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Journal articles on the topic 'Peptic stomach ulcer'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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1

Pilipenko, M. V. "Peptic ulcer." Spravočnik vrača obŝej praktiki (Journal of Family Medicine), no. 12 (November 30, 2023): 68–73. http://dx.doi.org/10.33920/med-10-2312-07.

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Peptic ulcer is a chronic relapsing disease that occurs with alternating periods of exacerbation and remission, the leading manifestation of which is the formation of a defect (ulcer) in the wall of the stomach and duodenum. It has been shown that 11-14% of men and 8-11% of women may develop peptic ulcer disease during their lifetime. Peptic ulcer localized in the duodenum occurs 4 times more frequently than peptic ulcer in the stomach. Among patients with duodenal ulcers, men predominate over women, while among patients with gastric ulcers, the ratio of men and women is approximately the same

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2

Yousif, Entisar Kuku, Howeida Abdullah Mustafa, and Alkhair Abd Almahmoud Idris. "An Experimental Study on the Healing Effect of Water to Traditional Sudanese Liquor (Aragi)-induced Stomach Peptic Ulcers." Molecular and Cellular Biomedical Sciences 6, no. 2 (2022): 85. http://dx.doi.org/10.21705/mcbs.v6i2.233.

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Background: Peptic ulcer is one of the most common gastrointestinal tract diseases which affect the stomach. This study aimed to determine the effect of aragi on the adult rats' stomach and investigate the effect of water as a therapeutic agent on aragi-induced ulcerations.Materials and methods: Thirty-five adult Wistar albino rats were used in this experimental study. Five rats were sacrificed on day 0, 5 rats were used as a control group, and 25 rats were treated with aragi. On day 15, all rats in the control group and five aragi-treated rats were sacrificed for histological examination of t

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3

Ndidi, Kelichi. "Gastric Ulcers; Causes, Symptoms, Treatment, and Prevention." Journal Wetenskap Health 1, no. 1 (2020): 1–4. http://dx.doi.org/10.48173/jwh.v1i1.8.

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The study discusses the cause, symptom, medication, and prevention of peptic ulcers. The discussion is the main cause of ulcer disease at this time is believed to be due to stomach infection by bacteria we called “Helicobacter pyloricus (H. pylori). the main clinical feature of peptic ulcers is chronic, intermittent epigastric pain which typically subsides after ingestion of food or antacids Some complain of burning in the upper stomach or painful hunger one to three hours after eating or at night when the stomach is empty. Smoking is also an important cause of ulcer formation and failure of u

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4

John Umaru, Isaac. "Peptic Ulcer Disease and Its Implications." Research of Gastric Management and Hepatology 1, no. 1 (2023): 01–04. http://dx.doi.org/10.58489/2836-6204/004.

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Peptic ulcer disease (PUD) is one of the commonest diseases seen throughout the world. Peptic ulcers are open sores that develop on the inside lining of your stomach and the upper portion of your small intestine. The most common symptom of a peptic ulcer is stomach pain. There are various risk factors for the development of peptic ulcer disease, but the most important ones are Helicobacter pylori infection and nonsteroidal anti-inflammatory drugs (NSAIDs). Patients generally present with dyspepsia or peptic ulcer bleeding. Acid suppressant therapy, H. pylori eradication, and avoidance of nonst

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Kharitonov, D. V., V. G. Sapozhnikov, and L. A. Kharitonova. "About the constitutional features of gastric and duodenal ulcer in children." Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) 67, no. 6 (2023): 63–67. http://dx.doi.org/10.21508/1027-4065-2022-67-6-63-67.

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Peptic ulcer disease is a fairly rare pathology of childhood. Therefore, it is important to analyze some features of peptic ulcer of the stomach and duodenum in children, depending on the body type.Purpose. To analyze some features of peptic ulcer of the stomach and duodenum in children, depending on the body type.Material and methods. We examined 58 children aged 12–18 years with a diagnosis of peptic ulcer of the stomach and/or duodenum, who underwent endoscopic examination, H. pylori was detected in the biopsy and aero test.Results. Peptic ulcer disease was more often detected in asthenic c

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Kartheek, Chegu* Innaiah Nallaboina Divya Billi Ajay Babu Palaparthi. "A REVIEW ON SOME HOME REMEDIES ACT AS GASRTOPROTECTIVE ACTIVITY." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 02 (2019): 4640–43. https://doi.org/10.5281/zenodo.2581500.

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<em>Ulcer is a common gastrointestinal disorder which is seen among many people. It is basically an inflamed break in the skin or the mucus membrane lining the alimentary tract.</em><em> Peptic ulcers include Gastric ulcers that occur on the inside of the stomach and duodenal ulcers that occur on the inside of the upper portion of your small intestine (duodenum). The most common causes of peptic ulcers are infection with the bacterium Helicobacter pylori (H. pylori) and long-term use of aspirin and certain other painkillers, such as ibuprofen and naproxen sodium. The most common pept

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7

Srivastav, Yash, Vijay Kumar, Yashi Srivastava, and Madhaw Kumar. "Peptic Ulcer Disease (PUD), Diagnosis, and Current Medication-Based Management Options: Schematic Overview." Journal of Advances in Medical and Pharmaceutical Sciences 25, no. 11 (2023): 14–27. http://dx.doi.org/10.9734/jamps/2023/v25i11651.

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A common condition in the world, Peptic Ulcer condition is sometimes referred to as stomach ulcers or peptic ulcers. PUD is caused by a defect in the mucosa of the stomach or duodenum that extends beyond the muscularis mucosa. PUD is the consequence of an imbalance between the aggressive and defensive elements impacting the mucosa, which occurs after gastric mucosal lesions. Peptic ulcer disease (PUD) is a widespread ailment affecting 5–10% of the world's population, with notable racial and regional variations. As a result of an imbalance between the aggressive and defensive elements impacting

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8

Gauri, S. Salunke* Gayatri B. Gaware Rupali N. Tarde Payal A. Pangude Sayyed A. Kirmani. "Anti- Ulcer Activity Of Medicinal Plants." International Journal in Pharmaceutical Sciences 2, no. 1 (2024): 33–36. https://doi.org/10.5281/zenodo.10459255.

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The most prevalent digestive tract condition, peptic ulcers are primarily caused by an imbalance between aggressive and defensive stomach forces. Because of their hectic lifestyles, industrialised, civilised, and developed nations have higher rates of ulcers. Medicinal plants: crucial and productive Plant with so many amazing health benefits that very little of the human body is left. Unaffected by its therapeutic application. It is a significant and potent anti-ulcer. The anti-ulcer properties of herbal Recipe for aloe vera. Recognition and application Herbal remedies with ulcer-preventing pr

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9

Arava Vidyadhari, Thatiparthi Siva prasad, Mangala Teja Divya, et al. "To study the Helicobacter pylori infection in peptic ulcer." World Journal of Advanced Research and Reviews 22, no. 1 (2024): 1801–8. http://dx.doi.org/10.30574/wjarr.2024.22.1.1098.

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Helicobacter pylori is a gram negative bacterium which causes chronic gastritis and plays important roles in peptic ulcer disease, gastric carcinoma, and gastric lymphoma. Its major in the human pathogen that produces inflammation of the stomach and etiologically related to the duodenal ulcer, gastric ulcer, gastric cancer and mucosa-lymphoid tissue. It is weakens the protective mucous coating of the stomach and duodenum, thus allowing acid to get through to the sensitive lining beneath. Both the acid and the bacteria irritate the lining and cause a sore, or ulcer. Helicobacter treated with a

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Arava, Vidyadhari, Siva prasad Thatiparthi, Teja Divya Mangala, et al. "To study the Helicobacter pylori infection in peptic ulcer." World Journal of Advanced Research and Reviews 22, no. 1 (2024): 1801–8. https://doi.org/10.5281/zenodo.14237951.

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Helicobacter pylori is a gram negative bacterium which causes chronic gastritis and plays important roles in peptic ulcer disease, gastric carcinoma, and gastric lymphoma. Its major in the human pathogen that produces inflammation of the stomach and etiologically related to the duodenal ulcer, gastric ulcer, gastric cancer and mucosa-lymphoid tissue. It is weakens the protective mucous coating of the stomach and duodenum, thus allowing acid to get through to the sensitive lining beneath. Both the acid and the bacteria irritate the lining and cause a sore, or ulcer. Helicobacter treated with a

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11

Ali, Md Zulfikar. "Peptic ulcer disease." KYAMC Journal 3, no. 2 (2013): 270–72. http://dx.doi.org/10.3329/kyamcj.v3i2.15164.

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A peptic ulcer, also known as peptic ulcer disease (PUD) is the most common ulcer of an area of the gastrointestinal tract that is usually acidic and thus extremely painful. It is defined as mucosal erosions equal to or greater than 0.5 cm. As many as 70%-90% of such ulcers are associated with Helicobacter pylori, a spiral-shaped bacterium that lives in the acidic environment of the stomach. KYAMC Journal Vol. 3, No.-2, January 2013, Page 270-272 DOI: http://dx.doi.org/10.3329/kyamcj.v3i2.15164

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12

Fomina, L. A. "Calcium-phosphorus balance in comorbid peptic ulcer disease and arterial hypertension and its correction of calcium channel blockers." Medical alphabet 4, no. 38 (2020): 19–22. http://dx.doi.org/10.33667/2078-5631-2019-4-38(413)-19-22.

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Recurrence of peptic ulcer disease, its comorbid with arterial hypertension is accompanied by calcium-phosphorus imbalance, contributing to the increase of acid-peptic factor, the changes of motor function of the stomach, regional microcirculation, activation of the ulcer process. The use of nifedipine in the therapy of comorbid peptic ulcer disease and arterial hypertension, contributes to the restoration of calcium-phosphorus balance, gastric functions and regional microcirculation, reduces the time and increases the frequency of scarring of ulcers.

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13

Kumar, Akhilesh, Dhanesh Kumar, Rajendra Kumar, et al. "Peptic Ulcers and their Complications." Journal of Drug Delivery and Therapeutics 10, no. 3-s (2020): 256–61. http://dx.doi.org/10.22270/jddt.v10i3-s.4082.

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Peptic ulcer disease (PUD) is an uncommon disorder of early life. Peptic ulceration of the stomach or duodenum is usually associated with abnormalities of the gastric mucosa such as gastritis and/or gastropathy. Gastritis and ulcers of the stomach and duodenum can be classified into either primary or secondary depending on their aetiologies. The majority of primary or unexplained peptic ulcers are the result of chronic inflammation caused by Helicobacter pylori infection. However, an increasing number of children with PUD without evidence of H. Pylori infection are now being seen. Rarely PUD i

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14

Ahtshamullah, Chaudhr, Morton Cuthrell Kimberly, and R. Thornton Owen. "Peptic Ulcer Disease; Stomach and Gastric Ulcers, a Concise Review." International Research Journal of Gastroenterology and Hepatology 6, no. 1 (2023): 30–39. https://doi.org/10.5281/zenodo.7737740.

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The most prevalent condition affecting the stomach and duodenum is peptic ulcer disease (PUD), which is linked to Helicobacter pylori (H. pylori) infection. Esophageal, duodenal, and stomach ulcers are all parts of peptic ulcer disease (PUD). Epigastric discomfort is the PUD symptom that commonly occurs. Proton Pump Inhibitors (PPI), Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), and antibiotics are widely used to treat PUD, which is caused by an imbalance between offensive and defensive forces. Abdominal discomfort, nausea, vomiting, weight loss, and bleeding or perforation with the complicat

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Ahtshamullah, Chaudhry, Morton Cuthrell Kimberly, and R. Thornton Owen. "Peptic Ulcer Disease; Stomach and Gastric Ulcers, a Concise Review." International Research Journal of Gastroenterology and Hepatology 6, no. 1 (2023): 30–39. https://doi.org/10.59283/IRJGH.

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The most prevalent condition affecting the stomach and duodenum is peptic ulcer disease (PUD), which is linked to Helicobacter pylori (H. pylori) infection. Esophageal, duodenal, and stomach ulcers are all parts of peptic ulcer disease (PUD). Epigastric discomfort is the PUD symptom that commonly occurs. Proton Pump Inhibitors (PPI), Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), and antibiotics are widely used to treat PUD, which is caused by an imbalance between offensive and defensive forces. Abdominal discomfort, nausea, vomiting, weight loss, and bleeding or perforation with the complicat

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16

RaviKKumar, V. R., Sanjesh Rathi, Shubham Singh, et al. "A Comprehensive Review on Ulcer and Their Treatment." Chinese Journal of Applied Physiology 39 (2023): e20230006. http://dx.doi.org/10.62958/j.cjap.2023.006.

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A peptic ulcer is a lesion (sore) on the stomach lining, or duodenum. Peptic ulcers are probably a twentieth-century condition. The ulcer disease continues to be a significant source of worldwide morbidity and mortality. The Gastrointestinal ulcers and duodenal ulcers are considered the two most extreme types of peptic ulcers. Peptic ulcers are found to be caused by an excess of violent factors including Hydrochloric acid (HCL) pepsin, refluxed bile leukotrienes (LT), reactive oxygen species (ROS) and protective factors, these include mucus-bicarbonate barrier functions, prostaglandins (PGs),

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17

Anand, Shubham, Namrata Mishra, Namrata Mishra, Manoj Kumar Bajhaiya, and Nisha Verma. "A comprehensive review of the mechanism of action in peptic ulcer pathogenesis." Future Journal of Pharmaceuticals and Health Sciences 4, no. 4 (2024): 1–9. http://dx.doi.org/10.26452/fjphs.v4i4.656.

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Up to 10% of people worldwide suffer from peptic ulcer disease, making it a common yet serious chronic condition. Peptic ulcers develop when stomach juice pH is high and mucosal defenses are weakened. The infection with Helicobacter pylori (H.) and nonsteroidal anti-inflammatory medicines (NSAIDs) have been linked to decreased mucosal resilience to damage. Internal gastrointestinal (GI) disruption due to the production of gastric acid or pepsin is what defines peptic ulcer disease (PUD). The stomach and the first part of the duodenum are common sites for the phenomenon. The jejunum, distal duo

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18

Mohammed, Ezz Basnawi Bayan Almaimany HussamAddin Ali AlTarouti Ali Hasan Abdulla Haneen Mohamed Sibieh Hamood Ali Alharbi Meshal Ali Alasmari Marwan Mohammed Alhumaidi Hanan Menihi Al Joodi Salha Mofareh Ghazwani Lamees yahya Ayedh. "PEPTIC ULCER DISEASE-DIAGNOSIS AND TREATMENT." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 05, no. 12 (2018): 14073–79. https://doi.org/10.5281/zenodo.1845617.

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<strong><em>Introduction:</em></strong><em> The acid peptic injury in the gastrointestinal tract is called peptic ulcer, it results from a rupture in the mucosa to the submucosa. Generally, most of the peptic ulcers locate in the stomach or in the duodenum in its proximal part, however, the may also locate in Meckel’s diverticulum or in the oesophagus. In this review, we mean by the “peptic ulcer” term the ones in the stomach or duodenum.</em> <strong><em>Aim of work: </em></strong><em>In this review, we will discuss the recent strategies to diagnose and treat peptic ulcer di

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Kharitonov, D. V., V. G. Sapozhnikov, and L. A. Kharitonova. "About the constitutional features of gastric and duodenal ulcer in children." Experimental and Clinical Gastroenterology, no. 6 (November 21, 2022): 36–40. http://dx.doi.org/10.31146/1682-8658-ecg-202-6-36-40.

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The goal of research. To analyze some features of peptic ulcer of the stomach and duodenum in children, depending on the type of constitution. Material and methods of research. We examined 58 children aged 12-18 years with a diagnosis of peptic ulcer of the stomach and/or duodenum, who underwent endoscopic examination, Hp was detected in the biopsy and aero test. Results. Peptic ulcer disease was more often detected in asthenic children (67.2%), less often in hypersthenic (17.3%) and normosthenics (15.5%). Various research methods in asthenic children (97.4%) revealed the presence of Hp more o

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Vavilov, A. M. "Peculiarities of ageing at patients with stomach ulcer." Bulletin of Siberian Medicine 3, no. 4 (2004): 44–57. http://dx.doi.org/10.20538/1682-0363-2004-4-44-57.

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The aim of investigation is to compare the rate of ageing at patients with stomach ulcer (SU) and of practically healthy people. Dynamics of biological age of 406 patients with SU aged 40—59 years and of comparable practically healthy groups has been observed. The ageing of patients with peptic mediagastric pyloroduodenal ulcers develops faster than of practically healthy people. The rate of ageing at patients with peptic mediagastric pyloroduodenal ulcers depends on the clinical course and effected therapy.

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Awuchi, Chinaza Godswill, Purabi Saha, Vandana Sonaji Amle, et al. "A Study of Various Medicinal Plants used in Ulcer Treatment: A Review." Journal for Research in Applied Sciences and Biotechnology 2, no. 1 (2023): 234–46. http://dx.doi.org/10.55544/jrasb.2.1.34.

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Many people suffer from ulcer, a disorder of the digestive tract. Simply put, it's an inflamed break in the skin or the mucus membrane lining the digestive tract. Whenever there is a change in the equilibrium, such as increased aggression or decreased mucosal resistance, ulceration develops. Reasons for this could include drug use, poor diet, stress, and other similar factors. Peptic ulcers are a general term for any type of stomach or duodenal ulcer. To develop, peptic ulcers need mucosal defences to be compromised in addition to gastric juice acid and peptic activity. Ulcers can be treated w

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Nwozor, C.M. "The Role of Helicobacter pylori in Peptic Ulcer Disease." Greener Journal of Medical Sciences 3, no. 6 (2013): 222–27. https://doi.org/10.5281/zenodo.3402254.

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The link between <em>Helicobacter pylori (H. Pylori)</em> infection and peptic ulceration is now well established: presence of infection is a strong risk factor for later ulcer development and ulcers rarely occur in the absence of <em>H. pylori</em> or the other main risk factor, non steroidal anti-inflammatory drugs (NSAIDs). The role of <em>H pylori</em> in peptic ulceration in human is presented in this paper. A peptic ulcer is an excoriated area of stomach or intestinal mucosa caused principally by the digestive action of gastric juice. The two most common fac

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Martinez, Glendy Alejandra. "Risk Factors for Developing Peptic Ulcer Disease." International Journal Of Medical Science And Clinical Research Studies 03, no. 02 (2023): 174–76. https://doi.org/10.5281/zenodo.7611536.

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Peptic ulcer disease (PUD) is predicted to affect between 0.1 and 0.3 percent of the population each year. PUD develops at a rate of roughly 1% per year in Helicobacter pylori (H. pylori) infected persons, which is 6 to 10 times higher than in uninfected people. The prevalence of PUD increases with age in both duodenal and stomach ulcers. Two factors contribute to peptic ulcer disease: H. pylori infection and the use of nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs have also been related to an increased risk of complications from peptic ulcer disease, such as gastrointestinal bleeding,

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SMITH, JAMES L. "The Role of Gastric Acid in Preventing Foodborne Disease and How Bacteria Overcome Acid Conditions†." Journal of Food Protection 66, no. 7 (2003): 1292–303. http://dx.doi.org/10.4315/0362-028x-66.7.1292.

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The secretion of hydrochloric acid by the stomach plays an important role in protecting the body against pathogens ingested with food or water. A gastric fluid pH of 1 to 2 is deleterious to many microbial pathogens; however, the neutralization of gastric acid by antacids or the inhibition of acid secretion by various drugs may increase the risk of food- or waterborne illnesses. Peptic ulcer disease is often treated by decreasing or eliminating gastric acid secretion, and such treatment blocks the protective antibacterial action of gastric fluid. The majority of peptic ulcer disease cases orig

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Le, Quoc Anh, and Ngoc Le Nguyen. "Study on the relationship between traditional medicine syndromes in patients with peptic ulcer disease and peptic ulcer disease complicated by gastrointestinal hemorrhage." Tạp chí Y Dược Huế 15, no. 2 (2025): 44–50. https://doi.org/10.34071/jmp.2025.2.6.

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Background: Peptic ulcer disease is quite common in the community, prone to recurrence, and associated with many dangerous complications, including gastrointestinal bleeding. According to traditional medicine, described in peptic ulcer disease belong to the category of “gastric upset”. To assist physicians in diagnosing and effectively treating this disease, while also reducing the risk of gastrointestinal bleeding, we conducted this study. Objectives: To investigate certain characteristics of traditional medicine syndromes and patterns in patients with peptic ulcer disease and those with pept

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Vimala, G., and F. Gricilda Shoba. "A Review on Antiulcer Activity of Few Indian Medicinal Plants." International Journal of Microbiology 2014 (2014): 1–14. http://dx.doi.org/10.1155/2014/519590.

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Ulcer is a common gastrointestinal disorder which is seen among many people. It is basically an inflamed break in the skin or the mucus membrane lining the alimentary tract. Ulceration occurs when there is a disturbance of the normal equilibrium caused by either enhanced aggression or diminished mucosal resistance. It may be due to the regular usage of drugs, irregular food habits, stress, and so forth. Peptic ulcers are a broad term that includes ulcers of digestive tract in the stomach or the duodenum. The formation of peptic ulcers depends on the presence of acid and peptic activity in gast

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SAKHABETDINOVA, KAMILIA N., BULAT A. SAKHABETDINOV, and NAIL B. AMIROV. "COMORBIDITY AS A FACTOR OF GASTRODUODENAL ULCER DEVELOPMENT IN ELDERLY AND SENILE PATIENTS." Bulletin of Contemporary Clinical Medicine 17, no. 6 (2024): 84–96. https://doi.org/10.20969/vskm.2024.17(6).84-96.

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Introduction. Peptic ulcer disease is a chronic recurrent multifactorial disease that takes its course with alternating exacerbations and remissions and is manifested by ulcerative defects in the mucous membrane of the stomach and duodenum, which is based on an imbalance of aggressive and protective factors with a predominance of ВЕСТНИК СОВРЕМЕННОЙ КЛИНИЧЕСКОЙ МЕДИЦИНЫ 2024 Том 17, вып. 6 85ОБЗОРЫ the former ones. Of particular interest is the comparative characteristics of gastric and duodenal ulcers in the patients of senile and elderly age groups due to their pathogenetic features and sing

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Sivakumar, Aran, and Benjamin Stubbs. "Peptic ulcer disease." InnovAiT: Education and inspiration for general practice 14, no. 6 (2021): 372–78. http://dx.doi.org/10.1177/17557380211005791.

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Peptic ulcer disease (PUD) is defined as a disruption in the innermost lining of the gastrointestinal tract, due to the secretion of gastric acid or pepsin. The disruption is in the gastric epithelial layer, specifically the muscularis mucosae. PUD normally affects the stomach along with the first and second parts of the duodenum, although it is not limited to these areas. Typically, gastric ulcers induce upper abdominal pain within 30 minutes of eating, whereas duodenal ulcers cause discomfort much later. Endoscopic and histological investigations are the key to early identification and treat

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Rahatullah, Haidari Said. "PREVALENCE AND ASSOCIATED FACTORS OF PEPTIC ULCER DISEASE AMONG DYSPEPTIC PATIENTS AT ENDOSCOPY UNIT IN KABUL, AFGHANISTAN." Journal of Applied Pharmaceutical Sciences and Research 6, no. 2 (2023): 19–24. http://dx.doi.org/10.31069/japsr.v6i2.04.

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Introduction: Dyspepsia is a medical term utilized to describe a cluster of symptoms related to the digestive system, particularly in the upper gastrointestinal tract. The most prevalent causes of dyspepsia encompass gastro esophageal reflux disease (GERD), peptic ulcer disease (PUD), and non-ulcer dyspepsia (NUD). A peptic ulcer is a sore or erosion that forms in the lining of the stomach, upper part of the small intestine, or lower part esophagus. Materials and Methods: The study incorporated 500 dyspeptic patients who underwent upper gastrointestinal endoscopic assessments. This hospi

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Pattewar, S.G. Sakhare R. S. Nagoba Shivappa N. Sugave B. K. Moholkar Aparark V. "A REVIEW: TRADITIONAL ANTIULCER COMPOUNDS." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES 06, no. 01 (2019): 911–17. https://doi.org/10.5281/zenodo.2538342.

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<em>Peptic ulcer is a break in the lining of the stomach, first part of the small intestine, or duodenum. The duodenumis the first part of the small intestine. Incompatible to popular belief, ulcers are not caused by spicy food or stress but other factors causes’ peptic ulcer main cause of peptic ulcer called H. pylori bacterial infection and long term use of NSAIDS medication. The main goals for treating a peptic ulcer include eliminating the underlying cause (particularly H. pylori infection or use of NSAIDs), NSAIDs inhibit the cyclooxygenase enzyme, Cyclooxygenase stop the secretion

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Deshpande, Mangirish, Pearl Dighe, and Sujit Nagare. "A Review of Antiulcer Activity of Some Medicinal Plants." Journal of Drug Delivery and Therapeutics 14, no. 8 (2024): 201–13. http://dx.doi.org/10.22270/jddt.v14i8.6722.

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Peptic ulcer is a gastrointestinal disorder and with increased prevalence. Peptic ulcer is breaking of endothelial lining of stomach and exposing underlying tissues. Peptic ulcer occurs due to high secretion of acid and reduced defensive factors in stomach and duodenum. It is imbalance between aggressive and defensive factors. Non-steroidal anti-inflammatory drugs and Helicobacter pylori infection also increases the risk of peptic ulcer. Indiscriminate use of synthetic drugs leads to adverse effects and concomitant use of antibiotics potentiates drug-drug interaction thus search of drugs from

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Levkov, A. I. "To the question of the moments contributing to the occurrence of postoperative peptic ulcer of the jejunum." Kazan medical journal 29, no. 3 (2021): 223–27. http://dx.doi.org/10.17816/kazmj80592.

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Despite the large number of works on the issue of peptic ulcer of the small intestine, the latter has not lost its relevance and interest to date.Peptic ulcer is one of the most serious complications of gastric surgery. Our material is compiled by the surgical department. Penza hospital 1382 operations performed for stomach and duodenal ulcers. Of these, 1254 operations were performed during the year. and 128 for gastric resection. For this number of operations, until recently, we have 20 cases of postoperative peptic ulcers.

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Fajar Amirulah, Magfirah Magfirah, Maria Caecilia Novi Yanti, et al. "Pengenalan Obat dan Gaya Hidup untuk Penderita Ulkus Peptikum dan GERD." Karunia: Jurnal Hasil Pengabdian Masyarakat Indonesia 3, no. 4 (2024): 168–78. https://doi.org/10.58192/karunia.v3i4.2700.

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Peptic ulcer is a condition where there is a wound or ulcer on the inner lining of the stomach. Gastroesophageal Reflux Disease (GERD) occurs when stomach contents flow back into the esophagus and can damage the mucosal lining of the esophagus. Extension activities carried out at SMA Santo Lukas 1, obtained pre-test results for correct answers of 82.08% and for wrong answers of 17.92%, while the post-test results showed a significant increase after the provision of material, namely for correct answers of 93.33% and wrong answers of 6.67%. This shows that most students understand the informatio

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Varshini, R., P. Suganyadevi, and L. Hariprasath. "Phytochemical and antiulcer properties of aqueous crude extract of Sargassum wightii from subtidal region of the Mandapam coast area, Gulf of Mannar, India." Research Journal of Biotechnology 18, no. 4 (2023): 64–73. http://dx.doi.org/10.25303/1804rjbt064073.

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Peptic ulcers (PU) are sores or lesions in the gastrointestinal mucosa extending throughout the muscularis mucosae, typically characterized by different stages of necrosis, neutrophil infiltration, blood flow reduction, increased oxidative stress and inflammation. Peptic ulcer is the disease that is associated with wound in the muscular mucous layer of the stomach. Sargassum wightii is a brown seaweed that contains bioactive components including fucoidan and fucoxanthin as well as large amounts of polyphenols and is used by locals for the treatment of peptic ulcer. The objective of this study

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Singh, Karanvir, Rajesh Kumar, Ajeet Pal Singh, Meenakshi Malhotra, Amar Pal Singh, and Ritu Rani. "Peptic Ulcer: A review." International Journal of Medical, Pharmacy and Drug Research 8, no. 2 (2024): 38–46. http://dx.doi.org/10.22161/ijmpd.8.2.5.

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Peptic ulcers, characterized by painful sores that develop on the lining of the stomach, small intestine, or esophagus, are a prevalent gastrointestinal condition affecting millions worldwide. This abstract provides an overview of the causes, symptoms, and treatment options for peptic ulcers. Peptic ulcers primarily stem from the imbalance between aggressive factors such as gastric acid secretion, pepsin, and Helicobacter pylori infection, and defensive mechanisms like mucosal barrier integrity and blood flow. Lifestyle factors such as excessive alcohol consumption, smoking, and stress, along

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Al Abri, MD, Maather, Ghaitha Al Mahruqi, MD, and Hani Al Qadhi, FRCSC. "Recurrent Peptic Ulcer Perforation: A Case Report." International Journal of Innovative Research in Medical Science 7, no. 01 (2022): 62–65. http://dx.doi.org/10.23958/ijirms/vol07-i01/1329.

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Background: Refractory peptic ulcers are ulcers in the stomach or duodenum that do not heal after eight to twelve weeks of medical/surgical treatment or those that are associated with complications despite medical tssreatment. We herein present a case of a 44 year old man with a recurrent perforated duodenal ulcer requiring emergent surgical intervention.

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Haamadi, Amer A., Mohsen Hashim Risan, and Hassan M. Abo Almaali. "Helicobacter Pylori, Infection, Virulence Factors and Treatment A Review." Biomedicine and Chemical Sciences 1, no. 4 (2022): 278–88. http://dx.doi.org/10.48112/bcs.v1i4.289.

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Gastric and ulcer peptic disease is a common disease in the community. Considering the close relationship between peptic ulcer and gastritis caused by Helicobacter pylori. The prevalence of H. pylori increased markedly with age with the maximum colonization (81.5%) occurring in adults (40-60 years). H. pylori are bacteria that can cause an infection in the stomach or duodenum (first part of the small intestine). It’s the most common cause of peptic ulcer disease. H. pylori can also inflame and irritate the stomach lining (gastritis). Untreated, long-term H. pylori infection can lead to stomach

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Mantry, Shubhrajit, Sahil Shaikh, Shubham Shinde, Shital Bidkar, and Ganesh Dama. "Preliminary Study on the Composition of Nanoparticles for the Treatment of Peptic Ulcer." International Journal of Current Research and Review 14, no. 08 (2022): 16–25. http://dx.doi.org/10.31782/ijcrr.2022.14803.

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One of the most frequent gastrointestinal issues is a gastric ulcer. Throughout their lives, peptic ulcer disease affects more than 10% of the adult population in Western countries. The pathogenesis of peptic ulcer disease is based on an imbalance between mucosal defense factors (bicarbonate, mucin, prostaglandin, nitric oxide, and other peptides and growth factors) and hazardous chemicals (acid and pepsin). Certain acid-related illnesses can be addressed and prevented by lowering gastric acidity or improving mucosal protection. In the treatment of stomach ulcers, nanoparticles are being devel

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Zahid, Rabia, Muhammad Akram, Muhammad Riaz, Naveed Munir, and Muhammad Shehzad. "Phytotherapeutic modalities for the management of Helicobacter pylori associated peptic ulcer." European Journal of Inflammation 18 (January 2020): 205873922096830. http://dx.doi.org/10.1177/2058739220968308.

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Due to an imbalance between aggressive factors known as hydrochloric acid (HCl), pepsin, leukotrienes, refluxed bile, defensive factors and reactive oxygen species, the peptic ulcer is formed in the stomach and duodenum which mostly include the function of prostaglandins, mucus bicarbonate barrier, enzymatic antioxidants, and some growth factors. H. pylori infection remained one of the considerable causes of peptic ulcer as it caused hypochlorhydria and struck off the defense mechanism of the stomach. The nonsteroidal anti-inflammatory drugs (NSAIDs) and stress are the most prevailing causes o

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KHASANOV, ANVAR GINIYATOVICH, ILDAR FANUSOVICH SUFIYAROV, RADIK RADIFOVICH FAYAZOV, AZAMAT FUATOVICH BADRETDINOV, and YULIA RIYAZOVNA SAGADATOVA. "ETIOPATHOGENETIC BASES OF THE DEVELOPMENT OF PEPTIC ULCER DISEASE (LITERATURE REVIEW)." Archivarius 7, no. 6(60) (2021): 16–18. http://dx.doi.org/10.52013/2524-0935-60-6-3.

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This article provides basic information about the etiology and pathophysiological mechanisms of the development of peptic ulcer of the stomach and duodenum. A brief review of the literature is conducted, the main causes of peptic ulcer disease are considered: acid-peptic factor, infection with Helicobacter pylori, etc.

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Selma İrem SÖZEN, Hafize Kovancı, Muhammed Said Dalkılıç, and Selim SÖZEN. "Nutrition and Helicobacter pylori infection in gastric disease." World Journal of Advanced Research and Reviews 18, no. 3 (2023): 021–30. http://dx.doi.org/10.30574/wjarr.2023.18.3.1005.

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H. pylori is a highly prevalent bacterial infection among humans. It is considered the major etiological factor in the development of chronic gastritis, peptic ulcers, and stomach cancer. Nutritional therapy is important for the prevention of gastritis, as well as for reducing stomach irritation (irritation) in the treatment of gastritis, and it plays an important role by helping to eradicate or strengthen the stomach wall. Chronic gastritis should be diagnosed before it progresses and causes fatal diseases such as peptic ulcer or cancer, and it should be treated with both a healthy diet and a

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Albayrak, Abdulmecit, Huseyin Bekmez, Melis Kiliç, et al. "INVESTIGATING THE THERAPEUTIC POTENTIAL OF BENIDIPINE IN INDO-METHACIN-INDUCED PEPTIC ULCERS: AN EXPERIMENTAL STUDY IN RATS." Azerbaijan Pharmaceutical and Pharmacoterapy Journal 23, no. 2 (2023): 44–53. http://dx.doi.org/10.58495/szfi8096.

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Objective: Peptic ulcer disease is a prevalent gastrointestinal disorder associated with escalating global mortality rates and a heightened risk of gastric cancer. This study investigates the therapeutic potential of Benidipine, an L-type calcium channel blocker known for its antioxidant properties, in an indomethacin-induced peptic ulcer model in rats. Methods: Thirty-six male albino Wistar rats were divided into six groups and subjected to various drug treatments, including Indomethacin, Famotidine, and Benidipine. Stomach tissue samples were collected for analysis. Results: Macroscopic exam

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Sultana, M. Tarannum, Shakir Basha, Y. Sai Charan Teja, and Karthick S. "Alleviating Ulcer Burdens Examining the Potential of Albizia Odoratissima Bark Extract as a Therapeutic Agent in Mice." UTTAR PRADESH JOURNAL OF ZOOLOGY 45, no. 11 (2024): 271–84. http://dx.doi.org/10.56557/upjoz/2024/v45i114095.

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Ulcerative stomach disease continues to be a prevalent gastrointestinal illness associated with high worldwide morbidity and medical costs. While nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection are well-known risk factors for the development of peptic ulcers, recent evidence suggests a complex interaction between host factors and the gut microbiota in ulcer etiology. This study provides a comprehensive review of recent research investigating the relationship between the genesis and progression of peptic ulcers and dysbiosis of the gut microbiota. The study highl

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Podoluzhnyi, V. I., A. B. Startsev, Yu A. Kokoulina, and I. A. Radionov. "Peptic ulcer of gastrojejunal anastomosis: an undeservedly neglected problem." Fundamental and Clinical Medicine 8, no. 2 (2023): 87–92. http://dx.doi.org/10.23946/2500-0764-2023-8-2-87-92.

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Aim. To evaluate the incidence and causes of peptic ulcers of the gastrojejunal anastomosis to develop the corresponding preventive measures.Materials and Methods. We retrospectively analysed the case histories of the patients with peptic ulcer who have been admitted to our surgical unit during 1981-1996 and 2007-2021. A total of 62 patients with peptic ulcers of the anastomosis who underwent Billroth II resection were examined radiographically, endoscopically, and intraoperatively, including proteolysis and acidity measurements.Results. While the number of gastric operations has been reduced

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Kim, Grace E., and Dennis Chen. "Transcatheter Arterial Radioembolization–Induced Gastric Ulcer in an Excluded Stomach After Roux-en-Y Gastric Bypass." ACG Case Reports Journal 11, no. 7 (2024): e01399. http://dx.doi.org/10.14309/crj.0000000000001399.

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ABSTRACT Transcatheter arterial radioembolization (TARE) is a common locoregional treatment for hepatocellular carcinoma. It is associated with peptic ulcer disease in up to 5% of patients. A 70-year-old man with Roux-en-Y gastric bypass and liver cirrhosis with hepatocellular carcinoma treated with TARE 6 months earlier was evaluated for continued melena and was found to have an ulcer in the excluded stomach. This was successfully treated with liquid proton pump inhibitor through gastrostomy tube to the excluded stomach. This represents a unique case of successful management of TARE-induced p

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Selma, İrem SÖZEN, Kovancı Hafize, Said Dalkılıç Muhammed, and SÖZEN Selim. "Nutrition and Helicobacter pylori infection in gastric disease." World Journal of Advanced Research and Reviews 18, no. 3 (2023): 021–30. https://doi.org/10.5281/zenodo.8429966.

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<em>H. pylori</em> is a highly prevalent bacterial infection among humans. It is considered the major etiological factor in the development of chronic gastritis, peptic ulcers, and stomach cancer. Nutritional therapy is important for the prevention of gastritis, as well as for reducing stomach irritation (irritation) in the treatment of gastritis, <em>and it </em>plays an important role by helping to eradicate or strengthen the stomach wall.  Chronic gastritis should be diagnosed before it progresses and causes fatal diseases such as peptic ulcer or cancer, and it should be

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47

Sujal, Sujal, Aanchal Chandel, Dr Neeraj Bhandari, and Amisha Gautam. "A Review Article on Peptic Ulcer." International Journal of Pharmaceutical Research and Applications 09, no. 06 (2024): 995–1006. https://doi.org/10.35629/4494-09069951006.

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Peptic ulcer disease (PUD) refers to the development of open sores or lesions on the lining of the stomach, duodenum, or esophagus, caused by an imbalance between aggressive factors (like gastric acid) and protective factors. The two most common types of peptic ulcers are gastric ulcers, which form in the stomach, and duodenal ulcers, which occur in the first part of the small intestine. The primary etiological factors for PUD include infection with Helicobacter pylori, long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs), and excessive alcohol consumption, though stress and smoking

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Salini, VS, RR Geethesh, Ravindra Angadi, Ashok Kumar BN, and VS Sushmitha. "Experimental evaluation of preventive action of baladimandura in gastric ulcer based on histopathological reports." Journal of Scientific and Innovative Research 10, no. 3 (2021): 76–80. http://dx.doi.org/10.31254/jsir.2021.10304.

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Background: Peptic ulcer diseases constitute a major disease that affects the Gastro Intestinal tract. Gastric ulcers are one among the types of Peptic ulcers in which the ulcers are manifested in the lining of gastric mucosa. Annadrava shoola can be correlated with gastric ulcer due to its similarity in symptomatology. Baladimandura is a drug of choice in the management of Amlapitta and Parinamashoola mentioned in Rasakamadhenu. Aims & Objectives: To evaluate the gastric ulcer preventive action of Baladimandura in pyloric ligated albino rats through the histopathology examination of stoma

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Thachuk, Anna Valerienvna. "Stomach Peptic Ulcer: Confined Gastric Perforation." Journal of Diagnostic Medical Sonography 24, no. 1 (2008): 39–42. http://dx.doi.org/10.1177/8756479307313279.

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Dr., G. Usha kiran, P.Supriya, Naga Anjani V., Jeevan kumar P., Jasmin Sk., and Sai siva teja M. "Comparitive Evaluation of Different Anti-Ulcer Drugs using Standard Procedures." International Journal of Innovative Science and Research Technology 7, no. 12 (2023): 1736–45. https://doi.org/10.5281/zenodo.7537954.

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Ulcer is a common gastro intestinal disorder. It is fundamentally a kindled break in skin on the mucous film coating the wholesome lot. Ulceration happens when there is an unsettling influence in the typical balance brought about by either improved hostility (or) lessened mucosal obstruction. Ulcers are most common on the skin of the lower extremities and in the gastro intestinal tract, although they may be encountered at almost any site. Peptic ulcers are erosion lining of the stomach. Generally, pain occurs when the stomach is empty and relives after eating. A duodenal ulcer is most common i

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