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Journal articles on the topic 'Periarticular injection'

Author: Grafiati

Published: 2 June 2025

Last updated: 31 July 2025

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1

Bamgbade, Olumuyiwa A., Abigail M. Allen, Daniel O. Bamgbade, et al. "Periarticular Magnesium Injection Therapy Provides Pain Relief and Enables Steroid Avoidance in Sickle Cell Arthropathy Patients." SVOA Medical Research 3, no. 3 (2025): 84–91. https://doi.org/10.58624/svoamr.2025.03.010.

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Background: Sickle cell disease (SCD) is associated with arthropathy. Arthropathy pain may require periarticular injection therapy. However, steroid injections may be unsuitable for SCD patients. Alternatively, magnesium injection may provide analgesia and avoid steroid requirement. This is a study of the impact of periarticular injection therapy on pain, sleep, and walking function improvement in SCD. It studied periarticular magnesium injection versus periarticular dexamethasone injection in SCD and matched non-SCD patients. Methods: This is an observational study of twenty adults with sever

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2

Amundson, Adam W., Rebecca L. Johnson, Matthew P. Abdel, et al. "A Three-arm Randomized Clinical Trial Comparing Continuous Femoral Plus Single-injection Sciatic Peripheral Nerve Blocks versus Periarticular Injection with Ropivacaine or Liposomal Bupivacaine for Patients Undergoing Total Knee Arthroplasty." Anesthesiology 126, no. 6 (2017): 1139–50. http://dx.doi.org/10.1097/aln.0000000000001586.

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Abstract Background Multimodal analgesia is standard practice for total knee arthroplasty; however, the role of regional techniques in improved perioperative outcomes remains unknown. The authors hypothesized that peripheral nerve blockade would result in lower pain scores and opioid consumption than two competing periarticular injection solutions. Methods This three-arm, nonblinded trial randomized 165 adults undergoing unilateral primary total knee arthroplasty to receive (1) femoral catheter plus sciatic nerve blocks, (2) ropivacaine-based periarticular injection, or (3) liposomal bupivacai

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3

Yuenyongviwat, Varah, Chaturong Pornrattanamaneewong, Thitima Chinachoti, and Keerati Chareancholvanich. "Periarticular Injection with Bupivacaine for Postoperative Pain Control in Total Knee Replacement: A Prospective Randomized Double-Blind Controlled Trial." Advances in Orthopedics 2012 (2012): 1–6. http://dx.doi.org/10.1155/2012/107309.

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Background. Local periarticular injection with bupivacaine alone in TKA has not been studied. Thus, we aimed to examine the effectiveness of local periarticular injection with bupivacaine for post-operative pain control in TKA.Method. Sixty patients undergoing TKA by a single surgeon were randomly assigned into two groups in a double-blind, placebo-controlled study. In the injection group, patients received periarticular injections with 0.25% bupivacaine before wound closure; in the control group, patients received a 0.9% normal saline injection. Both groups received the same anesthetic proced

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Jiang, Xiaofeng, TaoTao Jiang, Xiaojun Qi, Pengzhou Gai, Hongliang Sun, and Guangda Wang. "Methods of hamstring muscle injection of botulinum toxin type A combined with periarticular injection after total knee arthroplasty." STEMedicine 4, no. 2 (2023): e171. http://dx.doi.org/10.37175/stemedicine.v4i2.171.

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This study aimed to report on a method for injecting botulinum toxin type A into the hamstring muscles combined with periarticular injection in total knee arthroplasty (TKA) patients. We enrolled patients who underwent elective unilateral TKA at our hospital from February 2021 to December 2021 and administered botulinum toxin type A hamstring muscle injection combined with periarticular injection. We established and reported a detailed method for this combined approach, which could provide an alternative analgesic regimen after TKA in clinical practice.

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MORALAR, Ülker, and Çağdaş PAMUK. "Periarticular Injection of Ranawat Suspension in Combination with Tranexamic Acid Reduces Bleeding and Postoperative Pain in Total Knee Arthroplasty." Acta Medica Nicomedia 5, no. 3 (2022): 120–25. http://dx.doi.org/10.53446/actamednicomedia.1146576.

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Objective: The benefits of periarticular injections of local anesthetic agents or tranexamic acid have been previously evaluated in terms of their effects on postoperative pain in a number of orthopedic studies. However, data is lacking on the efficacy of local anesthetic and tranexamic acid combinations that may be used for this purpose. We aimed to investigate the effects of periarticular injection of both tranexamic acid and Ranawat suspension on postoperative pain and bleeding in patients undergoing total knee arthroplasty. Methods: A total of 124 patients who underwent total knee ar

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Peng, Huiming, Wei Wang, Jin Lin, Xisheng Weng, Wenwei Qian, and Wenda Wang. "Local Efficacy of Corticosteroids as an Adjuvant for Periarticular Cocktail Injection in Simultaneous Bilateral Total Knee Arthroplasty: A Prospective Randomized Double-Blind Controlled Trial." Pain Research and Management 2021 (May 19, 2021): 1–8. http://dx.doi.org/10.1155/2021/5595095.

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Multimodal cocktail periarticular injections comprising corticosteroids are the most suggested therapy for postoperative discomfort and swelling following total knee arthroplasty (TKA). Nevertheless, previous findings cannot be applied to instances of unilateral total knee arthroplasty on bilateral knees. This randomized, prospective, double-blind, controlled clinical study examines the efficacy as well as safety of periarticular multimodal cocktail injection along or sans corticosteroids in certain situations. The 60 patients (120 knees) that experienced concurrent bilateral total knee arthro

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Jiang, Xiaofeng, TaoTao Jiang, Xiaojun Qi, Pengzhou Gai, Hongliang Sun, and Guangda Wang. "Comparison of the effects of botulinum toxin type A hamstring muscle injection combined with periarticular injection and simple periarticular injection on early pain and functional recovery after total knee arthroplasty." STEMedicine 4, no. 3 (2023): e177. http://dx.doi.org/10.37175/stemedicine.v4i3.177.

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Objective: This study was designed to compare the effects of hamstring muscle injection of botulinum toxin type A (BoNT/A) combined with periarticular injection to those of simple periarticular injection alone, in terms of early pain reduction and functional recovery following total knee arthroplasty (TKA). Methods: This study included 40 patients who underwent elective unilateral TKA at our hospital from February 2021 to December 2021. The patients were randomly assigned to either the experimental group (BoNT/A injection into the hamstring muscle + periarticular injection, n = 20 cases)

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8

Britten, Tyler, Jonathan D. Hughes, Yolanda Munoz Maldonado, and Kirby D. Hitt. "Efficacy of Liposomal Bupivacaine Compared with Multimodal Periarticular Injections for Postoperative Pain Control following Total Knee Arthroplasty." Journal of Knee Surgery 32, no. 10 (2018): 979–83. http://dx.doi.org/10.1055/s-0038-1675191.

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AbstractSingle-dose long-acting periarticular anesthetics have been shown to be an effective method of postoperative analgesia in total knee arthroplasty (TKA). This study retrospectively compares the efficacy of multimodal periarticular injection consisting of a combination of ropivacaine, duramorph, epinephrine, and toradol (HC) with liposomal bupivacaine (LB) periarticular injection in TKA. This study was a retrospective matched comparative chart review of two cohorts of patients who underwent TKA within a single health care system and cared for by one provider. We compared 22 patients who

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BHALLA, J., H. K. SINGH CHAWLA, T. KAUR BINDRA, G. SAHNI, T. SINGH, and K. GERA. "Is early rehabilitation after Total Knee Replacement better with periarticular cocktail of injection or epidural Ropivacaine?" Acta Orthopaedica Belgica 90, no. 4 (2024): 613–21. https://doi.org/10.52628/90.4.13753.

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TKA is routinely done orthopaedic procedure done that aims at improving the quality of patients’ life by providing pain relief, functional improvement and deformity correction. This study aims to study the efficacy and safety of a Periarticular analgesic cocktail including ropivacaine injection and epidural ropivacaine for early rehabilitation after a total knee replacement. Methods: Total of 100 patients divided into two groups, one group received epidural ropivacaine and second group given periarticular cocktail containing ropivacaine. Then postoperatively their pain score comparison using V

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10

Kurosaka, Kenji, Sachiyuki Tsukada, Hiroyuki Ogawa, et al. "Addition of corticosteroid to periarticular injections reduces postoperative pain following total hip arthroplasty under general anaesthesia: a double-blind randomized controlled trial." Bone & Joint Journal 102-B, no. 10 (2020): 1297–302. http://dx.doi.org/10.1302/0301-620x.102b10.bjj-2020-0428.r1.

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Aims Although periarticular injection plays an important role in multimodal pain management following total hip arthroplasty (THA), there is no consensus on the optimal composition of the injection. In particular, it is not clear whether the addition of a corticosteroid improves the pain relief achieved nor whether it is associated with more complications than are observed without corticosteroid. The aim of this study was to quantify the safety and effectiveness of cortocosteroid use in periarticular injection during THA. Methods We conducted a prospective, two-arm, parallel-group, randomized

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11

Joy, Dijo P., Samson Samuel E., and P. S. John. "Comparison of effectiveness of intraoperative subperiosteal versus periarticular analgesic cocktail injection for post operative analgesia in patients undergoing total knee arthroplasty." International Journal of Research in Orthopaedics 10, no. 3 (2024): 599–605. http://dx.doi.org/10.18203/issn.2455-4510.intjresorthop20241111.

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Background: Early postoperative pain management is pivotal in patients undergoing Total knee arthroplasty. The advantage of Local infiltration analgesia is its ability to provide control of pain without interfering with motor strength of the lower extremity, thereby allowing early mobilization of patients. This study compares the effectiveness of local analgesic cocktail injection given through subperiosteal vs. periarticular routes. Methods: The study included 30 patients admitted for primary total knee arthroplasty. They were grouped into two groups based on different injection sites. Group

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Li, Sean S., Suellen S. Li, and Reid A. Abrams. "Heterotopic ossification after local steroid injection." BMJ Case Reports 13, no. 12 (2020): e235371. http://dx.doi.org/10.1136/bcr-2020-235371.

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Pachydermodactyly (PDD) is a rare, benign disease associated with progressive swelling of the periarticular soft tissue of phalangeal hand joints typically treated with local steroid injections. We present a case of a 37-year-old man with PDD treated with local steroid injections. He later developed heterotopic ossification and para-articular calcifications in the injection sites. Heterotopic ossification is not associated with PDD nor is it a recognised complication of local steroid injections. This is the first case in literature of heterotopic ossification occurring after local steroid inje

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13

Mishra, Bibhuti Nath, Joydeep Banerjee Chowdhury, Rajeev Raman, Dipmalya Chakraborty, and Tanmoy Karmakar. "Effectiveness of Periarticular Infiltration of the Knee during Total Knee Arthroplasty for Postoperative Pain Management." Europasian Journal of Medical Sciences 3, no. 2 (2021): 24–28. http://dx.doi.org/10.46405/ejms.v3i2.341.

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Background: Different treatment regimens of analgesia, nerve blocks and epidurals are used for pain relief in Total Knee Arthroplasty (TKA). Local infiltration analgesia (LIA) is one of the modalities in which a cocktail combination of different medicines is infiltrated locally into the capsule, surrounding tissues or intraarticular joint space. This study aims to analyze the effectiveness of periarticular injection of combination drugs (Bupivacaine, Ketorolac and Morphine) during TKA for postoperative pain management. Methods: Total of 150 patients who underwent primary unilateral TKA w

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Heebthamai, Danai, Noppadol Aegakkatajit, Thanainit Chotanaphuti, and Saradej Khuangsirikul. "RECOVERY OF HEMOGLOBIN LEVEL FOLLOWING TOTAL KNEE ARTHROPLASTY WITH PERIARTICULAR EPINEPHRINE INJECTION." Journal of Southeast Asian Medical Research 3, no. 1 (2019): 32–39. http://dx.doi.org/10.55374/jseamed.v3i1.47.

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Background: Anemia is one of the common complications occurring after total knee arthroplasty (TKA). A periarticular epinephrine injection could reduce intraoperative blood loss after TKA. However, the duration of hemoglobin recovery to preoperative level remains uncertain. The hypothesis was based on the concept that epinephrine affects vasoconstriction and reduces blood loss. This study was conducted to compare the duration of hemoglobin recovery to preoperative level between periarticular epinephrine injection and periarticular nonepinephrine injection groups and postoperative blood transfu

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Hirose, Hitoshi, Hiroyasu Ogawa, Kazu Matsumoto, and Haruhiko Akiyama. "Periarticular injection of tranexamic acid promotes early recovery of the range of knee motion after total knee arthroplasty." Journal of Orthopaedic Surgery 27, no. 3 (2019): 230949901986469. http://dx.doi.org/10.1177/2309499019864693.

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Purpose: Tranexamic acid (TXA) is a commonly used compound that reduces postoperative blood loss. Periarticular injection of TXA is a recently reported procedure with some advantages such as cost-effectiveness and the ease of performance over an intravenous or topical administration. However, its association with functional recovery remains unclear. This study aimed to examine the effect of periarticular injection of TXA on early postoperative recovery of knee functionality after total knee arthroplasty (TKA). Methods: Eighty-four patients who underwent primary unilateral TKA from February 201

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Bogdanov, E. I., T. G. Sakovets, and R. A. Altunbaev. "Efficiency of intra-articular, periarticular, local intramuscular and perineural injection therapy in the treatment of nociceptive and neuropathic pain syndromes." Kazan medical journal 96, no. 4 (2015): 571–77. http://dx.doi.org/10.17750/kmj2015-571.

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Diseases of the musculoskeletal system are accompanied by nociceptive, neuropathic pain which is, in addition to kinesitherapy, physical therapy and acupuncture, widely treated using the local injection therapy. This treatment method is commonly used by physicians of different specialties for about 100 years and includes intra-articular, periarticular, perineural, intramuscular administration of different medicines, homeopathic remedies or medical devices. Hyaluronic acid salts, nonsteroid anti-inflammatory drugs, glucocorticosteroids, local anesthetics, vitamin B12, botulinum toxin A medicati

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Martin, W., S. Albano-Aluquin, S. Banks, and N. Olsen. "POS1598-HPR TEACHING AND CLINICAL OUTCOMES OF A NOVEL FELLOWS’ INJECTION CLINIC." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1175.1–1175. http://dx.doi.org/10.1136/annrheumdis-2023-eular.1435.

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BackgroundThe skills of performing joint/periarticular injections by rheumatology fellows are learned during training but achieving the necessary level of expertise can be challenging if the rotations lack dedicated skills teaching. There is also a paucity of literature reporting how injection proficiency evolves and how the type and number of procedures can affect performance.ObjectivesTo combat these issues and enhance fellow training and patient outcomes, we started an exclusive fellows’ monthly injection clinic and assessed the learners’ progress by analyzing their proficiency scores (PS)

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18

Hongnaparak, Theerawit, Khanin Iamthanaporn, Pakjai Tuntarattanapong, and Varah Yuenyongviwat. "Efficacy of a Combined Intramedullary, Periarticular Injection, and Intraarticular Tranexamic Acid Application on Postoperative Bleeding in Total Knee Arthroplasty: A Retrospective Case-Matched Study." Advances in Orthopedics 2022 (December 10, 2022): 1–5. http://dx.doi.org/10.1155/2022/9175189.

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Background. Topical tranexamic acid (TXA) has been widely used to reduce postoperative blood loss following total knee replacement (TKA). This study aimed to evaluate the effect of combined intramedullary, periarticular injection, and intraarticular TXA application in patients who underwent TKA as compared to those who did not. Methods. This was a retrospective case-matched study of 111 patients. We evaluated the transfusion rate and postoperative drainage of 56 patients who underwent TKA using combined topical tranexamic acid application (directly pushed into the femoral intramedullary canal

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Teng, Yuanjun, Jin Jiang, Shaolong Chen, et al. "Periarticular multimodal drug injection in total knee arthroplasty." Knee Surgery, Sports Traumatology, Arthroscopy 22, no. 8 (2013): 1949–57. http://dx.doi.org/10.1007/s00167-013-2566-0.

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Chaumeron, Arnaud, Daniel Audy, Pierre Drolet, Martin Lavigne, and Pascal-André Vendittoli. "Periarticular Injection in Knee Arthroplasty Improves Quadriceps Function." Clinical Orthopaedics and Related Research® 471, no. 7 (2013): 2284–95. http://dx.doi.org/10.1007/s11999-013-2928-4.

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Heidari, Nima, Tanja Kraus, Stefan Fischerauer, Norbert Tesch, and Annelie Weinberg. "Do the Presence of Pathologic Changes and the Level of Operator Experience Alter the Rate of Intra-Articular Injection of the First Metatarsophalangeal Joint?" Journal of the American Podiatric Medical Association 103, no. 3 (2013): 204–7. http://dx.doi.org/10.7547/1030204.

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Background: Injections, punctures, and aspirations of the first metatarsophalangeal joint are common interventions. Accurate intra-articular placement of the needle is a prerequisite for the achievement of desirable results and the avoidance of complications. We evaluated the rate of successful intra-articular injections and the influence of the degree of operator experience in achieving this success. Methods: A total of 106 cadaveric metatarsophalangeal joints were injected with a methylene blue–containing solution and subsequently dissected to distinguish intra-articular from periarticular i

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Broome, Brandon. "Periarticular Injection With Liposomal Bupivicaine, Is Technique the Key?" Journal of Arthroplasty 29, no. 11 (2014): 2233. http://dx.doi.org/10.1016/j.arth.2014.08.009.

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Webb, Bradley T., J. Reid Spears, Langan S. Smith, and Arthur L. Malkani. "Periarticular injection of liposomal bupivacaine in total knee arthroplasty." Arthroplasty Today 1, no. 4 (2015): 117–20. http://dx.doi.org/10.1016/j.artd.2015.09.001.

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Habib, George, Fahed Sakas, Suheil Artul, and Fadi Khazin. "The Effect of Periarticular Injection of Methylprednisolone Acetate in Patients with Primary Osteoarthritis of the Proximal Interphalangeal Joints: A Case Controlled Study." Pain Research and Treatment 2018 (November 14, 2018): 1–4. http://dx.doi.org/10.1155/2018/7561209.

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Backgrounds. Primary osteoarthritis of the proximal interphalangeal joints (PIPJ) is a common entity. It could be associated with local pain that has no effective treatment. Local subcutaneous periarticular injection of methylprednisolone acetate (MPA) was evaluated in a prospective case-control study. Methods. Patients with painful osteoarthritis of the PIPJ for more than 1 month not responding to nonsteroidal meds were prospectively recruited. Radiographic, demographic, clinical, and lab parameters were documented. Visual analogue scale (VAS) was documented regarding the level of PIPJ pain p

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Dalury, David F. "Periarticular Injection Technique to Enhance Pain Relief After Knee Arthroplasty." JBJS Essential Surgical Techniques 4, no. 2 (2014): e7. http://dx.doi.org/10.2106/jbjs.st.n.00001.

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26

Busch, Constant A., Benjamin J. Shore, Rakesh Bhandari, et al. "Efficacy of Periarticular Multimodal Drug Injection in Total Knee Arthroplasty." Journal of Bone & Joint Surgery 88, no. 5 (2006): 959–63. http://dx.doi.org/10.2106/jbjs.e.00344.

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BUSCH, CONSTANT A., BENJAMIN J. SHORE, RAKESH BHANDARI, et al. "EFFICACY OF PERIARTICULAR MULTIMODAL DRUG INJECTION IN TOTAL KNEE ARTHROPLASTY." Journal of Bone and Joint Surgery-American Volume 88, no. 5 (2006): 959–63. http://dx.doi.org/10.2106/00004623-200605000-00005.

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Chaumeron, Arnaud, Daniel Audy, Pierre Drolet, Martin Lavigne, and Pascal-André Vendittoli. "Erratum to: Periarticular Injection in Knee Arthroplasty Improves Quadriceps Function." Clinical Orthopaedics and Related Research 471, no. 6 (2013): 2042. http://dx.doi.org/10.1007/s11999-013-2970-2.

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CHANDY, KURIAN, and PHILIP FANAPOUR. "SYMPTOMATIC BRADYCARDIA FOLLOWING PERIARTICULAR INJECTION: A CASE OF BUPIVACAINE TOXICITY." CHEST 164, no. 4 (2023): A2716—A2717. http://dx.doi.org/10.1016/j.chest.2023.07.1796.

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Tsukada, Sachiyuki, Kenji Kurosaka, Tetsuyuki Maeda, Akihiro Iida, Masahiro Nishino, and Naoyuki Hirasawa. "Early stage periarticular injection during total knee arthroplasty may provide a better postoperative pain relief than late-stage periarticular injection: a randomized-controlled trial." Knee Surgery, Sports Traumatology, Arthroscopy 27, no. 4 (2018): 1124–31. http://dx.doi.org/10.1007/s00167-018-5140-y.

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Acharya, Priya Ranjan. "Effectiveness of Periarticular Cocktail Injection in Pain Management of Patients Undergoing Total Knee Arthroplasty." Odisha Journal of Orthopaedics and Trauma 3, no. 1 (2022): 10–13. http://dx.doi.org/10.13107/ojot.2022.v03i01.026.

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Introduction: Total knee arthroplasty is a procedure that can improve quality of life, and it is performed in increasing numbers every year because of the increase in the elderly population due to improved medical technology. However, the problem is that patients avoid this operation because of postoperative pain, which affects patient satisfaction and delays recovery and rehabilitation. There are many modalities to improve operative pain control, such as femoral nerve blocks, epidural anaesthesia, and periarticular injections. These modalities have been shown to reduce post-operative pain and

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Trindade, Irene. "Infiltração Peri-Articular de Corticosteróides na Abordagem da Patologia Músculo- Esquelética em Medicina Geral e Familiar: Uma Revisão Sistemática." Acta Médica Portuguesa 28, no. 5 (2015): 652. http://dx.doi.org/10.20344/amp.6127.

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<strong>Introduction:</strong> Periarticular corticosteroid injection utilization by General Practitioners treating musculoskeletal disease in primary health care system is internationally acknowledged. This article aims at analyzing this evidence and contributing to the discussion of a potential development of the technique in Portugal.<br /><strong>Material and Methods:</strong> Qualitative analysis of randomized control trials, cost-effectiveness studies, cross-sectional studies, retrospective cohort studies and observational studies, using PRISMA model. Data S

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YUE, De-bo, Bai-liang WANG, Kun-peng LIU, and Wan-shou GUO. "Efficacy of multimodal cocktail periarticular injection with or without steroid in total knee arthroplasty." Chinese Medical Journal 126, no. 20 (2013): 3851–55. http://dx.doi.org/10.3760/cma.j.issn.0366-6999.20131389.

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Background Multimodal cocktail periarticular injection (MCPI) with a large volume of low concentration local anesthetics, adrenaline, and anti-inflammatory agents such as non-steroidal anti-inflammatory drug or steroids have shown good pain control and improvement in range of motion after surgery. This study compares the efficacy of pain control after total knee arthroplasty, using multimodal cocktail periarticular injection with steroid or without steroid. Methods This is a prospective, double-blinded, randomized and control study. Seventy-two patients with osteoarthritis that met clinical cr

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Pathonsamit, Chompunoot, Pruk Chaiyakit, and Ittiwat Onklin. "Side-Effect Profiles And Efficacy Of Low Dose Intrathecal Morphine Combine With Periarticular Injection In Elective Primary Unilateral Total Knee Arthroplasty." Orthopaedic Journal of Sports Medicine 8, no. 5_suppl5 (2020): 2325967120S0009. http://dx.doi.org/10.1177/2325967120s00099.

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Background: Total knee arthroplasty (TKA) is concerned as a severe postoperative pain procedure. Intrathecal morphine provides good analgesia but has many side effects such as nausea, vomiting, pruritus and respiratory depression. Appropriate postoperative pain control strategy with lower side effect is still challenging. We combined periarticular injection(PI) as a multimodal analgesia with intrathecal morphine in order to decrease intrathecal morphine dosage and lower side effects. Objective: To determine side-effect profiles and efficacy of 0.1 mg and 0.2 mg intrathecal morphine combine wit

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Shin, Seong Kee, Do Kyung Lee, Dae Won Shin, Tae Hoon Yum, and Jun-Ho Kim. "Local Infiltration Analgesia Versus Femoral Nerve Block for Pain Control in Anterior Cruciate Ligament Reconstruction: A Systematic Review With Meta-analysis." Orthopaedic Journal of Sports Medicine 9, no. 11 (2021): 232596712110506. http://dx.doi.org/10.1177/23259671211050616.

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Background: Anterior cruciate ligament reconstruction (ACLR) is often performed on an outpatient basis; thus, effective pain management is essential to improving patient satisfaction and function. Local infiltration analgesia (LIA) and femoral nerve block (FNB) have been commonly used for pain management in ACLR. However, the comparative efficacy and safety between the 2 techniques remains a topic of controversy. Purpose: To compare pain reduction, opioid consumption, and side effects of LIA and FNB after ACLR. Study Design: Systematic review; Level of evidence, 3. Methods: A systematic search

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Atik, O. Şahap, Laszlo Rudolf Hangody, Sualp Turan, Fatih İlker Can, and Özlem Orhan. "Is periarticular injection superior to intraarticular injection to reduce postoperative pain following total knee arthroplasty?" Joint Diseases and Related Surgery 34, no. 1 (2022): 1–2. http://dx.doi.org/10.52312/jdrs.2023.57909.

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Choi, Ho-Rim, Jong-Seok Park, and Byung-Ill Lee. "The Effect of Intraoperative Periarticular Local Injection in Total Knee Arthroplasty." Journal of the Korean Orthopaedic Association 43, no. 5 (2008): 638. http://dx.doi.org/10.4055/jkoa.2008.43.6.638.

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IKEUCHI, Masahiko. "Postoperative Pain Management with Periarticular Cocktail Injection in Joint Replacement Surgery." JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA 33, no. 3 (2013): 381–85. http://dx.doi.org/10.2199/jjsca.33.381.

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Tammachote, Nattapol, Supakit Kanitnate, Sudsayam Manuwong, Thanasak Yakumpor, and Phonthakorn Panichkul. "Is Pain After TKA Better with Periarticular Injection or Intrathecal Morphine?" Clinical Orthopaedics and Related Research 471, no. 6 (2013): 1992–99. http://dx.doi.org/10.1007/s11999-013-2826-9.

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Lombardo, Daniel J., Teresa Potter, Gregory Tocks, et al. "Periarticular injection versus placebo in total knee arthroplasty with intrathecal morphine." Knee 54 (June 2025): 122–27. https://doi.org/10.1016/j.knee.2025.02.004.

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Bourne, I. H. J. "Local Corticosteroid Injection Therapy." Acupuncture in Medicine 16, no. 2 (1998): 95–102. http://dx.doi.org/10.1136/aim.16.2.95.

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The advent of injectable insoluble corticosteroids in 1952 allowed steroid injected at tender spots to remain long enough to destroy affected tissue and allow regrowth of normal fibres. Injection of small doses of triamcinolone and lignocaine directly into trigger points has proved a success in relieving chronic pain associated with localised fibromyalgic lesions in 70% of the author's personal series of 840 patients. Each steroid injection given in this series has been recorded with a diagram of its exact position. This has shown that recurrence of pain is very rarely associated with recurren

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Bowen, Joseph, Joshua P. Rainey, Jonathan Linthicum, Brenna E. Blackburn, and Lucas A. Anderson. "Liposomal bupivacaine versus standard periarticular injections in total hip and knee arthroplasty: a prospective, randomized non-inferiority trial." SICOT-J 11 (2025): 17. https://doi.org/10.1051/sicotj/2025012.

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Introduction: Numerous multimodal pain protocols have been developed to optimize pain control, reduce narcotics consumption, and shorten the length of stay after total hip and knee arthroplasty (THA/TKA). Liposomal bupivacaine (LB) has been postulated to reduce narcotic requirements after arthroplasty but is not without additional cost. The aim of this study was to determine if the addition of LB to our standard periarticular injection would improve postoperative pain and shorten the length of stay in patients undergoing TKA or THA. Methods: We performed a prospective randomized, blinded non-i

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Song, Eun-Kyoo, Jong-Keun Seon, Sang-Jin Park, Young-Jin Kim, Dam-Seon Lee, and Hyun-Kee Yang. "Short Term Analgesic Effects of Intraoperative Periarticular Injection in Total Knee Arthroplasty." Journal of the Korean Orthopaedic Association 43, no. 5 (2008): 625. http://dx.doi.org/10.4055/jkoa.2008.43.5.625.

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Coronel, P., M. Gimeno, and R. J. Petrella. "THU0566 Management of Ankle Sprain with Single Periarticular Injection of Sodium Hyaluronate." Annals of the Rheumatic Diseases 73, Suppl 2 (2014): 378.2–378. http://dx.doi.org/10.1136/annrheumdis-2014-eular.4875.

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Grosso, Matthew J., Taylor Murtaugh, Akshay Lakra, et al. "Adductor Canal Block Compared with Periarticular Bupivacaine Injection for Total Knee Arthroplasty." Journal of Bone and Joint Surgery 100, no. 13 (2018): 1141–46. http://dx.doi.org/10.2106/jbjs.17.01177.

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Goytizolo, Enrique A., Yi Lin, David H. Kim, et al. "Addition of Adductor Canal Block to Periarticular Injection for Total Knee Replacement." Journal of Bone and Joint Surgery 101, no. 9 (2019): 812–20. http://dx.doi.org/10.2106/jbjs.18.00195.

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Ng, Fu-Yuen, Jacobus Kwok-Fu Ng, Kwong-Yuen Chiu, Chun-Hoi Yan, and Chi-Wing Chan. "Multimodal Periarticular Injection Vs Continuous Femoral Nerve Block After Total Knee Arthroplasty." Journal of Arthroplasty 27, no. 6 (2012): 1234–38. http://dx.doi.org/10.1016/j.arth.2011.12.021.

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Martin, Nikhil Joseph, Vinod Padmanabhan, and Johny Joseph Pindis. "Efficacy of Periarticular Cocktail Injection in Rheumatoid Patients Undergoing Total Knee Replacement." Indian Journal of Orthopaedics 54, no. 6 (2020): 811–22. http://dx.doi.org/10.1007/s43465-020-00230-3.

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Choi, Jang-Seok, Jung-Han Kim, Heui-Chul Gwak, Jung-won Kim, and Young Kyoung Min. "Pain Control after Total Hip Replacement Arthroplasty Using Periarticular Multimodal Drug Injection." Journal of the Korean Hip Society 22, no. 4 (2010): 273. http://dx.doi.org/10.5371/jkhs.2010.22.4.273.

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Galimba, Jhunne. "Promoting the Use of Periarticular Multimodal Drug Injection for Total Knee Arthroplasty." Orthopaedic Nursing 28, no. 5 (2009): 250–54. http://dx.doi.org/10.1097/nor.0b013e3181b822ed.

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