Relevant bibliographies by topics / Penk

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Penk'

Author: Grafiati
Published: 4 June 2021
Last updated: 27 April 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Penk.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Penk"

1

Fraser, M., SG Matthews, G. Braems, and T. Jeffray. "Developmental regulation of preproenkephalin (PENK) gene expression in the adrenal gland of the ovine fetus and newborn lamb: effects of hypoxemia and exogenous cortisol infusion." Journal of Endocrinology 155, no. 1 (October 1, 1997): 143–49. http://dx.doi.org/10.1677/joe.0.1550143.

Full text
Abstract:
Development of the fetal adrenal gland is crucial not only for maturation of several fetal organ systems and the initiation of parturition, but also for the development of the fetal response to stress. The enkephalin-related peptides are present in the chromaffin cells of the fetal adrenal medulla and are secreted in response to stress and with sympathetic stimulation. However, changes in expression of preproenkephalin (PENK) with gestation and in response to stress have not been studied in detail. Therefore we examined the developmental pattern of PENK gene expression in the adrenal gland of fetal and newborn lambs, and of adult sheep. We also determined whether levels of PENK mRNA in the fetal adrenal gland changed in response to exogenous glucocorticoids in late gestation, or in response to hypoxemia. Adrenal glands were removed from fetal sheep, lambs and adult sheep at different stages of development for measurement of PENK mRNA. Cortisol was infused (5 micrograms/min) for 12, 24 or 96 h beginning on day 124-129 of gestation. Moderate hypoxemia was induced for 48 h beginning on day 126-130, or at day 134-136 of gestation, by lowering the maternal fractional inspired oxygen. At the end of the treatment periods, the ewes and fetuses were euthanized. Adrenal PENK mRNA were measured by Northern blot analysis. PENK mRNA levels in fetal adrenals were significantly higher (P < 0.05) on days 140-141 of gestation than earlier in pregnancy, and then decreased significantly with the onset of parturition (days 142-146). After cortisol infusion to the fetus for 96 h there was a significant reduction in adrenal PENK mRNA levels. Hypoxemia resulted in a significant increase in PENK mRNA levels in fetuses at day 126-130 of gestation, but not at the later time in pregnancy when endogenous plasma cortisol concentrations were higher. We conclude that there is a decrease in levels of PENK mRNA in the fetal adrenal gland before parturition at the time of the endogenous prepartum rise in plasma cortisol. Hypoxemia led to an elevation of PENK mRNA levels in fetuses at less than 130 days, but after that time, when the basal and stimulated cortisol responses had risen, there was no significant effect of hypoxemia on PENK mRNA. Cortisol infusion to the fetus at this stage of pregnancy resulted in a decrease in adrenal PENK mRNA levels. We suggest that cortisol may play an important role in the regulation of fetal adrenal PENK mRNA levels and enkephalin synthesis by the adrenal gland of the fetal sheep.
APA, Harvard, Vancouver, ISO, and other styles
2

Hartman, Stan J. F., Alexandra J. M. Zwiers, Nadies E. C. van de Water, Joost van Rosmalen, Joachim Struck, Janin Schulte, Oliver Hartmann, et al. "Proenkephalin as a new biomarker for pediatric acute kidney injury – reference values and performance in children under one year of age." Clinical Chemistry and Laboratory Medicine (CCLM) 58, no. 11 (October 25, 2020): 1911–19. http://dx.doi.org/10.1515/cclm-2020-0381.

Full text
Abstract:
AbstractObjectivesAcute kidney injury (AKI) is common in critically ill children, but current biomarkers are suboptimal. Proenkephalin A 119–159 (PENK) is a promising new biomarker for AKI in adults, but pediatric data is lacking. We determined PENK reference intervals for healthy children, crucial for clinical implementation, and explored concentrations in critically ill infants aged under 1 year.MethodsObservational cohort study in healthy infants and critically ill children aged 0–1 years. Reference values were determined using generalized additive models. Plasma PENK concentrations between healthy children and critically ill children with and without AKI, were compared using linear mixed modelling. The performance of PENK as AKI biomarker was compared to cystatin C (CysC) and β-trace protein (BTP) using receiver-operating-characteristic (ROC) analysis.ResultsPENK concentrations in 100 healthy infants were stable during the first year of life (median 517.3 pmol/L). Median PENK concentrations in 91 critically ill children, were significantly higher in those with AKI (n=40) (KDIGO Stage 1 507.9 pmol/L, Stage 2 704.0 pmol/L, Stage 3 930.5 pmol/L) than non-AKI patients (n=51, 432.2 pmol/L) (p < 0.001). PENK appeared to relate better to AKI diagnosis than CysC and BTP (AUROC PENK 0.858, CysC 0.770 and BTP 0.711) in the first 24 h after recruitment.ConclusionsPENK reference values are much higher in young infants than adults, but clearly discriminate between children with and without AKI, with comparable or better performance than CysC and BTP. Our results illustrate the importance of establishing age-normalized reference values and indicate PENK as a promising pediatric AKI biomarker.
APA, Harvard, Vancouver, ISO, and other styles
3

Gruber, Philipp, Felix Fluri, Juliane Schweizer, Andreas Luft, Beat Müller, Mirjam Christ-Crain, and Mira Katan. "Proenkephalin A Adds No Incremental Prognostic Value After Acute Ischemic Stroke." Clinical and Applied Thrombosis/Hemostasis 26 (January 1, 2020): 107602961989531. http://dx.doi.org/10.1177/1076029619895318.

Full text
Abstract:
Objective: The aim of this study was to confirm previous observations that proenkephalin A (PENK-A) may serve as prognostic marker in the setting of acute ischemic stroke in a large stroke cohort. Methods: The plasma concentration of PENK-A was measured within 72 hours of symptom onset in 320 consecutively enrolled patients with stroke. The primary outcome measures were unfavorable functional outcome (modified Rankin Scale score 0-2 vs 3-6) and mortality within 90 days. Logistic and cox proportional regression analyses were fitted to estimate odds ratios (ORs), hazard ratios (HRs) and 95% confidence intervals (CIs), respectively, for the association between PENK-A and the primary outcome measures. Results: After adjusting for demographic and vascular risk factors, PENK-A was neither independently associated with functional outcome (OR: 1.29, 95% CI: 0.16-10.35) nor mortality (HR: 1.02, 95% CI: 0.14-7.33). Conclusion: Among patients with acute stroke, PENK-A does not serve as an independent prognostic marker in this external validation cohort.
APA, Harvard, Vancouver, ISO, and other styles
4

Khorashadi, Mina, Remi Beunders, Peter Pickkers, and Matthieu Legrand. "Proenkephalin: A New Biomarker for Glomerular Filtration Rate and Acute Kidney Injury." Nephron 144, no. 12 (2020): 655–61. http://dx.doi.org/10.1159/000509352.

Full text
Abstract:
Assessment of kidney function is primarily based on urine output and Creatinine (Cr)-based methods to estimate glomerular filtration rate (GFR). The latter is confounded as Cr is not exclusively filtered by the kidney and rises relatively late after the onset of acute kidney injury (AKI). This leads to delays in recognition of reduced kidney function and diagnosis of AKI, particularly in critically ill patients where kidney function can change rapidly. The gold standard methods of GFR determination, such as inulin or iohexol clearance, are labor intensive and unfeasible in acute clinical settings. Proenkephalin A 119–159 (PENK) has been intensively studied as a novel biomarker of kidney function. PENK belongs to the enkephalin peptide family and is freely filtrated in the glomerulus. Plasma PENK concentration appears to correlate strongly with GFR. Moreover, increased plasma PENK concentrations are found to be associated with long-term kidney outcomes and mortality. In this review, we summarize the role of PENK in assessment of kidney function and its capacity to predict various clinical outcomes.
APA, Harvard, Vancouver, ISO, and other styles
5

Abu-Rumeileh, Samir, Peggy Barschke, Patrick Oeckl, Simone Baiardi, Angela Mammana, Andrea Mastrangelo, Mhd Rami Al Shweiki, et al. "Prodynorphin and Proenkephalin in Cerebrospinal Fluid of Sporadic Creutzfeldt–Jakob Disease." International Journal of Molecular Sciences 23, no. 4 (February 12, 2022): 2051. http://dx.doi.org/10.3390/ijms23042051.

Full text
Abstract:
Proenkephalin (PENK) and prodynorphin (PDYN) are endogenous opioid peptides mainly produced in the striatum and, to a lesser extent, in the cerebral cortex. Dysregulated metabolism and altered cerebrospinal fluid (CSF) levels of PENK and PDYN have been described in several neurodegenerative diseases. However, no study to date investigated these peptides in the CSF of sporadic Creutzfeldt–Jakob disease (sCJD). Using liquid chromatography-multiple reaction monitoring mass spectrometry, we evaluated the CSF PDYN- and PENK-derived peptide levels in 25 controls and 63 patients with sCJD belonging to the most prevalent molecular subtypes (MM(V)1, VV2 and MV2K). One of the PENK-derived peptides was significantly decreased in each sCJD subtype compared to the controls without a difference among subtypes. Conversely, PDYN-derived peptides were selectively decreased in the CSF of sCJD MV2K, a subtype with a more widespread overall pathology compared to the sCJD MM(V)1 and the VV2 subtypes, which we confirmed by semiquantitative analysis of cortical and striatal neuronal loss and astrocytosis. In sCJD CSF PENK and PDYN were associated with CSF biomarkers of neurodegeneration but not with clinical variables and showed a poor diagnostic performance. CSF PDYN and PENK-derived peptides had no significant diagnostic and prognostic values in sCJD; however, the distinct marker levels between molecular subtypes might help to better understand the basis of phenotypic heterogeneity determined by divergent neuronal targeting.
APA, Harvard, Vancouver, ISO, and other styles
6

Mao, Hua, Yong You, Lifen Tong, Xiaohe Tang, Renbo Wei, and Xiaobo Liu. "Dielectric properties of poly(arylene ether nitrile ketone) copolymers." High Performance Polymers 31, no. 8 (November 5, 2018): 901–8. http://dx.doi.org/10.1177/0954008318808570.

Full text
Abstract:
A series of poly(arylene ether nitrile ketone) (PENK) random copolymers are successfully synthesized by the nucleophilic aromatic substitution polymerization of 2,6-dichlorobenzonitrile, 4,4′-difluorobenzophenone with various bisphenol monomers (4,4′-biphenol, bisphenol A, phenolphthalein, and hydroquinone). Compared with poly(arylene ether ketone), the PENK copolymers possess better solubility in polar solvents such as N-methyl-2-pyrrolidone, N, N-dimethylacetamide, N, N-dimethylformamide, dimethylsulfoxide, and so on. Because of the different molecular structures, the PENK copolymers exhibit thermal properties with their glass transition temperature ( T g) in the range of 171–237°C and 5% weight loss temperature ( T d) ranging from 409°C to 554°C. Moreover, all polymers with an intrinsic viscosity of approximately 1 dL/g show excellent film-forming properties and outstanding mechanical strength higher than 85 MPa. The temperature dependence of the dielectric constant and dielectric loss of all derived copolymers is stable before their T g. The breakdown strength of the hydroquinone-derived PENK copolymer is as high as 253 kV/mm, resulting in an energy storage density of 1.00 J/cm3. These solvent processable PENK copolymers are potential dielectric candidates for high temperature applications.
APA, Harvard, Vancouver, ISO, and other styles
7

Weber, James L., and Paula E. May. "Dinucleotide repeat polymorphism at the PENK locus." Nucleic Acids Research 18, no. 8 (1990): 2200. http://dx.doi.org/10.1093/nar/18.8.2200.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Comings, David E., Hezekiah Blake, George Dietz, Radhika Gade-Andavolu, Richard S. Legro, Gerard Saucier, Patrick Johnson, Ray Verde, and James P. MacMurray. "The proenkephalin gene (PENK) and opioid dependence." NeuroReport 10, no. 5 (April 1999): 1133–35. http://dx.doi.org/10.1097/00001756-199904060-00042.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Wan, Yong, Casey White, Nadine Robert, Matthew B. Rogers, and Heather L. Szabo-Rogers. "Localization of Tfap2β, Casq2, Penk, Zic1, and Zic3 Expression in the Developing Retina, Muscle, and Sclera of the Embryonic Mouse Eye." Journal of Histochemistry & Cytochemistry 67, no. 12 (October 22, 2019): 863–71. http://dx.doi.org/10.1369/0022155419885112.

Full text
Abstract:
Optic development involves sequential interactions between several different tissue types, including the overlying ectoderm, adjacent mesoderm, and neural crest mesenchyme and the neuroectoderm. In an ongoing expression screen, we identified that Tfap2β, Casq2, Penk, Zic1, and Zic3 are expressed in unique cell types in and around the developing eye. Tfap2β, Zic1, and Zic3 are transcription factors, Casq2 is a calcium binding protein and Penk is a neurotransmitter. Tfap2β, Zic1, and Zic3 have reported roles in brain and craniofacial development, while Casq2 and Penk have unknown roles. These five genes are expressed in the major tissue types in the eye, including the muscles, nerves, cornea, and sclera. Penk expression is found in the sclera and perichondrium. At E12.5 and E15.5, the extra-ocular muscles express Casq2, the entire neural retina expresses Zic1, and Zic3 is expressed in the optic disk and lip of the optic cup. The expression of Tfap2β expanded from corneal epithelium to the neural retina between E12.5 to E15.5. These genes are expressed in similar domains as Hedgehog ( Gli1, and Ptch1) and the Wnt ( Lef1) pathways. The expression patterns of these five genes warrant further study to determine their role in eye morphogenesis:
APA, Harvard, Vancouver, ISO, and other styles
10

Shime, Hiroaki, Mizuyu Odanaka, Makoto Tsuiji, Takuma Matoba, Masaki Imai, Yoshiaki Yasumizu, Ryuta Uraki, et al. "Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function." Proceedings of the National Academy of Sciences 117, no. 34 (August 7, 2020): 20696–705. http://dx.doi.org/10.1073/pnas.2000372117.

Full text
Abstract:
Regulatory T (Treg) cells, expressing CD25 (interleukin-2 receptor α chain) and Foxp3 transcription factor, maintain immunological self-tolerance and suppress various immune responses. Here we report a feature of skin Treg cells expanded by ultraviolet B (UVB) exposure. We found that skin Treg cells possessing a healing function are expanded by UVB exposure with the expression of an endogenous opioid precursor, proenkephalin (PENK). Upon UVB exposure, skin Treg cells were expanded with a unique TCR repertoire. Also, they highly expressed a distinctive set of genes enriched in “wound healing involved in inflammatory responses” and the “neuropeptide signaling pathway,” as indicated by the high expression ofPenk.We found that not only was PENK expression at the protein level detected in the UVB-expanded skin Treg (UVB-skin Treg) cells, but that a PENK-derived neuropeptide, methionine enkephalin (Met-ENK), from Treg cells promoted the outgrowth of epidermal keratinocytes in an ex vivo skin explant assay. Notably, UVB-skin Treg cells also promoted wound healing in an in vivo wound closure assay. In addition, UVB-skin Treg cells produced amphiregulin (AREG), which plays a key role in Treg-mediated tissue repair. Identification of a unique function of PENK+UVB-skin Treg cells provides a mechanism for maintaining skin homeostasis.
APA, Harvard, Vancouver, ISO, and other styles
More sources

Dissertations / Theses on the topic "Penk"

1

Penk, Katy [Verfasser], Detlef [Akademischer Betreuer] Gabel, and Dieter [Akademischer Betreuer] Wöhrle. "Dodecaboratclusterhaltige Membranen für Brennstoffzellen / Katy Penk. Gutachter: Detlef Gabel ; Dieter Wöhrle. Betreuer: Detlef Gabel." Bremen : Staats- und Universitätsbibliothek Bremen, 2014. http://d-nb.info/1072225808/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Penk, Katy [Verfasser], Detlef Akademischer Betreuer] Gabel, and Dieter [Akademischer Betreuer] [Wöhrle. "Dodecaboratclusterhaltige Membranen für Brennstoffzellen / Katy Penk. Gutachter: Detlef Gabel ; Dieter Wöhrle. Betreuer: Detlef Gabel." Bremen : Staats- und Universitätsbibliothek Bremen, 2014. http://nbn-resolving.de/urn:nbn:de:gbv:46-00103875-17.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Penk, Christiane Verfasser], Petra [Akademischer Betreuer] [Stanat, and Olaf [Akademischer Betreuer] Köller. "Effekte von Testteilnahmemotivation auf Testleistung im Kontext von Large-Scale-Assessments / Christiane Penk. Gutachter: Petra Stanat ; Olaf Köller." Berlin : Kultur-, Sozial- und Bildungswissenschaftliche Fakultät, 2015. http://d-nb.info/1071885987/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Penk, Christiane [Verfasser], Petra [Akademischer Betreuer] Stanat, and Olaf [Akademischer Betreuer] Köller. "Effekte von Testteilnahmemotivation auf Testleistung im Kontext von Large-Scale-Assessments / Christiane Penk. Gutachter: Petra Stanat ; Olaf Köller." Berlin : Kultur-, Sozial- und Bildungswissenschaftliche Fakultät, 2015. http://d-nb.info/1071885987/34.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

MONNIER, DOMINIQUE. "Regulations transcriptionnelles des genes de la proopiomelanocortine (pomc) et de la proenkephaline (penk) par le pituitary adenylate cyclase-activating polypeptide (pacap)." Université Louis Pasteur (Strasbourg) (1971-2008), 1995. http://www.theses.fr/1995STR13214.

Full text
Abstract:
Le pituitary adenylate cyclase activating polypeptide (pacap) est un neurotransmetteur des systemes nerveux centraux et peripheriques, existant sous deux formes: le pacap 27 le pacap 38. Trois types de recepteurs de ce peptide sont caracterises. Le recepteur de type i peut activer deux voies de messageries intracellulaires distinctes: celle dependant de l'ampc et celle dependant des phosphatidyls inositols. L'objet de cette etude est l'analyse du role regulateur du pacap sur l'expression de deux genes hormonaux: la pro-opiomelanocortine (pomc) et la pro-enkephaline (penk). Ces genes codent des peptides opiaces impliques dans la reponse au stress. Les effets transcriptionnels du pacap sont etudies dans deux modeles experimentaux: la lignee cellulaire att20 derivee de cellules corticotropes hypophysaires et la lignee cellulaire pc12 derivee de cellules chromaffines surrenaliennes. En utilisant des genes chimeres associant les regions promotrices des genes de la pomc ou de la penk au gene bacterien codant la chloramphenicol acetyl transferase (cat), nous montrons que les pacap 27 et 38 stimulent l'activite transcriptionnelle de ces deux promoteurs dans les cellules att20 et pc12. Dans les deux modeles, la proteine kinase a (pka) est un relais obligatoire. En effet, l'inactivation genetique de cette enzyme abolit les effets du pacap sur les genes pomc et penk. Une analyse fine des mecanismes de transactivation montre que ces genes sont regules par des facteurs de transcription pre-existants et/ou neosynthetises. L'utilisation de mutants dominants inhibiteurs de ces facteurs permet de montrer que le pacap regule la transcription des genes pomc et penk via le complexe ap-1 (famille fos/jun) et le facteur creb
APA, Harvard, Vancouver, ISO, and other styles
6

Mengoli, Andrea. "Progettazione e sviluppo di un?applicazione iOS per la gestione di partite di beach tennis." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amslaurea.unibo.it/13316/.

Full text
Abstract:
Lo sport è spesso una forte passione, alla quale però non si riesce a dedicare il tempo voluto a causa dei numerosi impegni personali; questi impegni variano da individuo a individuo e di conseguenza è difficile trovare compagni con cui praticare la stessa attività. Questo problema si avverte maggiormente negli sport di gruppo; infatti se per fare una corsa è sufficiente molta forza di volontà e un po’ di tempo libero, per giocare a tennis, calcio, basket, o anche ai più recenti beach tennis e beach volley, oltre al tempo libero, serve un campo e qualche compagno di gioco. Tutto ciò crea disagio a ciascun giocatore poiché colui che rinuncia alla partita mette in difficoltà i propri compagni che si ritrovano con un uomo in meno, con il rischio di dover rinunciare al match e in alcuni casi con l’aggravante di dover pagare comunque il costo del campo precedentemente prenotato. Al contrario può accadere che una persona si ritrovi con molto tempo libero ma senza compagni con cui giocare: questo si verifica frequentemente in vacanza, dove l’individuo, solitamente in un posto nuovo, non conosce persone con coi condividere e praticare lo sport che ama. È evidente che i due problemi siano complementari, di conseguenza creando un sistema di connessioni fra richiedenti e offerenti sarebbe possibile risolvere entrambe le questioni. Dopo un’attenta analisi di metodi alternativi per la risoluzione del problema e a seguito di approfondite ricerche, è stata progettata una nuova soluzione che combina i vantaggi delle chat, ovvero la rapidità d’informazione e il target mirato composto solo da appassionati dello sport, con un potenziale maggiore di diffusione della richiesta. Questo è possibile attraverso la creazione di un’app che incroci le diverse esigenze favorendo le connessioni tra sportivi.
APA, Harvard, Vancouver, ISO, and other styles
7

Aresh, Bejan. "Functional Aspects of Peripheral and Spinal Cord Neurons Involved in Itch and Pain." Doctoral thesis, Uppsala universitet, Genetisk utvecklingsbiologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-284070.

Full text
Abstract:
We have investigated the role of the metabotropic glutamate receptor 7 (mGluR7) and the gastrin releasing peptide receptor (Grpr) population that are involved at different levels of itch transmission. We found that mGuR7 deficient mice displayed an anaphylaxis-like behavior when provoked with histamine. Analysis of blood revealed elevated plasma levels of histamine and mouse mast cell protease-1 (mMCP1), two indicators of anaphylaxis, in mGluR7 deficient mice compared with control mice. Inhibition of the neurokinin 1 receptor, by preventing binding of the corresponding ligand substance P (SP), prior to provocation with histamine prevented the development of anaphylaxis in mGluR7 deficient animals. However, blocking GRPR (gastrin releasing peptide receptor) only resulted in decreased itch levels in mGluR7 deficient mice but did not prevent the systemic anaphylaxis-like behavior. Our findings indicate that mGluR7 normally functions as a brake on histaminergic itch that is mediated through GRPR as well as anaphylaxis through Substance P. Grpr has previously been shown to mediate both histaminergic and non-histaminergic itch but little is known about the GRPR neuronal population. We used a BAC cloning strategy to construct a Grpr-Cre line, which we crossed with the reporter lines tdTomato and Viaat-egfp as well as with Vglut2-lox. We could conclude that Grpr-Cre neurons are mainly excitatory interneurons located in lamina II-IV, that convey itch using VGLUT2-mediated glutamatergic transmission to the next, currently unknown, step in the labeled line of chemical itch. To eventually deduce the function of the endogenous opioids dynorphin and enkephalin, which are hypothesized to be involved in gating pain and itch in the spinal cord, we constructed two Cre lines using BAC cloning that targeted the precursor proteins preprodynorphin and preproenkephalin, respectively. Preprodynorphin-Cre neurons were mainly located in lamina II-IV and overlapped to 47% with Vglut2 mRNA, while the co-expression with the inhibitory markers Viaat-egfp and PAX2 was 13% and 28% respectively in the spinal cord. Preproenkephalin neurons were more localized to lamina III in the dorsal horn, furthermore single cell analysis showed that they overlapped to 94% with Vglut2 mRNA while 7% and 13% expressed Viaat-egfp and PAX2 respectively.
APA, Harvard, Vancouver, ISO, and other styles
8

Monte, Fernando Ferreira Del. "Desenvolvimento de elementos de fixação (âncoras de suturas) em materiais biocompatíveis através de processo de Manufatura Aditiva." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/18/18146/tde-04052017-103304/.

Full text
Abstract:
Atualmente a área de saúde vem buscando auxílio na engenharia para a contribuição no estudo e confecção de próteses para casos específicos de fraturas ou doenças ósseas. Com o avanço da tecnologia surgiram processos de manufatura que tornam possível a fabricação de próteses personalizadas. Uma dessas tecnologias é a manufatura aditiva. O grande desafio no momento está na fabricação de próteses por manufatura aditiva que combinem desempenho biomecânico e resistência estrutural. Nesse contexto, o objetivo deste trabalho é desenvolver elementos de fixação, especificamente âncoras de sutura de polímeros PEEK e PEKK, considerando seus requisitos estruturais através de simulações pelo método dos elementos finitos, e considerando que sejam fabricadas através de processos de manufatura aditiva. Este desenvolvimento permitirá a substituição de âncoras de sutura de liga de titânio, hoje largamente empregadas pelos cirurgiões, por âncoras de sutura de polímeros biocompatíveis, o que possibilitará que estes polímeros sejam absorvidos pelo corpo humano em curto e médio prazo, permitindo a completa restituição do osso afetado, melhorando a qualidade de vida do paciente pós-cirurgia. Os resultados obtidos neste trabalho indicam que a técnica poderá resultar em próteses com a biocompatibilidade desejada e resistência mecânica adequada. Próteses permanentes (articulações) ou provisórias (âncoras de sutura) seriam um dos critérios para a escolha do material a ser utilizado, absorvível ou não pelo corpo humano.
Nowadays medicine is searching assistance from engineering that may contribute in studies and confection of prothesis to specific cases of fractures and bone diseases. With the advance of technology new processes of manufacture were risen, making possible the confection of personalized prothesis. The biggest challenge of the moment is in the manufacture of additive prothesis that can combine biomechanics performance and structural resistance. In this context, the objective of this dissertation is to develop PEEK and PEKK polymer suture anchors, considering its structural requirements, taking into account their mechanical strength, through simulation by the finite element method, and considering additive manufacturing processes. This development will allow the replacement of titanium alloy suture anchors, now widely used by surgeons by suture anchors of biocompatible polymers, which enable these polymers to be absorbed by the human body in the short and medium term, allowing full regeneration of affected bone, improving the quality of life of the patient. The results of this study indicate that the technique could result in prosthesis with the desired biocompatibility and adequate mechanical strength. Permanent prosthesis (joints) or temporary (suture anchors) would be one of the criteria for the choice of material to be used, absorbable or non absorbable by the human body.
APA, Harvard, Vancouver, ISO, and other styles
9

Dumoulin, Emmanuel. "Fabrication additive de pièces en polymères thermoplastiques hautes performances et en polyamide 12 par le procédé de frittage sélectif par laser." Phd thesis, Ecole Nationale Supérieure des Mines de Paris, 2014. http://pastel.archives-ouvertes.fr/pastel-01021861.

Full text
Abstract:
Le frittage sélectif par laser (ou Selective Laser Sintering, SLS) des poudres polymères thermoplastiques est maintenant une technique répandue de fabrication additive. Néanmoins, ce procédé n'est industriellement mature que pour une seule famille de polymères, les polyamides. Pour que ce procédé soit employé dans la fabrication de pièces subissant des contraintes thermiques au-delà de 50 °C, il est ainsi nécessaire d'étendre la gamme des matériaux utilisables à des polymères hautes performances tels que les poly(aryl-éther-cétone) ou les poly(aryl-imide). Cette étude décrit la fabrication additive, couche par couche, de pièces aérospatiales complexes en polymères hautes performances. Pour cela, sept poudres en polymère ont été sélectionnées afin d'étudier l'influence de celles-ci sur les différentes phases du procédé et sur la qualité de la matière frittée/fondue. Ainsi, la morphologie de leurs particules, leurs microstructures ou encore leurs densités versées et tapées sont analysées, de même que leurs stabilités thermiques, leurs capacités à absorber l'eau ou à s'écouler. Dans un second temps, une étude paramétrique du procédé a été réalisée dans le but d'aboutir à la fabrication de pièces de bonne qualité matière, tout en portant un intérêt vis-à-vis des évolutions de la poudre cycle après cycle de fabrication. De plus, il est important, dans un souci d'optimisation, d'utiliser toutes les possibilités de forme qu'offre cette fabrication additive et d'en évaluer la résistance mécanique. C'est pourquoi une loi de comportement mécanique d'un polyamide 12 consolidé sélectivement par laser a été déterminée et implémentée dans un code de calcul par éléments finis (ZéBuLoN®). Cette loi de comportement, dans le domaine linéaire et non linéaire, représentative de l'anisotropie du matériau, a ensuite été validée expérimentalement sur des éprouvettes d'essais mécaniques et sur un démonstrateur aérospatial.
APA, Harvard, Vancouver, ISO, and other styles
10

Shepherd, Verene Albertha. "Pens and pen-keepers in a plantation society : aspects of Jamaican social and economic history, 1740-1845." Thesis, University of Cambridge, 1988. https://www.repository.cam.ac.uk/handle/1810/272366.

Full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Books on the topic "Penk"

1

The technical pen. New York: Watson-Guptill, 1992.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
2

Pasahow, Edward. 1996-1997 Parker pen encyclopedia and data book: A compendium of writing instrument lore and history. [Descanso, CA] (PO Box 205, Descanso 91916): [Ed Pasahow Books, 1996.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
3

Gang bi: Xian chang xie sheng. Shenyang: Liaoning mei shu chu ban she, 2001.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
4

McCurdy, Hershellene Peek. Peak, Peek, Peake, 1765-1991: Some ancestors and descendants of Solomon Peek and Mary Vickery Peek. [Jacksonville, Ala.] (802 4th Ave. NE, Jacksonville 36265): H.P. McCurdy, 1991.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
5

Moak, David L. Mabie in America: Writing instruments from 1843-1941. [Jackson, Miss.?]: D. Moak, 2003.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
6

Moak, David L. Mabie in America: Writing instruments from 1843-1941. 3rd ed. [United States]: Mabie, Todd & Co., 2007.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
7

Cousins, Lucy. Peck, peck, peck. Somerville, Massachusetts: Candlewick Press, 2013.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
8

Peck, peck, peck. Vero Beach, FL: Rourke Pub., 2008.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
9

xi, Tong xi. Peng peng peng. Shen yang: Chun feng wen yi chu ban she, 2003.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
10

Peck, peck, peck. London: Walker Books, 2014.

Find full text
APA, Harvard, Vancouver, ISO, and other styles
More sources

Book chapters on the topic "Penk"

1

Weik, Martin H. "peak-to-peak value." In Computer Science and Communications Dictionary, 1243. Boston, MA: Springer US, 2000. http://dx.doi.org/10.1007/1-4020-0613-6_13763.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Weik, Martin H. "peak." In Computer Science and Communications Dictionary, 1241. Boston, MA: Springer US, 2000. http://dx.doi.org/10.1007/1-4020-0613-6_13749.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Arndt, T. "Peak." In Springer Reference Medizin, 1844. Berlin, Heidelberg: Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-48986-4_2369.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Arndt, T. "Peak." In Lexikon der Medizinischen Laboratoriumsdiagnostik, 1. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-49054-9_2369-1.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Gooch, Jan W. "PEEK." In Encyclopedic Dictionary of Polymers, 522. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_8512.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Dean, Karen, and Sam Humphrey. "Peak." In Coaching Stories, 63–69. Abingdon, Oxon ; New York, NY : Routledge, 2019.: Routledge, 2019. http://dx.doi.org/10.4324/9780429428227-8.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Allen, Patricia Melton, Frances E. Alston, and Emily Millikin DeKerchove. "Defining peak performance and why it matters." In Peak Performance, 1–14. Boca Raton : CRC Press, Taylor & Francis, 2019. |: CRC Press, 2019. http://dx.doi.org/10.1201/9780429451508-1.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Allen, Patricia Melton, Frances E. Alston, and Emily Millikin DeKerchove. "Principles of lean to optimize business outcomes." In Peak Performance, 15–40. Boca Raton : CRC Press, Taylor & Francis, 2019. |: CRC Press, 2019. http://dx.doi.org/10.1201/9780429451508-2.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Allen, Patricia Melton, Frances E. Alston, and Emily Millikin DeKerchove. "Principles of human performance and performance modes." In Peak Performance, 41–64. Boca Raton : CRC Press, Taylor & Francis, 2019. |: CRC Press, 2019. http://dx.doi.org/10.1201/9780429451508-3.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Allen, Patricia Melton, Frances E. Alston, and Emily Millikin DeKerchove. "Human error defenses." In Peak Performance, 65–108. Boca Raton : CRC Press, Taylor & Francis, 2019. |: CRC Press, 2019. http://dx.doi.org/10.1201/9780429451508-4.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Penk"

1

Henning, A. K., J. Fragala, R. Shile, and P. Simao. "Piezoresistive pens for dip-pen nanolithography." In SPIE MOEMS-MEMS, edited by Holger Becker and Bonnie L. Gray. SPIE, 2013. http://dx.doi.org/10.1117/12.2008785.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Geslin, Alexis, Clément Paul, Philippe Bussi, Robert Barsotti, Jonathon Hollahan, and Mary Calvin. "PEKK Poly Ether Ketone Ketone for High Temperature High Pressure Oil & Gas Conditions." In Offshore Technology Conference. OTC, 2021. http://dx.doi.org/10.4043/30987-ms.

Full text
Abstract:
Abstract Poly Aryl Ether Ketones (PAEK), and in particular Poly Ether Ether Ketone (PEEK), have established themselves as polymers of choice for extreme environments. This is especially true in the Oil & Gas industry, with its very harsh conditions (high temperatures, high pressures and corrosive fluids). Within the PAEK family, Poly Ether Ketone (PEK) and Poly Ether Ketone Ether Ketone Ketone (PEKEKK) were later introduced to address the need for higher mechanical and thermal properties than PEEK; unfortunately, their chemical resistance has been reported as not matching that of PEEK. In this paper, we report on novel, high viscosity, Poly Ether Ketone Ketone (PEKK) polymers that combine PEEK-like processing, high mechanical performances, barrier properties and very good chemical resistance in the NORSOK M710 test, positioning PEKK as a strong candidate for demanding Oil & Gas applications, such as O-rings, seals or electrical connectors.
APA, Harvard, Vancouver, ISO, and other styles
3

Wasilah, Wasilah, and Andi Hildayanti. "Sistem Struktur Tiang Bengkok Pada Rumah Suku Kajang Bulukumba." In Seminar Peng-Konteks-an Arsitektur Nusantara. Ikatan Peneliti Lingkungan Binaan Indonesia, 2018. http://dx.doi.org/10.32315/sem.2.a001.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Choandi, Mieke, and Sutrisno Muriyoso. "Kajian Arsitektur Kelenteng di Jawa Bagian Barat." In Seminar Peng-Konteks-an Arsitektur Nusantara. Ikatan Peneliti Lingkungan Binaan Indonesia, 2018. http://dx.doi.org/10.32315/sem.2.a009.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Rijal, Muhammad, Bambang Setioko, and Agung Budi Sardjono. "Konfigurasi Ruang Permukiman di Pulau Penyengat." In Seminar Peng-Konteks-an Arsitektur Nusantara. Ikatan Peneliti Lingkungan Binaan Indonesia, 2018. http://dx.doi.org/10.32315/sem.2.a019.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Imran, Mohammad. "Formulasi/Persamaan Reduksi Kebisingan di Area Sempadan SMP Negeri 6 Gorontalo." In Seminar Peng-Konteks-an Arsitektur Nusantara. Ikatan Peneliti Lingkungan Binaan Indonesia, 2018. http://dx.doi.org/10.32315/sem.2.a023.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Mukhtar, Mukhlis A. "Tahapan Pembangunan Rumah Tradisional SAO RIA sebagai Upaya Pelestarian Masyarakat Adat Suku Lio Dusun Nuaone Ende." In Seminar Peng-Konteks-an Arsitektur Nusantara. Ikatan Peneliti Lingkungan Binaan Indonesia, 2018. http://dx.doi.org/10.32315/sem.2.a028.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Singarimbun, Aldo Putra, Ikaputra Ikaputra, and Dimas Wihardyanto. "Karakteristik Fasade Bangunan Pada Kawasan Kesawan Di Kota Medan (Studi Kasus Koridor Jalan Ahmad Yani, Kesawan, Medan)." In Seminar Peng-Konteks-an Arsitektur Nusantara. Ikatan Peneliti Lingkungan Binaan Indonesia, 2018. http://dx.doi.org/10.32315/sem.2.a037.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Agusintadewi, Ni Ketut. "Hakekat Paon sebagai Wujud Dimensi Spiritual Hunian Tradisional Bali Aga di Bali Tengah." In Seminar Peng-Konteks-an Arsitektur Nusantara. Ikatan Peneliti Lingkungan Binaan Indonesia, 2018. http://dx.doi.org/10.32315/sem.2.a042.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Lindarto, Dwi. "Arsitektur Si Waluh Jabu Karo : Arsitektur Tanggap Angin." In Seminar Peng-Konteks-an Arsitektur Nusantara. Ikatan Peneliti Lingkungan Binaan Indonesia, 2018. http://dx.doi.org/10.32315/sem.2.a050.

Full text
APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "Penk"

1

Gesing, Leah, Anna K. Johnson, Kenneth J. Stalder, Matthew Ritter, Jim Moody, Tara Donovan, Eva Jablonski, Dave Johnson, and Angie Johnson. Changing Pen Configuration From Small to Large Pens: How Does this Change Resource Use for the Growing Pig? Ames (Iowa): Iowa State University, January 2011. http://dx.doi.org/10.31274/ans_air-180814-846.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Ogden, Kate, Carl Emmerson, and Rowena Crawford. DC PENS. Institute for Fiscal Studies, January 2022. http://dx.doi.org/10.1920/bn.ifs.2022.bn0338.

Full text
APA, Harvard, Vancouver, ISO, and other styles
3

Dahleh, Munther A. Robust Controller Design: Minimizing Peak-to-Peak Gain. Fort Belvoir, VA: Defense Technical Information Center, September 1992. http://dx.doi.org/10.21236/ada460049.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Rogoff, Kenneth, and Yuanchen Yang. Peak China Housing. Cambridge, MA: National Bureau of Economic Research, August 2020. http://dx.doi.org/10.3386/w27697.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Golbeck, John. 2014 Penn State Bioinorganic Workshop. Office of Scientific and Technical Information (OSTI), October 2015. http://dx.doi.org/10.2172/1221965.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Krebs, Carsten. 4th Penn State Bioinorganic Workshop. Office of Scientific and Technical Information (OSTI), August 2017. http://dx.doi.org/10.2172/1375808.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Walter White Tail Feather. Fort Peck Reservations Wind Project. Office of Scientific and Technical Information (OSTI), August 2007. http://dx.doi.org/10.2172/915088.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Englin, J. E., J. G. De Steese, R. W. Schultz, and M. A. Kellogg. Peak load management: Potential options. Office of Scientific and Technical Information (OSTI), October 1989. http://dx.doi.org/10.2172/5314251.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Tan, C. Y. Peak finding using biorthogonal wavelets. Office of Scientific and Technical Information (OSTI), February 2000. http://dx.doi.org/10.2172/750842.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

McMechan, M. E., and G. B. Leech. Geology, Tangle Peak, British Columbia. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2011. http://dx.doi.org/10.4095/287454.

Full text
APA, Harvard, Vancouver, ISO, and other styles
You might also be interested in the extended bibliographies on the topic 'Penk' for particular source types:
Journal articles Dissertations / Theses Books
We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

To the bibliography