maltose-binding protein fusion and the biochemical properties of the enzyme were characterized. The recombinant fusion protein converted PAA into p

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Hedberg, Sara Thulin, Hans Fredlund, Pierre Nicolas, Dominique A. Caugant, Per Olcén, and Magnus Unemo. "Antibiotic Susceptibility and Characteristics of Neisseria meningitidis Isolates from the African Meningitis Belt, 2000 to 2006: Phenotypic and Genotypic Perspectives." Antimicrobial Agents and Chemotherapy 53, no. 4 (2009): 1561–66. http://dx.doi.org/10.1128/aac.00994-08.

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ABSTRACT Up-to-date information regarding the antibiotic susceptibility of Neisseria meningitidis strains from African countries is highly limited. Our aim was to comprehensively describe the antibiotic susceptibilities of a selection of N. meningitidis isolates recovered between 2000 and 2006 from 18 African countries, mainly those within the meningitis belt. Susceptibilities to 11 antibiotics were determined using Etest for 137 N. meningitidis isolates (stringently selected from 693 available isolates). The isolates were also characterized by serogrouping, multilocus sequence typing, genosub

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Boison, Joe O. K., Lily J.-Y. Keng, and James D. Macneil. "Analysis of Penicillin G in Milk by Liquid Chromatography." Journal of AOAC INTERNATIONAL 77, no. 3 (1994): 565–70. http://dx.doi.org/10.1093/jaoac/77.3.565.

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Abstract A liquid chromatographic (LC) method that was previously developed for penicillin G residues in animal tissues has been adapted to milk and milk products. After protein precipitation with sodium tungstate, samples are applied to a C18 solid-phase extraction cartridge, from which penicillin is eluted, derivatized with 1,2,4-triazole-mercuric chloride solution, and analyzed by isocratic liquid chromatography (LC) on a C18 column with UV detection at 325 nm. Quantitation is done with reference to penicillin V as an internal standard. Penicillin G recoveries were determined to be &gt;

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Pacifico, L., F. Scopetti, A. Ranucci, M. Pataracchia, F. Savignoni, and C. Chiesa. "Comparative efficacy and safety of 3-day azithromycin and 10-day penicillin V treatment of group A beta-hemolytic streptococcal pharyngitis in children." Antimicrobial Agents and Chemotherapy 40, no. 4 (1996): 1005–8. http://dx.doi.org/10.1128/aac.40.4.1005.

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The efficacy and safety of a 3-day course of azithromycin oral suspension (10 mg/kg of body weight once daily) were compared with those of penicillin V (50,000 U/kg/day in two divided doses) in children aged 3 to 12 years for the treatment of symptomatic pharyngitis caused by the group A beta-hemolytic streptococcus (GABHS). For the 154 evaluable patients, the original infecting strain of GABHS was eliminated at the end of follow-up (34 to 36 days after treatment started) from 67 (85.8%) of 78 penicillin-treated patients and 41 (53.9%) of 76 azithromycin-treated patients (P < 0.0001). Overa

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Boison, Joe O., Craig D. C. Salisbury, Wayne Chan, and James D. Macneil. "Determination of Penicillin G Residues in Edible Animal Tissues by Liquid Chromatography." Journal of AOAC INTERNATIONAL 74, no. 3 (1991): 497–501. http://dx.doi.org/10.1093/jaoac/74.3.497.

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Abstract An Improved method has been developed for the determination of benzyl penicillin In animal tissues. Tissues are fortified with a known amount of penicillin V (Internal standard) and extracted with water. The extract Is deproteinlzed with sulfuric acid and sodium tungstate, filtered, and concentrated on a conditioned C18 solid phase extraction column. Penicillin V and benzyl penicillin are then eluted from the column with 1 mL 60% acetonitrile-35% water-5% 0.2M phosphate buffer solution and derivatlzed with 1 mL 1,2,4-trlazole-mercuric chloride solution at 65°C for 30 min. An aliquot o

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Mopper, Barry. "Liquid Chromatographic Determination of Penicillin V Potassium in Tablets and Powders for Oral Solution." Journal of AOAC INTERNATIONAL 70, no. 1 (1987): 39–41. http://dx.doi.org/10.1093/jaoac/70.1.39.

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Abstract A reverse-phase liquid chromatographic method is described for the assay of penicillin V potassium in tablets and powders for oral solution. Under isocratic conditions, the combined use of an octadecjrlsilane column, with a mobile phase composed of acetonitrile-methanol- O.OlM monobasic potassium phosphate (21 + 4 + 75, v/v), and photometric detection at 225 nm, separated penicillin V potassium from excipients, related compounds, and degradation products. Sulfadimethoxine was used as an internal standard. Detector responses were linearly related to concentrations of penicillin V over

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38

Brito, Roseane Brandão de, and Roberto Gonçalves Junqueira. "Determination of Beta-Lactam residues in milk by high performance liquid chromatography." Brazilian Archives of Biology and Technology 49, spe (2006): 41–46. http://dx.doi.org/10.1590/s1516-89132006000200007.

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A high performance liquid chromatographic method to assay beta-lactam residues in milk was developed and validated. Milk samples were spiked with standard solutions and deproteinated. The extract was cleaned-up on C18 SPE cartridge, the antibiotics eluted with acetonitrile:water (50:50 v/v) and derivatized with acetic anhydride and 1-methyl-imidazole solution containing HgCl2. The chromatographic analysis was performed on C18 column using mobile phase consisting of acetonitrile and phosphate buffer (pH 6.5) in the presence of Na2S2O3 gradient and detection at 325 nm. The method was selective f

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Taboada, Pablo, Martı́n Pérez-Rodrı́guez, Luis M. Varela, Silvia Barbosa, Manuel Garcı́a, and Vı́ctor Mosquera. "Permitivity of penicillin V: a thermodynamic study." Thermochimica Acta 394, no. 1-2 (2002): 39–43. http://dx.doi.org/10.1016/s0040-6031(02)00236-8.

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Brook, Itzhak. "Penicillin V and rifampin for streptococcal pharyngitis." Journal of Pediatrics 107, no. 5 (1985): 825. http://dx.doi.org/10.1016/s0022-3476(85)80437-6.

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Blanca, M., M. J. Carmona, F. Moreno, C. Mayorga, and J. Garcia. "Selective immediate allergic response to penicillin V." Allergy 51, no. 12 (1996): 961–63. http://dx.doi.org/10.1111/j.1398-9995.1996.tb04504.x.

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Shin, W., Jaheon Kim, and Joohyun Kim. "Structure of penicillin V benzyl ester sulfoxide." Acta Crystallographica Section C Crystal Structure Communications 48, no. 8 (1992): 1449–51. http://dx.doi.org/10.1107/s0108270192000477.

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Kerr, D. E. "A Colorimetric Assay for Penicillin-V Amidase." Analytical Biochemistry 209, no. 2 (1993): 332–34. http://dx.doi.org/10.1006/abio.1993.1129.

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Yang, Hu, and Stephanie T. Lopina. "Penicillin V-conjugated PEG-PAMAM star polymers." Journal of Biomaterials Science, Polymer Edition 14, no. 10 (2003): 1043–56. http://dx.doi.org/10.1163/156856203769231556.

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Santoso, Imam, Bachri Amran, and Apriliana Laily Fitri. "SEPARATION OF PENICILLIN G FROM FERMENTATION BROTH BY EMULSION LIQUID MEMBRANE TECHNIQUE." Indonesian Journal of Chemistry 10, no. 1 (2010): 46–50. http://dx.doi.org/10.22146/ijc.21496.

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The separation of penicillin G from fermentation broth can be done by emulsion liquid membrane technique. The aim of this research is to establish the optimal conditions for the extraction and separation of penicillin G using emulsion liquid membrane technique. The optimal conditions were found to be at ratio of internal phase volume to membrane phase volume of 1:1 ; time of making emulsion, 1 min ; emulsion contact rate, 300 rpm; rate of stirring of emulsion, 2000 rpm ; rest time of emulsion, 13 min; concentration of penicillin G as external phase, 375 ppm; and concentration of surfactant, 5%

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Daher, Omar, Horacio A. Lopardo, and Etelvina A. Rubeglio. "Value of Etest penicillin V and penicillin G strips for penicillin susceptibility testing of Neisseria meningitidis." Diagnostic Microbiology and Infectious Disease 43, no. 2 (2002): 119–21. http://dx.doi.org/10.1016/s0732-8893(02)00386-3.

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Smith, Louise, Elizabeth Ryan, Russell D. Keenan, and Rekha Thangavelu. "No Demonstrable Benefit of Penicillin in a Vaccinated Population of Children with Sickle Cell Disorder." Blood 132, Supplement 1 (2018): 4927. http://dx.doi.org/10.1182/blood-2018-99-119768.

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Abstract UK and many National guidelines advise on the use of prophylactic antibiotics, immunisation and patient education to minimise the risk of severe infections by encapsulated organisms in patients with Sickle Cell Disorder. The UK vaccination schedule for sickle cell anaemia patients includes Pneumococcal, Meningococcal and Haemophilus influenzae type B (Hib) immunisation. Prophylactic Penicillin V is recommended as additional protection against Streptococcus pneumoniae (S.pneumoniae). In light of the findings in the papers by Oligbu et al, 2017, and Martin et al 2018, we aimed to retros

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Fransson, Sara, Holger F. Mosbech, Jesper Elberling, Mogens Kappel, and Lene H. Garvey. "Intradermal Testing Identifies 1 in 4 Patients with Nonimmediate Penicillin Allergy." International Archives of Allergy and Immunology 182, no. 9 (2021): 827–34. http://dx.doi.org/10.1159/000515080.

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<b><i>Background:</i></b> Intradermal testing with delayed reading (IDTdr), used routinely in many centers, may identify delayed reactions to penicillins. However, few studies have compared the results of IDTdr with drug provocation test (DPT). The aim of this study was to examine the proportion of provocation-positive patients testing positive on IDTdr. <b><i>Methods:</i></b> Fifty-seven patients with a positive DPT occurring &#x3e;2 h after intake of penicillin V, dicloxacillin, pivampicillin, or amoxicillin had an IDTdr with penicillin G,

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Hertz, Frederik Boetius, Aksel Jensen, Jenny D. Knudsen, et al. "Does macrolide use confer risk of out-of-hospital cardiac arrest compared with penicillin V? A Danish national case-crossover and case–time–control study." BMJ Open 8, no. 2 (2018): e019997. http://dx.doi.org/10.1136/bmjopen-2017-019997.

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Introduction and objectivesMacrolides have been associated with proarrhythmic properties, but the evidence is conflicting. We evaluated the risk of out-of-hospital cardiac arrest (OHCA) associated with specific macrolides in a retrospective study. Associations between specific macrolides and OHCA were examined by conditional logistic regression analyses in case-crossover and case–time–control models, using penicillin-V treatment as the comparative reference. From nationwide registries, we identified all OHCAs in Denmark from 2001 to 2010 and use of antibiotics.EthicsThe present study was appro

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Sigl, Claudia, Hubertus Haas, Thomas Specht, Kristian Pfaller, Hubert Kürnsteiner, and Ivo Zadra. "Among Developmental Regulators, StuA but Not BrlA Is Essential for Penicillin V Production inPenicillium chrysogenum." Applied and Environmental Microbiology 77, no. 3 (2010): 972–82. http://dx.doi.org/10.1128/aem.01557-10.

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ABSTRACTIn filamentous fungi, secondary metabolism is often linked with developmental processes such as conidiation. In this study we analyzed the link between secondary metabolism and conidiation in the main industrial producer of the β-lactam antibiotic penicillin, the ascomycetePenicillium chrysogenum. Therefore, we generated mutants defective in two central regulators of conidiation, the transcription factors BrlA and StuA. Inactivation of eitherbrlAorstuAblocked conidiation and altered hyphal morphology during growth on solid media, as shown by light and scanning electron microscopy, but

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