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Journal articles on the topic 'Penicillium rubens'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Lalchhandama, Kholhring. "History of penicillin." WikiJournal of Medicine 8, no. 1 (2021): 3. http://dx.doi.org/10.15347/wjm/2021.003.

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The history of penicillin was shaped by the contributions of numerous scientists. The ultimate result was the discovery of the mould Penicillium's antibacterial activity and the subsequent development of penicillins, the most widely used antibiotics. Following an accidental discovery of the mould, later identified as Penicillium rubens, as the source of the antibacterial principle (1928) and the production of a pure compound (1942), penicillin became the first naturally derived antibiotic. There is anecdotal evidence of ancient societies using moulds to treat infections and of awareness that v

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Sawant, Amol M., Vishwambar D. Navale, and Koteswara Rao Vamkudoth. "Isolation and Molecular Characterization of Indigenous Penicillium chrysogenum/rubens Strain Portfolio for Penicillin V Production." Microorganisms 11, no. 5 (2023): 1132. http://dx.doi.org/10.3390/microorganisms11051132.

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Beta (β)-lactam antibiotic is an industrially important molecule produced by Penicillium chrysogenum/rubens. Penicillin is a building block for 6-aminopenicillanic acid (6-APA), an important active pharmaceutical intermediate (API) used for semi-synthetic antibiotics biosynthesis. In this investigation, we isolated and identified Penicillium chrysogenum, P. rubens, P. brocae, P. citrinum, Aspergillus fumigatus, A. sydowii, Talaromyces tratensis, Scopulariopsis brevicaulis, P. oxalicum, and P. dipodomyicola using the internal transcribed spacer (ITS) region and the β-tubulin (BenA) gene for pre

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Gil-Durán, Carlos, Diego Palma, Yudethzi Marcano, et al. "CRISPR/Cas9-Mediated Disruption of the pcz1 Gene and Its Impact on Growth, Development, and Penicillin Production in Penicillium rubens." Journal of Fungi 9, no. 10 (2023): 1010. http://dx.doi.org/10.3390/jof9101010.

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Penicillium rubens is a filamentous fungus of great biotechnological importance due to its role as an industrial producer of the antibiotic penicillin. However, despite its significance, our understanding of the regulatory mechanisms governing biological processes in this fungus is still limited. In fungi, zinc finger proteins containing a Zn(II)2Cys6 domain are particularly interesting regulators. Although the P. rubens genome harbors many genes encoding proteins with this domain, only two of them have been investigated thus far. In this study, we employed CRISPR-Cas9 technology to disrupt th

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Boruta, Tomasz, Anna Ścigaczewska, and Marcin Bizukojć. "Investigating the Stirred Tank Bioreactor Co-Cultures of the Secondary Metabolite Producers Streptomyces noursei and Penicillium rubens." Biomolecules 13, no. 12 (2023): 1748. http://dx.doi.org/10.3390/biom13121748.

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The stirred tank bioreactor co-cultures of the filamentous fungus Penicillium rubens and actinomycete Streptomyces noursei were studied with regard to secondary metabolite (SM) production, sugar consumption, and dissolved oxygen levels. In addition to the quantitative analysis of penicillin G and nystatin A1, the broad repertoire of 22 putatively identified products was semi-quantitatively evaluated with the use of UPLC-MS. Three co-cultivation variants differing with respect to the co-culture initiation method (i.e., the simultaneous inoculation of P. rubens and S. noursei and the 24 or 48 h

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Boruta, Tomasz, Anna Ścigaczewska, Agnieszka Ruda, and Marcin Bizukojć. "Effects of the Coculture Initiation Method on the Production of Secondary Metabolites in Bioreactor Cocultures of Penicillium rubens and Streptomyces rimosus." Molecules 28, no. 16 (2023): 6044. http://dx.doi.org/10.3390/molecules28166044.

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Bioreactor cocultures involving Penicillium rubens and Streptomyces rimosus were investigated with regard to secondary metabolite production, morphological development, dissolved oxygen levels, and carbon substrate utilization. The production profiles of 22 secondary metabolites were analyzed, including penicillin G and oxytetracycline. Three inoculation approaches were tested, i.e., the simultaneous inoculation of P. rubens with S. rimosus and the inoculation of S. rimosus delayed by 24 or 48 h relative to P. rubens. The delayed inoculation of S. rimosus into the P. rubens culture did not pre

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Houbraken, Jos, Jens C. Frisvad, and Robert A. Samson. "Fleming’s penicillin producing strain is not Penicillium chrysogenum but P. rubens." IMA Fungus 2, no. 1 (2011): 87–95. http://dx.doi.org/10.5598/imafungus.2011.02.01.12.

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7

Campos, C., T. G. Lázaro-Rodríguez, E. Hernández-Pérez, R. Rincón-Heredia, and F. J. Fernández. "Pexophagy modes during penicillin biosynthesis in Penicillium rubens P2-32-T." Archives of Microbiology 202, no. 8 (2020): 2337–41. http://dx.doi.org/10.1007/s00203-020-01939-3.

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8

García-Calvo, Laura, Raquel Rodríguez-Castro, Ricardo V. Ullán, et al. "Penicillium chrysogenum as a fungal factory of feruloyl esterases." Applied Microbiology and Biotechnology 107 (December 8, 2022): 691–717. https://doi.org/10.1007/s00253-022-12335-w.

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AbstractPlant biomass is a promising substrate for biorefinery, as well as a source of bioactive compounds, platform chemicals, andprecursors with multiple industrial applications. These applications depend on the hydrolysis of its recalcitrant structure.However, the effective biological degradation of plant cell walls requires several enzymatic groups acting synergistically,and novel enzymes are needed in order to achieve profitable industrial hydrolysis processes. In the present work, a feruloylesterase (FAE) activity screening of <em>Penicillium </em>spp. strains revealed a promising candid

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Hupka, Megan, Raj Kedia, Rylee Schauer, et al. "Morphology of Penicillium rubens Biofilms Formed in Space." Life 13, no. 4 (2023): 1001. http://dx.doi.org/10.3390/life13041001.

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Fungi biofilms have been found growing on spacecraft surfaces such as windows, piping, cables, etc. The contamination of these surfaces with fungi, although undesirable, is highly difficult to avoid. While several biofilm forming species, including Penicillium rubens, have been identified in spacecraft, the effect of microgravity on fungal biofilm formation is unknown. This study sent seven material surfaces (Stainless Steel 316, Aluminum Alloy, Titanium Alloy, Carbon Fiber, Quartz, Silicone, and Nanograss) inoculated with spores of P. rubens to the International Space Station and allowed biof

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Kisová, Zuzana, Andrea Šoltýsová, Mária Bučková, Gábor Beke, Andrea Puškárová, and Domenico Pangallo. "Studying the Gene Expression of Penicillium rubens Under the Effect of Eight Essential Oils." Antibiotics 9, no. 6 (2020): 343. http://dx.doi.org/10.3390/antibiotics9060343.

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Essential oils (EOs) are well-known for their beneficial properties against a broad range of microorganisms. For the better understanding of their mechanism of action in fungi, a microarray approach was used in order to evaluate the gene expression of Penicillium chrysogenum (recently renamed P. rubens) exposed to the indirect contact (vapors) of eight EOs. The selection of assayed EOs was based on their antifungal activity. The extraction of RNA and the microarray hybridization procedure were optimized for the analysis of P. rubens. Gene ontology annotation was performed to investigate the fu

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Campos, C., T. G. Lázaro-Rodríguez, R. Fragoso-Soriano, and F. J. Fernández. "Vesicular transport and secretion of penicillin G in Penicillium rubens P2-32-T." Archives of Microbiology 202, no. 5 (2020): 1257–62. http://dx.doi.org/10.1007/s00203-019-01806-w.

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Ruijten, Philip, Hendrik P. Huinink, and Olaf C. G. Adan. "Hyphal growth of Penicillium rubens in changing relative humidity." Applied Microbiology and Biotechnology 105, no. 12 (2021): 5159–71. http://dx.doi.org/10.1007/s00253-021-11343-6.

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Abstract When considering mold prevention strategies, the environmental conditions in which fungi grow need to be taken into consideration. This environment is often characterized by a time-dependent relative humidity, and porous substrate. Growth has mainly been investigated in steady-state experiments. Therefore, the goal of this study is to understand the hyphal growth of Penicillium rubens on porous gypsum, under dynamic humidity conditions. Spores of P. rubens were inoculated on porous gypsum containing nutrients, and placed in a small incubation chamber, allowing for microscopic hyphal o

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Espeso, E. A., M. Villarino, M. Carreras, et al. "Altered nitrogen metabolism in biocontrol strains of Penicillium rubens." Fungal Genetics and Biology 132 (November 2019): 103263. http://dx.doi.org/10.1016/j.fgb.2019.103263.

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Xu, Xiuli, Yifei Dong, Jinpeng Yang, et al. "Secondary Metabolites from Marine-Derived Fungus Penicillium rubens BTBU20213035." Journal of Fungi 10, no. 6 (2024): 424. http://dx.doi.org/10.3390/jof10060424.

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Two new polyketide derivatives, penirubenones A and B (1 and 2), and two naturally rare amino-bis-tetrahydrofuran derivatives, penirubenamides A and B (3 and 4), together with nine known compounds (5–13) were isolated from the marine-derived fungus Penicillium rubens BTBU20213035. The structures were identified by HRESIMS and 1D and 2D NMR analyses, and their absolute configurations were determined by a comparison of experimental and calculated electronic circular dichroism (ECD) spectroscopy and 13C NMR data. We found that 6 exhibited antibacterial activity against Staphylococcus aureus, with

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Ortellado, Laura Ester, Alan Rolando Ayala Schimpf, Silvana Florencia Benítez, Laura Lidia Villalba, Pedro Darío Zapata, and María Isabel Fonseca. "Sustainable Bioremediation of Lipid-Rich Wastewater Using a Lipase from Penicillium rubens LBM 081." Water 17, no. 10 (2025): 1509. https://doi.org/10.3390/w17101509.

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The improper discharge of wastewater has increased the presence of pollutants, among which lipids are particularly problematic. These compounds form oily layers that hinder oxygen transfer and sunlight penetration, negatively impacting aquatic ecosystems. Conventional methods for treating such effluents are often costly and environmentally unfriendly. In this context, bioremediation using lipases, such as those produced by Penicillium rubens LBM 081, represents an effective and sustainable alternative. This study evaluated the biotechnological potential of the lipase from P. rubens LBM 081 for

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Fierro, Francisco, Inmaculada Vaca, Nancy I. Castillo, Ramón Ovidio García-Rico, and Renato Chávez. "Penicillium chrysogenum, a Vintage Model with a Cutting-Edge Profile in Biotechnology." Microorganisms 10, no. 3 (2022): 573. http://dx.doi.org/10.3390/microorganisms10030573.

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The discovery of penicillin entailed a decisive breakthrough in medicine. No other medical advance has ever had the same impact in the clinical practise. The fungus Penicillium chrysogenum (reclassified as P. rubens) has been used for industrial production of penicillin ever since the forties of the past century; industrial biotechnology developed hand in hand with it, and currently P. chrysogenum is a thoroughly studied model for secondary metabolite production and regulation. In addition to its role as penicillin producer, recent synthetic biology advances have put P. chrysogenum on the path

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Baiotto, Cristiano Sartori, Luana Maria Corrêa Baiotto, Simony Costa Beber, et al. "Antifungal activity of essential oils of Rosmarinus officinalis and Corymbia citriodora in the control of Aspergillus flavus and Penicillium rubens." Cadernos Cajuína 10, no. 1 (2025): e971. https://doi.org/10.52641/cadcajv10i1.971.

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The objective was to evaluate the in vitro fungicidal effect of essential oils of rosemary (Rosmarinus officinalis Linn. - Lamiaceae), eucalyptus (Corymbia citriodora (Hook.) Hill & Johnson - Myrtaceae) on the fungi Aspergillus flavus and Penicillium rubens. This is an experimental study, in vitro. As a result, it was observed that the essential oil of C. citriodora at a concentration of 1000 µL mL-1 was more effective than the others in controlling A. flavus. For P. rubens, both essential oils were effective. The linear regression analysis showed that each 1 µL of C. citriodora essential

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Campos, Carolina, Luis Alberto Moreno Ruiz, Rogelio Fragoso‐Soriano, Roberto Y. Sato‐Berrú, Elizabeth Hernández‐Pérez, and Francisco J. Fernández. "Surface‐enhanced Raman spectroscopy and ultrastructural analysis of penicillin‐producing Penicillium rubens strains." Journal of Microscopy 286, no. 1 (2022): 22–30. http://dx.doi.org/10.1111/jmi.13085.

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Al-Rajhi, Aisha M. H., Abdullah Mashraqi, Mohamed A. Al Abboud, et al. "Screening of Bioactive Compounds from Endophytic Marine-Derived Fungi in Saudi Arabia: Antimicrobial and Anticancer Potential." Life 12, no. 8 (2022): 1182. http://dx.doi.org/10.3390/life12081182.

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Nowadays, endophytic fungi represent a rich source of biological active compounds. In the current study, twelve endophytic fungal species were isolated from Avicennia marina leaves. From the isolates, Aspergillus niger, Penicillium rubens and Alternaria alternata recorded the highest isolation frequency (80%), relative density (12.5%) and antimicrobial activity. The antimicrobial and anticancer activities of P. rubens were more effective than those of A. niger and A. alternata; therefore, its identification was confirmed via the ITS rRNA gene. Filtrate extracts of P. rubens, A. alternata and A

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Amsterdam, Daniel. "Recalibration of the Antimicrobial MIC." Journal of Clinical and Laboratory Research 2, no. 4 (2021): 01–02. http://dx.doi.org/10.31579/2768-0487/021.

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In 2009, the World health organization (WHO) referred to the problem of antibiotics and antibiotic resistance stating, “Antibiotic Resistance – one of the three greatest threats to human health.” In 2019 (i.e., just as the COVID-19 pandemic was evolving), more than 2.8 million antibiotic-resistant infections were identified in the United States, resulting in more than 35,000 deaths (CDC 2019). The initial laboratory assay which demonstrated the activity of an antibacterial compound was performed by Alexander Fleming. He showed that an extract from the mold, Penicillium rubens, could inhibit th

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Domínguez-Santos, Rebeca, Katarina Kosalková, Isabel-Clara Sánchez-Orejas, et al. "Characterization of the Gene Encoding S-adenosyl-L-methionine (AdoMet) Synthetase in Penicillium chrysogenum; Role in Secondary Metabolism and Penicillin Production." Microorganisms 10, no. 1 (2021): 78. http://dx.doi.org/10.3390/microorganisms10010078.

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The filamentous fungus Penicillium chrysogenum (recently reidentified as Penicillium rubens) is used in the industrial production of the β-lactam antibiotic penicillin. There are several mechanisms regulating the production of this antibiotic, acting both at the genetic and epigenetic levels, the latter including the modification of chromatin by methyltransferases. S-adenosyl-L-methionine (AdoMet) is the main donor of methyl groups for methyltransferases. In addition, it also acts as a donor of aminopropyl groups during the biosynthesis of polyamines. AdoMet is synthesized from L-methionine an

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Huang, Yuanhao, Lianguo Fu, Yutong Gan, et al. "Analysis of Whole-Genome for Identification of Seven Penicillium Species with Significant Economic Value." International Journal of Molecular Sciences 25, no. 15 (2024): 8172. http://dx.doi.org/10.3390/ijms25158172.

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The Penicillium genus exhibits a broad global distribution and holds substantial economic value in sectors including agriculture, industry, and medicine. Particularly in agriculture, Penicillium species significantly impact plants, causing diseases and contamination that adversely affect crop yields and quality. Timely detection of Penicillium species is crucial for controlling disease and preventing mycotoxins from entering the food chain. To tackle this issue, we implement a novel species identification approach called Analysis of whole GEnome (AGE). Here, we initially applied bioinformatics

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Nègre, Delphine, Abdelhalim Larhlimi, and Samuel Bertrand. "Reconciliation and evolution of Penicillium rubens genome-scale metabolic networks–What about specialised metabolism?" PLOS ONE 18, no. 8 (2023): e0289757. http://dx.doi.org/10.1371/journal.pone.0289757.

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In recent years, genome sequencing of filamentous fungi has revealed a high proportion of specialised metabolites with growing pharmaceutical interest. However, detecting such metabolites through in silico genome analysis does not necessarily guarantee their expression under laboratory conditions. However, one plausible strategy for enabling their production lies in modifying the growth conditions. Devising a comprehensive experimental design testing in different culture environments is time-consuming and expensive. Therefore, using in silico modelling as a preliminary step, such as Genome-Sca

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Hernández-Pérez, Débora Elizabeth, Carlos Gil-Durán, Renato Chávez-Rosales, and Ramon Ovidio Garcia-Rico. "Differential effect of rice husk and xylan on feruloyl esterase activity in Penicillium rubens." Revista MVZ Córdoba 26, no. 1 (2020): e1959. http://dx.doi.org/10.21897/rmvz.1959.

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Objective. Analyzed the effect of xylan and rice husk as sole sources of carbon on the FAE activity and expression of faeA and faeB genes of Penicillium rubens (Wisconsin 54-1255), in submerged fermentation. Materials and methods. The fermentations were carried out for 24, 48, and 72 h (28°C/250 rpm), in flasks with a modified Sakamoto medium. FAE activity was determined using the synthetic substrate Ethyl 4-hydroxy-3-methoxycinnamate. The transcription of faeA and faeB was analyzed by RT-PCR. The PCR products were resolved by electrophoresis and analyzed by densitometry. Results. The analysis

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Siniecka-Kotula, Aleksandra, Martyna Mroczyńska-Szeląg, Anna Brillowska-Dąbrowska, and Lucyna Holec-Gąsior. "Optimized Protocol for RNA Isolation from Penicillium spp. and Aspergillus fumigatus Strains." Current Issues in Molecular Biology 46, no. 11 (2024): 13050–57. http://dx.doi.org/10.3390/cimb46110778.

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Efficient RNA isolation from filamentous fungi is crucial for gene expression studies, but it poses significant technical challenges due to the robust cell walls and susceptibility of RNA to degradation by ribonucleases. This study presents the effectiveness of two RNA isolation protocols for four species of filamentous fungi: Penicillium crustosum, Penicillium rubens, Penicillium griseofulvum, and Aspergillus fumigatus. Both protocols utilized Fenzol Plus for cell lysis but varied in the mechanical disruption methods: bead-beating versus manual vortexing. The results show that the bead-beater

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Sawant, Amol M., Ramu Vankudoth, Vishwambar Navale, et al. "Morphological and molecular characterization of Penicillium rubens sp.nov isolated from poultry feed." Indian Phytopathology 72, no. 3 (2019): 461–78. http://dx.doi.org/10.1007/s42360-019-00165-2.

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Yasser, M. M., A. S. M. Mousa, A. Marzouk Marym, and A. I. Tagyan. "Molecular Identification, Extracellular Enzyme Production and Antimicrobial Activity of Endophytic Fungi Isolated from Solanum tuberosum L. in Egypt." Biosciences, Biotechnology Research Asia 16, no. 1 (2019): 135–42. http://dx.doi.org/10.13005/bbra/2731.

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Solanum tuberosum L. possesses economic properties and can host endophytic mycoflora. A total of 19 endophytic fungi were identified via morphological and molecular methods. Among them, Trichoderma harzianum was the core-group fungus with a relative frequency of 36.7%. In the preliminary antimicrobial assay, all the test pathogens were inhibited by Alternaria tenuissima, Penicillium pinophilum and Penicillium rubens with a maximum inhibition zone of 26 mm and a minimum zone of 11 mm using agar-plug method. All the isolated endophytic fungi produced amylase, while cellulase and tyrosinase were

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Safari Motlagh, Mohammad Reza, Maryam Farokhzad, Behzad Kaviani, and Dariusz Kulus. "Endophytic Fungi as Potential Biocontrol Agents against Sclerotium rolfsii Sacc.—The Causal Agent of Peanut White Stem Rot Disease." Cells 11, no. 17 (2022): 2643. http://dx.doi.org/10.3390/cells11172643.

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Peanut stem white rot caused by Sclerotium rolfsii Sacc. is a soil-borne disease that is widely prevailing across peanut farms, leading to serious economic losses. Screening for biocontrol agents against this pathogen is urgent. In this research, 166 fungal isolates including 136 isolates of S. rolfsii and 30 isolates of antagonistic endophytic fungi were obtained from a total of 220 samples collected from peanut farms in Guilan province, Iran. After morphological and molecular identification, six superior endophytic isolates were finally selected for the in vitro and greenhouse trials, includ

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Sun, Xiaolong, Longfei Yin, Huayue Zhu, et al. "Enhanced Antimicrobial Cellulose/Chitosan/ZnO Biodegradable Composite Membrane." Membranes 12, no. 2 (2022): 239. http://dx.doi.org/10.3390/membranes12020239.

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In this study, chitosan and sugarcane cellulose were used as film-forming materials, while the inorganic agent zinc oxide (ZnO) and natural compound phenyllactic acid (PA) were used as the main bacteriostatic components to fabricate biodegradable antimicrobial composite membranes. The water absorption and antimicrobial properties were investigated by adjusting the concentration of PA. The scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) results demonstrated that the components of the composite membrane were successfully integrated.

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Rajashekar, T. S., Kumar K. Suresh, E. Meghana, T. R. Pavithra, Chowdary Y. Deepthi, and K. Hanumanthayya. "Mystery of the Treatment of Syphilis." JOURNAL OF CLINICAL AND BIOMEDICAL SCIENCES 13, no. 2 (2023): 34–36. http://dx.doi.org/10.58739/jcbs/v13i2.22.117.

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Syphilis is the commonest sexually transmitted disease (STD) affecting humans globally. On 12.10.1492, Christopher Columbus with his crew landed in Haiti (America) and returned to Spain (Europe) on 15th March 1493. Historians believe that, he and his crew members spread the disease syphilis in Europe, which he and his crew members had contracted in Haiti. The migration of people due to war (soldiers and mercenaries), merchants and slave trade contributed to the rapid spread of the disease and it became a pandemic. Initially, syphilis was highly contagious and virulent, affecting millions of pe

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Koleva, Zdravka, Radoslav Abrashev, Maria Angelova, et al. "A Novel Extracellular Catalase Produced by the Antarctic Filamentous Fungus Penicillium Rubens III11-2." Fermentation 10, no. 1 (2024): 58. http://dx.doi.org/10.3390/fermentation10010058.

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Catalase (CAT) is an enzyme involved in the first line of cellular antioxidant defense. It plays a key role in the protection of a wide range of Antarctic organisms against cold stress. Extracellular catalase is very rare and data on it are extremely scarce. The aim of the present study was to select an efficient producer of extracellular catalase from amongst Antarctic filamentous fungi. Sixty-two Antarctic filamentous fungal strains were investigated for their potential ability to synthesize intracellular and extracellular CAT. The Antarctic strain Penicillium rubens III11-2 was selected as

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Laarhoven, Karel A., Hendrik P. Huinink, and Olaf C. G. Adan. "A microscopy study of hyphal growth of Penicillium rubens on gypsum under dynamic humidity conditions." Microbial Biotechnology 9, no. 3 (2016): 408–18. http://dx.doi.org/10.1111/1751-7915.12357.

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Mollerup, Filip, Ville Aumala, Kirsti Parikka, et al. "A family AA5_2 carbohydrate oxidase from Penicillium rubens displays functional overlap across the AA5 family." PLOS ONE 14, no. 5 (2019): e0216546. http://dx.doi.org/10.1371/journal.pone.0216546.

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Bekker, M., H. P. Huinink, O. C. G. Adan, R. A. Samson, T. Wyatt, and J. Dijksterhuis. "Production of an Extracellular Matrix as an Isotropic Growth Phase of Penicillium rubens on Gypsum." Applied and Environmental Microbiology 78, no. 19 (2012): 6930–37. http://dx.doi.org/10.1128/aem.01506-12.

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ABSTRACTIndoor mold represents an important environmental concern, but a fundamental knowledge of fungal growth stages is needed to limit indoor fungal proliferation on finishing materials used in buildings. The present study focused on the succession of germination stages of the common indoor fungusPenicillium rubenson a gypsum substrate. This substrate is used as a model system representing porous materials that are widely used in indoor environments. Imaging with cryo-scanning electron microscopy showed that the formation of an extracellular matrix (ECM) is a phase of the isotropic growth o

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Bekker, M., S. J. F. Erich, S. P. M. Hermanns, M. P. F. H. L. van Maris, H. P. Huinink, and O. C. G. Adan. "Quantifying discoloration caused by the indoor fungus Penicillium rubens on building material at controlled humidity." Building and Environment 90 (August 2015): 60–70. http://dx.doi.org/10.1016/j.buildenv.2015.03.020.

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Yadav, Shweta, and Anand Mishra. "Fungal biosorption of the heavy metals chromium(VI) and nickel from industrial effluent-contaminated soil." Journal of Applied and Natural Science 14, no. 1 (2022): 233–39. http://dx.doi.org/10.31018/jans.v14i1.3297.

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Heavy metals are ubiquitous contaminants that have accompanied man since the earliest ancient times, and unlike other environmental pollutants, they are chemical elements that man does not create or destroy. In the present study, the aim was to determine the biosorption potential of heavy metal-tolerant fungi that were isolated from compost soil samples contaminated by industrial effluents. The isolation was performed on potato dextrose agar (PDA) media supplemented with heavy metals. Chromium-Cr(VI) and nickel-Ni. The most dominant fungal species were found to be Penicillium spp. This fungus

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Requena, Elena, Javier Veloso, Eduardo A. Espeso, and Inmaculada Larena. "Hybrid assembly of Penicillium rubens genomes unveils high conservation of genome structural organisation and the presence of Numts in nuclear DNA." IMA Fungus 16, no. () (2025): e145175. https://doi.org/10.3897/imafungus.16.145175.

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The search for highly accurate chromosomal reference genomes has become a primary objective for the fungal research communities. Various genomic events, including insertions, deletions, inversions and movement of transposable elements, can modify the genomic architecture, resulting in chromosomal rearrangements. Long sequence reads enhance the accuracy and reliability of the assembly procedure, facilitating the study of these genomic characteristics. Here, we have utilised a combination of PacBio and Illumina sequencing technologies to generate hybrid assemblies of <i>Penicillium rubens</i> st

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Flipphi, Michel, Alexandra Márton, Vivien Bíró, et al. "Generation, Transfer, and Loss of Alternative Oxidase Paralogues in the Aspergillaceae Family." Journal of Fungi 9, no. 12 (2023): 1195. http://dx.doi.org/10.3390/jof9121195.

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Alternative oxidase (Aox) is a terminal oxidase operating in branched electron transport. The activity correlates positively with overflow metabolisms in certain Aspergilli, converting intracellular glucose by the shortest possible path into organic acids, like citrate or itaconate. Aox is nearly ubiquitous in fungi, but aox gene multiplicity is rare. Nevertheless, within the family of the Aspergillaceae and among its various species of industrial relevance—Aspergillus niger, A. oryzae, A. terreus, Penicillium rubens—paralogous aox genes coexist. Paralogous genes generally arise from duplicati

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Baiotto, Cristiano S., Luana M. C. Baiotto, Simony C. Beber, et al. "Antifungal effect of essential oils on control of phytopathogens in stored soybean seeds." Revista Brasileira de Engenharia Agrícola e Ambiental 27, no. 4 (2023): 272–78. http://dx.doi.org/10.1590/1807-1929/agriambi.v27n4p272-278.

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ABSTRACT Soybean is subject to occurrences of pathogens transmitted by seeds, requiring phytosanitary treatment, however, it can be toxic to humans and the environment. The objective of this study was to evaluate the effect of essential oils of rosemary (Rosmarinus officinalis) and eucalyptus (Corymbia citriodora) on the control of phytopathogenic fungi in stored soybean seeds. The experiment was carried out in a completely randomized design, using a 2 × 5 factorial arrangement consisted of seeds with and without fungal inoculation (Aspergillus flavus and Penicillium rubens) and five seed trea

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Ruijten, Philip, Hendrik P. Huinink, and Olaf C. G. Adan. "Penicillium rubens germination on desiccated and nutrient-depleted conditions depends on the water activity during sporogenesis." Fungal Biology 124, no. 12 (2020): 1058–67. http://dx.doi.org/10.1016/j.funbio.2020.10.006.

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Dinleyici, M., V. Pérez-Brocal, S. Arslanoglu, et al. "Human milk mycobiota composition: relationship with gestational age, delivery mode, and birth weight." Beneficial Microbes 11, no. 2 (2020): 151–62. http://dx.doi.org/10.3920/bm2019.0158.

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Intestinal and human milk microbiota studies during infancy have shown variations according to geographical location, delivery mode, gestational age, and mother-related factors during pregnancy. In this study, we performed metagenomic mycobiota analyses of 44 transient and mature human milk among five different groups: mothers of normal spontaneous delivery-term (NS-T), caesarean delivery-term (CS-T), premature (PT), small for gestational age (SGA), and large for gestational age (LGA) infants. Fungi were detected in 80 out of the 88 samples. Regarding the number of observed fungal species, the

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Guevara-Suarez, Marcela, Deanna A. Sutton, José F. Cano-Lira, et al. "Identification and Antifungal Susceptibility of Penicillium-Like Fungi from Clinical Samples in the United States." Journal of Clinical Microbiology 54, no. 8 (2016): 2155–61. http://dx.doi.org/10.1128/jcm.00960-16.

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Penicilliumspecies are some of the most common fungi observed worldwide and have an important economic impact as well as being occasional agents of human and animal mycoses. A total of 118 isolates thought to belong to the genusPenicilliumbased on morphological features were obtained from the Fungus Testing Laboratory at the University of Texas Health Science Center in San Antonio (United States). The isolates were studied phenotypically using standard growth conditions. Molecular identification was made using two genetic markers, the internal transcribed spacer (ITS) and a fragment of the β-t

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Cadelis, Melissa, Alex Grey, Shara van de Pas, et al. "Terrien, a metabolite made by Aspergillus terreus, has activity against Cryptococcus neoformans." PeerJ 10 (October 18, 2022): e14239. http://dx.doi.org/10.7717/peerj.14239.

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Antimicrobial compounds, including antibiotics, have been a cornerstone of modern medicine being able to both treat infections and prevent infections in at-risk people, including those who are immune-compromised and those undergoing routine surgical procedures. Their intense use, including in people, animals, and plants, has led to an increase in the incidence of resistant bacteria and fungi, resulting in a desperate need for novel antimicrobial compounds with new mechanisms of action. Many antimicrobial compounds in current use originate from microbial sources, such as penicillin from the fun

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Boruta, Tomasz, and Anna Ścigaczewska. "Enhanced Oxytetracycline Production by Streptomyces rimosus in Submerged Co-Cultures with Streptomyces noursei." Molecules 26, no. 19 (2021): 6036. http://dx.doi.org/10.3390/molecules26196036.

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In the present study, Streptomyces rimosus was confronted with Streptomyces noursei, Penicillium rubens, Aspergillus niger, Chaetomium globosum, or Mucor racemosus in two-species submerged co-cultures in shake flasks with the goal of evaluating the oxytetracycline production and morphological development. The co-culture of S. rimosus with S. noursei exhibited stimulation in oxytetracycline biosynthesis compared with the S. rimosus monoculture, whereas the presence of M. racemosus resulted in a delay in antibiotic production. Different strategies of initiating the “S. rimosus + S. noursei” co-c

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Jami, Mohammad-Saeid, Juan-Francisco Martín, Carlos Barreiro, et al. "Catabolism of phenylacetic acid in Penicillium rubens. Proteome-wide analysis in response to the benzylpenicillin side chain precursor." Journal of Proteomics 187 (September 2018): 243–59. http://dx.doi.org/10.1016/j.jprot.2018.08.006.

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Boruta, Tomasz, Anna Marczyk, Katarzyna Rychta, Karolina Przydacz, and Marcin Bizukojc. "Confrontation between Penicillium rubens and Aspergillus terreus: Investigating the production of fungal secondary metabolites in submerged co-cultures." Journal of Bioscience and Bioengineering 130, no. 5 (2020): 503–13. http://dx.doi.org/10.1016/j.jbiosc.2020.06.012.

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Jothi, Saravanan, and Suneetha Vuppu. "Taguchi analysis and asymmetric keto-reduction of acetophenone and its derivatives by soil filamentous fungal isolate: Penicillium rubens VIT SS1." Preparative Biochemistry & Biotechnology 50, no. 10 (2020): 1042–52. http://dx.doi.org/10.1080/10826068.2020.1786697.

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Segers, Frank J. J., Karel A. van Laarhoven, Hendrik P. Huinink, Olaf C. G. Adan, Han A. B. Wösten, and Jan Dijksterhuis. "The Indoor Fungus Cladosporium halotolerans Survives Humidity Dynamics Markedly Better than Aspergillus niger and Penicillium rubens despite Less Growth at Lowered Steady-State Water Activity." Applied and Environmental Microbiology 82, no. 17 (2016): 5089–98. http://dx.doi.org/10.1128/aem.00510-16.

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ABSTRACTIndoor fungi cause damage in houses and are a potential threat to human health. Indoor fungal growth requires water, for which the terms water activity (aw) and relative humidity (RH) are used. The ability of the fungiAspergillus niger,Cladosporium halotolerans, andPenicillium rubensat different developmental stages to survive changes in awdynamics was studied. Fungi grown on media with high awwere transferred to a controlled environment with low RH and incubated for 1 week. Growth of all developmental stages was halted during incubation at RHs below 75%, while growth continued at 84%

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Wang, Meiyan, Lina Zhao, Xiaoyun Zhang, et al. "Study on biocontrol of postharvest decay of table grapes caused by Penicillium rubens and the possible resistance mechanisms by Yarrowia lipolytica." Biological Control 130 (March 2019): 110–17. http://dx.doi.org/10.1016/j.biocontrol.2018.11.004.

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de Melo Pereira, Dorothy Ívila, Raiana Silveira Gurgel, Anne Terezinha Fernandes de Souza, et al. "Isolation and Identification of Pigment-Producing Endophytic Fungi from the Amazonian Species Fridericia chica." Journal of Fungi 10, no. 1 (2024): 77. http://dx.doi.org/10.3390/jof10010077.

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Pigments of fungal origin have aroused increasing interest in the food dye and cosmetic industries since the global demand for natural dyes has grown. Endophytic microorganisms are a source of bioactive compounds, and Amazonian plant species can harbor fungi with a wide range of biotechnological applications. Popularly known in Brazil as crajiru, Fridericia chica is a medicinal plant that produces a red pigment. In this study, a total of 121 fungi were isolated in potato dextrose agar from three plants. We identified nine pigment-producing endophytic fungi isolated from branches and leaves of

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