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Dissertations / Theses on the topic 'Pentraxina 3'

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Published: 4 June 2021

Last updated: 11 March 2023

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1

Gifoni, Markus Andret Cavalcante. "Envolvimento da pentraxina 3 (PTX3) na patogÃnese da cistite hemorrÃgica induzida por ifosfamida em camundongos." Universidade Federal do CearÃ, 2008. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=1245.

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CoordenaÃÃo de AperfeiÃoamento de Pessoal de NÃvel Superior<br>A cistite hemorrÃgica (CH) Ã um fenÃmeno inflamatÃrio frequentemente associado Ã quimioterapia com oxazafosforinas. Trata-se de uma resposta inflamatÃria inata Ã aÃÃo da AcroleÃna (ACR), metabÃlito hepÃtico comum Ã Ifosfamida (IFO) e Ã ciclofosfamida (CTX). O papel da resposta ao recrutamento de receptores toll-like (TLR) e do estÃmulo por TNF-α e IL-1β com envolvimentto de iNOS e COX-2 tem sido demonstrado neste fenÃmeno. Estudos recentes demonstram que a Pentraxina 3 (PTX3) assume papel de mediador inflamatÃrio em model

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Rodrigues, Priscila Fabiana. "Avaliação do efeito da proteína Pentraxina 3 em células tumorais murinas." Universidade Federal de Minas Gerais, 2014. http://hdl.handle.net/1843/BUOS-9MKKQ3.

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Pentraxin 3 (PTX3) is an inflammatory protein that plays important role in innate immunity, matrix deposition and female fertility. Moreover, it is a natural antagonist of fibroblast growth factor 2 (FGF2) that inhibit the cellular proliferation and angiogenesis promoted by this factor. PTX3 binds to FGF2 in the site of interaction with its receptor (FGFR) preventing the activation of FGF2/FGFR signaling pathway and, as a consequence, inhibiting the expression of genes related to cell proliferation, migration, differentiation, survival and angiogenesis. Neoplasms are among the leading causes o

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3

Carizzo, Albino. "La Pentraxina 3: un potenziale marcatore di danno endoteliale nell’ipertensione arteriosa." Doctoral thesis, Universita degli studi di Salerno, 2016. http://hdl.handle.net/10556/2195.

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2014 - 2015<br>Background - The pentraxin 3 (PTX3) is a protein of the acute phase of inflammation which represents the prototype of the long pentraxins. In the last years, numerous studies have correlated the elevated plasma levels of PTX3 with cardio- and cerebrovascular diseases and recently with high blood pressure. To date, there are no studies showing whether PTX3 is able to exert a direct action on the vascular component. Methods and Results - Through in vitro experiments of vascular reactivity and ultrastructural analysis, we have shown that PTX3 induces, per se, dysfunction and

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SCARCHILLI, LAURA. "Caratterizzazione e interazione di pentraxina 3 e inter -alpha-trypsin-inhibitor nella matrice del cumulo ooforo." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2006. http://hdl.handle.net/2108/208526.

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E' stato precedentemente dimostrato che la sintesi di PTX3 è stimolata nelle cellule del cumulo durante il periodo preovulatorio ed è essenziale per l'organizzazione dell'acido ialuronico e l'espansione del complesso ovocito-cellule del cumulo (COC). Il presente studio mostra che, sebbene tumor necrosis factor α and interleukin-1β siano capaci di indurre PTX3 in molti tipi cellulari e sebbene queste citochine siano prodotte nel follicolo, la prima non ha nessun effetto sulla sintesi di PTX3 e sull'espansione di COC coltivati in vitro e la seconda è soltanto parzialmente efficace, suggere

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Nunes, João Paulo Silva. "Avaliação do efeito biológico da pentraxina 3 em linhagens de células tumorais humanas." Universidade Federal de Minas Gerais, 2014. http://hdl.handle.net/1843/BUOS-9KWJP6.

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The pentraxin 3 is an acute phase glycoprotein expressed in a wide variety of cells and plays a myriad of roles in biological processes including female fertility, innate immunity and angiogenesis. PTX3 interacts selectively and specifically to fibroblast growth factors (FGFs) preventing the engagement of these factors with their specific tyrosine kinase receptors (FGFRs). The FGF/FGFR system plays important roles in many processes such as migration, differentiation, survival and cell proliferation, and in angiogenesis. Angiogenesis contributes to the development and progression of a variety o

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6

Vietta, Giovanna Grünewald. "Caracterização dos níveis da pentraxina-3 (PTX-3) em amostra de pacientes com cardiopatia isquêmica estável na população brasileira." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2008. http://hdl.handle.net/10183/17435.

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Introdução: A Pentraxina-3 (PTX-3), produzida principalmente por macrófagos e células da vasculatura endotelial em resposta aos primeiros sinais pró-inflamatórios, tem sido apontada como um novo marcador de eventos coronarianos. Este estudo objetiva caracterizar os níveis plasmáticos de PTX-3 em pacientes com doença arterial coronariana estável em uma população brasileira, bem como sua relação com outros marcadores de risco cardiovascular e manifestação clínica de doença arterial coronariana (DAC). Métodos: Caracterização dos fatores de risco cardiovascular clássicos, e determinação dos níveis

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7

Gifoni, Markus Andret Cavalcante. "Envolvimento da pentraxina 3 (PTX3) na patogênese da cistite hemorrágica induzida por ifosfamida em camundongos." reponame:Repositório Institucional da UFC, 2008. http://www.repositorio.ufc.br/handle/riufc/2592.

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GIFONI, Markus Andret Cavalcante. Envolvimento da pentraxina 3 (PTX3) na patogênese da cistite hemorrágica induzida por ifosfamida em camundongos. 130 f. 2008. Dissertação (Mestrado em Farmacologia) - Universidade Federal do Ceará. Faculdade de Medicina, Fortaleza, 2008.<br>Submitted by denise santos (denise.santos@ufc.br) on 2012-05-04T16:36:22Z No. of bitstreams: 1 2008_dis_macgifoni.pdf: 3631477 bytes, checksum: 2a13693f0c54b428c60eea4f01db4b4f (MD5)<br>Approved for entry into archive by Eliene Nascimento(elienegvn@hotmail.com) on 2012-05-08T16:54:05Z (GMT) No. of bitstreams: 1 2008_dis_mac

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Cozzi, V. "Pentraxina 3 come potenziale marcatore di danno endoteliale in gravidanze complicate da preeclampsia e ritardato accrescimento intrauterino." Doctoral thesis, Università degli Studi di Milano, 2012. http://hdl.handle.net/2434/174026.

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Objectives: Endothelial dysfunction typical of preeeclampsia (PE) is the result of an excessive maternal inflammatory response to pregnancy. PE can occur alone or together with intrauterine growth restriction (IUGR). We investigated PTX3 in maternal, fetal and placental compartments in complicated pregnancies. Study design: Maternal blood samples were collected during the III trimester in 53 PE, 43 IUGR and 50 normal pregnancies. Fetal samples were collected from the umbilical vein in 26 PE, 23 IUGR and 26 normal pregnancies at elective cesarean section. PTX3 plasma levels were determined by

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9

Junqueira, Ana FlÃvia Torquato de AraÃjo. "Estudo do efeito do inibidor da enzima adenosina desaminase, EHNA, sobre a enterite induzida pela toxina a do Clostridium difficile em alÃa ileal isolada de camundongos." Universidade Federal do CearÃ, 2008. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=1305.

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Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgico<br>O Clostridium difficile tem como principal fator de virulÃncia a toxina A (TxA), a qual provoca inflamaÃÃo e destruiÃÃo tecidual aguda em intestinos de animais experimentais e de pacientes com a doenÃa induzida por esta bactÃria. Em locais de injÃria tecidual, adenosina Ã produzida em altas concentraÃÃes, onde exerce uma sÃrie de efeitos antiinflamatÃrios, limitados por sua rÃpida degradaÃÃo pela enzima adenosina desaminase. O objetivo deste trabalho foi investigar o efeito da inibiÃÃo da enzima adenosina desaminase pelo EHNA (er

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Gullo, Jackson da Silva. "Associação entre os níveis séricos de pentraxina 3 e a mortalidade de pacientes vítimas de traumatismo crânio-encefálico grave." reponame:Repositório Institucional da UFSC, 2013. http://repositorio.ufsc.br/handle/123456789/103292.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Ciências Médicas, Florianópolis, 2010<br>Made available in DSpace on 2013-07-16T04:02:21Z (GMT). No. of bitstreams: 1 276711.pdf: 1258846 bytes, checksum: 74a809fae7fb12b98d0bba9fc2970e03 (MD5)<br>Introdução: O trauma cranioencefálico (TCE), é a umas das maiores causas de morbidade e mortalidade no mundo. Pentraxina 3 (PTX3) é um componente do sistema humoral de resposta imune inata que tem sido estudada como marcador para inflamação, infecções ou patologias cardiovascular

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Martin, Laura Fernandes [UNESP]. "Expressão de Pentraxina 3 no líquido amniótico e imunolocalização nas membranas corioamníóticas de gestações de termo e complicadas por parto pré-termo." Universidade Estadual Paulista (UNESP), 2013. http://hdl.handle.net/11449/108487.

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Made available in DSpace on 2014-08-13T14:50:40Z (GMT). No. of bitstreams: 0 Previous issue date: 2013Bitstream added on 2014-08-13T18:01:28Z : No. of bitstreams: 1 000747189.pdf: 1571276 bytes, checksum: cb0e6f84e4a758217e41fa9ef75dba98 (MD5)<br>Changes in the Pentraxin 3 (PTX3) expression throughout pregnancy are not well established but in pregnancy complications higher expression have been described. To evaluate expression of PTX3 in amniotic fluid (AF) throughout the last weeks of normal pregnancies and in pregnancies complicated by preterm delivery (PTD). A crosssectional study was con

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Martin, Laura Fernandes. "Expressão de Pentraxina 3 no líquido amniótico e imunolocalização nas membranas corioamníóticas de gestações de termo e complicadas por parto pré-termo /." Botucatu, 2013. http://hdl.handle.net/11449/108487.

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Orientador: Márcia Guimarães da Silva<br>Coorientador: Rodrigo Paupério Soares de Camargo<br>Banca: Gisele Alborghetti Nai<br>Banca: Denise Fecchio<br>Resumo: Não disponível<br>Abstract: Changes in the Pentraxin 3 (PTX3) expression throughout pregnancy are not well established but in pregnancy complications higher expression have been described. To evaluate expression of PTX3 in amniotic fluid (AF) throughout the last weeks of normal pregnancies and in pregnancies complicated by preterm delivery (PTD). A crosssectional study was conducted with 120 pregnant women in term and PTD. Samples of AF

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Bonacina, F. "ROLE OF THE LONG PENTRAXIN 3 (PTX3) IN CARDIOMETABOLIC DISEASES." Doctoral thesis, Università degli Studi di Milano, 2016. http://hdl.handle.net/2434/353808.

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PTX3 is a biomarker of cardiovascular diseases and exerts protective functions in acute myocardial infarction and atherosclerosis. Here we aimed at investigating the role of PTX3 in cardiovascular diseases. First we studied the role of PTX3 in arterial thrombosis induced by FeCl3 injury: PTX3 KO mice showed a 60% reduction in carotid artery blood flow with a greater thrombus formation compared to 20% of WT mice (p<0.01) following arterial thrombosis, an effect mediated by PTX3 derived from non-hematopoietic cells: indeed, PTX3 KO mice transplanted with bone marrow from WT or PTX3 KO mice pres

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Flatscher, Katharina. "Stellenwert von Pentraxin-3 als diagnostischer Marker für die Prädiktion der Präeklampsie." Diss., Ludwig-Maximilians-Universität München, 2014. http://nbn-resolving.de/urn:nbn:de:bvb:19-170954.

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CHURRUCA, SCHUIND ANDER. "The Long Pentraxin 3 contributes to triple negative breast cancer stemness tumorigenicity." Doctoral thesis, Università degli studi di Brescia, 2021. http://hdl.handle.net/11379/554943.

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Marschner, Julian [Verfasser], and Hans-Joachim [Akademischer Betreuer] Anders. "Die Rolle von Pentraxin 3 bei entzündlichen Nierenerkrankungen / Julian Marschner ; Betreuer: Hans-Joachim Anders." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2019. http://d-nb.info/1193048931/34.

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Maina, V. "Pentraxin 3 : a multifunctional soluble pattern recognition receptor involved in inflammation and tissue remodelling." Doctoral thesis, Università degli Studi di Milano, 2009. http://hdl.handle.net/2434/64587.

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MOREGOLA, ANNALISA. "THE LONG PENTRAXIN 3 PLAYS A KEY ROLE IN THE IMMUNOMODULATION OF DIET-INDUCED OBESITY." Doctoral thesis, Università degli Studi di Milano, 2018. http://hdl.handle.net/2434/605984.

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The long pentraxin 3 plays a key role in the immunomodulation of diet-induced obesity AIM: Obesity is characterized by a state of chronic low-grade inflammation. PTX3 is the prototype of long pentraxins, it is an essential component of the humoral arm of innate immunity and is involved in many inflammatory processes. There are several conflicting data about the role of PTX3 in obesity. Aim of this project was to clarify whether PTX3 behaves as a bystander or actively participates to obesity-related inflammation. METHODS: PTX3 KO and WT littermates were fed a high fat diet (HFD; 45% Kcal fro

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Becker, Christopher A. [Verfasser]. "Die Rolle von Pentraxin 3 und Interleukin-6-Transsignaling im Rahmen des Polytraumas / Christopher A. Becker." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2015. http://d-nb.info/1079524711/34.

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Flatscher, Katharina [Verfasser], and Katrin [Akademischer Betreuer] Karl. "Stellenwert von Pentraxin-3 als diagnostischer Marker für die Prädiktion der Präeklampsie / Katharina Flatscher. Betreuer: Katrin Karl." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2014. http://d-nb.info/1053913710/34.

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Slusher, Aaron L. "COUNTERREGULATORY EFFECTS OF PTX3 ON INFLAMMATION AND CELLULAR AGING." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5287.

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Pentraxin 3 (PTX3) is a vital regulator of innate immune function that has been shown to counterregulate pro-inflammatory signaling and protect against the development of cardiovascular disease (CVD). Less is known about how PTX3 may mitigate against CVD risk by regulating the pro-inflammatory response at the cellular level. Therefore, this dissertation details four manuscripts which aimed to examine the capacity of PTX3 to regulate the innate immune response of peripheral blood mononuclear cells (PBMCs) isolated from healthy adults. Manuscript 1 examined the capacity of PTX3 to alter the infl

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Böhme, Michael Hjalmar Axel [Verfasser]. "Assoziationen von Pentraxin 3 und anderen inflammatorischen Markern mit Restnierenfunktion, Nierenersatztherapiedauer und kardiovaskulären Erkrankungen bei Dialysepatienten / Michael Hjalmar Axel Böhme." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2011. http://d-nb.info/1025354389/34.

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Cotena, A. "The long pentraxin 3 : a key component of innate immunity, modulates the inflammatory response to non self and self ligands." Doctoral thesis, Università degli Studi di Milano, 2009. http://hdl.handle.net/2434/64593.

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Hamon, Yveline. "Mise en évidence d'une altération fonctionnelle du récepteur soluble de l'immunité innée PTX3 dans la mucoviscidose." Phd thesis, Université d'Angers, 2013. http://tel.archives-ouvertes.fr/tel-00843818.

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La pentraxine longue PTX3, récepteur soluble de l'immunité innée, joue un rôle important dans la protection contre certains pathogènes, en favorisant leur élimination et l'initiation de réponses immunitaires protectrices. PTX3 a notamment un rôle protecteur lors d'infections par Aspergillus fumigatus et Pseudomonas aeruginosa. La mucoviscidose, maladie héréditaire grave à transmission autosomique récessive, est caractérisée par des infections pulmonaires récurrentes, notamment par ces deux pathogènes. Nous avons donc émis l'hypothèse que le statut de PTX3 pourrait être altéré chez ces patients

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LAROSA, MADDALENA. "THE ROLE OF PENTRAXIN-3 AS PREDICTOR OF PREGNANCY COMPLICATIONS IN PATIENTS WITH SLE AND/OR ANTI-PHOSPHOLIPID SYNDROME AND APL CARRIERS." Doctoral thesis, Università degli studi di Padova, 2022. http://hdl.handle.net/11577/3459228.

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Systemic Lupus Erythematosus (SLE) is an autoimmune disease affecting childbearing women. Nowadays, mainly due to preconception counselling, the overall prognosis of such pregnancies has consistently improved. Preconception visit is pivotal to assess anti-phospholipid (aPL) antibodies and/or anti-phospholipid syndrome (APS), drugs’ safety and disease activity, in order to prevent adverse pregnancy outcomes (APOs) and maternal flares. The general aim of the thesis was to improve the management of pregnant SLE and/or APS patients by assessing pregnancy outcomes and identifying predictors of APOs

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Göbel, Jens [Verfasser], Giuliano [Akademischer Betreuer] Ramadori, Michael [Akademischer Betreuer] Oellerich, and Thomas [Akademischer Betreuer] Lorf. "Bestimmung von Pentraxin-3 im Blutserum und dessen Bedeutung für Lebererkrankungen / Jens Göbel. Gutachter: Giuliano Ramadori ; Michael Oellerich ; Thomas Lorf. Betreuer: Giuliano Ramadori." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2013. http://d-nb.info/1044173262/34.

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Palm, Maria. "Oxidative Stress, Angiogenesis and Inflammation in Normal Pregnancy and Postpartum." Doctoral thesis, Uppsala universitet, Institutionen för kvinnors och barns hälsa, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-171165.

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The aims were to investigate oxidative stress (I), angiogenesis (II) and inflammation (III-IV) in healthy women during pregnancy and postpartum. Oxidative stress was estimated by measurement of 8-iso-PGF2α and the antioxidants α- and γ-tocopherol. The angiogenic factors PlGF, VEGF-A and the antiangiogenic factor sFlt1 were measured to estimate angiogenesis. PTX3, IL-6, TNF-α and a PGF2α metabolite were measured to estimate inflammation. Out of 52 included women, 15 had minor pregnancy complications and 37 were classified as normal. In study III data from all 52 women were used. For the other s

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Jaillon, Sébastien. "Nouveaux sites d'expression et rôles fonctionnels de Pentracine 3, récepteur soluble de l'immunité innée." Angers, 2007. http://www.theses.fr/2007ANGE0064.

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Le système immunitaire est constitué de deux composantes : l'immunité innée et l'immunité adaptative. Alors que le système immunitaire adaptatif utilise des récepteurs spécifiques pour la reconnaissance des antigènes, les récepteurs utilisés par l'immunité innée sont appelés « Pattern Recognition Receptors 1 » ou PPR. Les PRRs reconnaissent des motifs hautement conservés durant l'évolution, exprimés exclusivement par les microorganismes et appelés « Pathogen Associated Molecular Pattern » ou PAMP. Les PRRs sont composés des PRRs associés aux cellules (impliqués dans l'endocytose et/ou la signa

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Yenuga, Hima Priya. "Characterization of proteins found in serum and sputum samples from ventilator associated pneumonia patients." Wright State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=wright1590233445157576.

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"Pentraxin 3 in the lung and neutrophils." Thesis, 2013. http://hdl.handle.net/10388/ETD-2013-08-1195.

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Respiratory diseases are a major cause of human morbidity and mortality and are a leading cause of economic loss to livestock producers. The respiratory tract is constantly in contact with dust, bacteria, fungi, viruses and other pathogenic agents that are found in the air. Normally, the body has the ability to clear these foreign particles. However, physiological and environmental stresses can impair airway defense mechanisms resulting in establishment of pulmonary infections. The microbes and their products engage various receptors in the lung to activate epithelium, endothelium, macroph

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Chang, Wan-Ting, and 張睆婷. "The role of Pentraxin 3 in human cervical cancer cells." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/98416951269040909154.

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碩士<br>中山醫學大學<br>生化暨生物科技研究所<br>102<br>Cervical carcinoma is one of the most frequent cancers in women and is associated with high-risk human papilloma virus (HPV) infection. It causes many women death in Taiwan. PTX3 also called tumor necrosis factor-inducible protein 14 gene (TSG-14) were mapped to chromosomes 24q28.3. PTX3 regulate cell growth, differentiation, invasion and apoptosis have been reported. However, its involvement in human cervical cancer progression remains unclear. In our study, Using human cervical cancer tissues array, we found that expression level of PTX3 is higher in h

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Göbel, Jens. "Bestimmung von Pentraxin-3 im Blutserum und dessen Bedeutung für Lebererkrankungen." Doctoral thesis, 2013. http://hdl.handle.net/11858/00-1735-0000-000E-0135-C.

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Aufgabe dieser Arbeit war es, den Serumspiegel von Pentraxin-3-Werten im Blutplasma bei Lebererkrankungen zu bestimmen und mit anderen diagnostischen Parametern zu vergleichen. Vorausgegangene Studien hatten bereits darauf hingewiesen, dass PTX3-Werte als früh verfügbare und aussagekräftige Marker bei Entzündungskrankheiten in verschiedenen Organen hilfreich sein können. Es wurden zwei Patientenkollektive miteinander verglichen. Von 25 Patienten ohne Lebertransplantation und von 39 Patienten nach Lebertransplantation wurden die PTX3-Werte mit Hilfe des „Quantikine® Human Pentraxin 3/TSG-14 Im

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Chih-Chia and 張秩嘉. "Study of plasma Pentraxin 3 in patients with pelvic inflammatory disease." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/86414237513515508546.

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博士<br>中山醫學大學<br>醫學研究所<br>99<br>Pentraxin 3 (PTX3) plays an important role in innate immune responses and in inflammation disease. The aim of this study was to investigate the diagnostic and prognostic potential of PTX3 in pelvic inflammatory disease (PID) and correlate it with the severity and outcome of PID. In this study, we collected blood specimens from 64 patients with PID before and after treatment and 70 healthy controls and measured the plasma levels of PTX3 using enzyme-linked immunosorbent assay (ELISA) kits. We found that the plasma level of PTX3 expression was elevated in PID patie

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Holubcová, Zdeňka. "Dlouhý pentraxin 3 - prediktivní biomarker poškozující zánětové odpovědi u nemocných operovaných na srdci?" Doctoral thesis, 2017. http://www.nusl.cz/ntk/nusl-352799.

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(LONG PENTRAXIN 3 - A PUTATIVE BIOMARKER WITH PREDICTIVE VALUE TO IDENTIFY THE ADVERSE INFLAMMATORY RESPONSE IN CARDIAC SURGICAL PATIENTS?) INTRODUCTION. Cardiac surgery is well established for development of systemic inflammatory response. There are still no biomarkers with significant predictive value to identify patients at risk. AIM. The aim of this study was to compare the dynamics of pentraxin 3 (PTX3) and other inflammatory biomarkers (CRP, TLR2 and IL-8) after cardiac surgery with particular regards to different postoperative clinical manifestation of inflammatory response. Furthermore

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Hung, Tung-Wei, and 洪東衛. "Pentraxin 3 Activates JNK Signaling and Regulates the Epithelial-To-Mesenchymal Transition in Renal Fibrosis." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/3d5rx5.

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博士<br>中山醫學大學<br>醫學研究所<br>106<br>Objective：Tubulointerstitial fibrosis can lead to end-stage renal disease. Pentraxin 3 (PTX3) is an acute phase protein produced by resident and innate immunity cells. We investigated the effect of PTX3 on cultured human proximal tubular epithelial (HK-2) cells and a rat unilateral ureteral obstruction (UUO) model of renal fibrosis. Methods and Materials：Gain-of-function experiments were used to examine the effect of recombinant human PTX3 (Rh-PTX3) on HK-2 cells. Cell proliferation (MTT assay) and in vitro cell migration were measured. The levels of PTX3, p-JNK

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Mendes, Maria Silvina Marques. "Human fluids pretreatment using three-phase partitioning systems for the diagnosis and prognosis of lung cancer." Master's thesis, 2021. http://hdl.handle.net/10773/31941.

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Lung cancer is responsible for the highest rate of cancer mortality worldwide. The 5-year survival rate of lung cancer is less than 15%, mainly because most lung cancer patients are diagnosed at late stages. Therefore, early detection of lung cancer represents one of the most effective approaches to help reduce the high associated mortality and morbidity. Technological advances in genomics and proteomics fields have disclosed many novel cancer biomarkers, which can be used in early cancer detection. Pentraxin-3 is one of these promising biomarkers, found in serum, for lung cancer diagnosis and

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Yang-MingLiu and 劉揚民. "Purification and Crystallization Studies of Transcription Factor CCAAT/Enhancer Binding Protein delta and Inflammatory Factor Long Pentraxin 3." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/93061943844711154657.

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碩士<br>國立成功大學<br>生物資訊與訊息傳遞研究所<br>102<br>Abstract Part A: CEBPδ Transcription factor CEBPδ is involved in cell differentiation, motility, growth arrest, proliferation, and cell death. Studies also suggested that CEBPδ functions differed depending on cell type and cellular context. CEBPδ has been proved as a tumor suppressor in some cancers, for example, in breast cancer. But CEBPδ also help glioblastoma cell’s survival by inflammation response and induce metastasis. Previous studies had reported CEBPδ has many posttranslational modification sites and need to form a dimer with other family member

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Shuo-LunWu and 吳碩倫. "Transcriptional activation of pentraxin-3 gene expression is associated with EGF-induced head and neck cancer cell metastasis." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/53100809601694216208.

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碩士<br>國立成功大學<br>生物資訊與訊息傳遞研究所<br>102<br>SUMMARY Overexpression of epidermal growth factor receptor (EGFR) and production of proinflammatroy cytokines are well clarified in head and neck squamous cell carcinoma (HNSCC) and correlates with invasion and metastasis. However, molecular mechanisms by which EGFR-mediated cytokines regulates metastasis of HNSCC remain unclear. Here, we identified that PTX3 is a metastasis-promoting factor that mediate EGF-induced HNSCC metastasis. Analysis of PTX3 expression between normal and malignant or metastatic tissues from HNSCC patients by using published data

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Zickler, Daniel [Verfasser]. "Einfluss von C-reaktivem Protein und Pentraxin 3 auf die Kalzifikation glatter Muskelzellen und Zytokinproduktion von Monozyten im Prozess der Arteriosklerose / von Daniel Zickler." 2010. http://d-nb.info/1010399810/34.

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