Academic literature on the topic 'Penicillin G Penicillin G'

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Journal articles on the topic "Penicillin G Penicillin G"

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Higazi, Abd Al-Roof, and Michael Mayer. "In Vitro Inhibition of Urokinase by Penicillins." Thrombosis and Haemostasis 60, no. 02 (1988): 305–7. http://dx.doi.org/10.1055/s-0038-1647049.

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SummaryUrokinase activity was assayed by a two-stage globinolytic method and by a direct chromogenic assay. With both methods, the enzyme activity was found to be inhibited by penicillins. The inhibition by penicillin G, carbenicillin, cloxacillin and penicilloic acid was dose-dependent. The Kj of penicillin G and urokinase with the S-2444 as substrate is 4 mM. This compound exhibited a competitive pattern of inhibition. Ampicillin and 6-amino penicillanic acid failed to inhibit urokinase. These results imply that hydrophobic side chains of penicillins interact with the active site of urokinas
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Wolfe, Saul, Maged Khalil, and Donald Fredric Weaver. "MMPEN: Development and evaluation of penicillin parameters for Allinger's MMP2(85)programme." Canadian Journal of Chemistry 66, no. 11 (1988): 2715–32. http://dx.doi.org/10.1139/v88-423.

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A set of parameters, termed MMPEN, has been determined for the bicyclic nucleus of penicillin, which, in conjunction with the appropriate parameters from MMPEP and the internally stored parameters of the program, allow Allinger's force field and MMP2(85) program to be applied to the molecular mechanics treatment of penicillins. The MMPEN parameters are based on crystallographic heavy atom bond lengths and bond angles, vibrational spectra, and molecular orbital calculations. The parameters reproduce the experimental crystal structures of several penicillins, including penicillin G and penicilli
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Torres, Leticia L., Ángel Cantero, Mercedes del Valle, et al. "Engineering the Substrate Specificity of a Thermophilic Penicillin Acylase from Thermus thermophilus." Applied and Environmental Microbiology 79, no. 5 (2012): 1555–62. http://dx.doi.org/10.1128/aem.03215-12.

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ABSTRACTA homologue of theEscherichia colipenicillin acylase is encoded in the genomes of several thermophiles, including in differentThermus thermophilusstrains. Although the natural substrate of this enzyme is not known, this acylase shows a marked preference for penicillin K over penicillin G. Three-dimensional models were created in which the catalytic residues and the substrate binding pocket were identified. Through rational redesign, residues were replaced to mimic the aromatic binding site of theE. colipenicillin G acylase. A set of enzyme variants containing between one and four amino
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Kaplan, Edward L. "Benzathine Penicillin G." Pediatric Infectious Disease Journal 31, no. 7 (2012): 726–28. http://dx.doi.org/10.1097/inf.0b013e318259b75c.

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Wang, Jian. "Confirmatory Determination of Six Penicillins in Honey by Liquid Chromatography/Electrospray Ionization–Tandem Mass Spectrometry." Journal of AOAC INTERNATIONAL 87, no. 1 (2004): 45–55. http://dx.doi.org/10.1093/jaoac/87.1.45.

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Abstract A confirmatory method for 6 penicillin antibiotics (amoxicillin, ampicillin, penicillin G, oxacillin, cloxacillin, and dicloxacillin) in honey is presented that allows determination and confirmation of identity of the antibiotics at trace levels. The method includes the use of a stable isotope-labeled internal standard benzyl (d7-phenyl) penicillate and removal of sugar and other substances by solvent and solid-phase extraction. The honey extracts are then analyzed for penicillin residues by liquid chromatography/electrospray ionization–tandem mass spectrometry. Mass spectral acquisit
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Kado, Joseph H., Sam Salman, Robert Henderson, et al. "Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers." Journal of Antimicrobial Chemotherapy 75, no. 10 (2020): 2951–59. http://dx.doi.org/10.1093/jac/dkaa282.

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Abstract Background Benzathine penicillin G has been used as monthly deep intramuscular (IM) injections since the 1950s for secondary prevention of acute rheumatic fever and rheumatic heart disease (RHD). Injection frequency and pain are major programmatic barriers for adherence, prompting calls for development of better long-acting penicillin preparations to prevent RHD. We hypothesized that subcutaneous (SC) administration of benzathine penicillin G could delay penicillin absorption when compared with IM injections. Methods To compare the pharmacokinetic profile and tolerability of benzathin
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Kurzątkowski, Wieslaw, and Anita Gębska-Kuczerowska. "Pexophagy in Penicillin G Secretion by Penicillium chrysogenum PQ-96." Polish Journal of Microbiology 65, no. 3 (2016): 365–68. http://dx.doi.org/10.5604/17331331.1215616.

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Penicillin G oversecretion by Penicillium chrysogenum PQ-96 is associated with a strictly adjusted cellular organization of the mature and senescent mycelial cells. Abundant vacuolar phagy and extended cellular vacuolization combined with vacuolar budding resulting in the formation of vacuolar vesicles that fuse with the cell membrane are the most important characteristic features of those cells. We suggest as follows: if the peroxisomes are integrated into vacuoles, the penicillin G formed in peroxisomes might be transferred to vacuoles and later secreted out of the cells by an exocytosis pro
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KURZĄTKOWSKI, WIESŁAW, MONIKA STANISZEWSKA, MAŁGORZATA BONDARYK, and ANITA GĘBSKA-KUCZEROWSKA. "Compartmentalization in Penicillin G Biosynthesis by Penicillium chrysogenum PQ-96." Polish Journal of Microbiology 63, no. 4 (2014): 399–408. http://dx.doi.org/10.33073/pjm-2014-054.

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The arrangement of organelles in the sub-apical productive non-growing vacuolated hyphal cells of the high- and the low-penicillin-pro- ducing strains Penicillium chrysogenum was compared using transmission electron microscopy. In the productive cells of the high-yielding strain the endoplasmic reticulum and the polyribosomes with associated peroxisomes are frequently arranged at the periphery of the cytoplasm and around the vacuoles. At the high activity of penicillin G biosynthesis the immuno-label of the cytosolic isopenicillin N synthase is concentrated at the polyribosomes arranged in the
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Wolfe, Saul, Kiyull Yang, and Maged Khalil. "Conformation–activity relationships and the mechanism of action of penicillin." Canadian Journal of Chemistry 66, no. 11 (1988): 2733–50. http://dx.doi.org/10.1139/v88-424.

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Using the MMPEN parameters of Allinger's MMP2(85) force field, a conformational analysis has been performed on four biologically active penicillins; D-ampicillin, L-α-phenoxyethylpenicillin, penicillin G, and penicillin V, and on five biologically inactive or much less active penicillins: L-ampicillin, D-α-phenoxyethylpenicillin, N-methylpenicillin G, 6α-methylpenicillin G, and bisnorpenicillin G. Antibacterial activity is found to be associated with the existence of a global minimum having a compact structure, whose convex face is accessible to a penicillin binding protein (PBP), with the C3-
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Pourreza, Nahid, Mohammad Reza Fat'hi, and Ali Hatami. "Determination of Penicillin G in Milk Samples Using Its Effect on Cloud Point Extraction of Triiodide Ion." Journal of AOAC INTERNATIONAL 97, no. 4 (2014): 1225–29. http://dx.doi.org/10.5740/jaoacint.13-113.

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Abstract A cloud point extraction (CPE) method for determination of trace amounts of penicillin G by spectrophotometry based on its effect on the triiodide ion (I3–) has been developed. Penicillin G is converted to the corresponding penicilloic acid by carrying out hydrolysis with sodium hydroxide solution, and treatment with acid yields D-penicillamine that is oxidized quantitatively by iodine to give rise to a disulfide. The I3– remaining in the solution is extracted into the surfactant Triton X-100, and the difference between absorbance of the working solution in the presence and absence of
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Dissertations / Theses on the topic "Penicillin G Penicillin G"

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Nusche, Marina. "Homöopathie oder Penicillin bei Mandelentzündung? : eine prospektive klinische Studie /." Stuttgart : Hippokrates-Verl, 1998. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=007992367&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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Karhoot, J. M. "Production of penicillin G by Penicillium chrysogenum immobilized in rotating disc fermenters." Thesis, University of Strathclyde, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381320.

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El-Sheikh, Soliman M. "Resistance to sulphonamide and penicillin G in meningococci." Thesis, University of Manchester, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.237470.

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Ariyo, Bolatito Taiwo Onigbogi. "Studies on the effects of oligosaccharides on penicillin G production in cultures of Penicillium chrysogenum." Thesis, University of Westminster, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283468.

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Morillas, Manuel. "Catalytic pathway and conformational stability of penicillin G acylase." Thesis, University of Newcastle Upon Tyne, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360276.

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Loo, Bernard Liat Wen. "Optimization of Recombination Methods and Expanding the Utility of Penicillin G Acylase." Diss., Georgia Institute of Technology, 2007. http://hdl.handle.net/1853/19728.

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Protein engineering can be performed by combinatorial techniques (directed evolution) and data-driven methods using machine-learning algorithms. The main characteristic of directed evolution (DE) is the application of an effective and efficient screen or selection on a diverse mutant library. As it is important to have a diverse mutant library for the success of DE, we compared the performance of DNA-shuffling and recombination PCR on fluorescent proteins using sequence information as well as statistical methods. We found that the diversity of the libraries DNA-shuffling and recombination PCR
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Lloyd, Ruth Marie. "Fungal mycelium from penicillin and G production : an alternative protein source for animal production?" Thesis, University of Newcastle Upon Tyne, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247903.

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Ferreira, Juliana de Souza. "Processo intensificado de hidrolise enzimatica de penicilina G e purificação dos produtos em reator multi-estagio e contra-corrente." [s.n.], 2004. http://repositorio.unicamp.br/jspui/handle/REPOSIP/267674.

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Orientadores: Telma Teixeira Franco, Adrianus Johannes Straanhof, Lucas Antonius Maria van der Wielen<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Quimica<br>Made available in DSpace on 2018-08-05T06:02:03Z (GMT). No. of bitstreams: 1 Ferreira_JulianadeSouza_D.pdf: 5552134 bytes, checksum: f2234304e4f228a88bb1b83073350bfa (MD5) Previous issue date: 2004<br>Resumo: Este trabalho estuda a hidrólise enzimática da penicilina G (PenG) em ácido 6-aminopenicilânico (6-APA) e ácido fenil acético (PAA). Em um reator contra-corrente multi-estágio e em baixos valores
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Silva, Kattya Gyselle de Holanda e. "Nanosistemas de penicilina G benzatina para tratamento profil?tico da febre reum?tica: estudo anal?tico." Universidade Federal do Rio Grande do Norte, 2006. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13432.

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Made available in DSpace on 2014-12-17T14:14:05Z (GMT). No. of bitstreams: 1 KattyaGHS.pdf: 407113 bytes, checksum: 7bf14e459b09e873eacee8a4b0b41b74 (MD5) Previous issue date: 2006-08-17<br>Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior<br>Investigations in the field of pharmaceutical analysis and quality control of medicines require analytical procedures with good perfomance characteristics. Calibration is one of the most important steps in chemical analysis, presenting direct relation to parameters such as linearity. This work consisted in the development of a new methodology
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Rodrigues, Dasciana de Sousa. "Inovações na produção de antibióticos β-lactâmicos." Universidade Federal de São Carlos, 2009. https://repositorio.ufscar.br/handle/ufscar/3862.

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Made available in DSpace on 2016-06-02T19:55:23Z (GMT). No. of bitstreams: 1 2455.pdf: 1413452 bytes, checksum: 0d85e80e19b01ab27cd6e9dd30beb3b9 (MD5) Previous issue date: 2009-04-02<br>Financiadora de Estudos e Projetos<br>The industrial production of 6-APA includes: (1) cultivation of Penicillium chrysogenum; (2) extraction with organic solvents, (3) crystallization; (4) penicillin hydrolysis by immobilized penicillin acylase; (5) extraction of phenyl acetic acid (AFA); (6) precipitation of 6-APA at its isoelectric point ( pH ~ 3,6). The scientific community and industry have interest in r
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Books on the topic "Penicillin G Penicillin G"

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Domingue, Pierre Alain Gilbert. Influence of sub-inhibitory concentrations of penicillin G on surface properties of iron-deprived staphylococcus aureus NCTC 6571. Aston University. Department of Pharmaceutical Sciences, 1986.

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Morgan, Marina. Other bacterial diseasesStreptococcosis. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0023.

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Many pyogenic (β -haemolytic) streptococci of clinical significance have animal connections. In the last edition of this book two species of streptococci were considered of major zoonotic interest, namely Streptococcus suis and S. zooepidemicus. Since then, numerous sporadic zoonoses due to other streptococci have been reported, and a newly recognized fish pathogen with zoonotic potential termed S. iniae has emerged. Changes in nomenclature make the terminology confusing. For example, the organism known as S. zooepidemicus — now termed S. dysgalactiae subsp. zooepidemicus — still causes pharyn
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Tuekam, Brigitte Albertine. Isolation, purification and characterization of Penicillium charlesii G. Smith exo- ø-galactofuranosidase. 1993.

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Book chapters on the topic "Penicillin G Penicillin G"

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van Gulik, W. M., W. A. van Winden та J. J. Heijnen. "Modeling the metabolism of Penicillin-G formation". У Synthesis of β-Lactam Antibiotics. Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-0850-1_7.

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Baldaro, Eva, Claudio Fuganti, Stefano Servi, Auro Tagliani, and Marco Terreni. "The Use of Immobilized Penicillin G Acylase in Organic Synthesis." In Microbial Reagents in Organic Synthesis. Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2444-7_14.

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Mateo, Cesar, Valeria Grazu, Olga Abian, et al. "Preparation of an Industrial Biocatalyst of Penicillin G Acylase on Sepabeads." In Microbial Enzymes and Biotransformations. Humana Press, 2005. http://dx.doi.org/10.1385/1-59259-846-3:273.

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van den Broek, P. J., and R. van Furth. "Influence of monocytes on the antibacterial activity of penicillin G on Staphylococcus aureus." In Mononuclear Phagocytes. Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-5020-7_49.

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Pinotti, Laura M., Rosineide G. Silva, Roberto C. Giordano, and Raquel L. C. Giordano. "Inoculum Studies in Production of Penicillin G Acylase by Bacillus megaterium ATCC 14945." In Biotechnology for Fuels and Chemicals. Humana Press, 2002. http://dx.doi.org/10.1007/978-1-4612-0119-9_55.

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GonçAlves, Luciana R. B., Roberto Fernandez-Lafuente, Jose M. Guisán, and Raquel L. C. Giordano. "A Kinetic Study of Synthesis of Amoxicillin Using Penicillin G Acylase Immobilized on Agarose." In Twenty-First Symposium on Biotechnology for Fuels and Chemicals. Humana Press, 2000. http://dx.doi.org/10.1007/978-1-4612-1392-5_72.

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Pinotti, Laura M., Astrea F. S. Silva, Rosineide G. Silva, and Raquel L. C. Giordano. "Study of Different Media for Production of Penicillin G Acylase from Bacillus megaterium ATCC 14945." In Twenty-First Symposium on Biotechnology for Fuels and Chemicals. Humana Press, 2000. http://dx.doi.org/10.1007/978-1-4612-1392-5_50.

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Bochtler-Hock, H., and Frank Wedekind. "Cell-Free Expression of the Heterodimeric Protein Penicillin G Amidase in a Functionally Active Form." In Cell-Free Protein Expression. Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/978-3-642-59337-6_22.

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Galunsky, Boris, Karsten Lummer, and Volker Kasche. "Comparative Study of Substrate-and Stereospecificity of Penicillin G amidases from Different Sources and Hybrid Isoenzymes." In Biocatalysis. Springer Vienna, 2000. http://dx.doi.org/10.1007/978-3-7091-6310-8_6.

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Martinez-Suárez, J. V., R. Lujan, J. A. Vázquez, et al. "Epidemiological markers of relatively penicillin G-resistant N. meningitidis isolated from patients in Spain (1985-1989)." In Neisseriae 1990, edited by Mark Achtman, Peter Kohl, Christian Marchal, Giovanna Morelli, Andrea Seiler, and Burghard Thiesen. De Gruyter, 1991. http://dx.doi.org/10.1515/9783110867787-020.

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Conference papers on the topic "Penicillin G Penicillin G"

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Smith, David J., S. J. Lupton, Weilin L. Shelver, D. J. Newman, and S. Larsen. "Depletion of penicillin G residues in sows after intramuscular injection." In 10th International Conference on the Epidemiology and Control of Biological, Chemical and Physical Hazards in Pigs and Pork. Iowa State University, Digital Press, 2013. http://dx.doi.org/10.31274/safepork-180809-904.

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Loubna, Nasri. "Modified Equation of State and Sublimation Pressure of Antibiotic Penicillin G." In 2019 10th International Renewable Energy Congress (IREC). IEEE, 2019. http://dx.doi.org/10.1109/irec.2019.8754526.

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Cong Wang, Huacai Chen, and Jianjun Ma. "The fiber-optic evanescent wave fluorescence sensor with a novel sensing architecture for determining penicillin G." In 2011 International Conference on Electronics and Optoelectronics (ICEOE). IEEE, 2011. http://dx.doi.org/10.1109/iceoe.2011.6013287.

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Shelver, Weilin L., S. J. Lupton, D. J. Newman, S. Larsen, and David J. Smith. "Evaluation of penicillin G residues by kidney inhibition swab tests in sow body fluids and tissues following intramuscular injection." In 10th International Conference on the Epidemiology and Control of Biological, Chemical and Physical Hazards in Pigs and Pork. Iowa State University, Digital Press, 2013. http://dx.doi.org/10.31274/safepork-180809-903.

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Shelver, Weilin L., S. J. Lupton, D. J. Newman, S. Larsen, and D. J. Smith. "Evaluation of penicillin G residues by kidney inhibition swab tests in sow body fluids and tissues following intramuscular injection." In 10th International Conference on the Epidemiology and Control of Biological, Chemical and Physical Hazards in Pigs and Pork. Iowa State University, Digital Press, 2013. http://dx.doi.org/10.31274/safepork-180809-943.

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Izquierdo, E., A. Lazaro-Cebas, A. Carreño-Ocaña, et al. "5PSQ-032 Administration protocol for penicillin G in a patient with a severe reaction to betalactams and abdominal actinomycosis." In 24th EAHP Congress, 27th–29th March 2019, Barcelona, Spain. British Medical Journal Publishing Group, 2019. http://dx.doi.org/10.1136/ejhpharm-2019-eahpconf.465.

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Uehara, Kenyu, and Takashi Saito. "Dependency ECoG Band Spectrum in Epileptic Discharges Upon Local Cooling Rate on Brain." In ASME 2017 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/imece2017-72158.

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Focal brain cooling has recently drawn attention as a less-invasive treatment for intractable epileptic patients. The objective of this study is to investigate the dependence of brain cooling rate on epileptic discharges (EDs) suppression with experiments using four epilepsy model rat. EDs were induced by Penicillin G in anesthetized rat, and cooled to 16 °C under four different time conditions (30, 60, 100 and 200 second, respectively). The ECoG obtained from the experiments were sorted into frequency band components which have physiological significance. The results of frequency analyses con
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Buiting, A. G. M., J. Thomson, J. J. Emeis, H. Mattie, E. J. P. Brommer, and R. Van Furth. "EFFECT OF TISSUE-TYPE PLASMINOGEN ACTIVATOR (t-PA) ON BACTERIAL ENDOCARDITIS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643742.

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In bacterial endocarditis the causing microorganisms are located in a fibrin-platelet matrix, making them less accessible to host-defence mechanisms and antibiotic therapy. Trombolytic treatment could break down the fibrin of these endocardial vegetations and thus eliminate the focus of infection. This approach was studied in vitroand in vivo using recombinant t-PA (rt-PA,Wellcome Biotech) having a fibrinolytic activity comparable with melanoma t-PA. The following results were obtained.1.Incubation of Streptococcus sanguis infected plasma clots in the presence of t-PA resulted in lysis of the
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JOVAIŠIENĖ, Jurgita, Bronius BAKUTIS, Violeta BALIUKONIENĖ, Audrius KAČERGIUS, Algimantas PAŠKEVIČIUS, and Gediminas GERULIS. "HYGIENIC SANITARY ESTIMATION OF MAIZE SILAGE IN DAIRY FARMS IN LITHUANIA." In Rural Development 2015. Aleksandras Stulginskis University, 2015. http://dx.doi.org/10.15544/rd.2015.023.

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The aim of this study was to estimate maize silage hygienic sanitary parameters, contamination with mycotoxins in dairy farms in Lithuania. In 2011–2012 maize silage samples were collected from 20 dairy farms: prior to ensiling and 3 and 8 months after ensiling. In maize samples, prior to ensiling, L. monocytogenes was detected 25.0 % and after 3 months of ensiling – 10 %. Average of yeast and filamentous fungi in raw material samples were respectively – 71.39 ± 32.17 and 47.67 ± 18.31 CFU/g, after 3 months – 50.06 ± 16.09 CFU/g and 28.27 ± 13.18, after 8 months – 213.81 ± 55.98 and 215.08 ± 5
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Obeica, Bruna, Caroline Graça Mota Damasceno, Ana Sanches Prazeres, Jacqueline Assumção Silveira Montuori, Marcos Paulo Cardoso Marques, and Walter Palis Ventura. "Manifestações orais da sífilis: a importância de um pré-natal adequado." In 44° Congresso da SGORJ - XXIII Trocando Ideias. Zeppelini Editorial e Comunicação, 2020. http://dx.doi.org/10.5327/jbg-0368-1416-2020130287.

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Introdução: A sífilis é uma infecção sexualmente transmissível que teve aumento de incidência nos últimos anos. É uma doença que apresenta pluralidade dos sintomas, especialmente na fase secundária, e as manifestações orais nesse estágio mais comuns são úlceras ou lesões pseudomembranosas nos lábios inferiores e na língua. A ocorrência dessas lesões está relacionada com prática desprotegida de sexo oral e é um diagnóstico que deve ser considerado naqueles pacientes com úlceras orais atípicas, mesmo na ausência de outros sintomas sistêmicos. Objetivo: Ressaltar a importância de adequado exame f
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