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Dissertations / Theses on the topic 'Penicillin G Penicillin G'

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Published: 4 June 2021

Last updated: 7 February 2022

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1

Nusche, Marina. "Homöopathie oder Penicillin bei Mandelentzündung? : eine prospektive klinische Studie /." Stuttgart : Hippokrates-Verl, 1998. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=007992367&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.

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2

Karhoot, J. M. "Production of penicillin G by Penicillium chrysogenum immobilized in rotating disc fermenters." Thesis, University of Strathclyde, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.381320.

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3

El-Sheikh, Soliman M. "Resistance to sulphonamide and penicillin G in meningococci." Thesis, University of Manchester, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.237470.

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4

Ariyo, Bolatito Taiwo Onigbogi. "Studies on the effects of oligosaccharides on penicillin G production in cultures of Penicillium chrysogenum." Thesis, University of Westminster, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283468.

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5

Morillas, Manuel. "Catalytic pathway and conformational stability of penicillin G acylase." Thesis, University of Newcastle Upon Tyne, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360276.

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6

Loo, Bernard Liat Wen. "Optimization of Recombination Methods and Expanding the Utility of Penicillin G Acylase." Diss., Georgia Institute of Technology, 2007. http://hdl.handle.net/1853/19728.

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Protein engineering can be performed by combinatorial techniques (directed evolution) and data-driven methods using machine-learning algorithms. The main characteristic of directed evolution (DE) is the application of an effective and efficient screen or selection on a diverse mutant library. As it is important to have a diverse mutant library for the success of DE, we compared the performance of DNA-shuffling and recombination PCR on fluorescent proteins using sequence information as well as statistical methods. We found that the diversity of the libraries DNA-shuffling and recombination PCR

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7

Lloyd, Ruth Marie. "Fungal mycelium from penicillin and G production : an alternative protein source for animal production?" Thesis, University of Newcastle Upon Tyne, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.247903.

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8

Ferreira, Juliana de Souza. "Processo intensificado de hidrolise enzimatica de penicilina G e purificação dos produtos em reator multi-estagio e contra-corrente." [s.n.], 2004. http://repositorio.unicamp.br/jspui/handle/REPOSIP/267674.

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Orientadores: Telma Teixeira Franco, Adrianus Johannes Straanhof, Lucas Antonius Maria van der Wielen<br>Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Quimica<br>Made available in DSpace on 2018-08-05T06:02:03Z (GMT). No. of bitstreams: 1 Ferreira_JulianadeSouza_D.pdf: 5552134 bytes, checksum: f2234304e4f228a88bb1b83073350bfa (MD5) Previous issue date: 2004<br>Resumo: Este trabalho estuda a hidrólise enzimática da penicilina G (PenG) em ácido 6-aminopenicilânico (6-APA) e ácido fenil acético (PAA). Em um reator contra-corrente multi-estágio e em baixos valores

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9

Silva, Kattya Gyselle de Holanda e. "Nanosistemas de penicilina G benzatina para tratamento profil?tico da febre reum?tica: estudo anal?tico." Universidade Federal do Rio Grande do Norte, 2006. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13432.

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Made available in DSpace on 2014-12-17T14:14:05Z (GMT). No. of bitstreams: 1 KattyaGHS.pdf: 407113 bytes, checksum: 7bf14e459b09e873eacee8a4b0b41b74 (MD5) Previous issue date: 2006-08-17<br>Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior<br>Investigations in the field of pharmaceutical analysis and quality control of medicines require analytical procedures with good perfomance characteristics. Calibration is one of the most important steps in chemical analysis, presenting direct relation to parameters such as linearity. This work consisted in the development of a new methodology

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10

Rodrigues, Dasciana de Sousa. "Inovações na produção de antibióticos β-lactâmicos." Universidade Federal de São Carlos, 2009. https://repositorio.ufscar.br/handle/ufscar/3862.

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Made available in DSpace on 2016-06-02T19:55:23Z (GMT). No. of bitstreams: 1 2455.pdf: 1413452 bytes, checksum: 0d85e80e19b01ab27cd6e9dd30beb3b9 (MD5) Previous issue date: 2009-04-02<br>Financiadora de Estudos e Projetos<br>The industrial production of 6-APA includes: (1) cultivation of Penicillium chrysogenum; (2) extraction with organic solvents, (3) crystallization; (4) penicillin hydrolysis by immobilized penicillin acylase; (5) extraction of phenyl acetic acid (AFA); (6) precipitation of 6-APA at its isoelectric point ( pH ~ 3,6). The scientific community and industry have interest in r

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11

Weber, Patricia [Verfasser], and Günter [Akademischer Betreuer] Gauglitz. "Optische Sensoren zum Nachweis von Penicillin G in der Prozess- und Umweltanalytik / Patricia Weber ; Betreuer: Günter Gauglitz." Tübingen : Universitätsbibliothek Tübingen, 2018. http://d-nb.info/1196701342/34.

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12

Aguiar, André Andrade de. "Avaliação da microbiota bucal em pacientes sob uso crônico de penicilina G benzatina." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/5/5131/tde-24092009-171538/.

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A Febre Reumática, complicação tardia de uma infecção de orofaringe causada pelo Streptococcus pyogenes (estreptococo -hemolítico do grupo A de Lancefield), tem como conseqüência a Cardiopatia Reumática, explicada pelo mimetismo molecular entre proteínas cardíacas humanas e a associação de proteínas e carboidratos da membrana do S. pyogenes. A profilaxia secundária com a PGB 1.200.000 UI IM propõe-se a evitar novos surtos, sendo administrada em intervalos de vinte e um dias nos países com alto índice de estreptococcia. A lesão valvar predispõe à Endocardite Infecciosa, que resulta de bacteriem

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13

Lima, Vanessa Morais. "Efeitos da penicilina G na pelve renal de ratos Wistar (Rattus norvegicus albinus) normais e diabéticos." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/10/10132/tde-09102013-180434/.

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A penicilina G é um dos antibióticos mais importantes. Além de possuir um baixo preço e comprovada eficácia de tratamento, mostra inúmeras possibilidades para a redução da morbidade e mortalidade por doenças infecciosas em todo o mundo. Como eventualmente este medicamento causa sequelas no parênquima renal e estruturas associadas, e sendo que a secreção da rede tubular renal contribui para a excreção da penicilina G, onde cerca de 60% do antibiótico é eliminado pela urina, nos propomos a fazer um estudo das principais alterações que possam ocorrer na pelve renal de ratos normais e ratos induzi

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14

Murchie, Tracy Ann. "Measuring gentamicin and penicillin concentrations in allantoic fluid of pregnant pony mares by in vivo microdialysis." [Gainesville, Fla.] : University of Florida, 2004. http://purl.fcla.edu/fcla/etd/UFE0004906.

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Thesis (M.S.)--University of Florida, 2004.<br>Typescript. Title from title page of source document. Document formatted into pages; contains 152 pages. Includes Vita. Includes bibliographical references.

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15

Domingue, Pierre A. G. "Influence of sub-inhibitory concentrations of penicillin G on surface properties of iron-deprived staphylococcus aureus NCTC 6571." Thesis, Aston University, 1986. http://publications.aston.ac.uk/12466/.

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16

Scherrer, Serge. "Étude sur la maturation protéolytique du précurseur de la pénicilline g amidase d'Escherichia coli : compétition entre maturation et agrégation in vivo : repliement et maturation du précurseur in vitro : effet de mutations dans le gène sur la maturation." Nancy 1, 1994. http://www.theses.fr/1994NAN10408.

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La pénicilline g amidase (pga) d'e. Coli atcc 11105 est une enzyme de haut intérêt industriel, utilisée pour la production des antibiotiques de type b-lactame. Les pga bactériennes ont la particularité d'être des hétérodimères, produits par une double protéolyse interne d'un précurseur protéique. L'utilisation au niveau industriel de la surproduction de pga par bactéries recombinées semble limitée par l'existence de ce processus de maturation. J'ai employé différentes approches pour essayer d'apporter des informations sur ce processus. Par une étude in vivo, j'ai montré que la surproduction du

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17

Pereira, Sandra Cerqueira. "Inovações na síntese enzimática de amoxicilina." Universidade Federal de São Carlos, 2012. https://repositorio.ufscar.br/handle/ufscar/3917.

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Made available in DSpace on 2016-06-02T19:55:33Z (GMT). No. of bitstreams: 1 4561.pdf: 2229870 bytes, checksum: e51008e96773b0184eb28a316cf86d57 (MD5) Previous issue date: 2012-04-27<br>Financiadora de Estudos e Projetos<br>Penicillin G acylase (PGA, E.C.3.5.1.11) from Escherichia coli is an enzyme of great industrial importance, widely used for the hydrolysis of penicillin G, producing the 6-aminopenicillanic acid (6-APA), which is a key molecule for the synthesis of semi-synthetic penicillins. Among them, amoxicillin has a broad spectrum of activity against a variety of bacteriological inf

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18

Mayer, Janine Verfasser], Dieter [Akademischer Betreuer] [Jahn, and Anett [Akademischer Betreuer] Schallmey. "Struktur-basiertes Protein Engineering von neuen Penicillin G Acylasen aus Gram-positiven Bakterien für innovative biotechnologische Anwendungen / Janine Mayer ; Dieter Jahn, Anett Schallmey." Braunschweig : Technische Universität Braunschweig, 2021. http://d-nb.info/1228533776/34.

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19

Ambay, Taddese Mekonnen [Verfasser], Werner [Akademischer Betreuer] Weitschies, Werner [Gutachter] Weitschies, and Henning [Gutachter] Blume. "Development of Formulations of Penicillin G for the Local Treatment of Helicobacter pylori / Taddese Mekonnen Ambay ; Gutachter: Werner Weitschies, Henning Blume ; Betreuer: Werner Weitschies." Greifswald : Universität Greifswald, 2020. http://d-nb.info/1205879978/34.

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20

Ambay, Taddese Mekonnen [Verfasser], Werner [Akademischer Betreuer] Weitschies, Werner Gutachter] Weitschies, and Henning [Gutachter] [Blume. "Development of Formulations of Penicillin G for the Local Treatment of Helicobacter pylori / Taddese Mekonnen Ambay ; Gutachter: Werner Weitschies, Henning Blume ; Betreuer: Werner Weitschies." Greifswald : Universität Greifswald, 2020. http://d-nb.info/1205879978/34.

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21

Deaguero, Andria Lynn. "Improving the enzymatic synthesis of semi-synthetic beta-lactam antibiotics via reaction engineering and data-driven protein engineering." Diss., Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/42727.

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Semi-synthetic β-lactam antibiotics are the most prescribed class of antibiotics in the world. Chemical coupling of a β-lactam moiety with an acyl side chain has dominated the industrial production of semi-synthetic β-lactam antibiotics since their discovery in the early 1960s. Enzymatic coupling of a β-lactam moiety with an acyl side chain can be accomplished in a process that is much more environmentally benign but also results in a much lower yield. The goal of the research presented in this dissertation is to improve the enzymatic synthesis of β-lactam antibiotics via reaction engineeri

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22

Hünerbein, Ingrid [Verfasser], R. [Akademischer Betreuer] Neubert, W. C. [Akademischer Betreuer] Marsch, and C. S. [Akademischer Betreuer] Leopold. "Untersuchung toxikologischer Effekte von Penicillin G auf das initiale Lymphgefäßsystem und auf die Epithelregeneration der humanen Haut / Ingrid Hünerbein. Betreuer: R. Neubert ; W. C. Marsch ; C. S. Leopold." Halle, Saale : Universitäts- und Landesbibliothek Sachsen-Anhalt, 2010. http://d-nb.info/102501099X/34.

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23

Montaño, Inti Doraci Cavalcanti. "Otimização dinâmica do cultivo semi-contínuo de Pichia pastoris recombinante para produção das enzimas heterólogas alfa amilase e penicilina G acilase." Universidade Federal de São Carlos, 2010. https://repositorio.ufscar.br/handle/ufscar/4051.

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Made available in DSpace on 2016-06-02T19:56:40Z (GMT). No. of bitstreams: 1 3187.pdf: 3659896 bytes, checksum: 975ac91a3eb67a4347c326de8f22bf8e (MD5) Previous issue date: 2010-03-31<br>Universidade Federal de Minas Gerais<br>This master's thesis project aims at studying the dynamic optimization of the operation of a bench scale (up to 5L) automated, agitated and aerated bioreactor, where the semi-continuous cultivation of recombinant Pichia pastoris is run. This yeast was cloned using the PGK1 promoter, which precludes the use of methanol as inducer, expressing constitutively the enzyme pen

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24

Kopp, Willian. "Síntese e ativação superficial de novos suportes magnéticos para imobilização de enzimas." Universidade Federal de São Carlos, 2013. https://repositorio.ufscar.br/handle/ufscar/266.

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Made available in DSpace on 2016-06-02T19:02:43Z (GMT). No. of bitstreams: 1 5706.pdf: 7869131 bytes, checksum: 3a35e736b3418ca357ef4fc2e657c0af (MD5) Previous issue date: 2013-10-16<br>Universidade Federal de Minas Gerais<br>Enzymes are potent catalysts, but operationally fragile, expensive and soluble. Industrial applications of enzymes, often, are possible only using immobilized enzyme. Nowadays, various studies have been performed aiming to immobilize enzymes onto magnetic carriers, which allow the selective recovery of the derivative by applying an external magnetic field even in comple

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25

Nhim, Cathy. "Identification de lymphocytes T spécifiques des médicaments chez des individus non allergiques." Phd thesis, Université Paris Sud - Paris XI, 2012. http://tel.archives-ouvertes.fr/tel-00769921.

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Chez des patients allergiques, il est possible de retrouver dans leur sérum desanticorps spécifiques du médicament (IgE) et dans leur sang des lymphocytes T spécifiquesdu médicament. La présence de LT spécifiques du médicament chez des patients allergiquessuggère la présentation du médicament par des cellules présentatrices d'antigène telles queles cellules dendritiques.Nous nous sommes alors intéressés à mieux comprendre l'implication deslymphocytes T et des cellules dendritiques dans le développement des allergies auxantibiotiques comme la pénicilline G (ou Benzyl-Pénicilline) ou le sulfamét

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26

Pinotti, Laura Marina. "Produção e purificação de penicilina G acilase." Universidade Federal de São Carlos, 2003. https://repositorio.ufscar.br/handle/ufscar/3890.

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Made available in DSpace on 2016-06-02T19:55:28Z (GMT). No. of bitstreams: 1 DoutLMP.pdf: 2279571 bytes, checksum: 007958befffa499c1eb6c72cc2b515c8 (MD5) Previous issue date: 2003-06-26<br>Universidade Federal de Minas Gerais<br>The main objective of the present work was the study of PGA of B. megaterium production process and purification. The following production aspects were investigated in flasks and/or fermenter: the study of the purity of the culture, the standardization and the conservation of the inoculum, the optimization of the total time of cultivation (germination/propagation and

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27

DEBOUDT, ANNE. "Cinquante annees d'utilisation de la penicilline g : passe, present, futur." Lille 2, 1992. http://www.theses.fr/1992LIL2M077.

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28

SOLIVERES, JEAN-MICHEL. "Comparaison des performances de quatre methodes de determination de la resistance aux beta-lactamines chez streptococcus pneumoniae." Lyon 1, 1993. http://www.theses.fr/1993LYO1M069.

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29

GAYON, ANTOINE. "Aspects epidemiologiques et sensibilite aux antibiotiques des pneumocoques isoles pendant une periode de sept mois chez l'adulte, du 1er septembre 1990 au 31 mars 1991 au centre hospitalo-universitaire de purpan-toulouse." Toulouse 3, 1992. http://www.theses.fr/1992TOU31701.

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30

Escallón, Ana María Vélez. "Produção de penicilina G acilase por organismos geneticamente modificados." Universidade Federal de São Carlos, 2013. https://repositorio.ufscar.br/handle/ufscar/3942.

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Made available in DSpace on 2016-06-02T19:55:38Z (GMT). No. of bitstreams: 1 5647.pdf: 2822412 bytes, checksum: 769ca8edf54438ee75a0a4df886371c3 (MD5) Previous issue date: 2013-09-17<br>Universidade Federal de Minas Gerais<br>Penicillin G acilase (PGA) is a key enzyme in the industrial production of β-lactamic antibiotics. In this work, it was studied the production of PGA from Escherichia coli by recombinant E. coli and from Bacillus megaterium by recombinant B. megaterium. In E. coli, the enzyme accumulates in the periplasmic cell space, B. megaterium secretes PGA, what may reduce dow

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31

Barros, André Nogueira Castro de. "Purificação de penicilina G por adsorção em resinas hidrofóbicas." Universidade Federal de São Carlos, 2008. https://repositorio.ufscar.br/handle/ufscar/4018.

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Made available in DSpace on 2016-06-02T19:56:34Z (GMT). No. of bitstreams: 1 2238.pdf: 2195036 bytes, checksum: 24016f830d2199e2b7ce80a59677423d (MD5) Previous issue date: 2008-08-06<br>Universidade Federal de Minas Gerais<br>The separation of biotechnological products is an area of great economic importance once it represents the majority of the cost of this product. On industrial production of penicillin G (penG), the separation of the antibiotic has been made by extraction on organic solvent. However the decrease on the use of these solvents has become imperative in many chemical processe

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32

Miranda, Maria do Carmo de Castro. "Reacoes adversas nao alergicas a suspensao injetavel de benzilpenicilina benzatina: uma revisao sistematica." Rio de Janeiro : [s.n.], 2002. http://teses.cict.fiocruz.br/pdf/mirandamccm.pdf.

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Miranda, Maria do Carmo de Castro. "Reações adversas não alérgicas à suspensão injetável de benzilpenicilina benzatina: uma revisão sistemática." reponame:Repositório Institucional da FIOCRUZ, 2002. https://www.arca.fiocruz.br/handle/icict/4785.

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Made available in DSpace on 2012-09-06T01:11:20Z (GMT). No. of bitstreams: 2 license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) 522.pdf: 2527903 bytes, checksum: 74f52e46e6eee5745cc025ae8acd28aa (MD5) Previous issue date: 2002<br>A benzilpenicilina benzatina é o antibiótico de eleição para algumas doenças graves, que atingem principalmente as populações carentes, como é o caso da febre reumática e da sífilis. O Instituto Nacional de Controle de Qualidade em Saúde (INCQS) recebeu, entre 1990 e 1998 solicitações de análise de produtos contendo benzilpenicilina benzatina

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34

Robas, Nathalie. "Etude de la regulation de l'expression du gene de la penicilline g amidase d'escherichia coli, dans differentes souches productrices et bacteries recombinees : repercussion de la presence d'un plasmide multicopie dans une bacterie." Nancy 1, 1992. http://www.theses.fr/1992NAN12082.

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35

Silva, Kattya Gyselle de Holanda. "Mise au point et développement des systèmes lipidiques émulsionnés contenant la benzathine penicilline G." Paris 11, 2010. http://www.theses.fr/2010PA114859.

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Le rhumatisme articulaire aigu (RAA) est une maladie inflammatoire résultant des infections causées par streptocoques b-hémolytique du groupe A. Un schéma thérapeutique basé sur des injections mensuelles de 1,2 million d'unités internationales de la pénicilline G benzathine (PenGB) a le succès limité dû à plusieurs facteurs dejà connu. La nanothérapie propose des systèmes capables d’amener des médicaments spécifiquement dans les tissus affectés, garantissant une stabilité suffisante, une meilleure absorption, à libération contrôlée et par conséquent l'activité pharmacologique attendu. Parmi ce

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Oguri, Renata Tieko. "Estudo de condições operacionais na produção de penicilina G acilase por diferentes microrganismos." Universidade Federal de São Carlos, 2006. https://repositorio.ufscar.br/handle/ufscar/3989.

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Made available in DSpace on 2016-06-02T19:56:30Z (GMT). No. of bitstreams: 1 DissRTO.pdf: 1502599 bytes, checksum: 74b4b7145b86c0fed8e0b1327b8aaea1 (MD5) Previous issue date: 2006-12-20<br>Universidade Federal de Sao Carlos<br>Penicillin G acylase (PGA) is an enzyme of major impact in human health for catalyzing the deacilation of the penicillin G, to yield 6-aminopenicillanic acid (6- APA), key intermediate in the semi-synthetic antibiotics production. Several microorganisms produce PGA, but Bacillus megaterium is capable of secreting it to the medium. PGA from B. megaterium has been studie

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Altarugio, Lucas Miguel. "Purificação de penicilina G acilase produzida por Escherichia coli e Bacillus megaterium recombinantes." Universidade Federal de São Carlos, 2014. https://repositorio.ufscar.br/handle/ufscar/4140.

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Made available in DSpace on 2016-06-02T19:56:54Z (GMT). No. of bitstreams: 1 6022.pdf: 1662458 bytes, checksum: 4e6f5f48dc72f84e96a68be96f5ddf02 (MD5) Previous issue date: 2014-03-28<br>Financiadora de Estudos e Projetos<br>Penicillin G acylase (PGA) is the key enzyme for the industrial production of β-lactam antibiotics. Major current PGA demand is attended for producer organisms as Escherichia coli and Bacillus megaterium genetically modified. The enzyme produced by Escherichia coli accumulates in the periplasmic space of the bacteria and it requires cell disruption for recovery, wher

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Fernandes, Pedro Luiz. "Inteligência computacional aplicada à automação de biorreator para produção de Penicilina G Acilase (PGA)." Universidade Federal de São Carlos, 2008. https://repositorio.ufscar.br/handle/ufscar/6944.

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Made available in DSpace on 2016-08-17T18:39:29Z (GMT). No. of bitstreams: 1 1987.pdf: 5261399 bytes, checksum: 920886ee9cea1dbc89f0650419ab17e9 (MD5) Previous issue date: 2008-07-11<br>Financiadora de Estudos e Projetos<br>Biotechnology has presented, in the last years, a rapidly growing development. New biotechnological industrial processes are constantly introduced using different microorganisms and/or enzymes. In this context, the application of process control and optimization techniques has become a need for biotechnological based industry. A technological approach was developed in thi

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39

Nucci, Edson Romano. "Aplicação da lógica fuzzi na produção de penicilina G Acilase em cultivos de Bacillus megaterium." Universidade Federal de São Carlos, 2003. https://repositorio.ufscar.br/handle/ufscar/4052.

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Made available in DSpace on 2016-06-02T19:56:40Z (GMT). No. of bitstreams: 1 DissERN.pdf: 1095577 bytes, checksum: db0cd04a8651aaa02aaf07151f39e8e4 (MD5) Previous issue date: 2003-07-28<br>Universidade Federal de Sao Carlos<br>Penicillin G acylase (PGA) is an important enzyme for the pharmaceutical industry. This enzyme has industrial use in the hydrolysis of penicillin G to obtain 6-aminocephalosporanic acid (6-APA), essential intermediate for the production of beta-lactam antibiotics. Many microorganisms produce PGA, but Bacillus megaterium is one of the few that excretes the enzyme to the

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40

Souza, Vanessa Ribeiro de. "Diferentes meios de cultivo e condições operacionais na produção de penicilina G acilase por Bacillus megaterium." Universidade Federal de São Carlos, 2007. https://repositorio.ufscar.br/handle/ufscar/3854.

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Made available in DSpace on 2016-06-02T19:55:21Z (GMT). No. of bitstreams: 1 TeseVRS.pdf: 5281242 bytes, checksum: 8ae3e0f5731bedd5705926ff0020de41 (MD5) Previous issue date: 2007-08-16<br>Universidade Federal de Sao Carlos<br>Penicillin G acylase (PGA) is an important enzyme for industry, used to produce aminopenicillanic acid, a key intermediate in the synthesis of ampicillin, among other betalatam antibiotics. The production of this enzyme by Bacillus megaterium has been studied by the research group for several years. This work advances this research, aiming not only at the enhancement o

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Silva, Rosineide Gomes da. "Inferência de variáveis do processo de produção de penicilina G acilase por Bacillus megaterium ATCC-14945." Universidade Federal de São Carlos, 2003. https://repositorio.ufscar.br/handle/ufscar/3893.

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Made available in DSpace on 2016-06-02T19:55:28Z (GMT). No. of bitstreams: 1 DoutRGS.pdf: 2966707 bytes, checksum: 76003e0d6d999794b955bb26e523ff71 (MD5) Previous issue date: 2003-07-27<br>Universidade Federal de Minas Gerais<br>The enzyme penicillin G acylase (E.C.3.5.1.11) is used in the production of 6-aminopenicillanic acid (6-APA) and 7-aminocephalosporinic acid (7-ACA), which are key intermediates for the production of β-lactam antibiotics. Its industrial importance was one of the motivations for this thesis. On-line measurement and monitoring of cultivations of Bacillus megateriu

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Beck, Isabel L. "Tolérance à la pénicilline G de souches de "Streptococcus pyogenes" isolées au cours d'angines aigue͏̈s de l'enfant." Paris 5, 1993. http://www.theses.fr/1993PA05P199.

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Leite, Geísa de Abreu. "Síntese enzimática de ampicilina com diferentes substratos em reator integrado." Universidade Federal de São Carlos, 2008. https://repositorio.ufscar.br/handle/ufscar/3875.

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Made available in DSpace on 2016-06-02T19:55:25Z (GMT). No. of bitstreams: 1 2414.pdf: 14993428 bytes, checksum: da8b438d6672bb118531117cfa66edcb (MD5) Previous issue date: 2008-12-12<br>Universidade Federal de Sao Carlos<br>Penicillin G acylase (PGA), EC 3.5.1.1.11, is an enzyme employed in the hydrolysis reactions of penicillin G to produce 6-amino penicillanic acid (6-APA), but it can also used in the synthesis of semi-synthetic antibiotics. This work investigated the influence of different biocatalysts conceptions and of different acyl donors on the ampicillin synthesis with immobilized

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Tonin, Fábio Cristiano. "Avaliação de variáveis operacionais e aplicação de enfoque híbrido na modelagem do processo de produção de penicilina G acilase por Bacillus megaterium." Universidade Federal de São Carlos, 2005. https://repositorio.ufscar.br/handle/ufscar/4176.

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Made available in DSpace on 2016-06-02T19:57:00Z (GMT). No. of bitstreams: 1 DissFCT.pdf: 1275381 bytes, checksum: 37915954a1c8462e3ded3fb6eff3f70b (MD5) Previous issue date: 2005-09-08<br>Universidade Federal de Minas Gerais<br>In the present work it was studied the influence of operational conditions particularly dissolved oxygen concentration in the penicillin G acylase (PGA) production. The experiments were carried out in aerated and agitated bioreactor employing bacteria Bacillus megaterium. The production of PGA is sensitive to dissolved oxygen concentration during its cultivation. As

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Suárez, Carlos Alberto Galeano. "Otimização do cultivo de Bacillus megaterium recombinante em bateladas alimentadas." Universidade Federal de São Carlos, 2010. https://repositorio.ufscar.br/handle/ufscar/4050.

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Made available in DSpace on 2016-06-02T19:56:40Z (GMT). No. of bitstreams: 1 3185.pdf: 3522652 bytes, checksum: 063df10d4f80507d55f3980b84be9243 (MD5) Previous issue date: 2010-03-31<br>Universidade Federal de Sao Carlos<br>Penicillin Acylases are enzymes of great industrial importance, being used mainly for production of 6-aminopenicillanic acid, 6-APA from penicillin G. In the late 90's, its use for synthesis of β-lactam semisynthetic antibiotics began on an industrial scale, an alternative in the context of "green chemistry" to the chemical synthesis of high environmental impact. The

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Graciano, Fernando Felipe. "Por que os pacientes não seguem adequadamente as orientações Médicas? Estudo dos fatores envolvidos com a má-adesão à profilaxia secundária da febre reumática com a penicilina-G-benzatina." Universidade Federal de Minas Gerais, 2007. http://hdl.handle.net/1843/ECJS-73AHWD.

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INTRODUCTION: The irregular secondary prophylaxis can determine a worst prognosis of the rheumatic fever.There are few objectives studies that have been dedicated to establish the secondary prophylaxis possible risk factors.OBJECTIVES: To analyze possible factors involved with poor compliance to secondary prophylaxis of rheumatic fever SETTING: Universidade Federal de Minas Gerais, Brazil. STUDY DESIGN: Crosssectional. PATIENTS: A total of 189 patients followed-up in a rheumatic fever outpatient clinic answered a standardized questionnaire, and their injection control cards and medical charts

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Mcvey, Colin Edward. "Substrate specificity of penicillin G acylase." Doctoral thesis, 1999. http://hdl.handle.net/10362/50167.

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Huseman, Brian Roy. "Determination of the magnitude and duration of penicillin serum levels in swine following a single intramuscular injection of procaine penicillin G and benzathine penicillin G." 1986. http://hdl.handle.net/2097/22086.

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Cheng, Wen-Ming, and 鄭文明. "The Optimization Problems of Penicillin G Fermentation Process." Thesis, 1997. http://ndltd.ncl.edu.tw/handle/48966086942137605989.

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碩士<br>國立中正大學<br>化學工程研究所<br>85<br>Antibiotic is an important medicine that plays an essential role in pharmaceutical market . Penicillin G is one kind of up stream materials for developing various antibiotics , for which much attention has recently been focused on how to produce a large quantity of Penicillin G in demand . At present , Penicillin G production often uses batch or fed-batch fermentation by molds , the fermentation process needs further impr

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Baumert, Josef. "Untersuchungen zur Optimierung der Penicillin-G-Acylase Produktion /." 1995. http://www.gbv.de/dms/bs/toc/198126239.pdf.

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