Academic literature on the topic 'Pentamethine cyanine dyes'

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Journal articles on the topic "Pentamethine cyanine dyes"

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Hassan, Abazied Shindy, Abdallah El-Maghraby Mohamed, Mubark Goma Maha, and Abdelrahman Harb Nemat. "Dicarbocyanine and tricarbocyanine dyes: Novel synthetic approaches, photosensitization evaluation and antimicrobial screening." Chemistry International 6, no. 1 (2020): 30–41. https://doi.org/10.5281/zenodo.2631739.

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Novel dicarbocyanine dyes (pentamethine cyanine dyes), bis dicarbocyanine dyes (bis pentamethine cyanine dyes), tricarbocyanine dyes (heptamethine cyanine dyes) and bis tricarbocyanine dyes (bis heptamethine cyanine dyes) derived from the nucleus of furo[(3,2-d)pyrazole; (3',2'-d)oxazole] were prepared using novel synthetic approaches. The electronic visible absorption spectra were investigated in 95% ethanol to evaluate the photosensitization properties. The cyanine dyes were better photosensitizers in visible light to initiate the electronic transitions at higher wavelength bands (ba
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Slavicek, Petr, Šárka Paušová, and Karel Bouzek. "Thermal Truncation of Heptamethine Cyanine Dyes." Journal of the American Chemical Society 146, no. 29 (2024): 19768–81. https://doi.org/10.1021/jacs.4c02116.

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Cyanine dyes are a class of organic, usually cationic molecules containing two nitrogen centers linked through conjugated polymethine chains. Unlike phototruncation, the thermal truncation (chain-shortening) reaction is a phenomenon that has rarely been described for these important fluorophores. Here, we present a systematic investigation of the truncation of heptamethine cyanines (Cy7) to pentamethine (Cy5) and trimethine (Cy3) cyanines via homogeneous, acid-base catalyzed nucleophilic exchange reactions. We demonstrate how different substituents at the C3′ and C4′ positions of t
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Chapman, Gala, Maged Henary, and Gabor Patonay. "The Effect of Varying Short-Chain Alkyl Substitution on the Molar Absorptivity and Quantum Yield of Cyanine Dyes." Analytical Chemistry Insights 6 (January 2011): ACI.S6568. http://dx.doi.org/10.4137/aci.s6568.

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The effect of varying short-chain alkyl substitution of the indole nitrogens on the spectroscopic properties of cyanine dyes was examined. Molar absorptivities and fluorescence quantum yields were determined for a set of pentamethine dyes and a set of heptamethine dyes for which the substitution of the indole nitrogen was varied. For both sets of dyes, increasing alkyl chain length resulted in no significant change in quantum yield or molar absorptivity. These results may be useful in designing new cyanine dyes for analytical applications and predicting their spectroscopic properties.
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Dost, Tyler L., Michael T. Gressel, and Maged Henary. "Synthesis and Optical Properties of Pentamethine Cyanine Dyes With Carboxylic Acid Moieties." Analytical Chemistry Insights 12 (January 1, 2017): 117739011771193. http://dx.doi.org/10.1177/1177390117711938.

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Cyanine dyes possessing carboxylic acid groups have been used in many different fields of study. The acid groups can act as handles for bioconjugation or as metal chelators. Several pentamethine cyanine dyes with propionic acid handles were synthesized and their optical properties were studied to determine their usefulness as fluorescent probes. The optical properties studies performed include the absorbance and emission maxima values as well as the calculation of quantum yield and molecular brightness levels. Molecular models were also calculated to help analyze the dyes’ behavior and were co
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Aristova, D., G. Volynets, S. Chernii, et al. "Far-red pentamethine cyanine dyes as fluorescent probes for the detection of serum albumins." Royal Society Open Science 7, no. 7 (2020): 200453. http://dx.doi.org/10.1098/rsos.200453.

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Benzothiazole based cyanine dyes with bridged groups in the pentamethine chain were studied as potential far-red fluorescent probes for protein detection. Spectral-luminescent properties were characterized for unbound dyes and in the presence of serum albumins (bovine (BSA), human (HSA), equine (ESA)), and globular proteins (β-lactoglobulin, ovalbumin). We have observed that the addition of albumins leads to a significant increase in dyes fluorescence intensity. However, the fluorescent response of dyes in the presence of other globular proteins was notably lower. The value of fluorescence qua
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Rozovsky, Alex, Leonid Patsenker, and Gary Gellerman. "Bifunctional reactive pentamethine cyanine dyes for biomedical applications." Dyes and Pigments 162 (March 2019): 18–25. http://dx.doi.org/10.1016/j.dyepig.2018.09.064.

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Lange, Natalia, Wojciech Szlasa, Jolanta Saczko, and Agnieszka Chwiłkowska. "Potential of Cyanine Derived Dyes in Photodynamic Therapy." Pharmaceutics 13, no. 6 (2021): 818. http://dx.doi.org/10.3390/pharmaceutics13060818.

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Photodynamic therapy (PDT) is a method of cancer treatment that leads to the disintegration of cancer cells and has developed significantly in recent years. The clinically used photosensitizers are primarily porphyrin, which absorbs light in the red spectrum and their absorbance maxima are relatively short. This review presents group of compounds and their derivatives that are considered to be potential photosensitizers in PDT. Cyanine dyes are compounds that typically absorb light in the visible to near-infrared-I (NIR-I) spectrum range (750–900 nm). This meta-analysis comprises the current s
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Ndaleh, David, Cameron Smith, Mahesh Loku Yaddehige, et al. "Shortwave Infrared Absorptive and Emissive Pentamethine-Bridged Indolizine Cyanine Dyes." Journal of Organic Chemistry 86, no. 21 (2021): 15376–86. http://dx.doi.org/10.1021/acs.joc.1c01908.

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Mehranpour, Abdolmohammad, Sedigheh Hashemnia, Fereshteh Azamifar, and Elham Bashiri. "Synthesis and Characterization of New Quinoline Bounded Pentamethine Cyanine Dyes." Organic Preparations and Procedures International 52, no. 5 (2020): 458–62. http://dx.doi.org/10.1080/00304948.2020.1780881.

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Mehranpour, A. M., S. Hashemnia та R. Maghamifar. "Synthesis and Characterization of New γ-Substituted Pentamethine Cyanine Dyes". Synthetic Communications 40, № 24 (2010): 3594–602. http://dx.doi.org/10.1080/00397910903457290.

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Dissertations / Theses on the topic "Pentamethine cyanine dyes"

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Paranjpe, Shirish. "Synthesis of Novel Fluorescent Benzothiazole Cyanine Dyes as Potential Imaging Agents." Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/chemistry_theses/55.

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Near-infrared (NIR) fluorescence imaging has emerged as an attractive non-invasive approach for direct visualization of diseases which depends on the development of stable, highly specific and sensitive optical probes. The NIR region of the electronic spectrum offers a reduction in the background autofluorescence and an increase in the tissue penetration depth. Cyanine dyes have often been considered promising contrast optic agents owing to their photophysical properties. Herein the synthesis of various penta- and heptamethine benzothiazole cyanine dyes has been described and their in vivo ima
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Dost, Tyler L. "Synthesis and Determination of Optical Properties of Selected Pentamethine Carbocyanine Dyes." 2016. http://scholarworks.gsu.edu/chemistry_theses/90.

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This thesis begins with a brief review about the role and importance of the small molecules containing fluorine atoms in medicine and imaging. Then, the first part of the thesis will discuss the synthesis, purification and characterization of pentamethine cyanine dyes. The structure identification of the final dyes is done by using 1H NMR, 13C NMR, 19F NMR, and mass spectrometry. The studies performed after full characterization were the determination of optical and physicochemical properties. After these properties were performed, the fluorophores were evaluated to be good candidates for in v
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Kiernan, Kaitlyn. "Investigation and Characterization of Novel Pentamethine Cyanine Dyes for Use as Photosensitizers in Photodynamic Therapy." 2017. http://scholarworks.gsu.edu/chemistry_theses/98.

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Cyanine dyes that absorb light in the near infrared to far red region of the electromagnetic spectrum are desirable as photosensitizers for photodynamic cancer therapy. Light of wavelengths in this range is able to deeply penetrate tissue allowing for practical in vivo use of these dyes. A series of three structurally similar pentamethine cyanine dyes that absorb light ~800 nm to ~500 nm was tested to determine the effects of structural influences on the yields of supercoiled DNA photo-converted to nicked or linear forms. Possible mechanisms and optimal parameters for near- quantitative DNA ph
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