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Relevant bibliographies by topics / Peptide Secretion

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Academic literature on the topic 'Peptide Secretion'

Author: Grafiati

Published: 7 June 2025

Last updated: 2 August 2025

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Journal articles on the topic "Peptide Secretion"

1

Sutliff, V. E., J. P. Raufman, R. T. Jensen, and J. D. Gardner. "Actions of vasoactive intestinal peptide and secretin on chief cells prepared from guinea pig stomach." American Journal of Physiology-Gastrointestinal and Liver Physiology 251, no. 1 (1986): G96—G102. http://dx.doi.org/10.1152/ajpgi.1986.251.1.g96.

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Vasoactive intestinal peptide and secretin increased cellular cAMP and pepsinogen secretion in dispersed chief cells from guinea pig gastric mucosa. With each peptide there was a close correlation between the dose-response curve for changes in cellular cAMP and that for changes in pepsinogen secretion. Vasoactive intestinal peptide-(10–28) and secretin-(5–27) had no agonist activity and antagonized the actions of vasoactive intestinal peptide and secretin on cellular cAMP and pepsinogen secretion. Studies of binding of 125I-vasoactive intestinal peptide and of 125I-secretin indicated that gast

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Park, Hyung Seo, Hyeok Yil Kwon, Yun Lyul Lee, William Y. Chey, and Hyoung Jin Park. "Role of GRPergic neurons in secretin-evoked exocrine secretion in isolated rat pancreas." American Journal of Physiology-Gastrointestinal and Liver Physiology 278, no. 4 (2000): G557—G562. http://dx.doi.org/10.1152/ajpgi.2000.278.4.g557.

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Effects of intrapancreatic gastrin-releasing peptide (GRP)-containing neurons on secretin-induced pancreatic secretion were investigated in the totally isolated perfused rat pancreas. Electrical field stimulation (EFS) increased secretin (12 pM)-induced pancreatic secretions of fluid and amylase. EFS induced a twofold increase in GRP concentration in portal effluent, which was completely inhibited by tetrodotoxin but not modified by atropine. An anti-GRP antiserum inhibited the EFS-enhanced secretin-induced secretions of fluid and amylase by 12 and 43%, respectively, whereas a simultaneous inf

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Herrmann-Rinke, C., A. Vöge, M. Hess, and B. Göke. "Regulation of glucagon-like peptide-1 secretion from rat ileum by neurotransmitters and peptides." Journal of Endocrinology 147, no. 1 (1995): 25–31. http://dx.doi.org/10.1677/joe.0.1470025.

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Abstract Food ingestion induces a rapid increase in the insulinotropic glucagon-like peptide-1 (GLP-1) in plasma. Paradoxically, GLP-1 originates from the lower intestines and therefore a complex regulation of postprandial GLP-1 secretion must exist. This was addressed in the present study by utilizing an isolated vascularly perfused rat ileum preparation. Peptides and neurotransmitters thought to be candidate mediators triggering GLP-1 secretion were arterially infused and GLP-1 was measured in the venous effluent. Arterial infusion of cholinergic agonists strongly enhanced GLP-1 secretion wh

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Ahrén, Bo. "Regulatory peptides in the thyroid gland — a review on their localization and function." Acta Endocrinologica 124, no. 3 (1991): 225–32. http://dx.doi.org/10.1530/acta.0.1240225.

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Abstract. It has been demonstrated that nerve fibres storing immunoreactivity of vasoactive intestinal polypeptide, peptide histidine iso-leucine, neuropeptide Y, substance P, calcitonin gene-related peptide, galanin, and cholecystokinin exists in the thyroid, though the content of these neuropeptides is lower in the thyroid than in other organs, like in the gut. Furthermore, the parafollicular C-cells have been shown to harbour several different peptides: calcitonin, somatostatin, calcitonin gene-related peptide, gastrin-releasing peptide, katacalcin and helodermin. In addition, other regulat

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Fiorucci, Stefano, Eleonora Distrutti, Barbara Federici, et al. "PAR-2 modulates pepsinogen secretion from gastric-isolated chief cells." American Journal of Physiology-Gastrointestinal and Liver Physiology 285, no. 3 (2003): G611—G620. http://dx.doi.org/10.1152/ajpgi.00388.2002.

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In the present study, we investigated whether activation of protease-activated receptor type 2 (PAR-2) with SLIGRL (SL)NH2, a short mimetic agonistic peptide, directly stimulates pepsinogen secretion from gastric-isolated, pepsinogen-secreting (chief) cells. Immunostaining of gastric-dispersed chief cells with a specific anti-PAR-2 antibody demonstrated expression of PAR-2 receptors on membrane and cytoplasm. SL-NH2 and trypsin potently stimulated pepsinogen secretion (EC50 = 0.3 nM) and caused Ca2+ mobilization (EC50 = 0.6 nM). In contrast to SL-NH2, the scramble peptide LSIGRL-NH2 failed to

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Proaño-Bolaños, Carolina, Ailín Blasco-Zúñiga, José Rafael Almeida, et al. "Unravelling the Skin Secretion Peptides of the Gliding Leaf Frog, Agalychnis spurrelli (Hylidae)." Biomolecules 9, no. 11 (2019): 667. http://dx.doi.org/10.3390/biom9110667.

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Frog skin secretions contain medically-valuable molecules, which are useful for the discovery of new biopharmaceuticals. The peptide profile of the skin secretion of Agalychnis spurrelli has not been investigated; therefore, the structural and biological characterization of its compounds signify an inestimable opportunity to acquire new biologically-active chemical scaffolds. In this work, skin secretion from this amphibian was analysed by molecular cloning and tandem mass spectrometry. Although the extent of this work was not exhaustive, eleven skin secretion peptides belonging to five peptid

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Herranz, Carmen, and Arnold J. M. Driessen. "Sec-Mediated Secretion of Bacteriocin Enterocin P by Lactococcus lactis." Applied and Environmental Microbiology 71, no. 4 (2005): 1959–63. http://dx.doi.org/10.1128/aem.71.4.1959-1963.2005.

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ABSTRACT Most lactic acid bacterium bacteriocins utilize specific leader peptides and dedicated machineries for secretion. In contrast, the enterococcal bacteriocin enterocin P (EntP) contains a typical signal peptide that directs its secretion when heterologously expressed in Lactococcus lactis. Signal peptide mutations and the SecA inhibitor azide blocked secretion. These observations demonstrate that EntP is secreted by the Sec translocase.

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Giovannini, M. G., L. Poulter, B. W. Gibson, and D. H. Williams. "Biosynthesis and degradation of peptides derived from Xenopus laevis prohormones." Biochemical Journal 243, no. 1 (1987): 113–20. http://dx.doi.org/10.1042/bj2430113.

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Peptides present in the skin secretion of the South African frog, Xenopus laevis, have been analysed by fast atom bombardment mass spectrometry and h.p.l.c. in the mass range 500-3200 Da. We have investigated the effects of successive glandular secretions induced by noradrenaline injections on these peptide levels and have found that the replenishment of the whole range of peptides is complete within 2-6 days. Intact secretory vesicles free of cellular contaminants contain a relatively large number of peptides with molecular masses in the range 2400-2700 Da. We have termed these peptides prima

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Ishibashi, Miyuki, Tohru Yamaji, Fumimaro Takaku, et al. "Effect of GnRH-associated peptide on prolactin secretion from human lactotrope adenoma cells in culture." Acta Endocrinologica 116, no. 1 (1987): 81–84. http://dx.doi.org/10.1530/acta.0.1160081.

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Abstract. The effect of GnRH-associated peptide on PRL secretion by human pituitary lactotropes in culture was studied. Pituitary adenomas obtained at selective transsphenoidal adenomectomy from a patient with prolactinoma, and two patients with mixed GH- and PRL-secreting pituitary adenomas were cultured in monolayer. When cells were incubated with dopamine (10 nmol/l), a significant inhibition in PRL secretion was observed in all the experiments, which was blocked by co-incubation with haloperidol. In mixed GH- and PRL-secreting adenoma cells, dopamine likewise decreased GH secretion. Incuba

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Karim, Kazi Muhammad Rezaul, та Tasmia Tasnim. "EVALUATION OF RECOMBINANT GLUCOAMYLASE EXPRESSION BY A NATIVE AND α-MATING FACTOR SECRETION SIGNAL IN PICHIA PASTORIS". Journal of microbiology, biotechnology and food sciences 11, № 5 (2022): e3428. http://dx.doi.org/10.55251/jmbfs.3428.

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Raw starch degrading enzyme specially glucoamylase with starch binding domain (SBD) has great values in the starch processing industry because it digests the starch particles below the gelatinization temperature by releasing glucose from the non-reducing ends sequentially. The purpose of the study was to measure the secretion levels of recombinant glucoamylase from Pichia pastoris, by using the α-mating factor secretion signal peptide (α-MF) and the native signal peptide of glucoamylase from Aspergillus flavus NSH9. The Aspergillus flavus NSH9 gene (with and without native signal sequences), e

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Dissertations / Theses on the topic "Peptide Secretion"

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Parr, John Henry. "The secretion of the connecting peptide of proinsulin (C-peptide) in thyroid disease." Thesis, University of Liverpool, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.329437.

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Taskinen, P. (Panu). "Mapping the cellular mechanisms regulating atrial natriuretic peptide secretion." Doctoral thesis, Oulun yliopisto, 1999. http://urn.fi/urn:isbn:9514252721.

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Abstract Atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) are cardiac hormones, which are involved in the regulation of blood pressure and fluid homeostasis. The major determinant for ANP and BNP release are atrial and ventricular wall stretch, but also some vasoactive factors such as endothelin-1 (ET-1) can enhance cardiac hormone secretion. The mechanical stretch rapidly activates multiple signal transduction pathways in cardiac cells, but the cellular mechanisms mediating stretch-induced ANP secretion are still unknown. The aim of the present study was to examine the ce

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ANINI, YOUNES. "Peptide yy et peptides derives du proglucagon : liberation et effet sur la secretion pancreatique exocrine." Paris 6, 1999. http://www.theses.fr/1999PA066014.

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Le peptide yy (pyy) et les peptides derives du proglucagon (pdpg) sont liberes dans la circulation sanguine par les cellules endocrines de type l de l'ileon distal et du colon, apres l'ingestion d'un repas. Chez le rat, l'etude comparee de la liberation du pyy apres administration intraduodenale, intraileale ou intracolique d'un repas mixte (21 kj) ou de nutriments, a montre que le pyy etait libere plus rapidement et de facon plus importante apres l'administration intraduodenale, par un mecanisme indirect, prenant naissance dans l'intestin proximal, nerveux, nicotinique, impliquant la liberati

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Ng, Ming Tak. "Effects of prominsulin C-peptide and other islet peptides on beta-cell function and insulin secretion." Thesis, University of Ulster, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.554231.

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Hyperglycaemia is a significant pathophysiological feature of diabetes mellitus. It has been considered to be a cause as well as a consequence of impaired pancreatic p-cell function and insulin action. The detrimental effects of a hyperglycaemic environment encourage the non-enzymatic glycation of regulatory and functional proteins. This thesis investigated the effects of pro insulin C-peptide and other important islet peptides such as insulin, somatostatin, islet amyloid polypeptide (IAPP) as well as the gut hormone gastric inhibitory polypeptide (GIP) in both native and glycated forms on ins

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Del, Linz S. J. L. "Scanning ion conductance microscopy : modelling and approaches to studying peptide secretion." Thesis, University College London (University of London), 2011. http://discovery.ucl.ac.uk/1331878/.

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Scanning ion conductance microscopy (SICM) offers a number of benefits for both imaging and recording from biological samples. However, several fundamental issues concerning this technique, including the image resolution, remain to be clearly understood. In this thesis a model of SICM has been developed to address these issues. This model is quite general and can accommodate arbitrary geometries for both the probe and the sample surface. Model simulations using simple geometries are in good agreement with known analytical solutions and experimental data. The simulations have therefore been ext

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Higgins, Paul B. "Intestinal peptides and ethnic differences in insulin secretion." Thesis, Birmingham, Ala. : University of Alabama at Birmingham, 2006. http://www.mhsl.uab.edu/dt/2006p/higgins.pdf.

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Chahal, Sabreen. "Structural characterization of the MATα prepro-peptide secretion leader in Pichia pastoris". Scholarly Commons, 2016. https://scholarlycommons.pacific.edu/uop_etds/166.

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The methylotrophic yeast, Pichia pastoris, is the most successful and favored microbial eukaryotic expression system for the production of recombinant proteins for biopharmaceutical or industrial purposes. P. pastoris has the ability to produce foreign proteins at high levels extracellularly, and since it secretes few endogenous proteins, this ability eliminates the need for expensive purification costs. It also combines the ease of genetic manipulation with rapid growth to high cell densities and provides complex posttranslational modifications. The most commonly utilized secretion signal lea

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Meloche, Robert Mark. "The study of humoral inhibition of gastric acid secretion." Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/24862.

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Part I Inhibition of Gastric Acid Secretion Fat in the small bowel is a powerful inhibitor of gastric acid secretion. The gastric inhibitory agent(s) liberated from intestinal mucosa by the presence of fat has been named enterogastrone. Gastric inhibitory polypeptide (GIP), has been considered a candidate for enterogastrone. GIP is released into the circulation by infusion of fat into the proximal small bowel and inhibits gastric acid secretion under select experimental conditions. It has been proposed that the release of somatostatin, a potent inhibitor of acid secretion, may mediate the gas

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Yu, Julie C.-M. "Endothelin peptide secretion and receptor expression in human cultured vascular smooth muscle cells." Thesis, University of Cambridge, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242935.

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Newton, Julia L. "Changes in gastrointestinal secretion in relation to advancing age and Helicobacter pylori infection." Thesis, University of Newcastle Upon Tyne, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244553.

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Books on the topic "Peptide Secretion"

1

K, Siddle, and Hutton J. C, eds. Peptide hormone secretion: A practical approach. IRL Press at Oxford University Press, 1990.

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2

Rehfeld, Jens F., and Jens R. Bundgaard. Cellular peptide hormone synthesis and secretory pathways. Springer, 2010.

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3

Speake, Paul Frederick. In vitro stimulation of atrial natriuretic peptide secretion from Guinea Pig atria. University of Manchester, 1994.

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4

M, Polak Julia, and Bloom Stephen Robert, eds. Endocrine tumours: The pathobiology of regulatory peptide-producing tumours. Churchill Livingstone, 1985.

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5

Meeting, Endocrine Society. Brain-gut peptides and reproductive hormone secretion: Satellite of the 71st annual meeting of the Endocrine Society, June 18-19, 1989, Washington State University, Pullman, Washington. Washington State University, 1989.

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6

Mooney, Mark H. Glucagon-like peptide-1 and gastric inhibitory polypeptide: Effects of N-terminal glycation on hormone degradation, insulin secretion and antihyperglycaemic activity. The Author], 2000.

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7

1954-, Brown David R., ed. Gastrointestinalregulatory peptides. Springer-Verlag, 1993.

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A, Alemayehu, and Brown David R. 1954-, eds. Gastrointestinal regulatory peptides. Springer-Verlag, 1993.

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9

Larsson, Olof. Peptides as cotransmitters in salivary secretion: Histochemical, biochemical and functional studies of parotid and submandibular glands. Kongl. Carolinska Medico Chirurgiska Institutet, 1989.

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Larsson, Olof. Peptides as cotransmitters in salivary secretion: Histochemical, biochemical and functional studies of parotid and submandibular glands. s.n.], 1989.

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Book chapters on the topic "Peptide Secretion"

1

Vale, W., J. Spiess, J. Vaughan, et al. "Gonadal Peptide Hormones Modulating FSH Secretion." In Verhandlungen der Deutschen Gesellschaft für Innere Medizin. J.F. Bergmann-Verlag, 1987. http://dx.doi.org/10.1007/978-3-642-85460-6_92.

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Štrbák, Vladimír. "Cell Volume and Peptide Hormone Secretion." In Mechanisms and Significance of Cell Volume Regulation. KARGER, 2006. http://dx.doi.org/10.1159/000096325.

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Malandrino, Noemi, and Robert J. Smith. "Synthesis, Secretion, and Transport of Peptide Hormones." In Endocrinology. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-44675-2_3.

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Malandrino, Noemi, and Robert J. Smith. "Synthesis, Secretion and Transport of Peptide Hormones." In Endocrinology. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-27318-1_3-1.

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Malandrino, Noemi, and Robert J. Smith. "Synthesis, Secretion and Transport of Peptide Hormones." In Endocrinology. Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-27318-1_3-2.

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Barber, D. L. "Regulation of Peptide Secretion from Gastroenteric Endocrine Cells." In Gastrointestinal Regulatory Peptides. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-77814-8_4.

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Ramachandran, J., K. Nikolics, and P. H. Seeburg. "A Novel Hypothalamic Peptide Inhibitor of Prolactin Secretion." In Contraception Research for Today and the Nineties. Springer New York, 1988. http://dx.doi.org/10.1007/978-1-4612-3746-4_10.

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Mojsov, S., G. C. Weir, and J. F. Habener. "Glucagonlike peptide I (7–37) is a potent stimulator of insulin secretion." In Peptides. Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-010-9595-2_193.

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Zhang, Wan-Jiang, Shu-li Sheng, Zhi-wei Zhao, Chun-yuan Guo, Hou-xi Ai, and Jin-yong Han. "Effects of central and peripheral brain natriuretic peptide (BNP) on aldosterone secretion." In Peptides. Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-010-9066-7_21.

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Pettengill, O. S., D. H. Wurster-Hill, C. C. Cate, and G. D. Sorenson. "Morphological Growth Characteristics and Hormone Secretion of Small Cell Carcinoma of the Lung In Vitro." In Peptide Hormones in Lung Cancer. Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-82533-0_14.

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Conference papers on the topic "Peptide Secretion"

1

HASSAN, Neeran F. "USING INCRETIN IN TREATMENT OF DIABETES MELLITUS DISEASE." In IV.International Scientific Congress of Pure,Appliedand Technological Sciences. Rimar Academy, 2022. http://dx.doi.org/10.47832/minarcongress4-29.

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Incretin hormones are gut peptides secreted in response to nutrient ingestion, which play a key role in the regulation of islet function and blood glucose levels. In humans, the major incretin hormones are glucagon-like peptide (GLP)-1 and glucose- dependent insulinotropic polypeptide (GIP), and together they fully account for the incretin effect which is defined as the phenomenon whereby orally ingested glucose elicits a much greater insulin response than that obtained when glucose is infused intravenously to give identical blood glucose levels. there is evidence to suggest that impairments i

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Foster, D., B. Schach, M. Rudinsky, et al. "The Effect of Changes in the Leader Sequence of Human Protein C on Biosynthetic Processing and Gamma-Carboxylation." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643648.

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Protein C is the precursor to a serine protease in plasma which contains gamma-carboxy glutamic acid and functions as a potent anticoagulant. Protein C shows considerable structural homology with the other vitamin K-dependent coagulation factors including prothrombin, factor VII, factor IX and factor X. This homology includes the putative pro-peptide region of the prepro leader sequences for these proteins, as well as the leader sequences for gamma-carboxylated proteins from bone. Deletion mutants have been constructed in the cDNA for human protein C in order to test the possibility that the p

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Foster, D., B. Schach, M. Rudisky, et al. "The Effect of Changes in the Leader Sequence of Human Protein C on Biosynthetic Processing and Gamma-Carboxylation." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643993.

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Protein C is the precursor to a serine protease in plasma which contains gamma-carboxy glutamic acid and functions as a potent anticoagulant. Protein C shows considerable structural homology with the other vitamin K-dependent coagulation factors including prothrombin, factor VII, factor IX and factor X. Sequence analysis ofthe cDNAs for these proteins has revealedthe presence of a prepro leader sequence that contains a pre sequence or hydrophobic signal sequence and a propeptide containing a number of highly conserved amino acids. The pre region is removed from thegrowing polypeptide chain by

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Kabanikhin, S. I., D. A. Voronov, O. I. Krivorotko, A. Yu Belonog, and A. I. Ilyin. "Numerical solution of inverse problem for secretion and kinetics of C-peptide model." In 2015 International Conference on Biomedical Engineering and Computational Technologies (SIBIRCON). IEEE, 2015. http://dx.doi.org/10.1109/sibircon.2015.7361862.

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Tanable, A., Y. Yatomi, T. Ohashi, H. Oka, T. Kariya, and S. Kume. "EFFECTS OF HUMAN ATRIAL NATRIURETIC PEPTIDES ON SECRETION REACTION IN HUMAN PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644873.

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Human atrial natriuretic peptide (h-ANP) has vasodilating and natriuretic properties, and inhibits smooth muscle contraction, renal renin secretion and adrenal aldosterone release. Although Schiffrin has reported that human platelets have receptors for ANP, its effects in platelets are not established in vivo. We therefore investigated the influence of h-ANP on secretion reaction in human platelets. Eight healthy subjects, males, aged 20 to 24 years, donated blood for the study. Citrated platelet-rich plasma (PRP) was incubated with or without h-ANP at 37 C for 2.5 minutes. The samples of 0.5

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Arsenault, Jason, Enrico Ferrari, Dhevahi Niranjan, and Bazbek Davletov. "On-Demand Assembly of Macromolecules Used for the Design and Application of Targeted Secretion Inhibitors." In The Twenty-Third American and the Sixth International Peptide Symposium. Prompt Scientific Publishing, 2013. http://dx.doi.org/10.17952/23aps.2013.100.

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Sato, Kenji. "Amelioration of high fat diet-induced obesity in rat by short chain pyroglutamyl peptides in Japanese salted fermented soy paste (miso)." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/rowd7909.

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Japanese salted fermented soybean paste (miso) is used as seasonings for traditional Japanese dishes. These products still play important roles in the modern dietary habits of Japanese, while consumption of these products has decreased approximately to 30-50% of consumption since 1975. Miso is produced by a fungi (Aspergillus oryzae) starter, referred to koji. A. oryzae produces a strong protease including both endoproteinases and exopeptidases. Thus, these products contain short chain peptides in addition to free amino acids. However, little was known of their structure and biological functio

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Bacon-Baguley, Theresa, Suzanne Kendra-Franczak та Daniel Walz. "THROMBOSPONDIN SPECIFICALLY INTERACTS WITH AMINO ACID SEQUENCES WITHIN THE A α- AND B β- CHAINS OF FIBRINOGEN". У XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643822.

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Thrombospondin (TSP) is responsible for the secretion-dependent phase of platelet aggregation. The mechanism of this action is believed to be through the binding of TSP to fibrinogen, resulting in the stabilization of the platelet aggregate. It has been established that the binding of fibrinogen to the platelet surface is dependent upon peptide sequences present, respectively, in the Aa- and y-chains. We have hypothesized that the binding of TSP to fibrinogen is also dependent upon unique fibrinogen peptide sequences. To test this hypothesis we have examined the interaction of TSP and f.ih.r.i

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Huang, Ming Bo, Jennifer Y. Wu, William W. Roth, James Lillard, and Vincent C. Bond. "Abstract 2856: Secretion modification region (SMR) peptide blocks migration and invasion in human breast cancer cells." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-2856.

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Huang, Ming Bo, Jennifer Y. Wu, William W. Roth, James Lillard, and Vincent C. Bond. "Abstract 2856: Secretion modification region (SMR) peptide blocks migration and invasion in human breast cancer cells." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-2856.

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Reports on the topic "Peptide Secretion"

1

Baszler, Timothy, Igor Savitsky, Christopher Davies, Lauren Staska, and Varda Shkap. Identification of bovine Neospora caninum cytotoxic T-lymphocyte epitopes for development of peptide-based vaccine. United States Department of Agriculture, 2006. http://dx.doi.org/10.32747/2006.7695592.bard.

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The goal of the one-year feasibility study was to identify specific cytotoxic T-lymphocyte (CTL) epitopes to Neosporacaninum in the natural bovine host in order to make progress toward developing an effective peptide-based vaccine against bovine neosporosis. We tested the hypothesis that: N. caninum SRS2 peptides contain immunogenicCTLepitope clusters cross-presented by multiple bovine MHC-I and MHC-IIhaplotypes. The specific objectives were: (1) Map bovine CTLepitopes of N. caninum NcSRS-2 and identify consensus MHC-I and class-II binding motifs; and (2) Determine if subunit immunization with

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Xie, Yunhui, and Peng Pang. A Systematic Review and Network Meta-Analysis: Effect of of GLP-1 drugs on weight loss in obese people. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2022. http://dx.doi.org/10.37766/inplasy2022.6.0074.

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Review question / Objective: 1、Whether GLP-1 drugs have weight loss effect on obese people ? 2、Which GLP-1 drugs are most effective in weight loss among obese people ? Condition being studied: Obesity is an important public health issue that has been on the rise over the last decades. It calls for effective prevention and treatment. Bariatric surgery is the most effective medical therapy for weight loss in morbid obesity, but we are in need for less aggressive treatments. Glucagon-like-peptide-1 receptor agonists are a group of incretin-based drugs that have proven to be productive for obesity

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Brown Horowitz, Sigal, Eric L. Davis, and Axel Elling. Dissecting interactions between root-knot nematode effectors and lipid signaling involved in plant defense. United States Department of Agriculture, 2014. http://dx.doi.org/10.32747/2014.7598167.bard.

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Root-knot nematodes, Meloidogynespp., are extremely destructive pathogens with a cosmopolitan distribution and a host range that affects most crops. Safety and environmental concerns related to the toxicity of nematicides along with a lack of natural resistance sources threaten most crops in Israel and the U.S. This emphasizes the need to identify genes and signal mechanisms that could provide novel nematode control tactics and resistance breeding targets. The sedentary root-knot nematode (RKN) Meloidogynespp. secrete effectors in a spatial and temporal manner to interfere with and mimic multi

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Sela, Shlomo, and Michael McClelland. Investigation of a new mechanism of desiccation-stress tolerance in Salmonella. United States Department of Agriculture, 2013. http://dx.doi.org/10.32747/2013.7598155.bard.

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Low-moisture foods (LMF) are increasingly involved in foodborne illness. While bacteria cannot grow in LMF due to the low water content, pathogens such as Salmonella can still survive in dry foods and pose health risks to consumer. We recently found that Salmonella secretes a proteinaceous compound during desiccation, which we identified as OsmY, an osmotic stress response protein of 177 amino acids. To elucidate the role of OsmY in conferring tolerance against desiccation and other stresses in Salmonella entericaserovarTyphimurium (STm), our specific objectives were: (1) Characterize the invo

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Arnett, Clint, Justin Lange, Ashley Boyd, Martin Page, and Donald Cropek. Expression and secretion of active Moringa oleifera coagulant protein in Bacillus subtilis. Engineer Research and Development Center (U.S.), 2021. http://dx.doi.org/10.21079/11681/41546.

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Cationic polypeptide proteins found in the seeds of the tropical plant Moringa oleifera have coagulation efficiencies similar to aluminum and ferric sulfates without their recalcitrant nature. Although these proteins possess great potential to augment or replace traditional coagulants in water treatment, harvesting active protein from seeds is laborious and not cost-effective. Here, we describe an alternative method to express and secrete active M. oleifera coagulant protein (MO) in Bacillus subtilis. A plasmid library containing the MO gene and 173 different types of secretory signal peptides

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Christopher, David A., and Avihai Danon. Plant Adaptation to Light Stress: Genetic Regulatory Mechanisms. United States Department of Agriculture, 2004. http://dx.doi.org/10.32747/2004.7586534.bard.

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Original Objectives: 1. Purify and biochemically characterize RB60 orthologs in higher plant chloroplasts; 2. Clone the gene(s) encoding plant RB60 orthologs and determine their structure and expression; 3. Manipulate the expression of RB60; 4. Assay the effects of altered RB60 expression on thylakoid biogenesis and photosynthetic function in plants exposed to different light conditions. In addition, we also examined the gene structure and expression of RB60 orthologs in the non-vascular plant, Physcomitrella patens and cloned the poly(A)-binding protein orthologue (43 kDa RB47-like protein).

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