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1

Elsaka, O., M. A. NOURELDEAN, M. A. GAMIL, M. T. GHAZALI, AL-RAZIK A. H. ABD, and D. HISHAM. "A REVIEW ON PERICARDIAL EFFUSION." Asian Journal of Advances in Research 12, no. 1 (2022): 25–40. https://doi.org/10.5281/zenodo.7633723.

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Background: The collection of extra fluid in the pericardial sac surrounding the heart is referred to as a pericardial effusion. The pericardial sac contains between 15 and 50 milliliters (mL) of serous fluid in a healthy person. Infectious organisms or malignant cells may be present in this fluid, which can be transudative, exudative, or sanguineous. Infection, inflammation, or direct blood filling of the pericardial sac from a defect in the myocardium (iatrogenic or traumatic injury or heart wall rupture) or backfilling from an ascending aortic dissection that dissects into the pericard
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2

Saku, Kosuke, Keisuke Yamamoto, Hironori Inoue, and Masahiro Ueno. "A Rare Case of Pericardial Effusion in a Patient with Silicosis." Case Reports in Cardiology 2019 (June 9, 2019): 1–4. http://dx.doi.org/10.1155/2019/5068580.

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Silicosis is an occupational lung disorder caused by inhalation of silica dust. It not only causes respiratory disorders but also affects other organs. We report an extremely rare case of silicosis complicated by pericarditis in an 83-year-old male. He had been working as a coal miner and was diagnosed with silicosis at the age of 63. Because he had experienced repeated pericardial effusions, he was referred for a surgical pericardial biopsy to elucidate the cause of his repeated pericardial effusion and to perform pericardial fenestration. Thoracoscopic surgery was performed. The pericardium
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3

Imazio, Massimo, Marzia Colopi, and Gaetano Maria De Ferrari. "Pericardial diseases in patients with cancer: contemporary prevalence, management and outcomes." Heart 106, no. 8 (2020): 569–74. http://dx.doi.org/10.1136/heartjnl-2019-315852.

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Neoplastic pericardial effusion is a common and serious manifestation of advanced malignancies. Lung and breast carcinoma, haematological malignancies, and gastrointestinal cancer are the most common types of cancer involving the pericardium. Pericardial involvement in neoplasia may arise from several different pathophysiological mechanisms and may be manifested by pericardial effusion with or without tamponade, effusive-constrictive pericarditis and constrictive pericarditis. Management of these patients is a complex multidisciplinary problem, affected by clinical status and prognosis of pati
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Chinchilla-Trigos, Luis Alberto, Edgardo Jiménez-Fuentes, Abelardo Meneses-García, and Mariana Cobos-Ortiz. "Treatment of Pericardial Effusion in Cancer Patients." Cancer Plus 2, no. 4 (2020): 7. http://dx.doi.org/10.18063/cp.v2i4.353.

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Pericardial effusion is the most common cardiac complication in cancer patients. Lung and breast cancers are the most common solid tumors associated with pericardial effusion. Multimodal tumor therapy improves the overall survival rate and reduces tumor complications. However, these patients need individualized treatment. This paper describes the treatment experience of pericardial effusion, from its pathophysiology, the correct classification of pericardial effusion related to malignant tumor, malignant pericardial effusion or pericardial cancer, to the methods of diagnosis and treatment. The
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5

Kalogeraki, Alexandra, George Lazopoulos, Georgios Z. Papadakis, et al. "Cytology of Pericardial Effusion due to Malignancy." Romanian Journal Of Internal Medicine 54, no. 3 (2016): 179–83. http://dx.doi.org/10.1515/rjim-2016-0026.

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Abstract Background. Malignant pericardial effusion occurs in one tenth of all cancers. It is a very serious disorder that is mainly a secondary process due to metastasis because primary neoplasms of the pericardium such as mesotheliomas, sarcomas being exceedingly rare. Pericardial effusions with a cardiac tamponade constitute a surgical emergency and the pericardiocentesis represents the first class therapeutic recommendation. Pericardial effusion specimens are uncommon and to the best of our knowledge the current study is the largest systematic evaluation of pericardial fluid cytology perfo
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Al-Mosawi, Aamir Jalal. "Symptomatic Childhood Uremic Pericardial Effusion: An Echocardiography Image." Cardiology Research and Reports 2, no. 2 (2020): 01–02. http://dx.doi.org/10.31579/2692-9759/010.

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Large childhood symptomatic pericardial effusion demanding pericardio-centesis and pericardial drainage is rare and symptomatic childhood uremic pericardial effusion is even rarer. The aim of this paper is to report the rare occurrence of childhood uremic symptomatic pericardial effusion. A seven year old boy with the most extreme form of end-stage renal disease (anuric with no renal function). The patient developed large childhood symptomatic pericardial effusion which was diagnosed by echocardiography.
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Al-Mosawi, Aamir. "Symptomatic Childhood Uremic Pericardial Effusion: An Echocardiography Image." Cardiology Research and Reports 2, no. 2 (2020): 01–02. http://dx.doi.org/10.31579/2690-1897/010.

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Large childhood symptomatic pericardial effusion demanding pericardio-centesis and pericardial drainage is rare and symptomatic childhood uremic pericardial effusion is even rarer. The aim of this paper is to report the rare occurrence of childhood uremic symptomatic pericardial effusion. A seven year old boy with the most extreme form of end-stage renal disease (anuric with no renal function). The patient developed large childhood symptomatic pericardial effusion which was diagnosed by echocardiography.
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8

Kokulenko, Kira V., Anna V. Goncharova, and Vladislav A. Kostalev. "Risk factors for the occurrence and development of pericardial effusions in dogs." Veterinariya, Zootekhniya i Biotekhnologiya 8, no. 117 (2023): 35–41. http://dx.doi.org/10.36871/vet.zoo.bio.202308004.

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Pericardial effusion is an accumulation of fluid in the pericardial cavity, which can lead to cardiac tamponade – a life–threatening condition of the animal. In cardiac tamponade, the intrapericardial pressure exceeds the diastolic filling pressure of the right ventricle. This, in turn, leads to compression of the right chambers of the heart during diastole, which prevents normal systemic venous return. The consequence is a decrease in the stroke volume of the heart and a violation of cardiac output. According to available literature data, the most common causes of pericardial effusion in dogs
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9

Bagardi, Mara, Giulia Drago, Paolo Ferrari, Jacopo Riva, and Melania Moioli. "Acute severe pericarditis secondary to rodenticide intoxication in a dog." Open Veterinary Journal 12, no. 5 (2022): 728. http://dx.doi.org/10.5455/ovj.2022.v12.i5.18.

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Background: Pericardial effusions are well described in dogs, however their association with rodenticide intoxication in the canine population is not widely described. Case Description: An adult mixed breed dog was presented for one-day history of anorexia and cough. Thoracic radiographs revealed moderate generalized cardiomegaly with globoid shaped cardiac silhouette and mild bilateral pleural effusion. Echocardiography showed mild tamponating pericardial effusion and diffuse severe thickened pericardium. Compete blood count (CBC) and blood chemistry at presentation were not specific. A coagu
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10

Dr., Abubaker*, Moid Khan Dr., and Syed Hassan Dr. "CASE REPORT OF PRIMARY ADENOCARCINOMA OF LUNG PRESENTING AS CARDIAC TAMPONADE IN 35 YEAR OLD NON SMOKING FEMALE." World Journal of Pharmaceutical Science and Research 4, no. 2 (2025): 830–34. https://doi.org/10.5281/zenodo.15274658.

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Lung cancer is often the most diagnosed carcinoma and leading cause of cancer related death worldwide. In India lung carcinoma makes 5.9% of all cancer and accounts for 8.9% of deaths.<sup>[1]</sup> This is a case report of a non smoker female who presented to emergency with cardiac tamponade with no presiding symptoms turned out to be a secondary cardiac tamponade with primary lung carcinoma. The etiology of pericardial involvement in cancer may be complicated. Secondary pericardial effusion occurs more frequently than primary pericardial effusion does. Any cancer can affect the pericardium,
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11

Bashir, Hamid, Monika Metzger, Matt Krasin, Sue Kaste, Scott Howard, and Melissa M. Hudson. "Pericardial Involvement in Newly Diagnosed Children and Adolescents with Pediatric Hodgkin’s Disease at a Single Children’s Cancer Hospital." Blood 106, no. 11 (2005): 4645. http://dx.doi.org/10.1182/blood.v106.11.4645.4645.

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Abstract Background: Because most cases are clinically silent, incidence, clinical course and outcome of pericardial involvement in Hodgkin disease are unknown. Methods: Records of all 274 newly diagnosed Hodgkin disease patients treated at our institution between 1991 and 2004 were reviewed. Cases were selected on the basis of pericardial involvement with focal thickening or nodularity at the time of presentation identified by CT and/or pericardial effusion on echocardiogram. Variables noted, in addition to basic demographic data, were stage, histologic subtype, clinical presentation, treatme
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12

D'Souza, Melroy S., Kaitlin Shinn, and Anup D. Patel. "Posttraumatic Subacute Effusive-Constrictive Pericarditis After a Motor Vehicle Accident." Texas Heart Institute Journal 47, no. 3 (2020): 233–35. http://dx.doi.org/10.14503/thij-19-7002.

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Effusive-constrictive pericarditis is typically caused by tuberculosis or other severe inflammatory conditions that affect the pericardium. We report a case of effusive-constrictive pericarditis consequent to a motor vehicle accident. A 32-year-old man with gastroesophageal reflux disease presented with severe substernal chest pain of a month's duration and dyspnea on exertion for one week. Echocardiograms revealed a moderate pericardial effusion, and the diagnosis was subacute effusive-constrictive pericarditis. After thorough tests revealed nothing definitive, we learned that the patient had
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13

Saputra, Gede Ardi, Kesih Kalua, Herick Alvenus Willim, and Eva Lydia Munthe. "Lung Adenocarcinoma Complicated By Hydropneumothorax And Pericardial Effusion With Impending Cardiac Tamponade: A Rare Case Report From A Rural Hospital In Ketapang Regency." Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan 18, no. 2 (2024): 243–51. https://doi.org/10.33533/jpm.v18i2.9259.

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Lung adenocarcinoma is often associated with pulmonary complications such as hydropneumothorax and pleural effusion, and cardiac complications such as cardiac tamponade and pericardial effusion, but are very rare. In our case, a 52-year-old woman presented with worsening shortness of breath for 1 month. The patient underwent thoracentesis after chest X-ray showed right pleural effusion. Pleural fluid cytology showed pulmonary adenocarcinoma. Chest CT scan showed hydropneumothorax and pericardial effusion. In conclusion, pleural effusion is common in lung malignancies. In this case, hydropneumo
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14

BS, Forest Riekhof, and Farzana Hoque. "Idiopathic Pericarditis Leading to Hemorrhagic Pericardial Effusion- A Case Report and Review." Journal of Medicine 25, no. 1 (2024): 87–89. http://dx.doi.org/10.3329/jom.v25i1.70533.

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Pericardial effusion presentation is a large spectrum that can vary from asymptomatic to cardiac tamponade. It is a relatively common syndrome and has a diverse set of etiologies including infections, malignancy, radiation/iatrogenic, pericardial injury, metabolic disturbances, endocrine disease, connective tissue disease, autoimmune disorders, trauma, or idiopathic. Pericardial drainage is recommended in most large pericardial effusions or those causing cardiac tamponade. Pericardial fluid can be either purulent, serous, serosanguinous, or hemorrhagic. In the case of hemorrhagic effusion, the
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15

Samuels, Louis E., Philbert Y. Van, Douglas E. Gladstone, and Marian M. Haber. "Malignant Pericardial Effusion--An Uncommon Complication of Multiple Myeloma: Case Report." Heart Surgery Forum 8, no. 2 (2005): 87. http://dx.doi.org/10.1532/hsf98.20041153.

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Multiple myeloma is a condition usually associated with lesions of the skeleton. However, under rare circumstances, the malignant plasma cells may infiltrate the pericardium, resulting in an effusion. If left untreated, the abnormal accumulation of pericardial fluid will result in cardiac tamponade, requiring drainage. The following report describes a multiple myeloma patient who developed secondary pericardial and pleural effusions, which were surgically drained via a pleuropericardial window.
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16

Bui, Peter V., Sonia N. Zaveri, and J. Rush Pierce Jr. "Sanguineous Pericardial Effusion and Cardiac Tamponade in the Setting of Graves’ Disease: Report of a Case and Review of Previously Reported Cases." Case Reports in Medicine 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/9653412.

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Introduction. Pericardial effusion in the setting of hyperthyroidism is rare. We present a patient with Graves’ disease who developed a sanguineous pericardial effusion and cardiac tamponade.Case Description. A 76-year-old man presenting with fatigue was diagnosed with Graves’ disease and treated with methimazole. Two months later, he was hospitalized for uncontrolled atrial fibrillation. Electrocardiography showed diffuse low voltage and atrial fibrillation with rapid ventricular rate. Chest radiograph revealed an enlarged cardiac silhouette and left-sided pleural effusion. Thyroid stimulatin
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17

Chahine, Johnny, Chandra K. Ala, James L. Gentry, Kevin M. Pantalone, and Allan L. Klein. "Pericardial diseases in patients with hypothyroidism." Heart 105, no. 13 (2019): 1027–33. http://dx.doi.org/10.1136/heartjnl-2018-314528.

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Hypothyroidism is a well-known cause of pericardial effusion (with an incidence of 3%–37%) and can cause cardiac tamponade in severe cases. In this review, we present the current knowledge on the epidemiology of hypothyroid-induced pericardial diseases, the mechanism through which low thyroid hormone levels affect the pericardium, the associated clinical manifestations, diagnostic tests and management options. Hypothyroidism causes pericardial effusion through increased permeability of the epicardial vessels and decreased lymphatic drainage of albumin, resulting in accumulation of fluid in the
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18

Walsh, Rowan F., and Devyani Chowdhury. "Incessant pericardial effusion in a 9 year old male responding to infliximab." Cardiology in the Young 19, no. 4 (2009): 413–15. http://dx.doi.org/10.1017/s1047951109990229.

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AbstractRecurrent idiopathic pericardial effusion can be a challenging medical problem. Multiple medical interventions may yield minimal improvement. We describe a patient with an incessant pericardial effusion that responded to infliximab. The use of infliximab should be considered in the management of recurrent pericardial effusions resistant to other treatment modalities.
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19

Khan, Bakht Umar, Fayaz Ahmed Memon, Muhammad Shehram, Muhammad Shahid, Fahad Khalid, and Nayyar Arif. "Pericardial Effusionin Patients Admitted in Emergency Department: Frequency and Causes." Pakistan Journal of Medical and Health Sciences 16, no. 5 (2022): 1450–52. http://dx.doi.org/10.53350/pjmhs221651450.

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Objective:A study of pericardial effusions in individuals with dyspnea was conducted to evaluate the prevalence and aetiology. Study Design:Prospective/Observational Study Place and Duration: Multicenteric study conducted at DHQ Hospital Bagh AJK/ Federal Govt. Polyclinic Hospital Islamabad and DHQ Teaching Hospital Gujranwala Medical College, Gujranwala. Duration was six months from 1st Oct 2021 to 31st March 2022. Methods:There were 135 patients of both genders had ages 18-75 years were presented in this study. Patients with dyspnea were admitted to emergency department. After obtaining info
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20

Rai, Deependra K., and Abhishek Kumar. "A rare case of cardiac tamponade due to tuberculosis." International Journal of Advances in Medicine 4, no. 1 (2017): 296. http://dx.doi.org/10.18203/2349-3933.ijam20170131.

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Pericardial effusion is an abnormal accumulation of fluid in the pericardial cavity. Because of the limited amount of space in the pericardial cavity, fluid accumulation leads to an increased intrapericardial pressure which can negatively affect heart function. A pericardial effusion with enough pressure to adversely affect heart function is called cardiac tamponade. Pericardial effusion usually results from a disturbed equilibrium between the production and re-absorption of pericardial fluid, or from a structural abnormality that allows fluid to enter the pericardial cavity. Tuberculosis invo
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21

Sanad, Mohammed, Sherif Arafa, Shady Elhusseiny, Mohammed Adel, and Mohammed Elshabrawy Saleh. "Percutaneous drainage of delayed post-cardiac surgery pericardial effusion." Egyptian Cardiothoracic Surgeon 2, no. 3 (2020): 105–13. http://dx.doi.org/10.35810/ects.v2i3.145.

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Background: Pericardial effusion and tamponade are common following valve surgery. The optimal treatment of symptomatic pericardial effusions remains controversial. The objective of this study was to present our experience in non-surgical management of delayed postoperative pericardial effusion.&#x0D; Methods: This retrospective study was conducted on 64 patients who had delayed pericardial effusion after cardiac surgery from 2016 to 2020. Eight patients were excluded due to the presence of inaccessible posterior or clotted pericardial effusion and were managed surgically, and 56 patients had
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Kokulenko, K. V., A. V. Goncharova, and V. A. Kostylev. "Clinical characteristics of dogs with pericardial pathologies accompanied by pericardial effusions." Legal regulation in veterinary medicine, no. 3 (October 14, 2024): 63–66. http://dx.doi.org/10.52419/issn2782-6252.2024.3.63.

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Pericardial effusion is an abnormal accumulation of fluid in the pericardial cavity, which can lead to cardiac tamponade, an acute life–threatening condition of the animal. Cardiac tamponade may be manifested by severe weakness, hypotension and secondary sinus tachycardia. Depending on the causes of pericardial disease and pericardial effusion, the clinical signs can vary greatly from the rate of its accumulation. The purpose of this work is to systematize the clinical signs in dogs with pericardial diseases accompanied by pericardial effusions. All animals were examined according to a techniq
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Reddy Kype, Basava, Archana Pentareddy Sagarika, and Mahesh Rajapantula. "Management of Pericardial and Pleural Effusion in a Dog with Pericardial Mass." Indian Journal of Veterinary Sciences and Biotechnology 21, no. 2 (2025): 122–24. https://doi.org/10.48165/ijvsbt.21.2.26.

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The pericardium is a hard, fibroelastic sac that encloses the heart, with the ability to stretch appreciably in dogs tormented by pericardial effusion (PE) (Lorell and Braunwald, 1984). PE is characterized with the aid of a bizarre buildup of fluid in the pericardial space, at the same time as small volumes of PE won’t produce medical signs and symptoms, will increase in fluid volume and pressure can cause cardiac tamponade. The most common causes of PE in dogs are cardiac neoplasia, right sided heart failure, cardiac rupture, and idiopathic pericarditis and less commonly congenital pericardia
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24

Katyayini, R., and R. Chikkananjaiah. "Cardiac Tamponade in a Patient with Primary Hypothyroidism." Journal of Medical Sciences 1, no. 1 (2015): 7–9. http://dx.doi.org/10.5005/jp-journals-10045-0003.

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ABSTRACT Hypothyroidism is a common disease with multisystem involvement. It may present clinically in various forms.Pericardial effusion (PE) is one of the cardiovascular manifestation. Pericardial effusion is the accumulation of fluid in the pericardial space. The occurrence of pericardial effusion in hypothyroidism appears to be frequent manifestation of severe myxedema, than in mild hypothyroidism. The incidence of pericardial effusion in hypothyroidism is 3 to 6%. However, the incidence of cardiac tamponade in patients with hypothyroidism is rare event. The slow accumulation of liquid in
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25

Elhanafy, Mohamed M., and Dennis D. French. "Atypical Presentation of Constrictive Pericarditis in a Holstein Heifer." Case Reports in Veterinary Medicine 2012 (2012): 1–5. http://dx.doi.org/10.1155/2012/604098.

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The field diagnosis of constrictive pericardial effusion is often established on the pertinent pathognomonic physical examination findings, but the condition cannot be ruled out based on absence of these cardinal signs. Constrictive pericardial effusion is not always manifested by bilateral jugular venous distention and pulsation, brisket edema, and muffled heart sounds, all of which are considered the key points in the field diagnosis of pericardial effusion and hardware disease. This case will also document that the outcomes of hematology, serum biochemistry panels, and blood gas analysis ca
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26

Kesieme, Emeka B., Peter O. Okokhere, Christopher Ojemiega Iruolagbe, Angela Odike, Clifford Owobu, and Theophilus Akhigbe. "Surgical Management of Massive Pericardial Effusion and Predictors for Development of Constrictive Pericarditis in a Resource Limited Setting." Advances in Medicine 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/8917954.

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Background. The diagnosis and treatment of massive pericardial effusion and cardiac tamponade have evolved over the years with a tendency towards a more comprehensive diagnostic workup and less traumatic intervention.Method. We reviewed and analysed the data of 32 consecutive patients who underwent surgery on account of massive pericardial effusion and cardiac tamponade in a semiurban university hospital in Nigeria from February 2010 to February 2016.Results. The majority of patients (34.4%) were between 31 and 40 years. Fourteen patients (43.8%) presented with clinical and echocardiographic f
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27

Soong, Laura C., and Richard M. Haber. "Yellow Nail Syndrome Presenting With a Pericardial Effusion: A Case Report and Review of the Literature." Journal of Cutaneous Medicine and Surgery 22, no. 2 (2017): 190–93. http://dx.doi.org/10.1177/1203475417738970.

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Yellow nail syndrome (YNS) is a constellation of clinical findings including at least 2 of the 3 features of thickened yellow nails, respiratory tract involvement, and lymphedema. We report the case of a middle-aged man presenting with dystrophic, thickened yellow nails; an idiopathic pericardial effusion in the absence of pleural effusion(s); and unilateral apical bronchiectasis found on computed tomography of the chest. This represents a unique presentation of YNS as the first report of a patient with YNS and a pericardial effusion in the absence of pleural effusions and lymphedema and is th
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Lazar, Mihai, Ecaterina Constanta Barbu, Cristina Emilia Chitu, et al. "Pericardial Involvement in Severe COVID-19 Patients." Medicina 58, no. 8 (2022): 1093. http://dx.doi.org/10.3390/medicina58081093.

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Background and Objectives: SARS-CoV-2 has an extensive tissue tropism due to its ability to attach to the surfaces of cells through different receptors, leading to systemic complications. In this article, we aim to present the prevalence of pericardial effusions in patients with severe COVID-19, to identify the risk factors/predictors for pericardial involvement, and to evaluate its impact on overall mortality. Materials and Methods: We enrolled 100 patients with severe COVID-19 in our observational cohort study and divided them in two groups: Group A (27 patients with pericardial effusion) an
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Myachikova, V. Yu, and O. M. Moiseeva. "Differential diagnosis of pericarditis. Part I: Anatomical and physiological characteristics of the pericardium, chest pain syndrome, and pericardial effusion." Russian Journal of Cardiology 30, no. 2 (2025): 6230. https://doi.org/10.15829/1560-4071-2025-6230.

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Inflammatory involvement of the pericardium (ranging from effusion to wall thickening), whether accompanied by chest pain or not, presents challenges not only in diagnosis and therapy, but also in examination, due to the diverse etiologies of pericardial disease.This article reviews current approaches to the diagnosis and treatment of patients with pericardial effusion and pericarditis, which may manifest as chest pain or proceed asymptomatically. Anatomical and physiological characteristics of the pericardium, mechanisms of effusion development and tamponade are described. Diagnostic algorith
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Jianu, Elena, Natalia Motas, Mihnea Davidescu, et al. "Management of neoplastic pericarditis – overview of 156 patients." Pneumologia 69, no. 2 (2020): 97–102. http://dx.doi.org/10.2478/pneum-2020-0020.

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Abstract Introduction Neoplastic pericarditis may develop in any type of cancer, but it is found more frequently in lung cancer, breast cancer and lymphoma. Methods We studied 156 consecutive oncological patients presented with pericardial fluid between 2010 and 2015. Among them, 80 patients were stable, with no indication for pericardial drainage or biopsy, and 76 patients needed surgery to evacuate the pericardium and obtain biopsy. Results Echocardiography and computed tomography were essential in evaluating the topography of the pericardial fluid and the haemodynamic effect, and these inve
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31

Seghrouchni, A., H. Mokhlis, S. El Manir, et al. "PERICARDIAL PUNCTURE: WHEN AND HOW?" International Journal of Advanced Research 9, no. 11 (2021): 323–26. http://dx.doi.org/10.21474/ijar01/13745.

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Pericardial effusion is a very common condition, due to the accumulation of fluid in the pericardial cavity (the impact depends on the volume, rate of accumulation and elasticity of the pericardium), it results in a: 1. Increased intrapericardial pressure. 2. Increase in intracardiac pressure 3. Decrease in ventricular filling 4. Decrease in ejection volume 5. Decrease in cardiac output The etiologies of effusions are diverse. Tamponade requires emergency decompression of the pericardium to achieve hemodynamic stabilization. Two techniques are possible, either percutaneous puncture with or wit
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32

Kim, Soon Bae, Eun Hye Yang, and Ji Hoon Shin. "Percutaneous pericardial catheter drainage for symptomatic uremic pericardial effusions with narrow safety margins." PLOS ONE 17, no. 10 (2022): e0276498. http://dx.doi.org/10.1371/journal.pone.0276498.

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Background Percutaneous pericardial catheter drainage (PCD) for pericardial effusion is generally known to be limited by the high risk associated with effusions that are less than 10 mm thick. The objective was to report cases who underwent percutaneous PCD for symptomatic uremic pericardial effusions, which were less than 10 mm thick after cardiologist declined to perform the PCDs because of the narrow safety margins. Materials and methods Thirteen consecutive cases (11 patients) (median age, 56 years, range, 31–83) with symptomatic uremic pericardial effusion (thickness &lt;10 mm) affecting
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Restrepo, Michel Hernández, Hernando Bernal Franco, Cristian Hernández Pérez, and Guillermo Granados González. "Decoding Pericardial Effusion: Ultrasonographic Insights for Radiologists." Contemporary Diagnostic Radiology 46, no. 18 (2023): 1–8. http://dx.doi.org/10.1097/01.cdr.0000947744.97759.1e.

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Pericardial effusion is a common finding in clinical practice. It can present incidentally asymptomatically or as a manifestation of systemic or cardiac disease. According to its commitment, it can be classified into mild effusions, generally asymptomatic, up to cardiac tamponade, which can endanger the patient's life. Recent advances make it possible to establish the presence and assess the size of the pericardial effusion, its hemodynamic impact, and clarify the etiology. The aim of this article is to provide an update on the diagnostic and therapeutic approach to pericardial effusion.
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Bhattacharya, Gita, and Pritha P. Gupta. "A Case Report of Pericardial Effusion with False-Positive Mesothelioma and Adenocarcinoma Markers as the Initial Presentation of Systemic Lupus Erythematous." Case Reports in Rheumatology 2022 (November 3, 2022): 1–5. http://dx.doi.org/10.1155/2022/8081055.

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Pericardial effusion or the accumulation of fluid in the pericardial sac, can result from infectious, malignant, or autoimmune processes such as systemic lupus erythematous (SLE). However, pericardial effusion is infrequently the first presentation of SLE. Here, we describe the case of a 54-year-old African American woman who presented with hypertensive emergency and was found to have pericardial effusion on echocardiogram. Her hypertensive symptoms resolved with medical management and a work up were positive for serum markers of SLE and mesothelioma cell markers (calretinin, CK 5/6) and adeno
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Rachmawati, Pediana, Indah K. Murni, Sasmito Nugroho, Noormanto Noormanto, and Sumadiono Sumadiono. "Factors associated with pericardial effusion in pediatric systemic lupus erythematosus." Paediatrica Indonesiana 58, no. 5 (2018): 227–32. http://dx.doi.org/10.14238/pi58.5.2018.227-32.

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Background Cardiovascular involvement in systemic lupus erythematosus (SLE) has been reported to range from 4-78%. Complications can affect all structures of the heart, including the endocardium, myocardium, pericardium, and valves. Pericarditis is the most common manifestation, with an incidence of 11-54% in SLE patients. Pericardial effusion is often observed in patients with pericarditis, and can be confirmed by echocardiography.&#x0D; Objective To determine factors associated with pericardial effusion in children with SLE.&#x0D; Methods We conducted a restrospective cross-sectional study b
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Shafira Nurul Annisa and Rini Istisakinah. "Presentation of Pericardial Effusion in an 18-Year-Old Female with Systemic Lupus Erythematosus." Indonesian Journal of General Medicine 10, no. 1 (2025): 35–47. https://doi.org/10.70070/y720em20.

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Background: Pericardial effusion is a common manifestation of Systemic Lupus Erythematosus (SLE), a chronic autoimmune disease affecting young women. This rare symptom requires high suspicion and prompt diagnosis for appropriate treatment, emphasizing the importance of early detection and management. Case Description: A patient with pericardial effusion presented to the emergency department with symptoms such as weakness, mouth ulcers, and nausea. Despite no known medical conditions, a chest X-ray revealed cardiomegaly, suggesting an underlying cardiovascular condition. An echocardiographic ev
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Szturmowicz, M., W. Tomkowski, A. Fijalkowska, et al. "Diagnostic Utility of Cyfra 21-1 and Cea Assays in Pericardial Fluid for the Recognition of Neoplastic Pericarditis." International Journal of Biological Markers 20, no. 1 (2005): 43–49. http://dx.doi.org/10.1177/172460080502000107.

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A positive cytology result in pericardial fluid is the gold standard for recognition of malignant pericardial effusion. Unfortunately, in 30–50% of patients with malignant pericardial effusion cytological examination of the pericardial fluid is negative. Tumor marker assessment in pericardial fluid may help to recognize malignant pericardial effusion. The aim of our study was to estimate the value of CYFRA 21-1 and CEA measurement in pericardial fluid for the recognition of malignant pericardial effusion. To our knowledge this is the first study on CYFRA 21-1 assessment in pericardial effusion
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Westin, Oscar, and Abbas Ali Qayyum. "Recurrent Episodes of Pericardial Effusion as Isolated Manifestation of Tuberculosis: Case Report." Current Medical Imaging Formerly Current Medical Imaging Reviews 15, no. 1 (2018): 78–80. http://dx.doi.org/10.2174/1573405613666170619093338.

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Background: Recurrent episodes of isolated pericardial effusion due to tuberculosis, leading to reduced Left Ventricle Ejection Fraction (LVEF), are uncommon. Methods: This is a case report of a previously healthy 32-years old male with tuberculous induced pericardial effusion as isolated manifestation. The only known exposure of tuberculosis was a brother with whom the patient did not have physical contact during the last year. The pericardial effusion repeatedly appeared after being drained a total of three times. Due to recurrent episodes of pericardial effusion, severe thickening of the pe
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Borregaard, Britt, Kirstine Lærum Sibilitz, Marc Gjern Weiss, et al. "Occurrence and predictors of pericardial effusion requiring invasive treatment following heart valve surgery." Open Heart 9, no. 1 (2022): e001880. http://dx.doi.org/10.1136/openhrt-2021-001880.

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ObjectivesTo describe the occurrence of significant pericardial effusion, and to investigate characteristics associated with pericardial effusion within three months following heart valve surgery.MethodsA retrospective, observational cohort study including adult patients undergoing heart valve surgery at Odense University Hospital from August 2013 to November 2017. Data were gathered from The Western Denmark Heart Registry and electronic patient records.Cox proportional hazard models were used to investigate the associations between characteristics associated with significant pericardial effus
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Leehey, D. J., J. T. Daugirdas, S. Popli, V. C. Gandhi, R. Pifarré, and T. S. Ing. "Predicting Need for Surgical Drainage of Pericardial Effusion in Patients with End-Stage Renal Disease." International Journal of Artificial Organs 12, no. 10 (1989): 618–25. http://dx.doi.org/10.1177/039139888901201004.

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The best approach to treatment of pericarditis accompanied by substantial pericardial effusion in end-stage renal disease (ESRD) patients is unknown. In a review of our experience, we found that ESRD patients with moderate-to-large or large (circa 250 mL or larger) pericardial effusions usually failed to improve with intensive dialysis and ultimately required surgical drainage of the effusion. Multivariate analysis revealed that effusion size was by far the most important factor predicting need for surgery. Since early pericardial drainage obviates the risk of sudden tamponade, we recommend th
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Qasba, Ruman K., Busra Cangut, Amnah Alhazmi, et al. "Surgical Management Strategies for Pericardial Effusion—A Systematic Review." Journal of Clinical Medicine 14, no. 14 (2025): 4985. https://doi.org/10.3390/jcm14144985.

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Objectives: Pericardial effusion is the accumulation of excess fluid in the pericardial sac. The etiology is multi-factorial and different techniques are used for management, including subxiphoid approaches, anterior and lateral thoracotomies, video-assisted thoracic surgery (VATS), and percutaneous pericardiocentesis. We evaluate the surgical management strategies for pericardial effusion and their outcomes in this systematic review. Methods: A systematic literature review was performed to identify studies on the surgical management of pericardial effusion from inception to February 2024 usin
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Connaire, Stephanie, Elena Elchinova, Chiara Bucciarelli-Ducci, and Philip Campbell. "Cardiac tamponade secondary to Dressler’s syndrome." BMJ Case Reports 14, no. 8 (2021): e243577. http://dx.doi.org/10.1136/bcr-2021-243577.

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A 56-year-old woman presented to hospital with chest pain. Following review and investigations in the medical assessment unit, she was diagnosed with costochondritis and discharged home. She represented 10 days later and was mottled and hypotensive with a high lactate, raised inflammatory markers, an acute kidney injury and bilateral loin pain. A CT of the thorax, abdomen and pelvis showed pleural effusions and a large pericardial effusion with features of cardiac tamponade on subsequent echocardiography. A pericardiocentesis was performed and she was admitted to intensive care for haemofiltra
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Huang, Jing-bin, Zhao-ke Wen, Wei-jun Lu, Chang-chao Lu, and Xian-ming Tang. "Preoperative Pericardial Effusion is Associated with Low Cardiac Output Syndrome After Pericardiectomy for Constrictive Pericarditis." Heart Surgery Forum 24, no. 3 (2021): E427—E432. http://dx.doi.org/10.1532/hsf.3813.

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Background: Low cardiac output syndrome is the main cause of death after pericardiectomy. Methods: Patients who underwent pericardiectomy for constrictive pericarditis from January 2009 to October 2020 at our hospital were included in the study. Histopathologic studies of pericardium tissue from every patient were performed. All survivors were followed up. Results: Ninety-two consecutive patients underdoing pericardiectomy were included in the study. The incidence of postoperative low cardiac output syndrome was 10.7% (10/92). There were five operative deaths. Mortality and incidence of LCOS i
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Marchiori, Edson, Bruno Hochhegger, and Gláucia Zanetti. "Pericardial effusion." Jornal Brasileiro de Pneumologia 47, no. 1 (2021): e20200587-e20200587. http://dx.doi.org/10.36416/1806-3756/e20200587.

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Zhang, J., and B. Khan. "Pericardial effusion." BMJ 350, jun17 11 (2015): h2893. http://dx.doi.org/10.1136/bmj.h2893.

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Bilal, Jawad, Eric P. Gall, and Laura Meinke. "Pericardial Effusion." JCR: Journal of Clinical Rheumatology 23, no. 5 (2017): 296–97. http://dx.doi.org/10.1097/rhu.0000000000000573.

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SILVA, FRIEDA, LOURDES GARCÍA, CHARLIE FLORES, DAVID STORER, and FRANCISCO AGUILÓ. "Pericardial Effusion." Clinical Nuclear Medicine 21, no. 3 (1996): 218–20. http://dx.doi.org/10.1097/00003072-199603000-00007.

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Azarbal, Amir, and Martin M. LeWinter. "Pericardial Effusion." Cardiology Clinics 35, no. 4 (2017): 515–24. http://dx.doi.org/10.1016/j.ccl.2017.07.005.

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Zeller, John L., Cassio Lynm, and Richard M. Glass. "Pericardial Effusion." JAMA 297, no. 16 (2007): 1844. http://dx.doi.org/10.1001/jama.297.16.1844.

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Schoenfeld, David W. "Pericardial Diseases." DeckerMed Emergency Medicine, May 21, 2018. http://dx.doi.org/10.2310/em.4025.

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Diseases of the pericardium represent a wide range of clinical syndromes that vary substantially in severity, from a benign pericardial effusion to fatal constrictive pericarditis or hemopericardium. Acute pericarditis is the most common pericardial disease, with viral and idiopathic as the most frequent etiologies. Typically, acute pericarditis can be managed as an outpatient with dual-agent therapy consisting of aspirin or nonsteroidal anti-inflammatory drug plus colchicine and rarely requires admission. Pericardial effusions are fluid collections in the pericardial cavity. They are a common
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