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Relevant bibliographies by topics / Peptidylprolyl isomerase

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Academic literature on the topic 'Peptidylprolyl isomerase'

Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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Journal articles on the topic "Peptidylprolyl isomerase"

1

Gudavicius, Geoff, Heddy Soufari, Santosh Upadhyay, Cameron D. Mackereth, and Christopher J. Nelson. "Resolving the functions of peptidylprolyl isomerases: insights from the mutagenesis of the nuclear FKBP25 enzyme." Biochemical Society Transactions 41, no. 3 (May 23, 2013): 761–68. http://dx.doi.org/10.1042/bst20130013.

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Peptidylprolyl isomerases have been implicated in chromatin regulation through their association with histones, chromatin-modifying enzymes and DNA-binding transcription factors. As with other post-translational modifications to proteins, a mechanistic understanding of the regulation of biological processes is fostered by loss-of-function studies both in vitro and in vivo. For peptidylprolyl isomerases, this can be accomplished with small-molecule inhibitors with high affinity for the isomerase active site or by mutation of amino acid residues that contribute to catalysis. In the present artic

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Fujisaki, Hiroshi, Yasushige Yonezawa, Motoyuki Shiga, Luca Maragliano, and Shin-ichi Tate. "Exploring Reaction Pathways for Peptidylprolyl-Isomerase." Biophysical Journal 112, no. 3 (February 2017): 449a. http://dx.doi.org/10.1016/j.bpj.2016.11.2407.

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Norville, Isobel H., Katherine O'Shea, Mitali Sarkar-Tyson, Suxin Zheng, Richard W. Titball, Gabriele Varani, and Nicholas J. Harmer. "The structure of a Burkholderia pseudomallei immunophilin–inhibitor complex reveals new approaches to antimicrobial development." Biochemical Journal 437, no. 3 (July 13, 2011): 413–22. http://dx.doi.org/10.1042/bj20110345.

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Mips (macrophage infectivity potentiators) are a subset of immunophilins associated with virulence in a range of micro-organisms. These proteins possess peptidylprolyl isomerase activity and are inhibited by drugs including rapamycin and tacrolimus. We determined the structure of the Mip homologue [BpML1 (Burkholderia pseudomallei Mip-like protein 1)] from the human pathogen and biowarfare threat B. pseudomallei by NMR and X-ray crystallography. The crystal structure suggests that key catalytic residues in the BpML1 active site have unexpected conformational flexibility consistent with a role

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4

Mori, Tadashi, and Takafumi Uchida. "Small Molecule Inhibitors of Peptidylprolyl cis/trans Isomerase." Current Enzyme Inhibition 6, no. 1 (February 1, 2010): 46–53. http://dx.doi.org/10.2174/157340810790712005.

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Nagaoka, Akiko, Naohiro Takizawa, Ryohei Takeuchi, Yutaka Inaba, Izumi Saito, Yoji Nagashima, Tomoyuki Saito, and Ichiro Aoki. "Possible involvement of peptidylprolyl isomerase Pin1 in rheumatoid arthritis." Pathology International 61, no. 2 (December 28, 2010): 59–66. http://dx.doi.org/10.1111/j.1440-1827.2010.02618.x.

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6

Alag, Reema, Asha Manikkoth Balakrishna, Sreekanth Rajan, Insaf A. Qureshi, Joon Shin, Julien Lescar, Gerhard Grüber, and Ho Sup Yoon. "Structural Insights into Substrate Binding by Pv FKBP35, a Peptidylprolyl cis-trans Isomerase from the Human Malarial Parasite Plasmodium vivax." Eukaryotic Cell 12, no. 4 (February 22, 2013): 627–34. http://dx.doi.org/10.1128/ec.00016-13.

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ABSTRACT The immunosuppressive drug FK506 binding proteins (FKBPs), an immunophilin family with the immunosuppressive drug FK506 binding property, exhibit peptidylprolyl cis-trans isomerase (PPIase) activity. While the cyclophilin-catalyzed peptidylprolyl isomerization of X-Pro peptide bonds has been extensively studied, the mechanism of the FKBP-mediated peptidylprolyl isomerization remains uncharacterized. Thus, to investigate the binding of FKBP with its substrate and the underlying catalytic mechanism of the FKBP-mediated proline isomerization, here we employed the FK506 binding domain (FK

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7

Yu, Liang, Abdalla J. Mohamed, Leonardo Vargas, Anna Berglöf, Greg Finn, Kun Ping Lu, and C. I. Edvard Smith. "Regulation of Bruton Tyrosine Kinase by the Peptidylprolyl Isomerase Pin1." Journal of Biological Chemistry 281, no. 26 (April 27, 2006): 18201–7. http://dx.doi.org/10.1074/jbc.m603090200.

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8

Liu, Tao, Yu Liu, Hung-Ying Kao, and Dehua Pei. "Membrane Permeable Cyclic Peptidyl Inhibitors against Human Peptidylprolyl Isomerase Pin1." Journal of Medicinal Chemistry 53, no. 6 (March 25, 2010): 2494–501. http://dx.doi.org/10.1021/jm901778v.

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9

Mori, Tadashi, Seima Itami, Tomotaka Yanagi, Yota Tatara, Mari Takamiya, and Takafumi Uchida. "Use of a Real-Time Fluorescence Monitoring System for High-Throughput Screening for Prolyl Isomerase Inhibitors." Journal of Biomolecular Screening 14, no. 4 (April 2009): 419–24. http://dx.doi.org/10.1177/1087057109333979.

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Cyclophilin is a ubiquitous peptidyl prolyl cis/trans isomerase that plays critical roles in many biological processes. A number of cyclophilin inhibitors have been designed based on the structure of the immunosuppressant cyclosporin A. To discover inhibitors that have other structures, the authors established the high-throughput screening (HTS) method using FDSS6000 real-time fluorescence detector. The inhibitors identified with this HTS showed significant correlation with direct interaction as measured by surface plasmon resonance. This high-throughput assay system is a powerful tool for the

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10

Riggs, Daniel L., Patricia J. Roberts, Samantha C. Chirillo, Joyce Cheung-Flynn, Viravan Prapapanich, Thomas Ratajczak, Richard Gaber, Didier Picard, and David F. Smith. "The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo." EMBO Journal 22, no. 5 (March 3, 2003): 1158–67. http://dx.doi.org/10.1093/emboj/cdg108.

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Dissertations / Theses on the topic "Peptidylprolyl isomerase"

1

Pang, Wen-chi Roberta. "The role of Pin1 in the pathogenesis of human hepatocellular carcinoma." Click to view the E-thesis via HKUTO, 2006. http://sunzi.lib.hku.hk/hkuto/record/B36905847.

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Pang, Wen-chi Roberta, and 彭詠枝. "The role of Pin1 in the pathogenesis of human hepatocellularcarcinoma." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B36905847.

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The Best PhD Thesis in the Faculties of Dentistry, Engineering, Medicine and Science (University of Hong Kong), Li Ka Shing Prize,2005-2006<br>published_or_final_version<br>abstract<br>Medicine<br>Doctoral<br>Doctor of Philosophy

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Cheng, Chi-wai, and 鄭智威. "Identification and characterization of PIN1 binding partners." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45199656.

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4

Chaturvedi, Vandana. "Structure and function relationship among the peptidyl prolyl cis/trans isomerases." Diss., Mississippi State : Mississippi State University, 2007. http://sun.library.msstate.edu/ETD-db/theses/available/etd-11062007-111918.

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5

Cluning, Carmel. "Steroid receptor-associated immunophilins : influence of targeted knockdown and altered expression on receptor signalling." University of Western Australia. School of Medicine and Pharmacology, 2008. http://theses.library.uwa.edu.au/adt-WU2008.0215.

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[Truncated abstract] Steroid receptors belong to the superfamily of nuclear receptors, and include the androgen receptor (AR), estrogen receptors (ER[alpha] and ER[beta], glucocorticoid receptor (GR), mineralocorticoid receptor (MR), and the progesterone receptors (PRA and PRB). Before binding ligand, the receptor undergoes biochemical and structural modifications through a series of interactions with molecular chaperones and cochaperones all within a receptor heterocomplex. The mature receptor complexes with the major chaperone Hsp90, the stabilising cochaperone p23, and one member of a group

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Tapparo, Aurélie. "Purification de protéines de liaison du myo-inositol hexakisphosphate chez l'amibe Dictyostelium discoideum." Université Joseph Fourier (Grenoble), 1998. http://www.theses.fr/1998GRE10202.

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Dans la plupart des cellules eucaryotes, l'inositol hexakisphosphate (insp#6, acide phytique) est le phosphoinositol le plus abondant. Chez l'amibe dictyostelium discoideum, la concentration d'insp#6 est de 0,7 mm et se maintient lors du cycle de differenciation de l'amibe. La fonction intracellulaire de cet inositol polyphosphate n'est pas clairement elucidee, toutefois un role regulateur de l'insp#6 dans le processus d'endocytose a recepteurs a ete propose chez les mammiferes. Un test de liaison de l'insp#6 radioactif a ete tout d'abord mis au point afin de pouvoir suivre les proteines capab

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7

Edvardsson, Anna. "Peptidyl-prolyl cis-trans Isomerases in the Chloroplast Thylakoid Lumen." Doctoral thesis, Linköping : Univ, 2007. http://www.bibl.liu.se/liupubl/disp/disp2007/med983s.pdf.

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Bilbeisi, Rana A. 1983. "Expedient synthesis of chiral poly-substituted morpholine and oxazepine derivatives for the preparation of cyclophilin A inhibitors." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111575.

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An efficient and expedient synthetic method was developed for the preparation of chiral poly-substituted morpholine and oxazepine derivatives. The method was designed in the objective of applying the synthesis to the preparation of Cyclophilin A inhibitors.<br>The stereo- and regioselective method involves the reaction of enantiopure beta-amino alcohols with alpha,beta-unsaturated aldehydes. The synthesis proceeds through three steps; i) Reductive amination, ii) N-alkylation/ N-tosylation and iii) intramolecular-haloetherification. Stereoselectivity of this last step was controlled by N-alkyl/

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9

Pernollet, Martine. "Modification de l'antigène toxine tétanique par des radicaux libres oxygénés et par des protéines à activité peptidyl-prolyl cis-trans isomérase : influence sur sa présentation à des lymphocytes T spécifiques." Université Joseph Fourier (Grenoble ; 1971-2015), 1994. http://www.theses.fr/1994GRE10238.

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L'influence du radical libre oxygene, le radical hydroxyle (oh) et des proteines a activite peptidyl-prolyl cis-trans isomerase sur le traitement de l'antigene toxine tetanique par des cellules presentatrices d'antigenes (lymphocytes b) a ete etudiee. En ce qui concerne le radical hydroxyle, sa production par des cellules de type macrophagique a ete reproduite a l'aide d'un systeme chimique. La toxine tetanique traitee par le radical oh subit un changement de conformation, et des liaisons bityrosine intramoleculaires resistantes a la proteolyse sont formees. La toxine ainsi modifiee est plus r

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10

Ando-Roussel, Kunie. "Prolyl isomerase Pin1 et la maladie d'Alzheimer." Lille 2, 2007. http://www.theses.fr/2007LIL2S018.

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La maladie d'Alzheimer (MA) est une démence neurodégénérative caractérisée neuropathologiquement par une Dégénérescence Neurofibrillaire (DNF) et des dépôts amyloïdes. La DNF est constituée de protéines Tau hyper- et anormalement phosphorylées, alors que dépôts amyloïdes sont constitués par des peptides Amyloid Beta qui sont les produits de clivages successifs du précurseur du peptide amyloïde (APP). Actuellement, les mécanismes qui conduisent à la DNF et aux dépôts amyloïdes sont encore mal connus. Récemment, Pin1 a été retrouvée dans les deux lésions de la MA. Pin1 est une peptidyl prolyl ci

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Books on the topic "Peptidylprolyl isomerase"

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Sylvie, Rivière, ed. Peptidyl-prolyl cis/trans isomerases. Oxford: Oxford University Press, 1998.

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2

Foldase enzymes catalyzing protein folding. New York: Nova Science Publishers, 2008.

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3

Nagradova, N. K. Foldases catalyzing the formation and isomerization of disulfide bonds in proteins. New York: Nova Biomedical Books, 2009.

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4

Nagradova, N. K. Foldases catalyzing the formation and isomerization of disulfide bonds in proteins. New York: Nova Biomedical Books, 2009.

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5

1947-, Guzman Norberto A., ed. Prolyl hydroxylase, protein disulfide isomerase, and other structurally related proteins. New York: Marcel Dekker, 1998.

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6

Guzman. Prolyl Hydroxylase, Protein Disulfide Isomerase and Other Structurally Related Proteins. CRC, 1997.

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7

Christophe, Dugave, ed. Cis-trans isomerization in biochemistry. Weinheim: Wiley-VCH, 2006.

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8

Dugave, Christophe. Cis-Trans Isomerization in Biochemistry. Wiley & Sons, Limited, John, 2006.

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9

Dugave, Christophe. Cis-Trans Isomerization in Biochemistry. Wiley & Sons, Incorporated, John, 2006.

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Book chapters on the topic "Peptidylprolyl isomerase"

1

Mattoo, Autar K. "[7] Peptidylprolyl cis-trans-isomerases from plant organelles." In Methods in Enzymology, 84–100. Elsevier, 1998. http://dx.doi.org/10.1016/s0076-6879(98)90009-x.

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Conference papers on the topic "Peptidylprolyl isomerase"

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Aluise, Christopher D., and Lawrence J. Marnett. "Abstract 2062: Peptidylprolyl cis/trans isomerase A1 (Pin1) is modified by lipid electrophiles generated during oxidative stress." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-2062.

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