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Journal articles on the topic 'Pentosanpolysulfat'

Author: Grafiati

Published: 4 June 2021

Last updated: 11 February 2022

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1

Bublak, Robert. "Pentosanpolysulfat gegen interstitielle Zystitis." Uro-News 23, no. 7-8 (July 2019): 49. http://dx.doi.org/10.1007/s00092-019-2316-9.

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2

Harenberg, J., and R. Malsch. "Eigenschaften und Analytik von Heparinoiden." Hämostaseologie 16, no. 01 (January 1996): 1–5. http://dx.doi.org/10.1055/s-0038-1656631.

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ZusammenfassungHeparinoide umfassen strukturell und pharmakologisch unterschiedliche Substanzen mit Glykanstruktur. Als wichtigste Vertreter dieser Substanzklasse sind Dermatansulfat, Pentosanpolysulfat, Aprosulat und Orgaran anzusehen. In dieser Übersicht werden die chemische Struktur, die pharmakologischen Wirkungen dieser Stoffe und ihre Analytik besprochen. Sie wirken unterschiedlich auf die Gerinnungskaskade ein und inhibieren Thrombin. Zu ihrem Vergleich sind daher globale Gerinnungsteste notwendig. Ihre genaue pharmakologische Wirkung läßt sich durch spezifische Testsysteme bestimmen. Die chemische Bestimmung ihrer Struktur und Masse erfolgt über Elementaranalyse, spektroskopische, chromatographische und elektrophoretische Methoden.

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3

Kiöcking, H. P. "Pharmakologische Beeinflussung der Freisetzung von t-PA aus dem Gefäßendothel." Hämostaseologie 11, no. 02 (April 1991): 76–88. http://dx.doi.org/10.1055/s-0038-1660284.

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ZusammenfassungDie akute Freisetzung von tissue-type Plasminogenaktivator (t-PA) aus dem Gefäßendothel hat eine entscheidende Bedeutung für die Verhütung intravasaler Fibrinablagerungen.Mediatoren (plättchenaktivierender Faktor, Bradykinin, Histamin), adrenerge und cholinerge Transmitter (Isoprenalin, Acetylcholin), Gerinnungsfaktoren (Thrombin, Faktor Xa), polyanionische Verbindungen (Heparin, Pentosanpolysulfat, Natriumhumat, Enoxaparin-Natrium, Defibrotide), aliphatische Alkohole (Methanol, Ethanol, Propanol, Butanol) und 1-Desamino-8-D-argininvasopressin (DDAVP) bewirken am isoliert durchströmten Gefäßpräparat (Schweineohr) eine dosisabhängige t-PA-Freisetzung. Auch im Tierexperiment (Ratte, Kaninchen, Minischwein) kann eine Erhöhung der t-PA-Aktivität mit den meisten Verbindungen erreicht werden. Die t-PA-freisetzende Wirkung von DDAVP hat für diagnostische Zwecke Eingang in die Praxis gefunden. Eine pharmakologische Stimulierung der t-PA-Freisetzung könnte zur kurzzeitigen Thromboseprophylaxe und zur partiellen Thrombolyse genutzt werden. Dazu wären gegenwärtig nur Antithrombotika in der Lage, deren t-PA-Freisetzung erwiesen ist.

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4

Kiefer, H., D. Preiss, L. Heidrich, F. Mohr, and A. Petry. "Pentosanpolysulfat (SP 54®) - Alternative Gerinnungshemmung bei Heparinallergie während Operationen mit extrakorporaler Zirkulation." AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie 35, no. 01 (April 28, 2004): 1–2. http://dx.doi.org/10.1055/s-2000-10846-17.

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5

Johann, Sabine, Christine Zoller, Sylvia Haas, Günther Blümel, Martin Lipp, and Reinhold Förster. "Sulfated Polysaccharide Anticoagulants Suppress Natural Killer Cell Activity In Vitro." Thrombosis and Haemostasis 74, no. 04 (1995): 0998–1002. http://dx.doi.org/10.1055/s-0038-1649868.

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SummaryIn contrast to the well studied anticoagulant activity of sulfated polysaccharides (SPS), little is known about their influence on immune competent cells. Using two naturally derived SPSs (unfractionated heparin and low molecular weight heparin), one semi-synthetic SPS (pentosanpolysulfate), and one synthetic SPS (lactobionic acid) as well as the polypeptide hirudin we investigated the effect of these drugs on natural killer cell activity in vitro. We demonstrate that all SPSs tested significantly suppress the activity of natural killer cells at clinically relevant dosages. At all concentrations and at all effector:target ratios tested pentosanpolysulfate was the most potent natural killer cell inhibitor. In contrast, hirudin had no effect on natural killer cell function. Furthermore, scanning electron microscopy revealed that reduced natural killer cell activity is paralleled by decreased lymphocyte cell size and altered cell surface structures. Our results indicate that defined therapeutically applied SPSs can interfere with the tumor cell killing process.

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6

ZUPKAS, PAUL, C. LOWELL PARSONS, CANDICE PERCIVAL, and MANOJ MONGA. "Pentosanpolysulfate Coating of Silicone Reduces Encrustation." Journal of Endourology 14, no. 6 (August 2000): 483–88. http://dx.doi.org/10.1089/end.2000.14.483.

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7

Parsons, C. Lowell, and S. Grant Mulholland. "Successful Therapy of Interstitial Cystitis with Pentosanpolysulfate." Journal of Urology 138, no. 3 (September 1987): 513–16. http://dx.doi.org/10.1016/s0022-5347(17)43243-5.

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8

Kalota, Susan Jones, Paul C. Stein, and C. Lowell Parsons. "Prevention of Acrolein-Induced Bladder Injury by Pentosanpolysulfate." Journal of Urology 148, no. 1 (July 1992): 163–66. http://dx.doi.org/10.1016/s0022-5347(17)36545-x.

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9

Jepsen, Jan V., Mogens Sall, Patsy R. Rhodes, Diane Schmidt, Edward Messing, and Reginald C. Bruskewitz. "Long-term experience with pentosanpolysulfate in interstitial cystitis." Urology 51, no. 3 (March 1998): 381–87. http://dx.doi.org/10.1016/s0090-4295(97)00714-0.

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10

Parsons, C. L. "Sodium Pentosanpolysulfate Treatment of Interstitial Cystitis: An Update." Journal of Urology 138, no. 4 Part 1 (October 1987): 920. http://dx.doi.org/10.1016/s0022-5347(17)43421-5.

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11

Parsons, C. Lowell. "Successful Management of Radiation Cystitis with Sodium Pentosanpolysulfate." Journal of Urology 136, no. 4 (October 1986): 813–14. http://dx.doi.org/10.1016/s0022-5347(17)45087-7.

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12

Jepsen, J. V., M. Sall, P. R. Rhodes, D. Schmidt, E. Messing, and R. C. Bruskewitz. "Long-Term Experience With Pentosanpolysulfate in Interstitial Cystitis." Journal of Urology 160, no. 3 Part 1 (September 1998): 963. http://dx.doi.org/10.1016/s0022-5347(01)62870-2.

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13

Callahan, Hugh J., Dolores Shupp-Byrne, Melina Pizzo, C. Lowell Parsons, and S. Grant Mulholland. "The production of antibodies to pentosanpolysulfate (ELMIRON, SP-54)." Journal of Immunological Methods 136, no. 1 (January 1991): 53–59. http://dx.doi.org/10.1016/0022-1759(91)90249-f.

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14

Krupinski, K., H. K. Breddin, and B. Casu. "Anticoagulant and Antithrombotic Effects of Chemically Modified Heparins and Pentosanpolysulfate." Pathophysiology of Haemostasis and Thrombosis 20, no. 2 (1990): 81–92. http://dx.doi.org/10.1159/000216112.

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15

Hunzelmann, Nicolas, Hermann Gold, and Karin Scharffetter-Kochanek. "Concomitant sensitization to high and low molecular-weight heparins, heparinoid and pentosanpolysulfate." Contact Dermatitis 39, no. 2 (August 1998): 88–89. http://dx.doi.org/10.1111/j.1600-0536.1998.tb05845.x.

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16

Fritjofsson, Å., M. Fall, R. Juhlin, B. E. Persson, and M. Ruutu. "Treatment of Ulcer and Nonulcer Interstitial Cystitis with Sodium Pentosanpolysulfate: A Multicenter Trial." Journal of Urology 138, no. 3 (September 1987): 508–12. http://dx.doi.org/10.1016/s0022-5347(17)43242-3.

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17

Pilepich, Miljenko V., R. Paulus, William St. Clair, Ralph A. Brasacchio, Robert Rostock, and Robert C. Miller. "Phase III Study of Pentosanpolysulfate (PPS) in Treatment of Gastrointestinal Tract Sequelae of Radiotherapy." American Journal of Clinical Oncology 29, no. 2 (April 2006): 132–37. http://dx.doi.org/10.1097/01.coc.0000203758.77490.fd.

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18

Parsons, C. Lowell, George Benson, Stacy J. Childs, Philip Hanno, Grannum R. Sant, and George Webster. "A Quantitatively Controlled Method to Study Prospectively Interstitial Cystitis and Demonstrate the Efficacy of Pentosanpolysulfate." Journal of Urology 150, no. 3 (September 1993): 845–48. http://dx.doi.org/10.1016/s0022-5347(17)35629-x.

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19

Shkumatov, V. M., Yu A. Lesnikovich, E. A. Chernayvskii, and D. L. Yanovich. "A Comparative Analysis of the Formation of Complexes of Pentosanpolysulfate and Heparin with Various Proteins." Pharmaceutical Chemistry Journal 37, no. 9 (September 2003): 499–503. http://dx.doi.org/10.1023/b:phac.0000008253.82715.e0.

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20

Giedrojc, J., and H. K. Breddin. "Anticoagulant and antithrombotic actions of natrium- and calcium-pentosanpolysulfate in an experimental thrombosis rat model." Thrombosis Research 65 (January 1992): S156. http://dx.doi.org/10.1016/0049-3848(92)90625-k.

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21

Kiesel, J., G. Harbauer, E. Wenzel, G. Pindur, and St Bohnerth. "Comparison of the effects of sodium pentosanpolysulfate and unfractionated heparin on venous thrombosis; an experimental study in rats." Thrombosis Research 64, no. 3 (November 1991): 301–8. http://dx.doi.org/10.1016/0049-3848(91)90001-d.

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22

Grigsby, Perry W., Miljenko V. Pilepich, and C. Lowell Parsons. "Preliminary Results of a Phase I/II Study of Sodium Pentosanpolysulfate in the Treatment of Chronic Radiation-Induced Proctitis." American Journal of Clinical Oncology 13, no. 1 (February 1990): 28–31. http://dx.doi.org/10.1097/00000421-199002000-00008.

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23

Daha, Lukas K., Dara Lazar, Reiner Simak, and Heinz Pflüger. "The effects of intravesical pentosanpolysulfate treatment on the symptoms of patients with bladder pain syndrome/interstitial cystitis: preliminary results." International Urogynecology Journal 19, no. 7 (January 29, 2008): 987–90. http://dx.doi.org/10.1007/s00192-008-0560-8.

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24

CHIANG, GEORGE, PHANI PATRA, RICHARD LETOURNEAU, SHEILA JEUDY, WILLIAM BOUCHER, MARLON GREEN, GRANNUM R. SANT, and THEOHARIS C. THEOHARIDES. "PENTOSANPOLYSULFATE INHIBITS MAST CELL HISTAMINE SECRETION AND INTRACELLULAR CALCIUM ION LEVELS:: AN ALTERNATIVE EXPLANATION OF ITS BENEFICIAL EFFECT IN INTERSTITIAL CYSTITIS." Journal of Urology 164, no. 6 (December 2000): 2119–25. http://dx.doi.org/10.1016/s0022-5347(05)66981-9.

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25

Holm-Bentzen, Merete, Flemming Jacobsen, Benni Nerstrøm, Gunnar Lose, Jørgen Kvist Kristensen, René Hald Pedersen, Torben Krarup, et al. "A Prospective Double-Blind Clinically Controlled Multicenter Trial of Sodium Pentosanpolysulfate in the Treatment of Interstitial Cystitis and Related Painful Bladder Disease." Journal of Urology 138, no. 3 (September 1987): 503–7. http://dx.doi.org/10.1016/s0022-5347(17)43241-1.

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26

"Neuzulassung: Pentosanpolysulfat gegen Blasenschmerzsyndrom." Uro-News 21, no. 12 (November 28, 2017): 67. http://dx.doi.org/10.1007/s00092-017-1721-1.

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27

"Interstitielle Zystitis - Pentosanpolysulfat und Heparin verbessern Allgemeinbefinden und Symptomatik." Aktuelle Urologie 37, no. 5 (September 2006): 316–20. http://dx.doi.org/10.1055/s-2006-951426.

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28

Jepsen, J. V., M. Sall, P. R. Rhodes, D. Schmidt, E. Messing, and R. C. Bruskewitz. "Long-Term Experience With Pentosanpolysulfate in Interstitial Cystitis." Journal of Urology, September 1998, 963. http://dx.doi.org/10.1097/00005392-199809010-00126.

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29

CHIANG, GEORGE, PHANI PATRA, RICHARD LETOURNEAU, SHEILA JEUDY, WILLIAM BOUCHER, MARLON GREEN, GRANNUM R. SANT, and THEOHARIS C. THEOHARIDES. "PENTOSANPOLYSULFATE INHIBITS MAST CELL HISTAMINE SECRETION AND INTRACELLULAR CALCIUM ION LEVELS:." Journal of Urology, December 2000, 2119–25. http://dx.doi.org/10.1097/00005392-200012000-00075.

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